MCID: BRX001
MIFTS: 49

Bruxism malady

Categories: Mental diseases, Oral diseases

Aliases & Classifications for Bruxism

About this section

Aliases & Descriptions for Bruxism:

Name: Bruxism 11 27 50 39 13 68
Sleep Bruxism 39 68
Bruxism - Teeth Grinding 11
Sleep Related Bruxism 11
 
Sleep-Related Bruxism 68
Teeth Grinding 11
Grinding Teeth 11

Classifications:



External Ids:

Disease Ontology11 DOID:2846
ICD1030 F45.8, G47.63
ICD9CM32 327.53
NCIt45 C73511

Summaries for Bruxism

About this section
Wikipedia:71 Bruxism is excessive teeth grinding or jaw clenching. It is an oral parafunctional activity; i.e., it is... more...

MalaCards based summary: Bruxism, also known as sleep bruxism, is related to oromandibular dystonia and teratoma with malignant transformation, and has symptoms including sleep disturbances, sleep disturbances and toothache. An important gene associated with Bruxism is DRD2 (Dopamine Receptor D2), and among its related pathways are Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Affiliated tissues include brain, eye and bone, and related mouse phenotype integument.

Disease Ontology:11 A sleep disorder that involves involuntarily grinding or clenching of the teeth while sleeping.

Related Diseases for Bruxism

About this section

Diseases related to Bruxism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1oromandibular dystonia10.8
2teratoma with malignant transformation10.2DRD2, HTR2A
3headache10.2
4intracranial cavernous angioma10.1DRD2, SLC6A4
5cerebellar liponeurocytoma10.1HTR2A, MECP2
6allergic hypersensitivity disease10.1DRD2, HTR2A
7ornithosis10.1DRD2, SLC6A4
8vascular cancer10.1DRD2, HTR2A
9apperceptive agnosia10.1DRD2, SLC6A4
10colorectal adenocarcinoma10.1DRD2, SLC6A4
11strongyloidiasis10.1DRD2, SLC6A4
12interstitial emphysema10.1DRD2, SLC6A4
13nephrogenic adenoma of the urethra10.1DRD2, SLC6A4
14nephronophthisis 1310.1HTR2A, SLC6A4
15spinal meningioma10.1DRD2, HTR2A
16dry eye syndrome10.1HTR2A, SLC6A4
17neurogenic bladder10.0HTR2A, SLC6A4
18intrahepatic gall duct cancer10.0HTR2A, SLC6A4
19sleep apnea10.0
20hypoglycemic coma10.0HTR2A, SLC6A4
21obstructive sleep apnea10.0
22cervicitis10.0
23multiple personality disorder10.0HTR2A, SLC6A4
24sleep disorder10.0
25primary angle-closure glaucoma10.0HTR2A, SLC6A4
26splenic abscess10.0DRD2, HTR2A, SLC6A4
27pyromania10.0DRD2, HTR2A, SLC6A4
28transmitted_by10.0DRD2, SLC6A4
29waardenburg's syndrome10.0DRD2, HTR2A, SLC6A4
30cytomegalic congenital adrenal hypoplasia10.0DRD2, HTR2A, SLC6A4
31postencephalitic parkinson disease10.0DRD2, HTR2A, SLC6A4
32cecal benign neoplasm9.9DRD2, HTR2A, SLC6A4
33hereditary multiple exostoses9.9DRD2, HTR2A, SLC6A4
34hepatitis d9.9DRD2, HTR2A, SLC6A4
35retinoblastoma9.9DRD2, HTR2A, SLC6A4
36chronic conjunctivitis9.9DRD2, HTR2A, SLC6A4
37benign epilepsy with centrotemporal spikes9.9DRD2, HTR2A, SLC6A4
38bartter disease9.9HTR2A, MECP2, SLC6A4
39microcephaly 13, primary, autosomal recessive9.9DRD2, HTR2A, SLC6A4
40gastroesophageal reflux9.9
41cerebral palsy9.9
42cerebritis9.9
43brain glioblastoma multiforme9.9DRD2, HTR2A, SLC6A4
44hepatitis b reinfection following liver transplantation9.9HTR2A, SLC6A4
45keratosis9.9HTR2A, SLC6A4
46preeclampsia/eclampsia 59.9DRD2, HTR2A, SLC6A4
47carotid stenosis9.9DRD2, SLC6A4
48brain injury9.9
49periodontitis9.9
50myoclonus9.9

Graphical network of the top 20 diseases related to Bruxism:



Diseases related to bruxism

Symptoms & Phenotypes for Bruxism

About this section

UMLS symptoms related to Bruxism:


sleep disturbances, toothache, teeth chattering, mental and behavioral signs and symptoms, excessive daytime somnolence, sleeplessness

MGI Mouse Phenotypes related to Bruxism according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.3DRD2, FRRS1L, KLF7, MECP2, SLC6A4

Drugs & Therapeutics for Bruxism

About this section

Drugs for Bruxism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 51)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AcetylcholineapprovedPhase 4, Phase 180551-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
O-Acetylcholine
acetylcholine chloride
2
Lidocaineapproved, vet_approvedPhase 41317137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
3onabotulinumtoxinAPhase 4, Phase 1652
4Peripheral Nervous System AgentsPhase 4, Phase 123689
5abobotulinumtoxinAPhase 4, Phase 1652
6Neurotransmitter AgentsPhase 4, Phase 118340
7Neuromuscular AgentsPhase 4, Phase 11180
8Botulinum ToxinsPhase 4, Phase 1697
9Botulinum Toxins, Type APhase 4, Phase 1657
10Cholinergic AgentsPhase 4, Phase 13992
11incobotulinumtoxinAPhase 4, Phase 1662
12Central Nervous System DepressantsPhase 413403
13Sodium Channel BlockersPhase 41593
14Diuretics, Potassium SparingPhase 41917
15Anesthetics, LocalPhase 43492
16Anti-Arrhythmia AgentsPhase 43093
17AnestheticsPhase 49596
18
Salicylic acidapproved, vet_approvedPhase 3, Phase 1, Phase 2, Early Phase 118969-72-7338
Synonyms:
105910_ALDRICH
105910_SIAL
2 Hydroxybenzoic Acid
2-Carboxyphenol
2-Hydroxybenzenecarboxylate
2-Hydroxybenzenecarboxylic acid
2-Hydroxybenzoate
2-Hydroxybenzoic acid
2-hydroxy(1-14c)benzoic acid
247588_SIAL
27301_SIAL
69-72-7
7681-06-3
8052-31-1
84210_FLUKA
84210_SIAL
AB1002436
AC1L190M
AC1Q1HCK
AC1Q72IF
AI3-02407
AKOS000118979
ALPHA/BETA HYDROXY ACIDS (SALICYLIC ACID) (SEE ALPHA/BETA HYDROXY ACIDS)
AR-1E2203
ATA fraction 10, ammonium salt
Acid, 2-Hydroxybenzoic
Acid, Salicylic
Acid, o-Hydroxybenzoic
Acid, ortho-Hydroxybenzoic
Acido o-idrossibenzoico
Acido o-idrossibenzoico [Italian]
Acido salicilico
Acido salicilico [Italian]
Acidum salicylicum
Advanced Pain Relief Callus Removers
Advanced Pain Relief Corn Removers
Advanced pain relief callus removers
Advanced pain relief corn removers
Akurza Cream
Akurza Lotion
Alpha/Beta Hydroxy Acids (Glycolic Acid, Salicylic Acid)
BENZOIC ACID,2-HYDROXY SALICYLIC ACID
BIDD:ER0602
BRN 0774890
Benzoic acid, 2-hydroxy- (9CI)
C00805
CCRIS 6714
CHEBI:16914
CHEMBL424
CID338
CMC_13852
Caswell No. 731
Clear away Wart Remover
Clear away wart remover
Compound W
Compound w
D00097
D020156
DB00936
DHS Sal Shampoo
DivK1c_000301
Domerine
Dr. Scholl'S Callus Removers
Dr. Scholl'S Corn Removers
Dr. Scholl'S Wart Remover Kit
Dr. Scholl's callus removers
Dr. Scholl's corn removers
Dr. Scholl's wart remover kit
DuoPlant Gel
Duofil Wart Remover
Duofil wart remover
Duofilm
Duoplant
E9A559BE-383B-4F83-BC02-3031D03D558A
EINECS 200-712-3
EPA Pesticide Chemical Code 076602
Freezone
H0206
HSDB 672
Hydrisalic Gel
I04-0192
IDI1_000301
InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10
Ionil
Ionil Plus
Ionil plus
Ionil-Plus
 
K 537
K 557
KBio1_000301
KBio2_001428
KBio2_003996
KBio2_006564
KBioSS_001428
Keralyt
Kyselina 2-hydroxybenzoova
Kyselina 2-hydroxybenzoova [Czech]
Kyselina salicylova
Kyselina salicylova [Czech]
LS-2169
MLS000069653
Mediplast pads
MolPort-001-769-476
NCGC00159447-02
NCGC00159447-04
NINDS_000301
NSC 180
NSC180
NSC629474
O-Carboxyphenol
O-Hydroxybenzoate
O-Hydroxybenzoic acid
O-carboxyphenol
O-hydroxybenzoic acid
Occlusal
Oprea1_040343
Orthohydroxybenzoic acid
P&S Shampoo
Phenol-2-carboxylate
Phenol-2-carboxylic acid
Propa pH Peel-Off Acne Mask
Psoriacid-S-Stift
Psoriacid-S-stift
Retarder SAX
Retarder W
Rutranex
S5922_SIGMA
S7401_SIGMA
S8519_SIGMA
SALICYLIC ACID (SEE ALSO ALPHA HYDROXY ACIDS)
SALICYLIC ACID, ACS
SAX
SBB052826
SGCUT00012
SMP2_000145
SMR000059163
STK258681
Salex Cream
Salex Lotion
Salicyclic acid
Salicylate
Salicylic acid
Salicylic acid & Sulfur Soap
Salicylic acid (6CI,8CI)
Salicylic acid (JP15/USP)
Salicylic acid (TN)
Salicylic acid Soap
Salicylic acid [USAN:JAN]
Salicylic acid collodion
Salicylic acid soap
Salicylic acid, tech
Salicylic acid, tech.
Salicylic acid-ring-UL-14C
Saligel
Salonil
Sebucare
Sebulex
Spectrum_000948
Stri-Dex
Trans-Ver-Sal
UNII-O414PZ4LPZ
UPCMLD-DP126
UPCMLD-DP126:001
Verrugon
W398500_ALDRICH
WLN: QVR BQ
bmse000252
o Hydroxybenzoic Acid
o-Carboxyphenol
o-hydroxybenzoic acid
ortho Hydroxybenzoic Acid
ortho-Hydroxybenzoic Acid
phenol derivative, 7
salicylate
salicylic acid
to_000004
19Lemon BalmNutraceuticalPhase 316
20PokeNutraceuticalPhase 34
21
Miconazoleapproved, investigational, vet_approvedPhase 1, Phase 2, Early Phase 1370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
22Keratolytic AgentsPhase 1, Phase 2, Early Phase 1444
23Anti-Infective AgentsPhase 1, Phase 2, Early Phase 122062
24Dermatologic AgentsPhase 1, Phase 2, Early Phase 15806
25Antifungal AgentsPhase 1, Phase 2, Early Phase 13696
26
Buspironeapproved, investigational4736505-84-72477
Synonyms:
36505-84-7
8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione
8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione
8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione
AB00053432
AC1L1DRN
AKOS002313325
Ansial
Ansiced
Anxiron
Axoren
BAS 00928841
BIDD:GT0519
BPBio1_000547
BPBio1_001403
BRD-K93461745-001-01-5
BRD-K93461745-003-03-7
BRN 0964904
BSPBio_000497
Bespar
Biomol-NT_000108
Buspiron
Buspirona
Buspirona [INN-Spanish]
Buspirone
Buspirone (INN)
Buspirone [INN:BAN]
Buspirone-MDTS
Buspironum
Buspironum [INN-Latin]
Buspisal
C06861
C13H21NO2.C9H14N4
CAS-33386-08-2
CHEBI:3223
CHEMBL49
 
CID2477
D07593
DB00490
DivK1c_000921
EINECS 253-072-2
Gen-Buspirone
Gen-Buspirone (TN)
HMS2090K19
IDI1_000921
KBio1_000921
KBio2_002236
KBio2_004804
KBio2_007372
KBioSS_002236
L001110
LS-22723
Lopac-B-7148
Lopac0_000223
MJ-9022-1
MolPort-002-539-709
N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-1-cyclopentanediacetamide
NCGC00015162-01
NCGC00015162-06
NCGC00016820-01
NCGC00024905-01
NCGC00024905-02
NCGC00024905-03
NINDS_000921
Prestwick0_000369
Prestwick1_000369
Prestwick2_000369
Prestwick3_000369
SPBio_002418
STK086268
STOCK1S-11244
Spectrum_001756
Tocris-0962
UNII-TK65WKS8HL
buspirone
27
Clonidineapproved2404205-90-72803
Synonyms:
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- (9CI)
2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
2,6-dichloro-N-(2-imidazolidinylidene)aniline
2,6-dichloro-N-2-imidazolidinylidenebenzenamide
2,6-dichloro-N-imidazolidin-2-ylideneaniline
2-((2,6-Dichlorophenyl)imino)imidazolidine
2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2)
2-(2,6-Dichloroanilino)-2-imidazoline
2-(2,6-Dichlorophenylamino)-2-imidazoline
2-(2,6-Dichlorophenylimino)imidazolidine
2-Imidazoline, 2-(2,6-dichloroanilino)- (7CI,8CI)
2-[(2,6-Dichlorophenyl)imino]imidazoline
2-[(2,6-dichlorophenyl)imino]-2-imidazoline
4205-90-7
4205-91-8 (mono-hydrochloride)
57066-25-8
734571A
AB00514634
AC1L1EI5
AC1Q3K6V
AKOS001595470
Adesipress
BIDD:GT0547
BPBio1_000040
BRD-K98530306-001-02-1
BRD-K98530306-003-05-0
BSPBio_000036
BSPBio_001588
BSPBio_002055
Bio1_000470
Bio1_000959
Bio1_001448
Bio2_000308
Bio2_000788
C9H9Cl2N3
CAS-4205-91-8
CATAPRES-TTS-1
CATAPRES-TTS-2
CATAPRES-TTS-3
CCRIS 7787
CHEBI:3757
CHEBI:46632
CHEMBL134
CID2803
Catapres
Catapres- TTS
Catapres-TTS
Catapresan
Catapressan
Catarpres
Catarpres-TTS
Catarpres-TTS (TN)
Catarpresan
Chlofazoline
Chlornidinum
Clofenil
Clonidin
Clonidina
Clonidina [INN-Spanish]
Clonidine (JAN/USAN/INN)
Clonidine HCl
Clonidine [USAN:BAN:INN]
Clonidinhydrochlorid
Clonidinum
Clonidinum [INN-Latin]
Clonistada
Clopheline
D00281
DB00575
DB07566
DivK1c_000774
 
Dixarit
Duraclon
Duraclont
EINECS 224-119-4
Gemiton
HMS1361P10
HMS1791P10
HMS1989P10
HMS2089G11
HSDB 3040
Hemiton
IDI1_000774
IDI1_034058
Ipotensium
Isoglaucon
KBio1_000774
KBio2_000308
KBio2_001821
KBio2_002876
KBio2_004389
KBio2_005444
KBio2_006957
KBio3_000615
KBio3_000616
KBio3_001275
KBioGR_000308
KBioGR_001572
KBioSS_000308
KBioSS_001821
Klofelin
Klofenil
L000193
LS-79606
Lopac-C-7897
Lopac0_000268
M 5041T
M-5041T
MolPort-001-779-668
MolPort-005-932-374
N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
NCGC00015268-01
NCGC00015268-02
NCGC00015268-08
NCGC00024734-01
NCGC00024734-02
NCGC00024734-03
NCGC00024734-04
NCGC00024734-05
NCGC00179680-01
NINDS_000774
Prestwick0_000248
Prestwick1_000248
Prestwick2_000248
Prestwick3_000248
SKF 34427
SPBio_001233
SPBio_002255
ST 155BS
ST-155-BS
ST-155BS
Spectrum2_001187
Spectrum3_000358
Spectrum4_000956
Spectrum5_000759
Spectrum_001341
T171
Tenso-Timelets
Tocris-0690
UNII-MN3L5RMN02
ZINC00896484
clonidine
nchembio.79-comp11
nchembio705-10
28
Hydrocortisoneapproved, vet_approvedEarly Phase 166750-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
29
Butyric AcidexperimentalEarly Phase 1380107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
1-propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
Butyric acid
 
Butyricum acidum
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
N-butanoic acid
N-butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
30Pharmaceutical Solutions8192
31Tranquilizing Agents4265
32Antimanic Agents814
33Antidepressive Agents2736
34Psychotropic Drugs6430
35Lithium carbonate240554-13-2
36Analgesics11733
37Sympatholytics580
38Adrenergic Agonists3027
39Adrenergic Agents5352
40
Serotonin362750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
41Serotonin Agents3156
42Anti-Anxiety Agents1885
43Adrenergic alpha-2 Receptor Agonists980
44Antihypertensive Agents4207
45Autonomic Agents10150
46Adrenergic alpha-Agonists1734
47Hydrocortisone-17-butyrateEarly Phase 1332
48Hydrocortisone acetateEarly Phase 1667
49Hydrocortisone 17-butyrate 21-propionateEarly Phase 1667
50Anti-Inflammatory AgentsEarly Phase 110729

Interventional clinical trials:

(show all 35)
idNameStatusNCT IDPhase
1Study of the Safety and Efficacy of Botox in BruxismUnknown statusNCT00908050Phase 4
2Effects of Botulinum Toxin Type A(Meditoxin®) on Sleep BruxismUnknown statusNCT01336439Phase 4
3Nocturnal Mouth Guards, SOVA vs. Standard Acrylic Orthotic; Phase IVCompletedNCT02340663Phase 4
4Oral Appliance in Obstructive Sleep Apnea. A Randomized Controlled Blinded Multicenter Study Comparing Two DevicesEnrolling by invitationNCT02148510Phase 4
5Efficacy of Botulinum Toxin Versus Lidocaine in Treating Masticatory Myofascial Face Pain Using Ultrasound and EMG Guided TechniquesTerminatedNCT00992108Phase 4
6Postoperative Hypersensitivity Randomized Comparative Effectiveness Research TrialCompletedNCT01268605Phase 3
7Efficacy of Phytolacca Decandra and Melissa Officinalis in Children With Nocturnal BruxismActive, not recruitingNCT02870543Phase 3
8The Influence of Oral Vibrational Stimulation on Cognitive Function of Elderly IndividualsUnknown statusNCT02332525Phase 1, Phase 2
9Physiotherapy on the Airway of Bruxist ChildrenCompletedNCT01178229Phase 1, Phase 2
10Occlusal Adjustment as Treatment for Chronic Orofacial PainCompletedNCT00899717Phase 1, Phase 2
11Botox for Treatment of TMJ Disorder With BruxismUnknown statusNCT02202070Phase 1
12Relationship of Facial Pattern With BruxismUnknown statusNCT00868244
13TMJ NextGen Pilot Study to Treat Subjects With BruxismUnknown statusNCT02446288
14Reduction of Masticatory Muscle Activity by Restoring Canine GuidanceUnknown statusNCT02235220
15Analysis of the Prevalence and Characteristics of Concomitant Sleep and Headache Disorders, and the Efficacy of CPAP Treatment for Headache Among Those Patients Diagnosed With Obstructive Sleep ApneaUnknown statusNCT00520156
16Respiratory Problems and Caries in Children With BruxismCompletedNCT01463826
17Comparative Evaluation of Gabapentine and Occlusal Splint in the Management of Sleep BruxismCompletedNCT01255878
18Treatment Sleep Bruxism With the Luco Hybrid OSA ApplianceCompletedNCT02882880
19Floral Remedies for Sleep-bruxism PatientsCompletedNCT03112954
20TMJ NextGeneration(TM) Feasibility StudyCompletedNCT02257320
21Effects of the Continuous Wear of Invisalign® Trays on the Temporomandibular Joints and Orofacial Muscular ComplexCompletedNCT01812850
22A Clinical Trial of the Optimal Treatment Period and Long-term Efficacy of Functional Electrical Stimulation (FES) on Sleep BruxismCompletedNCT01000389
23Effects of Dry Needling in Patients With Sleep Bruxism and Temporomandibular Disorders: a Prospective Case SeriesCompletedNCT02587182
24Conservative Treatment of Patients With Temporomandibular DisordersCompletedNCT01021306
25Prevalence of Bruxism in a Group of Preschool Egyptian ChildrenRecruitingNCT03006133
26All-ceramic Crowns in Patients With Sleep BruxismRecruitingNCT03039985
27Sleep Bruxism and (Peri-)Implant ComplicationsRecruitingNCT02410681
28Restoring Masticatory Function to Treat Chronic PainRecruitingNCT02144233
29Physical Therapy Interventions Relative to Dental Treatment in Individuals With BruxismActive, not recruitingNCT01778881
30Evaluation of Selected Disorders With Sleep BruxismEnrolling by invitationNCT03083405
31Evaluation of Muscle Activity, Bite Force and Salivary Cortisol in Children With BruxismNot yet recruitingNCT02757261Early Phase 1
32Clinical Efficacy of Crowns Fabricated Using LuxaCrownNot yet recruitingNCT03160950
33Treatment Period and Long-term Efficacy of Functional Electrical Stimulation (FES) on Sleep BruxismTerminatedNCT01005511
34Treatment Period and Long-term Effect of Functional Electric Stimulation (FES) for BruxismTerminatedNCT00807430
35TMJ-1001 Bruxism Run-In/Pivotal TrialWithdrawnNCT02269553

Search NIH Clinical Center for Bruxism


Cochrane evidence based reviews: sleep bruxism

Genetic Tests for Bruxism

About this section

Genetic tests related to Bruxism:

id Genetic test Affiliating Genes
1 Bruxism27

Anatomical Context for Bruxism

About this section

MalaCards organs/tissues related to Bruxism:

36
Brain, Eye, Bone, Heart, Testes, Pineal, Kidney

Publications for Bruxism

About this section

Articles related to Bruxism:

(show top 50)    (show all 609)
idTitleAuthorsYear
1
Sleep and awake bruxism in adults and its relationship with temporomandibular disorders: A systematic review from 2003 to 2014. (27796166)
2017
2
Relationship between obstructive sleep apnoea syndrome and sleep bruxism: a systematic review. (27977045)
2017
3
Therapies for bruxism: a systematic review and network meta-analysis (protocol). (28086992)
2017
4
Brexism and bruxism. (27982009)
2016
5
Dentists' knowledge of occlusal splint therapy for bruxism and temporomandibular joint disorders. (27251967)
2016
6
Short-term effects of repetitive transcranial magnetic stimulation on sleep bruxism - a pilot study. (27025267)
2016
7
Error in Calculation of Predictive Values in Paper on Screening for Sleep Bruxism. (26888593)
2016
8
Cross-sectional study of anxiety symptoms and self-report of awake and sleep bruxism in female TMD patients. (27097685)
2016
9
A randomised, open-label, crossover study of the dopamine agonist, pramipexole, in patients with sleep bruxism. (27426276)
2016
10
Methadone maintenance treatment may be associated with bruxism in male prisoners. (27855842)
2016
11
Association between patterns of jaw motor activity during sleep and clinical signs and symptoms of sleep bruxism. (27996170)
2016
12
Correction to To see bruxism: a functional MRI study. (26975898)
2016
13
Self-Reported Bruxism and Symptoms of Temporomandibular Disorders in Finnish University Students. (27792798)
2016
14
Botulinum Toxin Type A as Preoperative Treatment for Immediately Loaded Dental Implants Placed in Fresh Extraction Sockets for Full-Arch Restoration of Patients With Bruxism. (27092916)
2016
15
Sleep bruxism: challenges and restorative solutions. (27217798)
2016
16
Current Treatments of Bruxism. (26897026)
2016
17
Bruxism is a continuously distributed behaviour, but disorder decisions are dichotomous (Response to letter by Manfredini, De Laat, Winocur, & Ahlberg (2016)). (27558868)
2016
18
Sleep bruxism associated with obstructive sleep apnoea syndrome - A pilot study using a new portable device. (27567051)
2016
19
Grinding patterns in migraine patients with sleep bruxism: a case-controlled study. (27077249)
2016
20
Impact of Bruxism on Ceramic Defects in Implant-Borne Fixed Dental Prostheses: A Retrospective Study. (27148995)
2016
21
The Association between Headaches and Temporomandibular Disorders is Confounded by Bruxism and Somatic Complaints. (28002094)
2016
22
Intricate Assessment and Evaluation of Effect of Bruxism on Long-term Survival and Failure of Dental Implants: A Comparative Study. (27659086)
2016
23
Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism. (27916472)
2016
24
Bruxism and dental implant failures: a multilevel mixed effects parametric survival analysis approach. (27611304)
2016
25
A survey on the potential relationships between TMD, possible sleep bruxism, unilateral chewing, and occlusal factors in Turkish university students. (27707365)
2016
26
Different association between specific manifestations of bruxism and temporomandibular disorder pain. (27687043)
2016
27
Perceived stress and bruxism in university students. (28003024)
2016
28
Sleep bruxism is related to decreased inhibitory control of trigeminal motoneurons, but not with reticulobulbar system. (27629540)
2016
29
Effect of mandibular advancement device on sleep bruxism score and sleep quality. (27422230)
2016
30
Bruxism and dental implant treatment complications: a retrospective comparative study of 98 bruxer patients and a matched group. (27009853)
2016
31
Effects of myofascial trigger point dry needling in patients with sleep bruxism and temporomandibular disorders: a prospective case series. (27697769)
2016
32
Diagnostic validity of self-reported measures of sleep bruxism using an ambulatory single-channel EMG device. (26876908)
2016
33
Association between Self-Reported Bruxism and Sleeping Patterns among Dental Students in Saudi Arabia: A Cross-Sectional Study. (27034672)
2016
34
BruxApp: the ecological momentary assessment of awake bruxism. (27374364)
2016
35
Prosthodontic planning in patients with temporomandibular disorders and/or bruxism: A systematic review. (27836142)
2016
36
A Case of Bruxism-Induced Otalgia. (27626088)
2016
37
Five Things to Know About Sleep Bruxism. (27159944)
2016
38
Associations of sleep bruxism with age, sleep apnea and daytime problematic behaviors in children. (27087630)
2016
39
Bruxism in Movement Disorders: A Comprehensive Review. (27077925)
2016
40
Why not stop looking at bruxism as a black/white condition? Aetiology could be unrelated to clinical consequences. (27545318)
2016
41
Self-Reported bruxism and associated factors in Israeli adolescents. (26968152)
2016
42
Evaluation of a Proton Pump Inhibitor for Sleep Bruxism: A Randomized Clinical Trial. (27474257)
2016
43
Genetic polymorphisms in the serotonergic system are associated with circadian manifestations of bruxism. (27611726)
2016
44
Diagnostic accuracy of the use of parental-reported sleep bruxism in a polysomnographic study in children. (27612328)
2016
45
Diagnosis of sleep bruxism can assist in the detection of cases of verbal school bullying and measure the life satisfaction of adolescents. (27598528)
2016
46
Association between sleep bruxism and alcohol, caffeine, tobacco, and drug abuse: A systematic review. (27522154)
2016
47
Sleep Bruxism-Tooth Grinding Prevalence, Characteristics and Familial Aggregation: A Large Cross-Sectional Survey and Polysomnographic Validation. (27568807)
2016
48
Sleep bruxism in children: sleep studies correlate poorly with parental reports. (27198949)
2016
49
Association between possible sleep bruxism and sleep characteristics in children. (27691903)
2016
50
Evaluation of electromyographic signals in children with bruxism before and after therapy with Melissa Officinalis L-a randomized controlled clinical trial. (27134350)
2016

Variations for Bruxism

About this section

Expression for genes affiliated with Bruxism

About this section
Search GEO for disease gene expression data for Bruxism.

Pathways for genes affiliated with Bruxism

About this section

Pathways related to Bruxism according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3HTR2A, SLC6A4
29.0HTR2A, MECP2, SLC6A4

GO Terms for genes affiliated with Bruxism

About this section

Biological processes related to Bruxism according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1long-term memoryGO:000761610.5DRD2, MECP2
2neurological system process involved in regulation of systemic arterial blood pressureGO:000197610.5DRD2, MECP2
3protein localizationGO:000810410.5DRD2, MECP2
4startle responseGO:000196410.4DRD2, MECP2
5behavioral response to cocaineGO:004814810.3DRD2, HTR2A
6negative regulation of synaptic transmission, glutamatergicGO:005196710.3DRD2, HTR2A
7regulation of dopamine secretionGO:001405910.3DRD2, HTR2A
8release of sequestered calcium ion into cytosolGO:005120910.3DRD2, HTR2A
9synapse assemblyGO:000741610.3DRD2, MECP2
10sensory perception of painGO:001923310.2HTR2A, MECP2
11temperature homeostasisGO:000165910.1DRD2, HTR2A
12social behaviorGO:003517610.1MECP2, SLC6A4
13visual learningGO:00085429.8DRD2, MECP2
14response to hypoxiaGO:00016669.8DRD2, MECP2, SLC6A4
15memoryGO:00076139.7HTR2A, MECP2, SLC6A4
16response to drugGO:00424939.7DRD2, HTR2A, SLC6A4

Sources for Bruxism

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet