MCID: BRX001
MIFTS: 41

Bruxism malady

Oral diseases category

Summaries for Bruxism

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Wikipedia:63 Bruxism is the excessive grinding of the teeth and/or excessive clenching of the jaw. Bruxism is an oral... more...

MalaCards: Bruxism, also known as bruxism - teeth grinding, is related to rett syndrome and attention deficit hyperactivity disorder. An important gene associated with Bruxism is MECP2 (methyl CpG binding protein 2 (Rett syndrome)). Affiliated tissues include eye, bone and brain, and related mouse phenotype behavior/neurological.

Disease Ontology:8 A sleep disorder that involves involuntarily grinding or clenching of the teeth while sleeping.

Aliases & Classifications for Bruxism

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Sources:
8Disease Ontology, 44Novoseek, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Oral diseases


Aliases & Descriptions:

bruxism 8 44 60
bruxism - teeth grinding 8
sleep related bruxism 8
teeth grinding 8
grinding teeth 8


External Ids:

Disease Ontology8 DOID:2846
NCIt39 C73511
ICD9CM27 327.53

Related Diseases for Bruxism

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Bruxism:



Diseases related to bruxism

Clinical Features for Bruxism

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Drugs & Therapeutics for Bruxism

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Bruxism

Drug clinical trials:

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Search NIH Clinical Center for Bruxism

Search CenterWatch for Bruxism

Genetic Tests for Bruxism

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Anatomical Context for Bruxism

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Sources:
32MalaCards
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MalaCards organs/tissues related to Bruxism:

32
Eye, Bone, Brain, Heart, Kidney, Liver, Skin, Testes, Pineal

Animal Models for Bruxism or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Bruxism:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.4ADAM23, PCP2, MECP2, DRD2, KLF7

Publications for Bruxism

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Sources:
50PubMed
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Articles related to Bruxism:

(show top 50)    (show all 491)
idTitleAuthorsYear
1
Community based study of sleep bruxism during early childhood. (23219144)
2013
2
Prevalence of sleep bruxism in children: a systematic review of the literature. (23700983)
2013
3
Bruxism and myofascial TMDs. (23449896)
2013
4
Elements of implant-supported rehabilitation planning in patients with bruxism. (23172439)
2012
5
Association of genetic, psychological and behavioral factors with sleep bruxism in a Japanese population. (22545912)
2012
6
Buspirone for bruxism in a child with pervasive developmental disorder-not otherwise specified. (22136097)
2011
7
Letter to the editor, "influence of experimental acidification on sleep bruxism: a randomized trial". (21778355)
2011
8
Bruxism and prosthetic treatment: a critical review. (21596648)
2011
9
Clonidine has a paradoxical effect on cyclic arousal and sleep bruxism during NREM sleep. (21120152)
2010
10
Clinical significance of sleep bruxism on several occlusal and functional parameters. (21032978)
2010
11
Teeth Grinding: Is Emotional Stability related to Bruxism? (20835403)
2010
12
Bruxism after 3,4-methylenedioxymethamphetamine (ecstasy) abuse. (20515398)
2010
13
Management of temporomandibular disorder associated with bruxism. (19915278)
2009
14
Treatment of bruxism in individuals with developmental disabilities: a systematic review. (19181481)
2009
15
Is your knowledge up-to-date? Chronic periodontitis and bruxism. (19413551)
2009
16
Oro-facial activities in sleep bruxism patients and in normal subjects: a controlled polygraphic and audio-video study. (18976258)
2009
17
Bruxism and adenotonsillectomy. (18282616)
2008
18
Temporomandibular disorders and bruxism in childhood and adolescence: review of the literature. (18180045)
2008
19
Computer-based fabrication of occlusal splints for treatment of bruxism and TMD. (18477837)
2008
20
Perceived psychosocial job stress and sleep bruxism among male and female workers. (18474052)
2008
21
Principles for the management of bruxism. (18557917)
2008
22
Validation of the BiteStrip screener for sleep bruxism. (17618147)
2007
23
Bruxism in military pilots and non-pilots: tooth wear and psychological stress. (17310886)
2007
24
Sleep bruxism is associated to micro-arousals and an increase in cardiac sympathetic activity. (16911037)
2006
25
Reported bruxism and restless legs syndrome in media personnel with or without irregular shift work. (16134548)
2005
26
Perceived orofacial pain and its associations with reported bruxism and insomnia symptoms in media personnel with or without irregular shift work. (16040443)
2005
27
Effect of interocclusal appliance on masticatory performance of patients with bruxism. (16353466)
2005
28
Tiagabine may reduce bruxism and associated temporomandibular joint pain. (16252740)
2005
29
Rehabilitating a patient with bruxism-associated tooth tissue loss: a literature review and case report. (15061339)
2003
30
Changes in self-reported incidence of nocturnal bruxism in college students: 1966-2002. (14738339)
2003
31
Prevalence of bruxism in patients with different research diagnostic criteria for temporomandibular disorders (RDC/TMD) diagnoses. (14620701)
2003
32
Vectored upper cervical manipulation for chronic sleep bruxism, headache, and cervical spine pain in a child. (12902973)
2003
33
Familial nocturnal facio-mandibular myoclonus mimicking sleep bruxism. (11865148)
2002
34
Decreased amount of slow wave sleep in nocturnal bruxism is not improved by dental splint therapy. (11817263)
2001
35
Bruxism and the bite. (11494476)
2001
36
A bibliographical survey of bruxism with special emphasis on non-traditional treatment modalities. (11515601)
2001
37
Treating severe bruxism with botulinum toxin. (10680389)
2000
38
EEG checkerboard pattern of bruxism. (10489024)
1999
39
Bruxism in Rett syndrome: a case report. (10204460)
1999
40
Altered control of submaximal bite force during bruxism in humans. (10090631)
1999
41
Risperidol and withdrawal bruxism in Lewy body dementia. (9489584)
1998
42
Sleep bruxism is a disorder related to periodic arousals during sleep. (9539459)
1998
43
Cigarette smoking as a risk factor or an exacerbating factor for restless legs syndrome and sleep bruxism. (9231955)
1997
44
The effect of propranolol on sleep bruxism: hypothetical considerations based on a case study. (8924755)
1996
45
Bruxism threshold: an explanation for successful treatment of the multifactorial aetiology of bruxism. (9063132)
1995
46
Temporomandibular joint pain-dysfunction syndrome and bruxism: etiopathogenesis and treatment from a psychosomatic integrative viewpoint. (8332706)
1993
47
Effect of a full-arch maxillary occlusal splint on parafunctional activity during sleep in patients with nocturnal bruxism and signs and symptoms of craniomandibular disorders. (8445561)
1993
48
Permanent bruxism as a manifestation of the oculo-facial syndrome related to systemic Whipple's disease. (1372960)
1992
49
Tension headache and bruxism in the sleep disordered patient. (2073698)
1990
50
Reversible pulpitis with etiology of bruxism. (6955431)
1982

Genetic Variations for Bruxism

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Expression for genes affiliated with Bruxism

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Bruxism

Search GEO for disease gene expression data for Bruxism.

Pathways for genes affiliated with Bruxism

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Compounds for genes affiliated with Bruxism

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GO Terms for genes affiliated with Bruxism

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16Gene Ontology
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Biological processes related to Bruxism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neurological system process involved in regulation of systemic arterial blood pressureGO:0019769.9MECP2, DRD2
2long-term memoryGO:0076169.8MECP2, DRD2
3protein localizationGO:0081049.8MECP2, DRD2
4synapse assemblyGO:0074169.7DRD2, MECP2
5visual learningGO:0085429.5MECP2, DRD2

Products for genes affiliated with Bruxism

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  • Antibodies
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Sources for Bruxism

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet