MCID: BRX001
MIFTS: 41

Bruxism malady

Oral diseases category

Summaries for Bruxism

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Wikipedia:63 Bruxism is the excessive grinding of the teeth and/or excessive clenching of the jaw. Bruxism is an oral... more...

MalaCards: Bruxism, also known as bruxism - teeth grinding, is related to rett syndrome and attention deficit hyperactivity disorder. An important gene associated with Bruxism is MECP2 (methyl CpG binding protein 2 (Rett syndrome)). Affiliated tissues include eye, bone and brain, and related mouse phenotype behavior/neurological.

Disease Ontology:8 A sleep disorder that involves involuntarily grinding or clenching of the teeth while sleeping.

Aliases & Classifications for Bruxism

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Sources:
8Disease Ontology, 44Novoseek, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Oral diseases


Aliases & Descriptions:

bruxism 8 44 60
bruxism - teeth grinding 8
sleep related bruxism 8
teeth grinding 8
grinding teeth 8


External Ids:

Disease Ontology8 DOID:2846
NCIt39 C73511
ICD9CM27 327.53

Related Diseases for Bruxism

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Bruxism:



Diseases related to bruxism

Clinical Features for Bruxism

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Drugs & Therapeutics for Bruxism

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Bruxism

Drug clinical trials:

Search ClinicalTrials for Bruxism

Search NIH Clinical Center for Bruxism

Search CenterWatch for Bruxism

Genetic Tests for Bruxism

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Anatomical Context for Bruxism

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Sources:
32MalaCards
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MalaCards organs/tissues related to Bruxism:

32
Eye, Bone, Brain, Heart, Kidney, Liver, Skin, Testes, Pineal

Animal Models for Bruxism or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Bruxism:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.4ADAM23, PCP2, MECP2, DRD2, KLF7

Publications for Bruxism

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Sources:
50PubMed
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Articles related to Bruxism:

(show top 50)    (show all 491)
idTitleAuthorsYear
1
Suppression of sleep bruxism: effect of electrical stimulation of the masseter muscle triggered by heart rate elevation. (24392483)
2014
2
Legal psychoactive substances as risk factors for sleep-related bruxism: a nationwide Finnish Twin Cohort study. (23504639)
2013
3
Bruxism. Masticatory implications and anxiety. (24294819)
2013
4
Clinical management of implant prostheses in patients with bruxism. (22701484)
2012
5
Self-reported bruxism and temporomandibular disorders: findings from two specialised centres. (22251149)
2012
6
Is Bruxism a Risk Factor for Dental Implants? A Systematic Review of the Literature. (23151302)
2012
7
Awakening salivary cortisol levels of children with sleep bruxism. (22465270)
2012
8
Effects of sleep bruxism on functional and occlusal parameters: a prospective controlled investigation. (22935746)
2012
9
Are mental health problems and depression associated with bruxism in children? (22049927)
2012
10
Low-dose aripiprazole in the treatment of SSRI-induced bruxism. (23037677)
2012
11
Interaction of dental erosion and bruxism: the amplification of tooth wear. (21675679)
2011
12
Direct restorative treatment of dental erosion caused by gastroesophageal reflux disease associated with bruxism: a case report. (23738993)
2011
13
Association between sleep bruxism and stress sensitivity in an experimental psychological stress task. (22199130)
2011
14
A community study of sleep bruxism in Hong Kong children: association with comorbid sleep disorders and neurobehavioral consequences. (21684808)
2011
15
Arthrocentesis and stabilizing splint are the treatment of choice for acute intermittent closed lock in patients with bruxism. (20598897)
2011
16
Effectiveness of botulinum toxin type A treatment of neck pain related to nocturnal bruxism: a case report. (22027036)
2010
17
Venlafaxine-associated nocturnal bruxism in a depressive patient successfully treated with buspirone. (19264817)
2010
18
Topiramate for bruxism: report of 2 cases. (20473082)
2010
19
Evaluation of the relationship between anxiety and depression and bruxism. (19383250)
2009
20
Effect of an adjustable mandibular advancement appliance on sleep bruxism: a crossover sleep laboratory study. (19548407)
2009
21
Failure of tooth eruption in two patients with cerebral palsy and bruxism-a 10-year follow-up: a case report. (19573044)
2009
22
Treatment of bruxism in children: a systematic review. (19898717)
2009
23
Ambulatory polysomnography for the assessment of sleep bruxism. (18699968)
2008
24
Management of a child with autism and severe bruxism: a case report. (18603735)
2008
25
Four oral motor disorders: bruxism, dystonia, dyskinesia and drug-induced dystonic extrapyramidal reactions. (17185068)
2007
26
Occurrence of bruxism in a sample of Brazilian children with cerebral palsy. (17539224)
2007
27
Signs of bruxism and temporomandibular disorders among psychiatric patients. (17178495)
2007
28
Repair of porcelain crowns due to bruxism: a case report. (16895010)
2006
29
Bruxism secondary to brain injury treated with botulinum toxin-A: a case report. (17123443)
2006
30
Assessing bruxism. (16060467)
2005
31
A new analyzing method for quantification of abrasion on the Bruxcore device for sleep bruxism diagnosis. (16106717)
2005
32
Combating the adverse effects of bruxism in one visit. (14969000)
2004
33
The association between wear facets, bruxism, and severity of facial pain in patients with temporomandibular disorders. (12886214)
2003
34
Is bruxism severity a predictor of oral splint efficacy in patients with myofascial face pain? (12485379)
2003
35
Effect of occlusal splint and transcutaneous electric nerve stimulation on the signs and symptoms of temporomandibular disorders in patients with bruxism. (12366541)
2002
36
Sleep bruxism--new findings. (11360765)
2001
37
Bruxism in Huntington's disease. (10634263)
2000
38
Idiopathic myoclonus in the oromandibular region during sleep: a possible source of confusion in sleep bruxism diagnosis. (10495054)
1999
39
Motor activity in sleep bruxism with concomitant jaw muscle pain. A retrospective pilot study. (9085035)
1997
40
Do bruxism and temporomandibular disorders have a cause-and-effect relationship? (10332307)
1997
41
A new method for recording mandibular position during nocturnal bruxism. (8890063)
1996
42
Occlusal variables, bruxism and temporomandibular disorders: a clinical and kinesiographic assessment. (9217296)
1995
43
Understanding change: five-year follow-up of brief hypnotic treatment of chronic bruxism. (8203355)
1994
44
The effects of severe bruxism on sleep architecture: a preliminary report. (8500248)
1993
45
Bruxism and bruxomania. (1306911)
1992
46
Nocturnal bruxism and sleep stages. (1288574)
1992
47
Hypnotherapy in the treatment of the chronic nocturnal use of a dental splint prescribed for bruxism. (1894388)
1991
48
Treatment of root and alveolar bone resorption associated with bruxism. (2069830)
1991
49
Nocturnal bruxism and its clinical management. (1997355)
1991
50
Treatment of bruxism with botulinum toxin injections. (2380736)
1990

Genetic Variations for Bruxism

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Expression for genes affiliated with Bruxism

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Bruxism

Search GEO for disease gene expression data for Bruxism.

Pathways for genes affiliated with Bruxism

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Compounds for genes affiliated with Bruxism

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GO Terms for genes affiliated with Bruxism

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16Gene Ontology
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Biological processes related to Bruxism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neurological system process involved in regulation of systemic arterial blood pressureGO:0019769.9MECP2, DRD2
2long-term memoryGO:0076169.8MECP2, DRD2
3protein localizationGO:0081049.8MECP2, DRD2
4synapse assemblyGO:0074169.7DRD2, MECP2
5visual learningGO:0085429.5MECP2, DRD2

Products for genes affiliated with Bruxism

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  • Antibodies
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  • Antibodies

Sources for Bruxism

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet