MCID: BRX001
MIFTS: 39

Bruxism malady

Oral category

Summaries for Bruxism

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Wikipedia:64 Bruxism is the excessive grinding of the teeth and/or excessive clenching of the jaw. Bruxism is an oral... more...

MalaCards: Bruxism, also known as bruxism - teeth grinding, is related to rett syndrome and attention deficit hyperactivity disorder. An important gene associated with Bruxism is MECP2 (methyl CpG binding protein 2 (Rett syndrome)). Affiliated tissues include skin, liver and brain, and related mouse phenotype behavior/neurological.

Disease Ontology:8 A sleep disorder that involves involuntarily grinding or clenching of the teeth while sleeping.

Aliases & Classifications for Bruxism

Sources:
8Disease Ontology, 45Novoseek, 61UMLS, 35MeSH, 57SNOMED-CT, 40NCIt, 27ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Oral


Aliases & Descriptions:

bruxism 8 45 61
bruxism - teeth grinding 8
sleep related bruxism 8
teeth grinding 8
grinding teeth 8


External Ids:

Disease Ontology8 DOID:2846
NCIt40 C73511
ICD9CM27 327.53

Related Diseases for Bruxism

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Bruxism:



Diseases related to bruxism

Clinical Features for Bruxism

Drugs & Therapeutics for Bruxism

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Bruxism

Drug clinical trials:

Search ClinicalTrials for Bruxism

Search NIH Clinical Center for Bruxism

Search CenterWatch for Bruxism

Genetic Tests for Bruxism

Anatomical Context for Bruxism

Sources:
33MalaCards
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MalaCards organs/tissues related to Bruxism:

33
Skin, Liver, Brain, Kidney, Heart, Temporal lobe, Pineal

Animal Models for Bruxism or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Bruxism:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.4ADAM23, PCP2, MECP2, DRD2, KLF7

Publications for Bruxism

Sources:
51PubMed
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Articles related to Bruxism:

(show top 50)    (show all 491)
idTitleAuthorsYear
1
Polysomnographic analysis of bruxism. (24401352)
2014
2
Prospects for research and clinical medicine in sleep bruxism. (23643072)
2013
3
A relationship between bruxism and orofacial-dystonia? A trigeminal electrophysiological approach in a case report of pineal cavernoma. (24165294)
2013
4
Effect of contingent electrical stimulation on masticatory muscle activity and pain in patients with a myofascial temporomandibular disorder and sleep bruxism. (23424717)
2013
5
Bruxism and associated factors among Dutch adolescents. (23121154)
2013
6
Association among stress, personality traits, and sleep bruxism in children. (22583874)
2012
7
Sleep bruxism increases the risk for painful temporomandibular disorder, depression and non-specific physical symptoms. (22506562)
2012
8
The two main theories on dental bruxism. (22035706)
2012
9
Paroxetine-induced severe sleep bruxism successfully treated with buspirone. (22358247)
2012
10
Sleep bruxism and myofascial temporomandibular disorders: a laboratory-based polysomnographic investigation. (23115152)
2012
11
Prevalence of troublesome symptoms related to temporomandibular disorders and awareness of bruxism in 65- and 75-year-old subjects. (21916958)
2012
12
Aripiprazole-associated bruxism, akathisia, and parkinsonism in a bipolar patient. (21192162)
2011
13
Prevalence of bruxism awareness in Istanbul, Turkey. (20491234)
2010
14
Factors associated to bruxism in children from 4-6 years. (21271101)
2010
15
The relationship between sleep bruxism behavior and salivary stress biomarker level. (19260426)
2009
16
Orthodontics in a quantum world V: bruxism. (19438110)
2009
17
A significant increase in breathing amplitude precedes sleep bruxism. (18490400)
2008
18
Management of nocturnal bruxism with an anterior stop point appliance. (19248342)
2008
19
Management of bruxism-induced complications in removable partial denture wearers using specially designed dentures: a clinical report. (18290528)
2008
20
Occlusal splint for sleep bruxism: an electromyographic associated to Helkimo Index evaluation. (17987334)
2008
21
Genesis of sleep bruxism: motor and autonomic-cardiac interactions. (17313939)
2007
22
Prevalence of bruxism among Mexican children with Down syndrome. (17692187)
2007
23
Role of oral appliances in the management of sleep bruxism and temporomandibular disorders. (18051339)
2007
24
In vivo evaluation of noncarious cervical lesions in sleep bruxism subjects. (17692596)
2007
25
Bruxism and voluntary maximal bite force in young dentate adults. (16052788)
2005
26
Prevalence of bruxism in children receiving treatment for attention deficit hyperactivity disorder: a pilot study. (15554406)
2004
27
Reported bruxism and biopsychosocial symptoms: a longitudinal study. (15239782)
2004
28
Asymmetrical awake bruxism associated with multiple system atrophy. (15022196)
2004
29
Current knowledge on awake and sleep bruxism: overview. (12955779)
2003
30
Utility and validity of a new EMG-based bruxism detection system. (12956499)
2003
31
Hostility in TMD/bruxism patients and controls: a clinical comparison study and preliminary results. (12403186)
2002
32
Double-blind, crossover, placebo-controlled trial of bromocriptine in patients with sleep bruxism. (11391125)
2001
33
A piezoelectric film-based intrasplint detection method for bruxism. (11514809)
2001
34
Quantitative study of bite force during sleep associated bruxism. (11380790)
2001
35
Risk factors for sleep bruxism in the general population. (11157584)
2001
36
Influence of nocturnal bruxism on the stomatognathic system. Part I: a new device for measuring mandibular movements during sleep. (11737566)
2001
37
Treatment of bruxism and bruxomania (clinically tested). (10462946)
1999
38
Urinary catecholamine levels and bruxism in children. (10080306)
1999
39
Antidepressant-induced bruxism successfully treated with gabapentin. (10570590)
1999
40
Effects of the D2 receptor agonist bromocriptine on sleep bruxism: report of two single-patient clinical trials. (9294496)
1997
41
Various methods of achieving restoration of tooth structure loss due to bruxism. (9468839)
1996
42
Possible paroxetine-induced bruxism. (8913405)
1996
43
Occlusal adjustment and myoelectric activity of the jaw elevator muscles in patients with nocturnal bruxism and craniomandibular disorders. (8091124)
1994
44
Comparison of MMPI scores with self-report of sleep disturbance and bruxism in the facial pain population. (1302654)
1992
45
Arousability and bruxism in male and female college students. (1454478)
1992
46
Bruxism. (1755763)
1991
47
The social and psychologic factors of bruxism. (2056467)
1991
48
Suggestive hypnotherapy for nocturnal bruxism: a pilot study. (2024617)
1991
49
Bruxism. (2320262)
1990
50
Occurrence of temporomandibular disorder symptoms in healthy young adults with and without evidence of bruxism. (2098193)
1990

Genetic Variations for Bruxism

Expression for genes affiliated with Bruxism

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Bruxism

Search GEO for disease gene expression data for Bruxism.

Pathways for genes affiliated with Bruxism

Compounds for genes affiliated with Bruxism

GO Terms for genes affiliated with Bruxism

Sources:
16Gene Ontology
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Biological processes related to Bruxism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neurological system process involved in regulation of systemic arterial blood pressureGO:0019769.9MECP2, DRD2
2long-term memoryGO:0076169.8MECP2, DRD2
3protein localizationGO:0081049.8MECP2, DRD2
4synapse assemblyGO:0074169.7DRD2, MECP2
5visual learningGO:0085429.5MECP2, DRD2

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Sources for Bruxism

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet