MCID: BRX001
MIFTS: 46

Bruxism malady

Mental diseases, Oral diseases categories

Summaries for Bruxism

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9Disease Ontology, 66Wikipedia, 34MalaCards
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Wikipedia:66 Bruxism is the excessive grinding of the teeth and/or excessive clenching of the jaw. It is an oral... more...

MalaCards: Bruxism, also known as bruxism - teeth grinding, is related to attention deficit hyperactivity disorder and mental retardation. An important gene associated with Bruxism is MECP2 (methyl CpG binding protein 2 (Rett syndrome)). The compounds glutamate and gaba have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and bone, and related mouse phenotypes are adipose tissue and liver/biliary system.

Disease Ontology:9 A sleep disorder that involves involuntarily grinding or clenching of the teeth while sleeping.

Aliases & Classifications for Bruxism

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9Disease Ontology, 46Novoseek, 63UMLS, 36MeSH, 41NCIt, 59SNOMED-CT, 28ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Mental diseases, Oral diseases


Aliases & Descriptions:

bruxism 9 46 63
bruxism - teeth grinding 9
sleep related bruxism 9
grinding teeth 9
teeth grinding 9


External Ids:

Disease Ontology9 DOID:2846
NCIt41 C73511
ICD9CM28 327.53

Related Diseases for Bruxism

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Bruxism:



Diseases related to bruxism

Symptoms for Bruxism

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Drugs & Therapeutics for Bruxism

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Bruxism

Search CenterWatch for Bruxism

Genetic Tests for Bruxism

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Anatomical Context for Bruxism

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34MalaCards
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MalaCards organs/tissues related to Bruxism:

34
Eye, Brain, Bone, Heart, Skin, Liver, Kidney, Testes, Pineal

Animal Models for Bruxism or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Bruxism:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.3DRD2, MECP2
2MP:00053709.2DRD2, MECP2
3MP:00030129.2DRD2, MECP2
4MP:00053889.1MECP2, DRD2
5MP:00107719.1DRD2, MECP2
6MP:00053799.0DRD2, MECP2
7MP:00053908.8DRD2, MECP2

Publications for Bruxism

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53PubMed
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Articles related to Bruxism:

(show top 50)    (show all 489)
idTitleAuthorsYear
1
Treatment of bruxism with hydroxyzine: a possible mechanism of action. (23690201)
2013
2
Activation properties of trigeminal motoneurons in participants with and without bruxism. (24068753)
2013
3
Prospects for research and clinical medicine in sleep bruxism. (23643072)
2013
4
A relationship between bruxism and orofacial-dystonia? A trigeminal electrophysiological approach in a case report of pineal cavernoma. (24165294)
2013
5
Functional analysis and treatment of diurnal bruxism. (24114107)
2013
6
Evaluation of masticatory performance and bite force in children with sleep bruxism. (22758392)
2012
7
Genetic factors account for half of the phenotypic variance in liability to sleep-related bruxism in young adults: a nationwide Finnish twin cohort study. (22953759)
2012
8
Bruxism, temporomandibular dysfunction, tension-type headache, and migraine. (21762137)
2011
9
Buspirone for bruxism in a child with pervasive developmental disorder-not otherwise specified. (22136097)
2011
10
Self-reported bruxism - associations with perceived stress, motivation for control, dental anxiety and gagging. (20557433)
2011
11
Letter to the editor, "influence of experimental acidification on sleep bruxism: a randomized trial". (21778355)
2011
12
Interaction of dental erosion and bruxism: the amplification of tooth wear. (21675679)
2011
13
Effectiveness of botulinum toxin type A treatment of neck pain related to nocturnal bruxism: a case report. (22027036)
2010
14
Management of temporomandibular disorder associated with bruxism. (19915278)
2009
15
Bruxism arising during monotherapy with methylphenidate. (18928420)
2008
16
A significant increase in breathing amplitude precedes sleep bruxism. (18490400)
2008
17
The effectiveness of occlusal splints for sleep bruxism. (18364692)
2008
18
Bruxism in children with nasal obstruction. (18234357)
2008
19
Bruxism and autonomic activity. (17160590)
2007
20
Effects of an occlusal splint compared with cognitive-behavioral treatment on sleep bruxism activity. (17305711)
2007
21
Sleep bruxism: clinical aspects and characteristics in patients with and without chronic orofacial pain. (16448920)
2006
22
Mood psychopathology is possibly associated with bruxism. (17138432)
2006
23
Assessing bruxism. (16060467)
2005
24
Bruxism. Breaking the teeth-grinding habit. (16294388)
2005
25
Reported bruxism and restless legs syndrome in media personnel with or without irregular shift work. (16134548)
2005
26
A new analyzing method for quantification of abrasion on the Bruxcore device for sleep bruxism diagnosis. (16106717)
2005
27
Improvement of bruxism after T & A surgery. (15013611)
2004
28
Does tooth wear status predict ongoing sleep bruxism in 30-year-old Japanese subjects? (15008231)
2004
29
Topical review: sleep bruxism and the role of peripheral sensory influences. (14520766)
2003
30
Evidence that experimentally induced sleep bruxism is a consequence of transient arousal. (12651932)
2003
31
Rehabilitating a patient with bruxism-associated tooth tissue loss: a literature review and case report. (15061339)
2003
32
Association between sleep bruxism, swallowing-related laryngeal movement, and sleep positions. (12841373)
2003
33
Development of a portable bruxism monitoring and analysis device equipped with a microcomputer and its practical application. (12735429)
2002
34
Sleep bruxism related to obstructive sleep apnea: the effect of continuous positive airway pressure. (14592147)
2002
35
Decreased amount of slow wave sleep in nocturnal bruxism is not improved by dental splint therapy. (11817263)
2001
36
Variability in sleep bruxism activity over time. (11696077)
2001
37
Reports of SSRI-associated bruxism in the family physician's office. (12400402)
2001
38
Treating bruxism and clenching. (10770004)
2000
39
Managing bruxism and temporomandibular disorders using a centric relation occlusal device. (10650392)
1999
40
Effects of the D2 receptor agonist bromocriptine on sleep bruxism: report of two single-patient clinical trials. (9294496)
1997
41
An overview of bruxism and its management. (9142481)
1997
42
The effect of catecholamine precursor L-dopa on sleep bruxism: a controlled clinical trial. (8990057)
1997
43
Occlusal adjustment and myoelectric activity of the jaw elevator muscles in patients with nocturnal bruxism and craniomandibular disorders. (8091124)
1994
44
Bruxism secondary to chronic antidopaminergic drug exposure. (8104096)
1993
45
Chronic headache and nocturnal bruxism in a 5-year-old child treated with an occlusal splint. (8218118)
1993
46
Bruxism and bruxomania. (1306911)
1992
47
Hypnotherapy in the treatment of the chronic nocturnal use of a dental splint prescribed for bruxism. (1894388)
1991
48
Bruxism. (2320262)
1990
49
Treatment of bruxism with botulinum toxin injections. (2380736)
1990
50
The effects of an occlusal splint on the electromyographic activities of the temporal and masseter muscles during maximal clenching in patients with a habit of nocturnal bruxism and signs and symptoms of craniomandibular disorders. (2231163)
1990

Variations for Bruxism

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Expression for genes affiliated with Bruxism

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Bruxism

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Pathways for genes affiliated with Bruxism

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Compounds for genes affiliated with Bruxism

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46Novoseek
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Compounds related to Bruxism according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1glutamate469.1DRD2, MECP2
2gaba468.8DRD2, MECP2

GO Terms for genes affiliated with Bruxism

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17Gene Ontology
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Biological processes related to Bruxism according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neurological system process involved in regulation of systemic arterial blood pressureGO:0019769.2DRD2, MECP2
2long-term memoryGO:0076169.2DRD2, MECP2
3visual learningGO:0085429.1DRD2, MECP2
4response to hypoxiaGO:0016669.1DRD2, MECP2
5synapse assemblyGO:0074169.0MECP2, DRD2
6protein localizationGO:0081048.8DRD2, MECP2

Products for genes affiliated with Bruxism

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Sources for Bruxism

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet