MCID: BLM002
MIFTS: 49

Bulimia Nervosa malady

Mental diseases, Neuronal diseases categories

Aliases & Classifications for Bulimia Nervosa

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Aliases & Descriptions for Bulimia Nervosa:

Name: Bulimia Nervosa 8 44 61
Bulimia Nervosa, Susceptibility to 9
 
Binge Eating Disorder 61
Hyperorexia Nervosa 8


Classifications:



External Ids:

Disease Ontology8 DOID:12129
NCIt39 C34440
MeSH33 D002032
ICD1025 F50.2

Summaries for Bulimia Nervosa

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Disease Ontology:8 An eating disorder characterized by the restraining of food intake for a period of time followed by an over intake or binging period that results in feelings of guilt and low self-esteem.

MalaCards based summary: Bulimia Nervosa, also known as bulimia nervosa, susceptibility to, is related to eating disorder and obsessive-compulsive disorder. An important gene associated with Bulimia Nervosa is BDNF (brain-derived neurotrophic factor), and among its related pathways are Peptide hormone metabolism and Sympathetic Nerve Pathway (Neuroeffector Junction). The compounds sr 120819a and rimonabant have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and cortex, and related mouse phenotypes are endocrine/exocrine gland and digestive/alimentary.

Wikipedia:64 Bulimia nervosa is an eating disorder characterized by binge eating and purging, or consuming a large... more...

Related Diseases for Bulimia Nervosa

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Diseases related to Bulimia Nervosa via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 87)
idRelated DiseaseScoreTop Affiliating Genes
1eating disorder31.8GHRL, LEP, PYY
2obsessive-compulsive disorder30.9HTR1B, BDNF
3attention deficit-hyperactivity disorder30.9BDNF, HTR1B
4gastroesophageal reflux30.6PYY, CCK
5celiac disease30.4GHRL, CCK, PYY
6anorexia nervosa30.4PYY, LEP, BDNF, NPY, GHRL, CCK
7hypoglycemia30.3BDNF, NPY, GHRL
8obesity29.9PYY, LEP, MC4R, CCK, GHRL, NPY
9personality disorder10.7
10borderline personality disorder10.7
11blindness10.6
12bulimia nervosa, age of onset of weight loss in10.5
13cerebritis10.5
14duodenogastric reflux10.4CCK
15avoidant personality disorder10.4
16rectal prolapse10.4
17gastric dilatation10.4
18pathological gambling10.4
19esophagitis10.4
20substance dependence10.4
21gastroparesis10.2GHRL, CCK
22dyspepsia10.2CCK, GHRL
23glucagonoma10.2CCK, GHRL
24nutritional deficiency disease10.2LEP, GHRL
25gallbladder disease10.2PYY, CCK
26esophageal cancer10.2
27alcohol abuse10.2
28bipolar disorder10.2
29crohn's disease10.2
30antisocial personality disorder10.2
31premenstrual tension10.2
32tonsillitis10.2
33irritable bowel syndrome10.2
34hypokalemia10.2
35achalasia10.2
36hyperphosphatemia10.2
37kleptomania10.2
38graves' disease10.2
39compartment syndrome10.2
40pancreatitis10.2
41thyroiditis10.2
42cerebral atrophy10.2
43constipation10.2PYY, CCK
44short bowel syndrome10.2PYY, CCK
45anovulation10.2LEP, GHRL
46adrenal gland hyperfunction10.2LEP, GHRL
47psychotic disorder10.2CCK, BDNF
48growth hormone deficiency10.2GHRL, LEP
49medullary thyroid carcinoma, familial10.2GHRL, CCK
50hypopituitarism10.2LEP, GHRL

Graphical network of the top 20 diseases related to Bulimia Nervosa:



Diseases related to bulimia nervosa

Symptoms for Bulimia Nervosa

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Drugs & Therapeutics for Bulimia Nervosa

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Drug clinical trials:

Search ClinicalTrials for Bulimia Nervosa

Search NIH Clinical Center for Bulimia Nervosa

Genetic Tests for Bulimia Nervosa

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Anatomical Context for Bulimia Nervosa

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MalaCards organs/tissues related to Bulimia Nervosa:

31
Brain, Testes, Cortex, Heart, Thyroid, Adrenal gland, Tonsil, T cells, Prefrontal cortex, Cingulate cortex, Pituitary

Animal Models for Bulimia Nervosa or affiliated genes

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MGI Mouse Phenotypes related to Bulimia Nervosa:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.5GHRL, HTR1B, CCK, LEP
2MP:00053818.0LEP, GHRL, NPY, BDNF
3MP:00053757.9PYY, LEP, MC4R, GHRL, NPY
4MP:00028737.9PYY, MC4R, GHRL, NPY, BDNF
5MP:00053907.7PYY, LEP, MC4R, HTR1B, NPY
6MP:00053787.3PYY, LEP, MC4R, HTR1B, NPY, BDNF
7MP:00036317.3PYY, LEP, MC4R, CCK, NPY, BDNF
8MP:00053867.1BDNF, NPY, GHRL, HTR1B, MC4R, LEP
9MP:00053767.0PYY, LEP, MC4R, CCK, GHRL, NPY

Publications for Bulimia Nervosa

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Articles related to Bulimia Nervosa:

(show top 50)    (show all 606)
idTitleAuthorsYear
1
The emotional and attentional impact of exposure to one's own body in bulimia nervosa: a physiological view. (25036222)
2014
2
Comparing a 5-month trial of enhanced cognitive behavioural therapy to a 24-month trial of psychoanalytic psychotherapy for the treatment of bulimia nervosa. (25043436)
2014
3
Central coherence in adolescents with bulimia nervosa spectrum eating disorders. (25146149)
2014
4
Micronuclei and nuclear abnormalities in buccal mucosa cells in patients with anorexia and bulimia nervosa. (25232046)
2014
5
Facets of negative affect prior to and following binge-only, purge-only, and binge/purge events in women with bulimia nervosa. (22985015)
2013
6
Hard exercise, affect lability, and personality among individuals with bulimia nervosa. (24183126)
2013
7
The efficacy of a brief group CBT program in treating patients diagnosed with bulimia nervosa: a brief report. (23568413)
2013
8
Season of birth bias and bulimia nervosa--results from a multi-centre collaboration. (23338953)
2013
9
An fMRI investigation of emotional processing of body shape in bulimia nervosa. (21312206)
2012
10
Internalizing and externalizing behaviour problems in childhood contribute to the development of anorexia and bulimia nervosa-a study comparing sister pairs. (21826764)
2012
11
Negative affect and neural response to palatable food intake in bulimia nervosa. (22387716)
2012
12
Medical complications of bulimia nervosa and their treatments. (21312201)
2011
13
COMT Val158Met variant and functional haplotypes associated with childhood ADHD history in women with bulimia nervosa. (21300128)
2011
14
Ecological momentary assessment of bulimia nervosa: does dietary restriction predict binge eating? (21764036)
2011
15
An FMRI study of self-regulatory control and conflict resolution in adolescents with bulimia nervosa. (21676991)
2011
16
Aripiprazole in anorexia nervosa and low-weight bulimia nervosa: case reports. (20186719)
2011
17
College students' perceptions of individuals with anorexia and bulimia nervosa. (21472755)
2011
18
Weight suppression predicts time to remission from bulimia nervosa. (22004302)
2011
19
Overt and covert aggression in college women with bulimia nervosa. (22031013)
2011
20
Efficient prosthodontic treatment in a young patient with long-standing bulimia nervosa: A clinical report. (21723988)
2011
21
Changes of plasma obestatin, ghrelin and NPY in anorexia and bulimia nervosa patients before and after a high-carbohydrate breakfast. (20945961)
2011
22
Cognitive-behavioral therapy for subthreshold bulimia nervosa: A case series. (22290037)
2011
23
Personality pathology in purging disorder and bulimia nervosa. (21321987)
2011
24
The undue influence of shape and weight on self-evaluation in anorexia nervosa, bulimia nervosa and restrained eaters: a combined ERP and behavioral study. (20236572)
2011
25
Deliberate insulin underdosing and omission should be included in DSM-V criteria for bulimia nervosa. (20686152)
2010
26
Dialectical behaviour therapy and an added cognitive behavioural treatment module for eating disorders in women with borderline personality disorder and anorexia nervosa or bulimia nervosa who failed to respond to previous treatments. An open trial with a 15-month follow-up. (20444442)
2010
27
Mobile therapy: Use of text-messaging in the treatment of bulimia nervosa. (19718672)
2010
28
Quantitative evidence for distinct cognitive impairment in anorexia nervosa and bulimia nervosa. (19619407)
2010
29
Session and intersession experience related to treatment outcome in bulimia nervosa. (22402092)
2010
30
Correlation of BDNF blood levels with interoceptive awareness and maturity fears in anorexia and bulimia nervosa patients. (20195875)
2010
31
Cognitive-behavioural therapy for individuals with bulimia nervosa and a co-occurring substance use disorder. (19130465)
2009
32
Validity of the Eating Disorders Examination-Questionnaire when used with adolescents with bulimia nervosa and atypical bulimia nervosa. (20179414)
2009
33
Food cravings discriminate between anorexia and bulimia nervosa. Implications for "success" versus "failure" in dietary restriction. (19501754)
2009
34
Deficient activity in the neural systems that mediate self-regulatory control in bulimia nervosa. (19124688)
2009
35
Glucagon-like peptide-1 secretion in bulimia nervosa. (19631991)
2009
36
Bulimia nervosa and substance use disorder: similarities and differences. (18443981)
2008
37
Perceptual body image of patients with anorexia or bulimia nervosa and their fathers. (17384525)
2007
38
Esophageal cancer in a young woman with bulimia nervosa: a case report. (18047676)
2007
39
Daily and momentary mood and stress are associated with binge eating and vomiting in bulimia nervosa patients in the natural environment. (17663616)
2007
40
College students' mental models for recognizing anorexia and bulimia nervosa. (17241690)
2007
41
Anorexia nervosa patients with a prior history of bulimia nervosa. (17067877)
2006
42
Crohn's disease mimicking bulimia nervosa. (17235391)
2006
43
Affect regulation and food intake in bulimia nervosa: emotional responding to food cues after deprivation and subsequent eating. (16866597)
2006
44
The Iowa gambling task as a measure of decision making in women with bulimia nervosa. (16961954)
2006
45
Does personalized feedback improve the outcome of cognitive-behavioural guided self-care in bulimia nervosa? A preliminary randomized controlled trial. (16480570)
2006
46
Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. (15999344)
2005
47
Ilse, a patient with bulimia nervosa on integrative painting therapy. Bulimia nervosa. manifestation of avoiding conflicts? (17644870)
2002
48
Central dopaminergic function in anorexia and bulimia nervosa: a psychoneuroendocrine approach. (11259859)
2001
49
Lower serum activity of prolyl endopeptidase in anorexia and bulimia nervosa. (11070331)
2001
50
Ovarian morphology and insulin sensitivity in women with bulimia nervosa. (7586620)
1995

Variations for Bulimia Nervosa

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Expression for genes affiliated with Bulimia Nervosa

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Search GEO for disease gene expression data for Bulimia Nervosa.

Pathways for genes affiliated with Bulimia Nervosa

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Compounds for genes affiliated with Bulimia Nervosa

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Compounds related to Bulimia Nervosa according to GeneCards Suite gene sharing:

(show top 50)    (show all 130)
idCompoundScoreTop Affiliating Genes
1sr 120819a449.3PYY, NPY
2rimonabant44 28 1111.2CCK, GHRL, LEP
3[met]enkephalin449.2CCK, NPY
4[pro...34...]npy449.2PYY, NPY
5paroxetine44 50 28 1112.1BDNF, GHRL, HTR1B, LEP
6quetiapine44 50 28 24 1113.1LEP, HTR1B, GHRL, BDNF
7risperidone44 50 28 60 24 1114.1GHRL, BDNF, LEP, HTR1B
8octadecaneuropeptide449.1NPY, CCK, GHRL
9l-nmma449.0LEP, CCK, GHRL
10yohimbine44 1 28 1111.9HTR1B, NPY, PYY
11pramlintide44 119.9PYY, LEP, CCK, GHRL
12intralipid448.9LEP, CCK, GHRL, PYY
13incretin448.9CCK, PYY, NPY
14c-peptide448.8PYY, GHRL, CCK, LEP
15sibutramine44 119.8NPY, LEP, PYY
16enterostatin448.8LEP, NPY, CCK
17capsaicin44 289.7NPY, BDNF, LEP, GHRL
18tetrodotoxin44 60 2810.7PYY, NPY, BDNF, CCK
19naloxone44 28 50 1111.7CCK, GHRL, LEP
20octreotide44 60 28 1111.7NPY, GHRL, PYY, CCK
21atropine44 28 1110.7NPY, GHRL, CCK, PYY
22olanzapine44 50 28 24 1112.6BDNF, GHRL, HTR1B, MC4R, LEP
23clozapine44 28 50 1111.6GHRL, HTR1B, MC4R, BDNF, LEP
24haloperidol44 50 28 1 1112.6BDNF, MC4R, PYY, NPY
25opiate448.6GHRL, CCK, MC4R, NPY
26nifedipine44 28 50 1111.5GHRL, BDNF, NPY, LEP
27fenfluramine44 28 1110.5NPY, LEP, HTR1B, CCK
28alpha msh448.4LEP, MC4R, CCK, NPY
29carbachol44 28 1110.4BDNF, GHRL, CCK, PYY, NPY
305-hydroxytryptamine448.3PYY, HTR1B, NPY, GHRL, CCK
31histamine44 28 2410.3BDNF, CCK, GHRL, NPY, PYY
32cyclic amp44 249.2GHRL, PYY, NPY, BDNF, HTR1B
33gnrh448.2LEP, GHRL, NPY, BDNF, PYY
34amphetamine44 50 1110.2NPY, GHRL, PYY, MC4R, CCK
35epinephrine44 24 1110.2GHRL, BDNF, LEP, NPY
36corticosterone44 60 2410.2NPY, LEP, MC4R, GHRL, BDNF
37oxyntomodulin44 609.1CCK, GHRL, PYY, LEP, NPY
38orlistat44 60 1110.1NPY, LEP, CCK, GHRL, PYY
39adenylate448.1GHRL, CCK, NPY, BDNF, MC4R
40carbohydrates448.1PYY, NPY, GHRL, CCK, LEP
41cholesterol44 28 24 1111.0GHRL, CCK, BDNF, MC4R, LEP, PYY
42gaba447.8GHRL, LEP, PYY, BDNF, NPY, CCK
43norepinephrine44 24 119.8PYY, LEP, CCK, GHRL, NPY, BDNF
44testosterone44 60 24 1110.8BDNF, LEP, CCK, HTR1B, GHRL, NPY
45acetylcholine44 50 28 24 1111.8NPY, GHRL, LEP, PYY, BDNF, CCK
46arginine447.5PYY, LEP, MC4R, CCK, GHRL, NPY
47dopamine44 28 24 1110.5HTR1B, MC4R, PYY, GHRL, NPY, BDNF
48acth447.3NPY, BDNF, CCK, PYY, LEP, MC4R
49glucose447.2LEP, PYY, GHRL, BDNF, NPY, CCK
50cocaine44 117.9BDNF, LEP, MC4R, CCK, PYY, HTR1B

GO Terms for genes affiliated with Bulimia Nervosa

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Cellular components related to Bulimia Nervosa according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056157.7NPY, GHRL, CCK, LEP, PYY
2extracellular regionGO:00055767.0BDNF, PYY, LEP, CCK, GHRL, NPY

Biological processes related to Bulimia Nervosa according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1regulation of excitatory postsynaptic membrane potentialGO:006007910.0GHRL, BDNF
2positive regulation of synapse assemblyGO:005196510.0GHRL, BDNF
3dendrite developmentGO:00163589.9GHRL, BDNF
4response to hormoneGO:00097259.8GHRL, BDNF
5behavioral fear responseGO:00016629.8CCK, BDNF
6protein kinase C-activating G-protein coupled receptor signaling pathwayGO:00072059.7HTR1B, CCK
7negative regulation of appetiteGO:00320999.6CCK, LEP
8positive regulation of appetiteGO:00321009.6NPY, GHRL
9insulin secretionGO:00300739.5MC4R, LEP
10central nervous system neuron developmentGO:00219549.3LEP, NPY
11G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerGO:00071879.2NPY, HTR1B
12response to insulinGO:00328689.2MC4R, LEP
13eating behaviorGO:00427559.2PYY, LEP, CCK
14regulation of blood pressureGO:00082179.0NPY, LEP
15adult feeding behaviorGO:00083439.0NPY, GHRL, LEP
16digestionGO:00075868.9NPY, PYY
17feeding behaviorGO:00076318.6BDNF, NPY, MC4R, PYY

Molecular functions related to Bulimia Nervosa according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1G-protein coupled receptor bindingGO:00016649.3NPY, GHRL
2hormone activityGO:00051798.6CCK, LEP, PYY
3neuropeptide hormone activityGO:00051848.6NPY, CCK, PYY

Sources for Bulimia Nervosa

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet