MCID: BLM002
MIFTS: 59

Bulimia Nervosa malady

Mental diseases, Fetal diseases, Neuronal diseases categories
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Summaries for Bulimia Nervosa

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Disease Ontology:8 An eating disorder characterized by the restraining of food intake for a period of time followed by an over intake or binging period that results in feelings of guilt and low self-esteem.

MalaCards based summary: Bulimia Nervosa, also known as bulimia nervosa, susceptibility to, is related to eating disorder and obsessive-compulsive disorder. An important gene associated with Bulimia Nervosa is BULN (Bulimia nervosa, susceptibility to), and among its related pathways are Sympathetic Nerve Pathway (Neuroeffector Junction) and Peptide hormone metabolism. The compounds sr 120819a and [pro...34...]npy have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and cortex, and related mouse phenotypes are digestive/alimentary and adipose tissue.

Wikipedia:65 Bulimia nervosa is an eating disorder characterized by binge eating and purging, or consuming a large... more...

Aliases & Classifications for Bulimia Nervosa

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Sources:
8Disease Ontology, 9diseasecard, 46OMIM, 44Novoseek, 62UMLS, 57SNOMED-CT, 39NCIt, 34MeSH, 25ICD10
See all sources

Bulimia Nervosa, Aliases & Descriptions:

Name: Bulimia Nervosa 8 46 44 62
Bulimia Nervosa, Susceptibility to 9
 
Binge Eating Disorder 62
Hyperorexia Nervosa 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases
Anatomical: Mental diseases, Neuronal diseases


External Ids:

Disease Ontology8 DOID:12129
NCIt39 C34440
MeSH34 D002032
ICD1025 F50.2

Related Diseases for Bulimia Nervosa

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Diseases related to Bulimia Nervosa via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 88)
idRelated DiseaseScoreTop Affiliating Genes
1eating disorder31.6GHRL, LEP, PYY
2obsessive-compulsive disorder30.9BDNF, HTR1B
3attention deficit hyperactivity disorder30.9BDNF, HTR1B
4bipolar disorder30.7BDNF, NPY
5anorexia nervosa30.6LEP, NPY, CCK, PYY, BDNF, GHRL
6gastroesophageal reflux disease30.5CCK, PYY
7hypoglycemia30.4NPY, BDNF, GHRL
8celiac disease30.3CCK, GHRL, PYY
9obesity30.2NPY, PYY, CCK, LEP, GHRL
10personality disorder10.7
11borderline personality disorder10.6
12blindness10.6
13cerebritis10.5
14seasonal affective disorder10.4
15duodenogastric reflux10.4CCK
16avoidant personality disorder10.3
17rectal prolapse10.3
18pathological gambling10.3
19gastric dilatation10.3
20esophagitis10.3
21substance dependence10.3
22bulimia nervosa, age of onset of weight loss in10.3
23status epilepticus10.3BDNF, NPY
24double outlet right ventricle10.2GHRL, CCK
25crohn's disease10.2
26esophageal cancer10.2
27irritable bowel syndrome10.2
28premenstrual tension10.2
29hypokalemia10.2
30achalasia10.2
31hyperphosphatemia10.2
32kleptomania10.2
33graves' disease10.2
34antisocial personality disorder10.2
35tonsillitis10.2
36compartment syndrome10.2
37pancreatitis10.2
38thyroiditis10.2
39cerebral atrophy10.2
40gastroparesis10.2CCK, GHRL
41temporal lobe epilepsy10.2BDNF, NPY
42dyspepsia10.2CCK, GHRL
43glucagonoma10.2GHRL, CCK
44gallbladder disease10.2PYY, CCK
45short bowel syndrome10.1CCK, PYY
46constipation10.1CCK, PYY
47psychotic disorder10.1CCK, BDNF
48thyroid medullary carcinoma10.1CCK, GHRL
49neuroepithelioma10.1CCK, NPY
50huntington's disease10.1BDNF, NPY

Graphical network of the top 20 diseases related to Bulimia Nervosa:



Diseases related to bulimia nervosa

Symptoms for Bulimia Nervosa

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Drugs & Therapeutics for Bulimia Nervosa

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Drug clinical trials:

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Search NIH Clinical Center for Bulimia Nervosa

Genetic Tests for Bulimia Nervosa

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Anatomical Context for Bulimia Nervosa

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MalaCards organs/tissues related to Bulimia Nervosa:

32
Brain, Testes, Cortex, Eye, Heart, Thyroid, Adrenal gland, Tonsil, T cells, Prefrontal cortex, Cingulate cortex, Pituitary

Animal Models for Bulimia Nervosa or affiliated genes

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MGI Mouse Phenotypes related to Bulimia Nervosa:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.4LEP, GHRL, NPY, BDNF
2MP:00053758.3PYY, LEP, GHRL, NPY
3MP:00053798.1LEP, CCK, HTR1B, GHRL
4MP:00053907.9PYY, LEP, HTR1B, NPY
5MP:00053787.8BDNF, NPY, HTR1B, LEP, PYY
6MP:00036317.6BDNF, NPY, CCK, LEP, PYY
7MP:00053867.5BDNF, NPY, GHRL, HTR1B, LEP, PYY
8MP:00053767.3PYY, LEP, CCK, GHRL, NPY, BDNF

Publications for Bulimia Nervosa

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Articles related to Bulimia Nervosa:

(show top 50)    (show all 583)
idTitleAuthorsYear
1
The emotional and attentional impact of exposure to one's own body in bulimia nervosa: a physiological view. (25036222)
2014
2
Comparing a 5-month trial of enhanced cognitive behavioural therapy to a 24-month trial of psychoanalytic psychotherapy for the treatment of bulimia nervosa. (25043436)
2014
3
Central coherence in adolescents with bulimia nervosa spectrum eating disorders. (25146149)
2014
4
Micronuclei and nuclear abnormalities in buccal mucosa cells in patients with anorexia and bulimia nervosa. (25232046)
2014
5
Facets of negative affect prior to and following binge-only, purge-only, and binge/purge events in women with bulimia nervosa. (22985015)
2013
6
Hard exercise, affect lability, and personality among individuals with bulimia nervosa. (24183126)
2013
7
The efficacy of a brief group CBT program in treating patients diagnosed with bulimia nervosa: a brief report. (23568413)
2013
8
Season of birth bias and bulimia nervosa--results from a multi-centre collaboration. (23338953)
2013
9
An fMRI investigation of emotional processing of body shape in bulimia nervosa. (21312206)
2012
10
Internalizing and externalizing behaviour problems in childhood contribute to the development of anorexia and bulimia nervosa-a study comparing sister pairs. (21826764)
2012
11
Negative affect and neural response to palatable food intake in bulimia nervosa. (22387716)
2012
12
Medical complications of bulimia nervosa and their treatments. (21312201)
2011
13
COMT Val158Met variant and functional haplotypes associated with childhood ADHD history in women with bulimia nervosa. (21300128)
2011
14
Ecological momentary assessment of bulimia nervosa: does dietary restriction predict binge eating? (21764036)
2011
15
An FMRI study of self-regulatory control and conflict resolution in adolescents with bulimia nervosa. (21676991)
2011
16
Aripiprazole in anorexia nervosa and low-weight bulimia nervosa: case reports. (20186719)
2011
17
Weight suppression predicts time to remission from bulimia nervosa. (22004302)
2011
18
Overt and covert aggression in college women with bulimia nervosa. (22031013)
2011
19
Efficient prosthodontic treatment in a young patient with long-standing bulimia nervosa: A clinical report. (21723988)
2011
20
Changes of plasma obestatin, ghrelin and NPY in anorexia and bulimia nervosa patients before and after a high-carbohydrate breakfast. (20945961)
2011
21
Cognitive-behavioral therapy for subthreshold bulimia nervosa: A case series. (22290037)
2011
22
Personality pathology in purging disorder and bulimia nervosa. (21321987)
2011
23
The undue influence of shape and weight on self-evaluation in anorexia nervosa, bulimia nervosa and restrained eaters: a combined ERP and behavioral study. (20236572)
2011
24
Deliberate insulin underdosing and omission should be included in DSM-V criteria for bulimia nervosa. (20686152)
2010
25
Dialectical behaviour therapy and an added cognitive behavioural treatment module for eating disorders in women with borderline personality disorder and anorexia nervosa or bulimia nervosa who failed to respond to previous treatments. An open trial with a 15-month follow-up. (20444442)
2010
26
Mobile therapy: Use of text-messaging in the treatment of bulimia nervosa. (19718672)
2010
27
Quantitative evidence for distinct cognitive impairment in anorexia nervosa and bulimia nervosa. (19619407)
2010
28
Session and intersession experience related to treatment outcome in bulimia nervosa. (22402092)
2010
29
Correlation of BDNF blood levels with interoceptive awareness and maturity fears in anorexia and bulimia nervosa patients. (20195875)
2010
30
Cognitive-behavioural therapy for individuals with bulimia nervosa and a co-occurring substance use disorder. (19130465)
2009
31
Validity of the Eating Disorders Examination-Questionnaire when used with adolescents with bulimia nervosa and atypical bulimia nervosa. (20179414)
2009
32
Food cravings discriminate between anorexia and bulimia nervosa. Implications for "success" versus "failure" in dietary restriction. (19501754)
2009
33
Deficient activity in the neural systems that mediate self-regulatory control in bulimia nervosa. (19124688)
2009
34
Glucagon-like peptide-1 secretion in bulimia nervosa. (19631991)
2009
35
Bulimia nervosa and substance use disorder: similarities and differences. (18443981)
2008
36
Perceptual body image of patients with anorexia or bulimia nervosa and their fathers. (17384525)
2007
37
Esophageal cancer in a young woman with bulimia nervosa: a case report. (18047676)
2007
38
Daily and momentary mood and stress are associated with binge eating and vomiting in bulimia nervosa patients in the natural environment. (17663616)
2007
39
College students' mental models for recognizing anorexia and bulimia nervosa. (17241690)
2007
40
Anorexia nervosa patients with a prior history of bulimia nervosa. (17067877)
2006
41
Crohn's disease mimicking bulimia nervosa. (17235391)
2006
42
Affect regulation and food intake in bulimia nervosa: emotional responding to food cues after deprivation and subsequent eating. (16866597)
2006
43
The Iowa gambling task as a measure of decision making in women with bulimia nervosa. (16961954)
2006
44
Does personalized feedback improve the outcome of cognitive-behavioural guided self-care in bulimia nervosa? A preliminary randomized controlled trial. (16480570)
2006
45
Bulimia nervosa--a primary defect in the hypothalamic-pituitary-adrenal axis? (16499999)
2006
46
Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. (15999344)
2005
47
Ilse, a patient with bulimia nervosa on integrative painting therapy. Bulimia nervosa. manifestation of avoiding conflicts? (17644870)
2002
48
Central dopaminergic function in anorexia and bulimia nervosa: a psychoneuroendocrine approach. (11259859)
2001
49
Lower serum activity of prolyl endopeptidase in anorexia and bulimia nervosa. (11070331)
2001
50
Ovarian morphology and insulin sensitivity in women with bulimia nervosa. (7586620)
1995

Variations for Bulimia Nervosa

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Expression for genes affiliated with Bulimia Nervosa

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Expression patterns in normal tissues for genes affiliated with Bulimia Nervosa

Search GEO for disease gene expression data for Bulimia Nervosa.

Pathways for genes affiliated with Bulimia Nervosa

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Compounds for genes affiliated with Bulimia Nervosa

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Compounds related to Bulimia Nervosa according to GeneCards/GeneDecks:

(show top 50)    (show all 124)
idCompoundScoreTop Affiliating Genes
1sr 120819a449.6PYY, NPY
2[pro...34...]npy449.6PYY, NPY
3[met]enkephalin449.6CCK, NPY
4octadecaneuropeptide449.3GHRL, CCK, NPY
5yohimbine44 2 28 1112.2NPY, PYY, HTR1B
6incretin449.1PYY, CCK, NPY
7rimonabant44 28 1111.0CCK, LEP, GHRL
8sibutramine44 119.9NPY, LEP, PYY
9enterostatin448.9NPY, LEP, CCK
10alpha msh448.8NPY, CCK, LEP
11paroxetine44 50 28 1111.8HTR1B, LEP, BDNF, GHRL
12quetiapine44 50 28 24 1112.8HTR1B, LEP, BDNF, GHRL
13risperidone44 50 28 61 24 1113.8BDNF, GHRL, HTR1B, LEP
14tetrodotoxin44 61 2810.8PYY, BDNF, NPY, CCK
15amphetamine44 50 1110.8CCK, GHRL, NPY, PYY
16octreotide44 61 28 1111.8GHRL, CCK, PYY, NPY
17olanzapine44 50 28 24 1112.8GHRL, LEP, HTR1B, BDNF
18atropine44 28 1110.8GHRL, PYY, NPY, CCK
19capsaicin44 289.7LEP, GHRL, BDNF, NPY
20clozapine44 28 50 1111.7BDNF, LEP, HTR1B, GHRL
21naloxone44 28 50 1111.7GHRL, CCK, LEP
22corticosterone44 61 2410.7BDNF, NPY, GHRL, LEP
23nifedipine44 28 50 1111.6NPY, BDNF, GHRL, LEP
24l-nmma448.6CCK, GHRL, LEP
25clonidine44 50 28 1111.6LEP, NPY, PYY
26pramlintide44 119.5PYY, GHRL, CCK, LEP
27intralipid448.5GHRL, CCK, PYY, LEP
28epinephrine44 24 1110.5NPY, LEP, GHRL, BDNF
29fenfluramine44 28 1110.5LEP, CCK, HTR1B, NPY
30c-peptide448.5GHRL, CCK, LEP, PYY
31cyclic amp44 249.5NPY, PYY, HTR1B, BDNF, GHRL
32carbachol44 28 1110.5GHRL, CCK, PYY, NPY, BDNF
33histamine44 28 2410.4NPY, BDNF, PYY, GHRL, CCK
345-hydroxytryptamine448.4NPY, HTR1B, CCK, GHRL, PYY
35gnrh448.2LEP, GHRL, BDNF, NPY, PYY
36oxyntomodulin44 619.0CCK, NPY, GHRL, PYY, LEP
37orlistat44 61 1110.0LEP, GHRL, NPY, CCK, PYY
38carbohydrates448.0PYY, NPY, LEP, CCK, GHRL
39dopamine44 28 24 1111.0BDNF, HTR1B, GHRL, CCK, NPY, PYY
40cholesterol44 28 24 1111.0BDNF, PYY, LEP, CCK, GHRL
41arginine447.7PYY, LEP, CCK, GHRL, NPY
42testosterone44 61 24 1110.7CCK, LEP, HTR1B, GHRL, NPY, BDNF
43acth447.6NPY, BDNF, GHRL, LEP, CCK, PYY
44gaba447.6BDNF, NPY, GHRL, PYY, CCK, LEP
45norepinephrine44 24 119.6NPY, GHRL, CCK, LEP, PYY, BDNF
46acetylcholine44 50 28 24 1111.6GHRL, PYY, LEP, CCK, NPY, BDNF
47glucose447.5CCK, NPY, LEP, GHRL, BDNF, PYY
48tyrosine447.5NPY, GHRL, HTR1B, CCK, BDNF, PYY
49glutamate447.4LEP, CCK, BDNF, NPY, GHRL
50cocaine44 118.2GHRL, PYY, BDNF, NPY, LEP, CCK

GO Terms for genes affiliated with Bulimia Nervosa

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Cellular components related to Bulimia Nervosa according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056157.6NPY, GHRL, CCK, LEP, PYY
2extracellular regionGO:0055766.9BDNF, PYY, LEP, CCK, GHRL, NPY

Biological processes related to Bulimia Nervosa according to GeneCards/GeneDecks:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1regulation of excitatory postsynaptic membrane potentialGO:0600799.9GHRL, BDNF
2positive regulation of synapse assemblyGO:0519659.9GHRL, BDNF
3dendrite developmentGO:0163589.8BDNF, GHRL
4positive regulation of appetiteGO:0321009.8GHRL, NPY
5response to hormoneGO:0097259.7GHRL, BDNF
6behavioral fear responseGO:0016629.6CCK, BDNF
7protein kinase C-activating G-protein coupled receptor signaling pathwayGO:0072059.5HTR1B, CCK
8G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerGO:0071879.4NPY, HTR1B
9central nervous system neuron developmentGO:0219549.4NPY, LEP
10feeding behaviorGO:0076319.3BDNF, NPY, PYY
11negative regulation of appetiteGO:0320999.3CCK, LEP
12digestionGO:0075869.1NPY, PYY
13regulation of blood pressureGO:0082179.1NPY, LEP
14adult feeding behaviorGO:0083439.0NPY, GHRL, LEP
15eating behaviorGO:0427558.8PYY, LEP, CCK

Molecular functions related to Bulimia Nervosa according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1G-protein coupled receptor bindingGO:0016649.5NPY, GHRL
2neuropeptide hormone activityGO:0051848.7NPY, CCK, PYY
3hormone activityGO:0051798.2CCK, LEP, PYY

Products for genes affiliated with Bulimia Nervosa

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Sources for Bulimia Nervosa

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet