MCID: BLL012
MIFTS: 41

Bullous Impetigo malady

Skin diseases, Infectious diseases, Rare diseases categories
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Summaries for Bullous Impetigo

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Wikipedia:65 Bullous Impetigo is a cutaneous condition that characteristically occurs in the newborn, and is caused... more...

MalaCards based summary: Bullous Impetigo is related to impetigo and pemphigus, and has symptoms including chronic skin infection/ulcerations/ulcers/cancrum, erythema/erythematous lesions/erythroderma/polymorphous erythema and vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment. An important gene associated with Bullous Impetigo is DSG1 (desmoglein 1), and among its related pathways are Apoptotic cleavage of cellular proteins and Calcium signaling pathway. The compounds ivig and [125i]et-1 have been mentioned in the context of this disorder. Affiliated tissues include skin, and related mouse phenotypes are digestive/alimentary and craniofacial.

Aliases & Classifications for Bullous Impetigo

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Sources:
48Orphanet, 62UMLS, 26ICD10 via Orphanet, 63UMLS via Orphanet
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Bullous Impetigo, Aliases & Descriptions:

Name: Bullous Impetigo 48 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases, Rare diseases
Anatomical: Skin diseases


Characteristics (Orphanet epidemiological data):

48
bullous impetigo:
Inheritance: Sporadic; Age of onset: Variable; Age of death: Normal


External Ids:

ICD10 via Orphanet26 L01.0
UMLS via Orphanet63 C0021100

Related Diseases for Bullous Impetigo

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Graphical network of the top 20 diseases related to Bullous Impetigo:



Diseases related to bullous impetigo

Symptoms for Bullous Impetigo

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Symptoms:

48 (show all 7)
  • chronic skin infection/ulcerations/ulcers/cancrum
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • pustula/pustulosis
  • anomalies of the lymphatic system
  • renal glomerular defect/glomerulopathy
  • sepsis severe/septicemia

HPO human phenotypes related to Bullous Impetigo:

(show all 6)
id Description Frequency HPO Source Accession
1 abnormal blistering of the skin hallmark (90%) HP:0008066
2 pustule hallmark (90%) HP:0200039
3 skin ulcer hallmark (90%) HP:0200042
4 abnormality of the lymphatic system occasional (7.5%) HP:0100763
5 sepsis occasional (7.5%) HP:0100806
6 glomerulopathy occasional (7.5%) HP:0100820

Drugs & Therapeutics for Bullous Impetigo

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Drug clinical trials:

Search ClinicalTrials for Bullous Impetigo

Search NIH Clinical Center for Bullous Impetigo

Genetic Tests for Bullous Impetigo

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Anatomical Context for Bullous Impetigo

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MalaCards organs/tissues related to Bullous Impetigo:

32
Skin

Animal Models for Bullous Impetigo or affiliated genes

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MGI Mouse Phenotypes related to Bullous Impetigo:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5DSG3, EDNRA, EDNRB
2MP:00053828.2DSG3, EDNRA, EDNRB

Publications for Bullous Impetigo

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Articles related to Bullous Impetigo:

(show all 49)
idTitleAuthorsYear
1
Value of serum procalcitonin and interleukin-6 in patients with bullous impetigo and staphylococcal scalded skin syndrome. (25298068)
2014
2
Bullous impetigo. (24736928)
2014
3
Paediatric bullous dermatoses. Linear immunoglobulin A (IgA) dermatosis. Bullous impetigo. Bullous insect bite reaction. Neonatal Herpes simplex virus (HSV) infection. (23111154)
2013
4
Outbreak of bullous impetigo caused by Staphylococcus aureus strains of phage type 3C/71 in a maternity ward linked to nasal carriage of a healthcare worker. (22378195)
2012
5
The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward. (23168170)
2012
6
Bullous impetigo associated with Abiotrophia defectiva in an immunocompetent adult. (22493280)
2012
7
Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage. (21430094)
2011
8
Dermacase. Bullous impetigo. (18272632)
2008
9
Is blistering distal dactylitis a variant of bullous impetigo? (17362240)
2007
10
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. (17505275)
2007
11
Outbreak of staphylococcal bullous impetigo in a maternity ward linked to an asymptomatic healthcare worker. (17945394)
2007
12
Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. (17065642)
2006
13
Bullous impetigo of the face after epilation by threading. (16172329)
2005
14
Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo. (15688485)
2005
15
Generalized bullous impetigo in a neonate. (15575854)
2004
16
Desmosomes and disease: pemphigus and bullous impetigo. (15363804)
2004
17
Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in infants. (15482208)
2004
18
Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in skin lesions of bullous impetigo, atopic dermatitis and pemphigus foliaceus. (12653745)
2003
19
Clinicopathological case 3: pemphigus foliaceus; bullous impetigo; subcorneal pustular dermatoses. (12823325)
2003
20
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. (12093888)
2002
21
Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan. (11992289)
2002
22
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. (11062541)
2000
23
Bullous impetigo. (9369884)
1997
24
Vesicles and bulla in an infant. Bullous varicella (chicken pox complicated by bullous impetigo). (8285728)
1994
25
Bullous impetigo caused by group A streptococci. A case report. (1350146)
1992
26
Bullous impetigo in homosexual men--a risk marker for HIV-1 infection? (1607190)
1992
27
Is penicillin still the drug of choice for non-bullous impetigo? (1681172)
1991
28
Bullous impetigo and localized scalded skin syndrome in the elderly. (3623889)
1987
29
Antibiotic susceptibilities of Staphylococcus aureus strains derived from furuncle and bullous impetigo. (3894459)
1985
30
What histologic finding distinguishes superficial pemphigus and bullous impetigo? (6375421)
1984
31
Effects of serum albumin on coagulase release from Staphylococcus aureus derived from bullous impetigo. (6386912)
1984
32
Vacuoles in the upper part of the epidermis as a clue to eventuation of superficial pemphigus and bullous impetigo. (6731731)
1984
33
Epidemic bullous impetigo in a nursery due to a nasal carrier of Staphylococcus aureus: role of epidemiology and control measures. (6376403)
1984
34
Sequential bullous impetigo and cutaneous Herpes simplex virus infection. (6761658)
1982
35
Re-emergence of bullous impetigo. (6799136)
1982
36
Re-emergence of bullous impetigo. (6799044)
1981
37
Falsely normal direct immunofluorescent microscopic fundings in bullous impetigo. (7027964)
1981
38
Bullous impetigo caused by Streptococcus salivarius: a case report. (7002959)
1980
39
The epidermolytic toxin of Staphylococcus aureus: its failure to bind to cells and its detection in blister fluids of patients with bullous impetigo. (701847)
1978
40
Staphylococcal scalded skin syndrome. II. Serum level of anti exfoliatin and anti alpha-toxin in patients with staphylococcal scalded skin syndrome or bullous impetigo. (15461328)
1977
41
Bullous impetigo. Occurrence of localized scalded skin syndrome in an adult. (782365)
1976
42
Skin complications of heroin addiction. Bullous impetigo. (4513637)
1973
43
An epidemic of bullous impetigo arising from a central admission-observation nursery. (5059306)
1972
44
Bullous impetigo due to group II Staphylococcus aureus. An epidemic in a normal newborn nursery. (5422851)
1970
45
The etiology of poral closure. II. The role of staphylococcal infection in miliaria rubra and bullous impetigo. (15437052)
1950
46
The etiology of poral closure; an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. I. An historical review of the causation of miliaria. (15437051)
1950
47
Comments to "The etiology of poral closure, an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. By John P. O'Brien, M. D.". (15437055)
1950
48
An Outbreak of Bullous Impetigo Neonatorum. (20784840)
1943
49
The Prevention of Bullous Impetigo in Hospital Nurseries. (20322668)
1943

Variations for Bullous Impetigo

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Expression for genes affiliated with Bullous Impetigo

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Expression patterns in normal tissues for genes affiliated with Bullous Impetigo

Search GEO for disease gene expression data for Bullous Impetigo.

Pathways for genes affiliated with Bullous Impetigo

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Compounds for genes affiliated with Bullous Impetigo

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Compounds related to Bullous Impetigo according to GeneCards/GeneDecks:

(show all 30)
idCompoundScoreTop Affiliating Genes
1ivig449.6DSG1, DSG3
2[125i]et-1289.4EDNRB, EDNRA
3sitaxsentan44 2810.4EDNRA, EDNRB
4pd 145065449.4EDNRA, EDNRB
5bq610449.4EDNRB, EDNRA
6pd 142893449.4EDNRB, EDNRA
7bq 302044 2810.4EDNRB, EDNRA
8ambrisentan44 2810.4EDNRB, EDNRA
9sarafotoxin449.4EDNRB, EDNRA
10fr13931744 2810.4EDNRA, EDNRB
11irl 162044 2810.4EDNRA, EDNRB
12darusentan44 2810.4EDNRB, EDNRA
13tezosentan449.3EDNRB, EDNRA
14atrasentan449.3EDNRB, EDNRA
15bq78844 2810.3EDNRB, EDNRA
16bq12344 2810.3EDNRA, EDNRB
17bosentan44 1110.3EDNRA, EDNRB
18sulfonamide449.3EDNRB, EDNRA
19phosphoramidon44 1110.3EDNRA, EDNRB
20prednisolone44 28 1111.2DSG3, EDNRA
21losartan44 50 28 1112.2EDNRA, EDNRB
22agarose449.1EDNRA, EDNRB
23prostacyclin449.0EDNRB, EDNRA
24guanine44 24 1110.9EDNRA, EDNRB
25indomethacin44 28 61 1111.7EDNRA, EDNRB
26tyrosine448.5DSG3, EDNRA, EDNRB
27toxin a448.4DSG3, DSG1, EDNRA, EDNRB
28acetylcholine44 50 28 24 1112.4DSG3, DSG1, EDNRA, EDNRB
29serine448.2EDNRB, EDNRA, DSG1, DSG3
30calcium44 50 24 1111.2DSG3, DSG1, EDNRA, EDNRB

GO Terms for genes affiliated with Bullous Impetigo

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Cellular components related to Bullous Impetigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1desmosomeGO:0300579.3DSG3, DSG1
2nuclear membraneGO:0319659.0EDNRA, EDNRB
3plasma membraneGO:0058867.7DSG3, DSG1, EDNRA, EDNRB

Biological processes related to Bullous Impetigo according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1cellular component disassembly involved in execution phase of apoptosisGO:0069219.6DSG3, DSG1
2homophilic cell adhesionGO:0071569.4DSG3, DSG1
3regulation of epithelial cell proliferationGO:0506789.3EDNRA, EDNRB
4vasoconstrictionGO:0423109.2EDNRA, EDNRB
5enteric nervous system developmentGO:0484849.2EDNRB, EDNRA
6sensory perception of painGO:0192339.1EDNRA, EDNRB
7regulation of blood pressureGO:0082179.1EDNRB, EDNRA
8positive regulation of protein phosphorylationGO:0019349.0EDNRA, EDNRB
9positive regulation of cytosolic calcium ion concentrationGO:0072048.9EDNRA, EDNRB
10agingGO:0075688.7EDNRA, EDNRB

Molecular functions related to Bullous Impetigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endothelin receptor activityGO:0049629.0EDNRA, EDNRB

Products for genes affiliated with Bullous Impetigo

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  • Antibodies
  • Proteins
  • Lysates

Sources for Bullous Impetigo

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet