MCID: BLL012
MIFTS: 41

Bullous Impetigo malady

Skin diseases, Infectious diseases, Rare diseases categories

Summaries for Bullous Impetigo

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66Wikipedia, 34MalaCards
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Wikipedia:66 Bullous Impetigo is a cutaneous condition that characteristically occurs in the newborn, and is caused... more...

MalaCards: Bullous Impetigo is related to impetigo and pemphigus, and has symptoms including chronic skin infection/ulcerations/ulcers/cancrum, erythema/erythematous lesions/erythroderma/polymorphous erythema and vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment. An important gene associated with Bullous Impetigo is DSG1 (desmoglein 1), and among its related pathways are Apoptotic cleavage of cellular proteins and Calcium signaling pathway. The compounds ivig and [125i]et-1 have been mentioned in the context of this disorder. Affiliated tissues include skin, and related mouse phenotypes are digestive/alimentary and craniofacial.

Aliases & Classifications for Bullous Impetigo

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50Orphanet, 63UMLS, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases, Rare diseases
Anatomical: Skin diseases


Characteristics (Orphanet epidemiological data):

50
bullous impetigo:
Inheritance: Sporadic; Age of onset: Variable; Age of death: Normal


Aliases & Descriptions:

bullous impetigo 50 63


External Ids:

ICD10 via Orphanet27 L01.0
SNOMED-CT via Orphanet60 399183005
UMLS via Orphanet64 C0021100

Related Diseases for Bullous Impetigo

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Bullous Impetigo:



Diseases related to bullous impetigo

Symptoms for Bullous Impetigo

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50Orphanet
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Symptoms:

50 (show all 7)
  • chronic skin infection/ulcerations/ulcers/cancrum
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • pustula/pustulosis
  • anomalies of the lymphatic system
  • renal glomerular defect/glomerulopathy
  • sepsis severe/septicemia

Drugs & Therapeutics for Bullous Impetigo

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Bullous Impetigo

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Anatomical Context for Bullous Impetigo

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34MalaCards
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MalaCards organs/tissues related to Bullous Impetigo:

34
Skin

Animal Models for Bullous Impetigo or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Bullous Impetigo:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5DSG3, EDNRA, EDNRB
2MP:00053828.2DSG3, EDNRA, EDNRB

Publications for Bullous Impetigo

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53PubMed
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Articles related to Bullous Impetigo:

(show all 46)
idTitleAuthorsYear
1
Paediatric bullous dermatoses. Linear immunoglobulin A (IgA) dermatosis. Bullous impetigo. Bullous insect bite reaction. Neonatal Herpes simplex virus (HSV) infection. (23111154)
2013
2
Outbreak of bullous impetigo caused by Staphylococcus aureus strains of phage type 3C/71 in a maternity ward linked to nasal carriage of a healthcare worker. (22378195)
2012
3
The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward. (23168170)
2012
4
Bullous impetigo associated with Abiotrophia defectiva in an immunocompetent adult. (22493280)
2012
5
Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage. (21430094)
2011
6
Dermacase. Bullous impetigo. (18272632)
2008
7
Is blistering distal dactylitis a variant of bullous impetigo? (17362240)
2007
8
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. (17505275)
2007
9
Outbreak of staphylococcal bullous impetigo in a maternity ward linked to an asymptomatic healthcare worker. (17945394)
2007
10
Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. (17065642)
2006
11
Bullous impetigo of the face after epilation by threading. (16172329)
2005
12
Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo. (15688485)
2005
13
Generalized bullous impetigo in a neonate. (15575854)
2004
14
Desmosomes and disease: pemphigus and bullous impetigo. (15363804)
2004
15
Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in infants. (15482208)
2004
16
Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in skin lesions of bullous impetigo, atopic dermatitis and pemphigus foliaceus. (12653745)
2003
17
Clinicopathological case 3: pemphigus foliaceus; bullous impetigo; subcorneal pustular dermatoses. (12823325)
2003
18
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. (12093888)
2002
19
Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan. (11992289)
2002
20
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. (11062541)
2000
21
Bullous impetigo. (9369884)
1997
22
Vesicles and bulla in an infant. Bullous varicella (chicken pox complicated by bullous impetigo). (8285728)
1994
23
Bullous impetigo in homosexual men--a risk marker for HIV-1 infection? (1607190)
1992
24
Is penicillin still the drug of choice for non-bullous impetigo? (1681172)
1991
25
Bullous impetigo and localized scalded skin syndrome in the elderly. (3623889)
1987
26
Antibiotic susceptibilities of Staphylococcus aureus strains derived from furuncle and bullous impetigo. (3894459)
1985
27
What histologic finding distinguishes superficial pemphigus and bullous impetigo? (6375421)
1984
28
Effects of serum albumin on coagulase release from Staphylococcus aureus derived from bullous impetigo. (6386912)
1984
29
Vacuoles in the upper part of the epidermis as a clue to eventuation of superficial pemphigus and bullous impetigo. (6731731)
1984
30
Epidemic bullous impetigo in a nursery due to a nasal carrier of Staphylococcus aureus: role of epidemiology and control measures. (6376403)
1984
31
Sequential bullous impetigo and cutaneous Herpes simplex virus infection. (6761658)
1982
32
Re-emergence of bullous impetigo. (6799136)
1982
33
Re-emergence of bullous impetigo. (6799044)
1981
34
Falsely normal direct immunofluorescent microscopic fundings in bullous impetigo. (7027964)
1981
35
Bullous impetigo caused by Streptococcus salivarius: a case report. (7002959)
1980
36
The epidermolytic toxin of Staphylococcus aureus: its failure to bind to cells and its detection in blister fluids of patients with bullous impetigo. (701847)
1978
37
Staphylococcal scalded skin syndrome. II. Serum level of anti exfoliatin and anti alpha-toxin in patients with staphylococcal scalded skin syndrome or bullous impetigo. (15461328)
1977
38
Bullous impetigo. Occurrence of localized scalded skin syndrome in an adult. (782365)
1976
39
Skin complications of heroin addiction. Bullous impetigo. (4513637)
1973
40
An epidemic of bullous impetigo arising from a central admission-observation nursery. (5059306)
1972
41
Bullous impetigo due to group II Staphylococcus aureus. An epidemic in a normal newborn nursery. (5422851)
1970
42
The etiology of poral closure. II. The role of staphylococcal infection in miliaria rubra and bullous impetigo. (15437052)
1950
43
The etiology of poral closure; an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. I. An historical review of the causation of miliaria. (15437051)
1950
44
Comments to "The etiology of poral closure, an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. By John P. O'Brien, M. D.". (15437055)
1950
45
An Outbreak of Bullous Impetigo Neonatorum. (20784840)
1943
46
The Prevention of Bullous Impetigo in Hospital Nurseries. (20322668)
1943

Variations for Bullous Impetigo

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Expression for genes affiliated with Bullous Impetigo

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Bullous Impetigo

Search GEO for disease gene expression data for Bullous Impetigo.

Pathways for genes affiliated with Bullous Impetigo

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Sources:
51PathCards, 56Reactome, 39NCBI BioSystems Database, 31KEGG, 13EMD Millipore
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Compounds for genes affiliated with Bullous Impetigo

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46Novoseek, 30IUPHAR, 12DrugBank, 52PharmGKB, 25HMDB, 62Tocris Bioscience
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Compounds related to Bullous Impetigo according to GeneCards/GeneDecks:

(show all 30)
idCompoundScoreTop Affiliating Genes
1ivig469.6DSG1, DSG3
2[125i]et-1309.4EDNRB, EDNRA
3sitaxsentan46 3010.4EDNRA, EDNRB
4pd 145065469.4EDNRA, EDNRB
5bq610469.4EDNRB, EDNRA
6pd 142893469.4EDNRB, EDNRA
7bq 302046 3010.4EDNRB, EDNRA
8ambrisentan46 3010.4EDNRB, EDNRA
9sarafotoxin469.4EDNRB, EDNRA
10fr13931746 3010.4EDNRA, EDNRB
11irl 162046 3010.4EDNRA, EDNRB
12darusentan46 3010.4EDNRB, EDNRA
13tezosentan469.3EDNRB, EDNRA
14atrasentan469.3EDNRB, EDNRA
15bq78846 3010.3EDNRB, EDNRA
16bq12346 3010.3EDNRA, EDNRB
17bosentan46 1210.3EDNRA, EDNRB
18sulfonamide469.3EDNRB, EDNRA
19phosphoramidon46 1210.3EDNRA, EDNRB
20prednisolone46 30 1211.2DSG3, EDNRA
21losartan46 52 30 1212.2EDNRA, EDNRB
22agarose469.1EDNRA, EDNRB
23prostacyclin469.0EDNRB, EDNRA
24guanine46 25 1210.9EDNRA, EDNRB
25indomethacin46 30 62 1211.7EDNRA, EDNRB
26tyrosine468.5DSG3, EDNRA, EDNRB
27toxin a468.4DSG3, DSG1, EDNRA, EDNRB
28acetylcholine46 52 30 25 1212.4DSG3, DSG1, EDNRA, EDNRB
29serine468.2EDNRB, EDNRA, DSG1, DSG3
30calcium46 52 25 1211.2DSG3, DSG1, EDNRA, EDNRB

GO Terms for genes affiliated with Bullous Impetigo

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17Gene Ontology
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Cellular components related to Bullous Impetigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1desmosomeGO:0300579.3DSG3, DSG1
2nuclear membraneGO:0319659.0EDNRA, EDNRB
3plasma membraneGO:0058867.7DSG3, DSG1, EDNRA, EDNRB

Biological processes related to Bullous Impetigo according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1cellular component disassembly involved in execution phase of apoptosisGO:0069219.6DSG3, DSG1
2homophilic cell adhesionGO:0071569.4DSG3, DSG1
3regulation of epithelial cell proliferationGO:0506789.3EDNRA, EDNRB
4vasoconstrictionGO:0423109.2EDNRA, EDNRB
5enteric nervous system developmentGO:0484849.2EDNRB, EDNRA
6sensory perception of painGO:0192339.1EDNRA, EDNRB
7regulation of blood pressureGO:0082179.1EDNRB, EDNRA
8positive regulation of protein phosphorylationGO:0019349.0EDNRA, EDNRB
9positive regulation of cytosolic calcium ion concentrationGO:0072048.9EDNRA, EDNRB
10agingGO:0075688.7EDNRA, EDNRB

Molecular functions related to Bullous Impetigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endothelin receptor activityGO:0049629.0EDNRA, EDNRB

Products for genes affiliated with Bullous Impetigo

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Bullous Impetigo

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet