MCID: BLL012
MIFTS: 30

Bullous Impetigo malady

Skin diseases, Infectious diseases, Rare diseases categories

Aliases & Classifications for Bullous Impetigo

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Sources:
51Orphanet, 47Novoseek, 66UMLS via Orphanet, 28ICD10 via Orphanet
See all sources

Aliases & Descriptions for Bullous Impetigo:

Name: Bullous Impetigo 51 47


Classifications:



Characteristics (Orphanet epidemiological data):

51
bullous impetigo:
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy


External Ids:

Orphanet51 36237
UMLS via Orphanet66 C0021100
ICD10 via Orphanet28 L01.0

Summaries for Bullous Impetigo

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MalaCards based summary: Bullous Impetigo is related to impetigo and pemphigus, and has symptoms including abnormal blistering of the skin, pustule and skin ulcer. An important gene associated with Bullous Impetigo is DSG1 (Desmoglein 1), and among its related pathways are Calcium signaling pathway and Endothelins. Affiliated tissues include skin, and related mouse phenotypes are digestive/alimentary and craniofacial.

Related Diseases for Bullous Impetigo

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Graphical network of the top 20 diseases related to Bullous Impetigo:



Diseases related to bullous impetigo

Symptoms for Bullous Impetigo

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Symptoms:

 51 (show all 7)
  • chronic skin infection/ulcerations/ulcers/cancrum
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • pustula/pustulosis
  • anomalies of the lymphatic system
  • renal glomerular defect/glomerulopathy
  • sepsis severe/septicemia

HPO human phenotypes related to Bullous Impetigo:

(show all 6)
id Description Frequency HPO Source Accession
1 abnormal blistering of the skin hallmark (90%) HP:0008066
2 pustule hallmark (90%) HP:0200039
3 skin ulcer hallmark (90%) HP:0200042
4 abnormality of the lymphatic system occasional (7.5%) HP:0100763
5 sepsis occasional (7.5%) HP:0100806
6 glomerulopathy occasional (7.5%) HP:0100820

Drugs & Therapeutics for Bullous Impetigo

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Pharmacokinetics of Retapamulin in Pediatric Subjects With Uncomplicated Skin Infections.CompletedNCT00555061Phase 4
2Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With ImpetigoCompletedNCT01397461Phase 3
3Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With ImpetigoRecruitingNCT02090764Phase 3

Search NIH Clinical Center for Bullous Impetigo

Genetic Tests for Bullous Impetigo

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Anatomical Context for Bullous Impetigo

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MalaCards organs/tissues related to Bullous Impetigo:

33
Skin

Animal Models for Bullous Impetigo or affiliated genes

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MGI Mouse Phenotypes related to Bullous Impetigo:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.5DSG3, EDNRA, EDNRB
2MP:00053828.4DSG3, EDNRA, EDNRB

Publications for Bullous Impetigo

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Articles related to Bullous Impetigo:

(show all 48)
idTitleAuthorsYear
1
Value of serum procalcitonin and interleukin-6 in patients with bullous impetigo and staphylococcal scalded skin syndrome. (25298068)
2014
2
Bullous impetigo. (24736928)
2014
3
Outbreak of bullous impetigo caused by Staphylococcus aureus strains of phage type 3C/71 in a maternity ward linked to nasal carriage of a healthcare worker. (22378195)
2012
4
The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward. (23168170)
2012
5
Bullous impetigo associated with Abiotrophia defectiva in an immunocompetent adult. (22493280)
2012
6
Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage. (21430094)
2011
7
Dermacase. Bullous impetigo. (18272632)
2008
8
Is blistering distal dactylitis a variant of bullous impetigo? (17362240)
2007
9
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. (17505275)
2007
10
Outbreak of staphylococcal bullous impetigo in a maternity ward linked to an asymptomatic healthcare worker. (17945394)
2007
11
Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. (17065642)
2006
12
Bullous impetigo of the face after epilation by threading. (16172329)
2005
13
Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo. (15688485)
2005
14
Generalized bullous impetigo in a neonate. (15575854)
2004
15
Desmosomes and disease: pemphigus and bullous impetigo. (15363804)
2004
16
Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in infants. (15482208)
2004
17
Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in skin lesions of bullous impetigo, atopic dermatitis and pemphigus foliaceus. (12653745)
2003
18
Clinicopathological case 3: pemphigus foliaceus; bullous impetigo; subcorneal pustular dermatoses. (12823325)
2003
19
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. (12093888)
2002
20
Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan. (11992289)
2002
21
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. (11062541)
2000
22
Bullous impetigo. (9369884)
1997
23
Vesicles and bulla in an infant. Bullous varicella (chicken pox complicated by bullous impetigo). (8285728)
1994
24
Bullous impetigo caused by group A streptococci. A case report. (1350146)
1992
25
Bullous impetigo in homosexual men--a risk marker for HIV-1 infection? (1607190)
1992
26
Is penicillin still the drug of choice for non-bullous impetigo? (1681172)
1991
27
Bullous impetigo and localized scalded skin syndrome in the elderly. (3623889)
1987
28
Antibiotic susceptibilities of Staphylococcus aureus strains derived from furuncle and bullous impetigo. (3894459)
1985
29
What histologic finding distinguishes superficial pemphigus and bullous impetigo? (6375421)
1984
30
Effects of serum albumin on coagulase release from Staphylococcus aureus derived from bullous impetigo. (6386912)
1984
31
Vacuoles in the upper part of the epidermis as a clue to eventuation of superficial pemphigus and bullous impetigo. (6731731)
1984
32
Epidemic bullous impetigo in a nursery due to a nasal carrier of Staphylococcus aureus: role of epidemiology and control measures. (6376403)
1984
33
Sequential bullous impetigo and cutaneous Herpes simplex virus infection. (6761658)
1982
34
Re-emergence of bullous impetigo. (6799136)
1982
35
Re-emergence of bullous impetigo. (6799044)
1981
36
Falsely normal direct immunofluorescent microscopic fundings in bullous impetigo. (7027964)
1981
37
Bullous impetigo caused by Streptococcus salivarius: a case report. (7002959)
1980
38
The epidermolytic toxin of Staphylococcus aureus: its failure to bind to cells and its detection in blister fluids of patients with bullous impetigo. (701847)
1978
39
Staphylococcal scalded skin syndrome. II. Serum level of anti exfoliatin and anti alpha-toxin in patients with staphylococcal scalded skin syndrome or bullous impetigo. (15461328)
1977
40
Bullous impetigo. Occurrence of localized scalded skin syndrome in an adult. (782365)
1976
41
Skin complications of heroin addiction. Bullous impetigo. (4513637)
1973
42
An epidemic of bullous impetigo arising from a central admission-observation nursery. (5059306)
1972
43
Bullous impetigo due to group II Staphylococcus aureus. An epidemic in a normal newborn nursery. (5422851)
1970
44
The etiology of poral closure. II. The role of staphylococcal infection in miliaria rubra and bullous impetigo. (15437052)
1950
45
The etiology of poral closure; an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. I. An historical review of the causation of miliaria. (15437051)
1950
46
Comments to "The etiology of poral closure, an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. By John P. O'Brien, M. D.". (15437055)
1950
47
An Outbreak of Bullous Impetigo Neonatorum. (20784840)
1943
48
The Prevention of Bullous Impetigo in Hospital Nurseries. (20322668)
1943

Variations for Bullous Impetigo

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Expression for genes affiliated with Bullous Impetigo

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Search GEO for disease gene expression data for Bullous Impetigo.

Pathways for genes affiliated with Bullous Impetigo

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Pathways related to Bullous Impetigo according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.0EDNRA, EDNRB
29.0EDNRA, EDNRB
39.0EDNRA, EDNRB
49.0EDNRA, EDNRB

GO Terms for genes affiliated with Bullous Impetigo

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Cellular components related to Bullous Impetigo according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1desmosomeGO:00300579.4DSG1, DSG3

Biological processes related to Bullous Impetigo according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1endothelin receptor signaling pathwayGO:00861009.7EDNRA, EDNRB
2enteric nervous system developmentGO:00484849.5EDNRA, EDNRB
3cellular component disassembly involved in execution phase of apoptosisGO:00069219.5DSG1, DSG3
4vasoconstrictionGO:00423109.5EDNRA, EDNRB
5programmed cell deathGO:00125019.4DSG1, DSG3
6homophilic cell adhesion via plasma membrane adhesion moleculesGO:00071569.4DSG1, DSG3
7positive regulation of cytosolic calcium ion concentrationGO:00072049.2EDNRA, EDNRB
8regulation of blood pressureGO:00082179.2EDNRA, EDNRB

Molecular functions related to Bullous Impetigo according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endothelin receptor activityGO:00049629.0EDNRA, EDNRB

Sources for Bullous Impetigo

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet