MCID: BLL012
MIFTS: 38

Bullous Impetigo malady

Categories: Skin diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Bullous Impetigo

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Sources:
51Orphanet, 65UMLS, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Bullous Impetigo:

Name: Bullous Impetigo 51 65

Characteristics:

Orphanet epidemiological data:

51
bullous impetigo:
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Orphanet51 36237
ICD10 via Orphanet28 L01.0
UMLS via Orphanet66 C0021100
UMLS65 C0021100

Summaries for Bullous Impetigo

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Wikipedia:68 Bullous Impetigo is a cutaneous condition that characteristically occurs in the newborn, and is caused... more...

MalaCards based summary: Bullous Impetigo is related to impetigo and pemphigus, and has symptoms including abnormal blistering of the skin, pustule and skin ulcer. An important gene associated with Bullous Impetigo is DSG1 (Desmoglein 1), and among its related pathways are Prostaglandin Synthesis and Regulation and Endothelins. Affiliated tissues include skin, breast and liver, and related mouse phenotypes are digestive/alimentary and integument.

Related Diseases for Bullous Impetigo

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Diseases related to Bullous Impetigo via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
idRelated DiseaseScoreTop Affiliating Genes
1impetigo11.2
2pemphigus10.3
3intermediate dend syndrome10.2CALCA, IL6
4paresthesia10.2CALCA, IL6
5intellectual disability-sparse hair-brachydactyly syndrome10.2DSG1, DSG3
6pemphigus vulgaris10.2DSG1, DSG3
7peri-anal fistula10.1DSG1, DSG3
8tracheal stenosis10.1CALCA, IL6
9impetigo herpetiformis10.1DSG1, DSG3
10bartholin's duct cyst10.1DSG1, DSG3
11ichthyosis-hypotrichosis-sclerosing cholangitis syndrome10.1DSG1, DSG3
12miliaria rubra10.1
13miliaria10.1
14ovarian endometrioid cystadenoma10.1CALCA, IL6
15endometrial disease10.1DSG1, DSG3
16pemphigus foliaceus10.0
17herpes simplex10.0
18vestibule of mouth cancer10.0DSG1, DSG3
19cell type cancer10.0CALCA, IL6
20endometrial stromal sarcoma10.0DSG1, EDNRB
21hemifacial spasm9.9CALCA, EDNRA
22keratinizing squamous cell carcinoma9.9CALCA, IL6
23hiv-19.9
24toxic shock syndrome9.9
25dermatitis9.9
26atopic dermatitis9.9
27neonatal herpes9.9
28streptococcal toxic-shock syndrome9.9
29central hypoventilation syndrome, congenital9.9CALCA, EDNRB
30liver leiomyosarcoma9.8EDNRB, IL6
31liver lymphoma9.8EDNRA, EDNRB
32rh isoimmunization9.7DSG1, DSG3, IL6
33small intestine lymphoma9.7DSG1, DSG3
34medullary thyroid carcinoma, familial9.7CALCA, EDNRB
35albinism, oculocutaneous, type v9.5CALCA, EDNRA
36twin-to-twin transfusion syndrome9.5EDNRA, EDNRB
37leishmaniasis9.5DSG1, EDNRA, EDNRB
38cerebellar angioblastoma9.4EDNRA, EDNRB, IL6
39dermatitis herpetiformis9.1CALCA, DSG1, EDNRB, IL6
40acute opioid poisoning8.0CALCA, DSG1, DSG3, EDNRA, EDNRB, IL6

Graphical network of the top 20 diseases related to Bullous Impetigo:



Diseases related to bullous impetigo

Symptoms for Bullous Impetigo

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Symptoms:

 51 (show all 7)
  • chronic skin infection/ulcerations/ulcers/cancrum
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • pustula/pustulosis
  • anomalies of the lymphatic system
  • renal glomerular defect/glomerulopathy
  • sepsis severe/septicemia

HPO human phenotypes related to Bullous Impetigo:

(show all 6)
id Description Frequency HPO Source Accession
1 abnormal blistering of the skin hallmark (90%) HP:0008066
2 pustule hallmark (90%) HP:0200039
3 skin ulcer hallmark (90%) HP:0200042
4 abnormality of the lymphatic system occasional (7.5%) HP:0100763
5 sepsis occasional (7.5%) HP:0100806
6 glomerulopathy occasional (7.5%) HP:0100820

UMLS symptoms related to Bullous Impetigo:


coma blister, exanthema

Drugs & Therapeutics for Bullous Impetigo

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Pharmacokinetics of Retapamulin in Pediatric Subjects With Uncomplicated Skin Infections.CompletedNCT00555061Phase 4
2Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With ImpetigoCompletedNCT02090764Phase 3
3Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With ImpetigoCompletedNCT01397461Phase 3

Search NIH Clinical Center for Bullous Impetigo

Genetic Tests for Bullous Impetigo

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Anatomical Context for Bullous Impetigo

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MalaCards organs/tissues related to Bullous Impetigo:

33
Skin, Breast, Liver, Myeloid, B cells, Monocytes, T cells

Animal Models for Bullous Impetigo or affiliated genes

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MGI Mouse Phenotypes related to Bullous Impetigo:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.4DSG3, EDNRA, EDNRB, IL6
2MP:00107718.3DSG3, EDNRA, EDNRB, IL6
3MP:00053917.6DSG1, DSG3, EDNRA, EDNRB, IL6

Publications for Bullous Impetigo

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Articles related to Bullous Impetigo:

(show top 50)    (show all 51)
idTitleAuthorsYear
1
Case of bullous impetigo with enormous bulla developing into staphylococcal scalded skin syndrome. (26603272)
2016
2
Value of serum procalcitonin and interleukin-6 in patients with bullous impetigo and staphylococcal scalded skin syndrome. (25298068)
2014
3
Bullous impetigo. (24736928)
2014
4
Paediatric bullous dermatoses. Linear immunoglobulin A (IgA) dermatosis. Bullous impetigo. Bullous insect bite reaction. Neonatal Herpes simplex virus (HSV) infection. (23111154)
2013
5
Outbreak of bullous impetigo caused by Staphylococcus aureus strains of phage type 3C/71 in a maternity ward linked to nasal carriage of a healthcare worker. (22378195)
2012
6
The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward. (23168170)
2012
7
Bullous impetigo associated with Abiotrophia defectiva in an immunocompetent adult. (22493280)
2012
8
Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage. (21430094)
2011
9
Dermacase. Bullous impetigo. (18272632)
2008
10
Is blistering distal dactylitis a variant of bullous impetigo? (17362240)
2007
11
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. (17505275)
2007
12
Outbreak of staphylococcal bullous impetigo in a maternity ward linked to an asymptomatic healthcare worker. (17945394)
2007
13
Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. (17065642)
2006
14
Bullous impetigo of the face after epilation by threading. (16172329)
2005
15
Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo. (15688485)
2005
16
Generalized bullous impetigo in a neonate. (15575854)
2004
17
Desmosomes and disease: pemphigus and bullous impetigo. (15363804)
2004
18
Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in infants. (15482208)
2004
19
Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in skin lesions of bullous impetigo, atopic dermatitis and pemphigus foliaceus. (12653745)
2003
20
Clinicopathological case 3: pemphigus foliaceus; bullous impetigo; subcorneal pustular dermatoses. (12823325)
2003
21
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. (12093888)
2002
22
Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan. (11992289)
2002
23
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. (11062541)
2000
24
Bullous impetigo. (9369884)
1997
25
Vesicles and bulla in an infant. Bullous varicella (chicken pox complicated by bullous impetigo). (8285728)
1994
26
Bullous impetigo caused by group A streptococci. A case report. (1350146)
1992
27
Bullous impetigo in homosexual men--a risk marker for HIV-1 infection? (1607190)
1992
28
Is penicillin still the drug of choice for non-bullous impetigo? (1681172)
1991
29
Bullous impetigo and localized scalded skin syndrome in the elderly. (3623889)
1987
30
Antibiotic susceptibilities of Staphylococcus aureus strains derived from furuncle and bullous impetigo. (3894459)
1985
31
What histologic finding distinguishes superficial pemphigus and bullous impetigo? (6375421)
1984
32
Effects of serum albumin on coagulase release from Staphylococcus aureus derived from bullous impetigo. (6386912)
1984
33
Vacuoles in the upper part of the epidermis as a clue to eventuation of superficial pemphigus and bullous impetigo. (6731731)
1984
34
Epidemic bullous impetigo in a nursery due to a nasal carrier of Staphylococcus aureus: role of epidemiology and control measures. (6376403)
1984
35
Sequential bullous impetigo and cutaneous Herpes simplex virus infection. (6761658)
1982
36
Re-emergence of bullous impetigo. (6799136)
1982
37
Re-emergence of bullous impetigo. (6799044)
1981
38
Falsely normal direct immunofluorescent microscopic fundings in bullous impetigo. (7027964)
1981
39
Bullous impetigo caused by Streptococcus salivarius: a case report. (7002959)
1980
40
The epidermolytic toxin of Staphylococcus aureus: its failure to bind to cells and its detection in blister fluids of patients with bullous impetigo. (701847)
1978
41
Staphylococcal scalded skin syndrome. II. Serum level of anti exfoliatin and anti alpha-toxin in patients with staphylococcal scalded skin syndrome or bullous impetigo. (15461328)
1977
42
Bullous impetigo. Occurrence of localized scalded skin syndrome in an adult. (782365)
1976
43
Skin complications of heroin addiction. Bullous impetigo. (4513637)
1973
44
An epidemic of bullous impetigo arising from a central admission-observation nursery. (5059306)
1972
45
Bullous impetigo due to group II Staphylococcus aureus. An epidemic in a normal newborn nursery. (5422851)
1970
46
The etiology of poral closure. II. The role of staphylococcal infection in miliaria rubra and bullous impetigo. (15437052)
1950
47
The etiology of poral closure; an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. I. An historical review of the causation of miliaria. (15437051)
1950
48
Comments to "The etiology of poral closure, an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. By John P. O'Brien, M. D.". (15437055)
1950
49
An Outbreak of Bullous Impetigo Neonatorum. (20784840)
1943
50

Variations for Bullous Impetigo

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Expression for genes affiliated with Bullous Impetigo

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Search GEO for disease gene expression data for Bullous Impetigo.

Pathways for genes affiliated with Bullous Impetigo

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Pathways related to Bullous Impetigo according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5EDNRA, EDNRB
29.5EDNRA, EDNRB
39.0CALCA, IL6
48.9EDNRA, EDNRB, IL6
58.7CALCA, EDNRA, EDNRB

GO Terms for genes affiliated with Bullous Impetigo

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Biological processes related to Bullous Impetigo according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1endothelin receptor signaling pathwayGO:008610010.2EDNRA, EDNRB
2enteric nervous system developmentGO:004848410.1EDNRA, EDNRB
3vasoconstrictionGO:004231010.0EDNRA, EDNRB
4regulation of epithelial cell proliferationGO:005067810.0EDNRA, EDNRB
5regulation of blood pressureGO:00082179.9EDNRA, EDNRB
6positive regulation of cytosolic calcium ion concentrationGO:00072049.8EDNRA, EDNRB
7positive regulation of ERK1 and ERK2 cascadeGO:00703749.6EDNRA, IL6
8positive regulation of protein phosphorylationGO:00019349.6EDNRA, EDNRB
9sensory perception of painGO:00192339.6EDNRA, EDNRB
10response to yeastGO:00018789.4CALCA, IL6
11cellular response to lipopolysaccharideGO:00712229.4EDNRB, IL6
12defense response to Gram-negative bacteriumGO:00508299.3CALCA, IL6
13monocyte chemotaxisGO:00025489.2CALCA, IL6
14activation of adenylate cyclase activityGO:00071909.1CALCA, EDNRA
15response to organic cyclic compoundGO:00140709.0EDNRA, IL6
16cellular response to tumor necrosis factorGO:00713568.9CALCA, IL6
17agingGO:00075688.8CALCA, EDNRA, IL6

Sources for Bullous Impetigo

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet