MCID: BLL012
MIFTS: 35

Bullous Impetigo malady

Categories: Skin diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Bullous Impetigo

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Sources:
31ICD10 via Orphanet, 50Novoseek, 54Orphanet, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Bullous Impetigo:

Name: Bullous Impetigo 54 50 68

Characteristics:

Orphanet epidemiological data:

54
bullous impetigo:
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Orphanet54 ORPHA36237
UMLS via Orphanet69 C0021100
ICD10 via Orphanet31 L01.0

Summaries for Bullous Impetigo

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Wikipedia:71 Bullous Impetigo is a skin condition that characteristically occurs in the newborn, and is caused by a... more...

MalaCards based summary: Bullous Impetigo is related to impetigo and autosomal dominant cerebellar ataxia, and has symptoms including abnormal blistering of the skin, pustule and skin ulcer. An important gene associated with Bullous Impetigo is DSG1 (Desmoglein 1), and among its related pathways are Prostaglandin Synthesis and Regulation and Endothelins. Affiliated tissues include skin, and related mouse phenotypes are digestive/alimentary and integument.

Related Diseases for Bullous Impetigo

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Diseases related to Bullous Impetigo via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
idRelated DiseaseScoreTop Affiliating Genes
1impetigo11.6
2autosomal dominant cerebellar ataxia10.2EDNRA, IL6
3substernal goiter10.1CALCA, IL6
4sacrococcygeal dysgenesis association10.1DSG1, DSG3
5pemphigus10.1
6periodic paralyses10.1CALCA, IL6
7peripheral t-cell lymphoma10.1DSG1, DSG3
8gastric dilatation10.1CALCA, IL6
9skin amelanotic melanoma10.1DSG1, DSG3
10puerperal pulmonary embolism10.1DSG1, DSG3
11physical disorder10.0CALCA, IL6
12cirrhotic cardiomyopathy10.0DSG1, DSG3
13hereditary neuropathies10.0CALCA, EDNRA
14miliaria rubra10.0
15miliaria10.0
16subcorneal pustular dermatosis10.0DSG1, DSG3
17liver fibroma10.0DSG1, EDNRB
18diabetic macular edema9.9DSG1, DSG3
19pemphigus foliaceus9.9
20herpes simplex9.9
21lung occult small cell carcinoma9.9CALCA, IL6
22iga glomerulonephritis9.9EDNRA, EDNRB
23gum cancer9.9EDNRA, EDNRB
24central hypoventilation syndrome, congenital9.8CALCA, EDNRB
25multiple endocrine neoplasia iib9.8CALCA, EDNRB
26larynx carcinoma in situ9.8EDNRA, EDNRB
27hiv-19.7
28toxic shock syndrome9.7
29dermatitis9.7
30atopic dermatitis9.7
31neonatal herpes9.7
32streptococcal toxic-shock syndrome9.7
33rectum leiomyosarcoma9.7EDNRB, IL6
34perianal skin paget's disease9.7EDNRB, IL6
35small non-cleaved cell lymphoma9.6DSG1, DSG3
36lubani-al saleh-teebi syndrome9.5EDNRA, EDNRB
37medullary thyroid carcinoma, familial9.5CALCA, EDNRB
38meningococcal meningitis9.3CALCA, DSG1, DSG3, IL6
39bullous pemphigoid9.1CALCA, DSG1, EDNRB, IL6
40brain stem angioblastoma9.0CALCA, EDNRA, EDNRB, IL6

Graphical network of the top 20 diseases related to Bullous Impetigo:



Diseases related to bullous impetigo

Symptoms & Phenotypes for Bullous Impetigo

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Human phenotypes related to Bullous Impetigo:

 64 54 (show all 9)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormal blistering of the skin64 54 hallmark (90%) Very frequent (99-80%) HP:0008066
2 pustule64 54 hallmark (90%) Very frequent (99-80%) HP:0200039
3 skin ulcer64 hallmark (90%) HP:0200042
4 abnormality of the lymphatic system64 54 occasional (7.5%) Occasional (29-5%) HP:0100763
5 sepsis64 54 occasional (7.5%) Occasional (29-5%) HP:0100806
6 glomerulopathy64 54 occasional (7.5%) Occasional (29-5%) HP:0100820
7 septic arthritis54 Occasional (29-5%)
8 recurrent bacterial skin infections54 Very frequent (99-80%)
9 erythema54 Very frequent (99-80%)

UMLS symptoms related to Bullous Impetigo:


exanthema, coma blister

MGI Mouse Phenotypes related to Bullous Impetigo according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.2DSG3, EDNRA, EDNRB, IL6
2MP:00107719.1DSG3, EDNRA, EDNRB, IL6
3MP:00053889.1DSG3, EDNRA, EDNRB, IL6
4MP:00053908.7DSG1, DSG3, EDNRA, EDNRB, IL6
5MP:00053917.9DSG1, DSG3, EDNRA, EDNRB, IL6

Drugs & Therapeutics for Bullous Impetigo

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Pharmacokinetics of Retapamulin in Pediatric Subjects With Uncomplicated Skin Infections.CompletedNCT00555061Phase 4
2Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With ImpetigoCompletedNCT02090764Phase 3
3Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With ImpetigoCompletedNCT01397461Phase 3

Search NIH Clinical Center for Bullous Impetigo

Genetic Tests for Bullous Impetigo

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Anatomical Context for Bullous Impetigo

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MalaCards organs/tissues related to Bullous Impetigo:

36
Skin

Publications for Bullous Impetigo

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Articles related to Bullous Impetigo:

(show top 50)    (show all 53)
idTitleAuthorsYear
1
Staphylococcal bullous impetigo in a neonate. (27458596)
2016
2
Case of bullous impetigo with enormous bulla developing into staphylococcal scalded skin syndrome. (26603272)
2016
3
Bullous impetigo and pregnancy: Case report and review of blistering conditions in pregnancy. (27617460)
2016
4
Bullous Impetigo Rapid Diagnostic and Therapeutic Quiz: A Model for Assessing Basic Dermatology Knowledge of Primary Care Providers. (27599660)
2016
5
Bullous impetigo. (24736928)
2014
6
Value of serum procalcitonin and interleukin-6 in patients with bullous impetigo and staphylococcal scalded skin syndrome. (25298068)
2014
7
Paediatric bullous dermatoses. Linear immunoglobulin A (IgA) dermatosis. Bullous impetigo. Bullous insect bite reaction. Neonatal Herpes simplex virus (HSV) infection. (23111154)
2013
8
Outbreak of bullous impetigo caused by Staphylococcus aureus strains of phage type 3C/71 in a maternity ward linked to nasal carriage of a healthcare worker. (22378195)
2012
9
Bullous impetigo associated with Abiotrophia defectiva in an immunocompetent adult. (22493280)
2012
10
The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward. (23168170)
2012
11
Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage. (21430094)
2011
12
Dermacase. Bullous impetigo. (18272632)
2008
13
Is blistering distal dactylitis a variant of bullous impetigo? (17362240)
2007
14
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. (17505275)
2007
15
Outbreak of staphylococcal bullous impetigo in a maternity ward linked to an asymptomatic healthcare worker. (17945394)
2007
16
Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. (17065642)
2006
17
Bullous impetigo of the face after epilation by threading. (16172329)
2005
18
Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo. (15688485)
2005
19
Generalized bullous impetigo in a neonate. (15575854)
2004
20
Desmosomes and disease: pemphigus and bullous impetigo. (15363804)
2004
21
Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in infants. (15482208)
2004
22
Clinicopathological case 3: pemphigus foliaceus; bullous impetigo; subcorneal pustular dermatoses. (12823325)
2003
23
Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in skin lesions of bullous impetigo, atopic dermatitis and pemphigus foliaceus. (12653745)
2003
24
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. (12093888)
2002
25
Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan. (11992289)
2002
26
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. (11062541)
2000
27
Bullous impetigo. (9369884)
1997
28
Vesicles and bulla in an infant. Bullous varicella (chicken pox complicated by bullous impetigo). (8285728)
1994
29
Bullous impetigo caused by group A streptococci. A case report. (1350146)
1992
30
Bullous impetigo in homosexual men--a risk marker for HIV-1 infection? (1607190)
1992
31
Is penicillin still the drug of choice for non-bullous impetigo? (1681172)
1991
32
Bullous impetigo and localized scalded skin syndrome in the elderly. (3623889)
1987
33
Antibiotic susceptibilities of Staphylococcus aureus strains derived from furuncle and bullous impetigo. (3894459)
1985
34
What histologic finding distinguishes superficial pemphigus and bullous impetigo? (6375421)
1984
35
Effects of serum albumin on coagulase release from Staphylococcus aureus derived from bullous impetigo. (6386912)
1984
36
Epidemic bullous impetigo in a nursery due to a nasal carrier of Staphylococcus aureus: role of epidemiology and control measures. (6376403)
1984
37
Vacuoles in the upper part of the epidermis as a clue to eventuation of superficial pemphigus and bullous impetigo. (6731731)
1984
38
Sequential bullous impetigo and cutaneous Herpes simplex virus infection. (6761658)
1982
39
Re-emergence of bullous impetigo. (6799136)
1982
40
Falsely normal direct immunofluorescent microscopic fundings in bullous impetigo. (7027964)
1981
41
Re-emergence of bullous impetigo. (6799044)
1981
42
Bullous impetigo caused by Streptococcus salivarius: a case report. (7002959)
1980
43
The epidermolytic toxin of Staphylococcus aureus: its failure to bind to cells and its detection in blister fluids of patients with bullous impetigo. (701847)
1978
44
Staphylococcal scalded skin syndrome. II. Serum level of anti exfoliatin and anti alpha-toxin in patients with staphylococcal scalded skin syndrome or bullous impetigo. (15461328)
1977
45
Bullous impetigo. Occurrence of localized scalded skin syndrome in an adult. (782365)
1976
46
Skin complications of heroin addiction. Bullous impetigo. (4513637)
1973
47
An epidemic of bullous impetigo arising from a central admission-observation nursery. (5059306)
1972
48
Bullous impetigo due to group II Staphylococcus aureus. An epidemic in a normal newborn nursery. (5422851)
1970
49
Comments to "The etiology of poral closure, an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. By John P. O'Brien, M. D.". (15437055)
1950
50
The etiology of poral closure. II. The role of staphylococcal infection in miliaria rubra and bullous impetigo. (15437052)
1950

Variations for Bullous Impetigo

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Expression for genes affiliated with Bullous Impetigo

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Search GEO for disease gene expression data for Bullous Impetigo.

Pathways for genes affiliated with Bullous Impetigo

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Pathways related to Bullous Impetigo according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5EDNRA, EDNRB
29.5EDNRA, EDNRB
39.0CALCA, IL6
48.9EDNRA, EDNRB, IL6
58.7CALCA, EDNRA, EDNRB

GO Terms for genes affiliated with Bullous Impetigo

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Cellular components related to Bullous Impetigo according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1desmosomeGO:00300579.5DSG1, DSG3

Biological processes related to Bullous Impetigo according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1endothelin receptor signaling pathwayGO:008610010.2EDNRA, EDNRB
2enteric nervous system developmentGO:004848410.2EDNRA, EDNRB
3regulation of blood pressureGO:000821710.1EDNRA, EDNRB
4regulation of epithelial cell proliferationGO:005067810.1EDNRA, EDNRB
5sensory perception of painGO:00192339.9EDNRA, EDNRB
6activation of adenylate cyclase activityGO:00071909.9CALCA, EDNRA
7vasoconstrictionGO:00423109.8EDNRA, EDNRB
8positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathwayGO:00514829.8CALCA, EDNRA
9cellular response to tumor necrosis factorGO:00713569.8CALCA, IL6
10monocyte chemotaxisGO:00025489.8CALCA, IL6
11response to painGO:00482659.7CALCA, EDNRB
12response to heatGO:00094089.7CALCA, IL6
13negative regulation of apoptotic processGO:00430669.6EDNRA, EDNRB, IL6
14positive regulation of cell proliferationGO:00082849.5EDNRA, EDNRB, IL6
15response to lipopolysaccharideGO:00324969.4EDNRA, EDNRB, IL6
16positive regulation of cytosolic calcium ion concentrationGO:00072049.3CALCA, EDNRA, EDNRB
17vasodilationGO:00423119.2CALCA, EDNRB
18agingGO:00075688.8CALCA, EDNRA, EDNRB, IL6

Molecular functions related to Bullous Impetigo according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endothelin receptor activityGO:00049629.5EDNRA, EDNRB

Sources for Bullous Impetigo

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet