MCID: BLL012
MIFTS: 32

Bullous Impetigo malady

Categories: Skin diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Bullous Impetigo

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Sources:
51Orphanet, 65UMLS, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Bullous Impetigo:

Name: Bullous Impetigo 51 65

Characteristics:

Orphanet epidemiological data:

51
bullous impetigo:
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Orphanet51 36237
ICD10 via Orphanet28 L01.0
UMLS via Orphanet66 C0021100
UMLS65 C0021100

Summaries for Bullous Impetigo

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Wikipedia:68 Bullous Impetigo is a cutaneous condition that characteristically occurs in the newborn, and is caused... more...

MalaCards based summary: Bullous Impetigo is related to impetigo and breast cancer, and has symptoms including abnormal blistering of the skin, pustule and skin ulcer. An important gene associated with Bullous Impetigo is DSG1 (Desmoglein 1), and among its related pathways are Prostaglandin Synthesis and Regulation and Endothelins. Affiliated tissues include skin, brain and breast, and related mouse phenotypes are digestive/alimentary and integument.

Related Diseases for Bullous Impetigo

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Graphical network of the top 20 diseases related to Bullous Impetigo:



Diseases related to bullous impetigo

Symptoms for Bullous Impetigo

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Symptoms:

 51 (show all 7)
  • chronic skin infection/ulcerations/ulcers/cancrum
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • pustula/pustulosis
  • anomalies of the lymphatic system
  • renal glomerular defect/glomerulopathy
  • sepsis severe/septicemia

HPO human phenotypes related to Bullous Impetigo:

(show all 6)
id Description Frequency HPO Source Accession
1 abnormal blistering of the skin hallmark (90%) HP:0008066
2 pustule hallmark (90%) HP:0200039
3 skin ulcer hallmark (90%) HP:0200042
4 abnormality of the lymphatic system occasional (7.5%) HP:0100763
5 sepsis occasional (7.5%) HP:0100806
6 glomerulopathy occasional (7.5%) HP:0100820

Drugs & Therapeutics for Bullous Impetigo

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Pharmacokinetics of Retapamulin in Pediatric Subjects With Uncomplicated Skin Infections.CompletedNCT00555061Phase 4
2Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With ImpetigoCompletedNCT02090764Phase 3
3Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With ImpetigoCompletedNCT01397461Phase 3

Search NIH Clinical Center for Bullous Impetigo

Genetic Tests for Bullous Impetigo

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Anatomical Context for Bullous Impetigo

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MalaCards organs/tissues related to Bullous Impetigo:

33
Skin, Brain, Breast, Ovary, Monocytes, B cells, T cells

Animal Models for Bullous Impetigo or affiliated genes

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MGI Mouse Phenotypes related to Bullous Impetigo:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.4DSG3, EDNRA, EDNRB, IL6
2MP:00107718.3DSG3, EDNRA, EDNRB, IL6
3MP:00053917.6DSG1, DSG3, EDNRA, EDNRB, IL6

Publications for Bullous Impetigo

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Articles related to Bullous Impetigo:

(show all 49)
idTitleAuthorsYear
1
Recent trends of cervical cancer and Cervical Intraepithelial Neoplasia 3 (CIN3) in Israel. (25690481)
2015
2
Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function. (25864709)
2015
3
Probing the stiffness of isolated nucleoli by atomic force microscopy. (24297448)
2014
4
Frequency of C9orf72 repeat expansions in amyotrophic lateral sclerosis: a Belgian cohort study. (23870417)
2013
5
Increased axonal regeneration and swellings in intraepidermal nerve fibers characterize painful phenotypes of diabetic neuropathy. (23685187)
2013
6
Doppler sonographic evaluation of arteriovenous shunt flow in a fetus with dural sinus malformation. (23551661)
2013
7
Female Sexual Dysfunction Among Egyptian Patients with Chronic Hepatitis C. (24283464)
2013
8
Lactulose in the treatment of hepatic encephalopathy: new evidence for an old modality. (22823914)
2012
9
Characterization of Epstein-Barr virus (EBV)-infected cells in EBV-associated hemophagocytic lymphohistiocytosis in two patients with X-linked lymphoproliferative syndrome type 1 and type 2. (22325832)
2012
10
Cellular transcripts of chicken brain tissues in response to H5N1 and Newcastle disease virus infection. (22361110)
2012
11
Blocking of I^-adrenergic receptors during the subfertile period inhibits spontaneous ovarian cyst formation in rats. (22407436)
2012
12
Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study. (22594374)
2012
13
Retropancreatic cystic lymphangioma - considerations upon a case. (21424100)
2011
14
A common promoter variant of TBX21 is associated with allele specific binding to Yin-Yang 1 and reduced gene expression. (21272048)
2011
15
T-cell infiltration in autosomal dominant neovascular inflammatory vitreoretinopathy. (20596252)
2010
16
Closer look at autism and the measles-mumps-rubella vaccine. (21071320)
2010
17
Characterization of ductal and lobular breast carcinomas using novel prolactin receptor isoform specific antibodies. (21144038)
2010
18
Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell-cell detachment and processing of adhesion molecules via mechanisms that involve PKC. (19818770)
2010
19
Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients. (20513982)
2010
20
Incidence and predictors of silent myocardial infarction in type 2 diabetes and the effect of fenofibrate: an analysis from the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. (19797259)
2010
21
Sex hormone-binding globulin genetic variation: associations with type 2 diabetes mellitus and polycystic ovary syndrome. (21178921)
2010
22
Preoperative serum levels of serum VEGF-C is associated with distant metastasis in colorectal cancer patients. (19084972)
2009
23
The expression of activin-betaA- and -betaB-subunits, follistatin, and activin type II receptors in fallopian tubes bearing an ectopic pregnancy. (17971430)
2008
24
ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells. (18063589)
2008
25
Risk factors for acute graft-versus-host disease after human leukocyte antigen-identical sibling transplants for adults with leukemia. (18981462)
2008
26
Polymorphisms of the NER pathway genes, ERCC1 and XPD are associated with esophageal adenocarcinoma risk. (18478337)
2008
27
Respiratory syncytial virus (RSV) evades the human adaptive immune system by skewing the Th1/Th2 cytokine balance toward increased levels of Th2 cytokines and IgE, markers of allergy--a review. (16972040)
2006
28
Visceral clear cell sarcoma of soft tissue with confirmation by EWS-ATF1 fusion detection. (16517477)
2006
29
Resolution of pulmonary and cerebral nocardiosis in renal transplant patient despite continued immunosuppression: a case report. (14612077)
2003
30
Migraine with aura during pregnancy. (12864766)
2003
31
Cost-effective screening for trichomoniasis. (12095452)
2002
32
Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors. (12123746)
2002
33
Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells. (11230753)
2001
34
Suppression of multiple sclerosis in the rat during infection with Trichinella pseudospiralis. (10958467)
2000
35
A second calcium regulator of rod outer segment membrane guanylate cyclase, ROS-GC1: neurocalcin. (10504230)
1999
36
Human papillomavirus and urological tumours: I. Basic science and role in penile cancer. (10510097)
1999
37
Socioeconomic status, standard of living, and neurotic disorder. (9853464)
1998
38
Immunologic activation during pregnancy: serial measurement of lymphocyte phenotype and serum activation molecules in HIV-infected and uninfected women. (9234214)
1997
39
5-HT1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs. (9243618)
1997
40
Progressive B cell apoptosis and expression of Fas ligand during human immunodeficiency virus type 1 infection. (9264290)
1997
41
Genetic variants of the renin-angiotensin system, diabetic nephropathy and hypertension. (9049480)
1997
42
Antisense manganese superoxide dismutase mRNA inhibits the antiviral action of interferon-gamma and interferon-alpha. (8640453)
1996
43
The social isolation of young men with quadriplegia. (7855409)
1995
44
Functional antagonism between the estrogen receptor and Fos in the regulation of c-fos protooncogene transcription. (8114761)
1993
45
Changes in beta 2-glycoprotein I antigenicity induced by phospholipid binding. (7684533)
1993
46
Cooperative binding is not required for activation of muscle phosphorylase. (1445866)
1992
47
Atypical Creutzfeldt-Jakob disease in an American family with an insert mutation in the PRNP amyloid precursor gene. (1736177)
1992
48
Nodular goiter: a histo-cytological study with some emphasis on pitfalls of fine-needle aspiration cytology. (1638942)
1992
49

Variations for Bullous Impetigo

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Expression for genes affiliated with Bullous Impetigo

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Search GEO for disease gene expression data for Bullous Impetigo.

Pathways for genes affiliated with Bullous Impetigo

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Pathways related to Bullous Impetigo according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5EDNRA, EDNRB
29.5EDNRA, EDNRB
39.0CALCA, IL6
48.9EDNRA, EDNRB, IL6
58.7CALCA, EDNRA, EDNRB

GO Terms for genes affiliated with Bullous Impetigo

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Biological processes related to Bullous Impetigo according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1endothelin receptor signaling pathwayGO:008610010.2EDNRA, EDNRB
2enteric nervous system developmentGO:004848410.1EDNRA, EDNRB
3vasoconstrictionGO:004231010.0EDNRA, EDNRB
4regulation of epithelial cell proliferationGO:005067810.0EDNRA, EDNRB
5regulation of blood pressureGO:00082179.9EDNRA, EDNRB
6positive regulation of cytosolic calcium ion concentrationGO:00072049.8EDNRA, EDNRB
7positive regulation of ERK1 and ERK2 cascadeGO:00703749.6EDNRA, IL6
8positive regulation of protein phosphorylationGO:00019349.6EDNRA, EDNRB
9sensory perception of painGO:00192339.6EDNRA, EDNRB
10response to yeastGO:00018789.4CALCA, IL6
11cellular response to lipopolysaccharideGO:00712229.4EDNRB, IL6
12defense response to Gram-negative bacteriumGO:00508299.3CALCA, IL6
13monocyte chemotaxisGO:00025489.2CALCA, IL6
14activation of adenylate cyclase activityGO:00071909.1CALCA, EDNRA
15response to organic cyclic compoundGO:00140709.0EDNRA, IL6
16cellular response to tumor necrosis factorGO:00713568.9CALCA, IL6
17agingGO:00075688.8CALCA, EDNRA, IL6

Sources for Bullous Impetigo

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet