MCID: BLL012
MIFTS: 35

Bullous Impetigo malady

Categories: Skin diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Bullous Impetigo

Aliases & Descriptions for Bullous Impetigo:

Name: Bullous Impetigo 56 52 69

Characteristics:

Orphanet epidemiological data:

56
bullous impetigo
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:



External Ids:

Orphanet 56 ORPHA36237
UMLS via Orphanet 70 C0021100
ICD10 via Orphanet 34 L01.0

Summaries for Bullous Impetigo

MalaCards based summary : Bullous Impetigo is related to impetigo and pemphigus, and has symptoms including septic arthritis, recurrent bacterial skin infections and abnormal blistering of the skin. An important gene associated with Bullous Impetigo is DSG1 (Desmoglein 1), and among its related pathways/superpathways are Pathways in cancer and Apoptotic cleavage of cellular proteins. Affiliated tissues include skin, and related phenotypes are digestive/alimentary and respiratory system

Wikipedia : 71 Bullous Impetigo is a skin condition that characteristically occurs in the newborn, and is caused by a... more...

Related Diseases for Bullous Impetigo

Diseases related to Bullous Impetigo via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
id Related Disease Score Top Affiliating Genes
1 impetigo 11.6
2 pemphigus 10.1
3 mesenchymal cell neoplasm 10.1 CALCA IL6
4 myalgia-eosinophilia syndrome associated with tryptophan 10.1 DSG1 DSG3
5 nodular prostate 10.1 CALCA IL6
6 peripheral t-cell lymphoma 10.1 DSG1 DSG3
7 labyrinthine bilateral reactive loss 10.1 EDNRA IL6
8 central nervous system lymphoma 10.1 CALCA IL6
9 acute pulmonary heart disease 10.1 DSG1 DSG3
10 infantile hypotonia 10.1 CALCA EDNRA
11 subglottis neoplasm 10.1 DSG1 DSG3
12 herpes zoster 10.1 DSG1 DSG3
13 pharc syndrome 10.0 DSG1 DSG3
14 dysbaric osteonecrosis 10.0 CALCA IL6
15 folinic acid-responsive seizures 10.0 DSG1 DSG3
16 pol iii-related leukodystrophies 10.0 DSG1 DSG3
17 blue toe syndrome 10.0 EDNRA IL6
18 hirschsprung disease 1 10.0 CALCA EDNRB
19 hemopericardium 10.0 CALCA EDNRB
20 wound botulism 10.0 DSG1 EDNRB
21 pompholyx 10.0 DSG1 DSG3
22 adenocarcinoma 10.0 EDNRA EDNRB
23 nervous system disease 10.0 EDNRA EDNRB
24 bladder papillary transitional cell neoplasm 10.0 CALCA IL6
25 miliaria rubra 10.0
26 miliaria 10.0
27 benign idiopathic neonatal seizures 10.0 EDNRA EDNRB
28 monocytic leukemia 10.0 DSG1 DSG3
29 zellweger syndrome 10.0 EDNRA EDNRB
30 articulation disorder 9.9 DSG1 DSG3 IL6
31 pemphigus foliaceus 9.9
32 herpes simplex 9.9
33 esophagus carcinoma in situ 9.8 DSG1 EDNRA EDNRB
34 neutropenia, severe congenital, 5, autosomal recessive 9.8 CALCA EDNRB
35 toxic shock syndrome 9.7
36 dermatitis 9.7
37 atopic dermatitis 9.7
38 neonatal herpes 9.7
39 streptococcal toxic-shock syndrome 9.7
40 hiv-1 9.7
41 uterine ligament clear cell adenocarcinoma 9.7 EDNRB IL6
42 acute cor pulmonale 9.7 CALCA DSG1 EDNRB IL6
43 immunodeficiency by defective expression of hla class 1 9.2 CALCA DSG1 DSG3 EDNRA EDNRB IL6

Graphical network of the top 20 diseases related to Bullous Impetigo:



Diseases related to Bullous Impetigo

Symptoms & Phenotypes for Bullous Impetigo

Human phenotypes related to Bullous Impetigo:

56 32 (show all 8)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 septic arthritis 56 32 Occasional (29-5%) HP:0003095
2 recurrent bacterial skin infections 56 32 Very frequent (99-80%) HP:0005406
3 abnormal blistering of the skin 56 32 Very frequent (99-80%) HP:0008066
4 erythema 56 32 Very frequent (99-80%) HP:0010783
5 abnormality of the lymphatic system 56 32 Occasional (29-5%) HP:0100763
6 sepsis 56 32 Occasional (29-5%) HP:0100806
7 glomerulopathy 56 32 Occasional (29-5%) HP:0100820
8 pustule 56 32 Very frequent (99-80%) HP:0200039

MGI Mouse Phenotypes related to Bullous Impetigo:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.56 DSG3 EDNRA EDNRB IL6
2 respiratory system MP:0005388 9.46 DSG3 EDNRA EDNRB IL6
3 skeleton MP:0005390 9.35 DSG1 DSG3 EDNRA EDNRB IL6
4 vision/eye MP:0005391 9.02 DSG1 DSG3 EDNRA EDNRB IL6

Drugs & Therapeutics for Bullous Impetigo

Interventional clinical trials:


id Name Status NCT ID Phase
1 Pharmacokinetics of Retapamulin in Pediatric Subjects With Uncomplicated Skin Infections. Completed NCT00555061 Phase 4
2 Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo Completed NCT02090764 Phase 3
3 Efficacy and Safety of Ozenoxacin 1% Cream Versus Placebo in the Treatment of Patients With Impetigo Completed NCT01397461 Phase 3

Search NIH Clinical Center for Bullous Impetigo

Genetic Tests for Bullous Impetigo

Anatomical Context for Bullous Impetigo

MalaCards organs/tissues related to Bullous Impetigo:

39
Skin

Publications for Bullous Impetigo

Articles related to Bullous Impetigo:

(show top 50) (show all 53)
id Title Authors Year
1
Case of bullous impetigo with enormous bulla developing into staphylococcal scalded skin syndrome. ( 26603272 )
2016
2
Staphylococcal bullous impetigo in a neonate. ( 27458596 )
2016
3
Bullous impetigo and pregnancy: Case report and review of blistering conditions in pregnancy. ( 27617460 )
2016
4
Bullous Impetigo Rapid Diagnostic and Therapeutic Quiz: A Model for Assessing Basic Dermatology Knowledge of Primary Care Providers. ( 27599660 )
2016
5
Bullous impetigo. ( 24736928 )
2014
6
Value of serum procalcitonin and interleukin-6 in patients with bullous impetigo and staphylococcal scalded skin syndrome. ( 25298068 )
2014
7
Paediatric bullous dermatoses. Linear immunoglobulin A (IgA) dermatosis. Bullous impetigo. Bullous insect bite reaction. Neonatal Herpes simplex virus (HSV) infection. ( 23111154 )
2013
8
Outbreak of bullous impetigo caused by Staphylococcus aureus strains of phage type 3C/71 in a maternity ward linked to nasal carriage of a healthcare worker. ( 22378195 )
2012
9
The use of typing methods and infection prevention measures to control a bullous impetigo outbreak on a neonatal ward. ( 23168170 )
2012
10
Bullous impetigo associated with Abiotrophia defectiva in an immunocompetent adult. ( 22493280 )
2012
11
Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage. ( 21430094 )
2011
12
Dermacase. Bullous impetigo. ( 18272632 )
2008
13
Outbreak of staphylococcal bullous impetigo in a maternity ward linked to an asymptomatic healthcare worker. ( 17945394 )
2007
14
Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome. ( 17505275 )
2007
15
Is blistering distal dactylitis a variant of bullous impetigo? ( 17362240 )
2007
16
Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. ( 17065642 )
2006
17
Review: topical mupirocin or fusidic acid may be more effective than oral antibiotics for limited non-bullous impetigo. ( 15688485 )
2005
18
Bullous impetigo of the face after epilation by threading. ( 16172329 )
2005
19
Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in infants. ( 15482208 )
2004
20
Desmosomes and disease: pemphigus and bullous impetigo. ( 15363804 )
2004
21
Generalized bullous impetigo in a neonate. ( 15575854 )
2004
22
Clinicopathological case 3: pemphigus foliaceus; bullous impetigo; subcorneal pustular dermatoses. ( 12823325 )
2003
23
Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in skin lesions of bullous impetigo, atopic dermatitis and pemphigus foliaceus. ( 12653745 )
2003
24
Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan. ( 11992289 )
2002
25
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. ( 12093888 )
2002
26
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. ( 11062541 )
2000
27
Bullous impetigo. ( 9369884 )
1997
28
Vesicles and bulla in an infant. Bullous varicella (chicken pox complicated by bullous impetigo). ( 8285728 )
1994
29
Bullous impetigo caused by group A streptococci. A case report. ( 1350146 )
1992
30
Bullous impetigo in homosexual men--a risk marker for HIV-1 infection? ( 1607190 )
1992
31
Is penicillin still the drug of choice for non-bullous impetigo? ( 1681172 )
1991
32
Bullous impetigo and localized scalded skin syndrome in the elderly. ( 3623889 )
1987
33
Antibiotic susceptibilities of Staphylococcus aureus strains derived from furuncle and bullous impetigo. ( 3894459 )
1985
34
Epidemic bullous impetigo in a nursery due to a nasal carrier of Staphylococcus aureus: role of epidemiology and control measures. ( 6376403 )
1984
35
Effects of serum albumin on coagulase release from Staphylococcus aureus derived from bullous impetigo. ( 6386912 )
1984
36
What histologic finding distinguishes superficial pemphigus and bullous impetigo? ( 6375421 )
1984
37
Vacuoles in the upper part of the epidermis as a clue to eventuation of superficial pemphigus and bullous impetigo. ( 6731731 )
1984
38
Re-emergence of bullous impetigo. ( 6799136 )
1982
39
Sequential bullous impetigo and cutaneous Herpes simplex virus infection. ( 6761658 )
1982
40
Re-emergence of bullous impetigo. ( 6799044 )
1981
41
Falsely normal direct immunofluorescent microscopic fundings in bullous impetigo. ( 7027964 )
1981
42
Bullous impetigo caused by Streptococcus salivarius: a case report. ( 7002959 )
1980
43
The epidermolytic toxin of Staphylococcus aureus: its failure to bind to cells and its detection in blister fluids of patients with bullous impetigo. ( 701847 )
1978
44
Staphylococcal scalded skin syndrome. II. Serum level of anti exfoliatin and anti alpha-toxin in patients with staphylococcal scalded skin syndrome or bullous impetigo. ( 15461328 )
1977
45
Bullous impetigo. Occurrence of localized scalded skin syndrome in an adult. ( 782365 )
1976
46
Skin complications of heroin addiction. Bullous impetigo. ( 4513637 )
1973
47
An epidemic of bullous impetigo arising from a central admission-observation nursery. ( 5059306 )
1972
48
Bullous impetigo due to group II Staphylococcus aureus. An epidemic in a normal newborn nursery. ( 5422851 )
1970
49
The etiology of poral closure. II. The role of staphylococcal infection in miliaria rubra and bullous impetigo. ( 15437052 )
1950
50
The etiology of poral closure; an experimental study of miliaria rubra, bullous impetigo and related diseases of the skin. I. An historical review of the causation of miliaria. ( 15437051 )
1950

Variations for Bullous Impetigo

Expression for Bullous Impetigo

Search GEO for disease gene expression data for Bullous Impetigo.

Pathways for Bullous Impetigo

GO Terms for Bullous Impetigo

Cellular components related to Bullous Impetigo according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 8.96 DSG1 DSG3
2 desmosome GO:0030057 8.62 DSG1 DSG3

Biological processes related to Bullous Impetigo according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.58 CALCA EDNRB IL6
2 cellular response to tumor necrosis factor GO:0071356 9.54 CALCA IL6
3 cornification GO:0070268 9.52 DSG1 DSG3
4 response to heat GO:0009408 9.51 CALCA IL6
5 monocyte chemotaxis GO:0002548 9.49 CALCA IL6
6 activation of adenylate cyclase activity GO:0007190 9.48 CALCA EDNRA
7 vasodilation GO:0042311 9.46 CALCA EDNRB
8 response to pain GO:0048265 9.43 CALCA EDNRB
9 positive regulation of cytosolic calcium ion concentration GO:0007204 9.43 CALCA EDNRA EDNRB
10 vasoconstriction GO:0042310 9.37 EDNRA EDNRB
11 negative regulation of bone resorption GO:0045779 9.32 CALCA IL6
12 enteric nervous system development GO:0048484 9.16 EDNRA EDNRB
13 regulation of blood pressure GO:0008217 9.13 CALCA EDNRA EDNRB
14 endothelin receptor signaling pathway GO:0086100 8.62 EDNRA EDNRB

Molecular functions related to Bullous Impetigo according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endothelin receptor activity GO:0004962 8.62 EDNRA EDNRB

Sources for Bullous Impetigo

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
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32 HPO
33 ICD10
34 ICD10 via Orphanet
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37 KEGG
38 LifeMap
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42 MeSH
43 MESH via Orphanet
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48 NDF-RT
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54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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