MCID: BLL006
MIFTS: 59

Bullous Pemphigoid malady

Categories: Rare diseases, Skin diseases, Immune diseases

Aliases & Classifications for Bullous Pemphigoid

About this section
Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 39MeSH, 40MESH via Orphanet, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Bullous Pemphigoid:

Name: Bullous Pemphigoid 11 48 54 13 68
Senile Dermatitis Herpetiformis 48 68
Benign Pemphigus 48 68
Pemphigoid, Bullous 39
 
Pemphigoid Bullous 50
Old Age Pemphigus 48
Parapemphigus 48
Pemphigoid 48

Characteristics:

Orphanet epidemiological data:

54
bullous pemphigoid:
Age of onset: All ages

Classifications:

Orphanet: 54 
Rare skin diseases


External Ids:

Disease Ontology11 DOID:8506
ICD1030 L12, L12.0, L12.9
ICD9CM32 694.5
MeSH39 D010391
Orphanet54 ORPHA703
MESH via Orphanet40 D010391
UMLS via Orphanet69 C0030805
ICD10 via Orphanet31 L12.0

Summaries for Bullous Pemphigoid

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NIH Rare Diseases:48 Bullous pemphigoid is a skin disorder characterized by large blisters. the blisters are usually located on the arms, legs, or middle of the body. in some people, the mouth or genitals are also affected. the blisters may break open and form ulcers or open sores. bullous pemphigoid usually occurs in older persons and is rare in young people. symptoms may come and go. in most patients, the condition goes away after several years. bullous pemphigoid is an autoimmune disorder which occurs when the body's immune system attacks and destroys healthy body tissue by mistake. treatment may include corticosteroids taken by mouth or applied to the skin. medicines that suppress the immune system may also be prescribed. for some, antibiotics in the tetracycline family are useful. last updated: 8/10/2016

MalaCards based summary: Bullous Pemphigoid, also known as senile dermatitis herpetiformis, is related to epidermolysis bullosa and actinic keratosis, and has symptoms including Array, Array and Array. An important gene associated with Bullous Pemphigoid is COL17A1 (Collagen Type XVII Alpha 1 Chain), and among its related pathways are Staphylococcus aureus infection and a6b1 and a6b4 Integrin signaling. The drug sulfapyridine pwdr has been mentioned in the context of this disorder. Affiliated tissues include skin, testes and t cells, and related mouse phenotypes are craniofacial and digestive/alimentary.

Disease Ontology:11 An autoimmune disease of skin and connective tissue characterized by large blisters.

Wikipedia:71 Bullous pemphigoid is an acute or chronic autoimmune skin disease, involving the formation of blisters,... more...

Related Diseases for Bullous Pemphigoid

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Diseases related to Bullous Pemphigoid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 241)
idRelated DiseaseScoreTop Affiliating Genes
1epidermolysis bullosa30.7CCL11, CD79A, DSG1, IL5, RNASE3
2actinic keratosis29.7CD79A, IL5, RNASE3
3herpes zoster29.1CD79A, COL17A1, DSG1, DSG3, DST, EVPL
4lichen planus pemphigoides11.3
5autoimmune disease, multisystem, infantile-onset, 211.0
6pemphigus10.5
7epidermolysis bullosa acquisita10.4
8psoriasis10.4
9cicatricial pemphigoid10.3
10linear hamartoma syndrome10.3COL17A1, DST, ITGB4
11dermatitis10.3
12x-linked intellectual disability-precocious puberty-obesity syndrome10.3DSG3, DSP
13dermatitis herpetiformis10.3
14latent syphilis10.3CCL11, IL5, RNASE3
15necrotizing gastritis10.3CCL11, IL5, RNASE3
16pemphigus vulgaris10.3
17restrictive cardiomyopathy10.3IL5, RNASE3
18cerebral primitive neuroectodermal tumor10.3CCL11, IL5, RNASE3
19trachea leiomyoma10.3CCL11, IL5, RNASE3
20visceral steatosis10.3CCL11, IL5, RNASE3
21luminal breast carcinoma10.3HLA-DQB1, IL5, RNASE3
22ethmoid sinusitis10.3CCL11, IL5, RNASE3
23childhood malignant mesenchymoma10.3CCL11, IL5, RNASE3
24cardiomyopathy, dilated, 1bb10.3DSG1, DSP
25inflamed seborrheic keratosis10.3CCL11, IL5, RNASE3
26lin-gettig syndrome10.3COL17A1, HLA-DQB1, HLA-DRB1
27hydrophthalmos10.3CCL11, IL5, RNASE3
28patellar tendinitis10.3CCL11, IL5, RNASE3
29epidermolysis bullosa simplex with nail dystrophy10.3ITGB4, PLEC
30apple allergy10.3HLA-DQB1, HLA-DRB1
31herpes gestationis10.2
32thyroid hyalinizing trabecular adenoma10.2CCL11, IL5, RNASE3
33colon adenocarcinoma10.2CCL11, IL5, RNASE3
34heart septal defect10.2CD79A, RNASE3
35hemoglobin d disease10.2HLA-DQB1, HLA-DRB1
36acute dacryoadenitis10.2CCL11, IL5, RNASE3
37pulmonary tuberculosis10.2CCL11, IL5, RNASE3
38myalgia-eosinophilia syndrome associated with tryptophan10.2DSG1, DSG3, DST
39x-linked intellectual disability-epilepsy-progressive joint contractures-dysmorphism syndrome10.2DSG1, PPL
40spontaneous ocular nystagmus10.2CCL11, IL5, RNASE3
41pemphigus foliaceus10.2
42spastic diplegia10.2CCL11, CD79A, IL5
43brown shrimp allergy10.2CD79A, IL5, RNASE3
44frmd7-related infantile nystagmus10.2ITGA6, ITGB4, PLEC
45birth defects10.2CCL11, IL5, RNASE3
46metal allergy10.2CD79A, IL5, RNASE3
47small intestine lymphoma10.2CD79A, IL5, RNASE3
48orbit alveolar rhabdomyosarcoma10.2CD79A, IL5, RNASE3
49bare lymphocyte syndrome, type i10.2CCL11, IL5, RNASE3
50barbiturate abuse10.2CCL11, CD79A, HLA-DQB1

Comorbidity relations with Bullous Pemphigoid via Phenotypic Disease Network (PDN):


Deficiency AnemiaSchizophreniform Disorder
Heart DiseaseProtein-Energy Malnutrition
Acute CystitisDecubitus Ulcer
Pemphigus

Graphical network of the top 20 diseases related to Bullous Pemphigoid:



Diseases related to bullous pemphigoid

Symptoms & Phenotypes for Bullous Pemphigoid

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Human phenotypes related to Bullous Pemphigoid:

 54 64 (show all 10)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 diabetes mellitus64 54 Very frequent (99-80%) HP:0000819
2 eczema64 54 Very frequent (99-80%) HP:0000964
3 urticaria64 54 Very frequent (99-80%) HP:0001025
4 weight loss64 54 Very frequent (99-80%) HP:0001824
5 recurrent infections64 54 Very frequent (99-80%) HP:0002719
6 autoimmunity64 54 Very frequent (99-80%) HP:0002960
7 psoriasis64 54 Frequent (79-30%) HP:0003765
8 abnormal blistering of the skin64 54 Very frequent (99-80%) HP:0008066
9 erythema64 54 Very frequent (99-80%) HP:0010783
10 macule64 54 Very frequent (99-80%) HP:0012733

MGI Mouse Phenotypes related to Bullous Pemphigoid according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.0DSG3, DSP, ITGA6, ITGB4, LAMA3, LAMB3
2MP:00053818.5DSG3, DSP, HLA-DQB1, IL5, ITGA6, ITGB4
3MP:00053878.0CCL11, CD79A, DSG3, HLA-DQB1, IL5, ITGA6
4MP:00107718.0DSG3, DSP, EVPL, ITGA6, ITGB4, LAMA3
5MP:00053887.5CCL11, DSG3, HLA-DQB1, IL5, ITGA6, ITGB4

Drugs & Therapeutics for Bullous Pemphigoid

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Drugs for Bullous Pemphigoid (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 82)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Prednisoneapproved, vet_approvedPhase 4139853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
2
Omalizumabapproved, investigationalPhase 4145242138-07-4
Synonyms:
242138-07-4
D05251
Ig gamma-1 chain C region
Omalizumab
 
Omalizumab (USAN/INN)
Omalizumab (genetical recombination)
Omalizumab (genetical recombination) (JAN)
Xolair
Xolair (TN)
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 313168
4
ClobetasolPhase 4, Phase 37925122-46-732798, 5311051
Synonyms:
(11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
(9R,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
25122-41-2
AC-1775
AC1L1OG6
AC1NDRJ9
AC1NSJWK
BB_NC-1906
C22H28ClFO4
CHEBI:205919
CHEMBL1201362
CID10341542
CID32797
 
CID4630419
CID5311051
CID9844480
Clobecort Amex
Clobecort Amex (TN)
Clobetasol (INN)
Clobetasol [INN:BAN]
Clobetasolum
Clobetasolum [INN-Latin]
Clofenazon
D07715
EINECS 246-633-8
LS-174086
MolPort-005-909-335
NCGC00164580-01
STK801976
UNII-ADN79D536H
ZINC26892643
clobetasol
5HormonesPhase 4, Phase 314415
6Hormone AntagonistsPhase 4, Phase 313180
7Anti-Inflammatory AgentsPhase 4, Phase 310729
8glucocorticoidsPhase 4, Phase 35103
9Respiratory System AgentsPhase 44997
10Anti-Allergic AgentsPhase 41522
11AntibodiesPhase 4, Phase 3, Phase 2, Phase 16394
12Anti-Asthmatic AgentsPhase 43488
13Antineoplastic Agents, HormonalPhase 45592
14Immunoglobulin EPhase 436
15ImmunoglobulinsPhase 4, Phase 3, Phase 2, Phase 16394
16
MethotrexateapprovedPhase 315511959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
17
rituximabapprovedPhase 3, Phase 1, Phase 21692174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
18
Mycophenolate mofetilapproved, investigationalPhase 3, Phase 2952128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
19
Mycophenolic acidapprovedPhase 3, Phase 295224280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
20
leucovorinapproved, NutraceuticalPhase 3323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
21
Folic Acidapproved, nutraceutical, vet_approvedPhase 3, Phase 1, Phase 2439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
22Vitamin B ComplexPhase 3, Phase 1, Phase 24337
23Nucleic Acid Synthesis InhibitorsPhase 34962
24Immunosuppressive AgentsPhase 3, Phase 213086
25Antimetabolites, AntineoplasticPhase 3, Phase 27361
26AntimetabolitesPhase 3, Phase 2, Phase 112054
27Dermatologic AgentsPhase 3, Phase 1, Phase 25806
28Antirheumatic AgentsPhase 3, Phase 2, Phase 110956
29Folic Acid AntagonistsPhase 32257
30Antibiotics, AntitubercularPhase 3, Phase 27180
31Anti-Bacterial AgentsPhase 3, Phase 211226
32Rho(D) Immune GlobulinPhase 3, Phase 2, Phase 1326
33gamma-GlobulinsPhase 3, Phase 2, Phase 1326
34Immunoglobulins, IntravenousPhase 3, Phase 2, Phase 1333
35FolateNutraceuticalPhase 3, Phase 1, Phase 24392
36Vitamin B9NutraceuticalPhase 3, Phase 1, Phase 24392
37
Leflunomideapproved, investigationalPhase 26775706-12-63899
Synonyms:
210165-51-8
4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl
4-isoxazolecarboxamide,5-methyl-N-(4-(trifluoromethyl)phenyl)
5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide
5-Methylisoxazole-4-(4-trifluoromethylcarboxanilide)
5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide
5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
5-methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide
5-methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide
75706-12-6
A77 1486
AB00052389
AC-6796
AC1L1GYK
AC1Q2EVA
AKOS000265193
AP-501/42475599
Arava
Arava (TN)
Arava, Leflunomide
Aventis Behring Brand of Leflunomide
Aventis Brand of Leflunomide
Aventis Pharma Brand of Leflunomide
BIDD:PXR0189
BPBio1_000930
BRD-K78692225-001-03-9
BSPBio_000844
C045463
C07905
CAS-75706-12-6
CHEBI:6402
CHEMBL960
CID3899
D00749
DB01097
DivK1c_000916
EU-0100649
HMS1570K06
HMS1922M06
HMS2090O12
HMS502N18
HSDB 7289
HWA 486
HWA-486
Hoechst Brand of Leflunomide
I06-2131
IDI1_000916
KBio1_000916
KBio2_000802
KBio2_003370
KBio2_005938
KBioSS_000802
L 5025
L5025_SIGMA
 
LS-86580
Leflunomid
Leflunomida
Leflunomida [INN-Spanish]
Leflunomide
Leflunomide (JAN/USAN/INN)
Leflunomide [USAN:INN]
Leflunomidum
Leflunomidum [INN-Latin]
Lefunomide
Lefunomide [INN-Spanish]
Lefunomide [Inn-Spanish]
Lopac-L-5025
Lopac0_000649
MLS-0003109.0001
MLS000069648
MLS001076267
MolPort-002-345-613
N-(4'-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide
N-(4-trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide
NCGC00015610-01
NCGC00015610-02
NCGC00015610-03
NCGC00015610-07
NCGC00015610-12
NCGC00022625-03
NCGC00022625-04
NCGC00022625-05
NCGC00022625-06
NCGC00022625-07
NCGC00022625-08
NINDS_000916
NSC677411
Prestwick0_000772
Prestwick1_000772
Prestwick2_000772
Prestwick3_000772
Prestwick_87
RS-34821
S1247_Selleck
SMR000058209
SPBio_002783
SPECTRUM1503927
SU 101
SU 101 (pharmaceutical)
SU-101
SU101
Spectrum5_000850
Spectrum_000322
TL8005179
UNII-G162GK9U4W
ZINC00004840
alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-P-toluidide
alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide
leflunomide
lefunamide
38
AzathioprineapprovedPhase 2177446-86-62265
Synonyms:
446-86-6
55774-33-9 (hydrochloride salt)
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]
6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine
6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine
6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
6-(Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(Methyl-p-nitro-5-imidazolyl)thiopurine
6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine
6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine
6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine
6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
A 4638
A2593_SIAL
A4638_SIAL
A4638_SIGMA
AB00443544
AB00443544-03
AC-4230
AC1L1DAL
AC1Q3Z1F
AI-981/34845012
AI3-50290
Azamun
Azamun [Czech]
Azanin
Azasan
Azasan (TN)
Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine
Azathioprin
Azathioprine (JP15/USP/INN)
Azathioprine Sodium
Azathioprine [USAN:INN:BAN:JAN]
Azathioprine sodium
Azathioprinum
Azathioprinum [INN-Latin]
Azathiopurine
Azatioprin
Azatioprina
Azatioprina [INN-Spanish]
Azothioprine
B. W. 57-322
BPBio1_000054
BRD-K32821942-001-05-6
BRD-K60324116-001-01-5
BSPBio_000048
BSPBio_001876
BW 57-322
BW 57322
BW-57-322
C06837
C9H7N7O2S
CAS-446-86-6
CBDivE_013132
CCRIS 62
CHEBI:2948
CHEMBL1542
CID2265
CPD000427366
Ccucol
ChemDiv1_002659
Cytostatics
D00238
DB00993
DivK1c_000586
EINECS 207-175-4
EU-0100027
FT-0083532
HMS1568C10
HMS1920E17
 
HMS2091K19
HMS501N08
HMS594I19
HSDB 7084
IDI1_000586
Immuran
Imuran
Imuran (TN)
Imuran (tn)
Imurek
Imurel
KBio1_000586
KBio2_000464
KBio2_002427
KBio2_003032
KBio2_004995
KBio2_005600
KBio2_007563
KBio3_001376
KBio3_002906
KBioGR_000646
KBioGR_002427
KBioSS_000464
KBioSS_002433
LS-123
Lopac-A-4638
Lopac0_000027
MLS001049307
Methylnitroimidazolylmercaptopurine
MolPort-000-745-914
MolPort-000-764-262
MolPort-003-665-485
Muran
NCGC00015060-01
NCGC00015060-02
NCGC00015060-04
NCGC00015060-12
NCGC00090836-01
NCGC00090836-02
NCGC00090836-03
NCGC00090836-04
NCGC00090836-05
NCGC00090836-06
NCGC00094593-01
NCGC00094593-02
NCGC00094593-03
NCI-C03474
NINDS_000586
NSC 39084
NSC-39084
NSC39084
Oprea1_375441
Oprea1_533384
Oprea1_633462
Prestwick0_000094
Prestwick1_000094
Prestwick2_000094
Prestwick3_000094
Prestwick_41
S1721_Selleck
SAM002589938
SDCCGMLS-0065415.P001
SMR000427366
SPBio_000255
SPBio_001987
SPECTRUM1500133
STK831906
STOCK1S-20293
STOCK1S-27186
Spectrum2_000068
Spectrum3_000308
Spectrum4_000243
Spectrum5_000848
Spectrum_000064
Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl)
UNII-MRK240IY2L
WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW
ZINC04258316
[Methyl(nitroimidazolyl)mercaptopurine]
azathioprine
azatiopr in
cMAP_000046
39
Prednisoloneapproved, vet_approvedPhase 2119350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
40
Methylprednisoloneapproved, vet_approvedPhase 2119383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
41
InfliximabapprovedPhase 1, Phase 2392170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
42
Riboflavinapproved, nutraceutical, vet_approvedPhase 1, Phase 217483-88-5493570
Synonyms:
(-)-Riboflavin
1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol
6,7-Dimethyl-9-D-ribitylisoalloxazine
6,7-Dimethyl-9-ribitylisoalloxazine
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
7,8-Dimethyl-10-ribitylisoalloxazine
Beflavin
Beflavine
Benzo[g]pteridine riboflavin deriv.
E 101
E101
Flavaxin
Flavin BB
Flaxain
Food Yellow 15
 
Hyre
Lactobene
Lactoflavin
Lactoflavine
Ribipca
Ribocrisina
Riboderm
Riboflavina
Riboflavine
Riboflavinum
Ribosyn
Ribotone
Ribovel
Russupteridine yellow III
San Yellow B
Vitaflavine
Vitamin B2
Vitamin G
Vitasan B2
43Gastrointestinal AgentsPhase 1, Phase 28402
44MicronutrientsPhase 1, Phase 26001
45Trace ElementsPhase 1, Phase 26001
46VitaminsPhase 1, Phase 25282
47Methylprednisolone HemisuccinatePhase 21193
48Prednisolone acetatePhase 21193
49Prednisolone hemisuccinatePhase 21193
50Methylprednisolone acetatePhase 21193

Interventional clinical trials:

(show all 41)
idNameStatusNCT IDPhase
1Efficacy and Safety of Omalizumab in Bullous PemphigoidCompletedNCT00472030Phase 4
2Comparison of Two Therapeutic Strategies of Dermoval in Treatment of Bullous PemphigusCompletedNCT00213421Phase 4
3Evaluation of Fluid Retention Due to Superpotent Topical CorticosteroidRecruitingNCT02360202Phase 4
4Topical Steroids Alone or Associated With Methotrexate in Bullous PemphigoidUnknown statusNCT02313870Phase 3
5Efficiency and Tolerance of Rituximab (mabthéra) in Bullous PemphigoidCompletedNCT00525616Phase 3
6Phase III Clinical Trial of NPB-01 in Patients With Bullous Pemphigoid Unresponsive to CorticosteroidsCompletedNCT01408550Phase 3
7Pharmacokinetics Study of Mycophenolic Acid in Patients With an Autoimmune Bullous Dermatose, Pemphigus or Cicatricial Pemphigoid.Not yet recruitingNCT02993133Phase 3
8Leflunomide Associated With Topical Corticosteroids for Bullous PemphigoidUnknown statusNCT00802243Phase 2
9Clinical Trial of NPB-01 in Patients With Bullous Pemphigoid Unresponsive to Corticosteroids.CompletedNCT00809822Phase 2
10Rituximab in the Treatment of Patients With Bullous PemphigoidCompletedNCT00286325Phase 1, Phase 2
11Azathioprine or Mycophenolate Mofetil for Bullous PemphigoidCompletedNCT00431119Phase 2
12Anti-IL-5 Therapy in Bullous Pemphigoid (BP)CompletedNCT01705795Phase 2
13Clinical Trial Evaluating Rituximab in Ocular Cicatricial PemphigoidCompletedNCT00584935Phase 1, Phase 2
14Evaluation of Safety, Efficacy and Pharmacodynamic Effect of Bertilimumab in Patients With Bullous PemphigoidRecruitingNCT02226146Phase 2
15Limbal Epithelial Stem Cell Transplantation: a Phase II Multicenter TrialRecruitingNCT02318485Phase 2
16Use of Cross-linked Donor Corneas as Carriers for the Boston KeratoprosthesisRecruitingNCT01582880Phase 1, Phase 2
17Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet TransplantationAvailableNCT02149732Phase 1, Phase 2
18Ixekizumab in the Treatment of Bullous PemphigoidNot yet recruitingNCT03099538Phase 2
19Safety, Efficacy and PK/PD of QGE031 vs. Placebo in Patients With Active Bullous Pemphigoid Despite Oral Steroid TreatmentTerminatedNCT01688882Phase 2
20Pilot Efficacy and Safety Study of Oral DF2156A in Patients With Active Bullous PemphigoidTerminatedNCT01571895Phase 2
21Topical Infliximab in Autoimmune Eyes With KeratoprosthesisWithdrawnNCT02126020Phase 1, Phase 2
22The Improvement of Limbal Epithelial Culture Technique by Using Collagenase to Isolate Limbal Stem CellsUnknown statusNCT02202642Phase 1
23Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid MalignanciesCompletedNCT00691210Phase 1
24Safety, Tolerability and Activity of TNT009 in Healthy Volunteers and Patients With Complement Mediated DisordersRecruitingNCT02502903Phase 1
25Topical Infliximab for Sterile Corneal MeltNot yet recruitingNCT02987686Phase 1
26Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory ConditionsWithdrawnNCT02042027Phase 1
27Explore the Mechanisms of Pruritus in Bullous Pemphigoid Patients During RemissionUnknown statusNCT01265082
28Wound Dressings for Pemphigus and PemphigoidUnknown statusNCT02365675
29Interest of Dosage of Anti-PB230, Anti-PB180 and Cytokines for Monitoring of Patients Suffering From Bullous PemphigoidCompletedNCT02883894
30Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort StudyCompletedNCT00116090
31A Study of the Association of Sleep Dysfunction and Burning Mouth SyndromeCompletedNCT00862576
32Observational Study Assessing Outcomes, Treatment Patterns and Related Costs in Patients in Bullous PemphigoidRecruitingNCT02837965
33Genetic Susceptibility and Influence of the Microbiomae in Bullous PemphigoidRecruitingNCT02874079
34Role of Proteasomes in a Dermatological Autoimmune Disease: Bullous PemphigoidRecruitingNCT01559155
35Pruritus and Pemphigoid in Nursing Home PatientsRecruitingNCT02823067
36Autoimmune Blistering Diseases StudyRecruitingNCT02753777
37Identification of Vulnerability Factors in the Course of Pemphigus PatientsRecruitingNCT02237313
38Register of Autoimmune Bullous DermatosesRecruitingNCT02899923
39Prevalence of Cutaneous Autoimmune Phenomena in HIV Infected PatientsRecruitingNCT03129308
40Immune Responses to Antigens in Non-infectious Eye Inflammatory DiseasesEnrolling by invitationNCT00357071
41Serum FFA Desaturase Activity Index in Patients on High Dose CorticosteroidsNot yet recruitingNCT02872584

Search NIH Clinical Center for Bullous Pemphigoid

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: pemphigoid, bullous

Genetic Tests for Bullous Pemphigoid

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Anatomical Context for Bullous Pemphigoid

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MalaCards organs/tissues related to Bullous Pemphigoid:

36
Skin, Testes, T cells, Neutrophil, B cells, Breast, Thyroid

Publications for Bullous Pemphigoid

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Articles related to Bullous Pemphigoid:

(show top 50)    (show all 952)
idTitleAuthorsYear
1
Immunoglobulin E Autoantibodies in Bullous Pemphigoid Detected by Immunoglobulin E Enzyme-Linked Immunosorbent Assays. (27829077)
2017
2
Bullous pemphigoid induced by photodynamic therapy: when light is guilty. (28369769)
2017
3
Survey of bullous pemphigoid in an Italian University hospital: clinical-epidemiological characteristics and follow-up. (28079339)
2017
4
A randomized double-blind trial of intravenous immunoglobulin for bullous pemphigoid. (27876358)
2017
5
Serum levels and tissue expression of interleukin-31 in dermatitis herpetiformis and bullous pemphigoid. (28465041)
2017
6
Complement-independent blistering mechanisms in bullous pemphigoid. (28418613)
2017
7
Increased Risk of Bullous Pemphigoid after First-Ever Stroke: A Population-Based Study. (28467996)
2017
8
Bullous hemorrhagic dermatosis due to enoxaparin use in a bullous pemphigoid patient. (28487841)
2017
9
Extensive milia formation in a young woman with bullous pemphigoid. (28440230)
2017
10
Bullous Pemphigoid associated with Dipeptidyl Peptidase-4 Inhibitors: A Report of Five Cases. (28520234)
2017
11
Membranous glomerulonephropathy in a patient with bullous pemphigoid. (28509127)
2017
12
Successful Management of Acquired Hemophilia A Associated with Bullous Pemphigoid: A Case Report and Review of the Literature. (28458935)
2017
13
Analysis of serum markers of cellular immune activation in patients with bullous pemphigoid. (28500685)
2017
14
Bullous pemphigoid and systemic sclerosis: an incidental association? (28468735)
2017
15
Multimorbidity in Bullous Pemphigoid: a case-control analysis of BP patients with age and gender matched controls. (28485892)
2017
16
A randomised controlled trial to compare the safety, effectiveness and cost-effectiveness of doxycycline (200a88mg/day) with that of oral prednisolone (0.5a88mg/kg/day) for initial treatment of bullous pemphigoid: the Bullous Pemphigoid Steroids and Tetracyclines (BLISTER) trial. (28406394)
2017
17
Rituximab Treatment of Nivolumab-Induced Bullous Pemphigoid. (28355425)
2017
18
An open, multicenter, randomized clinical study in patients with bullous pemphigoid comparing methylprednisolone and azathioprine with methylprednisolone and dapsone. (28494097)
2017
19
Langerhans cells are predominant high affinity immunoglobulin E receptor bearing cells in the epidermis of bullous pemphigoid skin. (27839901)
2017
20
Correlation of Serum Levels of IgE Autoantibodies Against BP180 With Bullous Pemphigoid Disease Activity. (27829102)
2017
21
Positive clinical outcome in a patient with recalcitrant bullous pemphigoid treated with rituximab and intravenous immunoglobulin. (28508388)
2017
22
Successful Treatment of a Bullous Pemphigoid Patient with Rituximab Who Was Refractory to Corticosteroid and Omalizumab Treatments. (28413387)
2017
23
Bullous Pemphigoid Successfully Treated With a Combination Therapy of Plasmapheresis Followed by Intravenous High Dose Immunoglobulin. (28378368)
2017
24
Bullous pemphigoid with IgG autoantibodies to the I+3 subunit of laminin 332 associated with psoriasis vulgaris. (28468743)
2017
25
Photodynamic Therapy Effective for the Treatment of Actinic Keratosis and Basal Cell Carcinoma in Bullous Pemphigoid Patients. (28373119)
2017
26
Successful treatment of bullous pemphigoid with omalizumab as corticosteroid-sparing agent: report of two cases and review of literature. (27357866)
2016
27
An autoimmune bullous dermatosis with clinical, histopathological, and immunological features of bullous pemphigoid and epidermolysis bullosa acquisita in an adult. (26989994)
2016
28
Salivary IgA and IgG antibodies to bullous pemphigoid 180 noncollagenous domain 16a as diagnostic biomarkers in mucous membrane pemphigoid. (26676445)
2016
29
High-Frequency Color Doppler Sonography of Bullous Pemphigoid: Correlation With Histologic Findings. (27371374)
2016
30
Etanercept-induced generalization of chronic, localized, anogenital bullous pemphigoid in a psoriatic patient. (27051819)
2016
31
Correlation of autoantibodies against BP180/BP230 in response to topical corticosteroids in patients with bullous pemphigoid. (27550573)
2016
32
A possible interaction between periostin and CD163+ skin-resident macrophages in pemphigus vulgaris and bullous pemphigoid. (27501402)
2016
33
Bullous pemphigoid and primary biliary cirrhosis, an infrequent association: A case report. (26949192)
2016
34
Diagnostic value of immunohistochemistry on formalin-fixed paraffin-embedded skin biopsy specimens for bullous pemphigoid. (27105821)
2016
35
Cutaneous Exophiala oligosperma Infection in a Patient with Bullous Pemphigoid with a Review of the Literature. (28025758)
2016
36
Late presentation of generalised bullous pemphigoid-like reaction in a patient treated with pembrolizumab for metastatic melanoma. (27170423)
2016
37
Quality of life, depression, anxiety and loneliness in patients with bullous pemphigoid. A case control study. (27828632)
2016
38
Herpes simplex encephalitis without cerebrospinal fluid pleocytosis in a patient with bullous pemphigoid: a case report. (27247185)
2016
39
Pyodermatitis vegetans with antibodies to bullous pemphigoid antigen 180. (27914095)
2016
40
Bullous Pemphigoid with Lymphocytic Colitis: A Case Report and Short Literature Review. (27469343)
2016
41
Case of bullous pemphigoid in a 28-year-old woman affected by tuberous sclerosis complex. (27400884)
2016
42
Dipeptidyl peptidase-IV inhibitors induced bullous pemphigoid: a case report and analysis of cases reported in the European pharmacovigilance database. (27191539)
2016
43
Combination therapy of prednisolone and i.v. immunoglobulin treatment decreases circulating interleukin-5 and eosinophils in a patient with bullous pemphigoid. (27154738)
2016
44
Disease stabilization with pembrolizumab for metastatic acral melanoma in the setting of autoimmune bullous pemphigoid. (27096097)
2016
45
Bullous pemphigoid-like skin blistering disease in a rhesus macaque (Macaca mulatta). (27373989)
2016
46
A Potential Link between Amyotrophic Lateral Sclerosis and Bullous Pemphigoid: Six New Cases and a Systematic Review of the Literature. (27477403)
2016
47
Direct Immunofluorescence Findings in Discoid Lupus Erythematosus and Bullous Pemphigoid. (26981743)
2016
48
Disseminated acantholytic acanthomas in a patient with bullous pemphigoid. (28007675)
2016
49
Bullous pemphigoid triggered by radiotherapy for breast cancer. (27818063)
2016
50
Bullous pemphigoid developed in a patient with prurigo nodularis. (27511319)
2016

Variations for Bullous Pemphigoid

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Expression for genes affiliated with Bullous Pemphigoid

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Search GEO for disease gene expression data for Bullous Pemphigoid.

Pathways for genes affiliated with Bullous Pemphigoid

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Pathways related to Bullous Pemphigoid according to GeneCards Suite gene sharing:

(show all 24)
idSuper pathwaysScoreTop Affiliating Genes
19.8DSG1, HLA-DQB1, HLA-DRB1
29.8COL17A1, ITGA6, ITGB4
39.6CCL11, DSP, IL5
49.5DSP, ITGA6, ITGB4, PLEC
59.5HLA-DQB1, HLA-DRB1, IL5, ITGA6
69.4LAMA3, LAMB3, LAMC2
79.4LAMA3, LAMB3, LAMC2
8
Show member pathways
9.3DSG1, DSG3, DSP, PLEC
99.1ITGA6, LAMA3, LAMB3, LAMC2
109.1ITGB4, IVL, LAMA3
11
Show member pathways
9.0CCL11, HLA-DQB1, HLA-DRB1, IL5, RNASE3
12
Show member pathways
9.0DSP, DST, EVPL, PLEC, PPL
138.9ITGA6, ITGB4, LAMA3, LAMB3, LAMC2
14
Show member pathways
8.9ITGA6, ITGB4, LAMA3, LAMB3, LAMC2
15
Show member pathways
8.9ITGA6, ITGB4, LAMA3, LAMB3, LAMC2
16
Show member pathways
8.9ITGA6, ITGB4, LAMA3, LAMB3, LAMC2
17
Show member pathways
8.9ITGA6, ITGB4, LAMA3, LAMB3, LAMC2
18
Show member pathways
8.9ITGA6, ITGB4, LAMA3, LAMB3, LAMC2
19
Show member pathways
8.7HLA-DQB1, HLA-DRB1, ITGA6, LAMA3, LAMB3, LAMC2
20
Show member pathways
8.4CD79A, COL17A1, ITGA6, ITGB4, LAMA3, LAMB3
21
Show member pathways
8.2COL17A1, DST, ITGA6, ITGB4, LAMA3, LAMB3
22
Show member pathways
8.2COL17A1, DST, ITGA6, ITGB4, LAMA3, LAMB3
23
Show member pathways
8.2COL17A1, DST, ITGA6, ITGB4, LAMA3, LAMB3
24
Show member pathways
7.9DSG1, DSG3, DSP, EVPL, IVL, PPL

GO Terms for genes affiliated with Bullous Pemphigoid

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Cellular components related to Bullous Pemphigoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1laminin-5 complexGO:000561010.1LAMA3, LAMB3
2MHC class II protein complexGO:004261310.0HLA-DQB1, HLA-DRB1
3hemidesmosomeGO:00300569.7COL17A1, DST, ITGA6, ITGB4, PLEC
4basement membraneGO:00056049.5COL17A1, DST, ITGA6, LAMA3, LAMB3, LAMC2
5desmosomeGO:00300579.4DSG1, DSG3, DSP, EVPL, PPL
6cornified envelopeGO:00015338.6DSG1, DSG3, DSP, EVPL, IVL, PPL
7cell junctionGO:00300548.6COL17A1, DSG1, DSG3, DSP, DST, EVPL
8extracellular exosomeGO:00700626.6DSG1, DSG3, DSP, DST, EVPL, HLA-DRB1

Biological processes related to Bullous Pemphigoid according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIGO:000250410.8HLA-DQB1, HLA-DRB1
2intermediate filament cytoskeleton organizationGO:004510410.7DSP, DST
3amelogenesisGO:009718610.7ITGA6, ITGB4
4humoral immune response mediated by circulating immunoglobulinGO:000245510.7HLA-DQB1, HLA-DRB1
5immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.7HLA-DQB1, HLA-DRB1
6nail developmentGO:003587810.6ITGA6, ITGB4
7cell-matrix adhesionGO:000716010.5COL17A1, ITGA6, ITGB4
8integrin-mediated signaling pathwayGO:000722910.5DST, ITGA6, ITGB4
9single organismal cell-cell adhesionGO:001633710.3DSG1, DSP, ITGA6
10extracellular matrix disassemblyGO:002261710.0LAMA3, LAMB3, LAMC2
11skin developmentGO:00435889.8DSP, ITGA6, ITGB4
12extracellular matrix organizationGO:00301989.5ITGA6, ITGB4, LAMA3, LAMB3, LAMC2
13keratinocyte differentiationGO:00302169.4DSP, EVPL, IVL
14peptide cross-linkingGO:00181499.4DSP, EVPL, IVL
15hemidesmosome assemblyGO:00315819.1COL17A1, ITGA6, ITGB4, LAMA3, LAMB3, LAMC2
16epidermis developmentGO:00085449.0COL17A1, DSP, EVPL, LAMA3, LAMB3, LAMC2
17cornificationGO:00702688.6DSG1, DSG3, DSP, EVPL, IVL, PPL
18keratinizationGO:00314248.5DSG1, DSG3, DSP, EVPL, IVL, PPL
19cell adhesionGO:00071558.3CCL11, DSG1, DSG3, DST, ITGA6, ITGB4

Molecular functions related to Bullous Pemphigoid according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:003239510.7HLA-DQB1, HLA-DRB1
2insulin-like growth factor I bindingGO:003199410.6ITGA6, ITGB4
3neuregulin bindingGO:003813210.6ITGA6, ITGB4
4cadherin bindingGO:00452969.7EVPL, ITGA6, PLEC, PPL
5protein binding, bridgingGO:00306749.4DSP, EVPL, IVL
6structural molecule activityGO:00051988.2DSP, EVPL, IVL, LAMA3, LAMB3

Sources for Bullous Pemphigoid

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet