MCID: BRN009
MIFTS: 56

Burning Mouth Syndrome

Categories: Rare diseases, Oral diseases, Neuronal diseases

Aliases & Classifications for Burning Mouth Syndrome

MalaCards integrated aliases for Burning Mouth Syndrome:

Name: Burning Mouth Syndrome 12 72 49 55 41 14 69
Stomatodynia 49 55 69
Stomatopyrosis 12 55
Orodynia 12 55
Bms 49 55
Burning Mouth Disorder 49
Oral Dysesthesia 55

Classifications:

Orphanet: 55  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:4331
MeSH 41 D002054
NCIt 46 C62545
SNOMED-CT 64 111349000 399165002
Orphanet 55 ORPHA353253
UMLS via Orphanet 70 C0006430 C2930806
ICD10 via Orphanet 33 K14.6

Summaries for Burning Mouth Syndrome

NIH Rare Diseases : 49 Burning mouth syndrome is characterized by long-lasting burning sensations of the mouth. The pain may affect the tongue, gums, lips, palate, throat, or the entire mouth. Burning mouth syndrome may be primary or secondary. Experts believe that the primary form may be caused by damage to the nerves that control pain and taste. The secondary form is caused by an underlying medical condition. In many cases, the underlying cause in unknown. Treatment depends on the symptoms present and aims to control them. Last updated: 3/28/2016

MalaCards based summary : Burning Mouth Syndrome, also known as stomatodynia, is related to glossitis and burns, and has symptoms including oral manifestations An important gene associated with Burning Mouth Syndrome is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Akt Signaling and PAK Pathway. The drugs Clonazepam and Anticonvulsants have been mentioned in the context of this disorder. Affiliated tissues include tongue, testes and brain, and related phenotypes are behavior/neurological and cardiovascular system

Wikipedia : 72 Burning mouth syndrome (BMS) is a burning sensation in the mouth with no underlying dental or medical... more...

Related Diseases for Burning Mouth Syndrome

Diseases in the Burning Mouth Syndrome family:

Burning Mouth Syndrome Type 3

Diseases related to Burning Mouth Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 276)
# Related Disease Score Top Affiliating Genes
1 glossitis 32.3 IL6 TNF
2 burns 31.8 IL1B TNF
3 autonomic nervous system disease 30.0 NGF TAC1
4 trigeminal neuralgia 29.9 SCN9A TRPV1
5 aphthous stomatitis 29.5 IL1B IL6 TNF
6 contact dermatitis 29.5 IL1B IL6 TNF
7 paine syndrome 28.0 IL1B NGF SCN9A TAC1 TRPV1
8 burning mouth syndrome type 3 12.4
9 glossodynia 11.4
10 episodic pain syndrome, familial, 1 10.6
11 extramedullary plasmacytoma 10.4 IL2 IL6
12 immune suppression 10.4 IL2 IL6
13 capillary leak syndrome 10.4 IL2 IL6
14 necrotizing fasciitis 10.4 IL2 IL6
15 scorpion envenomation 10.3 IL6 TNF
16 angioimmunoblastic lymphadenopathy with dysproteinemia 10.3 IL6 TNF
17 critical limb ischemia 10.3 IL6 TNF
18 lesion of sciatic nerve 10.3 NGF TRPV1
19 oral tuberculosis 10.3 IL2 TNF
20 null-cell leukemia 10.3 IL6 TNF
21 cough variant asthma 10.3 NGF TRPV1
22 retinitis pigmentosa 55 10.3 IL6 TNF
23 anterior uveitis 10.3 IL6 TNF
24 autoimmune myocarditis 10.3 IL2 TNF
25 posterior urethral valves 10.3 IL6 TNF
26 meconium aspiration syndrome 10.3 IL6 TNF
27 sciatic neuropathy 10.3 NGF TRPV1
28 farmer's lung 10.3 IL2 TNF
29 louse-borne relapsing fever 10.3 IL6 TNF
30 clonorchiasis 10.3 IL2 TNF
31 listeriosis 10.3 IL6 TNF
32 crimean-congo hemorrhagic fever 10.3 IL6 TNF
33 transverse myelitis 10.3 IL6 TNF
34 ischemic heart disease 10.3 IL6 TNF
35 monoclonal gammopathy of uncertain significance 10.3 IL6 TNF
36 post-transplant lymphoproliferative disease 10.3 IL6 TNF
37 hemorrhagic fever 10.3 IL6 TNF
38 recurrent corneal erosion 10.3 IL1B IL6
39 posterior uveitis 10.3 IL2 TNF
40 myelitis 10.3 IL6 TNF
41 bagassosis 10.3 IL1B IL6
42 nonalcoholic steatohepatitis 10.3 IL6 TNF
43 stromal keratitis 10.3 IL6 TNF
44 neuroschistosomiasis 10.3 NGF TAC1
45 aspiration pneumonia 10.3 TAC1 TRPV1
46 periodontitis, chronic 10.3 IL1B IL6
47 coccidiosis 10.3 IL2 TNF
48 prurigo nodularis 10.3 NGF TAC1
49 cytomegalovirus infection 10.2 IL6 TNF
50 funisitis 10.2 IL1B IL6

Graphical network of the top 20 diseases related to Burning Mouth Syndrome:



Diseases related to Burning Mouth Syndrome

Symptoms & Phenotypes for Burning Mouth Syndrome

UMLS symptoms related to Burning Mouth Syndrome:


oral manifestations

MGI Mouse Phenotypes related to Burning Mouth Syndrome:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.87 NGF SCN9A TAC1 TNF TRPV1 IL2
2 cardiovascular system MP:0005385 9.8 NGF TAC1 TNF TRPV1 IL1B IL2
3 growth/size/body region MP:0005378 9.7 IL6 NGF SCN9A TNF IL1B TRPV1
4 integument MP:0010771 9.5 NGF SCN9A TAC1 TNF TRPV1 IL1B
5 neoplasm MP:0002006 9.02 TNF TRPV1 IL1B IL2 IL6

Drugs & Therapeutics for Burning Mouth Syndrome

Drugs for Burning Mouth Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 73)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clonazepam Approved, Illicit Phase 4,Early Phase 1 1622-61-3 2802
2 Anticonvulsants Phase 4,Early Phase 1
3 GABA Agents Phase 4,Early Phase 1
4 GABA Modulators Phase 4,Early Phase 1
5 Neurotransmitter Agents Phase 4,Phase 2,Early Phase 1
6
Acetylcholine Approved Phase 2 51-84-3 187
7
Bupivacaine Approved, Investigational Phase 2 38396-39-3, 2180-92-9 2474
8 abobotulinumtoxinA Phase 2
9 Botulinum Toxins Phase 2
10 Botulinum Toxins, Type A Phase 2
11 Cholinergic Agents Phase 2
12 Neuromuscular Agents Phase 2
13 onabotulinumtoxinA Phase 2
14 Peripheral Nervous System Agents Phase 2
15 Pharmaceutical Solutions Phase 2
16 Angiogenesis Inhibitors Phase 2
17 Angiogenesis Modulating Agents Phase 2
18 Anti-Bacterial Agents Phase 2
19 Anti-Infective Agents Phase 2
20 Immunosuppressive Agents Phase 2
21 Central Nervous System Depressants Phase 2
22 Anesthetics Phase 2
23 Anesthetics, Local Phase 2
24
Hydroxocobalamin Approved 13422-51-0 5460373 44475014 11953898
25
Iron Approved 7439-89-6 23925
26
Glycerol Approved, Investigational 56-81-5 753
27
Tolnaftate Approved, Investigational, Vet_approved Early Phase 1 2398-96-1 5510
28
Capsaicin Approved 404-86-4 1548943
29
gamma-Aminobutyric acid Approved, Investigational 56-12-2 119
30
Lidocaine Approved, Vet_approved 137-58-6 3676
31
Lorazepam Approved 846-49-1 3958
32
Nalbuphine Approved 20594-83-6 5311304 5360630
33
Naloxone Approved, Vet_approved 465-65-6 5284596
34
Cyanocobalamin Approved, Nutraceutical 68-19-9 44176380
35
Folic Acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
36
leucovorin Approved, Nutraceutical 58-05-9 143 6006
37
Melatonin Approved, Nutraceutical, Vet_approved 73-31-4 896
38
Glutamic Acid Approved, Nutraceutical 56-86-0 33032
39
Butyric Acid Experimental, Investigational 107-92-6 264
40 Antibodies
41 Autoantibodies
42 Hematinics
43 Immunoglobulins
44 Micronutrients
45 Trace Elements
46 Vitamin B 12
47 Vitamin B Complex
48 Vitamins
49 Carboxymethylcellulose Sodium
50 Antioxidants

Interventional clinical trials:

(show all 20)

# Name Status NCT ID Phase Drugs
1 Effectiveness of Mucolox® and Clonazepam in Treatment of Burning Mouth Syndrome Not yet recruiting NCT02690844 Phase 4 Clonazepam mixed with Mucolox®;Mucolox® alone;Clonazepam
2 Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders Completed NCT00374673 Phase 3
3 Botulinum Toxin in Burning Mouth Syndrome Completed NCT02964728 Phase 2 Botulinum Neurotoxin Type A
4 Thalidomide to Treat Oral Lesions in HIV-Infected Patients Completed NCT00001524 Phase 2 Thalidomide
5 Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain Terminated NCT01584947 Phase 2 Bupivacaine;Placebo
6 HLA-DRB1 and HLA-DQB1 Genotyping for Autoantibody-positive and -Negative Patients With Atrophic Glossitis or Burning Mouth Syndrome Unknown status NCT01931293
7 Effect of Gluten Free Diet in Patients With Burning Mouth Syndrome Unknown status NCT01867151
8 Burning Mouth Disorder (BMD) - A Neuropathic Pain Disorder Unknown status NCT00504387
9 The Role of Xerostomia in Burning Mouth Syndrome: Case - Control Study Completed NCT01754740 Uréia;Placebo
10 Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN) Completed NCT02686359
11 Efficacy of Melatonin in Burning Mouth Syndrome (BMS) Completed NCT02580734
12 Acupuncture Versus Clonazepam in Burning Mouth Syndrome Completed NCT02382029 Early Phase 1 Clonazepam
13 A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome Completed NCT00862576
14 Study Evaluating the Laser Diode Effect Burning Mouth Syndrome Completed NCT02757612
15 Neurogenic Mechanisms in Burning Mouth Syndrome Completed NCT00875537
16 Alpha Lipoic Acid for Burning Mouth Completed NCT00387543
17 Pain and Sensory Changes Assessment in HIV+ Patients Completed NCT00422695
18 Evaluation and Treatment of Oral Soft Tissue Diseases Completed NCT00001601
19 Assessment of Peripheral GABA Receptors for Local Pain Relief Recruiting NCT02928328 GABA oral solution;Intramuscular GABA;Pain modulation
20 Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain Terminated NCT00716807 nalbuphine plus naloxone;nalbuphine plus placebo;nalbuphine plus naloxone;nalbuphine plus placebo

Search NIH Clinical Center for Burning Mouth Syndrome

Cochrane evidence based reviews: burning mouth syndrome

Genetic Tests for Burning Mouth Syndrome

Anatomical Context for Burning Mouth Syndrome

MalaCards organs/tissues related to Burning Mouth Syndrome:

38
Tongue, Testes, Brain, Thyroid, Skin, Colon, Cortex

Publications for Burning Mouth Syndrome

Articles related to Burning Mouth Syndrome:

(show top 50) (show all 480)
# Title Authors Year
1
Is burning mouth syndrome a neuropathic pain condition? ( 29257770 )
2018
2
Plasma IL-8 signature correlates with pain and depressive symptomatology in patients with burning mouth syndrome: Results from a pilot study. ( 29194773 )
2018
3
Management of reticular oral lichen planus patients with burning mouth syndrome-like oral symptoms: a pilot study. ( 29308937 )
2018
4
The role of psychological factors in the development of burning mouth syndrome. ( 29074062 )
2018
5
Plasma N-acylethanolamine and endocannabinoid levels in burning mouth syndrome: potential role in disease pathogenesis. ( 29436743 )
2018
6
Clinical characterization of women with burning mouth syndrome in a case-control study. ( 29284330 )
2017
7
Burning Mouth Syndrome: Aetiopathogenesis and Principles of Management. ( 29180911 )
2017
8
Burning mouth syndrome. ( 28569120 )
2017
9
The Significance of Brain Transcranial Sonography in Burning Mouth Syndrome: a Pilot Study. ( 28740270 )
2017
10
"Is it Sjogren's syndrome or burning mouth syndrome? Distinct pathoses with similar oral symptoms"-a commentary. ( 29217136 )
2017
11
Burning mouth syndrome: a systematic review of treatments. ( 28247977 )
2017
12
Effects of low-level laser therapy on burning mouth syndrome. ( 27893167 )
2017
13
The association between Burning Mouth Syndrome and Sleep Disturbance: a case-control multicentre study. ( 29156085 )
2017
14
Comparison of Salivary Cortisol and I+-amylase Levels and Psychological Profiles in Patients with Burning Mouth Syndrome. ( 28112423 )
2017
15
Relationships between oral MUC1 expression and salivary hormones in burning mouth syndrome. ( 28199919 )
2017
16
A case-control evaluation of fungiform papillae density in burning mouth syndrome. ( 28833164 )
2017
17
Is it SjAPgren's syndrome or burning mouth syndrome? Distinct pathoses with similar oral symptoms. ( 28283095 )
2017
18
A A9burningA9 therapy for burning mouth syndrome: preliminary results with the administration of topical capsaicin. ( 28691458 )
2017
19
"Is it SjAPgren's syndrome or burning mouth syndrome? Distinct pathoses with similar oral symptoms"-Response. ( 29153276 )
2017
20
Topical Clonazepam Solution for the Management of Burning Mouth Syndrome: A Retrospective Study. ( 28738111 )
2017
21
Profiling intraoral neuropathic disturbances following lingual nerve injury and in burning mouth syndrome. ( 28330489 )
2017
22
A diagnostic and therapeutic approach to primary burning mouth syndrome. ( 28916026 )
2017
23
Functional Alterations of Postcentral Gyrus Modulated by Angry Facial Expressions during Intraoral Tactile Stimuli in Patients with Burning Mouth Syndrome: A Functional Magnetic Resonance Imaging Study. ( 29163243 )
2017
24
Online Information on the Treatment of Burning Mouth Syndrome: Quality and Readability. ( 28437511 )
2017
25
Little evidence to support or refute interventions for the management of burning mouth syndrome. ( 28642559 )
2017
26
Pain-relieving effects of clonazepam and amitriptyline in burning mouth syndrome: a retrospective study. ( 28473243 )
2017
27
Neuropathic Pain in Patients with Burning Mouth Syndrome Evaluated Using painDETECT. ( 28057813 )
2017
28
Effect of Oral Care Gel for Burning Mouth Syndrome in a Patient with Hepatitis C: A Case Report. ( 29033766 )
2017
29
RF-Burning Mouth Syndrome: New Treatments. ( 27702434 )
2017
30
Evaluating Burning Mouth Syndrome as a Comorbidity of Atypical Odontalgia: The Impact on Pain Experiences. ( 28972293 )
2017
31
Potential protein biomarkers for burning mouth syndrome discovered by quantitative proteomics. ( 28326926 )
2017
32
Analgesic effect of topical oral capsaicin gel in burning mouth syndrome. ( 28007005 )
2017
33
Refractory burning mouth syndrome: clinical and paraclinical evaluation, comorbiities, treatment and outcome. ( 28357703 )
2017
34
Chronic Orofacial Pain: Burning Mouth Syndrome and Other Neuropathic Disorders. ( 28638895 )
2017
35
Primary burning mouth syndrome: Literature review and preliminary findings suggesting possible association with pain modulation. ( 29192294 )
2017
36
Burning mouth syndrome: results of screening tests for vitamin and mineral deficiencies, thyroid hormone, and glucose levels-experience at Mayo Clinic over a decade. ( 28436021 )
2017
37
Botulinum Toxin for Burning Mouth Syndrome. ( 28395302 )
2017
38
Altered structural connectivity of pain-related brain network in burning mouth syndrome-investigation by graph analysis of probabilistic tractography. ( 28361345 )
2017
39
Taste function assessed by electrogustometry in burning mouth syndrome: a case control study. ( 28029722 )
2016
40
The Detection of Small-Fiber Neuropathies in Burning Mouth Syndrome and Iatrogenic Lingual Nerve Injuries: Use of Quantitative Sensory Testing. ( 27128472 )
2016
41
An overview of burning mouth syndrome. ( 26709657 )
2016
42
Burning mouth syndrome. ( 26745781 )
2016
43
Opiorphin levels in fluids of burning mouth syndrome patients: a case-control study. ( 27834029 )
2016
44
Combined Acupuncture and Auriculotherapy in Burning Mouth Syndrome Treatment: A Preliminary Single-Arm Clinical Trial. ( 27585312 )
2016
45
Low-dose aripiprazole for refractory burning mouth syndrome. ( 27279742 )
2016
46
Primary Burning Mouth Syndrome: A Questionnaire Study of Neuropathic and Psychological Components. ( 26691521 )
2016
47
Opiorphin in burning mouth syndrome patients: a case-control study. ( 28013436 )
2016
48
Impact of reassurance on pain perception in patients with primary burning mouth syndrome. ( 27101802 )
2016
49
The relationship between the clinical features of idiopathic burning mouth syndrome and self-perceived quality of life. ( 28025430 )
2016
50
Burning Mouth Syndrome: A Review of the Etiopathologic Factors and Management. ( 27207008 )
2016

Variations for Burning Mouth Syndrome

Expression for Burning Mouth Syndrome

Search GEO for disease gene expression data for Burning Mouth Syndrome.

Pathways for Burning Mouth Syndrome

Pathways related to Burning Mouth Syndrome according to GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.24 IL1B IL2 IL6 NGF TNF
2
Show member pathways
13.14 IL1B IL2 IL6 NGF TNF
3
Show member pathways
12.83 IL2 IL6 NGF TNF
4
Show member pathways
12.72 IL1B IL2 IL6 TNF
5
Show member pathways
12.67 IL1B IL2 IL6 TNF
6
Show member pathways
12.48 IL1B IL2 IL6 TNF
7
Show member pathways
12.47 IL1B IL2 IL6 TNF
8
Show member pathways
12.45 IL1B IL2 IL6 NGF TNF
9
Show member pathways
12.41 IL1B IL2 IL6 TNF
10
Show member pathways
12.32 IL1B IL2 IL6 TNF
11 12.3 IL2 IL6 TNF
12
Show member pathways
12.21 IL1B IL6 TNF
13
Show member pathways
12.2 IL1B IL2 IL6 TNF
14
Show member pathways
12.16 IL1B IL6 TNF
15 12.12 IL1B IL6 TNF
16
Show member pathways
12.08 IL1B IL6 TNF
17 11.91 IL2 IL6 TNF
18
Show member pathways
11.91 IL1B IL2 IL6 TNF
19 11.9 IL1B IL6 TNF
20 11.87 IL1B IL6 TNF
21 11.83 IL1B IL6 TNF
22 11.81 IL1B IL6 TNF
23 11.8 IL1B IL6 TNF
24 11.77 IL1B IL6 TNF
25 11.75 IL1B IL2 IL6 TNF
26 11.71 IL1B IL2 TNF
27 11.67 IL1B IL6 TNF
28
Show member pathways
11.64 IL1B IL2 IL6 TNF
29 11.59 IL1B IL6 TNF
30 11.57 IL1B IL6 NGF TAC1 TNF
31 11.51 IL1B IL6 TNF
32 11.48 IL2 IL6 TNF
33 11.45 IL1B IL6 TNF
34 11.44 IL1B IL6 TNF
35 11.43 IL1B IL2 IL6 TNF
36 11.42 IL1B IL2 TNF
37 11.38 IL1B IL6 TNF
38
Show member pathways
11.27 IL2 TNF
39 11.26 IL1B IL6
40
Show member pathways
11.26 IL1B IL2 IL6 TNF
41 11.23 IL1B IL6 TNF
42 11.21 NGF TNF
43 11.21 NGF TRPV1
44 11.21 IL1B IL6 TNF
45 11.16 IL1B IL6 TNF
46 11.12 IL1B IL6 TNF
47 11.06 IL1B IL2 IL6 TNF
48 11.04 IL1B TNF
49 11.04 IL6 TNF
50 10.96 IL6 TNF

GO Terms for Burning Mouth Syndrome

Cellular components related to Burning Mouth Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 IL1B IL2 IL6 NGF TAC1 TNF

Biological processes related to Burning Mouth Syndrome according to GeneCards Suite gene sharing:

(show all 40)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.93 IL1B IL2 IL6 TNF
2 positive regulation of gene expression GO:0010628 9.87 IL1B IL6 NGF TNF
3 MAPK cascade GO:0000165 9.86 IL1B IL2 TNF
4 positive regulation of apoptotic process GO:0043065 9.85 IL6 NGF TNF TRPV1
5 positive regulation of protein phosphorylation GO:0001934 9.82 IL1B IL2 TNF
6 cell-cell signaling GO:0007267 9.81 IL1B IL2 NGF TAC1
7 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.8 IL1B IL6 TNF
8 positive regulation of cytosolic calcium ion concentration GO:0007204 9.79 IL2 TAC1 TRPV1
9 positive regulation of DNA binding transcription factor activity GO:0051091 9.75 IL1B IL6 TNF
10 cellular response to nerve growth factor stimulus GO:1990090 9.68 TAC1 TRPV1
11 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.68 IL1B TNF
12 lipopolysaccharide-mediated signaling pathway GO:0031663 9.67 IL1B TNF
13 positive regulation of phagocytosis GO:0050766 9.67 IL1B TNF
14 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.67 IL1B IL2
15 extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 9.66 NGF TNF
16 positive regulation of interleukin-8 production GO:0032757 9.66 IL1B TNF
17 positive regulation of NF-kappaB import into nucleus GO:0042346 9.65 IL1B TNF
18 response to pain GO:0048265 9.65 TAC1 TRPV1
19 positive regulation of chemokine production GO:0032722 9.65 IL6 TNF
20 negative regulation of lipid catabolic process GO:0050995 9.64 IL1B TNF
21 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.63 IL1B TNF
22 positive regulation of T cell proliferation GO:0042102 9.63 IL1B IL2 IL6
23 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.62 IL1B TNF
24 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.61 IL1B TNF
25 positive regulation of acute inflammatory response GO:0002675 9.6 IL6 TAC1
26 positive regulation of immunoglobulin secretion GO:0051024 9.59 IL2 IL6
27 behavioral response to pain GO:0048266 9.58 SCN9A TRPV1
28 sensory perception of pain GO:0019233 9.58 SCN9A TAC1 TRPV1
29 negative regulation of lipid storage GO:0010888 9.56 IL6 TNF
30 positive regulation of chemokine biosynthetic process GO:0045080 9.54 IL1B TNF
31 positive regulation of interleukin-6 production GO:0032755 9.54 IL1B IL6 TNF
32 regulation of establishment of endothelial barrier GO:1903140 9.52 IL1B TNF
33 fever generation GO:0001660 9.49 IL1B TRPV1
34 positive regulation of fever generation GO:0031622 9.48 IL1B TNF
35 sequestering of triglyceride GO:0030730 9.43 IL1B TNF
36 positive regulation of interferon-gamma production GO:0032729 9.43 IL1B IL2 TNF
37 regulation of receptor activity GO:0010469 9.35 IL1B IL2 IL6 NGF TNF
38 positive regulation of nitric oxide biosynthetic process GO:0045429 9.33 IL1B TNF TRPV1
39 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.32 IL1B TNF
40 inflammatory response GO:0006954 9.1 IL1B IL6 SCN9A TAC1 TNF TRPV1

Molecular functions related to Burning Mouth Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.13 IL2 IL6 NGF
2 cytokine activity GO:0005125 8.92 IL1B IL2 IL6 TNF

Sources for Burning Mouth Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....