BMS
MCID: BRN009
MIFTS: 59

Burning Mouth Syndrome (BMS) malady

Rare diseases, Oral diseases categories
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Summaries for Burning Mouth Syndrome

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43NIH Rare Diseases, 65Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Burning mouth syndrome is characterized by long-lasting burning sensations of the mouth. the pain may affect the tongue, lips, palate, or throughout the mouth. allergies, nerve damage, irritation, stress, among other things can cause burning mouth syndrome, however in many cases the underlying cause can not be identified. the condition may respond to interventions and treatments, may resolve spontaneously, or may persist for months to years.  last updated: 11/12/2010

MalaCards: Burning Mouth Syndrome, also known as stomatodynia, is related to neuropathy and parkinson's disease. An important gene associated with Burning Mouth Syndrome is CD14 (CD14 molecule), and among its related pathways are IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types and LDL Oxidation in Atherogenesis. The compounds muramyl dipeptide and rantes have been mentioned in the context of this disorder. Affiliated tissues include tongue, testes and heart, and related mouse phenotypes are adipose tissue and liver/biliary system.

Wikipedia:65 Burning mouth syndrome (BMS also termed glossodynia,orodynia,oral... more...

Aliases & Classifications for Burning Mouth Syndrome

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8Disease Ontology, 43NIH Rare Diseases, 62UMLS, 35MeSH, 58SNOMED-CT, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Oral diseases


Aliases & Descriptions:

burning mouth syndrome 8 43 62
stomatodynia 43 62
burning mouth disorder 43
stomatopyrosis 8
orodynia 8
bms 43


External Ids:

Disease Ontology8 DOID:4331
MeSH35 D002054
NCIt40 C62545

Related Diseases for Burning Mouth Syndrome

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17GeneCards, 18GeneDecks
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Diseases in the Burning Mouth Syndrome family:

Burning Mouth Syndrome Type 3

Diseases related to Burning Mouth Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 162)
idRelated DiseaseScoreTop Affiliating Genes
1neuropathy30.6NGF, SCN9A, TAC1, TRPV1
2parkinson's disease30.4NGF, TAC1, SLC6A4
3pain disorder30.3NGF, TAC1, SCN9A
4eosinophilia30.0NGF, IL2, CD14
5diabetes mellitus29.9TNF, TF, NGF, IL1B, IL6, TAC1
6myeloma29.8CD14, IL1B, IL2, IL6
7vascular disease29.6TNF, NGF, IL6, IL1B, TF, IL2
8leukemia29.6TLR2, TNF, CD14, IL2, IL6, NGF
9burns11.4
10blindness10.6
11glossodynia10.5
12lichen planus10.5
13burning mouth syndrome type 310.5
14oral lichen planus10.4
15oral submucous fibrosis10.3
16trigeminal neuralgia10.3
17atrophic glossitis10.3
18glossitis10.3
19aplastic anemia10.2
20hemophilia10.2
21hemophilia b10.2
22endotheliitis10.2
23alexithymia10.1
24aphthous stomatitis10.1
25type 1 diabetes mellitus10.1
26restless legs syndrome10.1
27contact dermatitis10.1
28dermatitis10.1
29hypothyroidism10.1
30mood disorder10.1
31peripheral neuropathy10.1
32personality disorder10.1
33stomatitis10.1
34thyroiditis10.1
35urticaria10.1
36vitamin b12 deficiency10.1
37complex regional pain syndrome10.1TAC1
38pulpitis10.1TRPV1
39corneal ulcer10.1NGF
40serotonin syndrome10.1TAC1
41tularemia10.1TLR2
42capillary leak syndrome10.1IL2
43degenerative disc disease10.1IL1B
44low compliance bladder10.1NGF, P2RX3
45diabetic neuropathy10.1TRPV1, NGF
46coronary thrombosis10.1
47leprosy10.1IL2, TLR2
48lepromatous leprosy10.1TLR2, IL2
49fibromyalgia10.1SLC6A4, TAC1
50constipation10.1TAC1, SLC6A4

Graphical network of the top 20 diseases related to Burning Mouth Syndrome:



Diseases related to burning mouth syndrome

Symptoms for Burning Mouth Syndrome

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Drugs & Therapeutics for Burning Mouth Syndrome

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Burning Mouth Syndrome

Search NIH Clinical Center for Burning Mouth Syndrome

Genetic Tests for Burning Mouth Syndrome

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Anatomical Context for Burning Mouth Syndrome

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33MalaCards
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MalaCards organs/tissues related to Burning Mouth Syndrome:

33
Tongue, Testes, Heart, Colon, Thyroid, Skin

Animal Models for Burning Mouth Syndrome or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Burning Mouth Syndrome:

37 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.6TLR2, TNF, IL6, CD14, TRPV1
2MP:00053708.4TLR2, TNF, IL2, IL6, TRPV1
3MP:00053908.3CD14, IL1B, IL6, TNF, TLR2
4MP:00053698.3TLR2, NGF, TNF, IL6, SLC6A4
5MP:00020068.2TLR2, TNF, IL2, IL6, IL1B, TRPV1
6MP:00053798.0TLR2, TNF, IL2, IL6, SLC6A4
7MP:00053887.8TLR2, TNF, P2RX3, IL2, IL6, CD14
8MP:00053977.6TF, TLR2, TNF, IL2, IL6, IL1B
9MP:00053787.3TF, TLR2, NGF, TNF, IL2, IL6
10MP:00053877.1TLR2, TNF, P2RX3, IL2, IL6, IL1B
11MP:00036316.7TLR2, NGF, TNF, SCN9A, P2RX3, IL6
12MP:00107716.7TLR2, NGF, TNF, SCN9A, P2RX3, IL6
13MP:00053866.4SCN9A, TNF, NGF, TLR2, P2RX3, IL2
14MP:00053856.3TRPV1, TLR2, NGF, TNF, P2RX3, IL2
15MP:00053766.1TF, TLR2, NGF, TNF, P2RX3, IL2
16MP:00107686.0TNF, NGF, TLR2, TF, SCN9A, P2RX3

Publications for Burning Mouth Syndrome

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52PubMed
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Articles related to Burning Mouth Syndrome:

(show top 50)    (show all 353)
idTitleAuthorsYear
1
Management of burning mouth syndrome: a clinical experience. (24353760)
2013
2
Burning mouth syndrome. (23809306)
2013
3
Burning mouth syndrome and menopause. (23411996)
2013
4
How do I manage a patient with burning mouth syndrome? (23763730)
2013
5
Defining and diagnosing burning mouth syndrome: Perceptions of directors of North American postgraduate oral medicine and orofacial pain programs. (24080929)
2013
6
Burning mouth syndrome. (23429751)
2013
7
Morphological evaluation of tongue mucosa in burning mouth syndrome. (21824605)
2012
8
Zinc-replacement therapy may not reduce oral pain in patients with zinc-deficient burning mouth syndrome (BMS). (22078830)
2011
9
Treatment of burning mouth syndrome with a low-level energy diode laser. (20969436)
2011
10
Risk factors in burning mouth syndrome: a case-control study based on patient records. (20440632)
2011
11
Burning mouth syndrome: correlation of treatment to clinical variables of the disease. (21743413)
2011
12
A case of unilateral burning mouth syndrome of neuropathic origin. (20807251)
2011
13
Burning mouth syndrome. (20690412)
2010
14
Oral pain perception and taste in burning mouth syndrome. (19804504)
2010
15
Correlation between Burning Mouth Syndrome and Anxiety in the Elderly Inmates of Sanitaria in Tehran. (22991594)
2010
16
Burning mouth syndrome: is acupuncture a therapeutic possibility? (20596066)
2010
17
Salivary levels of IL-1beta, IL-6, IL-8, and TNF-alpha in patients with burning mouth syndrome. (19555923)
2009
18
Salivary cortisol, stress and quality of life in patients with burning mouth syndrome. (19453816)
2009
19
Anxiety and salivary cortisol levels in patients with burning mouth syndrome: case-control study. (18329582)
2008
20
Efficacy of moclobemide in burning mouth syndrome: a nonrandomized, open-label study. (18548844)
2008
21
Burning mouth syndrome responsive to pramipexol. (18219443)
2008
22
Burning mouth syndrome as a trigeminal small fibre neuropathy: Increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score. (17582772)
2007
23
Linking allergy to mercury to HLA and burning mouth syndrome. (17714143)
2007
24
Burning mouth syndrome (stomatodynia). (17601771)
2007
25
Management of burning mouth syndrome: systematic review and management recommendations. (17379153)
2007
26
Detection of salivary interleukin 2 and interleukin 6 in patients with burning mouth syndrome. (16864905)
2006
27
Burning mouth syndrome. Turning down the heat. (17117503)
2006
28
Ciguatera neurotoxin poisoning mimicking burning mouth syndrome. (15997935)
2005
29
Burning mouth syndrome. (16109125)
2005
30
Psychological profile in burning mouth syndrome. (15024358)
2004
31
Recovery from mercury-induced burning mouth syndrome due to mercury allergy. (15473333)
2004
32
Systemic capsaicin for burning mouth syndrome: short-term results of a pilot study. (14720197)
2004
33
Burning mouth syndrome in the Basque Country: a preliminary study of 30 cases. (12618668)
2003
34
Correlations among mood disorder, serum interleukin-2 and interleukin-6 in patients with burning mouth syndrome]. (14650995)
2003
35
Burning mouth syndrome (BMS): double blind controlled study of alpha-lipoic acid (thioctic acid) therapy. (12110042)
2002
36
The secretion of parotid saliva as stimulated by 10% citric acid is not related to precipitating factors in burning mouth syndrome. (11168857)
2001
37
A literature review and pilot study to characterise the treatment of burning mouth syndrome. (11692831)
2001
38
Diagnosis and treatment of burning mouth syndrome. (11404907)
2000
39
Psychiatric comorbidity in patients with burning mouth syndrome. (9625229)
1998
40
Burning mouth syndrome. (9844361)
1998
41
Burning mouth syndrome: a review of etiologies. (9237148)
1997
42
The burning mouth syndrome. (8543701)
1996
43
Burning mouth syndrome. (8762797)
1996
44
Burning mouth syndrome: an update. (7629360)
1995
45
Burning mouth syndrome: an overlooked condition in the geriatric population. Although the health profession has known about BMS for many years, diagnosis and treatment are still difficult. (7926941)
1994
46
Oral medicine in practice: burning mouth syndrome. (2789896)
1989
47
Burning mouth syndrome due to nicotinic acid esters and sorbic acid. (3191688)
1988
48
Pain and personality profiles in burning mouth syndrome. (3822501)
1987
49
Atypical burning mouth syndrome. (3427951)
1987
50
The burning mouth syndrome. Restorative and prosthodontic treatment. (4864535)
1967

Variations for Burning Mouth Syndrome

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Expression for genes affiliated with Burning Mouth Syndrome

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Burning Mouth Syndrome

Search GEO for disease gene expression data for Burning Mouth Syndrome.

Pathways for genes affiliated with Burning Mouth Syndrome

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Sources:
50PathCards, 54R&D Systems, 53QIAGEN, 61Tocris Bioscience, 30KEGG, 12EMD Millipore, 55Reactome, 5Cell Signaling Technology, 38NCBI BioSystems Database, 60Thomson Reuters
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Pathways related to Burning Mouth Syndrome according to GeneCards/GeneDecks:

(show top 50)    (show all 62)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5IL1B, IL6
29.4IL1B, TNF
3
Show member pathways
9.4TLR2, IL2, IL1B
4
Show member pathways
9.3CD14, TNF, TLR2
5
Show member pathways
9.2IL6, IL1B, CD14
6
Show member pathways
9.2IL1B, IL6, TLR2
79.2TLR2, IL6, IL1B
8
Show member pathways
9.2IL1B, IL6, IL2
99.1TNF, IL1B, CD14
10
Show member pathways
9.1NGF, TNF, IL1B
119.1IL1B, TNF, TLR2
129.1TLR2, TNF, IL1B
13
Show member pathways
9.1SCN9A, P2RX3, TRPV1
149.0IL6, TNF, TLR2
159.0IL6, IL2, NGF, TLR2
16
Show member pathways
Serotonin Transporter Activity38
9.0SLC6A4, IL1B, TNF
179.0TNF, IL2, IL6
188.9IL1B, IL6, TNF
198.9IL1B, IL6, TNF
20
Show member pathways
thioredoxin pathway38
8.9TNF, IL6, IL1B
218.9TNF, IL6, IL1B
22
Show member pathways
8.9TNF, IL6, IL1B
23
Show member pathways
MAPK signaling pathway38
8.9CD14, IL1B, TNF, NGF
248.6CD14, IL1B, IL6, TNF
25
Show member pathways
Immune response MIF in innate immunity response60
8.6CD14, IL1B, IL6, TNF
268.6TNF, IL6, IL1B, CD14
278.6TNF, IL6, IL1B, CD14
288.6IL1B, IL6, TNF, TLR2
298.6TLR2, TNF, IL6, IL1B
308.5IL1B, IL6, IL2, TNF
31
Show member pathways
BCR signaling pathway38
TCR Signaling Pathway38
8.5IL1B, IL6, IL2, TNF
328.5IL1B, IL6, IL2, TNF
33
Show member pathways
8.5TNF, IL2, IL6, IL1B
348.5TNF, IL2, IL6, IL1B
35
Show member pathways
8.5P2RX3, IL2, IL6, TRPV1
36
Show member pathways
8.5TLR2, TNF, IL2, IL1B, CD14
37
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
8.3CD14, IL1B, IL6, TNF, TLR2
38
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
8.3TLR2, TNF, IL6, IL1B, CD14
398.3TLR2, TNF, IL6, IL1B, CD14
408.3TLR2, TNF, IL6, IL1B, CD14
418.3TLR2, TNF, IL6, IL1B, CD14
42
Show member pathways
IL23-mediated signaling events38
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling38
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
8.3TNF, IL2, IL6, IL1B, CD14
43
Show member pathways
8.3TNF, IL2, IL6, IL1B, CD14
44
Show member pathways
8.2TLR2, TNF, IL2, IL6, IL1B
45
Show member pathways
IL27-mediated signaling events38
8.2TLR2, TNF, IL2, IL6, IL1B
46
Show member pathways
8.2TLR2, TNF, IL2, IL6, IL1B
47
Show member pathways
8.2TLR2, TNF, IL2, IL6, IL1B
48
Show member pathways
8.2TLR2, TNF, IL2, IL6, IL1B
49
Show member pathways
Toll-like receptor signaling pathway38
Regulation of toll-like receptor signaling pathway38
8.0TLR2, TNF, IL2, IL6, IL1B, CD14
507.3SLC6A4, TF, NGF, TNF, IL6, IL1B

Compounds for genes affiliated with Burning Mouth Syndrome

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Sources:
45Novoseek, 29IUPHAR, 11DrugBank, 61Tocris Bioscience, 24HMDB, 51PharmGKB, 3BitterDB
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Compounds related to Burning Mouth Syndrome according to GeneCards/GeneDecks:

(show top 50)    (show all 177)
idCompoundScoreTop Affiliating Genes
1muramyl dipeptide45 2910.7CD14, IL1B, TLR2
2rantes459.5CD14, IL1B, IL2, TLR2
3bucillamine459.5IL6, IL2, IL1B
4hbd2459.3IL6, TLR2, IL1B
5resiniferatoxin45 2910.2TRPV1, TAC1, P2RX3
6gold sodium thiomalate459.2CD14, IL1B, IL2, TNF
7tenidap45 2910.1TNF, IL1B, IL6
8toxin-1459.1IL1B, IL2, TNF
9anakinra45 1110.1IL6, IL1B, TNF
10vesnarinone459.1TNF, IL6, IL1B
11taurine chloramine458.9IL1B, IL2, TNF, IL6
12il-12458.9IL1B, IL6, IL2, TNF
13poly(i-c)458.9IL6, IL1B, TLR2, TNF
14ccl345 299.9IL6, TNF, TLR2, IL1B
15capsaicin45 299.9P2RX3, NGF, TAC1, TRPV1
16pdtc458.8TNF, IL6, NGF, IL1B
17polymyxin b458.8IL6, IL1B, CD14, TNF, TLR2
18lipoteichoic acid458.8IL6, TLR2, CD14, IL1B, TNF
19peptidoglycan45 299.7TLR2, TNF, IL6, CD14, IL1B
20gm-csf45 299.7CD14, IL1B, IL6, IL2, TNF
21triptolide458.7IL1B, TNF, IL2, IL6, CD14
22pentoxifylline45 119.7IL1B, TNF, IL2, CD14, IL6
23leukotriene b445 61 2410.7IL1B, IL6, TNF, TLR2, TRPV1
24neopterin458.7TNF, IL2, IL6, IL1B, CD14
25endotoxin458.7TNF, TLR2, CD14, IL1B, IL6
26polyinosinic-polycytidylic acid458.7TLR2, IL6, IL1B, IL2, TNF
27il 10458.7IL6, TLR2, TNF, IL2, IL1B
28anisomycin45 119.6NGF, TNF, IL6, IL1B
29epinephrine45 24 1110.6NGF, TAC1, SLC6A4, IL6, TF
30mip 1alpha458.6IL1B, IL6, TNF
31prostacyclin458.5TAC1, IL1B, TF, TNF, NGF
32prednisolone45 29 1110.5NGF, TF, CD14, IL6, IL2, TNF
33norepinephrine45 24 1110.5SLC6A4, CD14, TAC1, IL6, NGF, TF
34sb 20358045 619.4TLR2, TNF, IL1B, IL6, NGF
35thalidomide45 51 61 1111.4IL1B, TNF, IL2, IL6
36herbimycin a45 619.4IL1B, IL6, IL2, TNF, NGF, CD14
37pd 98,059458.4IL1B, IL6, TNF, NGF, TLR2, CD14
38fibrinogen458.4TF, CD14, IL6, TNF, TLR2
39hydrocortisone45 3 61 1111.3TF, IL2, IL6, IL1B, CD14, TNF
40prostaglandin458.2IL1B, TNF, TAC1, TRPV1, TLR2, IL6
41calcitriol45 61 24 1111.1IL2, TLR2, NGF, TNF, IL6, IL1B
42indomethacin45 29 61 1111.1NGF, IL2, TNF, TAC1, IL1B, IL6
43cycloheximide458.1IL6, CD14, IL1B, TLR2, NGF, TNF
44cyclosporin a45 29 619.9TNF, TLR2, NGF, TRPV1, TF, CD14
45actinomycin d457.8TAC1, IL6, IL1B, IL2, TNF, NGF
46vegf457.7IL1B, IL6, IL2, NGF, TNF, TF
47dexamethasone45 51 29 1110.6TLR2, CD14, TNF, TAC1, IL2, IL6
48nitric oxide45 24 119.3TNF, TRPV1, TAC1, IL1B, IL6, P2RX3
49pge2457.2TF, TNF, IL6, IL1B, TAC1, CD14
50histamine45 29 249.2NGF, TLR2, TF, CD14, TAC1, IL1B

GO Terms for genes affiliated with Burning Mouth Syndrome

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Sources:
16Gene Ontology
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Cellular components related to Burning Mouth Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endosome membraneGO:0100089.1SLC6A4, CD14, TF
2external side of plasma membraneGO:0098979.0IL6, TNF, TLR2
3cell surfaceGO:0099868.9CD14, TNF, TLR2, TF
4membrane raftGO:0451218.5TNF, P2RX3, CD14, SLC6A4
5integral component of plasma membraneGO:0058878.0TLR2, TNF, P2RX3, SLC6A4, TRPV1
6extracellular spaceGO:0056157.2CD14, TF, NGF, TNF, IL2, IL6
7extracellular regionGO:0055767.2TF, NGF, TNF, IL2, IL6, IL1B

Biological processes related to Burning Mouth Syndrome according to GeneCards/GeneDecks:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1cellular response to lipoteichoic acidGO:07122310.3TLR2, CD14
2positive regulation of immunoglobulin secretionGO:05102410.0IL2, IL6
3positive regulation of interleukin-18 productionGO:03274110.0TNF, TLR2
4response to electrical stimulusGO:0516029.9IL6, NGF
5positive regulation of tumor necrosis factor productionGO:0327609.9CD14, TLR2
6positive regulation of interleukin-8 productionGO:0327579.9IL1B, TLR2
7response to toxic substanceGO:0096369.9SLC6A4, SCN9A, TLR2
8negative regulation of growth of symbiont in hostGO:0441309.8TNF, TLR2
9extrinsic apoptotic signaling pathway in absence of ligandGO:0971929.8IL1B, IL2, NGF
10sequestering of triglycerideGO:0307309.8IL1B, TNF
11positive regulation of calcidiol 1-monooxygenase activityGO:0605599.8IL1B, TNF
12positive regulation of heterotypic cell-cell adhesionGO:0341169.8TNF, IL1B
13positive regulation of fever generationGO:0316229.8TNF, IL1B
14positive regulation of acute inflammatory responseGO:0026759.8TAC1, IL6
15positive regulation of chemokine biosynthetic processGO:0450809.7TNF, IL1B
16positive regulation of cytokine secretionGO:0507159.7TLR2, TNF, CD14
17regulation of I-kappaB kinase/NF-kappaB signalingGO:0431229.7IL1B, TNF
18positive regulation of membrane protein ectodomain proteolysisGO:0510449.7TNF, IL1B
19epithelial cell proliferation involved in salivary gland morphogenesisGO:0606649.7TNF, IL6
20negative regulation of lipid catabolic processGO:0509959.7IL1B, TNF
21negative regulation of lipid storageGO:0108889.7TNF, IL6
22behavioral response to painGO:0482669.6SCN9A, P2RX3
23neuronal action potentialGO:0192289.6P2RX3, SCN9A
24positive regulation of mitosisGO:0458409.5IL1B, TNF
25response to carbohydrateGO:0097439.5P2RX3, IL1B
26positive regulation of NF-kappaB import into nucleusGO:0423469.5IL1B, TNF, TLR2
27lipopolysaccharide-mediated signaling pathwayGO:0316639.5IL1B, TNF, TLR2
28positive regulation of chemokine productionGO:0327229.5IL6, TNF, TLR2
29positive regulation of interferon-gamma productionGO:0327299.5IL1B, IL2, TNF
30protein kinase B signalingGO:0434919.5IL1B, TNF
31response to lipopolysaccharideGO:0324969.5TAC1, IL6, NGF
32defense response to Gram-positive bacteriumGO:0508309.5TLR2, TNF, IL6
33response to ATPGO:0331989.4P2RX3, IL1B
34response to glucocorticoidGO:0513849.4NGF, TNF, IL6
35negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.3IL1B, TNF
36response to heatGO:0094089.3P2RX3, IL6, CD14
37response to coldGO:0094099.2IL6, P2RX3
38cell-cell signalingGO:0072679.2IL2, IL1B, TAC1
39cellular response to organic cyclic compoundGO:0714079.1IL1B, TNF
40response to drugGO:0424939.1NGF, TNF, IL6, SLC6A4
41positive regulation of sequence-specific DNA binding transcription factor activityGO:0510919.0NGF, TNF, IL6, IL1B
42positive regulation of nitric oxide biosynthetic processGO:0454299.0TLR2, TNF, IL6, IL1B
43positive regulation of interleukin-6 productionGO:0327559.0IL1B, IL6, TNF, TLR2
44apoptotic processGO:0069159.0TLR2, TNF, IL1B, CD14
45positive regulation of NF-kappaB transcription factor activityGO:0510929.0TLR2, TNF, IL6, IL1B
46negative regulation of cell proliferationGO:0082858.9TLR2, TNF, IL6, IL1B
47response to hypoxiaGO:0016668.8SLC6A4, P2RX3, TNF, TLR2
48response to mechanical stimulusGO:0096128.7NGF, TNF, P2RX3, IL6
49positive regulation of transcription from RNA polymerase II promoterGO:0459448.6TLR2, TNF, IL2, IL6, IL1B
50inflammatory responseGO:0069547.6CD14, TLR2, NGF, TNF, SCN9A, IL6

Molecular functions related to Burning Mouth Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lipoteichoic acid bindingGO:0708919.6CD14, TLR2
2growth factor activityGO:0080839.3IL6, IL2, NGF
3cytokine activityGO:0051258.4IL1B, IL6, IL2, TNF

Products for genes affiliated with Burning Mouth Syndrome

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Sources for Burning Mouth Syndrome

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet