MCID: BRN009
MIFTS: 52

Burning Mouth Syndrome

Categories: Rare diseases, Neuronal diseases, Oral diseases

Aliases & Classifications for Burning Mouth Syndrome

MalaCards integrated aliases for Burning Mouth Syndrome:

Name: Burning Mouth Syndrome 12 50 56 42 14 69
Stomatodynia 50 56 69
Stomatopyrosis 12 56
Orodynia 12 56
Bms 50 56
Burning Mouth Disorder 50
Oral Dysesthesia 56

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:4331
MeSH 42 D002054
NCIt 47 C62545
SNOMED-CT 64 111349000 399165002
Orphanet 56 ORPHA353253
UMLS via Orphanet 70 C0006430 C2930806
ICD10 via Orphanet 34 K14.6
UMLS 69 C0006430

Summaries for Burning Mouth Syndrome

NIH Rare Diseases : 50 burning mouth syndrome is characterized by long-lasting burning sensations of the mouth. the pain may affect the tongue, gums, lips, palate, throat, or the entire mouth. burning mouth syndrome may be primary or secondary. experts believe that the primary form may be caused by damage to the nerves that control pain and taste. the secondary form is caused by an underlying medical condition. in many cases, the underlying cause in unknown. treatment depends on the symptoms present and aims to control them. last updated: 3/28/2016

MalaCards based summary : Burning Mouth Syndrome, also known as stomatodynia, is related to burning mouth syndrome type 3 and glossodynia, and has symptoms including oral manifestations and burning tongue. An important gene associated with Burning Mouth Syndrome is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Akt Signaling and PAK Pathway. The drugs Clonazepam and Anticonvulsants have been mentioned in the context of this disorder. Affiliated tissues include tongue, testes and brain, and related phenotypes are behavior/neurological and cardiovascular system

Wikipedia : 72 Burning mouth syndrome (BMS) is a burning sensation in the mouth with no underlying dental or medical... more...

Related Diseases for Burning Mouth Syndrome

Diseases in the Burning Mouth Syndrome family:

Burning Mouth Syndrome Type 3

Diseases related to Burning Mouth Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 264)
id Related Disease Score Top Affiliating Genes
1 burning mouth syndrome type 3 12.1
2 glossodynia 11.3
3 glossitis 11.1
4 burns 11.0
5 solitary plasmacytoma of chest wall 10.7 IL2 IL6
6 labyrinthine bilateral reactive loss 10.6 IL2 IL6
7 orthostatic proteinuria 10.6 IL2 IL6
8 oculomotor nerve paralysis 10.5 IL1B IL6
9 common peroneal nerve lesion 10.5 IL1B IL6
10 hypermobility of coccyx 10.5 NGF TRPV1
11 marasmus 10.5 NGF TRPV1
12 infancy electroclinical syndrome 10.5 IL1B IL6
13 congenital nonspherocytic hemolytic anemia 10.5 IL1B IL6
14 brain compression 10.5 NGF TRPV1
15 scoliosis, arachnodactyly, and blindness 10.5 IL1B IL6
16 subglottis neoplasm 10.5 IL1B IL6
17 bullous retinoschisis 10.5 IL1B IL6
18 carbuncle 10.5 IL1B IL6
19 philophthalmiasis 10.5 IL1B IL6
20 syphilitic encephalitis 10.4 IL1B IL6
21 smarca4-deficient sarcoma of thorax 10.4 IL6 TNF
22 aortic arch interruption 10.4 IL6 TNF
23 malignant renovascular hypertension 10.4 NGF TAC1
24 cutaneous leishmaniasis 10.4 IL6 TNF
25 cryptogenic organizing pneumonia 10.4 TAC1 TRPV1
26 scirrhous adenocarcinoma 10.4 IL2 TNF
27 toxoplasmosis 10.4 IL6 TNF
28 dyslexia 5 10.4 IL6 TNF
29 pseudoainhum 10.4 NGF TAC1
30 epstein-barr virus hepatitis 10.4 IL6 TNF
31 anencephaly and spina bifida x-linked 10.4 IL6 TNF
32 antigen-peptide-transporter 2 deficiency 10.4 IL6 TNF
33 papilledema 10.4 IL6 TNF
34 ethmoid sinus adenocarcinoma 10.4 IL6 TNF
35 autoimmune polyglandular syndrome type 3 10.4 IL2 TNF
36 potato nose 10.4 IL6 TNF
37 cholera 10.4 IL1B IL6
38 pasteurellosis 10.4 IL6 TNF
39 hemangioma of orbit 10.4 IL2 TNF
40 vogt-koyanagi-harada disease 10.4 IL6 TNF
41 cicatricial lagophthalmos 10.4 IL6 TNF
42 whistling face syndrome, recessive form 10.4 IL1B IL2
43 plantar wart 10.4 IL2 TNF
44 tricho onychic dysplasia 10.4 IL6 TNF
45 phlyctenulosis 10.4 IL6 TNF
46 islet cell tumor 10.4 IL6 TNF
47 influenza 10.4 IL1B NGF
48 bone benign neoplasm 10.3 TAC1 TRPV1
49 hypogonadotropism 10.3 IL6 TNF
50 parametritis 10.3 IL2 TNF

Graphical network of the top 20 diseases related to Burning Mouth Syndrome:



Diseases related to Burning Mouth Syndrome

Symptoms & Phenotypes for Burning Mouth Syndrome

UMLS symptoms related to Burning Mouth Syndrome:


oral manifestations, burning tongue

MGI Mouse Phenotypes related to Burning Mouth Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.8 IL2 IL6 NGF SCN9A TAC1 TNF
2 cardiovascular system MP:0005385 9.7 IL1B IL2 IL6 NGF TAC1 TNF
3 integument MP:0010771 9.5 IL1B IL6 NGF SCN9A TAC1 TNF
4 neoplasm MP:0002006 9.02 IL2 IL6 TNF TRPV1 IL1B

Drugs & Therapeutics for Burning Mouth Syndrome

Drugs for Burning Mouth Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 68)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clonazepam Approved, Illicit Phase 4,Early Phase 1 1622-61-3 2802
2 Anticonvulsants Phase 4,Early Phase 1
3 GABA Agents Phase 4,Early Phase 1
4 GABA Modulators Phase 4,Early Phase 1
5 Neurotransmitter Agents Phase 4,Phase 2,Early Phase 1
6
Acetylcholine Approved Phase 2 51-84-3 187
7
Bupivacaine Approved, Investigational Phase 2 2180-92-9, 38396-39-3 2474
8 abobotulinumtoxinA Phase 2
9 Botulinum Toxins Phase 2
10 Botulinum Toxins, Type A Phase 2
11 Cholinergic Agents Phase 2
12 Neuromuscular Agents Phase 2
13 onabotulinumtoxinA Phase 2
14 Peripheral Nervous System Agents Phase 2
15 Pharmaceutical Solutions Phase 2
16 Angiogenesis Inhibitors Phase 2
17 Angiogenesis Modulating Agents Phase 2
18 Anti-Bacterial Agents Phase 2
19 Anti-Infective Agents Phase 2
20 Immunosuppressive Agents Phase 2
21 Central Nervous System Depressants Phase 2
22 Anesthetics Phase 2
23 Anesthetics, Local Phase 2
24
Glycerol Approved, Investigational 56-81-5 753
25
Tolnaftate Approved, Vet_approved Early Phase 1 2398-96-1 5510
26
Capsaicin Approved 404-86-4 1548943
27
Iron Approved 7439-89-6 23925
28
Lidocaine Approved, Vet_approved 137-58-6 3676
29
Lorazepam Approved 846-49-1 3958
30
Nalbuphine Approved 20594-83-6 5360630 5311304
31
Naloxone Approved, Vet_approved 465-65-6 5284596
32
Melatonin Approved, Nutraceutical, Vet_approved 73-31-4 896
33
Folic Acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
34
leucovorin Approved, Nutraceutical 58-05-9 143 6006
35
Glutamic Acid Approved, Nutraceutical 56-86-0 33032
36
Butyric Acid Experimental 107-92-6 264
37
gamma-Aminobutyric acid Investigational 56-12-2 119
38 Carboxymethylcellulose Sodium
39 Antioxidants
40 Protective Agents
41 Antipruritics
42 Dermatologic Agents
43 Micronutrients
44 Thioctic Acid
45 Trace Elements
46 Vitamin B Complex
47 Vitamins
48 Antibodies
49 Autoantibodies
50 Hematinics

Interventional clinical trials:

(show all 20)

id Name Status NCT ID Phase Drugs
1 Effectiveness of Mucolox® and Clonazepam in Treatment of Burning Mouth Syndrome Not yet recruiting NCT02690844 Phase 4 Clonazepam mixed with Mucolox®;Mucolox® alone;Clonazepam
2 Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders Completed NCT00374673 Phase 3
3 Botulinum Toxin in Burning Mouth Syndrome Completed NCT02964728 Phase 2 Botulinum Neurotoxin Type A
4 Thalidomide to Treat Oral Lesions in HIV-Infected Patients Completed NCT00001524 Phase 2 Thalidomide
5 Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain Terminated NCT01584947 Phase 2 Bupivacaine;Placebo
6 Effect of Gluten Free Diet in Patients With Burning Mouth Syndrome Unknown status NCT01867151
7 Burning Mouth Disorder (BMD) - A Neuropathic Pain Disorder Unknown status NCT00504387
8 The Role of Xerostomia in Burning Mouth Syndrome: Case - Control Study Completed NCT01754740 Uréia;Placebo
9 A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome Completed NCT00862576
10 Efficacy of Melatonin in Burning Mouth Syndrome (BMS) Completed NCT02580734
11 Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN) Completed NCT02686359
12 Acupuncture Versus Clonazepam in Burning Mouth Syndrome Completed NCT02382029 Early Phase 1 Clonazepam
13 Neurogenic Mechanisms in Burning Mouth Syndrome Completed NCT00875537
14 Study Evaluating the Laser Diode Effect Burning Mouth Syndrome Completed NCT02757612
15 Alpha Lipoic Acid for Burning Mouth Completed NCT00387543
16 Pain and Sensory Changes Assessment in HIV+ Patients Completed NCT00422695
17 Evaluation and Treatment of Oral Soft Tissue Diseases Completed NCT00001601
18 HLA-DRB1 and HLA-DQB1 Genotyping for Autoantibody-positive and -Negative Patients With Atrophic Glossitis or Burning Mouth Syndrome Recruiting NCT01931293
19 Assessment of Peripheral GABA Receptors for Local Pain Relief Recruiting NCT02928328 GABA oral solution;Intramuscular GABA;Pain modulation
20 Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain Terminated NCT00716807 nalbuphine plus naloxone;nalbuphine plus placebo;nalbuphine plus naloxone;nalbuphine plus placebo

Search NIH Clinical Center for Burning Mouth Syndrome

Cochrane evidence based reviews: burning mouth syndrome

Genetic Tests for Burning Mouth Syndrome

Anatomical Context for Burning Mouth Syndrome

MalaCards organs/tissues related to Burning Mouth Syndrome:

39
Tongue, Testes, Brain, Thyroid, Skin, Colon, Cortex

Publications for Burning Mouth Syndrome

Articles related to Burning Mouth Syndrome:

(show top 50) (show all 466)
id Title Authors Year
1
A case-control evaluation of fungiform papillae density in burning mouth syndrome. ( 28833164 )
2017
2
Burning mouth syndrome. ( 28569120 )
2017
3
Altered structural connectivity of pain-related brain network in burning mouth syndrome-investigation by graph analysis of probabilistic tractography. ( 28361345 )
2017
4
Topical Clonazepam Solution for the Management of Burning Mouth Syndrome: A Retrospective Study. ( 28738111 )
2017
5
Burning mouth syndrome: results of screening tests for vitamin and mineral deficiencies, thyroid hormone, and glucose levels-experience at Mayo Clinic over a decade. ( 28436021 )
2017
6
The Significance of Brain Transcranial Sonography in Burning Mouth Syndrome: a Pilot Study. ( 28740270 )
2017
7
Effects of low-level laser therapy on burning mouth syndrome. ( 27893167 )
2017
8
Analgesic effect of topical oral capsaicin gel in burning mouth syndrome. ( 28007005 )
2017
9
RF-Burning Mouth Syndrome: New Treatments. ( 27702434 )
2017
10
Profiling intraoral neuropathic disturbances following lingual nerve injury and in burning mouth syndrome. ( 28330489 )
2017
11
A diagnostic and therapeutic approach to primary burning mouth syndrome. ( 28916026 )
2017
12
Pain-relieving effects of clonazepam and amitriptyline in burning mouth syndrome: a retrospective study. ( 28473243 )
2017
13
Chronic Orofacial Pain: Burning Mouth Syndrome and Other Neuropathic Disorders. ( 28638895 )
2017
14
Comparison of Salivary Cortisol and I+-amylase Levels and Psychological Profiles in Patients with Burning Mouth Syndrome. ( 28112423 )
2017
15
A A9burningA9 therapy for burning mouth syndrome: preliminary results with the administration of topical capsaicin. ( 28691458 )
2017
16
Is it SjAPgren's syndrome or burning mouth syndrome? Distinct pathoses with similar oral symptoms. ( 28283095 )
2017
17
Burning mouth syndrome: a systematic review of treatments. ( 28247977 )
2017
18
Botulinum Toxin for Burning Mouth Syndrome. ( 28395302 )
2017
19
Little evidence to support or refute interventions for the management of burning mouth syndrome. ( 28642559 )
2017
20
Online Information on the Treatment of Burning Mouth Syndrome: Quality and Readability. ( 28437511 )
2017
21
Refractory burning mouth syndrome: clinical and paraclinical evaluation, comorbiities, treatment and outcome. ( 28357703 )
2017
22
Potential protein biomarkers for burning mouth syndrome discovered by quantitative proteomics. ( 28326926 )
2017
23
Neuropathic Pain in Patients with Burning Mouth Syndrome Evaluated Using painDETECT. ( 28057813 )
2017
24
Relationships between oral MUC1 expression and salivary hormones in burning mouth syndrome. ( 28199919 )
2017
25
Interventions for treating burning mouth syndrome. ( 27855478 )
2016
26
Opiorphin levels in fluids of burning mouth syndrome patients: a case-control study. ( 27834029 )
2016
27
Low-dose aripiprazole for refractory burning mouth syndrome. ( 27279742 )
2016
28
Burning mouth syndrome associated with varicella zoster virus. ( 27382016 )
2016
29
Burning mouth syndrome. ( 26745781 )
2016
30
A systematic review of randomized trials for the treatment of burning mouth syndrome. ( 27302545 )
2016
31
Impact of reassurance on pain perception in patients with primary burning mouth syndrome. ( 27101802 )
2016
32
Taste function assessed by electrogustometry in burning mouth syndrome: a case control study. ( 28029722 )
2016
33
Co-occurrence of Pain Symptoms and Somatosensory Sensitivity in Burning Mouth Syndrome: A Systematic Review. ( 27657531 )
2016
34
An overview of burning mouth syndrome. ( 26709657 )
2016
35
The Detection of Small-Fiber Neuropathies in Burning Mouth Syndrome and Iatrogenic Lingual Nerve Injuries: Use of Quantitative Sensory Testing. ( 27128472 )
2016
36
Burning Mouth Syndrome and "Burning Mouth Syndrome". ( 27209717 )
2016
37
Combined Acupuncture and Auriculotherapy in Burning Mouth Syndrome Treatment: A Preliminary Single-Arm Clinical Trial. ( 27585312 )
2016
38
Low-Dose Aripiprazole Augmentation in Amitriptyline-Resistant Burning Mouth Syndrome: Results from Two Cases. ( 27558854 )
2016
39
Opiorphin in burning mouth syndrome patients: a case-control study. ( 28013436 )
2016
40
Efficacy of Low Level Laser Therapy in the Treatment of Burning Mouth Syndrome: A Systematic Review. ( 27919663 )
2016
41
Burning Mouth Syndrome. ( 26962284 )
2016
42
Pain Part 8: Burning Mouth Syndrome. ( 27439272 )
2016
43
Role of psychological factors in burning mouth syndrome: A systematic review and meta-analysis. ( 27121358 )
2016
44
The relationship between the clinical features of idiopathic burning mouth syndrome and self-perceived quality of life. ( 28025430 )
2016
45
Management of burning mouth syndrome. ( 27134471 )
2016
46
Burning Mouth Syndrome: A Review of the Etiopathologic Factors and Management. ( 27207008 )
2016
47
Comparative Analysis of Psychological, Hormonal, and Genetic Factors Between Burning Mouth Syndrome and Secondary Oral Burning. ( 26849950 )
2016
48
Burning mouth syndrome: Clinical description, pathophysiological approach, and a new therapeutic option. ( 26778734 )
2016
49
Grey matter changes of the pain matrix in patients with burning mouth syndrome. ( 26741696 )
2016
50
Primary Burning Mouth Syndrome: A Questionnaire Study of Neuropathic and Psychological Components. ( 26691521 )
2016

Variations for Burning Mouth Syndrome

Expression for Burning Mouth Syndrome

Search GEO for disease gene expression data for Burning Mouth Syndrome.

Pathways for Burning Mouth Syndrome

Pathways related to Burning Mouth Syndrome according to GeneCards Suite gene sharing:

(show top 50) (show all 52)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.24 IL1B IL2 IL6 NGF TNF
2
Show member pathways
13.13 IL1B IL2 IL6 NGF TNF
3
Show member pathways
12.74 IL1B IL2 IL6 TNF
4
Show member pathways
12.72 IL1B IL2 IL6 TNF
5
Show member pathways
12.66 IL1B IL2 IL6 TNF
6 12.53 IL2 IL6 NGF TNF
7
Show member pathways
12.47 IL1B IL2 IL6 TNF
8
Show member pathways
12.45 IL1B IL2 IL6 TNF
9
Show member pathways
12.45 IL1B IL2 IL6 NGF TNF
10 12.3 IL2 IL6 TNF
11
Show member pathways
12.3 IL1B IL2 IL6 TNF
12
Show member pathways
12.21 IL1B IL6 TNF
13
Show member pathways
12.16 IL1B IL6 TNF
14 12.12 IL1B IL6 TNF
15
Show member pathways
12.08 IL1B IL6 TNF
16
Show member pathways
11.91 IL1B IL2 IL6 TNF
17 11.9 IL2 IL6 TNF
18 11.88 IL1B IL6 TNF
19 11.86 IL1B IL6 TNF
20 11.81 IL1B IL6 TNF
21 11.8 IL1B IL6 TNF
22 11.79 IL1B IL6 TNF
23 11.75 IL1B IL6 TNF
24 11.75 IL1B IL2 IL6 TNF
25 11.69 IL1B IL2 TNF
26 11.66 IL1B IL6 TNF
27
Show member pathways
11.65 IL1B IL2 IL6 TNF
28 11.57 IL1B IL6 TNF
29 11.57 IL1B IL6 NGF TAC1 TNF
30 11.5 IL1B IL6 TNF
31 11.46 IL2 IL6 TNF
32 11.44 IL1B IL2 IL6 TNF
33 11.43 IL1B IL6 TNF
34 11.42 IL1B IL6 TNF
35 11.4 IL1B IL2 TNF
36 11.37 IL1B IL6 TNF
37
Show member pathways
11.31 IL2 TNF
38
Show member pathways
11.26 IL1B IL2 IL6 TNF
39 11.25 IL1B IL6
40 11.23 IL1B IL6 TNF
41 11.21 NGF TNF
42 11.21 NGF TRPV1
43 11.21 IL1B IL6 TNF
44 11.16 IL1B IL6 TNF
45 11.12 IL1B IL6 TNF
46 11.06 IL1B IL2 IL6 TNF
47 11.04 IL1B TNF
48 11.03 IL6 TNF
49 10.96 IL6 TNF
50 10.87 IL1B TNF

GO Terms for Burning Mouth Syndrome

Cellular components related to Burning Mouth Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.13 IL6 TNF TRPV1
2 extracellular region GO:0005576 9.1 IL1B IL2 IL6 NGF TAC1 TNF

Biological processes related to Burning Mouth Syndrome according to GeneCards Suite gene sharing:

(show all 43)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.93 IL1B IL2 IL6 TNF
2 MAPK cascade GO:0000165 9.87 IL1B IL2 TNF
3 positive regulation of gene expression GO:0010628 9.86 IL1B IL6 NGF TNF
4 positive regulation of apoptotic process GO:0043065 9.84 IL6 NGF TNF TRPV1
5 response to lipopolysaccharide GO:0032496 9.83 IL1B IL6 TAC1
6 positive regulation of protein phosphorylation GO:0001934 9.82 IL1B IL2 TNF
7 cell-cell signaling GO:0007267 9.81 IL1B IL2 NGF TAC1
8 positive regulation of cytosolic calcium ion concentration GO:0007204 9.8 IL2 TAC1 TRPV1
9 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.79 IL1B IL6 TNF
10 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.75 IL1B IL6 TNF
11 cellular response to nerve growth factor stimulus GO:1990090 9.69 TAC1 TRPV1
12 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.68 IL1B TNF
13 protein kinase B signaling GO:0043491 9.68 IL1B TNF
14 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.68 IL1B IL2
15 lipopolysaccharide-mediated signaling pathway GO:0031663 9.68 IL1B TNF
16 extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 9.67 NGF TNF
17 positive regulation of phagocytosis GO:0050766 9.67 IL1B TNF
18 cellular response to cytokine stimulus GO:0071345 9.67 IL6 TRPV1
19 positive regulation of interleukin-8 production GO:0032757 9.66 IL1B TNF
20 positive regulation of NF-kappaB import into nucleus GO:0042346 9.65 IL1B TNF
21 response to pain GO:0048265 9.65 TAC1 TRPV1
22 negative regulation of lipid catabolic process GO:0050995 9.64 IL1B TNF
23 positive regulation of chemokine production GO:0032722 9.64 IL6 TNF
24 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.63 IL1B TNF
25 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.61 IL1B TNF
26 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.61 IL1B TNF
27 positive regulation of T cell proliferation GO:0042102 9.61 IL1B IL2 IL6
28 positive regulation of acute inflammatory response GO:0002675 9.6 IL6 TAC1
29 behavioral response to pain GO:0048266 9.59 SCN9A TRPV1
30 positive regulation of immunoglobulin secretion GO:0051024 9.58 IL2 IL6
31 positive regulation of chemokine biosynthetic process GO:0045080 9.57 IL1B TNF
32 negative regulation of lipid storage GO:0010888 9.55 IL6 TNF
33 sensory perception of pain GO:0019233 9.54 SCN9A TAC1 TRPV1
34 regulation of establishment of endothelial barrier GO:1903140 9.52 IL1B TNF
35 positive regulation of interleukin-6 production GO:0032755 9.5 IL1B IL6 TNF
36 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.49 IL6 TNF
37 fever generation GO:0001660 9.48 IL1B TRPV1
38 positive regulation of fever generation GO:0031622 9.46 IL1B TNF
39 sequestering of triglyceride GO:0030730 9.4 IL1B TNF
40 positive regulation of interferon-gamma production GO:0032729 9.33 IL1B IL2 TNF
41 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.26 IL1B TNF
42 positive regulation of nitric oxide biosynthetic process GO:0045429 9.26 IL1B IL6 TNF TRPV1
43 inflammatory response GO:0006954 9.1 IL1B IL6 SCN9A TAC1 TNF TRPV1

Molecular functions related to Burning Mouth Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.13 IL2 IL6 NGF
2 cytokine activity GO:0005125 8.92 IL1B IL2 IL6 TNF

Sources for Burning Mouth Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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