MCID: CND004
MIFTS: 57

Candidiasis malady

Categories: Rare diseases, Infectious diseases, Genetic diseases, Immune diseases, Blood diseases, Skin diseases

Aliases & Classifications for Candidiasis

Aliases & Descriptions for Candidiasis:

Name: Candidiasis 12 52 3 42 14 69
Systemic Candidiasis 12 50 69
Invasive Candidiasis 50 3 69
Disseminated Candidiasis 12 52
Systemic Candida Infections 50

Classifications:



External Ids:

Disease Ontology 12 DOID:1508
ICD10 33 B37 B37.9
ICD9CM 35 112 112.9
MeSH 42 D002177
NCIt 47 C26711
UMLS 69 C0006840

Summaries for Candidiasis

NIH Rare Diseases : 50 systemic candidiasis includes a spectrum of yeast infections caused by different species (types) of candida. it is a serious infection that can affect the blood, heart, brain, eyes, bones, or other parts of the body. although there are over 200 species of candida, five different species of candida cause 90% of systemic candidiasis. the most common form of this invasive yeast infection is when candida enters the bloodstream (candidemia). signs of candidemia include fever and chills that do not improve with antibiotics. symptoms of other types of systemic candidiasis depend on the organ or system which is infected. systemic candidiasis is the most common fungal infection among hosptilized people in high-income countries, including the united states. diagnosis can be difficult, especially when the candida is not found in the bloodstream. treatment usually includes consists of oral or intravenous (iv) antifungal medications.  last updated: 12/15/2016

MalaCards based summary : Candidiasis, also known as systemic candidiasis, is related to esophageal candidiasis and hepatitis. An important gene associated with Candidiasis is AIRE (Autoimmune Regulator), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Fluconazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and tongue, and related phenotypes are hematopoietic system and homeostasis/metabolism

Disease Ontology : 12 An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.

CDC : 3 Photomicrograph of the fungus Candida albicans

Wikipedia : 71 Candidiasis is a fungal infection due to any type of Candida (a type of yeast). When it affects the... more...

Related Diseases for Candidiasis

Diseases in the Candidiasis family:

Candidiasis, Familial, 9 Candidiasis, Familial, 6, Autosomal Dominant
Candidiasis, Familial, 8 Candidiasis, Familial, 2, Autosomal Recessive
Candidiasis, Familial, 3 Candidiasis, Familial, 4, Autosomal Recessive
Candidiasis, Familial, 5, Autosomal Recessive Familial Candidiasis

Diseases related to Candidiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 285)
id Related Disease Score Top Affiliating Genes
1 esophageal candidiasis 33.3 IFNG IL10 IL17A
2 hepatitis 29.8 CLEC7A IFNG IL10
3 sclerosing cholangitis 29.2 DEFB4A HTN3 SKAP2
4 oral candidiasis 12.4
5 vulvovaginal candidiasis 12.3
6 chronic mucocutaneous candidiasis 12.3
7 neonatal candidiasis 12.2
8 cutaneous candidiasis 12.1
9 candidiasis, familial, 2, autosomal recessive 12.1
10 candidiasis, familial, 6, autosomal dominant 12.1
11 candidiasis, familial, 8 12.1
12 candidiasis, familial, 4, autosomal recessive 12.1
13 familial candidiasis 12.0
14 candidiasis, familial, 9 12.0
15 candidiasis, familial, 5, autosomal recessive 11.9
16 autoimmune polyendocrine syndrome type 1 11.7
17 candidiasis, familial, 3 11.7
18 autoimmune polyendocrinopathy syndrome , type i, with or without reversible metaphyseal dysplasia 11.6
19 candidal paronychia 11.6
20 immunodeficiency 31c, autosomal dominant 11.5
21 vaginitis 11.2
22 myeloperoxidase deficiency 11.0
23 median rhomboid glossitis 11.0
24 biotinidase deficiency 11.0
25 immunodeficiency 32b, monocyte and dendritic cell deficiency, autosomal recessive 10.8
26 immunodeficiency 42 10.8
27 vulvovaginitis 10.7
28 immunodeficiency 7, tcr-alpha/beta deficient 10.7
29 immunodeficiency with thymoma 10.7
30 severe combined immunodeficiency, x-linked 10.7
31 immunodeficiency 26, with or without neurologic abnormalities 10.7
32 autoimmune polyendocrine syndrome, type ii 10.7
33 esophagitis 10.5
34 kleefstra syndrome 10.3 CARD9 CLEC7A
35 metaphyseal chondrodysplasia, schmid type 10.3 CLEC7A TRAF3IP2
36 waldeyer's ring cancer 10.3 CARD9 CLEC7A DEFB4A
37 congenital hypothyroidism 10.2 CARD9 CLEC7A IL10
38 gonococcal synovitis 10.2 CLEC7A MBL2 STAT1
39 asymptomatic neurosyphilis 10.2 IFNG IL10
40 isolated growth hormone deficiency 10.2 DEFB4A IFNG STAT1
41 lepromatous leprosy 10.2 IFNG IL10 IL17F
42 dieulafoy lesion 10.2 CARD9 IFNG MBL2
43 heart conduction disease 10.1 IFNG IL10 STAT1
44 depressed scar 10.1 IFNG IL10 STAT1
45 nguyen syndrome 10.1 IL10 IL17A
46 malignant renovascular hypertension 10.1 CD79A IFNG
47 indomethacin antenatal infection 10.1 CD79A MBL2
48 oral cavity carcinoma in situ 10.1 IFNG IL10 MBL2
49 bacterial vaginosis 10.1
50 periventricular leukomalacia 10.1 DEFB4A IFNG IL17A

Comorbidity relations with Candidiasis via Phenotypic Disease Network (PDN): (show all 13)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Chronic Kidney Failure
Decubitus Ulcer Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Hydronephrosis Intestinal Obstruction
Paralytic Ileus Protein-Energy Malnutrition
Respiratory Failure

Graphical network of the top 20 diseases related to Candidiasis:



Diseases related to Candidiasis

Symptoms & Phenotypes for Candidiasis

MGI Mouse Phenotypes related to Candidiasis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.17 AIRE APCS CARD9 CD79A CLEC7A IFNG
2 homeostasis/metabolism MP:0005376 10.07 AIRE APCS CARD9 CD79A CLEC7A IFNG
3 immune system MP:0005387 10.06 TRAF3IP2 AIRE APCS CARD9 CD79A CLEC7A
4 digestive/alimentary MP:0005381 9.97 STAT1 TRAF3IP2 AIRE CLEC7A IFNG IL10
5 no phenotypic analysis MP:0003012 9.5 AIRE CD79A IFNG IL10 IL17A IL17RA
6 respiratory system MP:0005388 9.23 AIRE CLEC7A IFNG IL10 IL17A IL17F

Drugs & Therapeutics for Candidiasis

Drugs for Candidiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 198)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluconazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 86386-73-4 3365
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 22916-47-8 4189
3
Anidulafungin Approved, Investigational Phase 4,Phase 3,Phase 2 166663-25-8 166548
4
Amphotericin B Approved, Investigational Phase 4,Phase 3,Phase 2 1397-89-3 14956 5280965
5
Micafungin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 235114-32-6 3081921 477468
6
Clindamycin Approved, Vet_approved Phase 4,Phase 3,Early Phase 1 18323-44-9 29029
7
Clotrimazole Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 23593-75-1 2812
8
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
9
Caspofungin Approved Phase 4,Phase 3,Phase 2 179463-17-3, 162808-62-0 468682 2826718
10
Voriconazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137234-62-9 71616
11 Dequalinium Approved Phase 4 6707-58-0
12
Terconazole Approved Phase 4,Early Phase 1 67915-31-5 441383
13
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
14
Nystatin Approved, Vet_approved Phase 4,Phase 3,Phase 2 1400-61-9 11953884
15
Metronidazole Approved Phase 4,Phase 3,Phase 2,Early Phase 1 443-48-1 4173
16
Itraconazole Approved, Investigational Phase 4,Phase 3,Phase 1 84625-61-6 55283
17
Ephedrine Approved Phase 4 299-42-3 9294
18
Pseudoephedrine Approved Phase 4 90-82-4 7028
19
Ciclopirox Approved, Investigational Phase 4 29342-05-0 2749
20
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
21
Mycophenolic acid Approved Phase 4 24280-93-1 446541
22
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
23
Butyric Acid Experimental Phase 4 107-92-6 264
24 Antifungal Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
25 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
26 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
27 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
28 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
29 Hormones Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
30 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
31 Steroid Synthesis Inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
32 Echinocandins Phase 4,Phase 2,Phase 3,Phase 1
33 Adrenergic Agents Phase 4,Phase 3,Phase 2
34 Adrenergic Agonists Phase 4,Phase 3,Phase 2
35 Adrenergic beta-2 Receptor Agonists Phase 4,Phase 3,Phase 2
36 Adrenergic beta-Agonists Phase 4,Phase 3,Phase 2
37 Anti-Allergic Agents Phase 4,Phase 3,Phase 2
38 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
39 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
40 Autonomic Agents Phase 4,Phase 3,Phase 2
41 Bronchodilator Agents Phase 4,Phase 3,Phase 2
42 Dermatologic Agents Phase 4,Phase 3,Phase 2
43
Fluticasone Phase 4,Phase 3,Phase 2 90566-53-3, 80474-14-2 62924 22833648
44 Fluticasone Propionate, Salmeterol Xinafoate Drug Combination Phase 4,Phase 3
45 glucocorticoids Phase 4,Phase 3,Phase 2
46 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
47 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
48 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
49
Salmeterol xinafoate Phase 4,Phase 3 94749-08-3 56801
50 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 2,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 280)
id Name Status NCT ID Phase
1 Clinical Significance of Smear or Culture Positive for Candida Spp. From Sputum Three Times a Week Unknown status NCT00537888 Phase 4
2 A Pilot Study for the Use of Biomarkers and Early Treatment of Invasive Candidiasis in Intensive Care Unit (ICU) Patients Unknown status NCT01734525 Phase 4
3 Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 Mcg BID Unknown status NCT00235053 Phase 4
4 Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis Completed NCT02248506 Phase 4
5 Single Dose Versus Two Weeks Course of Fluconazole in the Treatment of Oropharyngeal Candidiasis in HIV Infected Individuals in Tanzania Completed NCT00553137 Phase 4
6 An Efficacy and Safety Study of Miconazole and Hydrocortisone Cream in the Treatment of Vulvar Candidiasis Completed NCT01769339 Phase 4
7 Randomized Study of Caspofungin Prophylaxis Followed by Pre-emptive Therapy for Invasive Candidiasis in the Intensive Care Unit (ICU) Completed NCT00520234 Phase 4
8 Study Will Evaluate The Safety And Efficacy Of Anidulafungin In Patients With Candidemia Or Invasive Candidiasis Completed NCT00496197 Phase 4
9 Comparative Efficacy Study of 10 mg Dequalinium Chloride (Fluomizin) in the Treatment of Vulvovaginal Candidiasis Completed NCT02242695 Phase 4
10 Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasis Completed NCT02180828 Phase 4
11 This Is An Open-Label, Non-Comparative Study Designed To Evaluate A Short Course Of IV Anidulafungin, Followed Optionally By Oral Voriconazole, For The Treatment Of Candidemia And Invasive Candidiasis Completed NCT00548262 Phase 4
12 A Study to Compare the Use of Fluconazole as Continuous Therapy Versus Periodic Therapy in HIV-Positive Patients With Recurrent Thrush Completed NCT00000951 Phase 4
13 CRITIC - Treatment of Candidemia and Invasive Candidiasis Completed NCT00670657 Phase 4
14 Terconazole Vaginal Suppository vs Fluconazole for the Treatment of Severe Vulvovaginal Candidiasis Completed NCT02180100 Phase 4
15 Fluconazole Prophylaxis of Thrush in AIDS Completed NCT00001542 Phase 4
16 Optimized Radiological Diagnosis of Hepatic Candidiasis During the Treatment of Acute Leukemias Completed NCT01207843 Phase 4
17 Optimal Dosage of Caspofungin in Critically Ill Patients Completed NCT01994096 Phase 4
18 Acetato de Caspofungin (Cancidas®) in the Treatment of Fungal Infection Completed NCT00388167 Phase 4
19 Prospective Two-Year Study to Assess Miconazole Nitrate Resistance in Neonates and Infants Completed NCT00702507 Phase 4
20 Comparison of Two Treatments to Prevent Invasive Fungal Infections in Patients Who Have Received Liver Transplants Completed NCT00001107 Phase 4
21 Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina Completed NCT00194324 Phase 4
22 Effectiveness of Hygiene Solutions on Denture Biofilm Completed NCT02407834 Phase 4
23 A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections Completed NCT00647907 Phase 4
24 Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients Completed NCT01495039 Phase 4
25 Anidulafungin Pharmacokinetics Given as a Single Intravenous Dose to Obese Patients (ADOPT) Completed NCT02021123 Phase 4
26 Lactoserum (Dermacyd Femina®) and Prevention of Recurrence of Bacterial Vaginosis Completed NCT00556179 Phase 4
27 Pharmacokinetics of Micafungin During Continuous Venovenous Hemofiltration Completed NCT02651038 Phase 4
28 Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections Completed NCT01697826 Phase 4
29 Comparison of Candida Eradication and Serum Cidal Activity of Echinocandins Completed NCT00839540 Phase 4
30 A Study To Assess The Anidulafungin And Voriconazole Concentration In Lung Following Intravenous Administration In Healthy Subjects Completed NCT00940017 Phase 4
31 Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections Recruiting NCT02860845 Phase 4
32 Pharmacokinetics of Micafungin in Patients of Intensive Care Units Recruiting NCT02164890 Phase 4
33 Micafungin Pharmacokinetics in Obese Patients Recruiting NCT03102658 Phase 4
34 Risk Of Severe Hepatic Injury In Patients With Invasive Candidiasis Treated With Echinocandins Terminated NCT01213823 Phase 4
35 A Study to Evaluate the Efficacy and Safety of Micafungin Against Invasive Candidiasis or Candidemia Terminated NCT01982071 Phase 4
36 Post Marketing Study to Evaluate the Safety and Efficacy of Micafungin Against Fungal Infections Caused by Candida Spp or Aspergillus Spp Terminated NCT02646800 Phase 4
37 Safety Study of Ciclopirox Olamine Cream for Dermatomycoses in Children Terminated NCT01646580 Phase 4
38 Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patients Terminated NCT01282879 Phase 4
39 Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients Withdrawn NCT00304772 Phase 4
40 RCT of Postoperative Infections Following Caesarean Section Infections Following Caesarean Section Withdrawn NCT02009098 Phase 4
41 Fluconazole Versus Micafungin in Neonates With Candidiasis Unknown status NCT02145832 Phase 2, Phase 3
42 Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis Unknown status NCT00889356 Phase 3
43 Dysbiosis in Localized Provoked Vulvodynia (LPV) Unknown status NCT02393911 Phase 3
44 Efficacy of Interferon-gamma in Combination With Anidulafungin for the Treatment of Candidemia Unknown status NCT01270490 Phase 3
45 Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight Completed NCT00734539 Phase 3
46 A Comparison of Gentian Violet (GV) Mouth Washes, Nystatin, and Ketoconazole Tabs in Treating Oropharyngeal Candidiasis Completed NCT00128323 Phase 3
47 Comparative Trial of Micafungin Versus Fluconazole for Treating Esophageal Candidiasis Completed NCT00666185 Phase 3
48 Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis Completed NCT00665639 Phase 3
49 Diabetes Mellitus and Vulvovaginal Candidiasis Completed NCT00353561 Phase 3
50 The Study Of Fluconazole For Vulvovaginal Candidiasis Completed NCT01806623 Phase 3

Search NIH Clinical Center for Candidiasis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: candidiasis

Genetic Tests for Candidiasis

Anatomical Context for Candidiasis

MalaCards organs/tissues related to Candidiasis:

39
Brain, Heart, Tongue, Lung, Bone, Skin, Eye

Publications for Candidiasis

Articles related to Candidiasis:

(show top 50) (show all 1820)
id Title Authors Year
1
A Novel Heterozygous Mutation in the STAT1 SH2 Domain Causes Chronic Mucocutaneous Candidiasis, Atypically Diverse Infections, Autoimmunity, and Impaired Cytokine Regulation. ( 28348565 )
2017
2
Pharmacokinetic study of anidulafungin in ICU patients with intra-abdominal candidiasis. ( 28088767 )
2017
3
Comparison of two long-term gestagen regimens in the management of recurrent vulvovaginal candidiasis: A pilot study. ( 28066940 )
2017
4
Elevated nitric oxide in recurrent vulvovaginal candidiasis - association to clinical findings. ( 28052314 )
2017
5
Loss of immune control in HIV-infected patients: how does mucosal candidiasis occur? ( 27922753 )
2017
6
Oropharyngeal Candidiasis: Fungal Invasion and Epithelial Cell Responses. ( 28081240 )
2017
7
Early Onset Invasive Candidiasis in Extremely Low Birth Weight Infants: Perinatal Acquisition Predicts Poor Outcome. ( 28077516 )
2017
8
Chronic Mucocutaneous Candidiasis. ( 28065688 )
2017
9
New and recurrent STAT1 mutations in seven Chinese patients with chronic mucocutaneous candidiasis. ( 27808400 )
2017
10
Chronic mucocutaneous candidiasis associated with an SH2 domain gain-of-function mutation that enhances STAT1 phosphorylation. ( 26948078 )
2016
11
A tale of two yeasts: Saccharomyces cerevisiae as a therapeutic against candidiasis. ( 27580424 )
2016
12
ALS1 and ALS3 gene expression and biofilm formation in Candida albicans isolated from vulvovaginal candidiasis. ( 27376044 )
2016
13
Invasive Esophageal Candidiasis with Chronic Mediastinal Abscess and Fatal Pneumomediastinum. ( 27389822 )
2016
14
Contribution of Candida biomarkers and DNA detection for the diagnosis of invasive candidiasis in ICU patients with severe abdominal conditions. ( 27181045 )
2016
15
Oral candidiasis following steroid therapy for oral lichen planus. ( 26599999 )
2016
16
Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia. ( 26901377 )
2016
17
Problematic dichotomisation of risk for ICU-acquired invasive candidiasis: results using a risk predictive model to categorise three levels of risk from a multicentre prospective cohort of Australian ICU patients. ( 27601224 )
2016
18
Vulvovaginal Candidiasis in Pregnant Women and its Importance for Candida Colonization of Newborns. ( 27552787 )
2016
19
Th2 and Th9 responses in patients with chronic mucocutaneous candidiasis and hyper-IgE syndrome. ( 27474157 )
2016
20
Treatment options for chronic mucocutaneous candidiasis. ( 27161991 )
2016
21
Letter to the editor-chronic disseminated candidiasis. ( 27987095 )
2016
22
Antifungal activity of the piroctone olamine in experimental intra-abdominal candidiasis. ( 27119072 )
2016
23
Adjuvant antifungal therapy using tissue tolerable plasma on oral mucosa and removable dentures in oral candidiasis patients: a randomised double-blinded split-mouth pilot study. ( 26932256 )
2016
24
Elimination of oral candidiasis may increase stimulated whole salivary flow rate. ( 27497081 )
2016
25
Safety, Efficacy, and Exposure-Response of Voriconazole in Pediatric Patients with Invasive Aspergillosis, Invasive Candidiasis, or Esophageal Candidiasis. ( 27636722 )
2016
26
Chronic mucocutaneous candidiasis disease associated with inborn errors of IL-17 immunity. ( 28090315 )
2016
27
Corrigendum: Dual-species transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions. ( 27991566 )
2016
28
Activation of murine invariant NKT cells promotes susceptibility to candidiasis by IL-10-induced modulation of phagocyte antifungal activity. ( 27151377 )
2016
29
Syngonanthus nitens Bong. (Rhul.)-Loaded Nanostructured System for Vulvovaginal Candidiasis Treatment. ( 27556451 )
2016
30
Isolated pulmonary candidiasis in a patient with diabetes mellitus: A rare case report. ( 27656615 )
2016
31
Esophageal candidiasis in HIV positive and HIV negative patients in a general hospital. ( 27728363 )
2016
32
Diagnostic Methods for Detection of Blood-Borne Candidiasis. ( 26519076 )
2016
33
Prevention of Oral Candidiasis After Free Flap Surgery: Role of 3% Sodium Bicarbonate Saline in Oral Care. ( 27669373 )
2016
34
Oral Pathology Quiz #90. Case Number 2. Candidiasis. ( 27159941 )
2016
35
Esophageal Stricture Secondary to Candidiasis in a Child with Glycogen Storage Disease 1b. ( 27066451 )
2016
36
Health-related quality of life as measured with the Short-Form 36 (SF-36) questionnaire in patients with recurrent vulvovaginal candidiasis. ( 27129474 )
2016
37
Candidal carriage predicts candidiasis during topical immunosuppressive therapy: a preliminary retrospective cohort study. ( 27567434 )
2016
38
Microsatellite analysis of genotype distribution patterns of Candida albicans vulvovaginal candidiasis in Nanjing, China and its association with pregnancy, age and clinical presentation. ( 26861467 )
2016
39
Clinical and immunological data of nine patients with chronic mucocutaneous candidiasis disease. ( 26981552 )
2016
40
Chronic mucocutaneous candidiasis: characterization of a family with STAT-1 gain-of-function and development of an ex-vivo assay for Th17 deficiency of diagnostic utility. ( 26621323 )
2016
41
Progresses in vaginal microflora physiology and implications for bacterial vaginosis and candidiasis. ( 27215488 )
2016
42
Concurrent Fowlpox and Candidiasis Diseases in Backyard Chickens with Unusual Pox Lesions in the Bursa of Fabricius. ( 27610735 )
2016
43
The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1. ( 26604104 )
2016
44
Intrauterine Candida albicans Infection Causes Systemic Fetal Candidiasis With Progressive Cardiac Dysfunction in a Sheep Model of Early Pregnancy. ( 27217375 )
2016
45
Chronic mucocutaneous candidiasis presenting as Candida endophthalmitis. ( 27085277 )
2016
46
Epigastric Distress Caused by Esophageal Candidiasis in 2 Patients Who Received Sorafenib Plus Radiotherapy for Hepatocellular Carcinoma: Case Report. ( 26986168 )
2016
47
Ruxolitinib Induces Interleukin 17 and Ameliorates Chronic Mucocutaneous Candidiasis Caused by STAT1 Gain-of-Function Mutation. ( 26787170 )
2016
48
Treatment of Oral Candidiasis Using PhotodithazineAr- Mediated Photodynamic Therapy In Vivo. ( 27253525 )
2016
49
Chronic vulvovaginal candidiasis in patients using a levonorgestrel-containing intrauterine device. ( 27957732 )
2016
50
Impact of a multifaceted educational intervention including serious games to improve the management of invasive candidiasis in critically ill patients. ( 27645566 )
2016

Variations for Candidiasis

Expression for Candidiasis

Search GEO for disease gene expression data for Candidiasis.

Pathways for Candidiasis

Pathways related to Candidiasis according to GeneCards Suite gene sharing:

(show all 17)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.81 CARD9 CD79A CLEC7A DEFB4A HSP90AA1 HTN3
2
Show member pathways
13.21 HSP90AA1 IFNG IL10 IL17A IL17F IL17RA
3
Show member pathways
12.71 HSP90AA1 IFNG IL10 IL17A STAT1
4
Show member pathways
12.44 IFNG IL10 IL17A IL17F STAT1
5
Show member pathways
12.42 HSP90AA1 IFNG IL10 IL17A IL17F STAT1
6 12.29 CARD9 CD79A IFNG IL10 IL17A STAT1
7 12.08 CARD9 CLEC7A IFNG IL10 STAT1
8
Show member pathways
11.99 IFNG IL10 IL17A STAT1
9
Show member pathways
11.79 IFNG IL10 IL17A STAT1
10 11.71 HSP90AA1 IL10 IL17A IL17F STAT1
11 11.65 HSP90AA1 IFNG STAT1
12 11.63 IFNG IL10 IL17A
13 11.59 IFNG IL10 IL17RA
14
Show member pathways
11.56 IFNG IL17A IL17F IL17RA STAT1
15
Show member pathways
11.56 DEFB4A HSP90AA1 IFNG IL17A IL17F IL17RA
16 11.53 IFNG IL10 STAT1
17
Show member pathways
11.32 IL17A IL17F IL17RA IL17RC TRAF3IP2

GO Terms for Candidiasis

Cellular components related to Candidiasis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.32 APCS DEFB4A HSP90AA1 HTN3 IFNG IL10

Biological processes related to Candidiasis according to GeneCards Suite gene sharing:

(show all 18)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.96 AIRE DEFB4A IFNG IL10 IL17A
2 defense response to bacterium GO:0042742 9.8 DEFB4A HTN3 IFNG IL10 MBL2
3 defense response to Gram-positive bacterium GO:0050830 9.72 CARD9 DEFB4A MBL2
4 humoral immune response GO:0006959 9.7 AIRE IFNG TRAF3IP2
5 chaperone-mediated protein complex assembly GO:0051131 9.58 APCS HSP90AA1
6 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.57 IFNG STAT1
7 positive regulation of MHC class II biosynthetic process GO:0045348 9.54 IFNG IL10
8 positive regulation of interleukin-6 secretion GO:2000778 9.54 IL17A IL17F IL17RC
9 negative regulation of viral process GO:0048525 9.51 APCS MBL2
10 defense response to protozoan GO:0042832 9.5 CLEC7A IFNG IL10
11 granulocyte chemotaxis GO:0071621 9.49 IL17RA IL17RC
12 regulation of interleukin-6 biosynthetic process GO:0045408 9.48 CARD9 IL17F
13 fibroblast activation GO:0072537 9.46 IL17A IL17RA
14 defense response to fungus GO:0050832 9.46 HTN3 IL17A IL17RA IL17RC
15 regulation of interleukin-2 biosynthetic process GO:0045076 9.43 CARD9 IL17F
16 negative regulation of growth of symbiont in host GO:0044130 9.43 IFNG IL10 MBL2
17 positive regulation of interleukin-23 production GO:0032747 9.13 IFNG IL17A IL17RA
18 positive regulation of cytokine production involved in inflammatory response GO:1900017 8.92 IL17A IL17F IL17RA IL17RC

Molecular functions related to Candidiasis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 IFNG IL10 IL17A IL17F
2 interleukin-17 receptor activity GO:0030368 8.62 IL17RA IL17RC

Sources for Candidiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
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