MCID: CNN002
MIFTS: 35

Cannabis Abuse malady

Summaries for Cannabis Abuse

About this section
Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Substance abuse, also known as drug abuse, is a patterned use of a substance (drug) in which the user... more...

MalaCards: Cannabis Abuse, also known as marijuana abuse, is related to bipolar disorder and cannabis dependence. An important gene associated with Cannabis Abuse is NGF (nerve growth factor (beta polypeptide)), and among its related pathways are p75(NTR)-mediated signaling and Development MAG-dependent inhibition of neurite outgrowth. The compounds cerebrolysin and ana 12 have been mentioned in the context of this disorder. Affiliated tissues include testes, brain and thyroid.

Disease Ontology:8 A substance abuse that involves the recurring use of cannabis despite negative consequences.

Aliases & Classifications for Cannabis Abuse

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH
See all sources

Aliases & Descriptions:

cannabis abuse 8 10 44 60
marijuana abuse 8 44 60


External Ids:

Disease Ontology8 DOID:9505
ICD9CM27 305.2
SNOMED-CT56 37344009, 268769003
MeSH34 D002189

Related Diseases for Cannabis Abuse

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Cannabis Abuse:



Diseases related to cannabis abuse

Clinical Features for Cannabis Abuse

About this section

Drugs & Therapeutics for Cannabis Abuse

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Cannabis Abuse

Drug clinical trials:

Search ClinicalTrials for Cannabis Abuse

Search NIH Clinical Center for Cannabis Abuse

Search CenterWatch for Cannabis Abuse

Genetic Tests for Cannabis Abuse

About this section

Anatomical Context for Cannabis Abuse

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Cannabis Abuse:

32
Testes, Brain, Thyroid

Animal Models for Cannabis Abuse or affiliated genes

About this section

Publications for Cannabis Abuse

About this section
Sources:
50PubMed
See all sources

Articles related to Cannabis Abuse:

(show top 50)    (show all 84)
idTitleAuthorsYear
1
Cannabis abuse in adolescence and the risk of psychosis: A brief review of the preclinical evidence. (23916409)
2013
2
Monitoring of chronic Cannabis abuse: an LC-MS/MS method for hair analysis. (23305934)
2013
3
Adolescent ischemic stroke associated with anabolic steroid and cannabis abuse. (23382306)
2013
4
A validation of the Cannabis Abuse Screening Test (CAST) using a latent class analysis of the DSM-IV among adolescents. (23519957)
2013
5
Cannabis abuse and brain morphology in schizophrenia: a review of the available evidence. (22907121)
2013
6
Psychometric Properties of the Cannabis Abuse Screening Test in Hungarian Samples of Adolescents and Young Adults. (24217457)
2013
7
Contributions of ethnicity to differential item functioning of cannabis abuse and dependence symptoms. (23384380)
2013
8
Chronic cannabis abuse, delta-9-tetrahydrocannabinol and thyroid function. (22821384)
2013
9
WITHDRAWN: Psychotherapeutic interventions for cannabis abuse and/or dependence in outpatient settings. (23780682)
2013
10
Alcohol and cannabis abuse/dependence symptoms and life satisfaction in young adulthood. (21733007)
2012
11
Validation of the Cannabis Abuse Screening Test in a sample of cannabis inpatients. (22472963)
2012
12
Cannabis abuse and vulnerability to psychosis: targeting preventive services. (22239586)
2012
13
Neurological soft signs in patients with psychosis and cannabis abuse: a systematic review and meta-analysis of paradox. (22716154)
2012
14
The validity of DSM-IV cannabis abuse and dependence criteria in adolescents and the value of additional cannabis use indicators. (21205060)
2011
15
Psychometric properties of the Cannabis Abuse Screening Test (CAST) in a French sample of adolescents. (20869178)
2011
16
Psychometric modeling of cannabis initiation and use and the symptoms of cannabis abuse, dependence and withdrawal in a sample of male and female twins. (21507586)
2011
17
Increased cortical inhibition deficits in first-episode schizophrenia with comorbid cannabis abuse. (19997844)
2010
18
Functional MRI evidence for inefficient attentional control in adolescent chronic cannabis abuse. (20600341)
2010
19
Cannabis abuse and severity of psychotic and affective disorders in Israeli psychiatric inpatients. (19932824)
2010
20
Influence of the serotonin transporter gene polymorphism, cannabis and childhood sexual abuse on phenotype of bipolar disorder: a preliminary study. (20434316)
2010
21
From child maltreatment to adolescent cannabis abuse and dependence: a developmental cascade model. (20883588)
2010
22
Cannabinoid hyperemesis syndrome: clinical diagnosis of an underrecognised manifestation of chronic cannabis abuse. (19291829)
2009
23
The reliability of self-reported cannabis abuse, dependence and withdrawal symptoms: multisite study of differences between general population and treatment groups. (19004561)
2009
24
Design paper: The CapOpus trial: a randomized, parallel-group, observer-blinded clinical trial of specialized addiction treatment versus treatment as usual for young patients with cannabis abuse and psychosis. (18620563)
2008
25
Item response theory analysis of DSM-IV cannabis abuse and dependence criteria in adolescents. (18176333)
2008
26
Cannabis abuse is associated with decision-making impairment among first-episode patients with schizophrenia-spectrum psychosis. (18005495)
2008
27
The effects of cannabis abuse on the symptoms of schizophrenia: patient perspectives. (18666905)
2008
28
Measured environmental contributions to cannabis abuse/dependence in an offspring of twins design. (18583065)
2008
29
Cannabis abuse and risk for psychosis in a prodromal sample. (17383738)
2007
30
Cannabis abuse in patients with schizophrenia: pattern and effects on symptomatology. (17374302)
2007
31
Nicotinic alpha 7 receptors as a new target for treatment of cannabis abuse. (17522306)
2007
32
Lifetime positive symptoms in patients with schizophrenia and cannabis abuse are partially explained by co-morbid addiction. (16806837)
2006
33
Self-change: A pathway to cannabis abuse resolution. (15967588)
2006
34
Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. (17205118)
2006
35
Psychotherapeutic interventions for cannabis abuse and/or dependence in outpatient settings. (16856093)
2006
36
Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals. (16290108)
2005
37
Cannabis abuse is not a risk factor for treatment outcome in methadone maintenance treatment: a 1-year prospective study in an Israeli clinic. (14731193)
2004
38
Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse. (15479672)
2004
39
A response to 'Cannabis abuse and anaesthesia', Mills P M and Penfold N, Anaesthesia 2003; 58: 1125. (15096263)
2004
40
Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. (15260137)
2004
41
Cannabis abuse and oral health care: review and suggestions for management. (14596260)
2003
42
Psychiatric morbidity of cannabis abuse. (21206852)
2003
43
Carbamazepine as an adjunct in the treatment of schizophrenia-like psychosis related to cannabis abuse. (10221641)
1999
44
The relationship between cannabis use and DSM-IV cannabis abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. (10689658)
1998
45
A clinical sign for persistent harmful cannabis abuse?: a pilot study. (8756056)
1996
46
Cannabis abuse and the course of recent-onset schizophrenic disorders. (8161287)
1994
47
Psychosis and cannabis abuse in The Gambia. A case-control study. (8306122)
1993
48
Adjunctive imipramine for dysphoric schizophrenic patients with past histories of cannabis abuse. (1641497)
1992
49
Confirmation of cannabis abuse by the determination of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in urine with high-performance liquid chromatography and electrochemical detection. (3033002)
1987
50
Psychosis after cannabis abuse. (6423193)
1984

Genetic Variations for Cannabis Abuse

About this section

Expression for genes affiliated with Cannabis Abuse

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Cannabis Abuse

Search GEO for disease gene expression data for Cannabis Abuse.

Pathways for genes affiliated with Cannabis Abuse

About this section
Sources:
37NCBI BioSystems Database, 12EMD Millipore
See all sources

Pathways related to Cannabis Abuse according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5NGF, BDNF
29.5NGF, BDNF
39.5NGF, BDNF

Compounds for genes affiliated with Cannabis Abuse

About this section
Sources:
44Novoseek, 59Tocris Bioscience, 11DrugBank, 49PharmGKB, 28IUPHAR, 24HMDB
See all sources

Compounds related to Cannabis Abuse according to GeneCards/GeneDecks:

(show all 22)
idCompoundScoreTop Affiliating Genes
1cerebrolysin449.8NGF, BDNF
2ana 12599.8BDNF, NGF
3tlqp 21599.8BDNF, NGF
4bdnf (human)599.8BDNF, NGF
5gnf 5837599.8BDNF, NGF
67,8-dihydroxyflavone44 5910.8BDNF, NGF
7oseltamivir44 1110.8NGF, BDNF
8rasagiline44 1110.8BDNF, NGF
9hcec449.8NGF, BDNF
10selegiline44 1110.8NGF, BDNF
11methadone44 49 1111.7BDNF, NGF
12k252a449.7BDNF, NGF
13desipramine44 49 1111.7NGF, BDNF
14fluoxetine49 44 28 1112.6NGF, BDNF
15mecamylamine28 44 1111.6CHRNA3, BDNF
166-hydroxydopamine449.6BDNF, NGF
17mptp449.6NGF, BDNF
18capsaicin44 2810.5NGF, BDNF
19levodopa44 1110.5NGF, BDNF
20dbc-amp449.4BDNF, NGF
21anisomycin44 1110.2NGF, BDNF
22acetylcholine44 49 28 11 2413.1NGF, CHRNA3, BDNF

GO Terms for genes affiliated with Cannabis Abuse

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Cannabis Abuse according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of neuron apoptotic processGO:0435249.5NGF, BDNF
2regulation of excitatory postsynaptic membrane potentialGO:0600799.2CHRNA3, BDNF
3positive regulation of neuron differentiationGO:0456669.2NGF, BDNF

Products for genes affiliated with Cannabis Abuse

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cannabis Abuse

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet