MCID: CNN002
MIFTS: 33

Cannabis Abuse malady

Summaries for Cannabis Abuse

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Wikipedia:64 Substance abuse, also known as drug abuse, is a patterned use of a substance (drug) in which the user... more...

MalaCards: Cannabis Abuse, also known as marijuana abuse, is related to bipolar disorder and cannabis dependence. An important gene associated with Cannabis Abuse is NGF (nerve growth factor (beta polypeptide)), and among its related pathways are p75(NTR)-mediated signaling and Development MAG-dependent inhibition of neurite outgrowth. The compounds cerebrolysin and ana 12 have been mentioned in the context of this disorder. Affiliated tissues include brain and thyroid.

Disease Ontology:8 A substance abuse that involves the recurring use of cannabis despite negative consequences.

Aliases & Classifications for Cannabis Abuse

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 27ICD9CM, 35MeSH
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Aliases & Descriptions:

cannabis abuse 8 10 45 61
marijuana abuse 8 45 61


External Ids:

Disease Ontology8 DOID:9505
ICD9CM27 305.2
SNOMED-CT57 37344009, 268769003
MeSH35 D002189

Related Diseases for Cannabis Abuse

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Cannabis Abuse:



Diseases related to cannabis abuse

Clinical Features for Cannabis Abuse

Drugs & Therapeutics for Cannabis Abuse

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Cannabis Abuse

Drug clinical trials:

Search ClinicalTrials for Cannabis Abuse

Search NIH Clinical Center for Cannabis Abuse

Search CenterWatch for Cannabis Abuse

Genetic Tests for Cannabis Abuse

Anatomical Context for Cannabis Abuse

Sources:
33MalaCards
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MalaCards organs/tissues related to Cannabis Abuse:

33
Brain, Thyroid

Animal Models for Cannabis Abuse or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Cannabis Abuse

Sources:
51PubMed
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Articles related to Cannabis Abuse:

(show top 50)    (show all 84)
idTitleAuthorsYear
1
Adolescent ischemic stroke associated with anabolic steroid and cannabis abuse. (23382306)
2013
2
Pathways to Psychosis in Cannabis Abuse. (23491968)
2013
3
Cannabis abuse and brain morphology in schizophrenia: a review of the available evidence. (22907121)
2013
4
Psychometric Properties of the Cannabis Abuse Screening Test in Hungarian Samples of Adolescents and Young Adults. (24217457)
2013
5
Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders. (24028906)
2013
6
WITHDRAWN: Psychotherapeutic interventions for cannabis abuse and/or dependence in outpatient settings. (23780682)
2013
7
Alcohol and cannabis abuse/dependence symptoms and life satisfaction in young adulthood. (21733007)
2012
8
Validation of the Cannabis Abuse Screening Test in a sample of cannabis inpatients. (22472963)
2012
9
Cannabis abuse and vulnerability to psychosis: targeting preventive services. (22239586)
2012
10
Neurological soft signs in patients with psychosis and cannabis abuse: a systematic review and meta-analysis of paradox. (22716154)
2012
11
The validity of DSM-IV cannabis abuse and dependence criteria in adolescents and the value of additional cannabis use indicators. (21205060)
2011
12
Psychometric modeling of cannabis initiation and use and the symptoms of cannabis abuse, dependence and withdrawal in a sample of male and female twins. (21507586)
2011
13
Increased cortical inhibition deficits in first-episode schizophrenia with comorbid cannabis abuse. (19997844)
2010
14
Functional MRI evidence for inefficient attentional control in adolescent chronic cannabis abuse. (20600341)
2010
15
Design paper: The CapOpus trial: a randomized, parallel-group, observer-blinded clinical trial of specialized addiction treatment versus treatment as usual for young patients with cannabis abuse and psychosis. (18620563)
2008
16
Cyclic vomiting and compulsive bathing with chronic cannabis abuse. (18456571)
2008
17
Item response theory analysis of DSM-IV cannabis abuse and dependence criteria in adolescents. (18176333)
2008
18
The association between cannabis abuse and dependence and childhood physical and sexual abuse: evidence from an offspring of twins design. (18482422)
2008
19
Are diagnostic orphans at risk of developing cannabis abuse or dependence? Four-year follow-up of young adult cannabis users not meeting diagnostic criteria. (17716830)
2008
20
The effects of cannabis abuse on the symptoms of schizophrenia: patient perspectives. (18666905)
2008
21
Measured environmental contributions to cannabis abuse/dependence in an offspring of twins design. (18583065)
2008
22
Cannabis abuse and risk for psychosis in a prodromal sample. (17383738)
2007
23
Cannabis abuse in patients with schizophrenia: pattern and effects on symptomatology. (17374302)
2007
24
Nicotinic alpha 7 receptors as a new target for treatment of cannabis abuse. (17522306)
2007
25
Lifetime positive symptoms in patients with schizophrenia and cannabis abuse are partially explained by co-morbid addiction. (16806837)
2006
26
Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. (17205118)
2006
27
Adequate antipsychotic treatment normalizes serum nerve growth factor concentrations in schizophrenia with and without cannabis or additional substance abuse. (16540246)
2006
28
The stability and impact of environmental factors on substance use and problems after adolescent outpatient treatment for cannabis abuse or dependence. (15783279)
2005
29
Collisions and traffic violations of alcohol, cannabis and cocaine abuse clients before and after treatment. (15203356)
2004
30
Cannabis abuse is not a risk factor for treatment outcome in methadone maintenance treatment: a 1-year prospective study in an Israeli clinic. (14731193)
2004
31
Brain-derived neurotrophic factor serum concentrations are increased in drug-naive schizophrenic patients with chronic cannabis abuse and multiple substance abuse. (15500971)
2004
32
Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse. (15479672)
2004
33
A response to 'Cannabis abuse and anaesthesia', Mills P M and Penfold N, Anaesthesia 2003; 58: 1125. (15096263)
2004
34
Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. (15260137)
2004
35
Cannabis abuse in Iran. (12760467)
2003
36
Cannabis abuse and oral health care: review and suggestions for management. (14596260)
2003
37
Chronic cannabis abuse raises nerve growth factor serum concentrations in drug-naive schizophrenic patients. (14870957)
2003
38
Cannabis abuse as a risk factor for depressive symptoms. (11729021)
2001
39
Cannabis abuse and serious suicide attempts. (10615730)
1999
40
Carbamazepine as an adjunct in the treatment of schizophrenia-like psychosis related to cannabis abuse. (10221641)
1999
41
Quantitative EEG findings associated with chronic stimulant and cannabis abuse and ADHD in an adult male substance use disorder population. (10513323)
1999
42
The relationship between cannabis use and DSM-IV cannabis abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. (10689658)
1998
43
A clinical sign for persistent harmful cannabis abuse?: a pilot study. (8756056)
1996
44
Cannabis abuse and the course of recent-onset schizophrenic disorders. (8161287)
1994
45
Psychosis and cannabis abuse in The Gambia. A case-control study. (8306122)
1993
46
An epidemiological study of cannabis abuse among college students of Varanasi. (8144224)
1993
47
Influence of cannabis abuse on schizophrenic psychopathology. (1543037)
1992
48
Adjunctive imipramine for dysphoric schizophrenic patients with past histories of cannabis abuse. (1641497)
1992
49
Confirmation of cannabis abuse by the determination of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in urine with high-performance liquid chromatography and electrochemical detection. (3033002)
1987
50
Psychotic symptoms due to cannabis abuse; (a survey of newly admitted mental patients). (5438330)
1970

Genetic Variations for Cannabis Abuse

Expression for genes affiliated with Cannabis Abuse

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cannabis Abuse

Search GEO for disease gene expression data for Cannabis Abuse.

Pathways for genes affiliated with Cannabis Abuse

Sources:
38NCBI BioSystems Database, 12EMD Millipore
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Pathways related to Cannabis Abuse according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5NGF, BDNF
29.5NGF, BDNF
39.5NGF, BDNF

Compounds for genes affiliated with Cannabis Abuse

Sources:
45Novoseek, 60Tocris Bioscience, 11DrugBank, 50PharmGKB, 29IUPHAR, 24HMDB
See all sources

Compounds related to Cannabis Abuse according to GeneCards/GeneDecks:

(show all 22)
idCompoundScoreTop Affiliating Genes
1cerebrolysin459.8NGF, BDNF
2ana 12609.8BDNF, NGF
3tlqp 21609.8BDNF, NGF
4bdnf (human)609.8BDNF, NGF
5gnf 5837609.8BDNF, NGF
67,8-dihydroxyflavone45 6010.8BDNF, NGF
7oseltamivir45 1110.8NGF, BDNF
8rasagiline45 1110.8BDNF, NGF
9hcec459.8NGF, BDNF
10selegiline45 1110.8NGF, BDNF
11methadone45 50 1111.7BDNF, NGF
12k252a459.7BDNF, NGF
13desipramine45 50 1111.7NGF, BDNF
14fluoxetine50 45 29 1112.6NGF, BDNF
15mecamylamine29 45 1111.6CHRNA3, BDNF
166-hydroxydopamine459.6BDNF, NGF
17mptp459.6NGF, BDNF
18capsaicin45 2910.5NGF, BDNF
19levodopa45 1110.5NGF, BDNF
20dbc-amp459.4BDNF, NGF
21anisomycin45 1110.2NGF, BDNF
22acetylcholine45 50 29 11 2413.1NGF, CHRNA3, BDNF

GO Terms for genes affiliated with Cannabis Abuse

Sources:
16Gene Ontology
See all sources

Biological processes related to Cannabis Abuse according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of neuron apoptotic processGO:0435249.5NGF, BDNF
2regulation of excitatory postsynaptic membrane potentialGO:0600799.2CHRNA3, BDNF
3positive regulation of neuron differentiationGO:0456669.2NGF, BDNF

Products for genes affiliated with Cannabis Abuse

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cannabis Abuse

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet