MCID: CPP003
MIFTS: 25

Cap Polyposis malady

Gastrointestinal diseases, Cancer diseases, Rare diseases categories

Summaries for Cap Polyposis

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34MalaCards
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MalaCards: Cap Polyposis, also known as inflammatory myoglandular polyps, is related to solitary rectal ulcer syndrome and protein-losing enteropathy. An important gene associated with Cap Polyposis is MUC3A (mucin 3A, cell surface associated). The compounds calcium and methotrexate have been mentioned in the context of this disorder. Affiliated tissues include colon.

Aliases & Classifications for Cap Polyposis

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50Orphanet, 63UMLS, 27ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Gastrointestinal diseases


Characteristics (Orphanet epidemiological data):

50
inflammatory myoglandular polyps:
Inheritance: Sporadic; Prevalence: <1/1000000; Age of onset: Variable


Aliases & Descriptions:

cap polyposis 50
inflammatory myoglandular polyps 50
eroded polypoid hyperplasia 50
cap inflammatory polyposis 50
polypoid prolapsing folds 50
multiple polyps 63


External Ids:

ICD10 via Orphanet27 D12.6

Related Diseases for Cap Polyposis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Cap Polyposis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1solitary rectal ulcer syndrome10.5
2protein-losing enteropathy10.4
3ulcerative colitis10.3
4crohn's disease10.1
5rectal prolapse10.1
6breast cancer10.0ALB, MUC3A
7cystic fibrosis9.9ALB, MUC3A

Graphical network of diseases related to Cap Polyposis:



Diseases related to cap polyposis

Symptoms for Cap Polyposis

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Drugs & Therapeutics for Cap Polyposis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Cap Polyposis

Search NIH Clinical Center for Cap Polyposis

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Genetic Tests for Cap Polyposis

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Anatomical Context for Cap Polyposis

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34MalaCards
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MalaCards organs/tissues related to Cap Polyposis:

34
Colon

Animal Models for Cap Polyposis or affiliated genes

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Publications for Cap Polyposis

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Sources:
53PubMed
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Articles related to Cap Polyposis:

(show all 36)
idTitleAuthorsYear
1
Inflammatory cap polyposis in a 42-year-old male. (23416507)
2013
2
Nine-year follow-up from onset to spontaneous complete remission of cap polyposis. (23370743)
2013
3
Cap polyposis and colitis cystica profunda: a rare association. (24118052)
2013
4
Cap polyposis: a rare cause of rectal bleeding in children. (23864782)
2013
5
Cap-polyposis-like gastropathy with hypoproteinemia treated with H. pylori eradication. (24088754)
2013
6
Rectal cap polyposis masquerading as ulcerative colitis with pseudopolyposis and presenting as chronic anemia: a case study with review of literature. (23828750)
2013
7
Cap polyposis mistaken for Crohn's disease: case report and review of literature. (22766527)
2013
8
Long-term outcome of cap polyposis, with special reference to the effects of steroid therapy. (22078102)
2012
9
Successful management of cap polyposis with eradication of Helicobacter pylori relapsing 15 years after remission on steroid therapy. (22333383)
2012
10
Cap polyposis with protein-losing enteropathy. (21869875)
2011
11
Unusual colon polyps. Diagnosis: Cap polyposis. (21878333)
2011
12
Can the stomach be a target of cap polyposis? (20405375)
2010
13
Cap polyposis (CP) which relapsed after remission by avoiding straining at defecation, and was cured by Helicobacter pylori eradication therapy. (19952483)
2009
14
Remission of cap polyposis maintained for more than three years after infliximab treatment. (20431770)
2009
15
Hypoalbuminaemia and colonic polyps: a case of protein-losing enteropathy with cap polyposis? (17847696)
2007
16
Rectal prolapse and cap polyposis: the missing link. (15785885)
2005
17
Confined progression of cap polyposis along the anastomotic line, implicating the role of inflammatory responses in the pathogenesis. (16111972)
2005
18
Pedunculated cap polyps preceding the development of cap polyposis: case report. (15729261)
2005
19
Possible relationship between Helicobacter pylori infection and cap polyposis of the colon. (15610079)
2004
20
Successful treatment of cap polyposis with infliximab. (15188181)
2004
21
Cap polyposis: further experience and review. (15164251)
2004
22
Gastrointestinal: cap polyposis. (12753160)
2003
23
Spontaneous resolution of cap polyposis: case report. (12665781)
2003
24
Does metronidazole cure cap polyposis by its antiinflammatory actions instead of by its antibiotic action? A case study. (12141801)
2002
25
Cap polyposis cured by Helicobacter pylori eradication therapy. (12108681)
2002
26
Proximal extension of cap polyposis confirmed by colonoscopy. (11522989)
2001
27
Cap polyposis of the colon and rectum: an analysis of endoscopic findings. (11293761)
2001
28
Asymptomatic cap polyposis from the sigmoid colon to the cecum. (11677493)
2001
29
A case of &quot;cap polyposis&quot;-like lesion associated with ulcerative colitis: is this a case of cap polyposis? (11095366)
2000
30
Features of cap polyposis by magnifying colonoscopy. (11115917)
2000
31
Successful treatment of cap polyposis by avoidance of intraluminal trauma: clues to pathogenesis. (10950064)
2000
32
Abnormal mucus in cap polyposis. (9518233)
1998
33
A case of cap polyposis investigated by scintigraphy with human serum albumin labeled with Tc-99m DTPA. (9712385)
1998
34
Protein-losing enteropathy from cap polyposis. (7491082)
1995
35
Cap polyposis occurring in the postoperative course of pelvic surgery. (7828996)
1994
36
Cap polyposis--an unusual cause of diarrhoea. (8491408)
1993

Variations for Cap Polyposis

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Expression for genes affiliated with Cap Polyposis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cap Polyposis

Search GEO for disease gene expression data for Cap Polyposis.

Pathways for genes affiliated with Cap Polyposis

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Compounds for genes affiliated with Cap Polyposis

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Sources:
46Novoseek, 52PharmGKB, 25HMDB, 12DrugBank, 30IUPHAR
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Compounds related to Cap Polyposis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium46 52 25 1212.1ALB, MUC3A
2methotrexate52 46 1211.0ALB, MUC3A
3cholesterol46 30 25 1211.8ALB, MUC3A

GO Terms for genes affiliated with Cap Polyposis

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Sources:
17Gene Ontology
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Cellular components related to Cap Polyposis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1ALB, MUC3A

Products for genes affiliated with Cap Polyposis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cap Polyposis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet