MCID: CPP003
MIFTS: 34

Cap Polyposis

Categories: Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Cap Polyposis

MalaCards integrated aliases for Cap Polyposis:

Name: Cap Polyposis 55
Inflammatory Myoglandular Polyps 55
Eroded Polypoid Hyperplasia 55
Cap Inflammatory Polyposis 55
Polypoid Prolapsing Folds 55

Characteristics:

Orphanet epidemiological data:

55
cap polyposis
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: Adolescent,Adult,Childhood,Elderly;

Classifications:



Summaries for Cap Polyposis

MalaCards based summary : Cap Polyposis, also known as inflammatory myoglandular polyps, is related to inflammatory bowel disease and cataract 32, multiple types, and has symptoms including colorectal polyposis, constipation and abdominal pain. An important gene associated with Cap Polyposis is ALB (Albumin), and among its related pathways/superpathways are HIV Life Cycle and CLEC7A (Dectin-1) signaling. Affiliated tissues include colon.

Related Diseases for Cap Polyposis

Diseases related to Cap Polyposis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 inflammatory bowel disease 28.8 ALB MUC2 MUC3A
2 cataract 32, multiple types 10.6
3 solitary rectal ulcer syndrome 10.2
4 colitis 10.1
5 mucinous intrahepatic cholangiocarcinoma 10.1 MUC2 MUC5AC
6 bile duct cystadenocarcinoma 10.1 MUC2 MUC5AC
7 clear cell adenoma 10.1 MUC2 MUC5AC
8 protein-losing enteropathy 10.1
9 biliary papillomatosis 10.1 MUC2 MUC5AC
10 colloid carcinoma of the pancreas 10.1 MUC2 MUC5AC
11 superior mesenteric artery syndrome 10.1 MUC2 MUC5AC
12 ovarian mucinous neoplasm 10.1 MUC2 MUC5AC
13 meconium ileus 10.1 MUC2 MUC5AC
14 gastric tubular adenocarcinoma 10.1 MUC2 MUC5AC
15 pancreatic mucinous cystadenoma 10.0 MUC2 MUC5AC
16 hidradenocarcinoma 10.0 MUC2 MUC5AC
17 pseudomyxoma peritonei 10.0 MUC2 MUC5AC
18 cystitis cystica 10.0 MUC2 MUC5AC
19 ulcerative colitis 10.0
20 cholecystitis 10.0 ALB MUC2
21 epstein-barr virus-associated gastric carcinoma 10.0 MUC2 MUC5AC
22 bile duct adenocarcinoma 10.0 MUC2 MUC5AC
23 small intestinal adenocarcinoma 10.0 MUC2 MUC5AC
24 respiratory system disease 10.0 ALB MUC5AC
25 gastrointestinal system cancer 9.9 ALB MUC2
26 colorectal cancer 1 9.9 MUC2 MUC4
27 filamentary keratitis 9.9 MUC4 MUC5AC
28 mucinous tubular and spindle renal cell carcinoma 9.9 MUC2 MUC4
29 limbal stem cell deficiency 9.9 MUC4 MUC5AC
30 biliary tract neoplasm 9.8 MUC2 MUC4
31 barrett esophagus 9.8 MUC2 MUC5AC
32 pelvic organ prolapse 9.8
33 helicobacter pylori infection 9.8
34 crohn's disease 9.8
35 mucositis 9.8
36 polyposis, skin pigmentation, alopecia, and fingernail changes 9.8 ALB MUC2 MUC5AC
37 otitis media 9.8 ALB MUC2 MUC5AC
38 cystadenoma 9.8 MUC2 MUC4
39 dry eye syndrome 9.7 MUC4 MUC5AC
40 bile duct carcinoma 9.7 MUC2 MUC4
41 adenoma 9.6 MUC2 MUC5AC
42 bile duct mucoepidermoid carcinoma 9.5 MUC2 MUC4 MUC5AC
43 chronic ethmoiditis 9.5 MUC2 MUC4 MUC5AC
44 ethmoid sinusitis 9.5 MUC2 MUC4 MUC5AC
45 pancreas adenocarcinoma 9.5 MUC2 MUC4 MUC5AC
46 mucoepidermoid carcinoma 9.5 MUC2 MUC4 MUC5AC
47 intrahepatic cholangiocarcinoma 9.5 MUC2 MUC4 MUC5AC
48 cholangiocarcinoma 9.5 MUC2 MUC4 MUC5AC
49 pancreatic cancer 9.1 MUC2 MUC4 MUC5AC
50 tn polyagglutination syndrome 9.1 MUC2 MUC3A MUC4 MUC5AC

Graphical network of the top 20 diseases related to Cap Polyposis:



Diseases related to Cap Polyposis

Symptoms & Phenotypes for Cap Polyposis

Human phenotypes related to Cap Polyposis:

55 31 (show all 8)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 colorectal polyposis 55 31 obligate (100%) Obligate (100%) HP:0200063
2 constipation 55 31 hallmark (90%) Very frequent (99-80%) HP:0002019
3 abdominal pain 55 31 hallmark (90%) Very frequent (99-80%) HP:0002027
4 hematochezia 55 31 hallmark (90%) Very frequent (99-80%) HP:0002573
5 chronic atrophic gastritis 55 31 hallmark (90%) Very frequent (99-80%) HP:0002582
6 weight loss 55 31 frequent (33%) Frequent (79-30%) HP:0001824
7 abdominal distention 55 31 frequent (33%) Frequent (79-30%) HP:0003270
8 diarrhea 55 Frequent (79-30%)

Drugs & Therapeutics for Cap Polyposis

Search Clinical Trials , NIH Clinical Center for Cap Polyposis

Genetic Tests for Cap Polyposis

Anatomical Context for Cap Polyposis

MalaCards organs/tissues related to Cap Polyposis:

38
Colon

Publications for Cap Polyposis

Articles related to Cap Polyposis:

(show all 43)
# Title Authors Year
1
Cap polyposis refractory to<i>Helicobacter pylori</i>eradication treated with endoscopic submucosal dissection. ( 29085564 )
2017
2
A Case of Cap Polyposis with Epidermal Nevus in an Infant. ( 28378565 )
2017
3
Protein-losing pseudomembranous colitis with cap polyposis-like features. ( 28522919 )
2017
4
Cap Polyposis Masquerading as Inflammatory Bowel Disease in a Child. ( 27437929 )
2016
5
A case of cap polyposis remission by betamethasone enema after antibiotics therapy including Helicobacter pylori eradication. ( 24949613 )
2014
6
Polypectomy to eradicate cap polyposis with protein-losing enteropathy. ( 25287098 )
2014
7
Cap-polyposis-like gastropathy with hypoproteinemia treated with H. pylori eradication. ( 24088754 )
2013
8
Cap polyposis mistaken for Crohn's disease: case report and review of literature. ( 22766527 )
2013
9
Cap polyposis: a rare cause of rectal bleeding in children. ( 23864782 )
2013
10
Nine-year follow-up from onset to spontaneous complete remission of cap polyposis. ( 23370743 )
2013
11
Rectal cap polyposis masquerading as ulcerative colitis with pseudopolyposis and presenting as chronic anemia: a case study with review of literature. ( 23828750 )
2013
12
Cap polyposis and colitis cystica profunda: a rare association. ( 24118052 )
2013
13
Inflammatory cap polyposis in a 42-year-old male. ( 23416507 )
2013
14
Successful management of cap polyposis with eradication of Helicobacter pylori relapsing 15 years after remission on steroid therapy. ( 22333383 )
2012
15
Long-term outcome of cap polyposis, with special reference to the effects of steroid therapy. ( 22078102 )
2012
16
Unusual colon polyps. Diagnosis: Cap polyposis. ( 21878333 )
2011
17
Cap polyposis with protein-losing enteropathy. ( 21869875 )
2011
18
Can the stomach be a target of cap polyposis? ( 20405375 )
2010
19
Remission of cap polyposis maintained for more than three years after infliximab treatment. ( 20431770 )
2009
20
Cap polyposis (CP) which relapsed after remission by avoiding straining at defecation, and was cured by Helicobacter pylori eradication therapy. ( 19952483 )
2009
21
Hypoalbuminaemia and colonic polyps: a case of protein-losing enteropathy with cap polyposis? ( 17847696 )
2007
22
Confined progression of cap polyposis along the anastomotic line, implicating the role of inflammatory responses in the pathogenesis. ( 16111972 )
2005
23
Cap polyposis: an inflammatory disorder or a spectrum of mucosal prolapse syndrome? ( 16099801 )
2005
24
Rectal prolapse and cap polyposis: the missing link. ( 15785885 )
2005
25
Pedunculated cap polyps preceding the development of cap polyposis: case report. ( 15729261 )
2005
26
Cap polyposis: further experience and review. ( 15164251 )
2004
27
Possible relationship between Helicobacter pylori infection and cap polyposis of the colon. ( 15610079 )
2004
28
Successful treatment of cap polyposis with infliximab. ( 15188181 )
2004
29
Gastrointestinal: cap polyposis. ( 12753160 )
2003
30
Spontaneous resolution of cap polyposis: case report. ( 12665781 )
2003
31
Cap polyposis cured by Helicobacter pylori eradication therapy. ( 12108681 )
2002
32
Does metronidazole cure cap polyposis by its antiinflammatory actions instead of by its antibiotic action? A case study. ( 12141801 )
2002
33
Proximal extension of cap polyposis confirmed by colonoscopy. ( 11522989 )
2001
34
Cap polyposis of the colon and rectum: an analysis of endoscopic findings. ( 11293761 )
2001
35
Asymptomatic cap polyposis from the sigmoid colon to the cecum. ( 11677493 )
2001
36
Features of cap polyposis by magnifying colonoscopy. ( 11115917 )
2000
37
A case of "cap polyposis"-like lesion associated with ulcerative colitis: is this a case of cap polyposis? ( 11095366 )
2000
38
Successful treatment of cap polyposis by avoidance of intraluminal trauma: clues to pathogenesis. ( 10950064 )
2000
39
Abnormal mucus in cap polyposis. ( 9518233 )
1998
40
A case of cap polyposis investigated by scintigraphy with human serum albumin labeled with Tc-99m DTPA. ( 9712385 )
1998
41
Protein-losing enteropathy from cap polyposis. ( 7491082 )
1995
42
Cap polyposis occurring in the postoperative course of pelvic surgery. ( 7828996 )
1994
43
Cap polyposis--an unusual cause of diarrhoea. ( 8491408 )
1993

Variations for Cap Polyposis

Expression for Cap Polyposis

Search GEO for disease gene expression data for Cap Polyposis.

Pathways for Cap Polyposis

GO Terms for Cap Polyposis

Cellular components related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.26 ALB MUC3A MUC4 MUC5AC
2 Golgi lumen GO:0005796 8.92 MUC2 MUC3A MUC4 MUC5AC

Biological processes related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 MUC2 MUC3A MUC4 MUC5AC
2 maintenance of gastrointestinal epithelium GO:0030277 9.16 MUC2 MUC4
3 O-glycan processing GO:0016266 8.92 MUC2 MUC3A MUC4 MUC5AC

Molecular functions related to Cap Polyposis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix structural constituent GO:0005201 8.96 MUC3A MUC5AC
2 extracellular matrix constituent, lubricant activity GO:0030197 8.62 MUC3A MUC4

Sources for Cap Polyposis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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