MCID: CPL006
MIFTS: 56

Capillary Hemangioma

Categories: Genetic diseases, Cardiovascular diseases, Skin diseases, Cancer diseases

Aliases & Classifications for Capillary Hemangioma

MalaCards integrated aliases for Capillary Hemangioma:

Name: Capillary Hemangioma 12 14
Strawberry Nevus of Skin 12 69
Infantile Hemangioma 12 36
Cellular Hemangioma of Infancy 12
Congenital Vascular Hamartoma 12
Congenital Vascular Naevus 12
Strawberry Haemangioma 12
Hemangioma, Cavernous 69
Hemangioma, Capillary 41
Hemangioma Capillary 51
Juvenile Hemangioma 12
Strawberry Nevus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2725
ICD10 32 Q82.5
MeSH 41 D018324
NCIt 46 C6645
KEGG 36 H01482
UMLS 69 C0206733

Summaries for Capillary Hemangioma

MalaCards based summary : Capillary Hemangioma, also known as strawberry nevus of skin, is related to pyogenic granuloma and hemangioma, capillary infantile. An important gene associated with Capillary Hemangioma is TEK (TEK Receptor Tyrosine Kinase), and among its related pathways/superpathways are VEGF signaling pathway and ERK Signaling. The drugs Benzocaine and Nadolol have been mentioned in the context of this disorder. Affiliated tissues include skin, testis and spinal cord, and related phenotypes are cardiovascular system and cellular

Wikipedia : 72 A capillary hemangioma (also known as an Infantile hemangioma,Strawberry hemangioma, and Strawberry... more...

Related Diseases for Capillary Hemangioma

Diseases in the Capillary Hemangioma family:

Hemangioma, Capillary Infantile

Diseases related to Capillary Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
# Related Disease Score Top Affiliating Genes
1 pyogenic granuloma 33.3 TEK VEGFA
2 hemangioma, capillary infantile 32.6 FLT4 KDR
3 hemangioma 30.2 FLT4 KDR PECAM1 SLC2A1 TEK VEGFA
4 cavernous hemangioma 30.0 KDR PECAM1
5 renal cell carcinoma, nonpapillary 28.3 FLT1 FLT4 KDR SLC2A1 VEGFA
6 breast capillary hemangioma 12.1
7 angioma, tufted 11.3
8 capillary malformations, congenital 11.2
9 cerebral cavernous malformations 11.0
10 retinitis 10.5
11 intramuscular hemangioma 10.4 SLC2A1 TEK
12 critical limb ischemia 10.3 TEK VEGFA
13 chronic myocardial ischemia 10.3 TEK VEGFA
14 pediatric angiosarcoma 10.3 HBA1 VEGFA
15 immune hydrops fetalis 10.3 HBA1 RASA1
16 renal pelvis carcinoma 10.3 SLC2A1 VEGFA
17 integumentary system benign neoplasm 10.3 HBA1 SLC2A1
18 pulmonary vein stenosis 10.2 KDR PECAM1
19 von hippel-lindau syndrome 10.2
20 hobnail hemangioma 10.2 FLT4 HBA1
21 senile angioma 10.2 HBA1 KDR
22 hemifacial spasm 10.2 FLT4 VEGFA
23 diabetic macular edema 10.2 TEK VEGFA
24 cardiovascular organ benign neoplasm 10.2 HBA1 SLC2A1 TEK
25 benign perivascular tumor 10.2 HBA1 SLC2A1 TEK
26 glomangioma 10.1 HBA1 SLC2A1 TEK
27 juvenile nasopharyngeal angiofibroma 10.1 PECAM1 VEGFA
28 proctitis 10.1 KDR PECAM1
29 kuhnt-junius degeneration 10.1 KDR VEGFA
30 telangiectasis 10.1 RASA1 VEGFA
31 klippel-trenaunay-weber syndrome 10.1 FLT4 RASA1
32 coats disease 10.1 KDR VEGFA
33 leukostasis 10.0 KDR VEGFA
34 retinal detachment 10.0
35 venous malformations, multiple cutaneous and mucosal 10.0 FLT4 RASA1 TEK
36 radiation proctitis 10.0 KDR PECAM1 VEGFA
37 hydrocele 10.0 FLT4 PECAM1 VEGFA
38 limb ischemia 9.9 KDR TEK VEGFA
39 renal clear cell carcinoma 9.9 KDR TEK VEGFA
40 meningioma, familial 9.9
41 cervicitis 9.9
42 central nervous system hemangioma 9.9
43 mediastinitis 9.9
44 endotheliitis 9.9
45 hemangioendothelioma 9.9 FLT4 KDR PECAM1
46 kaposiform hemangioendothelioma 9.9 FLT4 KDR PECAM1
47 angiomatous meningioma 9.9 HBA1 KDR VEGFA
48 lymphangiosarcoma 9.9 FLT4 HBA1 VEGFA
49 microcystic meningioma 9.9 FLT1 VEGFA
50 cancer-associated retinopathy 9.9 FLT1 VEGFA

Graphical network of the top 20 diseases related to Capillary Hemangioma:



Diseases related to Capillary Hemangioma

Symptoms & Phenotypes for Capillary Hemangioma

MGI Mouse Phenotypes related to Capillary Hemangioma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.06 VEGFA PROM1 FLT1 RASA1 FLT4 KDR
2 cellular MP:0005384 9.98 VEGFA PECAM1 PROM1 FLT1 RASA1 SLC2A1
3 growth/size/body region MP:0005378 9.97 VEGFA PROM1 FLT1 RASA1 FLT4 SLC2A1
4 embryo MP:0005380 9.95 VEGFA FLT1 RASA1 FLT4 SLC2A1 KDR
5 mortality/aging MP:0010768 9.92 VEGFA PROM1 FLT1 RASA1 FLT4 SLC2A1
6 muscle MP:0005369 9.8 VEGFA FLT1 RASA1 FLT4 KDR TEK
7 nervous system MP:0003631 9.7 VEGFA TEK PROM1 FLT1 RASA1 SLC2A1
8 no phenotypic analysis MP:0003012 9.43 VEGFA PROM1 RASA1 FLT4 SLC2A1 KDR
9 normal MP:0002873 9.1 VEGFA PROM1 FLT1 FLT4 KDR TEK

Drugs & Therapeutics for Capillary Hemangioma

Drugs for Capillary Hemangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 137)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
2
Nadolol Approved Phase 3,Phase 2 42200-33-9 39147
3
Propranolol Approved, Investigational Phase 3,Phase 2,Phase 1 525-66-6 4946
4
Timolol Approved Phase 3,Phase 2,Phase 1,Early Phase 1 26839-75-8 5478 33624
5
Ephedrine Approved Phase 3 299-42-3 9294
6
Pseudoephedrine Approved Phase 3 90-82-4 7028
7
Atenolol Approved Phase 3 29122-68-7 2249
8
Acebutolol Approved, Investigational Phase 3 37517-30-9 1978
9 tannic acid Approved, Nutraceutical Phase 3
10
Maleic acid Experimental Phase 3,Phase 2,Phase 1 110-16-7 444266
11 Adrenergic Agents Phase 3,Phase 2,Phase 1,Early Phase 1
12 Adrenergic Antagonists Phase 3,Phase 2,Phase 1,Early Phase 1
13 Adrenergic beta-Antagonists Phase 3,Phase 2,Phase 1,Early Phase 1
14 Anti-Arrhythmia Agents Phase 3,Phase 2,Phase 1,Early Phase 1
15 Antihypertensive Agents Phase 3,Phase 2,Phase 1,Early Phase 1
16 Autonomic Agents Phase 3,Phase 2
17 Neurotransmitter Agents Phase 3,Phase 2,Phase 1,Early Phase 1
18 Peripheral Nervous System Agents Phase 3,Phase 2
19 Sympatholytics Phase 3,Phase 2
20 Vasodilator Agents Phase 3,Phase 2,Phase 1
21 Nasal Decongestants Phase 3
22 Ophthalmic Solutions Phase 3
23 Pharmaceutical Solutions Phase 3,Phase 2,Phase 1,Early Phase 1
24 Respiratory System Agents Phase 3
25 Tetrahydrozoline Phase 3
26 Vasoconstrictor Agents Phase 3
27 Adrenergic beta-1 Receptor Antagonists Phase 3
28 Adrenergic Agonists Phase 3
29 Adrenergic alpha-2 Receptor Agonists Phase 3
30 Adrenergic alpha-Agonists Phase 3
31 Brimonidine Tartrate Phase 3 70359-46-5
32
Bosentan Approved, Investigational Phase 2 147536-97-8 104865
33
Imiquimod Approved, Investigational Phase 2 99011-02-6 57469
34
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
35
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
36
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
37
Everolimus Approved Phase 2,Phase 1 159351-69-6 6442177
38
Miconazole Approved, Investigational, Vet_approved Phase 2,Phase 1 22916-47-8 4189
39
Sirolimus Approved, Investigational Phase 2,Phase 1 53123-88-9 46835353 6436030 5284616
40
Ranibizumab Approved Phase 1, Phase 2 347396-82-1 459903
41
Bleomycin Approved, Investigational Phase 2 11056-06-7 5360373
42
Cyclophosphamide Approved, Investigational Phase 1, Phase 2 50-18-0, 6055-19-2 2907
43
Ranitidine Approved Phase 2 66357-59-3, 66357-35-5 3001055
44
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
45 Strawberry Approved, Nutraceutical Phase 2
46 Endothelin Receptor Antagonists Phase 2
47 Adjuvants, Immunologic Phase 2
48 Interferon Inducers Phase 2
49 interferons Phase 2
50 Anti-Inflammatory Agents Phase 2

Interventional clinical trials:

(show top 50) (show all 81)

# Name Status NCT ID Phase Drugs
1 A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain Recruiting NCT03125057 Phase 4 Hemoporfin PDT
2 Postmarketing Safety Study of Hemoporfin in Patients With Port Wine Stain Recruiting NCT03181984 Phase 4 Hemoporfin
3 Nadolol Versus Propranolol in Children With Infantile Hemangiomas Unknown status NCT02505971 Phase 3 Nadolol;Propranolol
4 Treatment of Port Wine Stains in Children With Pulsed Dye Laser and Timolol Gel Unknown status NCT01272609 Phase 3 Timolol + LCP
5 Topical Timolol for Superficial Infantile Hemangioma Unknown status NCT01685398 Phase 3 0.5% timolol maleate eye drop;Normal saline
6 Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy Completed NCT01056341 Phase 2, Phase 3 Propranolol;Placebo
7 Comparative Study to Evaluate the Effectiveness of Atenolol and Propranolol in the Treatment of Infantile Hemangiomas Recruiting NCT03237637 Phase 3 oral propranolol;oral atenolol
8 Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma Recruiting NCT02342275 Phase 3 Propranolol;Atenolol
9 MELABLOCK: A Clinical Trial on the Efficacy and Safety of Propranolol 80 mg in Melanoma Patients Not yet recruiting NCT02962947 Phase 2, Phase 3 Propranolol;Placebo
10 Onreltea (Brimonidine) Gel In Pediatric Patients With Capillary Malformations Not yet recruiting NCT02764411 Phase 3 Brimonidine 0.33% gel
11 Propranolol in Capillary Hemangiomas Terminated NCT00744185 Phase 2, Phase 3 propranolol treatment;placebo treatment
12 Efficacy and Safety of Propranolol Versus Acebutolol on the Proliferative Phase of Infantile Hemangioma Terminated NCT01743885 Phase 3 Acebutolol;Propanolol
13 Study in Infants With Infantile Hemangioma to Compare Propranolol Gel to Placebo Completed NCT01512173 Phase 2 propranolol gel;Placebo
14 Treatment of Resistant Port-wine Stains With Bosentan and Pulsed Dye Laser: a Pilot Study Completed NCT02317679 Phase 2 Bosentan
15 Nadolol for Proliferating Infantile Hemangiomas Completed NCT01010308 Phase 2 Nadolol
16 Topical Timolol Gel for the Treatment of Infantile Hemangiomas Completed NCT02145884 Phase 2 timolol maleate 0.5% gel
17 The Effects of Aldara as an Adjunct to Laser Treatment Completed NCT00979550 Phase 2 Imiquimod (Aldara);non-medicated petroleum cream
18 Comparative Study of the Use of Beta Blocker and Oral Corticosteroid in the Treatment of Infantile Hemangioma Completed NCT01072045 Phase 2 Propranolol;Prednisone
19 Measurement Skin Temperature During Pulsed Laser Exposure Completed NCT00540917 Phase 2
20 A Phase II Study of Imiquimod 5 % Cream for the Treatment of Hemangioma in Infancy Completed NCT00601016 Phase 2 Imiquimod 5% cream
21 Efficacy, Safety and Pharmacokinetics of Topical Timolol in Infants With Infantile Hemangioma (IH) Recruiting NCT02913612 Phase 2 0.25% Timolol Maleate Gel Forming Solution;0.5% Timolol Maleate Gel Forming Solution
22 Topical Timolol for Infantile Hemangioma in Early Proliferative Phase Recruiting NCT02731287 Phase 2 Timolol;Placebo
23 A Phase I/II Trial for Intravitreous Treatment of Severe Ocular Von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab Recruiting NCT02859441 Phase 1, Phase 2 Ranibizumab;E10030
24 Electrosclerotherapy for Capillary Malformations Recruiting NCT02883023 Phase 2 Intralesional bleomycin injection
25 Dose-Finding of Propranolol in Combination With Metronomic Fixed Oral Cyclophosphamide Based on Bivariate Efficacy-tolerability Outcome in Patients With Locally Advanced or Metastatic Angiosarcoma: A Collaborative and Innovative Phase I-II Sequential Tria Not yet recruiting NCT02732678 Phase 1, Phase 2 PROPRANOLOL
26 Corticosteroids With Placebo Versus Corticosteroids With Propranolol Treatment of Infantile Hemangiomas (IH) Terminated NCT01074437 Phase 2 Prednisolone (Corticosteroid);Propranolol;Placebo
27 Clinical Trial of Vincristine vs. Prednisolone for Treatment of Complicated Hemangiomas Terminated NCT00555464 Phase 2 Vincristine;Prednisone
28 Combined Use of Pulsed Dye Laser and Topical Antiangiogenic Agents for Treatment of Port Wine Stain Birthmarks Withdrawn NCT00969397 Phase 1, Phase 2 Topical Antiangiogenic
29 Timolol Option for Ulcerated Hemangiomas (TOUCH Trial) Withdrawn NCT01408056 Phase 2 Timolol 0.5% Gel Forming Solution (GFS);Mupirocin 2% Ointment
30 Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS) Withdrawn NCT01997255 Phase 2 Everolimus
31 A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks. Completed NCT00800722 Phase 1 Rapamycin Treatment of Port Wine Stain
32 Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks: Comparison of 577 nm Versus 595 nm Wavelengths Completed NCT00573729 Phase 1
33 A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks. Completed NCT00830466 Phase 1 Laser and rapamycin versus laser alone
34 Treatment of Vascular Lesions With a Tandem 532/1064 nm Laser Completed NCT00585338 Phase 1
35 Optical Clearing of the Skin in Conjunction With Laser Treatments Completed NCT00580736 Phase 1
36 Combined Bipolar Radiofrequency&Pulsed Dye Laser Treatment Recruiting NCT01775722 Phase 1
37 Novel Treatment for Port Wine Stain Birthmarks Recruiting NCT01924273 Phase 1 Talaporfin sodium
38 Timolol for the Prevention of Proliferation of Infantile Hemangioma (TiPPIH Trial) Terminated NCT01434849 Phase 1 topical 0.5% Timolol maleate;Control (placebo) group
39 Combined Alexandrite and Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks Withdrawn NCT00580944 Phase 1
40 Combined Pulsed Dye Laser and Topical Ranibizumab for Treatment of Port Wine Stain Birthmarks Withdrawn NCT00667472 Phase 1 Ranibizumab
41 Pilot Study on the Use of the Matrix Radiofrequencyfor Treatment of Port Wine Stain Birthmarks Withdrawn NCT01166919 Phase 1
42 The Angioma's Treatment Evaluation With Laser Doppler Imaging (LDI) Unknown status NCT01759082
43 Evaluation and Optimization of the Technical and Clinical Performance of the Lumenis ONE Platform Unknown status NCT00247299
44 Clinical Characteristics of Lip Hemangiomas Unknown status NCT02351245
45 A Prospective Study Comparing the Incidence of Infantile Hemangiomas Following Normal Pregnancies Versus Pregnancies Complicated by Placental Abnormalities Unknown status NCT00490607
46 Assessing the Effects of Air-cooling on Capillary Malformations Unknown status NCT01735734
47 Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High Fluences Completed NCT00540371
48 Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain Birthmarks Completed NCT00585247 Imiquimod
49 Combined Photodynamic and Pulsed Dye Laser Treatment of Port Wine Stains Completed NCT00556946 Combined Photodynamic & Pulsed Dye Laser Treatment
50 Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment Completed NCT01774552

Search NIH Clinical Center for Capillary Hemangioma

Cochrane evidence based reviews: hemangioma, capillary

Genetic Tests for Capillary Hemangioma

Anatomical Context for Capillary Hemangioma

MalaCards organs/tissues related to Capillary Hemangioma:

38
Skin, Testis, Spinal Cord, Lung, Bone, Eye, Retina

Publications for Capillary Hemangioma

Articles related to Capillary Hemangioma:

(show top 50) (show all 438)
# Title Authors Year
1
Venous outlet syndrome caused by capillary hemangioma of the subclavian vein. ( 29444598 )
2018
2
Solitary Retinal Capillary Hemangioma with Nonlipid Exudative Retinal Detachment. ( 29389404 )
2018
3
Long-Term Therapeutic Outcomes of Photodynamic Therapy-Based or Photocoagulation-Based Treatments on Retinal Capillary Hemangioma. ( 29068750 )
2018
4
Combined Oral and Topical Beta Blockers for the Treatment of Early Proliferative Superficial Periocular Infantile Capillary Hemangioma. ( 28991344 )
2018
5
SOLITARY RETINAL CAPILLARY HEMANGIOMA IN A PATIENT WITH BILATERAL CHORIORETINAL COLOBOMA. ( 28358746 )
2017
6
A Rare Cause of Hemoptysis in Childhood: Tracheal Capillary Hemangioma. ( 29404177 )
2017
7
Intradural-extramedullary capillary hemangioma with acute bleeding, case report and literature review. ( 28823662 )
2017
8
In Vivo Microvascular Pattern of Solitary Juxtapapillary Capillary Hemangioma on OCT Angiography. ( 28728187 )
2017
9
Nasal Lobular Capillary Hemangioma as a Complication after an Endoscopic Transsphenoidal Gonadotrophin-Producing Pituitary Adenoma Resection. ( 28326242 )
2017
10
Subcutaneous Lobular Capillary Hemangioma on 68Ga-PSMA PET/CT. ( 28114225 )
2017
11
Lobular capillary hemangioma (pyogenic granuloma) of the oral cavity. ( 28719705 )
2017
12
A case of solitary pulmonary capillary hemangioma indicating true gross appearance. ( 28419636 )
2017
13
Rare cause for hemoptysis in an adolescent: Bronchial capillary hemangioma. ( 28165678 )
2017
14
Spinal epidural capillary hemangioma: A rare case report with a review of literature. ( 28713627 )
2017
15
Prevalence and pattern of lobular capillary hemangioma in Eastern Madhya Pradesh, India: A clinicopathological analysis. ( 28836535 )
2017
16
Solitary pulmonary capillary hemangioma presents as ground glass opacity on computed tomography indicating adenocarcinoma<i>in situ</i>/atypical adenomatous hyperplasia: A case report. ( 29188054 )
2017
17
Capillary Hemangioma of the Tympanic Membrane. ( 28349759 )
2017
18
Localised longitudinal erythronychia caused by subungual capillary hemangioma. ( 28726279 )
2017
19
Conjunctival Capillary Hemangioma. ( 29392104 )
2017
20
A Case of Giant Intradural Extramedullary Capillary Hemangioma. ( 28091424 )
2017
21
Challenging Pitfalls and Mimickers in Diagnosing Anastomosing Capillary Hemangioma of the Kidney: Case Report and Literature Review. ( 28286335 )
2017
22
Capillary Hemangioma of the Tympanic Membrane and External Auditory Canal. ( 28106702 )
2017
23
Capillary Hemangioma of Thoracic Spinal Cord: PET/CT and MR Findings. ( 28195909 )
2017
24
Pediatric Intranasal Lobular Capillary Hemangioma: A Rare Clinical Entity. ( 29215342 )
2017
25
Intradural Extramedullary Capillary Hemangioma In the Upper Thoracic Spine with Simultaneous Extensive Arachnoiditis. ( 28704911 )
2017
26
Capillary Hemangioma of the Tympanic Membrane and External Auditory Canal. ( 28468198 )
2017
27
Congenital capillary hemangioma arising from palpebral conjunctiva of a neonate. ( 29133659 )
2017
28
Unusual Case of Acquired Capillary Hemangioma of the Eyelid in an Adult. ( 29264305 )
2017
29
Rapidly enlarging acquired capillary hemangioma of the eyelid. ( 28400395 )
2017
30
Vulvar Lobular Capillary Hemangioma: A Rare Location for a Frequent Entity. ( 28127485 )
2016
31
Juvenile capillary hemangioma. ( 27057499 )
2016
32
Capillary Hemangioma of the Fallopian Tube. ( 27190899 )
2016
33
Capillary Hemangioma of the Breast-a Rare Type of benign Breast Tumor. ( 26687640 )
2016
34
Capillary hemangioma of the testis. A case report of a rare benign tumor. ( 27104006 )
2016
35
Intradural Extramedullary Capillary Hemangioma in the Upper Cervical Spine: First Report. ( 27185649 )
2016
36
Lobular capillary hemangioma of the tracheobronchial tree: A case report and literature review. ( 27902613 )
2016
37
Intravenous Lobular Capillary Hemangioma in the Subclavian Vein. ( 27772599 )
2016
38
Case report of lumbar intradural capillary hemangioma. ( 27069745 )
2016
39
How to manage testicular capillary haemangioma: Editorial Comment on: W. BiaA8ek, S. Rudzki, L. Wroniecki: Capillary hemangioma of the testis. A case report of a rare benign tumor. ( 27104008 )
2016
40
Intravascular Lobular Capillary Hemangioma in the Corpus Spongiosum. ( 26730699 )
2016
41
Tracheal lobular capillary hemangioma treated with laser photocoagulation. ( 26982046 )
2016
42
Intravitreal bevacizumab and feeder vessel laser treatment for a posteriorly located retinal capillary hemangioma. ( 26815929 )
2016
43
Multiparametric sonographic imaging of a capillary hemangioma of the testis: appearances on gray-scale, color Doppler, contrast-enhanced ultrasound and strain elastography. ( 26941881 )
2016
44
Lobular Capillary Hemangioma Originating From the Posterior Portion of the Inferior Turbinate. ( 27483103 )
2016
45
Capillary hemangioma or pyogenic granuloma. ( 27041829 )
2016
46
Spinal Intradural Extramedulary Capillary Hemangioma Mimicking Meningioma. ( 27799982 )
2016
47
A case of giant fetal intracranial capillary hemangioma cured with propranolol. ( 26824594 )
2016
48
Pleural effusion caused by a capillary hemangioma in the pleural cavity. ( 27087237 )
2016
49
Pediatric intranasal lobular capillary hemangioma: Report of two new cases and review of the literature. ( 27144115 )
2016
50
Gastrointestinal Pyogenic Granuloma (Lobular Capillary Hemangioma): An Underrecognized Entity Causing Iron Deficiency Anemia. ( 27403353 )
2016

Variations for Capillary Hemangioma

Cosmic variations for Capillary Hemangioma:

9 (show all 14)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM580 NRAS soft tissue,skin,haemangioma,capillary c.181C>A p.Q61K 7
2 COSM584 NRAS soft tissue,skin,haemangioma,capillary c.182A>G p.Q61R 7
3 COSM521 KRAS soft tissue,skin,haemangioma,capillary c.35G>A p.G12D 7
4 COSM516 KRAS soft tissue,skin,haemangioma,capillary c.34G>T p.G12C 7
5 COSM529 KRAS soft tissue,skin,haemangioma,capillary c.37G>C p.G13R 7
6 COSM6503576 HRAS soft tissue,skin,haemangioma,capillary c.100C>T p.P34S 7
7 COSM486 HRAS soft tissue,skin,haemangioma,capillary c.37G>C p.G13R 7
8 COSM487 HRAS soft tissue,skin,haemangioma,capillary c.37G>A p.G13S 7
9 COSM6503574 HRAS soft tissue,skin,haemangioma,capillary c.145G>A p.E49K 7
10 COSM6503575 HRAS soft tissue,skin,haemangioma,capillary c.44G>A p.G15D 7
11 COSM499 HRAS soft tissue,skin,haemangioma,capillary c.182A>G p.Q61R 7
12 COSM52975 GNAQ soft tissue,skin,haemangioma,capillary c.548G>A p.R183Q 7
13 COSM449 BRAF soft tissue,skin,haemangioma,capillary c.1391G>A p.G464E 7
14 COSM476 BRAF soft tissue,skin,haemangioma,capillary c.1799T>A p.V600E 7

Expression for Capillary Hemangioma

Search GEO for disease gene expression data for Capillary Hemangioma.

Pathways for Capillary Hemangioma

Pathways related to Capillary Hemangioma according to KEGG:

36
# Name Kegg Source Accession
1 VEGF signaling pathway hsa04370

Pathways related to Capillary Hemangioma according to GeneCards Suite gene sharing:

(show all 38)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.62 FLT1 FLT4 KDR RASA1 TEK VEGFA
2
Show member pathways
13.52 FLT1 FLT4 KDR RASA1 TEK VEGFA
3
Show member pathways
13.1 FLT1 FLT4 KDR SLC2A1 TEK
4
Show member pathways
13.07 FLT1 FLT4 KDR TEK VEGFA
5
Show member pathways
12.8 FLT1 FLT4 KDR TEK
6
Show member pathways
12.76 FLT1 FLT4 KDR TEK VEGFA
7
Show member pathways
12.71 FLT1 FLT4 KDR VEGFA
8 12.57 FLT1 FLT4 KDR RASA1 TEK VEGFA
9
Show member pathways
12.52 FLT1 FLT4 KDR RASA1 TEK VEGFA
10
Show member pathways
12.44 FLT1 FLT4 KDR VEGFA
11
Show member pathways
12.27 FLT1 FLT4 KDR
12
Show member pathways
12.22 KDR RASA1 VEGFA
13
Show member pathways
12.21 FLT1 FLT4 KDR VEGFA
14
Show member pathways
12.17 FLT1 FLT4 KDR VEGFA
15
Show member pathways
12.05 FLT1 KDR VEGFA
16
Show member pathways
12.04 FLT1 FLT4 KDR TEK
17 11.94 FLT1 FLT4 KDR TEK
18 11.92 KDR PECAM1 VEGFA
19 11.9 KDR PROM1 VEGFA
20 11.88 FLT1 KDR VEGFA
21
Show member pathways
11.83 KDR RASA1 VEGFA
22
Show member pathways
11.82 FLT1 KDR VEGFA
23 11.76 FLT1 SLC2A1 TEK VEGFA
24 11.71 FLT1 TEK VEGFA
25
Show member pathways
11.66 FLT1 FLT4 KDR
26 11.62 PROM1 SLC2A1 VEGFA
27
Show member pathways
11.52 FLT1 FLT4 KDR RASA1 VEGFA
28
Show member pathways
11.48 FLT1 FLT4 KDR
29 11.3 FLT1 FLT4 KDR PECAM1 TEK
30
Show member pathways
11.29 KDR VEGFA
31 11.29 FLT1 FLT4 KDR VEGFA
32 11.23 RASA1 TEK
33 11.22 SLC2A1 VEGFA
34 11.15 FLT1 KDR SLC2A1 VEGFA
35 11.05 FLT1 VEGFA
36 10.94 FLT1 KDR TEK VEGFA
37 10.84 FLT1 FLT4 KDR TEK
38
Show member pathways
10.13 FLT1 FLT4 KDR VEGFA

GO Terms for Capillary Hemangioma

Cellular components related to Capillary Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.76 FLT1 FLT4 KDR PECAM1 PROM1 RASA1
2 extracellular region GO:0005576 9.73 FLT1 FLT4 HBA1 KDR TEK VEGFA
3 integral component of plasma membrane GO:0005887 9.43 FLT1 FLT4 KDR PROM1 SLC2A1 TEK
4 membrane raft GO:0045121 8.92 KDR PECAM1 SLC2A1 TEK

Biological processes related to Capillary Hemangioma according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 phosphorylation GO:0016310 9.96 FLT1 FLT4 KDR TEK
2 protein phosphorylation GO:0006468 9.95 FLT1 FLT4 KDR TEK
3 negative regulation of apoptotic process GO:0043066 9.93 FLT4 KDR RASA1 TEK VEGFA
4 positive regulation of cell proliferation GO:0008284 9.92 FLT1 FLT4 KDR VEGFA
5 protein autophosphorylation GO:0046777 9.83 FLT1 FLT4 KDR TEK
6 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.81 FLT4 KDR TEK
7 peptidyl-tyrosine phosphorylation GO:0018108 9.81 FLT1 FLT4 KDR TEK
8 positive regulation of cell migration GO:0030335 9.8 FLT1 KDR VEGFA
9 positive regulation of protein phosphorylation GO:0001934 9.8 FLT4 KDR TEK VEGFA
10 regulation of cell shape GO:0008360 9.79 KDR RASA1 VEGFA
11 positive regulation of angiogenesis GO:0045766 9.78 FLT1 KDR TEK VEGFA
12 angiogenesis GO:0001525 9.77 FLT1 FLT4 KDR TEK VEGFA
13 positive regulation of MAPK cascade GO:0043410 9.76 FLT1 FLT4 KDR
14 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.74 FLT1 KDR TEK
15 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.73 FLT1 FLT4 KDR TEK
16 vasculogenesis GO:0001570 9.72 KDR RASA1 VEGFA
17 positive regulation of blood vessel endothelial cell migration GO:0043536 9.65 KDR VEGFA
18 negative regulation of endothelial cell apoptotic process GO:2000352 9.64 KDR TEK
19 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.64 FLT1 TEK
20 blood vessel morphogenesis GO:0048514 9.63 FLT1 FLT4 RASA1
21 sprouting angiogenesis GO:0002040 9.62 FLT4 TEK
22 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.62 FLT1 FLT4 KDR VEGFA
23 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.61 FLT1 VEGFA
24 cell migration involved in sprouting angiogenesis GO:0002042 9.6 KDR VEGFA
25 positive regulation of positive chemotaxis GO:0050927 9.59 KDR VEGFA
26 positive regulation of protein kinase C signaling GO:0090037 9.58 FLT4 VEGFA
27 positive regulation of focal adhesion assembly GO:0051894 9.58 KDR TEK VEGFA
28 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.56 KDR VEGFA
29 positive regulation of endothelial cell proliferation GO:0001938 9.56 FLT4 KDR TEK VEGFA
30 vascular endothelial growth factor signaling pathway GO:0038084 9.33 FLT1 FLT4 KDR
31 positive regulation of endothelial cell migration GO:0010595 9.26 FLT4 KDR TEK VEGFA
32 cellular response to vascular endothelial growth factor stimulus GO:0035924 8.92 FLT1 FLT4 KDR VEGFA

Molecular functions related to Capillary Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kinase activity GO:0016301 9.71 FLT1 FLT4 KDR TEK
2 protein kinase activity GO:0004672 9.62 FLT1 FLT4 KDR TEK
3 protein tyrosine kinase activity GO:0004713 9.56 FLT1 FLT4 KDR TEK
4 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.46 FLT1 FLT4 KDR TEK
5 vascular endothelial growth factor-activated receptor activity GO:0005021 9.13 FLT1 FLT4 KDR
6 growth factor binding GO:0019838 8.92 FLT1 FLT4 KDR TEK
7 protein binding GO:0005515 10.07 FLT1 FLT4 HBA1 KDR PECAM1 PROM1

Sources for Capillary Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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