MCID: CRC004
MIFTS: 33

Carcinoid Tumor of Lung malady

Respiratory diseases, Cancer diseases categories

Summaries for Carcinoid Tumor of Lung

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32MalaCards
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MalaCards: Carcinoid Tumor of Lung is related to cushing's syndrome and acromegaly. An important gene associated with Carcinoid Tumor of Lung is MEN1 (multiple endocrine neoplasia I), and among its related pathways are Endothelin and Calcitonin-like ligand receptors. The compounds estrogen and acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include lung, and related mouse phenotypes are tumorigenesis and nervous system.

Aliases & Classifications for Carcinoid Tumor of Lung

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46OMIM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Respiratory diseases


Aliases & Descriptions:

carcinoid tumor of lung 46


Related Diseases for Carcinoid Tumor of Lung

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Carcinoid Tumor of Lung via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 123)
idRelated DiseaseScoreTop Affiliating Genes
1cushing's syndrome30.2MEN1, NPY, CALCA
2acromegaly10.0MEN1
3pituitary tumors10.0MEN1
4parathyroid carcinoma10.0MEN1
5uremia10.0MEN1
6hemangioma10.0MEN1
7subependymal giant cell astrocytoma10.0ENO2
8wilms tumor10.0ENO2
9merkel cell carcinoma10.0ENO2
10teratoma10.0ENO2
11vipoma10.0MEN1
12wermer syndrome10.0MEN1
13dementia10.0CST3
14endometriosis10.0MIF
15adrenocortical carcinoma10.0TP53
16gingivitis10.0CST3
17somatostatinoma10.0CALCA
18neuropathy10.0CALCA
19glioblastoma multiforme10.0TP53
20amyotrophic lateral sclerosis10.0CST3
21thyroiditis10.0CALCA
22chondrosarcoma10.0ENO2
23ulcerative colitis10.0TP53
24migraine10.0CALCA
25adrenal adenoma10.0MEN1
26schizophrenia10.0NPY
27giant cell tumor10.0CALCA
28von hippel-lindau disease10.0MEN1, NPY
29ependymoma10.0MEN1, ENO2
30ganglioneuroblastoma10.0ENO2, NPY
31benign meningioma10.0CST3
32status epilepticus10.0ENO2, NPY
33osteosarcoma10.0TP53
34pancreatitis10.0GCG
35pituitary adenoma10.0MIF, MEN1
36hyperinsulinemic hypoglycemia10.0GCG
37meningioma10.0CST3, MEN1
38cluster headache10.0CALCA
39neuroblastoma10.0TP53, ENO2
40rhabdomyosarcoma10.0ENO2, TP53
41leukemia10.0MEN1, TP53
42hyperparathyroidism10.0CALCA, MEN1
43multiple endocrine neoplasia10.0MEN1, CALCA
44astrocytoma10.0TP53, IAPP
45hemorrhage, intracerebral10.0ENO2, CST3
46gastritis10.0TP53, MIF
47malignant mixed mullerian tumor10.0TP53, ENO2
48osteoarthritis10.0NPY, CALCA
49cholestasis10.0GCG
50sarcoma10.0TP53, ENO2

Graphical network of the top 20 diseases related to Carcinoid Tumor of Lung:



Diseases related to carcinoid tumor of lung

Clinical Features for Carcinoid Tumor of Lung

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Drugs & Therapeutics for Carcinoid Tumor of Lung

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Carcinoid Tumor of Lung

Search NIH Clinical Center for Carcinoid Tumor of Lung

Search CenterWatch for Carcinoid Tumor of Lung

Genetic Tests for Carcinoid Tumor of Lung

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Anatomical Context for Carcinoid Tumor of Lung

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32MalaCards
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MalaCards organs/tissues related to Carcinoid Tumor of Lung:

32
Lung

Animal Models for Carcinoid Tumor of Lung or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Carcinoid Tumor of Lung:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.5CALCA, CST3, MEN1, MIF
2MP:00036317.4TP53, ENO2, MEN1, NPY, CST3, CALCA
3MP:00053766.8TP53, GCG, CALCA, CST3, NPY, MEN1

Publications for Carcinoid Tumor of Lung

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Genetic Variations for Carcinoid Tumor of Lung

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Expression for genes affiliated with Carcinoid Tumor of Lung

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Carcinoid Tumor of Lung

Search GEO for disease gene expression data for Carcinoid Tumor of Lung.

Pathways for genes affiliated with Carcinoid Tumor of Lung

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Sources:
37NCBI BioSystems Database, 53Reactome, 12EMD Millipore
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Compounds for genes affiliated with Carcinoid Tumor of Lung

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Sources:
44Novoseek, 2BitterDB, 49PharmGKB, 11DrugBank, 24HMDB, 28IUPHAR, 59Tocris Bioscience
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Compounds related to Carcinoid Tumor of Lung according to GeneCards/GeneDecks:

(show top 50)    (show all 80)
idCompoundScoreTop Affiliating Genes
1estrogen4410.4GCG
2acetaminophen44 2 49 11 2414.3MIF
3norepinephrine44 11 2412.1NPY, CALCA
4amylinamide449.9IAPP, CALCA
5tesaglitazar449.9GCG, IAPP
6liraglutide44 28 1111.7GCG, IAPP
7exenatide44 1110.7GCG, IAPP
8calcitonin gene-related peptide449.7CALCA, NPY, IAPP
9enterostatin449.7GCG, NPY, IAPP
10incretin449.7IAPP, NPY, GCG
11muraglitazar49 4410.6GCG, IAPP
12helospectin449.6CALCA, NPY
13glibenclamide44 28 49 5912.6MIF, IAPP, CALCA
14sitagliptin44 1110.6IAPP, GCG
15streptozotocin449.6GCG, NPY, IAPP
16amphetamine44 1110.6IAPP, NPY, GCG
17i-app449.5GCG, CALCA, IAPP
18pramlintide44 1110.5GCG, CALCA, IAPP
192-deoxyglucose44 1110.4GCG, CALCA, NPY
20atropine44 28 1111.4NPY, CALCA, GCG
21ac 18744 5910.3IAPP, CALCA
22creatinine449.2IAPP, NPY, CST3, GCG
23isoflurane44 1110.2ENO2, NPY, CALCA
24corticosterone44 59 2411.1GCG, CALCA, NPY, MIF
25isoproterenol44 1110.1GCG, CALCA, NPY, IAPP
26serine449.1GCG, MEN1, IAPP, MIF
27epinephrine44 11 2411.0GCG, CALCA, NPY, IAPP
28histamine44 28 2411.0GCG, CALCA, NPY, IAPP
29catecholamine448.9ENO2, MIF, IAPP, NPY
30dopamine44 28 11 2411.8GCG, NPY, IAPP, ENO2
31carboplatin44 49 1110.8TP53, ENO2, CST3
32acth448.7CALCA, NPY, MIF, ENO2
33octreotide44 59 28 1111.7ENO2, NPY, CALCA, GCG
34tetrodotoxin44 59 2810.7GCG, CALCA, NPY, ENO2
35forskolin44 49 1110.7GCG, CALCA, NPY, ENO2
365-hydroxytryptamine448.7ENO2, NPY, CALCA, GCG
37ibmx44 28 5910.6GCG, CALCA, IAPP, ENO2
38arginine448.4TP53, IAPP, NPY, CST3, GCG
39guanine44 11 2410.3TP53, ENO2, CALCA, GCG
40indomethacin44 59 28 1111.3ENO2, IAPP, NPY, CALCA, GCG
41thymidine44 249.3MEN1, IAPP, MIF, ENO2, TP53
42acetylcholine44 49 28 11 2412.3GCG, CALCA, NPY, IAPP, ENO2
43nitric oxide44 11 2410.3CALCA, NPY, IAPP, MIF, ENO2
44adenylate448.3GCG, CALCA, NPY, IAPP, ENO2
45paraffin448.2NPY, MIF, ENO2, TP53
46alanine448.2GCG, CST3, NPY, MIF, ENO2
47glucose447.9GCG, CST3, NPY, IAPP, MIF, ENO2
48calcium44 49 11 2410.5CALCA, CST3, NPY, MEN1, IAPP, MIF
49lactate447.5ENO2, GCG, CALCA, CST3, NPY, IAPP
50vegf447.2CALCA, CST3, MEN1, MIF, ENO2, TP53

GO Terms for genes affiliated with Carcinoid Tumor of Lung

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16Gene Ontology
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Cellular components related to Carcinoid Tumor of Lung according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055767.8CALCA, CST3, NPY, IAPP, MIF, GCG
2extracellular spaceGO:0056157.5MIF, IAPP, NPY, CST3, CALCA, GCG

Biological processes related to Carcinoid Tumor of Lung according to GeneCards/GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of bone resorptionGO:0457799.7CALCA, IAPP
2positive regulation of protein bindingGO:0320929.6MEN1, GCG
3regulation of tissue remodelingGO:0341039.6TP53, CST3
4DNA damage response, signal transduction by p53 class mediatorGO:0303309.5TP53, MIF
5cell agingGO:0075699.4TP53, MIF
6response to gamma radiationGO:0103329.4MEN1, TP53
7feeding behaviorGO:0076319.3NPY, CALCA, GCG
8positive regulation of cAMP biosynthetic processGO:0308199.1CALCA, GCG
9cell proliferationGO:0082838.7GCG, NPY, MIF, TP53

Molecular functions related to Carcinoid Tumor of Lung according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051798.8GCG, CALCA, IAPP
2identical protein bindingGO:0428028.4TP53, IAPP, CALCA, GCG
3receptor bindingGO:0051028.2MIF, IAPP, NPY, CALCA, GCG

Products for genes affiliated with Carcinoid Tumor of Lung

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Sources for Carcinoid Tumor of Lung

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet