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12Gene Ontology
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Cellular components related to carcinoma according to GeneDecks: (show all 25)
| id | Name | GO ID | Score | Top Affiliating Genes | | 1 | extracellular space | GO:005615 | INF | , KL, REG3A, RELN, REN, CNTF | | 2 | neuronal cell body | GO:043025 | INF | PI4K2A, NCOA2, CNTF, CNTN2, SERPINE2, BRS3 | | 3 | nucleoplasm | GO:005654 | INF | ZNF217, PIAS1, PIN1, RFC1, RFC4, RFC5 | | 4 | plasma membrane | GO:005886 | INF | PIK3CD, PIK3R1, PIK3C2B, PIK3C2A, PIK3CG, PIGU | | 5 | apical plasma membrane | GO:016324 | INF | PIP, , SEPT7, BST2, NAALADL1, BMPR2 | | 6 | extracellular region | GO:005576 | INF | PIGR, PIP, LRPAP1, KL, NCAM1, PDCD1LG2 | | 7 | cytoplasm | GO:005737 | INF | ZNF146, PIAS3, PIR, PIM3, PIK3R5, PIDD | | 8 | integral to plasma membrane | GO:005887 | INF | PIGR, PI4K2A, LRP1, LRP12, LRRC32, KL | | 9 | perinuclear region of cytoplasm | GO:048471 | 55.7 | PIKFYVE, LRAT, PDE4A, PCSK9, BUB1B, GC | | 10 | external side of plasma membrane | GO:009897 | 38.0 | NCAM1, KIT, VWF, SELL, SELP, SERPINA5 | | 11 | transcription factor complex | GO:005667 | 32.3 | KLF4, RELA, RBL2, RBM14, NAA15, LMO2 | | 12 | membrane raft | GO:045121 | 29.9 | PIKFYVE, PI4K2A, SGCA, BTK, SELE, BSG | | 13 | basolateral plasma membrane | GO:016323 | 28.9 | LIN7C, UMOD, CHRM3, P2RY1, P2RY2, P2RY4 | | 14 | focal adhesion | GO:005925 | 27.0 | ZNF384, RFWD2, KIF22, BRCA1, LPP, LPXN | | 15 | cell-cell junction | GO:005911 | 24.7 | SGCA, VCL, RAP1B, CLDN5, CLIC4, PAK1 | | 16 | platelet alpha granule lumen | GO:031093 | 20.4 | VWF, SERPINF2, SERPINA1, SERPINE1, SERPING1, VEGFA | | 17 | endoplasmic reticulum | GO:005783 | INF | PIK3C2B, , LRP6, LRPAP1, NCEH1, NCK1 | | 18 | cytosol | GO:005829 | INF | PIKFYVE, PIK3CB, PIK3CD, PI4K2A, PIK3CA, PIK3R3 | | 19 | nucleolus | GO:005730 | INF | ZNF146, ZNF148, ZNF384, ZNF207, PINX1, KLF5 | | 20 | membrane | GO:016020 | INF | PIK3R5, PIK3CG, RFFL, PDE3B, PDE4A, RECK | | 21 | cell surface | GO:009986 | INF | LRP6, LRPAP1, NCAM1, CNTN2, KISS1R, SFRP1 | | 22 | nucleus | GO:005634 | INF | ZNF444, ZNF197, ZNF510, ZNF267, ZNF382, ZNF410 | | 23 | proteinaceous extracellular matrix | GO:005578 | INF | PI3, RELN, VWF, SFRP1, SERPINA1, VEGFA | | 24 | extracellular matrix | GO:031012 | INF | VWF, VTN, SFRP1, SFRP2, PCSK6, SERPINE2 | | 25 | mitochondrion | GO:005739 | INF | PI4K2A, PINX1, RERE, KIF1B, KIAA0101, PCK2 |
Biological processes related to carcinoma according to GeneDecks: (show top 50)
(show all 101)
| id | Name | GO ID | Score | Top Affiliating Genes | | 1 | aging | GO:007568 | INF | , KL, NCF2, CNR1, SERPINA7, SERPINF1 | | 2 | response to hypoxia | GO:001666 | INF | SFTPB, SERPINA1, VEGFA, VCAM1, BNIP3, MYOCD | | 3 | signal transduction | GO:007165 | 124.5 | PIK3CB, PIK3CD, PIDD, LRP12, SH3BP2, SH3GL2 | | 4 | blood coagulation | GO:007596 | 71.6 | PIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, PIK3R5 | | 5 | cell adhesion | GO:007155 | 65.4 | NCAM1, RELN, CNTN2, KITLG, VWF, VTN | | 6 | immune response | GO:006955 | 53.3 | NCR3, PDCD1LG2, CNR2, KIR2DS5, KIR2DL1, KIR2DL3 | | 7 | innate immune response | GO:045087 | 52.4 | PIK3CD, PIK3CG, PIN1, NCF2, RELA, SFTPD | | 8 | inflammatory response | GO:006954 | 50.8 | PIK3CD, PIK3CG, NCR3, RELA, CNR2, KIT | | 9 | protein phosphorylation | GO:006468 | 49.7 | PIK3CD, PIM2, PIM3, PIM1, RET, VRK1 | | 10 | anti-apoptosis | GO:006916 | 45.2 | PIM2, PIK3CA, SH3GLB1, RELA, GCLC, SERPINB9 | | 11 | platelet activation | GO:030168 | 44.6 | PIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, PIK3R5 | | 12 | positive regulation of apoptotic process | GO:043065 | 44.4 | LRP6, NCOA1, REST, CNR1, KIAA1967, SFRP1 | | 13 | angiogenesis | GO:001525 | 42.1 | PIK3CA, PIK3CG, KLF5, NCL, PDE3B, WARS | | 14 | nerve growth factor receptor signaling pathway | GO:048011 | 41.6 | PIK3CB, PIK3CA, PIK3R2, PIK3R1, SH3GL2, NDN | | 15 | mitotic cell cycle | GO:000278 | 41.4 | NDC80, RFC1, RFC4, RFC5, KIF23, RCC2 | | 16 | cytokine-mediated signaling pathway | GO:019221 | 40.7 | PIAS1, PIN1, KLF6, NCAM1, RELA, KIT | | 17 | induction of apoptosis | GO:006917 | 39.2 | KLF10, PDCD5, PCSK9, NACC1, NAIF1, BOK | | 18 | transcription initiation from RNA polymerase II promoter | GO:006367 | 35.3 | NCOR1, NCOR2, RBPJ, RBL1, SERPINE1, VDR | | 19 | cell surface receptor signaling pathway | GO:007166 | 34.3 | BSG, MYD88, LIFR, BIRC2, BIRC3, KHDRBS1 | | 20 | positive regulation of cell migration | GO:030335 | 32.4 | RET, VIL1, VEGFA, MYLK, BMP2, KDR | | 21 | protein autophosphorylation | GO:046777 | 32.1 | PIM1, KIT, VRK1, VRK2, BMX, CLK1 | | 22 | epidermal growth factor receptor signaling pathway | GO:007173 | 31.7 | PIK3CA, PIK3R1, PIK3C2A, SH3GL2, PDE1A, PDE1C | | 23 | regulation of apoptotic process | GO:042981 | 31.5 | KIAA1324, SEPT4, BRCA1, VCP, LMNA, RAF1 | | 24 | cell cycle arrest | GO:007050 | 31.5 | BTG4, RB1, NBN, SESN1, VASH1, MYC | | 25 | insulin receptor signaling pathway | GO:008286 | 31.2 | PIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, PIK3C2A | | 26 | positive regulation of I-kappaB kinase/NF-kappaB cascade | GO:043123 | 30.6 | PIM2, REL, RELA, BST2, LPAR1, MYD88 | | 27 | transforming growth factor beta receptor signaling pathway | GO:007179 | 30.0 | KLF10, NCOR1, NCOR2, RBL1, SERPINE1, MYC | | 28 | fibroblast growth factor receptor signaling pathway | GO:008543 | 29.5 | PIK3CA, PIK3R1, KL, PDE1A, PDE1C, BRAF | | 29 | leukocyte migration | GO:050900 | 29.4 | PIK3CB, PIK3CA, PIK3R2, PIK3R1, SELL, SELP | | 30 | platelet degranulation | GO:002576 | 27.4 | VWF, SELP, SERPINF2, SERPINA1, SERPINE1, SERPING1 | | 31 | positive regulation of NF-kappaB transcription factor activity | GO:051092 | 26.9 | RELA, BTK, MYD88, CLU, BCL10, CHUK | | 32 | activation of cysteine-type endopeptidase activity involved in apoptotic process | GO:006919 | 25.2 | PDCD6, VCP, BOK, MYC, BCL2L10, BCL2L11 | | 33 | Toll signaling pathway | GO:008063 | 25.1 | RELA, BTK, MYD88, CHUK, UBB, UBC | | 34 | cellular response to hypoxia | GO:071456 | 24.4 | SFRP1, RBX1, VLDLR, VHL, VEGFA, LMNA | | 35 | positive regulation of peptidyl-tyrosine phosphorylation | GO:050731 | 23.7 | RELN, KITLG, VTN, VEGFA, VEGFB, LIF | | 36 | DNA repair | GO:006281 | INF | RFC1, RFC4, RFC5, RECQL, RECQL4, REV1 | | 37 | heart development | GO:007507 | INF | PCNA, RBP4, RB1CC1, VLDLR, VCAM1, VCAN | | 38 | positive regulation of cell proliferation | GO:008284 | INF | KLF5, REG1A, CNBP, CNTF, KIT, SFRP1 | | 39 | positive regulation of transcription from RNA polymerase II promoter | GO:045944 | INF | ZNF148, LRP6, KLF4, KLF6, NCK1, NCOA1 | | 40 | cell proliferation | GO:008283 | INF | PIM2, PIM1, , KLF10, REG3A, RETNLB | | 41 | small molecule metabolic process | GO:044281 | INF | PIKFYVE, PIK3CB, PIK3CD, PI4K2A, PIK3CA, PIK3R3 | | 42 | negative regulation of apoptotic process | GO:043066 | INF | PIM3, PIDD, PIK3CG, PIM1, PDE3A, RELA | | 43 | positive regulation of transcription, DNA-dependent | GO:045893 | INF | PIM2, PIAS1, LRP6, KLF4, KLF5, KLF6 | | 44 | virus-host interaction | GO:019048 | INF | PIK3R1, RELA, SGTA, VRK2, BUB1, BTRC | | 45 | gene expression | GO:010467 | INF | NCOR1, NCOR2, WARS, WARS2, PCBP2, RBM5 | | 46 | response to lipopolysaccharide | GO:032496 | INF | NCF2, CNR1, CNR2, SFTPB, SFTPC, SELE | | 47 | response to drug | GO:042493 | INF | , NCF2, PDE3A, PDE4A, REN, SFRP1 | | 48 | response to estradiol stimulus | GO:032355 | INF | NCOA1, SFRP4, GC, SERPINA1, BRCA2, VDR | | 49 | negative regulation of cell growth | GO:030308 | INF | RERG, SFRP1, SFRP2, RB1, SERPINE2, SERTAD3 | | 50 | negative regulation of cell proliferation | GO:008285 | INF | PIM2, PINX1, KLF10, KLF4, NDN, RERG |
Molecular functions related to carcinoma according to GeneDecks: (show all 28)
| id | Name | GO ID | Score | Top Affiliating Genes | | 1 | receptor activity | GO:004872 | INF | LRP1, RET, KIR2DL1, KIR2DL3, SEMA3A, SEMA3E | | 2 | protein binding | GO:005515 | INF | ZNF217, ZNF148, ZNF652, ZNF639, PIKFYVE, PIK3CB | | 3 | protein homodimerization activity | GO:042803 | 75.5 | LRP6, SH3GLB1, PDCD6, KIT, VWF, SFTPC | | 4 | protein kinase binding | GO:019901 | 46.4 | RELA, KIF11, RB1CC1, VIM, RAD9A, LLGL1 | | 5 | transcription factor binding | GO:008134 | 41.2 | PIM1, RELA, REST, RB1, RBL1, NBN | | 6 | protein serine/threonine kinase activity | GO:004674 | 41.0 | PIM2, PIK3CA, PIM3, PIK3CG, PIM1, VRK1 | | 7 | growth factor activity | GO:008083 | 39.2 | REG1A, CNTF, KITLG, BTC, VGF, VEGFA | | 8 | chromatin binding | GO:003682 | 36.3 | NCOA1, NCOA2, NCOA3, RELA, REST, RCC1 | | 9 | transcription regulatory region DNA binding | GO:044212 | 35.6 | ZNF217, ZNF639, KLF4, NCOR1, RELA, REST | | 10 | signal transducer activity | GO:004871 | 34.8 | KL, NCOA1, NCOA2, NCOA3, PDCD1, VOPP1 | | 11 | protein kinase activity | GO:004672 | 33.3 | PIK3CG, BUB1, BUB1B, BRAF, RAF1, LIMK1 | | 12 | structural molecule activity | GO:005198 | 29.8 | NCR3LG1, BVES, SEMG2, SEPT4, SEPT7, VCL | | 13 | heparin binding | GO:008201 | 29.6 | ZNF146, LRPAP1, VTN, SFRP1, PCSK6, SELL | | 14 | ubiquitin protein ligase binding | GO:031625 | 29.4 | RELA, PCBP2, RB1, RBX1, BRCA1, MYOD1 | | 15 | electron carrier activity | GO:009055 | 28.1 | NCF2, UQCR11, SDHB, SDHC, SDHD, UGDH | | 16 | hormone activity | GO:005179 | 24.7 | KL, RETN, RETNLB, GCG, VIP, UTS2 | | 17 | double-stranded DNA binding | GO:003690 | 24.4 | ZNF148, KLF4, KLF6, MYC, RAD51, RAD51AP1 | | 18 | protein tyrosine kinase activity | GO:004713 | 24.0 | RET, KIT, BTK, LMTK3, BMX, KDR | | 19 | beta-catenin binding | GO:008013 | 21.6 | BTRC, VCL, BCL9, BCL9L, LEF1, SALL1 | | 20 | sequence-specific DNA binding | GO:043565 | INF | ZNF148, RERE, NANOG, VDR, MYC, RARG | | 21 | identical protein binding | GO:042802 | INF | SH3GL2, SH3GLB1, RELA, CNTN2, SFRP1, PCSK9 | | 22 | enzyme binding | GO:019899 | INF | PIAS3, PIAS1, RFC5, NCOA1, KIAA1967, PCBP2 | | 23 | receptor binding | GO:005102 | INF | LRP6, NCK1, REN, RCHY1, GCG, SELPLG | | 24 | calcium ion binding | GO:005509 | INF | LRP1B, LRP1, , PDCD6, RET, SGCA | | 25 | cytokine activity | GO:005125 | INF | CNTF, KITLG, NAMPT, VEGFA, BMP1, BMP2 | | 26 | ATP binding | GO:005524 | INF | PIKFYVE, PIK3CB, PIK3CD, PI4K2A, PIM2, PIK3CA | | 27 | sequence-specific DNA binding transcription factor activity | GO:003700 | INF | ZNF444, ZNF197, ZNF217, ZNF148, ZNF202, ZNF135 | | 28 | protein heterodimerization activity | GO:046982 | INF | BRAF, VEGFA, VEGFB, BOK, BNIP3, BNIP3L |
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