Aliases & Classifications for Cardiac Arrest

MalaCards integrated aliases for Cardiac Arrest:

Name: Cardiac Arrest 12 72 28 51 40 14 69
Cardiopulmonary Arrest 12 51 69
Circulatory Arrest 12 69
Heart Arrest 41

Classifications:



Summaries for Cardiac Arrest

MedlinePlus : 40 The heart has an internal electrical system that controls the rhythm of the heartbeat. Problems can cause abnormal heart rhythms, called arrhythmias. There are many types of arrhythmia. During an arrhythmia, the heart can beat too fast, too slow, or it can stop beating. Sudden cardiac arrest (SCA) occurs when the heart develops an arrhythmia that causes it to stop beating. This is different than a heart attack, where the heart usually continues to beat but blood flow to the heart is blocked. There are many possible causes of SCA. They include coronary heart disease, physical stress, and some inherited disorders. Sometimes there is no known cause for the SCA. Without medical attention, the person will die within a few minutes. People are less likely to die if they have early defibrillation. Defibrillation sends an electric shock to restore the heart rhythm to normal. You should give cardiopulmonary resuscitation (CPR) to a person having SCA until defibrillation can be done. If you have had an SCA, an implantable cardiac defibrillator (ICD) reduces the chance of dying from a second SCA. NIH: National Heart, Lung, and Blood Institute

MalaCards based summary : Cardiac Arrest, also known as cardiopulmonary arrest, is related to ventricular fibrillation, paroxysmal familial, 1 and cardiac conduction defect, and has symptoms including edema, chest pain and angina pectoris. An important gene associated with Cardiac Arrest is CASQ2 (Calsequestrin 2), and among its related pathways/superpathways are Cardiac conduction and Neuroscience. The drugs Clonazepam and Valproic Acid have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and lung, and related phenotypes are Decreased Hepatitis C Virus pseudoparticles (HCVpp and behavior/neurological

Disease Ontology : 12 A congestive heart failure characterized by a sudden stop in effective blood circulation due to the failure of the heart to contract effectively or at all.

Wikipedia : 72 Cardiac arrest is a sudden loss of blood flow resulting from the failure of the heart to effectively... more...

Related Diseases for Cardiac Arrest

Diseases related to Cardiac Arrest via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 267)
# Related Disease Score Top Affiliating Genes
1 ventricular fibrillation, paroxysmal familial, 1 32.1 KCNQ1 RYR2 SCN5A TNNT2
2 cardiac conduction defect 31.9 MYH7 RYR2 SCN5A
3 andersen cardiodysrhythmic periodic paralysis 31.6 KCNQ1 RYR2 SCN5A
4 myocardial infarction 31.0 ACE ALB CKB PIK3C2A S100B TNNT2
5 long qt syndrome 1 30.8 CALM1 CALM3 CASQ2 KCNQ1 RYR2 SCN5A
6 ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy 30.6 CASQ2 KCNQ1 MYH7 RYR2 SCN5A TRDN
7 syncope 30.3 CALM1 KCNQ1 SCN5A
8 arteries, anomalies of 30.2 ACE ALB TNNT2
9 long qt syndrome 30.0 CALM1 CALM3 KCNQ1 RYR2 SCN5A
10 acute myocardial infarction 29.8 ACE CKB PIK3C2A TNNT2
11 cardiac arrhythmia 29.7 KCNQ1 RYR2 SCN5A
12 hypertrophic cardiomyopathy 29.7 ACE MYH7 RYR2 TNNT2
13 respiratory failure 29.4 ACE ALB PIK3C2A
14 atrial fibrillation 29.4 ACE KCNQ1 RYR2 SCN5A
15 atrioventricular block 29.4 KCNQ1 PIK3C2A SCN5A
16 catecholaminergic polymorphic ventricular tachycardia 29.1 CALM1 CALM3 CASQ2 KCNQ1 RYR2 SCN5A
17 left ventricular noncompaction 28.9 KCNQ1 MYH7 RYR2 SCN5A TNNT2
18 atrial standstill 1 28.9 ACE MYH7 SCN5A SLC25A20 TNNT2
19 dilated cardiomyopathy 27.8 ACE ALB KCNQ1 MYH7 RYR2 SCN5A
20 heart disease 26.9 ACE ALB AVP KCNQ1 MYH7 PIK3C2A
21 hypoxia 11.2
22 pulmonary edema 11.2
23 anoxia 11.2
24 cerebral hypoxia 11.2
25 wolff-parkinson-white syndrome 11.2
26 orthostatic intolerance 11.2
27 eclampsia 11.2
28 cyanide poisoning 11.2
29 cardiomyopathy, infantile histiocytoid 11.1
30 jervell and lange-nielsen syndrome 1 11.0
31 ventricular tachycardia, catecholaminergic polymorphic, 3 11.0
32 coronary artery dissection, spontaneous 10.8
33 ventricular tachycardia, catecholaminergic polymorphic, 2 10.8
34 ventricular tachycardia, catecholaminergic polymorphic, 4 10.8
35 ventricular tachycardia, catecholaminergic polymorphic, 5, with or without muscle weakness 10.8
36 sudden cardiac failure, infantile 10.8
37 sudden cardiac failure, alcohol-induced 10.8
38 arrhythmogenic right ventricular cardiomyopathy 10.8
39 myocarditis 10.8
40 intracranial cysts 10.5 ENO2 S100B
41 acute dacryocystitis 10.5 CALM1 CALM3
42 bednar tumor 10.5 ENO2 S100B
43 long qt syndrome 15 10.5 CALM1 CALM3
44 external ear disease 10.5 CALM1 CALM3
45 epithelioid malignant peripheral nerve sheath tumor 10.5 ENO2 S100B
46 arrhythmogenic right ventricular dysplasia, familial, 2 10.5 CASQ2 RYR2
47 middle cerebral artery infarction 10.5 ENO2 S100B
48 ossifying fibromyxoid tumor 10.5 ENO2 S100B
49 otitis externa 10.5 CALM1 CALM3
50 neonatal hypoxic and ischemic brain injury 10.4 CKB ENO2

Comorbidity relations with Cardiac Arrest via Phenotypic Disease Network (PDN): (show all 33)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Myocardial Infarction
Aortic Aneurysm Aortic Valve Disease 1
Bronchitis Cardiogenic Shock
Chronic Kidney Failure Chronic Myocardial Ischemia
Decubitus Ulcer Deficiency Anemia
Disseminated Intravascular Coagulation Familial Atrial Fibrillation
First-Degree Atrioventricular Block Generalized Atherosclerosis
Heart Disease Hypertension, Essential
Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis Syndrome Intermediate Coronary Syndrome
Ischemic Heart Disease Kidney Disease
Mitral Valve Disease Ocular Motor Apraxia
Peripheral Vascular Disease Progressive Familial Heart Block, Type Ia
Protein-Energy Malnutrition Pulmonary Hypertension, Primary, 1
Respiratory Failure Sinoatrial Node Disease
Third-Degree Atrioventricular Block Tricuspid Valve Disease
Ventricular Fibrillation, Paroxysmal Familial, 1

Graphical network of the top 20 diseases related to Cardiac Arrest:



Diseases related to Cardiac Arrest

Symptoms & Phenotypes for Cardiac Arrest

UMLS symptoms related to Cardiac Arrest:


edema, chest pain, angina pectoris

GenomeRNAi Phenotypes related to Cardiac Arrest according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased Hepatitis C Virus pseudoparticles (HCVpp GR00234-A-1 8.8 CALM3 CKB PIK3C2A

MGI Mouse Phenotypes related to Cardiac Arrest:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.9 TRDN ACE AVP CKB CYCS ENO2
2 cardiovascular system MP:0005385 9.65 ACE CASQ2 CYCS KCNQ1 MYH7 PIK3C2A
3 muscle MP:0005369 9.23 ALB CASQ2 KCNQ1 MYH7 RYR2 SCN5A

Drugs & Therapeutics for Cardiac Arrest

Drugs for Cardiac Arrest (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 672)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
2
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
3
Lorazepam Approved Phase 4 846-49-1 3958
4
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 2078-54-8 4943
5
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 51-43-4 5816
6 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1 329-65-7
7
Ticagrelor Approved Phase 4 274693-27-5 9871419
8
Meperidine Approved Phase 4 57-42-1 4058
9
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
10
Ephedrine Approved Phase 4,Phase 2,Phase 3 299-42-3 9294
11
Norepinephrine Approved Phase 4 51-41-2 439260
12
Oxymetazoline Approved, Investigational Phase 4 1491-59-4 4636
13
Phenylephrine Approved Phase 4 59-42-7 6041
14
Pseudoephedrine Approved Phase 4,Phase 2,Phase 3 90-82-4 7028
15
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
16
Ethanol Approved Phase 4,Phase 2 64-17-5 702
17
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
18
Ofloxacin Approved Phase 4 82419-36-1 4583
19
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2 137-58-6 3676
20
Mannitol Approved, Investigational Phase 4,Phase 2 69-65-8 6251 453
21
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
22
Midazolam Approved, Illicit Phase 4,Phase 3 59467-70-8 4192
23
Remifentanil Approved Phase 4,Phase 3 132875-61-7 60815
24
Misoprostol Approved Phase 4,Phase 1 59122-46-2 5282381
25
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613 2171
26
Ticlopidine Approved Phase 4 55142-85-3 5472
27
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 16590-41-3 5360515
28
Anastrozole Approved, Investigational Phase 4,Phase 2 120511-73-1 2187
29
Tamoxifen Approved Phase 4 10540-29-1 2733526
30
Nifedipine Approved Phase 4 21829-25-4 4485
31
Ritodrine Approved, Investigational Phase 4 26652-09-5 33572
32
Atropine Approved, Vet_approved Phase 4,Phase 2 5908-99-6, 51-55-8 174174
33
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
34
Simvastatin Approved Phase 4,Phase 3 79902-63-9 54454
35
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
36
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
37
Moxifloxacin Approved, Investigational Phase 4 151096-09-2, 354812-41-2 152946
38
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
39
Fluvastatin Approved Phase 4 93957-54-1 1548972
40
Angiotensin II Approved, Investigational Phase 4,Phase 2 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
41
Salicylic acid Approved, Investigational, Vet_approved Phase 4 69-72-7 338
42
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
43
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 5311068 56032 68602
44
Ropivacaine Approved Phase 4 84057-95-4 175805 71273
45
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
46
Letrozole Approved, Investigational Phase 4,Phase 2,Phase 1 112809-51-5 3902
47
Thrombin Approved, Investigational Phase 4,Phase 3
48
Progesterone Approved, Vet_approved Phase 4,Phase 2,Phase 3 57-83-0 5994
49
Pioglitazone Approved, Investigational Phase 4,Phase 2,Phase 3 111025-46-8 4829
50
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795

Interventional clinical trials:

(show top 50) (show all 1214)

# Name Status NCT ID Phase Drugs
1 The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild Hypothermia Unknown status NCT01083784 Phase 4 Use of prophylactic anticonvulsants (valproate, clonazepam);Control group
2 Therapeutic Hypothermia With Propofol in Survival and Neurological Prognoses After Cardiac Arrest Unknown status NCT02367755 Phase 4 Propofol;Lorazepam
3 Sodium Bicarbonate in Cardiopulmonary Resuscitation Unknown status NCT01377337 Phase 4 sodium bicarbonate
4 Effects and Plasma Concentration of Ticagrelor, After Crushed and Non-crushed Intake, After Acute Coronary Syndrome Unknown status NCT02341729 Phase 4 ticagrelor
5 Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women Unknown status NCT01555671 Phase 4 Placebo;Meperidine
6 Early Feeding Following Ligation of Acute Bleeding Varices Unknown status NCT01287702 Phase 4
7 Out-of Hospital Resuscitation Study Unknown status NCT00196248 Phase 4
8 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4 Ivabradine;Placebo
9 IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction Unknown status NCT00157768 Phase 4
10 Effects of Preconditioning With Sevoflurane During Organ Procurement From Brain Dead Donors: Impact on Early Function of Liver Allografts Unknown status NCT02341833 Phase 4 Sevoflurane
11 CERAMENT™|G - Bone Healing and Re-infection Prophylaxis Unknown status NCT02128256 Phase 4
12 Arrhythmia Restart Prevention and RatE STabilization in Atrial Fibrillation Unknown status NCT00224341 Phase 4
13 Role of FSHR Polymorphism p.N680S in the Therapy With FSH in Patients Who Underwent Varicocele Surgery Unknown status NCT02719093 Phase 4 recombinant FSH
14 A Pilot Trial of Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients Unknown status NCT02203630 Phase 4 Phenylephrine;Norepinephrine
15 Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest Completed NCT02899507 Phase 4 Amoxicillin-Clavulanic acid
16 Vasopressin and Epinephrine Versus Epinephrine Alone in Cardiac Arrest Completed NCT00127907 Phase 4 epinephrine (1 mg/1 mL);arginine-vasopressin (40 UI/2 mL)
17 Continuous Chest Compressions vs AHA Standard CPR of 30:2 Completed NCT01372748 Phase 4
18 Comparing Therapeutic Hypothermia Using External and Internal Cooling for Post-Cardiac Arrest Patients Completed NCT00827957 Phase 4
19 Clinical and Economical Interest of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA Study) Completed NCT00392639 Phase 4
20 Antiplatelet Therapy After Cardiac Arrest Completed NCT02224274 Phase 4 Clopidogrel;Ticagrelor
21 Trial of Different Hypothermia Temperatures in Patients Recovered From Out-of-hospital Cardiac Arrest Completed NCT01155622 Phase 4
22 COOL-Trial: Outcome With Invasive and Non-invasive Cooling After Cardiac Arrest Completed NCT00843297 Phase 4
23 Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest Completed NCT01369732 Phase 4 recombinant human erythropoietin;saline
24 Cardiopulmonary Resuscitation Witnessing by a Relative Completed NCT01009606 Phase 4
25 Quick ICD Study: Is Extensive Electrophysiological Testing Before, During and After ICD-Implantation Still Necessary ? Completed NCT00180362 Phase 4
26 Beating Versus Arrested Heart for Mitral Valve Replacement Completed NCT01641614 Phase 4
27 Transthoracic Incremental Monophasic Versus Biphasic by Emergency Responders (TIMBER) Completed NCT00101881 Phase 4
28 A Study of VIVITROL in the Prevention of Re-arrest and Re-incarceration Completed NCT01453374 Phase 4 VIVITROL 380mg
29 Neuron Specific Enolase (NSE) as Outcome Parameter of Cooling Therapy After Survived Sudden Cardiac Death Completed NCT01102153 Phase 4
30 Arimidex Observational: Reason for and Effect of Change From Tamoxifen Completed NCT00246961 Phase 4
31 Multicenter Automatic Defibrillator Implantation Trial - Reduce Inappropriate Therapy Completed NCT00947310 Phase 4
32 Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion Completed NCT00454428 Phase 4
33 Comparative Study Between Nifedipine and Ritodrine as Maintenance Tocolytic Therapy in Preterm Labor Completed NCT03040752 Phase 4 Nifedipine 20 Mg;Ritodrine Oral Tablet
34 ISSUE3: International Study on Syncope of Uncertain Etiology 3 Completed NCT00359203 Phase 4
35 The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions Completed NCT02953886 Phase 4
36 Atropine for Prevention of Dysrhythmias Caused by Percutaneous Ethanol Instillation for Hepatoma Therapy Completed NCT00575523 Phase 4 Atropine;Placebo
37 The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial Completed NCT00430989 Phase 4 Nitrous Oxide;Nitrous Oxide
38 Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHD Completed NCT00159835 Phase 4 atorvastatin;simvastatin
39 Avelox for Treatment of Elderly Patients With Community Acquired Pneumonia Completed NCT00665327 Phase 4 Avelox (Moxifloxacin, BAY12-8039);Levofloxacin
40 Study of Mechanisms of Anovulation in Polycystic Ovary Syndrome Completed NCT00492882 Phase 4 usual administration of exogenous recombinant FSH
41 Out-of-Hospital Intubation With Metal Single Use Laryngoscope Blades Completed NCT00644722 Phase 4
42 Fluvastatin in the Therapy of Acute Coronary Syndrome Completed NCT00171275 Phase 4 Fluvastatin
43 Heart Outcomes Prevention Evaluation-3 Completed NCT00468923 Phase 4 Candesartan/HCT;Rosuvastatin
44 Preventive and Therapeutic Proximal Sealants Completed NCT02338180 Phase 4
45 Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke Completed NCT00147602 Phase 4 atorvastatin
46 CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events Completed NCT00327418 Phase 4 Atorvastatin
47 The Effect of Nitroglycerin Infusion Rate on Cerebral Rewarming During Hypothermic Coronary Artery Bypass Grafting Completed NCT03251599 Phase 4 Glyceryl trinitrate 0.2;Glyceryl trinitrate 0.5
48 Addition of Dexmedetomidine to Ropivacaine-induced Supraclavicular Block (ADRIB Trial) Completed NCT02630290 Phase 4 Ropivacaine;Ropivacaine + Dexmedetomidine
49 Clinical Trial to Evaluate the Use of an Adsorption Membrane (OXIRIS®) During Cardiopulmonary Bypass Surgery Completed NCT02398019 Phase 4
50 Aromatase Inhibitor Effects on Ovarian Function During the Follicular and Early Luteal Phase in Women Completed NCT01046578 Phase 4 Letrozole;Letrozole;Letrozole;Letrozole;Letrozole;Letrozole

Search NIH Clinical Center for Cardiac Arrest

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: heart arrest

Genetic Tests for Cardiac Arrest

Genetic tests related to Cardiac Arrest:

# Genetic test Affiliating Genes
1 Cardiac Arrest 28

Anatomical Context for Cardiac Arrest

MalaCards organs/tissues related to Cardiac Arrest:

38
Heart, Brain, Lung, Testes, Breast, Kidney, Bone

Publications for Cardiac Arrest

Articles related to Cardiac Arrest:

(show top 50) (show all 481)
# Title Authors Year
1
Cardiac arrest and ventricular arrhythmia in adults with Ebstein anomaly and left ventricular non-compaction. ( 29305187 )
2018
2
Association Between Early Hyperoxia Exposure After Resuscitation from Cardiac Arrest and Neurological Disability: A Prospective Multi-Center Protocol-Directed Cohort Study. ( 29437118 )
2018
3
Survival factors of hospitalized out-of-hospital cardiac arrest patients in Taiwan: A retrospective study. ( 29420551 )
2018
4
Survival after out-of-hospital cardiac arrest in nursing homes - A nationwide study. ( 29425977 )
2018
5
Cyanide poisoning is a possible cause of cardiac arrest among fire victims, and empiric antidote treatment may improve outcomes. ( 29395761 )
2018
6
Effect of target temperature management at 32-34a8^A^C in cardiac arrest patients considering assessment by regional cerebral oxygen saturation: A multicenter retrospective cohort study. ( 29432783 )
2018
7
"Resuscitation time bias"-A unique challenge for observational cardiac arrest research. ( 29425975 )
2018
8
The Role of Cranial Temperature in Neuroprotection by Sodium Hydrogen Sulfide After Cardiac Arrest in Mice. ( 29431591 )
2018
9
Changes in left ventricular systolic and diastolic function on serial echocardiography after out-of-hospital cardiac arrest. ( 29438721 )
2018
10
Ocular bobbing/dipping after cardiac arrest may be a post-anoxic myoclonus. ( 29307541 )
2018
11
Is Distance to the Nearest Registered Public Automated Defibrillator Associated with the Probability of Bystander Shock for Victims of Out-of-Hospital Cardiac Arrest? ( 29433603 )
2018
12
Atherothrombotic out-of hospital cardiac arrest: watch out for a second train. ( 29437817 )
2018
13
Stability of Early EEG Background Patterns After Pediatric Cardiac Arrest. ( 29443794 )
2018
14
Activation of Sigma-1 Receptor by Cutamesine Attenuates Neuronal Apoptosis by Inhibiting Endoplasmic Reticulum Stress and Mitochondrial Dysfunction in a Rat Model of Asphyxia Cardiac Arrest. ( 29424796 )
2018
15
EEG Factors After Pediatric Cardiac Arrest. ( 29438177 )
2018
16
Novel relocation methods for automatic external defibrillator improve out-of-hospital cardiac arrest coverage under limited resources. ( 29414670 )
2018
17
Epidemiology of Pediatric Out-of-Hospital Cardiac Arrest at Schoola88- An Investigation of a Nationwide Registry in Japan. ( 29445066 )
2018
18
Design of DISCO-Direct or Subacute Coronary Angiography in Out-of-Hospital Cardiac Arrest study. ( 29447784 )
2018
19
Non-invasive characterization of hemodynamics in adult out-of-hospital cardiac arrest patients soon after return of spontaneous circulation. ( 29425976 )
2018
20
Comparative Safety of Sulfonylureas and the Risk of Sudden Cardiac Arrest and Ventricular Arrhythmia. ( 29437823 )
2018
21
The Use of ECMO for the Treatment of Refractory Cardiac Arrest or Postarrest Cardiogenic Shock Following In-Hospital Cardiac Arrest: A 10-Year Experience. ( 29303029 )
2018
22
Late heartbeat-evoked potentials are associated with survival after cardiac arrest. ( 29447999 )
2018
23
Global Registry of Acute Coronary Events risk score predicts mortality and neurological outcome in out-of hospital cardiac arrest. ( 28082161 )
2017
24
Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest. ( 28934276 )
2017
25
Successful early application of extracorporeal membrane oxygenation to support cardiopulmonary resuscitation for a patient suffering from severe malignant hyperthermia and cardiac arrest: a case report. ( 28580087 )
2017
26
Systemic impact on secondary brain aggravation due to ischemia/reperfusion injury in post-cardiac arrest syndrome: a prospective observational study using high-mobility group box 1 protein. ( 28950909 )
2017
27
Cardiac arrest related to anaesthesia in Williams-Beuren syndrome. ( 29246395 )
2017
28
Resuscitation of prolonged cardiac arrest from massive pulmonary embolism by extracorporeal membrane oxygenation. ( 28073853 )
2017
29
Role of bispectral index monitoring and burst suppression in prognostication following out-of-hospital cardiac arrest: a systematic review protocol. ( 28946920 )
2017
30
Incidence and survival outcome according to heart rhythm during resuscitation attempt in out-of-hospital cardiac arrest patients with presumed cardiac etiology. ( 28087286 )
2017
31
Serum Calcium and Risk of Sudden Cardiac Arrest in the General Population. ( 28943016 )
2017
32
Targeted Temperature Management Using The "Esophageal Cooling Device" After Cardiac Arrest (The COOL Study): A feasibility and safety study. ( 28951293 )
2017
33
Myoclonus After Cardiac Arrest: Where Do We Go From Here? ( 29225535 )
2017
34
Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial. ( 29058596 )
2017
35
The potential role of auditory evoked potentials to assess prognosis in comatose survivors from cardiac arrest. ( 28942010 )
2017
36
Serum neutrophil gelatinase-associated lipocalin levels predict the neurological outcomes of out-of-hospital cardiac arrest victims. ( 28482803 )
2017
37
Attempts to prevent "tongue swallowing" may well be the main obstacle for successful bystander resuscitation of athletes with cardiac arrest. ( 28939206 )
2017
38
Level of systemic inflammation and endothelial injury is associated with cardiovascular dysfunction and vasopressor support in post cardiac arrest patients. ( 28947390 )
2017
39
Multistate 5-Year Initiative to Improve Care for Out-of-Hospital Cardiac Arrest: Primary Results From the HeartRescue Project. ( 28939711 )
2017
40
The impact of airway strategy on the patient outcome after out-of-hospital cardiac arrest: A propensity score matched analysis. ( 28948850 )
2017
41
Dynamic Changes of Mitochondrial Fusion and Fission in Brain Injury after Cardiac Arrest in Rats. ( 29445732 )
2017
42
Intensive care medicine in 2050: managing cardiac arrest. ( 28070605 )
2017
43
Cardiac arrest caused by rapidly increasing ascites in a patient with TAFRO syndrome: a case report. ( 29123888 )
2017
44
Sudden cardiac arrest as a rare presentation of myxedema coma: case report. ( 29147476 )
2017
45
Gamma-aminobutyric acid-B limbic encephalitis and asystolic cardiac arrest: a case report. ( 29287596 )
2017
46
Survival From Out-of-Hospital Cardiac Arrest: Are We Beginning to See Progress? ( 28939721 )
2017
47
Hydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats. ( 28087437 )
2017
48
Sudden cardiac arrest in patients following surgery for CHD. ( 28084952 )
2017
49
No, No, GO! A call to arms (and hands) for cardiac arrest. ( 28939207 )
2017
50
Repetitive postoperative extubation failure and cardiac arrest due to laryngomalacia after general anesthesia in an elderly patient: a case report. ( 28508288 )
2017

Variations for Cardiac Arrest

ClinVar genetic disease variations for Cardiac Arrest:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 PLN NM_002667.4(PLN): c.116T> G (p.Leu39Ter) single nucleotide variant Pathogenic/Likely pathogenic rs111033560 GRCh37 Chromosome 6, 118880200: 118880200
2 DSP NM_004415.3(DSP): c.2821C> T (p.Arg941Ter) single nucleotide variant Pathogenic/Likely pathogenic rs730880082 GRCh38 Chromosome 6, 7576986: 7576986

Expression for Cardiac Arrest

Search GEO for disease gene expression data for Cardiac Arrest.

Pathways for Cardiac Arrest

Pathways related to Cardiac Arrest according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.43 CALM1 CALM3 KCNQ1 RYR2 SCN5A TNNT2
2 12.3 AVP CALM1 ENO2 S100B SCN5A
3
Show member pathways
12.29 CALM1 CALM3 CYCS RYR2
4
Show member pathways
11.97 ACE MYH7 RYR2 TNNT2
5 11.92 AVP KCNQ1 RYR2 SCN5A
6
Show member pathways
11.9 ALB CALM1 CALM3 KCNQ1 MYH7 RYR2
7 11.56 MYH7 RYR2 TNNT2
8 11.47 ACE CALM1 CALM3
9 11.43 CALM1 CALM3 MYH7
10
Show member pathways
11.43 CALM1 CALM3 KCNQ1 SCN5A
11 11.04 CALM1 CALM3 CYCS
12 11 CASQ2 KCNQ1 RYR2 SCN5A
13 10.62 CALM1 CALM3

GO Terms for Cardiac Arrest

Cellular components related to Cardiac Arrest according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Z disc GO:0030018 9.56 CASQ2 MYH7 RYR2 SCN5A
2 sarcoplasmic reticulum GO:0016529 9.54 CASQ2 RYR2 TRDN
3 sarcoplasmic reticulum membrane GO:0033017 9.5 CASQ2 RYR2 TRDN
4 catalytic complex GO:1902494 9.46 CALM1 CALM3
5 sarcoplasmic reticulum lumen GO:0033018 9.43 CASQ2 TRDN
6 junctional membrane complex GO:0030314 9.4 CASQ2 TRDN
7 junctional sarcoplasmic reticulum membrane GO:0014701 9.33 CASQ2 RYR2 TRDN
8 calcium channel complex GO:0034704 9.26 CALM1 CALM3 CASQ2 RYR2
9 sarcomere GO:0030017 9.02 CALM1 CALM3 MYH7 RYR2 TNNT2

Biological processes related to Cardiac Arrest according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 ion transmembrane transport GO:0034220 9.91 CALM1 CASQ2 KCNQ1 RYR2 SCN5A TRDN
2 muscle contraction GO:0006936 9.81 CALM1 MYH7 TNNT2 TRDN
3 response to calcium ion GO:0051592 9.77 CALM1 CALM3 TNNT2
4 regulation of cardiac conduction GO:1903779 9.75 CASQ2 RYR2 TRDN
5 substantia nigra development GO:0021762 9.71 CALM1 CALM3 CKB
6 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 9.67 CALM1 CALM3 CASQ2 TRDN
7 regulation of cardiac muscle contraction GO:0055117 9.65 CALM1 CALM3 RYR2
8 negative regulation of peptidyl-threonine phosphorylation GO:0010801 9.64 CALM1 CALM3
9 heart contraction GO:0060047 9.63 ACE TRDN
10 positive regulation of phosphoprotein phosphatase activity GO:0032516 9.63 CALM1 CALM3
11 ventricular cardiac muscle cell action potential GO:0086005 9.63 KCNQ1 RYR2 SCN5A
12 cellular response to epinephrine stimulus GO:0071872 9.62 KCNQ1 RYR2
13 regulation of membrane repolarization GO:0060306 9.62 CASQ2 KCNQ1
14 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 9.62 CALM1 CALM3 CASQ2 RYR2
15 atrial cardiac muscle cell action potential GO:0086014 9.61 KCNQ1 SCN5A
16 regulation of cell communication by electrical coupling involved in cardiac conduction GO:1901844 9.61 CALM1 CALM3
17 cellular response to caffeine GO:0071313 9.6 CASQ2 RYR2
18 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 9.58 RYR2 TRDN
19 positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 9.58 CALM1 CALM3 TRDN
20 regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 9.57 KCNQ1 SCN5A
21 positive regulation of cyclic-nucleotide phosphodiesterase activity GO:0051343 9.56 CALM1 CALM3
22 detection of calcium ion GO:0005513 9.56 CALM1 CALM3 CASQ2 RYR2
23 regulation of cell communication by electrical coupling GO:0010649 9.55 CASQ2 TRDN
24 positive regulation of cyclic nucleotide metabolic process GO:0030801 9.52 CALM1 CALM3
25 Purkinje myocyte to ventricular cardiac muscle cell signaling GO:0086029 9.49 CASQ2 RYR2
26 negative regulation of ryanodine-sensitive calcium-release channel activity GO:0060315 9.46 CALM1 CALM3 CASQ2 TRDN
27 cardiac muscle contraction GO:0060048 9.43 CASQ2 KCNQ1 MYH7 RYR2 SCN5A TNNT2
28 regulation of heart rate GO:0002027 9.1 CALM1 CALM3 CASQ2 MYH7 RYR2 SCN5A

Molecular functions related to Cardiac Arrest according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calmodulin binding GO:0005516 9.56 KCNQ1 MYH7 RYR2 SCN5A
2 titin binding GO:0031432 9.4 CALM1 CALM3
3 protein kinase A catalytic subunit binding GO:0034236 9.37 KCNQ1 RYR2
4 adenylate cyclase binding GO:0008179 9.32 CALM1 CALM3
5 protein phosphatase activator activity GO:0072542 9.16 CALM1 CALM3
6 ion channel binding GO:0044325 9.1 CALM1 CALM3 KCNQ1 RYR2 SCN5A TRDN
7 N-terminal myristoylation domain binding GO:0031997 8.96 CALM1 CALM3

Sources for Cardiac Arrest

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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