Aliases & Classifications for Cardiac Arrest

MalaCards integrated aliases for Cardiac Arrest:

Name: Cardiac Arrest 12 29 52 41 14 69
Cardiopulmonary Arrest 12 52 69
Circulatory Arrest 12 69
Heart Arrest 42

Classifications:



Summaries for Cardiac Arrest

MedlinePlus : 41 the heart has an internal electrical system that controls the rhythm of the heartbeat. problems can cause abnormal heart rhythms, called arrhythmias. there are many types of arrhythmia. during an arrhythmia, the heart can beat too fast, too slow, or it can stop beating. sudden cardiac arrest (sca) occurs when the heart develops an arrhythmia that causes it to stop beating. this is different than a heart attack, where the heart usually continues to beat but blood flow to the heart is blocked. there are many possible causes of sca. they include coronary heart disease, physical stress, and some inherited disorders. sometimes there is no known cause for the sca. without medical attention, the person will die within a few minutes. people are less likely to die if they have early defibrillation. defibrillation sends an electric shock to restore the heart rhythm to normal. you should give cardiopulmonary resuscitation (cpr) to a person having sca until defibrillation can be done. if you have had an sca, an implantable cardiac defibrillator (icd) reduces the chance of dying from a second sca. nih: national heart, lung, and blood institute

MalaCards based summary : Cardiac Arrest, also known as cardiopulmonary arrest, is related to jervell and lange-nielsen syndrome and endotheliitis, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Cardiac Arrest is CASQ2 (Calsequestrin 2), and among its related pathways/superpathways are Vascular smooth muscle contraction and Neuroscience. The drugs Clonazepam and Valproic Acid have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and lung, and related phenotypes are Decreased Hepatitis C Virus pseudoparticles (HCVpp and behavior/neurological

Disease Ontology : 12 A congestive heart failure characterized by a sudden stop in effective blood circulation due to the failure of the heart to contract effectively or at all.

Wikipedia : 72 Cardiac arrest is a sudden stop in effective blood flow due to the failure of the heart to contract... more...

Related Diseases for Cardiac Arrest

Diseases related to Cardiac Arrest via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 239)
id Related Disease Score Top Affiliating Genes
1 jervell and lange-nielsen syndrome 31.0 CALM1 CALM3 CASQ2 KCNQ1 RYR2 SCN5A
2 endotheliitis 30.7 CKB ENO2
3 myocardial infarction 30.5 ACE ALB CKB PIK3C2A S100B TNNT2
4 ventricular tachycardia, catecholaminergic polymorphic, 1 30.4 CASQ2 KCNQ1 PIK3C2A RYR2 SCN5A SLC25A20
5 ischemic heart disease 29.8 ACE ALB TNNT2
6 cardiomyopathy 11.1
7 hypoxia 11.1
8 pulmonary edema 11.1
9 anoxia 11.1
10 cerebral hypoxia 11.1
11 wolff-parkinson-white syndrome 11.1
12 eclampsia 11.1
13 infantile histiocytoid cardiomyopathy 11.0
14 ventricular tachycardia, catecholaminergic polymorphic, 3 10.9
15 arrhythmogenic right ventricular dysplasia 2 10.8 CASQ2 RYR2
16 subclavian steal syndrome 10.8 CALM1 CALM3
17 meningitis and encephalitis 10.8 ENO2 S100B
18 benallegue lacete syndrome 10.8 ENO2 S100B
19 myoma 10.8 ENO2 S100B
20 long qt syndrome 15 10.8 CALM1 CALM3
21 epidural spinal canal meningioma 10.8 CALM1 CALM3
22 enteric pattern testicular yolk sac tumor 10.8 ENO2 S100B
23 heterotaxy, visceral, 8, autosomal 10.7 CALM1 CALM3
24 ventricular tachycardia, catecholaminergic polymorphic, 4 10.7
25 cardiac conduction defect 10.7
26 andersen syndrome 10.7
27 sudden cardiac failure, infantile 10.7
28 sudden cardiac failure, alcohol-induced 10.7
29 ventricular tachycardia, catecholaminergic polymorphic, 5, with or without muscle weakness 10.7
30 coronary artery dissection, spontaneous 10.7
31 ventricular tachycardia, catecholaminergic polymorphic, 2 10.7
32 long qt syndrome 1 10.7
33 cyanide poisoning 10.7
34 arrhythmogenic right ventricular cardiomyopathy 10.7
35 myocarditis 10.7
36 pseudohypoaldosteronism, type iic 10.7 CALM1 CALM3
37 motor neuron disease 10.7 ENO2 S100B
38 mononeuritis of lower limb 10.7 CALM1 CALM3
39 atrial standstill, digenic 10.6 SCN5A TNNT2
40 pontiac fever 10.6 CALM1 CALM3
41 regular astigmatism 10.6 CALM1 CALM3
42 brain meningioma 10.5 ALB ENO2 S100B
43 non-congenital cyst of kidney 10.5 ACE ALB
44 cardiac conduction disease with or without dilated cardiomyopathy 10.5 KCNQ1 SCN5A
45 colon leiomyoma 10.5 ACE PIK3C2A
46 dumping syndrome 10.4 CALM1 CALM3
47 hyperaldosteronism, familial, type iii 10.4 KCNQ1 SCN5A
48 deafness, autosomal dominant 2a 10.4 CALM1 CALM3 KCNQ1
49 vascular erectile tumor 10.4 CALM1 KCNQ1 SCN5A
50 plantar fasciitis 10.3 CALM1 CALM3 PIK3C2A

Comorbidity relations with Cardiac Arrest via Phenotypic Disease Network (PDN): (show all 33)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Myocardial Infarction
Aortic Aneurysm Bronchitis
Cardiogenic Shock Chronic Kidney Failure
Chronic Myocardial Ischemia Decubitus Ulcer
Deficiency Anemia Disseminated Intravascular Coagulation
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Generalized Atherosclerosis Heart Conduction Disease
Heart Disease Hypertension, Essential
Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis Intermediate Coronary Syndrome
Ischemic Heart Disease Kidney Disease
Left Ventricular Outflow Tract Obstruction Mitral Valve Disease
Ocular Motor Apraxia Peripheral Vascular Disease
Protein-Energy Malnutrition Pulmonary Hypertension, Familial Primary, 1, with or Without Hht
Respiratory Failure Sinoatrial Node Disease
Third-Degree Atrioventricular Block Tricuspid Valve Disease
Ventricular Fibrillation, Familial, 1

Graphical network of the top 20 diseases related to Cardiac Arrest:



Diseases related to Cardiac Arrest

Symptoms & Phenotypes for Cardiac Arrest

UMLS symptoms related to Cardiac Arrest:


angina pectoris, chest pain, edema

GenomeRNAi Phenotypes related to Cardiac Arrest according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased Hepatitis C Virus pseudoparticles (HCVpp GR00234-A-1 8.8 CALM3 CKB PIK3C2A

MGI Mouse Phenotypes related to Cardiac Arrest:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.73 S100B SCN5A SERPINA6 TRDN ACE AVP
2 renal/urinary system MP:0005367 9.1 ACE ALB AVP PIK3C2A RYR2 SERPINA6

Drugs & Therapeutics for Cardiac Arrest

Drugs for Cardiac Arrest (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 666)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
2
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
3
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 51-43-4 5816
4 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1
5
Ticagrelor Approved Phase 4 274693-27-5 9871419
6
Meperidine Approved Phase 4 57-42-1 4058
7
Ephedrine Approved Phase 4,Phase 2,Phase 3 299-42-3 9294
8
Norepinephrine Approved Phase 4 51-41-2 439260
9
Oxymetazoline Approved Phase 4 1491-59-4 4636
10
Phenylephrine Approved Phase 4 59-42-7 6041
11
Pseudoephedrine Approved Phase 4,Phase 2,Phase 3 90-82-4 7028
12
Ethanol Approved Phase 4,Phase 3,Phase 2 64-17-5 702
13
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2 137-58-6 3676
14
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
15
Midazolam Approved, Illicit Phase 4,Phase 3 59467-70-8 4192
16
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1 2078-54-8 4943
17
Remifentanil Approved Phase 4,Phase 3 132875-61-7 60815
18
Misoprostol Approved Phase 4,Phase 1 59122-46-2 5282381
19
Oxytocin Approved, Vet_approved Phase 4,Phase 2 50-56-6 439302 53477758
20
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
21
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613 2171
22
Ticlopidine Approved Phase 4 55142-85-3 5472
23
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 16590-41-3 5360515
24
Anastrozole Approved, Investigational Phase 4,Phase 2 120511-73-1 2187
25
Tamoxifen Approved Phase 4 10540-29-1 2733526
26
Nifedipine Approved Phase 4 21829-25-4 4485
27
Ritodrine Approved Phase 4 26652-09-5 33572
28
Atropine Approved, Vet_approved Phase 4,Phase 2 5908-99-6, 51-55-8 174174
29
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
30
Simvastatin Approved Phase 4,Phase 3 79902-63-9 54454
31
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
32
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
33
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
34
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
35
Norgestimate Approved Phase 4 35189-28-7 6540478
36
Ofloxacin Approved Phase 4 82419-36-1 4583
37
Fluvastatin Approved Phase 4 93957-54-1 1548972
38
Candesartan Approved Phase 4 139481-59-7 2541
39
Salicylic acid Approved, Vet_approved Phase 4 69-72-7 338
40
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
41
Thrombin Approved Phase 4,Phase 3
42
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
43
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
44
Letrozole Approved, Investigational Phase 4,Phase 2,Phase 1 112809-51-5 3902
45
Progesterone Approved, Vet_approved Phase 4,Phase 2,Phase 3 57-83-0 5994
46
Pioglitazone Approved, Investigational Phase 4,Phase 2,Phase 3 111025-46-8 4829
47
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
48
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
49
Haloperidol Approved Phase 4 52-86-8 3559
50
Olanzapine Approved, Investigational Phase 4 132539-06-1 4585

Interventional clinical trials:

(show top 50) (show all 1159)

id Name Status NCT ID Phase Drugs
1 The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild Hypothermia Unknown status NCT01083784 Phase 4 Use of prophylactic anticonvulsants (valproate, clonazepam);Control group
2 Sodium Bicarbonate in Cardiopulmonary Resuscitation Unknown status NCT01377337 Phase 4 sodium bicarbonate
3 Effects and Plasma Concentration of Ticagrelor, After Crushed and Non-crushed Intake, After Acute Coronary Syndrome Unknown status NCT02341729 Phase 4 ticagrelor
4 Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women Unknown status NCT01555671 Phase 4 Placebo;Meperidine
5 Early Feeding Following Ligation of Acute Bleeding Varices Unknown status NCT01287702 Phase 4
6 Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome Unknown status NCT00815100 Phase 4 Ivabradine;Placebo
7 Out-of Hospital Resuscitation Study Unknown status NCT00196248 Phase 4
8 IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction Unknown status NCT00157768 Phase 4
9 Arrhythmia Restart Prevention and RatE STabilization in Atrial Fibrillation Unknown status NCT00224341 Phase 4
10 A Pilot Trial of Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients Unknown status NCT02203630 Phase 4 Phenylephrine;Norepinephrine
11 Vasopressin and Epinephrine Versus Epinephrine Alone in Cardiac Arrest Completed NCT00127907 Phase 4 epinephrine (1 mg/1 mL);arginine-vasopressin (40 UI/2 mL)
12 Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest Completed NCT02899507 Phase 4 Amoxicillin-Clavulanic acid
13 Clinical and Economical Interest of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA Study) Completed NCT00392639 Phase 4
14 Comparing Therapeutic Hypothermia Using External and Internal Cooling for Post-Cardiac Arrest Patients Completed NCT00827957 Phase 4
15 Continuous Chest Compressions vs AHA Standard CPR of 30:2 Completed NCT01372748 Phase 4
16 Trial of Different Hypothermia Temperatures in Patients Recovered From Out-of-hospital Cardiac Arrest Completed NCT01155622 Phase 4
17 COOL-Trial: Outcome With Invasive and Non-invasive Cooling After Cardiac Arrest Completed NCT00843297 Phase 4
18 Antiplatelet Therapy After Cardiac Arrest Completed NCT02224274 Phase 4 Clopidogrel;Ticagrelor
19 Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest Completed NCT01369732 Phase 4 recombinant human erythropoietin;saline
20 Cardiopulmonary Resuscitation Witnessing by a Relative Completed NCT01009606 Phase 4
21 Quick ICD Study: Is Extensive Electrophysiological Testing Before, During and After ICD-Implantation Still Necessary ? Completed NCT00180362 Phase 4
22 Transthoracic Incremental Monophasic Versus Biphasic by Emergency Responders (TIMBER) Completed NCT00101881 Phase 4
23 Beating Versus Arrested Heart for Mitral Valve Replacement Completed NCT01641614 Phase 4
24 A Study of VIVITROL in the Prevention of Re-arrest and Re-incarceration Completed NCT01453374 Phase 4 VIVITROL 380mg
25 Neuron Specific Enolase (NSE) as Outcome Parameter of Cooling Therapy After Survived Sudden Cardiac Death Completed NCT01102153 Phase 4
26 Arimidex Observational: Reason for and Effect of Change From Tamoxifen Completed NCT00246961 Phase 4
27 Multicenter Automatic Defibrillator Implantation Trial - Reduce Inappropriate Therapy Completed NCT00947310 Phase 4
28 Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion Completed NCT00454428 Phase 4
29 Comparative Study Between Nifedipine and Ritodrine as Maintenance Tocolytic Therapy in Preterm Labor Completed NCT03040752 Phase 4 Nifedipine 20 Mg;Ritodrine Oral Tablet
30 ISSUE3: International Study on Syncope of Uncertain Etiology 3 Completed NCT00359203 Phase 4
31 The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions Completed NCT02953886 Phase 4
32 Atropine for Prevention of Dysrhythmias Caused by Percutaneous Ethanol Instillation for Hepatoma Therapy Completed NCT00575523 Phase 4 Atropine;Placebo
33 The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial Completed NCT00430989 Phase 4 Nitrous Oxide;Nitrous Oxide
34 Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHD Completed NCT00159835 Phase 4 atorvastatin;simvastatin
35 Avelox for Treatment of Elderly Patients With Community Acquired Pneumonia Completed NCT00665327 Phase 4 Avelox (Moxifloxacin, BAY12-8039);Levofloxacin
36 Study of Mechanisms of Anovulation in Polycystic Ovary Syndrome Completed NCT00492882 Phase 4 usual administration of exogenous recombinant FSH
37 Out-of-Hospital Intubation With Metal Single Use Laryngoscope Blades Completed NCT00644722 Phase 4
38 Fluvastatin in the Therapy of Acute Coronary Syndrome Completed NCT00171275 Phase 4 Fluvastatin
39 Heart Outcomes Prevention Evaluation-3 Completed NCT00468923 Phase 4 Candesartan/HCT;Rosuvastatin
40 Preventive and Therapeutic Proximal Sealants Completed NCT02338180 Phase 4
41 Lipitor In The Prevention Of Stroke, For Patients Who Have Had A Previous Stroke Completed NCT00147602 Phase 4 atorvastatin
42 CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events Completed NCT00327418 Phase 4 Atorvastatin
43 Clinical Trial to Evaluate the Use of an Adsorption Membrane (OXIRIS®) During Cardiopulmonary Bypass Surgery Completed NCT02398019 Phase 4
44 Combination Therapy of Low Doses of rFVIIa and FEIBA for Severe Hemophilia A Patients With an Inhibitor to Factor VIII Completed NCT00284193 Phase 4 rFVIIa-FEIBA therapy for hemophilia A inhibitors;FEIBA- Activated Prothrombin Complexes
45 Addition of Dexmedetomidine to Ropivacaine-induced Supraclavicular Block (ADRIB Trial) Completed NCT02630290 Phase 4 Ropivacaine;Ropivacaine + Dexmedetomidine
46 Aromatase Inhibitor Effects on Ovarian Function During the Follicular and Early Luteal Phase in Women Completed NCT01046578 Phase 4 Letrozole;Letrozole;Letrozole;Letrozole;Letrozole;Letrozole
47 Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism Completed NCT00837616 Phase 4 17 B estradiol orally;17 B estradiol
48 Molecular Mechanisms of Type 2 Diabetes Mellitus Completed NCT00816218 Phase 4 Pioglitazone
49 A Study to Determine the Degree of Additional Reduction in CV Risk in Lowering LDL Below Minimum Target Levels Completed NCT00327691 Phase 4 Atorvastatin
50 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated Completed NCT01157351 Phase 4 paliperidone;risperidone;haloperidole;perphenazine;aripiprazole;quetiapine;paliperidone palmitate;olanzapine

Search NIH Clinical Center for Cardiac Arrest

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: heart arrest

Genetic Tests for Cardiac Arrest

Genetic tests related to Cardiac Arrest:

id Genetic test Affiliating Genes
1 Cardiac Arrest 29

Anatomical Context for Cardiac Arrest

MalaCards organs/tissues related to Cardiac Arrest:

39
Heart, Brain, Lung, Testes, Kidney, Bone, Prostate

Publications for Cardiac Arrest

Articles related to Cardiac Arrest:

(show top 50) (show all 448)
id Title Authors Year
1
Quick epinephrine administration induces favorable neurological outcomes in out-of-hospital cardiac arrest patients. ( 28087097 )
2017
2
Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest. ( 28934276 )
2017
3
The potential role of auditory evoked potentials to assess prognosis in comatose survivors from cardiac arrest. ( 28942010 )
2017
4
Global Registry of Acute Coronary Events risk score predicts mortality and neurological outcome in out-of hospital cardiac arrest. ( 28082161 )
2017
5
Endothelial function impairment in STEMI patients with out-of-hospital cardiac arrest under therapeutic hypothermia treatment. ( 28087172 )
2017
6
Coronary angiography findings in cardiac arrest patients with non-diagnostic post-resuscitation electrocardiogram: A comparison of shockable and non-shockable initial rhythms. ( 28932359 )
2017
7
Level of systemic inflammation and endothelial injury is associated with cardiovascular dysfunction and vasopressor support in post cardiac arrest patients. ( 28947390 )
2017
8
The impact of airway strategy on the patient outcome after out-of-hospital cardiac arrest: A propensity score matched analysis. ( 28948850 )
2017
9
Sudden cardiac arrest in patients following surgery for CHD. ( 28084952 )
2017
10
Incidence and survival outcome according to heart rhythm during resuscitation attempt in out-of-hospital cardiac arrest patients with presumed cardiac etiology. ( 28087286 )
2017
11
Hydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats. ( 28087437 )
2017
12
Pathophysiology and the Monitoring Methods for Cardiac Arrest Associated Brain Injury. ( 28085069 )
2017
13
Sudden Cardiac Arrest While Eating a Hot Dog: A Rare Presentation of Brugada Syndrome in a Child. ( 28877999 )
2017
14
Glycocalyx degradation leads to blood-brain barrier dysfunction and brain edema after asphyxia cardiac arrest in rats. ( 28825336 )
2017
15
Repetitive postoperative extubation failure and cardiac arrest due to laryngomalacia after general anesthesia in an elderly patient: a case report. ( 28508288 )
2017
16
Serum Calcium: A Sudden Cardiac Arrest Risk Factor. ( 28943015 )
2017
17
Successful early application of extracorporeal membrane oxygenation to support cardiopulmonary resuscitation for a patient suffering from severe malignant hyperthermia and cardiac arrest: a case report. ( 28580087 )
2017
18
Cardiac Arrest: Obstetric CPR/ACLS. ( 28079556 )
2017
19
The impact of cardiac arrest on the long-term wellbeing and caregiver burden of family caregivers: a prospective cohort study. ( 28068794 )
2017
20
Attempts to prevent "tongue swallowing" may well be the main obstacle for successful bystander resuscitation of athletes with cardiac arrest. ( 28939206 )
2017
21
Responsive monitoring of mitochondrial redox states in heart muscle predicts impending cardiac arrest. ( 28931652 )
2017
22
Pulmonary emboli cardiac arrest with CPR complication: Liver laceration and massive abdominal bleed, a case report. ( 28092783 )
2017
23
No, No, GO! A call to arms (and hands) for cardiac arrest. ( 28939207 )
2017
24
Survival From Out-of-Hospital Cardiac Arrest: Are We Beginning to See Progress? ( 28939721 )
2017
25
Clinical profile of patients with cardiac arrest induced by aortic disease. ( 28830716 )
2017
26
Rosuvastatin improves myocardial and neurological outcomes after asphyxial cardiac arrest and cardiopulmonary resuscitation in rats. ( 28076830 )
2017
27
Temporal Pattern and Prognostic Significance of Hypokalemia in Patients Undergoing Targeted Temperature Management Following Cardiac Arrest. ( 28803654 )
2017
28
Systemic impact on secondary brain aggravation due to ischemia/reperfusion injury in post-cardiac arrest syndrome: a prospective observational study using high-mobility group box 1 protein. ( 28950909 )
2017
29
The use of therapeutic magnesium for neuroprotection during global cerebral ischemia associated with cardiac arrest and cardiac surgery in adults: a systematic review. ( 28085730 )
2017
30
Targeted Temperature Management Using The "Esophageal Cooling Device" After Cardiac Arrest (The COOL Study): A feasibility and safety study. ( 28951293 )
2017
31
Case Report of Cardiac Arrest After Succinylcholine in a Child With Muscle-Eye-Brain Disease. ( 28604469 )
2017
32
Prognostic significance of spontaneous shockable rhythm conversion in adult out-of-hospital cardiac arrest patients with initial non-shockable heart rhythms: a systematic review and meta-analysis. ( 28943123 )
2017
33
Validation of a Dispatch Protocol with Continuous Quality Control for Cardiac Arrest: A Before-and-After Study at a City Fire Department-Based Dispatch Center. ( 28943036 )
2017
34
Serum Calcium and Risk of Sudden Cardiac Arrest in the General Population. ( 28943016 )
2017
35
Intensive care medicine in 2050: managing cardiac arrest. ( 28070605 )
2017
36
Competence in the use of supraglottic airways by Australian surf lifesavers for cardiac arrest ventilation in a manikin. ( 28078762 )
2017
37
Cardiac arrest due to ventricular fibrillation in a 23-year-old woman with broken heart syndrome. ( 28802178 )
2017
38
Experience with integrating pharmacist documenters on cardiac arrest teams to improve quality. ( 28941721 )
2017
39
How to develop a clinic for sudden cardiac arrest survivors and families of non-survivors. ( 28084954 )
2017
40
Delayed-onset Reversible Cortical Blindness after Resuscitation from Cardiac Arrest. ( 28936091 )
2017
41
Identification of novel biomarkers for prediction of neurological prognosis following cardiac arrest. ( 28147324 )
2017
42
Resuscitation of prolonged cardiac arrest from massive pulmonary embolism by extracorporeal membrane oxygenation. ( 28073853 )
2017
43
Clinical documentation of in-hospital cardiac arrest in a large national health system. ( 28087287 )
2017
44
Role of bispectral index monitoring and burst suppression in prognostication following out-of-hospital cardiac arrest: a systematic review protocol. ( 28946920 )
2017
45
End-tidal carbon dioxide and defibrillation success in out-of-hospital cardiac arrest. ( 28942011 )
2017
46
Multistate 5-Year Initiative to Improve Care for Out-of-Hospital Cardiac Arrest: Primary Results From the HeartRescue Project. ( 28939711 )
2017
47
Extracorporeal membrane oxygenation for refractory cardiac arrest. ( 28074817 )
2017
48
Serial neuropsychological assessment of an adolescent girl after suffering a sudden out-of-hospital-cardiac-arrest following recreational inhalant use. ( 27216834 )
2016
49
Reperfusion injury protection during Basic Life Support improves circulation and survival outcomes in a porcine model of prolonged cardiac arrest. ( 27211835 )
2016
50
Risk factors and outcomes of in-hospital cardiac arrest following pediatric heart operations of varying complexity. ( 27185218 )
2016

Variations for Cardiac Arrest

ClinVar genetic disease variations for Cardiac Arrest:

6
id Gene Variation Type Significance SNP ID Assembly Location
1 PLN NM_002667.4(PLN): c.116T> G (p.Leu39Ter) single nucleotide variant Pathogenic/Likely pathogenic rs111033560 GRCh37 Chromosome 6, 118880200: 118880200
2 DSP NM_004415.3(DSP): c.2821C> T (p.Arg941Ter) single nucleotide variant Pathogenic/Likely pathogenic rs730880082 GRCh38 Chromosome 6, 7576986: 7576986

Expression for Cardiac Arrest

Search GEO for disease gene expression data for Cardiac Arrest.

Pathways for Cardiac Arrest

Pathways related to Cardiac Arrest according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.61 CALM1 CALM3 KCNQ1 RYR2 SCN5A TNNT2
2 12.23 AVP CALM1 ENO2 S100B SCN5A
3
Show member pathways
12.23 CALM1 CALM3 KCNQ1 RYR2 SCN5A TNNT2
4
Show member pathways
12.16 ALB CALM1 CALM3 RYR2
5 11.92 AVP KCNQ1 RYR2 SCN5A
6 11.42 ACE CALM1 CALM3
7
Show member pathways
11.33 CALM1 CALM3 KCNQ1 SCN5A
8 10.98 CALM1 CALM3 CYCS
9 10.67 CASQ2 KCNQ1 RYR2 SCN5A
10 10.59 CALM1 CALM3

GO Terms for Cardiac Arrest

Cellular components related to Cardiac Arrest according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 sarcoplasmic reticulum GO:0016529 9.54 CASQ2 RYR2 TRDN
2 sarcomere GO:0030017 9.46 CALM1 CALM3 RYR2 TNNT2
3 sarcoplasmic reticulum lumen GO:0033018 9.43 CASQ2 TRDN
4 sarcoplasmic reticulum membrane GO:0033017 9.43 CASQ2 RYR2 TRDN
5 junctional membrane complex GO:0030314 9.4 CASQ2 TRDN
6 myelin sheath GO:0043209 9.32 ALB CKB
7 junctional sarcoplasmic reticulum membrane GO:0014701 9.13 CASQ2 RYR2 TRDN
8 calcium channel complex GO:0034704 8.92 CALM1 CALM3 CASQ2 RYR2

Biological processes related to Cardiac Arrest according to GeneCards Suite gene sharing:

(show all 27)
id Name GO ID Score Top Affiliating Genes
1 ion transmembrane transport GO:0034220 9.89 CASQ2 KCNQ1 RYR2 SCN5A TRDN
2 response to calcium ion GO:0051592 9.75 CALM1 CALM3 TNNT2
3 regulation of cardiac conduction GO:1903779 9.73 CASQ2 RYR2 TRDN
4 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 9.67 CALM1 CALM3 CASQ2 TRDN
5 negative regulation of peptidyl-threonine phosphorylation GO:0010801 9.63 CALM1 CALM3
6 heart contraction GO:0060047 9.63 ACE TRDN
7 regulation of cardiac muscle contraction GO:0055117 9.63 CALM1 CALM3 RYR2
8 positive regulation of phosphoprotein phosphatase activity GO:0032516 9.62 CALM1 CALM3
9 cellular response to epinephrine stimulus GO:0071872 9.62 KCNQ1 RYR2
10 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 9.62 CALM1 CALM3 CASQ2 RYR2
11 regulation of membrane repolarization GO:0060306 9.61 CASQ2 KCNQ1
12 atrial cardiac muscle cell action potential GO:0086014 9.61 KCNQ1 SCN5A
13 ventricular cardiac muscle cell action potential GO:0086005 9.61 KCNQ1 RYR2 SCN5A
14 regulation of cell communication by electrical coupling involved in cardiac conduction GO:1901844 9.59 CALM1 CALM3
15 cellular response to caffeine GO:0071313 9.58 CASQ2 RYR2
16 positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 9.58 CALM1 CALM3 TRDN
17 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 9.57 RYR2 TRDN
18 detection of calcium ion GO:0005513 9.56 CALM1 CALM3 CASQ2 RYR2
19 regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 9.55 KCNQ1 SCN5A
20 cardiac muscle contraction GO:0060048 9.55 CASQ2 KCNQ1 RYR2 SCN5A TNNT2
21 positive regulation of cyclic-nucleotide phosphodiesterase activity GO:0051343 9.54 CALM1 CALM3
22 regulation of cell communication by electrical coupling GO:0010649 9.52 CASQ2 TRDN
23 positive regulation of cyclic nucleotide metabolic process GO:0030801 9.51 CALM1 CALM3
24 Purkinje myocyte to ventricular cardiac muscle cell signaling GO:0086029 9.48 CASQ2 RYR2
25 positive regulation of systemic arterial blood pressure GO:0003084 9.3 AVP
26 negative regulation of ryanodine-sensitive calcium-release channel activity GO:0060315 9.26 CALM1 CALM3 CASQ2 TRDN
27 regulation of heart rate GO:0002027 9.02 CALM1 CALM3 CASQ2 RYR2 SCN5A

Molecular functions related to Cardiac Arrest according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 titin binding GO:0031432 9.26 CALM1 CALM3
2 protein kinase A catalytic subunit binding GO:0034236 9.16 KCNQ1 RYR2
3 ion channel binding GO:0044325 9.1 CALM1 CALM3 KCNQ1 RYR2 SCN5A TRDN
4 protein phosphatase activator activity GO:0072542 8.96 CALM1 CALM3

Sources for Cardiac Arrest

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
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44 MGI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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