Aliases & Classifications for Cardiac Rupture

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Sources:
41NIH Rare Diseases, 43Novoseek, 60UMLS
See all sources

Cardiac Rupture, Aliases & Descriptions:

Name: Cardiac Rupture 41 43
 
Myocardial Rupture 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Summaries for Cardiac Rupture

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MalaCards based summary: Cardiac Rupture, also known as myocardial rupture, is related to myocardial infarction and pericardial effusion. An important gene associated with Cardiac Rupture is CHKB (choline kinase beta), and among its related pathways are Selenium Pathway and Cell adhesion ECM remodeling. The compounds thallium and enalaprilat have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and brain, and related mouse phenotypes are cellular and behavior/neurological.

Related Diseases for Cardiac Rupture

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Diseases related to Cardiac Rupture via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 54)
idRelated DiseaseScoreTop Affiliating Genes
1myocardial infarction31.1CHKB, PLAT, CRP, NPPB
2pericardial effusion30.7CHKB
3acute myocardial infarction30.5MMP9, CHKB, PLAT, CRP, NPPB
4ischemia29.9CHKB, PLAT, NPPB
5coronary artery disease29.9CHKB, PLAT, CRP, NPPB
6neuroleptic malignant syndrome10.5CHKB
7cholesteatoma10.3MMP9
8aneurysm10.3
9endophthalmitis10.3PLAT, PRF1
10cardiac tamponade10.3
11hemopericardium10.3
12middle ear cholesteatoma10.3CHKB, MMP9
13limb-girdle muscular dystrophy10.2CHKB, FLNC
14bacteriuria10.2CRP
15aortic aneurysm10.2CRP
16angiosarcoma10.2
17artery disease10.2
18hemorrhage, intracerebral10.2PLAT, NPPB
19cardiogenic shock10.2PLAT, NPPB
20pulmonary embolism10.2NPPB, PLAT
21synovitis10.2CRP
22skin disease10.2PRF1, MMP9
23muscular dystrophy10.1FLNC, CHKB
24ventricular septal defect10.1
25atrial fibrillation10.1NPPB, PLAT, CHKB
26myocarditis10.1CHKB, PRF1, NPPB
27hyperhomocysteinemia10.0CRP, PLAT
28nutritional deficiency disease10.0CRP, CHKB
29carotid stenosis10.0CRP, MMP9
30noonan syndrome 110.0NPPB, CHKB, FLNC
31pulmonary disease, chronic obstructive10.0MMP9, CRP
32congestive heart failure10.0NPPB, CHKB
33systemic lupus erythematosus10.0
34congenital disorder of glycosylation, type ia10.0
35lung cancer10.0
36factor xiii deficiency10.0
37hypertrophic cardiomyopathy10.0
38cerebritis10.0
39lupus erythematosus10.0
40mediastinitis10.0
41pericarditis10.0
42myopathy9.9FLNC, CHKB, CRP
43vascular disease9.9MMP9, PLAT, CRP
44amyloidosis9.9NPPB, CRP
45periodontal disease9.9CRP, MMP9
46meningitis9.9MMP9, PRF1, CRP
47melanoma9.8FLNC, MMP9, CHKB, PRF1
48stroke, ischemic9.8NPPB, CRP, PLAT
49kawasaki disease9.8NPPB, CRP, MMP9
50congenital heart disease9.8MMP9, CRP, NPPB

Graphical network of the top 20 diseases related to Cardiac Rupture:



Diseases related to cardiac rupture

Symptoms for Cardiac Rupture

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Drugs & Therapeutics for Cardiac Rupture

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Drug clinical trials:

Search ClinicalTrials for Cardiac Rupture

Search NIH Clinical Center for Cardiac Rupture

Genetic Tests for Cardiac Rupture

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Anatomical Context for Cardiac Rupture

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MalaCards organs/tissues related to Cardiac Rupture:

31
Heart, Testes, Brain, Liver, Lung

Animal Models for Cardiac Rupture or affiliated genes

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MGI Mouse Phenotypes related to Cardiac Rupture:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053848.0TRIM54, PLAT, PRF1, MMP9, PMM2
2MP:00053867.6FLNC, MMP9, CHKB, PRF1, PLAT, TRIM54
3MP:00053697.5FLNC, MMP9, CHKB, PLAT, NPPB, TRIM54
4MP:00107687.2PMM2, FLNC, MMP9, PRF1, PLAT, TRIM54
5MP:00053856.8TRIM54, PMM2, FLNC, MMP9, PLAT, CRP

Publications for Cardiac Rupture

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Articles related to Cardiac Rupture:

(show top 50)    (show all 303)
idTitleAuthorsYear
1
Magnetic resonance imaging-based management of silent cardiac rupture. (25483899)
2015
2
Thymosin-I^4 prevents cardiac rupture and improves cardiac function in mice with myocardial infarction. (25015963)
2014
3
Trends in the clinical and pathological characteristics of cardiac rupture in patients with acute myocardial infarction over 35 years. (25332178)
2014
4
Cardiac rupture. (22305150)
2013
5
Extracorporeal life support in a severe blunt chest trauma with cardiac rupture. (24829813)
2013
6
Sutureless repair for postinfarction cardiac rupture: a simple approach with a tissue-adhering patch. (22999512)
2013
7
Blunt cardiac rupture in the setting of previous sternotomy. (22579894)
2012
8
Acute myocardial infarction and swinging heart: not always a cardiac rupture--haemopericardium due to infiltrative lung cancer. (22645189)
2012
9
Administration of intrapericardial tissue adhesive after cardiac rupture and cardiac tamponade. (19201492)
2011
10
Survival of blunt cardiac rupture after asystolic arrest: a case report. (19359944)
2009
11
Cardiac rupture or pericardial effusion? (17692412)
2008
12
Five cases of blunt traumatic cardiac rupture: success and failure in surgical management. (17554994)
2007
13
Targeted deletion of p53 prevents cardiac rupture after myocardial infarction in mice. (16533502)
2006
14
Cardiac rupture after minor blunt chest injury as a result of occult recent myocardial infarction. (16129541)
2005
15
Usefulness of delayed enhancement magnetic resonance imaging for detecting cardiac rupture caused by small myocardial infarction in a case of cardiac tamponade. (16308508)
2005
16
Effect of reperfusion therapy on cardiac rupture after myocardial infarction in Japanese. (15118282)
2004
17
Three-dimensional echocardiography of post-myocardial infarction cardiac rupture. (15053793)
2004
18
Cardiac rupture in acute myocardial infarction: a reassessment. (11953501)
2002
19
Endoventricular circular patch plasty with aortic valve replacement for post-infarction cardiac rupture complicated with aortic valve stenosis: case report. (12381096)
2002
20
Renin-angiotensin system and cardiac rupture after myocardial infarction. (12390941)
2002
21
Primary coronary angioplasty in acute myocardial infarction: is it possible to prevent postinfarction cardiac rupture? (10929740)
2000
22
Blunt cardiac rupture: the utility of emergency department ultrasound. (10355395)
1999
23
Diagnosis and treatment of blunt cardiac rupture. (9090319)
1997
24
Cardiac rupture with dobutamine stress echocardiography. (9440077)
1997
25
Cardiac rupture due to blunt trauma. (9225900)
1997
26
C-reactive protein as a predictor of cardiac rupture after acute myocardial infarction. (8615301)
1996
27
Treatment of acute cardiac rupture by autologous pericardial patch without infarctectomy. (8054736)
1994
28
Clinico-pathological study of the role of infarct expansion in patients with cardiac rupture following acute myocardial infarction. (7966995)
1994
29
Survival after postinfarction cardiac rupture in severe aortic valve stenosis. (8174576)
1994
30
Cardiac rupture, a clinically predictable complication of acute myocardial infarction: report of 70 cases with clinicopathologic correlations. (8354804)
1993
31
Angiosarcoma of the heart causing cardiac rupture: a rare cause of hemopericardium. (8431074)
1993
32
Intramyocardial dissecting hematoma: an unusual form of subacute cardiac rupture. (8286867)
1993
33
A partial defect in technetium-99m pyrophosphate image suggesting cardiac rupture following acute myocardial infarction. (1533369)
1992
34
The use of echocardiography in the emergency management of nonpenetrating traumatic cardiac rupture. (1952316)
1991
35
Cardiac rupture due to severe fatty infiltration in the right ventricular wall. (1919483)
1991
36
Cardiac rupture secondary to blunt trauma: a rapidly diagnosable entity with two-dimensional echocardiography. (1854076)
1991
37
Primary angiosarcoma of the heart causing cardiac rupture. (2741790)
1989
38
Sutureless repair of postinfarction cardiac rupture. (2980052)
1988
39
Pseudoaneurysm--a treatable form of cardiac rupture. (3202017)
1988
40
Cardiac rupture secondary to isolated midcircumflex artery obstruction. (3480457)
1987
41
Cardiac rupture, abdominal aneurysmal rupture and dissecting aortic rupture: a preventive trio. (3962881)
1986
42
Association of eosinophils with cardiac rupture. (3997134)
1985
43
Surgical repair of acute postinfarction cardiac rupture. (3979071)
1985
44
Acute cardiac rupture and tamponade: angiographic appearance. (3969907)
1985
45
Vasopressors and cardiac rupture. (7223670)
1981
46
Anatomic, clinical, and therapeutic features of acute cardiac rupture. Successful surgical management fourteen hours after myocardial infarction. (661371)
1978
47
Postinfarction cardiac rupture. (5285998)
1971
48
Sudden death due to cardiac rupture in myocardial ischemia and infarction. Causes, mechanism, and possible prevention. (5252737)
1969
49
FACTORS IN CARDIAC RUPTURE. (14055888)
1963
50
Spontaneous Cardiac Rupture. (20322160)
1941

Variations for Cardiac Rupture

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Expression for genes affiliated with Cardiac Rupture

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Search GEO for disease gene expression data for Cardiac Rupture.

Pathways for genes affiliated with Cardiac Rupture

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Pathways related to Cardiac Rupture according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
thioredoxin pathway36
9.5CRP, PLAT
2
Show member pathways
Metalloproteases in connective tissue degradation
9.3PLAT, MMP9
39.3MMP9, PLAT
49.3PLAT, MMP9
59.3PLAT, MMP9

Compounds for genes affiliated with Cardiac Rupture

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Compounds related to Cardiac Rupture according to GeneCards Suite gene sharing:

(show top 50)    (show all 92)
idCompoundScoreTop Affiliating Genes
1thallium4310.0NPPB, CHKB
2enalaprilat439.8PLAT, NPPB
3dobutamine43 28 49 1212.7NPPB, PLAT, CHKB
4quinapril43 49 1211.7PLAT, CRP
5ptca439.7NPPB, PLAT, CHKB
6ceftriaxone43 1210.7CRP, PLAT
7spec-t439.7NPPB, PLAT, CHKB
8trapidil439.7PLAT, MMP9
9abciximab43 1210.6CHKB, PLAT, CRP
10omapatrilat439.6MMP9, PLAT
11clopidogrel43 49 24 1212.6CHKB, PLAT, CRP
12thyroxine43 2410.5NPPB, PLAT, CHKB
13tirofiban43 1210.4NPPB, CRP, PLAT
14perindopril43 49 1211.4PLAT, CRP, NPPB
15p005439.4NPPB, CRP, PLAT
16uric acid43 2410.4NPPB, CRP, CHKB
17pravastatin43 49 28 24 1213.4NPPB, CRP, CHKB
18losartan43 49 28 1212.4NPPB, CRP, PLAT
19ramipril43 1210.3CRP, NPPB
20valsartan43 59 28 1212.3NPPB, CRP
21p003439.3PLAT, CRP, NPPB
22prednisolone43 28 1211.3CHKB, CRP, NPPB
23homocysteine43 2410.3NPPB, CRP, PLAT
24phosphorylcholine43 2410.2CRP, CHKB
25aprotinin43 1210.2MMP9, PLAT, NPPB
26nacl439.2NPPB, PRF1, CHKB
27gabexate mesilate439.1MMP9, PLAT, CRP
28nitroglycerin43 1210.1CHKB, PLAT, CRP, NPPB
29prostacyclin439.1NPPB, CRP, PLAT
30aspirin43 49 28 2412.1CHKB, PLAT, CRP, NPPB
31alpha tocopherol439.1CRP, CHKB, MMP9
32fosinopril43 1210.0NPPB, CRP, MMP9
338-isoprostane438.9NPPB, CRP, MMP9
34pioglitazone28 43 49 1211.9MMP9, CRP, NPPB
35cholesterol43 28 24 1211.9CHKB, PRF1, PLAT, CRP
36cyclosporin a43 28 5910.8MMP9, CHKB, PLAT, NPPB
37fluvastatin43 49 28 1211.8MMP9, CHKB, PLAT, CRP
38simvastatin43 49 59 28 24 1213.8CRP, PLAT, CHKB, MMP9
39rosiglitazone28 43 49 24 1212.8NPPB, CRP, MMP9
40fibrinogen438.8MMP9, CHKB, PLAT, CRP
41cyclophosphamide43 49 1210.7NPPB, CRP, MMP9
42aspartate438.7MMP9, CHKB, PLAT, CRP
43p002438.6NPPB, CRP, PLAT, MMP9
44norepinephrine43 24 1210.6MMP9, CHKB, CRP, NPPB
45cycloheximide438.6MMP9, PRF1, PLAT, CRP
46lactate438.5MMP9, CHKB, CRP, NPPB
47testosterone43 59 24 1211.3MMP9, CHKB, CRP, NPPB
48atorvastatin43 49 28 24 1212.3NPPB, CRP, PLAT, CHKB, MMP9
49creatinine438.3MMP9, CHKB, PLAT, CRP, NPPB
50calcium43 49 24 1210.7FLNC, MMP9, CHKB, PRF1, CRP, NPPB

GO Terms for genes affiliated with Cardiac Rupture

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Cellular components related to Cardiac Rupture according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.2NPPB, CRP, PLAT, MMP9
2extracellular regionGO:00055767.5NPPB, CRP, PLAT, PRF1, MMP9

Products for genes affiliated with Cardiac Rupture

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Sources for Cardiac Rupture

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet