Aliases & Classifications for Cardiac Sarcoidosis

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Cardiac Sarcoidosis, Aliases & Descriptions:

Name: Cardiac Sarcoidosis 9 60


External Ids:

Disease Ontology9 DOID:13405
SNOMED-CT55 75403004
NCIt38 C35589

Summaries for Cardiac Sarcoidosis

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MalaCards based summary: Cardiac Sarcoidosis is related to dilated cardiomyopathy and peritonitis. An important gene associated with Cardiac Sarcoidosis is PSMB8 (proteasome (prosome, macropain) subunit, beta type, 8), and among its related pathways are TRAF Pathway and IL12-mediated signaling events. The compounds lipoteichoic acid and sulfasalazine have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and brain, and related mouse phenotypes are liver/biliary system and tumorigenesis.

Related Diseases for Cardiac Sarcoidosis

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Diseases related to Cardiac Sarcoidosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 122)
idRelated DiseaseScoreTop Affiliating Genes
1dilated cardiomyopathy30.4NPPB, ACE, HLA-DQB1
2peritonitis30.1IL1B, IL15, TNF
3pulmonary tuberculosis30.1IL12B, IFNG, HLA-DQB1
4coronary artery disease30.0LTA, NPPB, ACE
5tuberculosis29.4HLA-DQB1, TNF, IFNG, IL12B, IL1B
6atrioventricular block10.5
7intervertebral disc disease10.5IL1B
8pulpitis10.4IL1A
9aneurysm10.4
10periodontal disease10.4TNF
11celiac disease10.4IL15, HLA-DQB1
12arrhythmogenic right ventricular cardiomyopathy10.4
13myocarditis10.4
14pleurisy10.3IL1B
15oligohydramnios10.3ACE
16mixed connective tissue disease10.3S100A9, S100A8
17giant cell myocarditis10.3
18encephalitis10.3IL12B, IL1B
19leishmaniasis10.3IFNG
20asthma10.3IL12B, TNF
21tonsillitis10.3IL1A, LTA
22middle ear cholesteatoma10.3IL1A, S100A8
23duodenal ulcer10.3S100A8, LTA
24periodontitis10.3IL1B, IL1A
25shigellosis10.3LTA, IL1B
26skin disease10.3IL1B, IL1A
27hypertrophic cardiomyopathy10.2
28dermatomyositis10.2IL1A, S100A9, S100A8
29bacterial vaginosis10.2IL1B, IL1A
30schizophrenia10.2HLA-DQB1, TAP1, LTA
31spondylarthropathy10.2TNF, S100A9, S100A8
32spondyloarthropathy 110.2TAP2, TAP1, TNF
33sjogren's syndrome10.2S100A9, S100A8, TAP1, TAP2
34lepromatous leprosy10.2LTA, IFNG
35blau syndrome10.2TNF, IL1B
36aids dementia complex10.2TNF, IL1B
37hypertensive heart disease10.2NPPB, ACE
38visceral leishmaniasis10.2IFNG, LTA
39idiopathic edema10.2ACE, NPPB
40alcoholic hepatitis10.1TNF, IL1A
41gingival overgrowth10.1IL1B, IL1A
42familial mediterranean fever, ar10.1TNF, IL1B
43gout10.1S100A9, IL1B
44chorioamnionitis10.1TNF, IL1B
45polymyositis10.1IL15, IL1A, S100A9, S100A8
46tropical spastic paraparesis10.1IFNG, IL15
47acute respiratory distress syndrome10.1TNF, IL1B, LTA
48alopecia areata10.1IFNG, IL1A
49hashimoto thyroiditis10.1IL12B, IFNG, PSMB8
50bronchitis10.1S100A9, S100A8

Graphical network of the top 20 diseases related to Cardiac Sarcoidosis:



Diseases related to cardiac sarcoidosis

Symptoms for Cardiac Sarcoidosis

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Drugs & Therapeutics for Cardiac Sarcoidosis

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Drug clinical trials:

Search ClinicalTrials for Cardiac Sarcoidosis

Search NIH Clinical Center for Cardiac Sarcoidosis

Genetic Tests for Cardiac Sarcoidosis

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Anatomical Context for Cardiac Sarcoidosis

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MalaCards organs/tissues related to Cardiac Sarcoidosis:

31
Heart, Bone, Brain, Myeloid, Monocytes, T cells, Lymph node

Animal Models for Cardiac Sarcoidosis or affiliated genes

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MGI Mouse Phenotypes related to Cardiac Sarcoidosis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.7LTA, ACE, IFNG, TNF, HLA-DQB1
2MP:00020067.9TNF, PSMB8, IFNG, ACE, IL12B, IL1B
3MP:00053857.1HLA-DQB1, TNF, IFNG, ACE, IL15, IL1B
4MP:00053766.9HLA-DQB1, TNF, IFNG, ACE, IL12B, IL1B
5MP:00053975.6LTA, HLA-DMA, HLA-DQB1, TNF, PSMB8, IFNG
6MP:00053875.5ACE, IFNG, PSMB8, TNF, HLA-DQB1, HLA-DMA
7MP:00107685.4ACE, IFNG, TNF, HLA-DQB1, HLA-DMA, IL15

Publications for Cardiac Sarcoidosis

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Articles related to Cardiac Sarcoidosis:

(show top 50)    (show all 378)
idTitleAuthorsYear
1
Isolated cardiac sarcoidosis: Clinical characteristics, diagnosis and treatment. (25577749)
2015
2
Circulating CD14(++)CD16(+) Monocyte Subsets as a Surrogate Marker of the Therapeutic Effect of Corticosteroid Therapy in Patients With Cardiac Sarcoidosis. (25833081)
2015
3
Effect of Corticosteroid Therapy on Long-Term Clinical Outcome and Left Ventricular Function in Patients With Cardiac Sarcoidosis. (25877828)
2015
4
Advanced imaging of cardiac sarcoidosis. (25702313)
2015
5
Cardiac sarcoidosis. (24969032)
2014
6
Isolated right ventricular cardiac sarcoidosis demonstrated by (18)FDG positron emission tomography. (24429936)
2014
7
Quantifying myocardial inflammation using F18-fluorodeoxyglucose positron emission tomography in cardiac sarcoidosis. (24942609)
2014
8
Visual findings of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with cardiac sarcoidosis. (25224185)
2014
9
Cardiac Sarcoidosis: Electrophysiological Outcomes on Long-Term Follow-Up and the Role of the Implantable Cardioverter-Defibrillator. (24433308)
2013
10
Efficacy of heparin loading during an 18F-FDG PET/CT examination to search for cardiac sarcoidosis activity. (23334129)
2013
11
The invisible made visible: multi-modality imaging in the evaluation of cardiac sarcoidosis. (23391582)
2013
12
Complete somatostatin-induced insulin suppression combined with heparin loading does not significantly suppress myocardial 18F-FDG uptake in patients with suspected cardiac sarcoidosis. (24132814)
2013
13
Malignant ventricular arrhythmia as the first manifestation of cardiac sarcoidosis. (24104986)
2013
14
Inactive cardiac sarcoidosis with characteristic findings on cardiac MRI. (24177462)
2013
15
Response to steroid therapy in cardiac sarcoidosis: insights from myocardial strain. (21990278)
2012
16
Cardiac sarcoidosis mimicking arrhythmogenic right ventricular dysplasia with high defibrillation threshold requiring subcutaneous shocking coil implantation. (21982156)
2012
17
Delayed enhancement on cardiac magnetic resonance imaging is a poor prognostic factor in patients with cardiac sarcoidosis. (22944174)
2012
18
Sudden death due to pulmonary embolism in a patient with cardiac sarcoidosis. (22706660)
2012
19
Diagnosis and monitoring of cardiac sarcoidosis with delayed-enhanced MRI and 18F-FDG PET-CT. (22466988)
2012
20
Cardiac sarcoidosis presenting with complete atrioventricular block and sustained monomorphic ventricular tachycardia. (22977456)
2012
21
Arrhythmias in cardiac sarcoidosis: diagnosis and treatment. (22186166)
2012
22
Diagnosis of cardiac sarcoidosis through mismatched defects seen on N-13 NH3/F-18 FDG cardiac PET. (22064101)
2011
23
Cardiac sarcoidosis: a comprehensive review. (22291785)
2011
24
Cardiac sarcoidosis: recurrent disease in a heart transplant patient following pulmonary tuberculosis infection. (20847976)
2010
25
Diagnosing cardiac sarcoidosis clinically without tissue confirmation. (19633746)
2009
26
Dual left ventricular restorations in a patient with cardiac sarcoidosis. (19380011)
2009
27
Multiple involvements of cardiac sarcoidosis in both left and right ventricles and papillary muscles detected by delayed-enhanced magnetic resonance imaging. (17689728)
2008
28
Successful treatment of cardiac sarcoidosis with infliximab. (18671332)
2008
29
Exercise intolerance and multiple conduction abnormalities as first manifestation of cardiac sarcoidosis. (18791500)
2008
30
Cardiac sarcoidosis: a case report. (19044177)
2008
31
An unappetizing dog bone: cardiac sarcoidosis presenting with heart block and unusual left ventricular bulging. (18065753)
2008
32
Complementary appearance of glucose and lipid metabolism in cardiac sarcoidosis. (16872698)
2007
33
Reversible exercise-induced advanced atrioventricular block due to cardiac sarcoidosis. (17199004)
2007
34
Usefulness of late gadolinium enhancement combined with MRI and 67-Ga scintigraphy in the diagnosis of cardiac sarcoidosis and disease activity evaluation. (16868855)
2007
35
Enhanced expression of myeloid-related protein complex (MRP8/14) in macrophages and multinucleated giant cells in granulomas of patients with active cardiac sarcoidosis. (17895549)
2007
36
Cardiac sarcoidosis underlies idiopathic dilated cardiomyopathy: importance of mediastinal lymphadenopathy in differential diagnosis. (18037750)
2007
37
The intricacies of cardiac sarcoidosis: a case report involving the coronary arteries and a review of the literature. (16844554)
2006
38
Images in cardiology. Biventricular involvement in cardiac sarcoidosis. (16230435)
2005
39
Relationship between basal thinning of the interventricular septum and atrioventricular block in patients with cardiac sarcoidosis. (15881282)
2005
40
Cardiac sarcoidosis: there is no instant replay. (16002904)
2005
41
Diagnostic Value of PET in Cardiac Sarcoidosis. (15534072)
2004
42
Cardiac sarcoidosis: two cases with autopsy findings. (16196153)
2004
43
Detection of denervated but viable myocardium in cardiac sarcoidosis with I-123 MIBG and Tl-201 SPECT imaging. (11577764)
2001
44
Discrepancy between inducibility of ventricular tachycardia and activity of cardiac sarcoidosis. Requirement of defibrillator implantation for the inactive stage of cardiac sarcoidosis. (11518112)
2001
45
HLA-DQB1*0601 is primarily associated with the susceptibility to cardiac sarcoidosis. (10958356)
2000
46
Incidence of cardiac sarcoidosis in Japanese patients with high-degree atrioventricular block. (9327691)
1997
47
Sudden death due to cardiac sarcoidosis in a case of suspected homicide. (8217872)
1993
48
Cardiac sarcoidosis. (2355460)
1990
49
Two dimensional echocardiography and left ventriculography in cardiac sarcoidosis. (2631668)
1989
50
MYOCARDIAL DEGENERATION IN CARDIAC SARCOIDOSIS: HISTOCHEMICAL AND ELECTRON MICROSCOPIC STUDIES. (14256691)
1965

Variations for Cardiac Sarcoidosis

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Expression for genes affiliated with Cardiac Sarcoidosis

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Search GEO for disease gene expression data for Cardiac Sarcoidosis.

Pathways for genes affiliated with Cardiac Sarcoidosis

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Pathways related to Cardiac Sarcoidosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5IL12B, TNF, LTA
2
Show member pathways
Immune response IL 12 induced IFN gamma production58
9.5IL1B, IFNG, IL12B
3
Show member pathways
9.5IL12B, IFNG, IL1B
49.5TAP1, IL1B, IFNG
59.4IL1B, IL12B, TNF
6
Show member pathways
Immune response IL 22 signaling pathway58
G protein signaling N RAS regulation pathway58
9.4HLA-DMA, HLA-DQB1, IL12B
79.4IL1B, TNF, LTA
8
Show member pathways
9.4IL1A, IFNG, IL1B
99.4IFNG, IL1A, IL1B
109.4TNF, IL1A, IL1B
119.4TNF, IL1B, IL1A
12
Show member pathways
9.4IFNG, LTA, TNF
139.3TNF, IFNG, IL1B
14
Show member pathways
thioredoxin pathway36
9.3TNF, IL1B, IFNG
159.2HLA-DMA, HLA-DQB1, TAP1, TAP2
169.1IL1B, IL1A, IL12B, TNF
17
Show member pathways
9.1LTA, TNF, IL1A, IL1B
18
Show member pathways
9.1IL1A, IL1B, LTA, TNF
19
Show member pathways
9.1TNF, IL15, IFNG
20
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
9.0IL1B, IL12B, IFNG, TNF
219.0TNF, IFNG, IL1B, IL12B
229.0IL1B, TNF, IFNG, IL12B
239.0TNF, IL1B, IL12B, IFNG
249.0TNF, IL1A, IFNG, IL1B
25
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
9.0IFNG, TNF, IL1A, IL1B
269.0IL1A, IFNG, TNF, IL1B
279.0TNF, IL1B, IL1A, IFNG
28
Show member pathways
Immune response MIF in innate immunity response58
9.0TNF, IL1B, IFNG, IL1A
29
Show member pathways
8.9HLA-DMA, TAP1, HLA-DQB1, PSMB8, TAP2
30
Show member pathways
8.9IFNG, IL1B, PSMB8, IL1A, HLA-DQB1
318.9TNF, IL15, IL1B, LTA
32
Show member pathways
Proteasome Degradation36
Immune response Antigen presentation by MHC class I58
8.9PSMB8, IFNG, TNF, TAP1, TAP2
33
Show member pathways
IL27-mediated signaling events36
8.8LTA, TNF, IFNG, IL12B, IL1B
34
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
8.7IL1B, IFNG, TNF, IL1A, LTA
35
Show member pathways
8.7TNF, IL1A, IL1B, IFNG, LTA
36
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
8.7ACE, IL1B, IL12B, TNF, IFNG
378.5HLA-DMA, HLA-DQB1, LTA, IL15, TNF
38
Show member pathways
8.4LTA, IL15, IL12B, IL1A, IL1B, TNF
39
Show member pathways
8.4IL1A, IL1B, LTA, TNF, IL12B, IL15
40
Show member pathways
8.4LTA, IL1A, IL1B, IL12B, IL15, TNF
418.2TNF, IL15, IL12B, IL1A, IFNG, IL1B
42
Show member pathways
8.2IFNG, HLA-DQB1, IL1B, TNF, IL1A, HLA-DMA
43
Show member pathways
8.0IL1B, LTA, IL1A, IL12B, IL15, TNF
448.0LTA, IL1A, IL1B, IL12B, IL15, TNF
45
Show member pathways
7.9TNF, HLA-DMA, HLA-DQB1, IL1A, IL1B, IL12B
467.9TNF, HLA-DMA, HLA-DQB1, IFNG, IL1A, IL12B
47
Show member pathways
7.7LTA, IL1A, IL1B, IL12B, IL15, IFNG
487.6TNF, HLA-DMA, IL1A, IL1B, IL15, IFNG
49
Show member pathways
6.6TNF, HLA-DMA, HLA-DQB1, IFNG, IL15, LTA
50
Show member pathways
6.6IL15, HLA-DMA, HLA-DQB1, TNF, IFNG, IL12B

Compounds for genes affiliated with Cardiac Sarcoidosis

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Compounds related to Cardiac Sarcoidosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 141)
idCompoundScoreTop Affiliating Genes
1lipoteichoic acid439.5LTA, TNF, IL12B, IL1B
2sulfasalazine28 43 49 1212.5IL1A, IL12B, IL1B, TNF
3imiquimod43 59 28 1212.5IL1A, IL12B, IFNG, TNF
4gold sodium thiomalate439.4IL1B, IFNG, IL1A, TNF
5polymyxin b439.3IL1B, TNF, IFNG, IL1A
6tenidap43 2810.3IL1B, TNF, IL1A
7okt3439.2LTA, IL15, IFNG, TNF
8ivig439.1LTA, IL1B, IL1A, TNF, IFNG
9neopterin439.1LTA, IL1B, IFNG, TNF, IL1A
10l-nmma439.1TNF, NPPB, IL1B, IFNG
11herbimycin a43 5910.0IL1A, IL1B, IFNG, LTA, TNF
12il-12438.9IL1B, IL12B, IFNG, TNF, IL15
13poly(i-c)438.9IL1B, IL15, IL12B, IFNG, TNF
14peptidoglycan43 289.9TNF, IL15, IL12B, IL1B
15etanercept43 49 1210.9TNF, IL15, LTA, IL1B, IFNG
16infliximab43 49 1210.9LTA, IFNG, IL1B, IL15, TNF
17prostacyclin438.9NPPB, IL1B, ACE, TNF, IL1A
18gm-csf43 289.9IL1A, TNF, IL15, IFNG, IL1B
19p005438.9S100A8, LTA, NPPB, IL15
20ccl343 289.8IL1B, IL15, IFNG, IL1A, TNF
21ionomycin438.8IL15, LTA, IL1A, IFNG, TNF
22git 27598.8S100A8, IL1A, IL1B, S100A9
234-ipp598.8S100A8, S100A9, IL1A, IL1B
24sb 20358043 599.8IL12B, IL1A, NPPB, TNF, IFNG, IL1B
25hydrocortisone43 2 59 1211.8IL15, IL1B, IFNG, IL1A, TNF
26indomethacin43 28 59 1211.8IL1B, NPPB, IL1A, IFNG, TNF, LTA
27as 10143 599.8S100A8, IL1B, IL1A, S100A9
28fmlp438.7TNF, IL1B, S100A9, LTA, IL1A
29actinomycin d438.7IL1A, IFNG, TNF, IL1B, LTA, NPPB
30polyinosinic-polycytidylic acid438.7IL12B, IL1B, IL1A, IL15, TNF, IFNG
31pentoxifylline43 129.6IFNG, TNF, IL12B, LTA, NPPB, IL1A
32il 10438.4IL1B, IL12B, TNF, IFNG, IL15, IL1A
33pirfenidone43 599.4IFNG, IL1A, S100A9, S100A8, IL1B
34monosodium urate438.4IL1B, S100A8, S100A9
35cyclosporin a43 28 5910.4IL15, TNF, IFNG, IL1A, NPPB, LTA
36cycloheximide438.3IL1A, IL12B, TNF, IFNG, LTA, IL1B
37rantes438.3IL1B, IL1A, IL15, S100A8, IFNG, IL12B
38thymidine43 249.1NPPB, IL15, IL1A, IL1B, IFNG, TNF
39pge2438.1TNF, IFNG, IL15, IL12B, IL1A, NPPB
40vegf438.1IFNG, IL15, TNF, IL1B, LTA, IL1A
41thalidomide43 49 59 1210.9IL1B, IL1A, IFNG, S100A8, S100A9, TNF
42histamine43 28 249.9IL15, TNF, S100A8, IL1B, NPPB, IFNG
43arachidonic acid43 28 24 1210.9IL1A, LTA, S100A8, S100A9, TNF, IL1B
44oligonucleotide437.8HLA-DQB1, HLA-DMA, IL15, S100A8, TAP1, TAP2
45calcitriol43 59 24 1210.7TNF, IFNG, LTA, S100A8, IL1A, IL1B
46endotoxin437.5IL12B, IL1B, IL1A, S100A9, S100A8, LTA
47retinoic acid43 248.1S100A8, IL15, IFNG, TNF, S100A9, IL1B
48lipid437.0LTA, NPPB, S100A9, IL12B, IL15, ACE
49dexamethasone43 49 28 129.9TNF, NPPB, S100A9, S100A8, IL1A, IL1B
50nitric oxide43 24 128.3IFNG, ACE, IL15, IL12B, IL1A, S100A9

GO Terms for genes affiliated with Cardiac Sarcoidosis

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Cellular components related to Cardiac Sarcoidosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1TAP complexGO:00428259.9TAP1, TAP2
2MHC class II protein complexGO:00426139.4HLA-DQB1, HLA-DMA
3external side of plasma membraneGO:00098979.2ACE, IFNG, TNF
4extracellular regionGO:00055766.3TNF, IFNG, ACE, IL15, IL1B, IL1A
5extracellular spaceGO:00056155.9LTA, TNF, IFNG, ACE, IL15, IL12B

Biological processes related to Cardiac Sarcoidosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 71)
idNameGO IDScoreTop Affiliating Genes
1cytosol to ER transportGO:004696710.3TAP1, TAP2
2oligopeptide transmembrane transportGO:003567210.3TAP1, TAP2
3antigen processing and presentation of endogenous peptide antigen via MHC class IGO:001988510.3TAP1, TAP2
4intracellular transport of viral protein in host cellGO:001906010.3TAP1, TAP2
5fever generationGO:000166010.2IL1B, IL1A
6positive regulation of granulocyte macrophage colony-stimulating factor productionGO:003272510.2IL12B, IL1B
7positive regulation of chronic inflammatory response to antigenic stimulusGO:000287610.2TNF, LTA
8positive regulation of T cell mediated cytotoxicityGO:000191610.1TAP2, TAP1, IL12B
9sequestering of triglycerideGO:003073010.0TNF, IL1B
10positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292510.0TNF, LTA
11positive regulation of tissue remodelingGO:003410510.0IL15, IL12B
12peptide transportGO:001583310.0TAP1, TAP2
13positive regulation of natural killer cell proliferationGO:003281910.0IL15, IL12B
14positive regulation of heterotypic cell-cell adhesionGO:003411610.0TNF, IL1B
15positive regulation of fever generationGO:003162210.0TNF, IL1B
16positive regulation of vitamin D biosynthetic processGO:006055710.0TNF, IFNG
17ectopic germ cell programmed cell deathGO:003523410.0IL1B, IL1A
18antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentGO:000247910.0TAP2, TAP1, PSMB8
19positive regulation of smooth muscle cell apoptotic processGO:00343939.9IFNG, IL12B
20positive regulation of interleukin-6 biosynthetic processGO:00454109.9IFNG, IL1B
21positive regulation of NF-kappaB import into nucleusGO:00423469.9TNF, IL12B, IL1B
22positive regulation of osteoclast differentiationGO:00456729.8TNF, IFNG, IL12B
23positive regulation of mitosisGO:00458409.8IL1A, IL1B, TNF
24negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:020012409.8IL1A, IL1B, TNF
25antigen processing and presentation of exogenous peptide antigen via MHC class IGO:00425909.7TAP2, TAP1, PSMB8
26negative regulation of smooth muscle cell proliferationGO:00486629.7IL12B, IL15, IFNG
27humoral immune responseGO:00069599.7LTA, IFNG, TNF
28positive regulation of calcidiol 1-monooxygenase activityGO:00605599.7TNF, IFNG, IL1B
29positive regulation of chemokine biosynthetic processGO:00450809.7IL1B, IFNG, TNF
30positive regulation of membrane protein ectodomain proteolysisGO:00510449.7TNF, IFNG, IL1B
31positive regulation of nitric oxide biosynthetic processGO:00454299.7TNF, IFNG, IL1B
32positive regulation of interferon-gamma productionGO:00327299.6LTA, IL1B, IL12B, TNF
33positive regulation of immune responseGO:00507789.6HLA-DMA, IL15
34negative regulation of growth of symbiont in hostGO:00441309.6LTA, IL12B, IFNG, TNF
35negative regulation of interleukin-17 productionGO:00327009.5IL12B, IFNG
36neutrophil aggregationGO:00704889.4S100A9, S100A8
37chemokine productionGO:00326029.4S100A9, S100A8
38positive regulation of T cell proliferationGO:00421029.4IL1B, IL12B, IL15, IFNG
39sequestering of zinc ionGO:00321199.4S100A9, S100A8
40cytokine-mediated signaling pathwayGO:00192219.3HLA-DQB1, PSMB8, IFNG, IL1B, IL1A
41leukocyte migration involved in inflammatory responseGO:00025239.3S100A9, S100A8
42regulation of insulin secretionGO:00507969.2TNF, IFNG, IL1B
43cell-cell signalingGO:00072679.1IL15, IL1B, S100A9, LTA
44immune responseGO:00069559.0IL1A, IL1B, IL15, HLA-DQB1
45apoptotic processGO:00069158.9TNF, PSMB8, IFNG, IL1B, IL1A, LTA
46activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069198.8TNF, S100A9, S100A8
47neutrophil chemotaxisGO:00305938.7IFNG, IL1B, S100A9, S100A8
48positive regulation of inflammatory responseGO:00507298.7IL15, IL12B, S100A9, S100A8
49positive regulation of NF-kappaB transcription factor activityGO:00510928.6TNF, IL1B, S100A9, S100A8
50inflammatory responseGO:00069547.9TNF, IL15, IL1B, IL1A, S100A9, S100A8

Molecular functions related to Cardiac Sarcoidosis according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1tapasin bindingGO:004698010.2TAP1, TAP2
2MHC class Ib protein bindingGO:002302910.2TAP1, TAP2
3peptide transporter activityGO:001519710.2TAP1, TAP2
4oligopeptide-transporting ATPase activityGO:001542110.2TAP1, TAP2
5TAP2 bindingGO:004697910.1TAP1, TAP2
6TAP1 bindingGO:004697810.1TAP1, TAP2
7peptide antigen bindingGO:004260510.0TAP2, TAP1
8MHC class I protein bindingGO:00422889.9TAP2, TAP1
9interleukin-1 receptor bindingGO:00051499.8IL1B, IL1A
10tumor necrosis factor receptor bindingGO:00051649.5LTA, TNF
11Toll-like receptor 4 bindingGO:00356629.3S100A9, S100A8
12arachidonic acid bindingGO:00505449.2S100A9, S100A8
13RAGE receptor bindingGO:00507869.1S100A8, S100A9
14cytokine activityGO:00051258.3LTA, TNF, IFNG, IL15, IL12B, IL1B
15protein bindingGO:00055156.5IL15, ACE, PSMB8, TNF, IL12B, IL1A

Products for genes affiliated with Cardiac Sarcoidosis

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Sources for Cardiac Sarcoidosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet