MCID: CRD137
MIFTS: 42

Cardiogenic Shock malady

Rare diseases, Cardiovascular diseases categories

Aliases & Classifications for Cardiogenic Shock

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Sources:
47Orphanet, 60UMLS, 26ICD10 via Orphanet, 25ICD10
See all sources

Cardiogenic Shock, Aliases & Descriptions:

Name: Cardiogenic Shock 47
 
Shock, Cardiogenic 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Cardiovascular diseases


Characteristics (Orphanet epidemiological data):

47
cardiogenic shock:
Prevalence: 1-5/10000 (Europe)


External Ids:

Orphanet47 97292
ICD10 via Orphanet26 R57.0
ICD1025 R57.0

Summaries for Cardiogenic Shock

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Wikipedia:63 Cardiogenic shock is a life-threatening medical condition resulting from an inadequate circulation of... more...

MalaCards based summary: Cardiogenic Shock, also known as shock, cardiogenic, is related to acute myocardial infarction and pulmonary embolism. An important gene associated with Cardiogenic Shock is HFE2 (hemochromatosis type 2 (juvenile)), and among its related pathways are Amoebiasis and TRAF Pathway. The drugs inamrinone and digitoxin and the compounds gold sodium thiomalate and cuprophan have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and kidney.

Related Diseases for Cardiogenic Shock

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Diseases related to Cardiogenic Shock via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1acute myocardial infarction31.6NPPB, CD14
2pulmonary embolism30.6NPPB, APOH
3lupus erythematosus30.5IFNA2, APOH
4atherosclerosis30.0CD14, IL1R1, APOH
5myocardial infarction11.2
6myocarditis10.7
7pheochromocytoma10.6
8left ventricular outflow tract obstruction10.6
9coronary artery disease10.5
10inferior myocardial infarction10.5
11acute myocarditis10.5
12artery disease10.5
13endocarditis10.4
14degos disease10.4APOH
15retinal vasculitis10.4APOH
16hepatitis10.4
17myxedema10.4
18atrioventricular block10.4
19ventricular septal defect10.4
20systemic lupus erythematosus10.3
21hemochromatosis10.3
22dilated cardiomyopathy10.3
23antiphospholipid syndrome10.3
24hypertrophic cardiomyopathy10.3
25myocardial stunning10.3
26churg-strauss syndrome10.3
27beriberi10.3
28cerebritis10.3
29hypothyroidism10.3
30influenza10.3
31pneumonia10.3
32catastrophic antiphospholipid syndrome10.3
33polyarteritis nodosa10.3IFNA2
34heart valve disease10.1NPPB, APOH
35rheumatic disease10.1IL1R1, APOH
36periodontitis10.1IL1R1, CD14
37asthma10.1
38kawasaki disease10.1
39anorexia nervosa10.1
40pulmonary hypertension10.1
41myasthenia gravis10.1
42thalassemia10.1
43hepatitis c10.1
44intrahepatic cholestasis10.1
45renovascular hypertension10.1
46peripheral artery disease10.1
47cardiac tamponade10.1
48peripartum cardiomyopathy10.1
49coronary thrombosis10.1
50constrictive pericarditis10.1

Graphical network of the top 20 diseases related to Cardiogenic Shock:



Diseases related to cardiogenic shock

Symptoms for Cardiogenic Shock

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Drugs & Therapeutics for Cardiogenic Shock

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Drug clinical trials:

Search ClinicalTrials for Cardiogenic Shock

Search NIH Clinical Center for Cardiogenic Shock

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Cardiogenic Shock

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Anatomical Context for Cardiogenic Shock

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MalaCards organs/tissues related to Cardiogenic Shock:

31
Heart, Liver, Kidney, Monocytes, Lung, Breast, Prostate, Endothelial, Tongue, Pituitary

Animal Models for Cardiogenic Shock or affiliated genes

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Publications for Cardiogenic Shock

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Articles related to Cardiogenic Shock:

(show top 50)    (show all 578)
idTitleAuthorsYear
1
Acute inferior myocardial infarction with right ventricular infarction is more prone to develop cardiogenic shock. (25725666)
2015
2
Early glucose variability in cardiogenic shock following acute myocardial infarction: a pilot study. (25810479)
2015
3
Wretched excess: stool-softener abuse and cardiogenic shock. (23968901)
2013
4
Levosimendan for the treatment of subarachnoid hemorrhage-related cardiogenic shock. (23673402)
2013
5
A new approach for early onset cardiogenic shock in acute colchicine overdose: place of early extracorporeal life support (ECLS)? (23612758)
2013
6
BET 3: evaluation of intra-aortic balloon support in cardiogenic shock. (24232009)
2013
7
Cardiogenic shock. (24188221)
2013
8
Post myocardial infarction cardiogenic shock: a review of current therapies. (21747126)
2013
9
Cardiovascular outcomes using intra-aortic balloon pump in high-risk acute myocardial infarction with or without cardiogenic shock: a meta-analysis. (21335478)
2012
10
Balloon pump support for cardiogenic shock after AMI. (23099571)
2012
11
Intra-aortic balloon support for MI and cardiogenic shock--time to change the guidelines? (22965109)
2012
12
Usefulness of cardiac biomarkers to predict cardiac recovery in patients on extracorporeal membrane oxygenation support for refractory cardiogenic shock. (22386227)
2012
13
What is the evidence for IABP in STEMI with and without cardiogenic shock? (22569335)
2012
14
Repairing a "broken heart" with hormone replacement therapy: case report of cardiogenic shock due to undiagnosed pituitary insufficiency. (22138080)
2012
15
Intra-aortic balloon counterpulsation in the treatment of infarction-related cardiogenic shock--review of the current evidence. (22607158)
2012
16
Cardiogenic shock and awe. (22378244)
2012
17
Role of receptor for advanced glycation end products in cardiogenic shock. (22430238)
2012
18
Intraaortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock: design and rationale of the Intraaortic Balloon Pump in Cardiogenic Shock II (IABP-SHOCK II) trial. (22709745)
2012
19
Emergency surgery for native mitral valve endocarditis: the impact of septic and cardiogenic shock. (22342063)
2012
20
Aorto-right atrial fistula secondary to infective endocarditis presenting with cardiogenic shock. (21045716)
2012
21
Successful use of a percutaneous miniaturized extracorporeal life support system as a bridge and assistance to left ventricular assist device implantation in a patient with severe refractory cardiogenic shock. (21859786)
2012
22
Churg-Strauss syndrome presenting with acute myocarditis and cardiogenic shock. (21963398)
2012
23
Cardiogenic shock in an elderly man caused by left main coronary artery occlusion with spontaneous dissection of right coronary artery. (21152670)
2011
24
Impella assisted transradial coronary intervention in patients with acute coronary syndromes and cardiogenic shock: case series. (21523889)
2011
25
The ability to achieve complete revascularization is associated with improved in-hospital survival in cardiogenic shock due to myocardial infarction: Manitoba cardiogenic SHOCK Registry investigators. (21547996)
2011
26
Defining refractory myocardial infarction-associated cardiogenic shock: an ongoing elusive challenge. (21248538)
2011
27
Evaluation and management of shock States: hypovolemic, distributive, and cardiogenic shock. (21507874)
2011
28
Hypothermia in cardiogenic shock reduces systemic t-PA release. (21190125)
2011
29
Cardiogenic shock due to dynamic left ventricular outflow tract obstruction in acute myocardial infarction. (21452037)
2011
30
Posterior ventricular septal defect in presence of cardiogenic shock: early implantation of the impella recover LP 5.0 as a bridge to surgery. (21423467)
2011
31
Mechanical versus pharmacologic support for cardiogenic shock. (20049971)
2010
32
Immediate cardiac arrest and subsequent development of cardiogenic shock caused by lightning strike. (20065746)
2010
33
Early extracorporeal membrane oxygenator-assisted primary percutaneous coronary intervention improved 30-day clinical outcomes in patients with ST-segment elevation myocardial infarction complicated with profound cardiogenic shock. (20543669)
2010
34
Intraoperative pulseless electrical activity and acute cardiogenic shock after administration of phenylephrine, epinephrine, and ketamine. (21603379)
2010
35
Acute kidney injury in ST-segment elevation acute myocardial infarction complicated by cardiogenic shock at admission. (19789449)
2010
36
Case series: CT scan in cardiac arrest and imminent cardiogenic shock. (20607032)
2010
37
Reversible cardiogenic shock in hypertrophic cardiomyopathy after alcohol septal ablation. (21074128)
2010
38
Combined use of Impella device and intra-aortic balloon pump to improve survival in a patient in profound cardiogenic shock post cardiac arrest. (19521993)
2009
39
Catastrophic antiphospholipid syndrome complicated by cardiogenic shock - a case report]. (19650000)
2009
40
Percutaneous left ventricular assist devices during cardiogenic shock and high-risk percutaneous coronary interventions. (19709497)
2009
41
The use of extracorporeal membrane oxygenation in patients with therapy refractory cardiogenic shock as a bridge to implantable left ventricular assist device and perioperative right heart support. (19894089)
2009
42
Clinical significance of post-procedural TIMI flow in patients with cardiogenic shock undergoing primary percutaneous coronary intervention. (19463399)
2009
43
Coronary artery bypass graft surgery provides better survival in patients with acute coronary syndrome or ST-segment elevation myocardial infarction experiencing cardiogenic shock after percutaneous coronary intervention: a propensity score analysis. (19660378)
2009
44
Contemporary management of cardiogenic shock: age is opportunity. (19463418)
2009
45
Cardiogenic shock without flow-limiting angiographic coronary artery disease: (from the Should We Emergently Revascularize Occluded Coronary Arteries for Cardiogenic Shock Trial and Registry). (19576316)
2009
46
Usefulness of intra-aortic balloon pump counterpulsation in patients with cardiogenic shock from acute myocardial infarction. (19616662)
2009
47
Images in cardiology: Acute adrenal insufficiency complicated by cardiogenic shock. (15772180)
2005
48
Comparative study of artificial circulation for the liver after cardiogenic shock: pulsatile or nonpulsatile?]. (9884562)
1998
49
Role of right ventricular infarction in cardiogenic shock associated with inferior myocardial infarction. (534590)
1979
50
Contribution to the enzymic diagnosis of acute myocarditis, myocardial infarction and cardiogenic shock. (5384064)
1969

Variations for Cardiogenic Shock

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Expression for genes affiliated with Cardiogenic Shock

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Search GEO for disease gene expression data for Cardiogenic Shock.

Pathways for genes affiliated with Cardiogenic Shock

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Pathways related to Cardiogenic Shock according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4CD14, IL1R1
2
Show member pathways
9.4CD14, IL1R1
3
Show member pathways
Immune response MIF in innate immunity response58
9.4CD14, IL1R1
49.4CD14, IL1R1
59.4CD14, IL1R1
6
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
9.4IL1R1, CD14
7
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways58
Immune response IL 1 signaling pathway58
8.6CD14, IL1R1, IFNA2
8
Show member pathways
8.6IFNA2, IL1R1, CD14

Compounds for genes affiliated with Cardiogenic Shock

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Compounds related to Cardiogenic Shock according to GeneCards Suite gene sharing:

(show top 50)    (show all 78)
idCompoundScoreTop Affiliating Genes
1gold sodium thiomalate439.8CD14, IL1R1
2cuprophan439.6CD14, IL1R1
3ptca439.6NPPB, APOH
4polysulfone439.4CD14, IL1R1
5lipoteichoic acid439.4APOH, IL1R1, CD14
6endotoxin439.3IL1R1, CD14, APOH
7uric acid43 2410.3APOH, IL1R1, NPPB
8allopurinol43 49 1211.3IFNA2, NPPB
9p002439.2CD14, NPPB, APOH
10nitrate439.2IL1R1, CD14, NPPB
11p00001439.2NPPB, CD14
12pentoxifylline43 1210.2CD14, NPPB, IL1R1
13aspirin43 49 28 2412.2NPPB, IL1R1, APOH
14fibrinogen439.1CD14, IL1R1, APOH
15hydroxychloroquine43 1210.1IL1R1, APOH, IFNA2
16etanercept43 49 1211.1APOH, IL1R1, IFNA2
178-isoprostane439.1APOH, NPPB
18infliximab43 49 1211.1APOH, IFNA2, IL1R1
19rituximab43 49 1211.1IFNA2, IL1R1, APOH
20cellulose439.1IL1R1, CD14, IFNA2
21vitamin d439.0CD14, NPPB, IL1R1
22gold439.0APOH, IFNA2, IL1R1
23neopterin439.0IL1R1, IFNA2, CD14
24norepinephrine43 24 1210.9CD14, NPPB, IL1R1
25methionine438.9CD14, IL1R1, IFNA2
26cyclosporin a43 28 5910.8IL1R1, NPPB, CD14
27epinephrine43 24 1210.8NPPB, IL1R1, IFNA2
28p003438.8CD14, NPPB, IL1R1, APOH
29homocysteine43 249.8IL1R1, NPPB, CD14, APOH
30indomethacin43 28 59 1211.8NPPB, IL1R1, IFNA2
31lactate438.7APOH, IL1R1, NPPB, CD14
32creatinine438.7NPPB, CD14, IL1R1, APOH
33heparin43 28 24 1211.7NPPB, IL1R1, APOH, CD14
34arginine438.7CD14, NPPB, IL1R1, APOH
35phosphatidylinositol438.7CD14, IL1R1, APOH, NPPB
36histamine43 28 2410.6IFNA2, CD14, NPPB
37cyclophosphamide43 49 1210.5NPPB, IL1R1, IFNA2, APOH
38fatty acid438.5APOH, IL1R1, NPPB, IFNA2
39superoxide43 249.4APOH, IFNA2, NPPB, CD14
40progesterone43 28 59 24 1212.4IL1R1, APOH, IFNA2, NPPB
41zinc43 249.4IL1R1, NPPB, IFNA2, APOH
42oxygen43 249.4NPPB, IL1R1, APOH, IFNA2
43estrogen438.4NPPB, IL1R1, IFNA2, APOH
44cysteine438.3CD14, NPPB, IFNA2, IL1R1
45iron43 249.1IFNA2, NPPB, HFE2, IL1R1, APOH
46prednisolone43 28 1210.0CD14, IL1R1, IFNA2, NPPB, APOH
47steroid438.0IFNA2, IL1R1, NPPB, CD14, APOH
48vegf438.0NPPB, APOH, CD14, IL1R1, IFNA2
49glucose438.0IL1R1, CD14, APOH, IFNA2, NPPB
50lipid437.9APOH, IFNA2, CD14, IL1R1, NPPB

GO Terms for genes affiliated with Cardiogenic Shock

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Cellular components related to Cardiogenic Shock according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1anchored component of membraneGO:00312259.5CD14, HFE2
2cell surfaceGO:00099868.5APOH, IL1R1, HFE2, CD14
3extracellular regionGO:00055767.7CD14, NPPB, IL1R1, IFNA2
4extracellular spaceGO:00056157.6CD14, NPPB, HFE2, IFNA2, APOH

Biological processes related to Cardiogenic Shock according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of angiogenesisGO:00165259.4NPPB, APOH
2cell surface receptor signaling pathwayGO:00071667.7CD14, NPPB, IL1R1, IFNA2

Products for genes affiliated with Cardiogenic Shock

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Sources for Cardiogenic Shock

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet