MCID: CRD118
MIFTS: 45

Cardiovascular Cancer

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Cardiovascular Cancer

MalaCards integrated aliases for Cardiovascular Cancer:

Name: Cardiovascular Cancer 12 52 14
Cardiovascular Neoplasm 12 69
Cardiovascular Tumors 12

Classifications:



External Ids:

Disease Ontology 12 DOID:176
NCIt 47 C4784
UMLS 69 C0497243

Summaries for Cardiovascular Cancer

Disease Ontology : 12 An organ system cancer that located in the heart and blood vessels.

MalaCards based summary : Cardiovascular Cancer, also known as cardiovascular neoplasm, is related to striatonigral degeneration and heart cancer. An important gene associated with Cardiovascular Cancer is HBA1 (Hemoglobin Subunit Alpha 1), and among its related pathways/superpathways are Ras signaling pathway and Pathways in cancer. The drugs Heparin and Norepinephrine have been mentioned in the context of this disorder. Affiliated tissues include bone, heart and bone marrow, and related phenotypes are behavior/neurological and growth/size/body region

Related Diseases for Cardiovascular Cancer

Diseases related to Cardiovascular Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 94)
id Related Disease Score Top Affiliating Genes
1 striatonigral degeneration 10.8 CAMTA1 HBA1
2 heart cancer 10.7
3 vascular cancer 10.7
4 conventional angiosarcoma 10.6 HBA1 VEGFA
5 cutaneous liposarcoma 10.6 HBA1 KIT
6 salivary gland adenoid cystic carcinoma 10.6 HBA1 VEGFA
7 punctate palmoplantar keratoderma type 2 10.6 KDR KIT
8 fallopian tube serous papilloma 10.6 KIT MITF
9 impaired renal function disease 10.6 HBA1 PTH1R TSC2
10 papillary meningioma of the cerebellum 10.6 FLT4 HBA1
11 corneal staphyloma 10.5 CTSK PTH1R
12 schnitzler syndrome 10.5 CTSK MITF
13 breast secretory carcinoma 10.5 SLC2A1 VEGFA
14 alcohol-induced mental disorder 10.5 HBA1 KDR KIT
15 hyperlucent lung 10.5 FLT4 HBA1
16 adenoma 10.5 MITF VEGFA
17 thyroid angiosarcoma 10.4 HBA1 KIT MITF
18 fibrosarcoma of bone 10.4 HBA1 KIT
19 breast intracanalicular fibroadenoma 10.4 PTH1R SLC2A1
20 kasznica carlson coppedge syndrome 10.4 FLT4 KDR
21 hemangioma, capillary infantile 10.4 FLT4 KDR
22 bronchus cancer 10.4 CTSK PTH1R
23 iliac vein thrombophlebitis 10.4 KDR VEGFA
24 segmental odontomaxillary dysplasia 10.4 KDR VEGFA
25 gangliosidosis gm2 10.4 KIT MITF TSC2
26 pycnodysostosis 10.4 CTSK MITF
27 malignant sertoli-leydig cell tumor 10.3 KIT MME
28 pseudounicornuate uterus 10.3 KIT MME
29 middle cerebral artery infarction 10.3 MITF VEGFA
30 hypertonia 10.3 FLT4 VEGFA
31 gestational choriocarcinoma 10.3 HBA1 KIT VEGFA
32 angiomatosis, diffuse corticomeningeal, of divry and van bogaert 10.3 KDR MME
33 angelman syndrome due to a point mutation 10.3 MITF MME
34 posterior foramen magnum meningioma 10.3 HBA1 KDR VEGFA
35 coloboma of superior eyelid 10.3 CAMTA1 KDR VEGFA
36 sphenoid sinus squamous cell carcinoma 10.3 KIT MME
37 liver angiosarcoma 10.3 KIT MME
38 vernal conjunctivitis 10.3 HBA1 KDR VEGFA
39 lens disease 10.3 KDR VEGFA
40 kidney pelvis papillary carcinoma 10.2 KDR SLC2A1 VEGFA
41 hemi 3 syndrome 10.2 CAMTA1 FLT4 KDR
42 prostate disease 10.2 KIT SLC2A1
43 rectal neoplasm 10.2 KIT MME
44 uremia 10.2 HBA1 SYP
45 cauda equina intradural extramedullary astrocytoma 10.2 SYP TSC2
46 spiradenoma 10.2 KIT MME
47 invasive malignant thymoma 10.2 KIT SYP
48 connective tissue benign neoplasm 10.2 HBA1 MME SLC2A1
49 cauda equina neoplasm 10.1 SYP TSC2
50 gallbladder papillomatosis 10.1 KIT MME TSC2

Graphical network of the top 20 diseases related to Cardiovascular Cancer:



Diseases related to Cardiovascular Cancer

Symptoms & Phenotypes for Cardiovascular Cancer

MGI Mouse Phenotypes related to Cardiovascular Cancer:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.18 KDR KIT MITF PTH1R SFPQ SLC2A1
2 growth/size/body region MP:0005378 10.13 CAMTA1 CTSK FLT4 KDR KIT MITF
3 homeostasis/metabolism MP:0005376 10.1 CTSK FLT4 KDR KIT MITF MME
4 embryo MP:0005380 10.06 FLT4 KDR KIT MITF PTH1R SLC2A1
5 mortality/aging MP:0010768 9.96 SLC2A1 TSC2 VEGFA CAMTA1 FLT4 KDR
6 integument MP:0010771 9.91 FLT4 KDR KIT MITF MME TSC2
7 nervous system MP:0003631 9.81 CAMTA1 CTSK KDR KIT MITF SLC2A1
8 liver/biliary system MP:0005370 9.8 MME TSC2 VEGFA FLT4 KDR KIT
9 no phenotypic analysis MP:0003012 9.43 FLT4 KDR KIT MITF SLC2A1 VEGFA
10 normal MP:0002873 9.23 CAMTA1 FLT4 KDR KIT MITF SYP

Drugs & Therapeutics for Cardiovascular Cancer

Drugs for Cardiovascular Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1065)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9005-49-6 772 46507594
2
Norepinephrine Approved Phase 4,Phase 3,Phase 2 51-41-2 439260
3
Dopamine Approved Phase 4,Phase 1,Phase 2 51-61-6, 62-31-7 681
4
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-02-2 5743
5
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 23214-92-8 31703
6
Pioglitazone Approved, Investigational Phase 4,Phase 2 111025-46-8 4829
7
Simvastatin Approved Phase 4,Phase 3,Phase 2,Early Phase 1 79902-63-9 54454
8
Zinc Approved Phase 4,Phase 3,Phase 2,Early Phase 1 7440-66-6 32051 23994
9
Progesterone Approved, Vet_approved Phase 4,Phase 3 57-83-0 5994
10
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
11
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2 58-22-0 6013
12
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-78-2 2244
13
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-28-2 5757
14
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
15
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
16
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
17
Midazolam Approved, Illicit Phase 4,Phase 2 59467-70-8 4192
18
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 7439-89-6 23925
19
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
20
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
21
Pantoprazole Approved Phase 4 102625-70-7 4679
22
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
23
Acetaminophen Approved Phase 4,Phase 2,Phase 1 103-90-2 1983
24
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2 169590-42-5 2662
25
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1 657-24-9 14219 4091
26
Lisinopril Approved, Investigational Phase 4,Phase 2 83915-83-7, 76547-98-3 5362119
27
Telmisartan Approved, Investigational Phase 4,Phase 3 144701-48-4 65999
28
Amlodipine Approved Phase 4 88150-42-9 2162
29
Amiodarone Approved, Investigational Phase 4,Phase 3 1951-25-3 2157
30
Azathioprine Approved Phase 4,Phase 2,Phase 3 446-86-6 2265
31
Amphotericin B Approved, Investigational Phase 4,Phase 3,Phase 2 1397-89-3 14956 5280965
32
Ticlopidine Approved Phase 4 55142-85-3 5472
33
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
34
Drospirenone Approved Phase 4,Phase 3,Phase 1 67392-87-4 68873
35
Amiloride Approved Phase 4 2016-88-8, 2609-46-3 16231
36
Dobutamine Approved Phase 4,Phase 3 34368-04-2 36811
37
Bortezomib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 179324-69-7 387447 93860
38
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
39
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
40
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
41
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
42
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
43
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
44
Basiliximab Approved, Investigational Phase 4,Phase 3,Phase 2 152923-56-3, 179045-86-4
45
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
46
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 2078-54-8 4943
47
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 135968-09-1
48
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 124-94-7 31307
49
Emtricitabine Approved, Investigational Phase 4 143491-57-0 60877
50
Apixaban Approved Phase 4,Phase 3,Phase 2,Phase 1 503612-47-3 10182969

Interventional clinical trials:

(show top 50) (show all 3145)

id Name Status NCT ID Phase Drugs
1 Multi-centre Clinical Trial on Hormone Replacement Treatment in China Unknown status NCT01698164 Phase 4 estradiol plus MPA;Ximingting Tablet;estradiol plus progesterone
2 Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients Unknown status NCT01011660 Phase 4 Amlodipine, Telmisartan, Amiloride Compound , Simvastatin
3 The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Taking Aspirin Unknown status NCT01549418 Phase 4 Aspirin (ASA);Placebo
4 Serratus Anterior Plane Block Versus Paravertebral Block for Postmastectomy Analgesia Unknown status NCT02103946 Phase 4
5 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4 Folic acid, vitamin B6 and B12 or placebo
6 Does Early Re-administration of Aspirin/Clopidogrel Increase the Risk of Bleeding From Artificial Ulcer After EMR or ESD? Unknown status NCT01621451 Phase 4 aspirin and/or clopidogrel;aspirin and/or clopidogrel
7 Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation Unknown status NCT00903188 Phase 4 cyclosporine;Everolimus
8 Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis Unknown status NCT00450645 Phase 4 low molecular weight heparin
9 Quadratus Lumborum Block for Percutaneous Nephrostomy Unknown status NCT02121951 Phase 4 MAC
10 Vitamin D and Glucose Metabolism in Pediatrics Unknown status NCT01386736 Phase 4 Vitamin D drops;Placebo drops
11 Amiodarone Prophylaxis for Atrial Fibrillation in Patients Undergoing Surgery for Lung Cancer Unknown status NCT00724581 Phase 4 Amiodarone
12 HIV Persistence and Viral Reservoirs Unknown status NCT01025427 Phase 4 Raltegravir, tenofovir/emtricitabine
13 Study Effects of Ginkgo Biloba Extract on Endothelial Cell Function and Genetic Effects on the Response to Ginkgo Biloba Extract in Diabetic Patients With Stable Coronary Artery Disease Unknown status NCT01038050 Phase 4 Ginkgo Biloba Extract (GBE)
14 Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy Unknown status NCT01175486 Phase 4 Actos (Pioglitazone);Acarbose
15 Hepatic Resection Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma Complicated by Portal Vein Tumor Thrombosis Unknown status NCT01350206 Phase 4
16 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease Unknown status NCT01595750 Phase 4 Roflumilast 500;Placebo
17 The Therapeutic Effect of Bromocriptin in Patients With Primary Aldosteronism Unknown status NCT00451672 Phase 4 bromocriptine
18 Steroid Free Immunosuppression or Calcineurin Inhibitor Minimization After Basiliximab Induction Therapy in Kidney Transplantation: Comparison With a Standard Quadruple Immunosuppressive Regimen Unknown status NCT01560572 Phase 4 tacrolimus OD, mycophenolic acid, prednisolone
19 Efficacy Study of PAD and TAD in Newly Diagnosed Multiple Myeloma Unknown status NCT01249690 Phase 4 Bortezomib,Pirarubicin,Dexamethasone;Thalidomide,Pirarubicin,Dexamethasone
20 Dose Titration of Lisinopril in Children Aged 1 to 18 Years With Primary or Secondary Hypertension Unknown status NCT02184858 Phase 4 lisinopril, ACE-inhibitor
21 Calcineurin Inhibitor Minimisation in Renal Transplant Recipients With Stable Allograft Function Unknown status NCT00541814 Phase 4 Cyclosporine
22 Comparison of Laryngeal Mask Airway (LMA®) and Tracheal Tube in Modified Radical Mastectomy on Breast Cancer Completed NCT00638599 Phase 4
23 Oral Contraceptive and Cardiovascular Risk in PCOS Completed NCT00593294 Phase 4 OC - Drospirenone plus Ethynylestradiol
24 An Alternative to A Fixed Schedule In Management Of Prostate Cancer Completed NCT01056562 Phase 4
25 Tumor Necrosis Factors (TNF)-α Blockade for Psoriatic Arthritis Completed NCT00432406 Phase 4 Infliximab;Etanercept
26 Radical Prostatectomy and Perioperative Fluid Therapy Completed NCT00771966 Phase 4
27 Effect of 5 Years of GH Replacement on Atherosclerosis Completed NCT00462475 Phase 4 Recombinant Growth Hormone, Genotropin (Pfizer)
28 Ulinastatin's Anti-inflammatory Reaction in Cardiac Surgery Completed NCT01518569 Phase 4 ulinastatin;placebo
29 Protective Effect of EPA on Cardiovascular Events Completed NCT00231738 Phase 4 Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
30 Exercise and Phytoestrogens: Effect on Factors Predisposing to Cardiovascular Disease(CVD) in Postmenopausal Women Completed NCT01048606 Phase 4
31 Hydroxyethyl Starch and Renal Function After Radical Prostatectomy Completed NCT01486563 Phase 4 Voluven (Hydroxyethyl starch 130/0,4);Sodium Chloride 9 mg/ml
32 Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization Completed NCT02368054 Phase 4 Bupivacaine;Adrenaline
33 Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure Completed NCT00732693 Phase 4 Ethinylestradiol / Norethisterone;Estradiol / Progesterone
34 Dose Escalation of Octreotide-LAR as First-Line Therapy in Resistant Acromegaly Completed NCT00461149 Phase 4 Octreotide-LAR
35 Drug Interaction Study of Olmesartan in Healthy Chinese Volunteers Completed NCT01907373 Phase 4 olmesartan medoxomil;olmesartan medoxomil+probenecid
36 Anti-Inflammatory Actions of Valsartan in Patients With Type 2 Diabetes Mellitus Completed NCT00982358 Phase 4 Valsartan
37 C-Reactive Protein (CRP) in Obese Diabetic Women Completed NCT00262548 Phase 4 Rosuvastatin; improvement of lipid profile
38 Study in Cancer Patients With Central Line Associated Clots in the Upper Extremity Treated With Rivaroxaban (Catheter 2) Completed NCT01708850 Phase 4 Rivaroxaban
39 Radiation Exposure Reduction in Supraventricular Tachycardia Ablation Completed NCT01132274 Phase 4
40 Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer Completed NCT01989845 Phase 4 Rivaroxaban
41 Vitamin D Repletion in Stone Formers With Hypercalciuria Completed NCT01295879 Phase 4 Ergocalciferol
42 Development of Active Safety Surveillance System for Traditional Chinese Medicine Completed NCT00275964 Phase 4 TMN-1
43 Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout Completed NCT02500641 Phase 4 Febuxostat 80/120mg/day;Allopurinol 100 up to 600mg/day;Colchicine;Naproxen;Omeprazole
44 Garcinia Mangostana Extracts in the Management of Weight Loss Completed NCT02823561 Phase 4
45 Pioglitazone vs. Insulin Glargine in the Treatment of Secondary Drug Failure in Type 2 Diabetes Completed NCT00609856 Phase 4 pioglitazone;insulin glargine
46 Cancer Venous Thromboembolism (VTE) Completed NCT02073682 Phase 4 Edoxaban;Dalteparin
47 Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial Completed NCT01760967 Phase 4 Dexmedetomidine
48 Certican (Everolimus) for Recipients of Kidney From HLA-identical Living Donors Completed NCT01653041 Phase 4 Everolimus
49 Dalteparin for Primary Venous Thromboembolism (VTE) Prophylaxis in Pancreatic Cancer Patients Completed NCT00966277 Phase 4 Dalteparin
50 Effect of Renin Angiotensin System Blockade on the Fas Antigen (CD95) and Asymmetric Dimethylarginine (ADMA) Levels in Type-2 Diabetic Patients With Proteinuria Completed NCT00893425 Phase 4 ramipril

Search NIH Clinical Center for Cardiovascular Cancer

Genetic Tests for Cardiovascular Cancer

Anatomical Context for Cardiovascular Cancer

MalaCards organs/tissues related to Cardiovascular Cancer:

39
Bone, Heart, Bone Marrow, B Cells, Lung, Prostate, T Cells

Publications for Cardiovascular Cancer

Articles related to Cardiovascular Cancer:

id Title Authors Year
1
Antipsychotic treatment effects on cardiovascular, cancer, infection, and intentional self-harm as cause of death in patients with Alzheimer's dementia. ( 28199869 )
2017
2
Strong associations of 25-hydroxyvitamin D concentrations with all-cause, cardiovascular, cancer, and respiratory disease mortality in a large cohort study. ( 23446902 )
2013
3
Tocotrienols: potential drug targets for cardiovascular, cancer and neurological diseases. ( 21774777 )
2011
4
Cell cycle checkpoints: the role and evaluation for early diagnosis of senescence, cardiovascular, cancer, and neurodegenerative diseases. ( 17136506 )
2007
5
The effects of physical activity and body mass index on cardiovascular, cancer and all-cause mortality among 47 212 middle-aged Finnish men and women. ( 15724141 )
2005
6
On the relationship between all-cause, cardiovascular, cancer and residual mortality rates with age. ( 15785305 )
2005
7
Hillcrest Hospital campaigns in competitive Cleveland. Focus is on cardiovascular, cancer and pediatrics. ( 11467198 )
2001
8
The association of resting heart rate with cardiovascular, cancer and all-cause mortality. Eight year follow-up of 3527 male Israeli employees (the CORDIS Study) ( 10637085 )
2000

Variations for Cardiovascular Cancer

Expression for Cardiovascular Cancer

Search GEO for disease gene expression data for Cardiovascular Cancer.

Pathways for Cardiovascular Cancer

Pathways related to Cardiovascular Cancer according to GeneCards Suite gene sharing:

(show all 12)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.45 FLT4 KDR KIT VEGFA
2 12.35 KIT MITF SLC2A1 VEGFA
3 12.34 FLT4 KDR KIT TSC2 VEGFA
4 11.81 FLT4 KDR KIT
5
Show member pathways
11.79 FLT4 KDR KIT MITF TSC2 VEGFA
6 11.74 KDR MITF VEGFA
7
Show member pathways
11.51 FLT4 KDR VEGFA
8
Show member pathways
11.42 FLT4 KDR KIT
9 11.34 SLC2A1 SYP VEGFA
10
Show member pathways
11.18 FLT4 KDR KIT
11 10.87 KDR VEGFA
12 10.33 KDR SLC2A1 VEGFA

GO Terms for Cardiovascular Cancer

Cellular components related to Cardiovascular Cancer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.7 CAMTA1 CTSK FLT4 KDR KIT MME
2 neuron projection terminus GO:0044306 8.62 MME SYP

Biological processes related to Cardiovascular Cancer according to GeneCards Suite gene sharing:

(show all 17)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.77 FLT4 KDR KIT PTH1R VEGFA
2 regulation of cell shape GO:0008360 9.72 KDR KIT VEGFA
3 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.7 FLT4 KDR KIT
4 positive regulation of MAPK cascade GO:0043410 9.63 FLT4 KDR KIT
5 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.58 FLT4 KDR VEGFA
6 positive regulation of focal adhesion assembly GO:0051894 9.57 KDR VEGFA
7 bone resorption GO:0045453 9.56 CTSK PTH1R
8 melanocyte differentiation GO:0030318 9.54 KIT MITF
9 embryonic hemopoiesis GO:0035162 9.51 KDR KIT
10 positive regulation of endothelial cell proliferation GO:0001938 9.5 FLT4 KDR VEGFA
11 cell migration involved in sprouting angiogenesis GO:0002042 9.49 KDR VEGFA
12 positive regulation of positive chemotaxis GO:0050927 9.48 KDR VEGFA
13 positive regulation of protein kinase C signaling GO:0090037 9.43 FLT4 VEGFA
14 vascular endothelial growth factor signaling pathway GO:0038084 9.26 FLT4 KDR
15 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.16 KDR VEGFA
16 positive regulation of endothelial cell migration GO:0010595 9.13 FLT4 KDR VEGFA
17 cellular response to vascular endothelial growth factor stimulus GO:0035924 8.8 FLT4 KDR VEGFA

Molecular functions related to Cardiovascular Cancer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 9.62 KIT SFPQ TSC2 VEGFA
2 signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.26 KDR KIT
3 vascular endothelial growth factor-activated receptor activity GO:0005021 9.16 FLT4 KDR
4 protein self-association GO:0043621 9.13 PTH1R SLC2A1 SYP
5 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.8 FLT4 KDR KIT

Sources for Cardiovascular Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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