MCID: CRD144
MIFTS: 39

Cardiovascular Disease Risk Factor ) malady

Genetic diseases (common), Cardiovascular diseases categories

Aliases & Classifications for Cardiovascular Disease Risk Factor )

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Aliases & Descriptions for Cardiovascular Disease Risk Factor ):

Name: Cardiovascular Disease Risk Factor ) 22
Hyperlipoproteinemia Type Iii Risk Factor 22
 
Coronary Artery Disease Risk Factor ) 22
Coronay Artery Disease Risk Factor 22


Classifications:



Summaries for Cardiovascular Disease Risk Factor )

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MalaCards based summary: Cardiovascular Disease Risk Factor ), also known as hyperlipoproteinemia type iii risk factor, is related to artery disease and obesity. An important gene associated with Cardiovascular Disease Risk Factor ) is ACE (Angiotensin I Converting Enzyme), and among its related pathways are FOXA1 transcription factor network and ATF-2 transcription factor network. Affiliated tissues include heart, endothelial and ovary, and related mouse phenotypes are adipose tissue and liver/biliary system.

Related Diseases for Cardiovascular Disease Risk Factor )

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Diseases related to Cardiovascular Disease Risk Factor ) via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 167)
idRelated DiseaseScoreTop Affiliating Genes
1artery disease30.5ACE, APOB, PPARA, SELE, SERPINE1
2obesity30.5APOB, INS, PPARA, SERPINE1
3coronary artery disease30.3ACE, APOB, INS, SELE, SERPINE1, VWF
4hypertriglyceridemia30.2APOB, INS, SERPINE1
5myocardial infarction30.1ACE, APOB, SERPINE1, VWF
6hypoalphalipoproteinemia30.1APOB, PPARA
7hypertension, essential30.0ACE, APOB, SELE, SERPINE1, VWF
8stroke, ischemic30.0ACE, APOB, SERPINE1, VWF
9arthropathy29.7ACE, APOB, SELE, SERPINE1, VWF
10lipid storage disease29.6ACE, APOB, PPARA, SERPINE1
11vascular hemostatic disease29.5ACE, APOB, SELE, SERPINE1, VWF
12diabetes mellitus, insulin-dependent29.4ACE, APOB, INS, PPARA, SELE, SERPINE1
13diabetes mellitus, noninsulin-dependent29.2ACE, APOB, INS, PPARA, SELE, SERPINE1
14atherosclerosis10.6
15metabolic syndrome x10.5
16nutritional deficiency disease10.5
17lipid metabolism disorder10.5
18glucose metabolism disease10.5
19blood protein disease10.4
20gout10.4
21physical disorder10.4
22rheumatoid arthritis10.3
23coronary heart disease 610.3
24coronary heart disease 310.3
25pulmonary hypertension10.3
26arthritis10.3
27hemoglobin c disease10.3
28hyperuricemia10.3
29intermediate coronary syndrome10.3
30familial hyperlipidemia10.3
31endotheliitis10.3
32hiv-110.2
33diabetes mellitus, noninsulin-dependent 110.2
34coronary heart disease 510.2
35nicotine dependence, protection against10.2
36mody, type ii10.2
37diabetes mellitus, noninsulin-dependent, 210.2
38coronary heart disease 410.2
39hypercholesterolemia, familial10.2
40peripheral vascular disease10.2
41joint disorders10.2
42autoimmune disease of cardiovascular system10.2
43autoimmune disease of musculoskeletal system10.2
44gamma chain deficiency10.2
45conduct disorder10.2
46spastic diplegia10.2
47rheumatic congestive heart failure10.2
48hyperinsulinism10.2
49acquired immunodeficiency syndrome10.2
50arteriosclerosis10.2

Graphical network of the top 20 diseases related to Cardiovascular Disease Risk Factor ):



Diseases related to cardiovascular disease risk factor  )

Symptoms for Cardiovascular Disease Risk Factor )

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Drugs & Therapeutics for Cardiovascular Disease Risk Factor )

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Cardiovascular Disease Risk Factor )

Genetic Tests for Cardiovascular Disease Risk Factor )

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Genetic tests related to Cardiovascular Disease Risk Factor ):

id Genetic test Affiliating Genes
1 Cardiovascular Disease Risk Factor (angiotensin Converting Enzyme (ace))22 ACE
2 Cardiovascular Disease Risk Factor (angiotensin Ii Receptor, Type 1)22 AGTR1
3 Cardiovascular Disease Risk Factor (angiotensinogen)22 AGT
4 Cardiovascular Disease Risk Factor (apolipoprotein E)22 APOE
5 Cardiovascular Disease Risk Factor (carotid Intimal Medial Thickness 1)22 PPARG

Anatomical Context for Cardiovascular Disease Risk Factor )

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MalaCards organs/tissues related to Cardiovascular Disease Risk Factor ):

33
Heart, Endothelial, Ovary, Kidney, Spinal cord

Animal Models for Cardiovascular Disease Risk Factor ) or affiliated genes

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MGI Mouse Phenotypes related to Cardiovascular Disease Risk Factor ):

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.0ACE, INS, PPARA, SERPINE1
2MP:00053708.1ACE, APOB, INS, PPARA, SELE, SERPINE1
3MP:00053787.9ACE, APOB, INS, PPARA, SELE, SERPINE1
4MP:00053847.6ACE, CHRNA7, INS, PPARA, SELE, VWF
5MP:00053977.3ACE, CHRNA7, INS, SELE, SERPINE1, VWF
6MP:00053857.2ACE, APOB, INS, PPARA, SELE, SERPINE1
7MP:00107686.5ACE, APOB, CHRNA7, INS, PPARA, SELE
8MP:00053876.5ACE, CHRNA7, INS, PPARA, SELE, SERPINE1
9MP:00053766.3ACE, APOB, CHRNA7, INS, PPARA, SELE

Publications for Cardiovascular Disease Risk Factor )

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Articles related to Cardiovascular Disease Risk Factor ):

(show top 50)    (show all 151)
idTitleAuthorsYear
1
Outcomes of cardiovascular disease risk factor screening and referrals in a family planning clinic. (25517351)
2015
2
Trends in Cardiovascular Disease Risk Factor Prevalence and Estimated 10-Year Cardiovascular Risk Scores in a Large Untreated French Urban Population: The CARVAR 92 Study. (25906186)
2015
3
Heart matters: Gender and racial differences cardiovascular disease risk factor control among veterans. (25213741)
2014
4
Physician cardiovascular disease risk factor management: practice analysis in Japan versus the USA. (23735635)
2013
5
Associations of Cardiovascular Disease Risk Factors and Calcified Atherosclerosis With Aortoiliac Bifurcation Position: The Multiethnic Study of Atherosclerosis. (24375634)
2013
6
Immigration disparities in cardiovascular disease risk factor awareness. (22210443)
2012
7
Cardiovascular disease risk factor patterns and their implications for intervention strategies in Vietnam. (22500217)
2012
8
A review of family history of cardiovascular disease: risk factor and research tool. (22607505)
2012
9
Cardiovascular disease risk factors: prevalence and management in adult hemophilia patients. (21451396)
2011
10
Differences in cardiovascular disease risk factor management in primary care by sex of physician and patient. (20065275)
2010
11
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study. (20838585)
2010
12
Job demand and cardiovascular disease risk factor in white-collar workers. (20160403)
2010
13
Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. (19460605)
2009
14
Comprehensive genetic analysis of the dipeptidyl peptidase-4 gene and cardiovascular disease risk factors in obese individuals. (18682883)
2009
15
Demonstration of community pharmacy and managed care organization collaboration on cardiovascular disease risk factor identification using health risk appraisal. (19289349)
2009
16
Association of OSBPL11 gene polymorphisms with cardiovascular disease risk factors in obesity. (19325544)
2009
17
Association of BMI and fasting insulin with cardiovascular disease risk factors in seven-year-old Icelandic children. (19731182)
2009
18
Adipokines and systemic lupus erythematosus: relationship with metabolic syndrome and cardiovascular disease risk factors. (19132788)
2009
19
Association of human cathelicidin (hCAP-18/LL-37) gene expression with cardiovascular disease risk factors. (19346112)
2009
20
Analysis of postprandial lipemia as a Cardiovascular Disease risk factor using genetic and clinical information: an Artificial Neural Network perspective. (19163743)
2008
21
The association of ADH and ALDH gene variants with alcohol drinking habits and cardiovascular disease risk factors. (18782342)
2008
22
Cardiovascular disease risk factor screening among Alaska Native women: the traditions of the heart project. (18154231)
2007
23
Genes, fat intake, and cardiovascular disease risk factors in the Quebec Family Study. (17890503)
2007
24
Plasma leptin concentration in patients with Type 2 diabetes: relationship to cardiovascular disease risk factors and insulin resistance. (15717875)
2005
25
Coexistence of osteoporosis and cardiovascular disease risk factors in apparently healthy, untreated postmenopausal women. (15929631)
2005
26
Antithrombin III activity in the elderly--association with cardiovascular disease risk factors]. (16521916)
2005
27
Letter regarding article by Christou et al, "Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men". (16203921)
2005
28
Insulin-like growth factor-1, insulin-like growth factor binding protein-3, and cardiovascular disease risk factors in young black men and white men: the CARDIA Male Hormone Study. (15466497)
2004
29
Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy. (15113713)
2004
30
The influence of an intense cardiovascular disease risk factor modification program. (15010624)
2004
31
Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors. (12966036)
2003
32
Effects of an 8-week weight-loss program on cardiovascular disease risk factors and regional body composition. (12173568)
2002
33
Total and regional fat and serum cardiovascular disease risk factors in lean and obese children and adolescents. (11500523)
2001
34
Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men. (11472752)
2001
35
Quality improvement programme for cardiovascular disease risk factor recording in primary care. (10980078)
2000
36
Issues for cardiovascular disease risk factor development in Europe. (10641825)
1999
37
Endothelial dysfunction in cardiovascular disease: risk factor, risk marker, or surrogate end point? (9883752)
1998
38
Adverse effects of diabetes on multiple cardiovascular disease risk factors in women. The Strong Heart Study. (9702430)
1998
39
Prevalence of cardiovascular disease risk-factor clustering among persons aged > or = 45 years--Louisiana, 1991-1995. (9214569)
1997
40
Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors. (9270410)
1997
41
Values of blood coagulating factors vary with ambient temperature: the Cardiovascular Disease Risk Factor Two-Township Study in Taiwan. (8902310)
1996
42
The emergence of clinically abnormal levels of cardiovascular disease risk factor variables among young adults: the Bogalusa Heart Study. (8610086)
1995
43
Who participates in cardiovascular disease risk factor screenings? Experience with a religious organization-based program. (8279596)
1994
44
Blood pressure and other cardiovascular disease risk factors in black adults with sickle cell trait or glucose-6-phosphate dehydrogenase deficiency. (2369999)
1990
45
Measurement error and reliability in four pediatric cross-sectional surveys of cardiovascular disease risk factor variables--the Bogalusa Heart Study. (3492509)
1987
46
Characteristics of participants and nonparticipants in a community cardiovascular disease risk factor screening: the Minnesota Heart Health Program. (3453156)
1986
47
Cardiovascular disease risk factor variables during the first year of life. (495597)
1979
48
Cardiovascular disease risk factor variables in children at two successive years--the Bogalusa heart study. (218982)
1979
49
Serum high density lipoprotein and its relationship to cardiovascular disease risk factor variables in children--the Bogalusa heart study. (218070)
1979
50
Dietary studies and the relationship of diet to cardiovascular disease risk factor variables in 10-year-old children--The Bogalusa Heart Study. (623054)
1978

Variations for Cardiovascular Disease Risk Factor )

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Expression for genes affiliated with Cardiovascular Disease Risk Factor )

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Search GEO for disease gene expression data for Cardiovascular Disease Risk Factor ).

Pathways for genes affiliated with Cardiovascular Disease Risk Factor )

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Pathways related to Cardiovascular Disease Risk Factor ) according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7APOB, INS
29.6INS, SELE
3
Show member pathways
9.2APOB, INS, SERPINE1
49.0INS, PPARA, SERPINE1
5
Show member pathways
8.3APOB, SELE, SERPINE1, VWF

GO Terms for genes affiliated with Cardiovascular Disease Risk Factor )

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Cellular components related to Cardiovascular Disease Risk Factor ) according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endosome lumenGO:003190410.3APOB, INS
2platelet alpha granule lumenGO:00310939.7SERPINE1, VWF
3external side of plasma membraneGO:00098979.1ACE, CHRNA7, VWF
4extracellular spaceGO:00056158.4ACE, APOB, INS, SELE, SERPINE1
5extracellular regionGO:00055767.7ACE, APOB, INS, SERPINE1, VWF

Biological processes related to Cardiovascular Disease Risk Factor ) according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipoprotein metabolic processGO:004215710.0APOB, PPARA
2sperm motilityGO:00303179.6APOB, CHRNA7
3regulation of inflammatory responseGO:00507279.6CHRNA7, SELE
4behavioral response to nicotineGO:00350959.6CHRNA7, PPARA
5blood coagulationGO:00075968.3APOB, SELE, SERPINE1, VWF

Molecular functions related to Cardiovascular Disease Risk Factor ) according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1drug bindingGO:00081449.0ACE, CHRNA7, PPARA
2protease bindingGO:00020208.9INS, SERPINE1, VWF

Sources for Cardiovascular Disease Risk Factor )

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet