MCID: CRD144
MIFTS: 37

Cardiovascular Disease Risk Factor ) malady

Categories: Genetic diseases (common), Cardiovascular diseases

Aliases & Classifications for Cardiovascular Disease Risk Factor )

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Aliases & Descriptions for Cardiovascular Disease Risk Factor ):

Name: Cardiovascular Disease Risk Factor ) 22
Hyperlipoproteinemia Type Iii Risk Factor 22
Coronary Artery Disease Risk Factor ) 22
 
Coronary Artery Disease Risk Factor 22
Coronay Artery Disease Risk Factor 22
Cardiovascular Disease Risk Factor 22

Classifications:



Summaries for Cardiovascular Disease Risk Factor )

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MalaCards based summary: Cardiovascular Disease Risk Factor ), also known as hyperlipoproteinemia type iii risk factor, is related to thyroid cancer and obesity. An important gene associated with Cardiovascular Disease Risk Factor ) is ACE (Angiotensin I Converting Enzyme), and among its related pathways are FOXA1 transcription factor network and ATF-2 transcription factor network. Affiliated tissues include bone, thyroid and breast, and related mouse phenotypes are adipose tissue and immune system.

Related Diseases for Cardiovascular Disease Risk Factor )

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Diseases related to Cardiovascular Disease Risk Factor ) via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 155)
idRelated DiseaseScoreTop Affiliating Genes
1thyroid cancer29.6ACE, APOB, SERPINE1
2obesity29.5APOB, INS, PPARA, SERPINE1
3mthfr thermolabile variant11.6
4metaphyseal dysplasia10.2APOB, SERPINE1
5ischemic optic neuropathy10.2ACE, APOB
6salivary gland cancer10.2INS, SELE
7inferior myocardial infarction10.2SELE, SERPINE1
8retinitis pigmentosa 1710.1ACE, INS
9prostate cancer10.1
10prostatitis10.1
11conjunctivochalasis10.1APOB, SERPINE1
12gestational diabetes10.1INS, SELE
13stickler sydrome, type i, nonsyndromic ocular10.1SELE, SERPINE1
14pyrimidine metabolic disorder10.1ACE, APOB
15congenital diaphragmatic hernia10.1SELE, SERPINE1
16heterophyiasis10.1ACE, SERPINE1
17thumb absent short stature immune deficiency10.1SELE, SERPINE1
18carotid artery thrombosis10.1ACE, APOB
19intraocular lymphoma10.1ACE, SERPINE1
20paralytic lagophthalmos10.0ACE, PPARA
21placental choriocarcinoma10.0APOB, INS, SERPINE1
22immunodeficiency 1910.0APOB, INS, SERPINE1
23diamond-blackfan anemia10.0ACE, INS
24leukemia10.0
25pemphigus vulgaris10.0
26dermatitis10.0
27epidermolysis bullosa10.0
28adenocarcinoma10.0
29thyroiditis10.0
30hyperthyroidism10.0
31pemphigus10.0
32hypotonia10.0
33apolipoprotein c-iii deficiency10.0APOB, PPARA
34codas syndrome10.0ACE, APOB, INS
35breast cancer9.9
36myelofibrosis9.9
37stroke, ischemic9.9ACE, APOB, SERPINE1
38adult acute lymphocytic leukemia9.9ACE, SERPINE1
39autistic disorder9.9APOB, SELE, SERPINE1
40citrullinemia, adult-onset type ii9.9ACE, INS, SERPINE1
41chronic venous insufficiency9.9ACE, SELE
42melanoacanthoma9.9APOB, PPARA, SERPINE1
43lymphedema9.8INS, PPARA, SERPINE1
44neuroblastoma9.8
45fucosidosis9.8
46lung cancer9.8
47leprosy9.8
48hyperprolactinemia9.8
49alzheimer disease9.8
50sickle cell anemia9.8

Graphical network of the top 20 diseases related to Cardiovascular Disease Risk Factor ):



Diseases related to cardiovascular disease risk factor  )

Symptoms for Cardiovascular Disease Risk Factor )

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Drugs & Therapeutics for Cardiovascular Disease Risk Factor )

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Cardiovascular Disease Risk Factor )

Genetic Tests for Cardiovascular Disease Risk Factor )

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Genetic tests related to Cardiovascular Disease Risk Factor ):

id Genetic test Affiliating Genes
1 Cardiovascular Disease Risk Factor (angiotensin Converting Enzyme (ace))22 ACE
2 Cardiovascular Disease Risk Factor (angiotensin Ii Receptor, Type 1)22 AGTR1
3 Cardiovascular Disease Risk Factor (angiotensinogen)22 AGT
4 Cardiovascular Disease Risk Factor (apolipoprotein E)22 APOE
5 Cardiovascular Disease Risk Factor (carotid Intimal Medial Thickness 1)22 PPARG

Anatomical Context for Cardiovascular Disease Risk Factor )

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MalaCards organs/tissues related to Cardiovascular Disease Risk Factor ):

33
Bone, Thyroid, Breast, Endothelial, Testes, Prostate, Eye

Animal Models for Cardiovascular Disease Risk Factor ) or affiliated genes

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MGI Mouse Phenotypes related to Cardiovascular Disease Risk Factor ):

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.5ACE, INS, PPARA, SERPINE1
2MP:00053877.2ACE, CHRNA7, INS, PPARA, SELE, SERPINE1
3MP:00053707.1ACE, APOB, CHRNA7, INS, PPARA, SELE
4MP:00053857.0ACE, APOB, INS, PPARA, SELE, SERPINE1
5MP:00053766.8ACE, APOB, CHRNA7, INS, PPARA, SELE
6MP:00107686.7ACE, APOB, CHRNA7, INS, PPARA, SELE
7MP:00053786.6ACE, APOB, CHRNA7, INS, PPARA, SELE

Publications for Cardiovascular Disease Risk Factor )

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Articles related to Cardiovascular Disease Risk Factor ):

(show top 50)    (show all 151)
idTitleAuthorsYear
1
Birt-Hogg-DubAc syndrome: a large single family cohort. (26928018)
2016
2
Cholera toxin B: one subunit with many pharmaceutical applications. (25802972)
2015
3
Pre- and post-therapy (18)F-FDG PET/CT of a patient affected by non-HIV multicentric IgG4-related Castleman disease. (26770956)
2015
4
Pseudosyndactyly - an inflammatory and fibrotic wound healing disorder in recessive dystrophic epidermolysis bullosa. (26612796)
2015
5
Ainhum: A Spot Diagnosis. (27011582)
2015
6
Traumatic stress, oxidative stress and post-traumatic stress disorder: neurodegeneration and the accelerated-aging hypothesis. (25245500)
2014
7
Cutl1: a potential target for cancer therapy. (23085261)
2013
8
GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation. (24121663)
2013
9
Reduced grey matter perfusion without volume loss in early relapsing-remitting multiple sclerosis. (24039024)
2013
10
Basophil Activation Test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy. (24327387)
2013
11
MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features. (22925189)
2012
12
A fatal case of bone marrow embolism of unknown cause masquerading clinically as dengue shock syndrome. (23455811)
2012
13
Elevation of plasma soluble CD26 levels during pregnancy. (21917073)
2012
14
The relationship between secretory leukocyte protease inhibitor expression and Epstein-Barr virus status among patients with nasopharyngeal carcinoma. (22493362)
2012
15
Synthetic human monoclonal antibodies toward staphylococcal enterotoxin B (SEB) protective against toxic shock syndrome. (22645125)
2012
16
Tension pneumothorax accompanied by type A aortic dissection. (23144347)
2012
17
Transmission of human African trypanosomiasis in the Komo-Mondah focus, Gabon. (22121444)
2011
18
Impact of seroconversion and antichlamydial treatment on the rate of pre-eclampsia among Egyptian primigravidae. (21334621)
2011
19
Subgingival Epstein-Barr and cytomegalovirus occurrence in pregnancy gingivitis. (21513469)
2011
20
Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the risk of type 2 diabetes in 5,164 Indians. (20424228)
2010
21
Role of genetic polymorphism of estrogen receptor-alpha gene and risk of prostate cancer in north Indian population. (19904497)
2010
22
Safety and preliminary efficacy of plerixafor (Mozobil) in combination with chemotherapy and G-CSF: an open-label, multicenter, exploratory trial in patients with multiple myeloma and non-Hodgkin's lymphoma undergoing stem cell mobilization. (19483760)
2010
23
Open and arthroscopic management of lateral epicondylitis in the athlete. (19643333)
2009
24
Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene. (19497887)
2009
25
An ancient genetic link between vertebrate mitochondrial fatty acid synthesis and RNA processing. (17898086)
2008
26
Cor triatriatum presenting in adulthood: a case report. (17442431)
2008
27
Investigation into the seasonal salmonellosis in lactating dairy cattle. (17506921)
2008
28
Evidence against a role for NADPH oxidase modulating hepatic vascular tone in cirrhosis. (17854599)
2007
29
Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. (17560375)
2007
30
Drug targets from human pathogenic amoebas: Entamoeba histolytica, Acanthamoeba polyphaga and Naegleria fowleri. (17897063)
2007
31
Pump-probe molecular dynamics as a tool for studying protein motion and long range coupling. (16933296)
2006
32
Pathological and physiological functions of presenilins. (16930451)
2006
33
Histamine H(4) receptors on mammary epithelial cells of the human breast with different types of carcinoma. (16547802)
2006
34
Overexpression of the insulin-like growth factor I receptor in human pheochromocytomas. (16595699)
2006
35
Repeated measurement of nasal lavage fluid chemokines in school-age children with asthma. (16498852)
2006
36
Expression profile of mRNAs from human pancreatic islet tumors. (14664712)
2003
37
Re-evaluation of MRX36 family after discovery of an ARX gene mutation reveals mild neurological features of Partington syndrome. (12376949)
2002
38
Functional characterization of TEL/AML1 fusion protein in the regulation of human CR1 gene promoter. (10597047)
1999
39
Massive disseminated intravascular coagulation and hyperfibrinolysis in alveolar rhabdomyosarcoma: case report and review of the literature. (10466447)
1999
40
One additional mutation at exon A amplifies thermolability of androgen receptor in a case with complete androgen insensitivity syndrome. (9610419)
1998
41
Of mites and men: trypsin-like proteases in the lungs. (9191463)
1997
42
First report of mycetoma caused by Arthrographis kalrae: successful treatment with itraconazole. (9270537)
1997
43
Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis. (8670172)
1996
44
Erythrocytosis in patients with renal failure on hemodialysis: study of underlying mechanism by in vitro erythroid culture assay. (8330648)
1993
45
Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts. (7689564)
1993
46
Unregulated and basal transcriptional activities of the regulatory sequence of the type 18 human papillomavirus genome in transgenic mice. (1314463)
1992
47
Infantile neuroaxonal dystrophy. Ultrastructural study of peripheral nerve. (184642)
1976
48
Trichinosis in the Vancouver area; examination of 400 human diaphragms. (13042710)
1953
49
50

Variations for Cardiovascular Disease Risk Factor )

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Expression for genes affiliated with Cardiovascular Disease Risk Factor )

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Search GEO for disease gene expression data for Cardiovascular Disease Risk Factor ).

Pathways for genes affiliated with Cardiovascular Disease Risk Factor )

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Pathways related to Cardiovascular Disease Risk Factor ) according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6APOB, INS
29.4INS, SELE
3
Show member pathways
9.1APOB, INS, SERPINE1
48.7INS, PPARA, SERPINE1

GO Terms for genes affiliated with Cardiovascular Disease Risk Factor )

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Biological processes related to Cardiovascular Disease Risk Factor ) according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1wound healingGO:00420609.4INS, PPARA
2lipid metabolic processGO:00066299.1APOB, PPARA
3positive regulation of angiogenesisGO:00457669.1CHRNA7, SERPINE1
4circadian rhythmGO:00076239.1PPARA, SERPINE1

Sources for Cardiovascular Disease Risk Factor )

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet