MCID: CRD053
MIFTS: 41

Cardiovascular Disease Risk Factor malady

Genetic diseases (common), Cardiovascular diseases categories
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Summaries for Cardiovascular Disease Risk Factor

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MalaCards based summary: Cardiovascular Disease Risk Factor is related to gout and hypercholesterolemia. An important gene associated with Cardiovascular Disease Risk Factor is AGTR1 (angiotensin II receptor, type 1), and among its related pathways is Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. The compounds quinapril and furosemide have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and spinal cord, and related mouse phenotype immune system.

Aliases & Classifications for Cardiovascular Disease Risk Factor

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Cardiovascular Disease Risk Factor, Aliases & Descriptions:

Name: Cardiovascular Disease Risk Factor 20


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)
Anatomical: Cardiovascular diseases


Related Diseases for Cardiovascular Disease Risk Factor

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Graphical network of the top 20 diseases related to Cardiovascular Disease Risk Factor:



Diseases related to cardiovascular disease risk factor

Symptoms for Cardiovascular Disease Risk Factor

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Drugs & Therapeutics for Cardiovascular Disease Risk Factor

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Drug clinical trials:

Search ClinicalTrials for Cardiovascular Disease Risk Factor

Search NIH Clinical Center for Cardiovascular Disease Risk Factor

Genetic Tests for Cardiovascular Disease Risk Factor

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Genetic tests related to Cardiovascular Disease Risk Factor:

id Genetic test Affiliating Genes
1 Cardiovascular Disease Risk Factor (angiotensin Ii Receptor, Type 1)20 AGTR1
2 Cardiovascular Disease Risk Factor (angiotensinogen)20 AGT
3 Cardiovascular Disease Risk Factor (apolipoprotein E)20 APOE
4 Cardiovascular Disease Risk Factor (angiotensin Converting Enzyme (ace))20 ACE
5 Cardiovascular Disease Risk Factor (carotid Intimal Medial Thickness 1)20 PPARG

Anatomical Context for Cardiovascular Disease Risk Factor

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MalaCards organs/tissues related to Cardiovascular Disease Risk Factor:

32
Heart, Endothelial, Spinal cord, Kidney

Animal Models for Cardiovascular Disease Risk Factor or affiliated genes

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MGI Mouse Phenotypes related to Cardiovascular Disease Risk Factor:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.7FGF23, AGTR1, CAMP, SELE, FCGR2B

Publications for Cardiovascular Disease Risk Factor

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Articles related to Cardiovascular Disease Risk Factor:

(show top 50)    (show all 139)
idTitleAuthorsYear
1
Heart matters: Gender and racial differences cardiovascular disease risk factor control among veterans. (25213741)
2014
2
Physician cardiovascular disease risk factor management: practice analysis in Japan versus the USA. (23735635)
2013
3
Associations of Cardiovascular Disease Risk Factors and Calcified Atherosclerosis With Aortoiliac Bifurcation Position: The Multiethnic Study of Atherosclerosis. (24375634)
2013
4
Immigration disparities in cardiovascular disease risk factor awareness. (22210443)
2012
5
Cardiovascular disease risk factor patterns and their implications for intervention strategies in Vietnam. (22500217)
2012
6
A review of family history of cardiovascular disease: risk factor and research tool. (22607505)
2012
7
Cardiovascular disease risk factors: prevalence and management in adult hemophilia patients. (21451396)
2011
8
Differences in cardiovascular disease risk factor management in primary care by sex of physician and patient. (20065275)
2010
9
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study. (20838585)
2010
10
Job demand and cardiovascular disease risk factor in white-collar workers. (20160403)
2010
11
Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. (19460605)
2009
12
Comprehensive genetic analysis of the dipeptidyl peptidase-4 gene and cardiovascular disease risk factors in obese individuals. (18682883)
2009
13
Demonstration of community pharmacy and managed care organization collaboration on cardiovascular disease risk factor identification using health risk appraisal. (19289349)
2009
14
Association of OSBPL11 gene polymorphisms with cardiovascular disease risk factors in obesity. (19325544)
2009
15
Association of BMI and fasting insulin with cardiovascular disease risk factors in seven-year-old Icelandic children. (19731182)
2009
16
Adipokines and systemic lupus erythematosus: relationship with metabolic syndrome and cardiovascular disease risk factors. (19132788)
2009
17
Association of human cathelicidin (hCAP-18/LL-37) gene expression with cardiovascular disease risk factors. (19346112)
2009
18
Analysis of postprandial lipemia as a Cardiovascular Disease risk factor using genetic and clinical information: an Artificial Neural Network perspective. (19163743)
2008
19
The association of ADH and ALDH gene variants with alcohol drinking habits and cardiovascular disease risk factors. (18782342)
2008
20
Cardiovascular disease risk factors and the relationships with physical activity, aerobic fitness, and body fat in adolescents and young adults with myelomeningocele. (18835477)
2008
21
Cardiovascular disease risk factor screening among Alaska Native women: the traditions of the heart project. (18154231)
2007
22
Genes, fat intake, and cardiovascular disease risk factors in the Quebec Family Study. (17890503)
2007
23
Plasma leptin concentration in patients with Type 2 diabetes: relationship to cardiovascular disease risk factors and insulin resistance. (15717875)
2005
24
Coexistence of osteoporosis and cardiovascular disease risk factors in apparently healthy, untreated postmenopausal women. (15929631)
2005
25
Antithrombin III activity in the elderly--association with cardiovascular disease risk factors]. (16521916)
2005
26
Letter regarding article by Christou et al, "Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men". (16203921)
2005
27
Insulin-like growth factor-1, insulin-like growth factor binding protein-3, and cardiovascular disease risk factors in young black men and white men: the CARDIA Male Hormone Study. (15466497)
2004
28
Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy. (15113713)
2004
29
The influence of an intense cardiovascular disease risk factor modification program. (15010624)
2004
30
Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors. (12966036)
2003
31
Effects of an 8-week weight-loss program on cardiovascular disease risk factors and regional body composition. (12173568)
2002
32
Total and regional fat and serum cardiovascular disease risk factors in lean and obese children and adolescents. (11500523)
2001
33
Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men. (11472752)
2001
34
Systemic inflammation as a cardiovascular disease risk factor and as a potential target for drug therapy. (11975814)
2001
35
Quality improvement programme for cardiovascular disease risk factor recording in primary care. (10980078)
2000
36
Issues for cardiovascular disease risk factor development in Europe. (10641825)
1999
37
Endothelial dysfunction in cardiovascular disease: risk factor, risk marker, or surrogate end point? (9883752)
1998
38
Adverse effects of diabetes on multiple cardiovascular disease risk factors in women. The Strong Heart Study. (9702430)
1998
39
Prevalence of cardiovascular disease risk-factor clustering among persons aged > or = 45 years--Louisiana, 1991-1995. (9214569)
1997
40
Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors. (9270410)
1997
41
Values of blood coagulating factors vary with ambient temperature: the Cardiovascular Disease Risk Factor Two-Township Study in Taiwan. (8902310)
1996
42
The emergence of clinically abnormal levels of cardiovascular disease risk factor variables among young adults: the Bogalusa Heart Study. (8610086)
1995
43
Who participates in cardiovascular disease risk factor screenings? Experience with a religious organization-based program. (8279596)
1994
44
Blood pressure and other cardiovascular disease risk factors in black adults with sickle cell trait or glucose-6-phosphate dehydrogenase deficiency. (2369999)
1990
45
Measurement error and reliability in four pediatric cross-sectional surveys of cardiovascular disease risk factor variables--the Bogalusa Heart Study. (3492509)
1987
46
Characteristics of participants and nonparticipants in a community cardiovascular disease risk factor screening: the Minnesota Heart Health Program. (3453156)
1986
47
Cardiovascular disease risk factor variables during the first year of life. (495597)
1979
48
Cardiovascular disease risk factor variables in children at two successive years--the Bogalusa heart study. (218982)
1979
49
Serum high density lipoprotein and its relationship to cardiovascular disease risk factor variables in children--the Bogalusa heart study. (218070)
1979
50
Dietary studies and the relationship of diet to cardiovascular disease risk factor variables in 10-year-old children--The Bogalusa Heart Study. (623054)
1978

Variations for Cardiovascular Disease Risk Factor

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Expression for genes affiliated with Cardiovascular Disease Risk Factor

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Expression patterns in normal tissues for genes affiliated with Cardiovascular Disease Risk Factor

Search GEO for disease gene expression data for Cardiovascular Disease Risk Factor.

Pathways for genes affiliated with Cardiovascular Disease Risk Factor

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Compounds for genes affiliated with Cardiovascular Disease Risk Factor

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Compounds related to Cardiovascular Disease Risk Factor according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1quinapril44 50 1112.1AGTR1, SELE
2furosemide44 61 28 50 24 1115.0SLC22A11, AGTR1
3carvedilol44 50 28 1113.0AGTR1, SELE
48-isoprostane4410.0AGTR1, SELE
5fluvastatin44 50 28 1112.9AGTR1, SELE
6cimetidine44 28 1111.9SELE, SLC22A11
7polymyxin b449.8SELE, CAMP
8lipoteichoic acid449.8CAMP, SELE
9iloprost61 28 44 1112.8CAMP, SELE
10losartan44 50 28 1112.8AGTR1, SELE
11rolipram44 61 2811.8SELE, CAMP
12pravastatin44 50 28 24 1113.7AGTR1, SLC22A11, SELE
13uric acid44 2410.6AGTR1, GCKR
14isoproterenol44 1110.5SELE, CAMP, AGTR1
15prostacyclin449.5AGTR1, CAMP, SELE
16estradiol44 24 1111.5AGTR1, SLC22A11, CAMP
17actinomycin d449.4SELE, CAMP, AGTR1
1825-hydroxyvitamin d449.4FGF23, CAMP
19sodium44 2410.4CAMP, SLC17A1, AGTR1
20histamine44 28 2411.2FCGR2B, SELE, CAMP
21vitamin d449.1CAMP, AGTR1, FGF23
221,25 dihydroxy vitamin d3449.0CAMP, FGF23
23creatinine449.0FGF23, AGTR1, SELE
24genistein44 28 61 2 24 1113.9AGTR1, CAMP, SELE, FCGR2B
25cholesterol44 28 24 1111.9AGTR1, CAMP, SELE
26heparin44 28 24 1111.7SELE, CAMP, AGTR1, FGF23
27lipid448.4FCGR2B, SELE, CAMP, GCKR, AGTR1
28tyrosine448.2FGF23, AGTR1, CAMP, FCGR2B
29serine448.1FCGR2B, SELE, CAMP, AGTR1, FGF23

GO Terms for genes affiliated with Cardiovascular Disease Risk Factor

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Biological processes related to Cardiovascular Disease Risk Factor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1calcium-mediated signalingGO:0197229.6AGTR1, SELE
2regulation of inflammatory responseGO:0507279.4SELE, AGTR1
3urate metabolic processGO:0464159.2SLC22A11, SLC17A1, GCKR
4transmembrane transportGO:0550859.2SLC22A11, SLC17A1, GCKR

Molecular functions related to Cardiovascular Disease Risk Factor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.3AGTR1, SLC22A11, GCKR, CAMP, STX16, SELE

Products for genes affiliated with Cardiovascular Disease Risk Factor

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  • Antibodies
  • Proteins
  • Lysates

Sources for Cardiovascular Disease Risk Factor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet