MCID: CRD053
MIFTS: 40

Cardiovascular Disease Risk Factor malady

Genetic diseases (common), Cardiovascular diseases categories

Summaries for Cardiovascular Disease Risk Factor

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34MalaCards
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MalaCards: Cardiovascular Disease Risk Factor is related to gout and atherosclerosis. An important gene associated with Cardiovascular Disease Risk Factor is AGTR1 (angiotensin II receptor, type 1), and among its related pathways is Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. The compounds quinapril and furosemide have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and spinal cord, and related mouse phenotype immune system.

Aliases & Classifications for Cardiovascular Disease Risk Factor

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21GeneTests
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

cardiovascular disease risk factor 21


Related Diseases for Cardiovascular Disease Risk Factor

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Cardiovascular Disease Risk Factor:



Diseases related to cardiovascular disease risk factor

Symptoms for Cardiovascular Disease Risk Factor

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Drugs & Therapeutics for Cardiovascular Disease Risk Factor

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Cardiovascular Disease Risk Factor

Drug clinical trials:

Search ClinicalTrials for Cardiovascular Disease Risk Factor

Search NIH Clinical Center for Cardiovascular Disease Risk Factor

Search CenterWatch for Cardiovascular Disease Risk Factor

Genetic Tests for Cardiovascular Disease Risk Factor

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21GeneTests
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Genetic tests related to Cardiovascular Disease Risk Factor:

id Genetic test Affiliating Genes
1 Cardiovascular Disease Risk Factor (angiotensin Ii Receptor, Type 1)21 AGTR1
2 Cardiovascular Disease Risk Factor (angiotensinogen)21 AGT
3 Cardiovascular Disease Risk Factor (apolipoprotein E)21 APOE
4 Cardiovascular Disease Risk Factor (angiotensin Converting Enzyme (ace))21 ACE
5 Cardiovascular Disease Risk Factor (carotid Intimal Medial Thickness 1)21 PPARG

Anatomical Context for Cardiovascular Disease Risk Factor

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34MalaCards
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MalaCards organs/tissues related to Cardiovascular Disease Risk Factor:

34
Heart, Endothelial, Spinal cord, Kidney

Animal Models for Cardiovascular Disease Risk Factor or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Cardiovascular Disease Risk Factor:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.7FGF23, AGTR1, CAMP, SELE, FCGR2B

Publications for Cardiovascular Disease Risk Factor

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53PubMed
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Articles related to Cardiovascular Disease Risk Factor:

(show top 50)    (show all 139)
idTitleAuthorsYear
1
Physician cardiovascular disease risk factor management: practice analysis in Japan versus the USA. (23735635)
2013
2
Associations of Cardiovascular Disease Risk Factors and Calcified Atherosclerosis With Aortoiliac Bifurcation Position: The Multiethnic Study of Atherosclerosis. (24375634)
2013
3
Immigration disparities in cardiovascular disease risk factor awareness. (22210443)
2012
4
Cardiovascular disease risk factor patterns and their implications for intervention strategies in Vietnam. (22500217)
2012
5
A review of family history of cardiovascular disease: risk factor and research tool. (22607505)
2012
6
Cardiovascular disease risk factors: prevalence and management in adult hemophilia patients. (21451396)
2011
7
Differences in cardiovascular disease risk factor management in primary care by sex of physician and patient. (20065275)
2010
8
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study. (20838585)
2010
9
Job demand and cardiovascular disease risk factor in white-collar workers. (20160403)
2010
10
A comparative analysis of the cardiovascular disease risk factor profiles of Pacific peoples and Europeans living in New Zealand assessed in routine primary care: PREDICT CVD-11. (20186243)
2010
11
Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. (19460605)
2009
12
Comprehensive genetic analysis of the dipeptidyl peptidase-4 gene and cardiovascular disease risk factors in obese individuals. (18682883)
2009
13
Demonstration of community pharmacy and managed care organization collaboration on cardiovascular disease risk factor identification using health risk appraisal. (19289349)
2009
14
Association of OSBPL11 gene polymorphisms with cardiovascular disease risk factors in obesity. (19325544)
2009
15
Association of BMI and fasting insulin with cardiovascular disease risk factors in seven-year-old Icelandic children. (19731182)
2009
16
Adipokines and systemic lupus erythematosus: relationship with metabolic syndrome and cardiovascular disease risk factors. (19132788)
2009
17
Association of human cathelicidin (hCAP-18/LL-37) gene expression with cardiovascular disease risk factors. (19346112)
2009
18
Analysis of postprandial lipemia as a Cardiovascular Disease risk factor using genetic and clinical information: an Artificial Neural Network perspective. (19163743)
2008
19
The association of ADH and ALDH gene variants with alcohol drinking habits and cardiovascular disease risk factors. (18782342)
2008
20
Cardiovascular disease risk factors and the relationships with physical activity, aerobic fitness, and body fat in adolescents and young adults with myelomeningocele. (18835477)
2008
21
Cardiovascular disease risk factor screening among Alaska Native women: the traditions of the heart project. (18154231)
2007
22
Genes, fat intake, and cardiovascular disease risk factors in the Quebec Family Study. (17890503)
2007
23
Plasma leptin concentration in patients with Type 2 diabetes: relationship to cardiovascular disease risk factors and insulin resistance. (15717875)
2005
24
Coexistence of osteoporosis and cardiovascular disease risk factors in apparently healthy, untreated postmenopausal women. (15929631)
2005
25
Antithrombin III activity in the elderly--association with cardiovascular disease risk factors]. (16521916)
2005
26
Letter regarding article by Christou et al, "Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men". (16203921)
2005
27
Insulin-like growth factor-1, insulin-like growth factor binding protein-3, and cardiovascular disease risk factors in young black men and white men: the CARDIA Male Hormone Study. (15466497)
2004
28
Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy. (15113713)
2004
29
The influence of an intense cardiovascular disease risk factor modification program. (15010624)
2004
30
Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors. (12966036)
2003
31
Effects of an 8-week weight-loss program on cardiovascular disease risk factors and regional body composition. (12173568)
2002
32
Total and regional fat and serum cardiovascular disease risk factors in lean and obese children and adolescents. (11500523)
2001
33
Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men. (11472752)
2001
34
Systemic inflammation as a cardiovascular disease risk factor and as a potential target for drug therapy. (11975814)
2001
35
Quality improvement programme for cardiovascular disease risk factor recording in primary care. (10980078)
2000
36
Issues for cardiovascular disease risk factor development in Europe. (10641825)
1999
37
Endothelial dysfunction in cardiovascular disease: risk factor, risk marker, or surrogate end point? (9883752)
1998
38
Adverse effects of diabetes on multiple cardiovascular disease risk factors in women. The Strong Heart Study. (9702430)
1998
39
Prevalence of cardiovascular disease risk-factor clustering among persons aged > or = 45 years--Louisiana, 1991-1995. (9214569)
1997
40
Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors. (9270410)
1997
41
Values of blood coagulating factors vary with ambient temperature: the Cardiovascular Disease Risk Factor Two-Township Study in Taiwan. (8902310)
1996
42
The emergence of clinically abnormal levels of cardiovascular disease risk factor variables among young adults: the Bogalusa Heart Study. (8610086)
1995
43
Who participates in cardiovascular disease risk factor screenings? Experience with a religious organization-based program. (8279596)
1994
44
Blood pressure and other cardiovascular disease risk factors in black adults with sickle cell trait or glucose-6-phosphate dehydrogenase deficiency. (2369999)
1990
45
Measurement error and reliability in four pediatric cross-sectional surveys of cardiovascular disease risk factor variables--the Bogalusa Heart Study. (3492509)
1987
46
Characteristics of participants and nonparticipants in a community cardiovascular disease risk factor screening: the Minnesota Heart Health Program. (3453156)
1986
47
Cardiovascular disease risk factor variables during the first year of life. (495597)
1979
48
Cardiovascular disease risk factor variables in children at two successive years--the Bogalusa heart study. (218982)
1979
49
Serum high density lipoprotein and its relationship to cardiovascular disease risk factor variables in children--the Bogalusa heart study. (218070)
1979
50
Dietary studies and the relationship of diet to cardiovascular disease risk factor variables in 10-year-old children--The Bogalusa Heart Study. (623054)
1978

Variations for Cardiovascular Disease Risk Factor

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Expression for genes affiliated with Cardiovascular Disease Risk Factor

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cardiovascular Disease Risk Factor

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Pathways for genes affiliated with Cardiovascular Disease Risk Factor

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51PathCards, 56Reactome
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Compounds for genes affiliated with Cardiovascular Disease Risk Factor

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Sources:
46Novoseek, 52PharmGKB, 12DrugBank, 62Tocris Bioscience, 30IUPHAR, 25HMDB, 3BitterDB
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Compounds related to Cardiovascular Disease Risk Factor according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1quinapril46 52 1212.1AGTR1, SELE
2furosemide46 62 30 52 25 1215.0SLC22A11, AGTR1
3carvedilol46 52 30 1213.0AGTR1, SELE
48-isoprostane4610.0AGTR1, SELE
5fluvastatin46 52 30 1212.9AGTR1, SELE
6cimetidine46 30 1211.9SELE, SLC22A11
7polymyxin b469.8SELE, CAMP
8lipoteichoic acid469.8CAMP, SELE
9iloprost62 30 46 1212.8CAMP, SELE
10losartan46 52 30 1212.8AGTR1, SELE
11rolipram46 62 3011.8SELE, CAMP
12pravastatin46 52 30 25 1213.7AGTR1, SLC22A11, SELE
13uric acid46 2510.6AGTR1, GCKR
14isoproterenol46 1210.5SELE, CAMP, AGTR1
15prostacyclin469.5AGTR1, CAMP, SELE
16estradiol46 25 1211.5AGTR1, SLC22A11, CAMP
17actinomycin d469.4SELE, CAMP, AGTR1
1825-hydroxyvitamin d469.4FGF23, CAMP
19sodium46 2510.4CAMP, SLC17A1, AGTR1
20histamine46 30 2511.2FCGR2B, SELE, CAMP
21vitamin d469.1CAMP, AGTR1, FGF23
221,25 dihydroxy vitamin d3469.0CAMP, FGF23
23creatinine469.0FGF23, AGTR1, SELE
24genistein46 30 62 3 25 1213.9AGTR1, CAMP, SELE, FCGR2B
25cholesterol46 30 25 1211.9AGTR1, CAMP, SELE
26heparin46 30 25 1211.7SELE, CAMP, AGTR1, FGF23
27lipid468.4FCGR2B, SELE, CAMP, GCKR, AGTR1
28tyrosine468.2FGF23, AGTR1, CAMP, FCGR2B
29serine468.1FCGR2B, SELE, CAMP, AGTR1, FGF23

GO Terms for genes affiliated with Cardiovascular Disease Risk Factor

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17Gene Ontology
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Biological processes related to Cardiovascular Disease Risk Factor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1calcium-mediated signalingGO:0197229.6AGTR1, SELE
2regulation of inflammatory responseGO:0507279.4SELE, AGTR1
3urate metabolic processGO:0464159.2SLC22A11, SLC17A1, GCKR
4transmembrane transportGO:0550859.2SLC22A11, SLC17A1, GCKR

Molecular functions related to Cardiovascular Disease Risk Factor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.3AGTR1, SLC22A11, GCKR, CAMP, STX16, SELE

Products for genes affiliated with Cardiovascular Disease Risk Factor

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cardiovascular Disease Risk Factor

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet