MCID: CRT004
MIFTS: 45

Carotid Artery Thrombosis malady

Blood diseases category

Summaries for Carotid Artery Thrombosis

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MalaCards based summary: Carotid Artery Thrombosis is related to myocardial infarction and head injury. An important gene associated with Carotid Artery Thrombosis is F3 (coagulation factor III (thromboplastin, tissue factor)), and among its related pathways are TGF Beta Signaling Pathway and Collagen biosynthesis and modifying enzymes. The compounds dabigatran and efegatran have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and endothelial, and related mouse phenotypes are tumorigenesis and vision/eye.

Aliases & Classifications for Carotid Artery Thrombosis

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Sources:
10Disease Ontology, 45Novoseek, 62UMLS, 57SNOMED-CT, 35MeSH
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Carotid Artery Thrombosis, Aliases & Descriptions:

Name: Carotid Artery Thrombosis 10 45 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood diseases


External Ids:

Disease Ontology10 DOID:3410
SNOMED-CT57 195181000, 86003009
MeSH35 D002341

Related Diseases for Carotid Artery Thrombosis

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Diseases related to Carotid Artery Thrombosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 93)
idRelated DiseaseScoreTop Affiliating Genes
1myocardial infarction30.2NOS3, COG2, F3, SERPINC1, F10, SERPINE1
2head injury10.4
3aspergillosis10.2
4myelitis10.2
5pharyngitis10.2
6rubella10.2
7neuronitis10.2
8horner's syndrome10.2
9cerebritis10.2
10encephalitis10.2
11endophthalmitis10.2
12nephrotic syndrome10.2
13neuritis10.2
14optic neuritis10.2
15carotidynia10.2
16headache10.2
17endotheliitis10.2
18sagittal sinus thrombosis10.0SERPINC1
19dysfibrinogenemia10.0SERPINC1
20meningococcemia10.0SERPINC1
21placental abruption10.0SERPINC1
22purpura10.0SERPINC1
23eclampsia10.0SERPINC1
24thrombotic thrombocytopenic purpura, acquired10.0SERPINE1, F3
25factor x deficiency10.0F3, F10
26hemarthrosis10.0F10, F3
27afibrinogenemia10.0F3, F10
28hemophilia b10.0F10, F3
29glanzmann thrombasthenia10.0F10, F3
30glucose intolerance10.0SERPINE1, COG2
31intracranial thrombosis10.0SERPINC1, F3
32blood platelet disease10.0F3, SERPINC1
33factor xii deficiency10.0F3, SERPINC1
34budd-chiari syndrome10.0SERPINC1, SERPINE1
35severe pre-eclampsia10.0SERPINE1, SERPINC1
36hellp syndrome10.0SERPINE1, SERPINC1
37leukopenia10.0CSF2, F3
38protein c deficiency10.0SERPINE1, SERPINC1
39pregnancy loss, recurrent 110.0F3, SERPINC1
40respiratory failure10.0F3, SERPINC1
41thrombophilia due to antithrombin iii deficiency10.0SERPINC1, F10
42hypertriglyceridemia10.0SERPINE1, COG2
43chronic granulomatous disease10.0IFNG, CSF2
44pulmonary sarcoidosis10.0IFNG, CSF2
45galactosemia10.0SERPINC1, F3
46factor vii deficiency10.0CSF2, IFNG
47aplastic anemia10.0IFNG, CSF2
48brain disease10.0F3, SERPINC1
49primary hyperoxaluria10.0COG2, F10, F3
50familial hyperlipidemia10.0COG2, SERPINE1

Graphical network of the top 20 diseases related to Carotid Artery Thrombosis:



Diseases related to carotid artery thrombosis

Symptoms for Carotid Artery Thrombosis

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Drugs & Therapeutics for Carotid Artery Thrombosis

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Drug clinical trials:

Search ClinicalTrials for Carotid Artery Thrombosis

Search NIH Clinical Center for Carotid Artery Thrombosis

Genetic Tests for Carotid Artery Thrombosis

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Anatomical Context for Carotid Artery Thrombosis

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MalaCards organs/tissues related to Carotid Artery Thrombosis:

33
Brain, Liver, Endothelial

Animal Models for Carotid Artery Thrombosis or affiliated genes

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Publications for Carotid Artery Thrombosis

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Articles related to Carotid Artery Thrombosis:

(show top 50)    (show all 112)
idTitleAuthorsYear
1
Direct penetrating and indirect neck trauma as a cause of internal carotid artery thrombosis and secondary ischemic stroke. (24748050)
2014
2
Symptomatic internal carotid artery thrombosis in acute carbon monoxide intoxication. (24388067)
2013
3
Spontaneous free floating carotid artery thrombosis. (23749854)
2013
4
Asymptomatic external carotid artery thrombosis in acute stroke. (22549811)
2012
5
Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody. (21479193)
2011
6
Internal carotid artery thrombosis after blunt trauma--salvage therapy with the penumbra thrombectomy system. (20349674)
2010
7
Effect of Chinese herbal medicine for activating blood circulation and detoxifying on expression of inflammatory reaction and tissue damage related factors in experimental carotid artery thrombosis rats. (20694780)
2010
8
Carotid artery thrombosis and delayed stroke associated with the use of a shoulder belt in a teenager. (19635289)
2009
9
Images from headache: cluster-like headache associated with intra-cavernous carotid artery thrombosis. (18808501)
2008
10
Acute carotid artery thrombosis: description of 12 surgically treated cases. (15714361)
2005
11
Prevention of carotid artery thrombosis after oral administration of the glycoprotein IIb/IIIa antagonist CRL42796. (12827029)
2003
12
Images in clinical medicine. Carotid-artery thrombosis secondary to basal skull fracture. (12890856)
2003
13
Accelerated thrombolysis in a rabbit model of carotid artery thrombosis with liposome-encapsulated and microencapsulated streptokinase. (12876627)
2003
14
Endothelial nitric oxide synthase pathophysiology after nonocclusive common carotid artery thrombosis in rats. (11973434)
2002
15
Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis. (10688985)
2000
16
Delayed bilateral internal carotid artery thrombosis following accidental strangulation. (10823110)
2000
17
Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis. (10991981)
2000
18
Internal carotid artery thrombosis and Horner's syndrome as complications of parapharyngeal abscess. (10388902)
1999
19
Traumatic internal carotid artery thrombosis after impalement injury. (9419147)
1997
20
On-table diagnosis of incipient carotid artery thrombosis during carotid endarterectomy by transcranial Doppler scanning. (7913141)
1994
21
Acute carotid artery thrombosis after neck irradiation. (7933034)
1994
22
Prevention of experimental carotid artery thrombosis by applaggin. (8246155)
1993
23
Transient platelet accumulation in the rat brain after common carotid artery thrombosis. An 111In-labeled platelet study. (8378958)
1993
24
Computed tomographic diagnosis of radiation-induced internal carotid artery thrombosis. (8457126)
1993
25
Serotonin release into plasma during common carotid artery thrombosis in rats. (1595108)
1992
26
Antithrombotic effects of the prostacyclin analogue naxaprostene after oral and intraduodenal application in rabbit carotid artery thrombosis. (1632291)
1992
27
Bilateral carotid artery thrombosis. (2802134)
1989
28
Internal carotid artery thrombosis: a complication of closed craniocervical trauma. (2695572)
1989
29
Maternal death from carotid artery thrombosis associated with the syndrome of hemolysis, elevated liver function, and low platelets. (2730743)
1989
30
Internal carotid artery thrombosis. (3830003)
1987
31
Prevention of experimental carotid artery thrombosis by magnetic vectoring of aspirin. (2887851)
1987
32
Carotid artery thrombosis associated with lupus anticoagulant. (3929417)
1985
33
Internal carotid artery thrombosis following soft palate injuries: a case report and review of 16 cases. (6390042)
1984
34
Internal carotid artery thrombosis presenting as catatonic stupor - case report. (21847298)
1983
35
Carotid artery thrombosis after elective mandibular and maxillary osteotomies. (7271163)
1981
36
Bilateral internal carotid artery thrombosis after closed head injury. (726960)
1978
37
Internal carotid artery thrombosis associated with a fracture. (277641)
1978
38
Internal carotid artery thrombosis following head and neck surgery. (591782)
1977
39
Bilateral internal carotid artery thrombosis. Prognosis and risk factors. (1146502)
1975
40
Internal carotid artery thrombosis secondary to closed head injury. (5434376)
1970
41
Traumatic internal carotid artery thrombosis in a child. (5434377)
1970
42
The collateral circulation via the ophthalmic artery in internal carotid artery thrombosis. (5803592)
1969
43
A clinical and radiological analysis of 77 patients with internal carotid artery thrombosis. (5583230)
1967
44
Juvenile bilateral carotid artery thrombosis. (4170404)
1966
45
The problem of internal carotid artery thrombosis. (13573002)
1958
46
Internal carotid artery thrombosis. (13520075)
1958
47
Pulseless disease and carotid-artery thrombosis; surgical considerations. (13477371)
1957
48
Symposium on carotid artery thrombosis. (13404768)
1955-1957
49
Bilateral internal carotid artery thrombosis; a report of two cases. (13250164)
1955
50
Carotid artery thrombosis; report of eight cases due to trauma. (18864120)
1948

Variations for Carotid Artery Thrombosis

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Expression for genes affiliated with Carotid Artery Thrombosis

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Search GEO for disease gene expression data for Carotid Artery Thrombosis.

Pathways for genes affiliated with Carotid Artery Thrombosis

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Compounds for genes affiliated with Carotid Artery Thrombosis

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Compounds related to Carotid Artery Thrombosis according to GeneCards/GeneDecks:

(show top 50)    (show all 164)
idCompoundScoreTop Affiliating Genes
1dabigatran51 4510.6SERPINC1, F3, F10
2efegatran459.6F3, SERPINC1, F10
3ecarin459.6SERPINC1, F3, F10
4nadroparin45 1310.6F10, SERPINC1, F3
5spectrozyme459.6F10, SERPINC1, F3
6danaparoid459.6F10, F3, SERPINC1
7rivaroxaban45 1310.6SERPINC1, F10, F3
8ximelagatran45 1310.6SERPINC1, F10, F3
9organon459.6F10, SERPINC1, F3
10tinzaparin45 1310.6SERPINC1, F3, F10
11heparinoids459.6F10, F3, SERPINC1
12p-amino benzamidine459.6F10, SERPINC1, SERPINE1
13fondaparinux459.6F10, SERPINC1, F3
14tranexamic acid45 1310.6SERPINE1, SERPINC1, F3
15ancrod459.6SERPINC1, SERPINE1, F10
16bivalirudin45 1310.6F3, SERPINC1, F10
17argatroban45 1310.6F3, SERPINC1, F10
18ppack459.5SERPINC1, F10, F3
19protamine sulfate459.5F10, F3, SERPINC1
20epsilon aminocaproic acid459.5SERPINC1, F3, SERPINE1
21tirofiban45 1310.5F10, F3, SERPINC1
22fucoidan459.5SERPINC1, F3, SERPINE1
23ticlopidine45 1310.4CSF2, F3, SERPINC1
24n(g)-nitro-l-arginine methyl ester459.4F3, SERPINE1, NOS3
25abciximab45 1310.3SERPINC1, F10, F3
26coumarin45 3 51 2612.3F10, F3, SERPINC1
27hirudin459.3F10, SERPINC1, F3, SERPINE1
28protamine459.2F10, SERPINC1, SERPINE1, F3
29desmopressin45 61 30 1312.2F3, SERPINC1, SERPINE1
30aprotinin45 1310.2F3, SERPINC1, SERPINE1, F10
31nomegestrol acetate459.1NOS3, COG2, SERPINC1
32clopidogrel45 51 26 1312.0NOS3, SERPINC1, F3, F10
33nitroglycerin45 1310.0F3, NOS3, COG2
34fluorescein45 139.9F3, SERPINC1, F10
35cyclophosphamide45 51 1310.9NOS3, CSF2, F3, SERPINE1
36citrate458.9SERPINC1, NOS3, F3, F10
37cerivastatin51 45 30 1311.9COG2, SERPINE1, NOS3
38prostacyclin458.8F3, SERPINC1, SERPINE1, NOS3
39endotoxin458.7SERPINE1, CSF2, IFNG, F3
40fibrinogen458.7F10, SERPINE1, SERPINC1, F3, COG2
4115-deoxy-delta-12,14-prostaglandin j2458.6CSF2, NOS3, IFNG, SERPINE1
42homocysteine45 269.5SERPINC1, F3, COG2, NOS3, SERPINE1
43heparin45 30 26 1311.3CSF2, F10, SERPINE1, COG2, SERPINC1, F3
44cycloheximide458.2F10, IFNG, F3, SERPINE1, CSF2
45actinomycin d458.2IFNG, F3, SERPINE1, CSF2, NOS3
46sb 20358045 618.9IFNG, NOS3, F3, SERPINE1, CSF2, F10
47estrogen457.9F10, NOS3, CSF2, COG2, SERPINC1, SERPINE1
48simvastatin45 51 61 30 26 1312.8SERPINE1, F10, IFNG, F3, COG2, NOS3
49aspirin45 51 30 2610.7SERPINC1, NOS3, CSF2, COG2, F3, SERPINE1
50vegf457.4IFNG, CSF2, F3, SERPINC1, SERPINE1, F10

GO Terms for genes affiliated with Carotid Artery Thrombosis

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Cellular components related to Carotid Artery Thrombosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intrinsic component of external side of plasma membraneGO:00312339.6F10, F3
2extracellular regionGO:00055767.9F10, SERPINE1, SERPINC1, IFNG, CSF2
3extracellular spaceGO:00056157.7SERPINE1, SERPINC1, F3, IFNG, CSF2

Biological processes related to Carotid Artery Thrombosis according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1blood coagulation, extrinsic pathwayGO:00075989.7F3, F10
2positive regulation of protein kinase B signalingGO:00518979.7F3, F10
3positive regulation of interleukin-23 productionGO:00327479.3CSF2, IFNG
4negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:019020429.2NOS3, SERPINE1
5positive regulation of angiogenesisGO:00457669.0SERPINE1, F3, NOS3
6cellular response to lipopolysaccharideGO:00712228.9IFNG, SERPINE1, CSF2
7blood coagulationGO:00075968.4NOS3, F3, SERPINC1, SERPINE1, F10

Molecular functions related to Carotid Artery Thrombosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phospholipid bindingGO:00055439.7F3, F10
2protease bindingGO:00020209.1F3, SERPINC1, SERPINE1
3protein bindingGO:00055156.9F10, SERPINE1, SERPINC1, F3, COG2, CSF2

Products for genes affiliated with Carotid Artery Thrombosis

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Sources for Carotid Artery Thrombosis

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet