MCID: CRT004
MIFTS: 47

Carotid Artery Thrombosis malady

Cardiovascular diseases, Blood diseases categories
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Summaries for Carotid Artery Thrombosis

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MalaCards based summary: Carotid Artery Thrombosis is related to hypercholesterolemia and diabetes mellitus. An important gene associated with Carotid Artery Thrombosis is F3 (coagulation factor III (thromboplastin, tissue factor)), and among its related pathways are TGF Beta Signaling Pathway and Collagen biosynthesis and modifying enzymes. The compounds dabigatran and efegatran have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and endothelial, and related mouse phenotypes are tumorigenesis and vision/eye.

Aliases & Classifications for Carotid Artery Thrombosis

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Sources:
8Disease Ontology, 44Novoseek, 62UMLS, 34MeSH, 57SNOMED-CT
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Carotid Artery Thrombosis, Aliases & Descriptions:

Name: Carotid Artery Thrombosis 8 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases, Blood diseases


External Ids:

Disease Ontology8 DOID:3410
SNOMED-CT57 195181000, 86003009
MeSH34 D002341

Related Diseases for Carotid Artery Thrombosis

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Diseases related to Carotid Artery Thrombosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 97)
idRelated DiseaseScoreTop Affiliating Genes
1hypercholesterolemia29.9NOS3, F10, SERPINE1, COG2
2diabetes mellitus29.5F10, SERPINE1, COG2, SERPINC1, NOS3
3myocardial infarction29.3NOS3, COG2, F3, SERPINC1, F10, SERPINE1
4head injury10.4
5sagittal sinus thrombosis10.4SERPINC1
6dysfibrinogenemia10.4SERPINC1
7meningococcemia10.4SERPINC1
8placental abruption10.4SERPINC1
9purpura10.4SERPINC1
10eclampsia10.4SERPINC1
11thrombotic thrombocytopenic purpura, acquired10.3SERPINE1, F3
12factor x deficiency10.3F3, F10
13hemarthrosis10.3F10, F3
14afibrinogenemia10.3F3, F10
15hemophilia b10.3F10, F3
16glanzmann's thrombasthenia10.3F10, F3
17intracranial thrombosis10.2SERPINC1, F3
18glucose intolerance10.2SERPINE1, COG2
19blood platelet disease10.2F3, SERPINC1
20factor xii deficiency10.2F3, SERPINC1
21hepatic vein thrombosis10.2SERPINC1, SERPINE1
22severe pre-eclampsia10.2SERPINE1, SERPINC1
23hellp syndrome10.2SERPINE1, SERPINC1
24leukopenia10.2CSF2, F3
25protein c deficiency10.2SERPINE1, SERPINC1
26respiratory failure10.2F3, SERPINC1
27antithrombin iii deficiency10.2SERPINC1, F10
28familial hypercholesterolemia10.2
29type 1 diabetes mellitus10.2
30pharyngitis10.2
31myelitis10.2
32rubella10.2
33neuronitis10.2
34horner's syndrome10.2
35cerebritis10.2
36aspergillosis10.2
37encephalitis10.2
38endophthalmitis10.2
39nephrotic syndrome10.2
40neuritis10.2
41optic neuritis10.2
42carotidynia10.2
43headache10.2
44endotheliitis10.2
45chronic granulomatous disease10.2IFNG, CSF2
46pulmonary sarcoidosis10.2IFNG, CSF2
47galactosemia10.2SERPINC1, F3
48factor vii deficiency10.2CSF2, IFNG
49hypertriglyceridemia10.2SERPINE1, COG2
50aplastic anemia10.1IFNG, CSF2

Graphical network of the top 20 diseases related to Carotid Artery Thrombosis:



Diseases related to carotid artery thrombosis

Symptoms for Carotid Artery Thrombosis

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Drugs & Therapeutics for Carotid Artery Thrombosis

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Drug clinical trials:

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Search NIH Clinical Center for Carotid Artery Thrombosis

Genetic Tests for Carotid Artery Thrombosis

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Anatomical Context for Carotid Artery Thrombosis

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MalaCards organs/tissues related to Carotid Artery Thrombosis:

32
Brain, Liver, Endothelial

Animal Models for Carotid Artery Thrombosis or affiliated genes

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Publications for Carotid Artery Thrombosis

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Articles related to Carotid Artery Thrombosis:

(show top 50)    (show all 111)
idTitleAuthorsYear
1
Direct penetrating and indirect neck trauma as a cause of internal carotid artery thrombosis and secondary ischemic stroke. (24748050)
2014
2
Symptomatic internal carotid artery thrombosis in acute carbon monoxide intoxication. (24388067)
2013
3
Spontaneous free floating carotid artery thrombosis. (23749854)
2013
4
Asymptomatic external carotid artery thrombosis in acute stroke. (22549811)
2012
5
Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody. (21479193)
2011
6
Internal carotid artery thrombosis after blunt trauma--salvage therapy with the penumbra thrombectomy system. (20349674)
2010
7
Effect of Chinese herbal medicine for activating blood circulation and detoxifying on expression of inflammatory reaction and tissue damage related factors in experimental carotid artery thrombosis rats. (20694780)
2010
8
Carotid artery thrombosis and delayed stroke associated with the use of a shoulder belt in a teenager. (19635289)
2009
9
Images from headache: cluster-like headache associated with intra-cavernous carotid artery thrombosis. (18808501)
2008
10
Acute carotid artery thrombosis: description of 12 surgically treated cases. (15714361)
2005
11
Prevention of carotid artery thrombosis after oral administration of the glycoprotein IIb/IIIa antagonist CRL42796. (12827029)
2003
12
Images in clinical medicine. Carotid-artery thrombosis secondary to basal skull fracture. (12890856)
2003
13
Accelerated thrombolysis in a rabbit model of carotid artery thrombosis with liposome-encapsulated and microencapsulated streptokinase. (12876627)
2003
14
Endothelial nitric oxide synthase pathophysiology after nonocclusive common carotid artery thrombosis in rats. (11973434)
2002
15
Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis. (10688985)
2000
16
Delayed bilateral internal carotid artery thrombosis following accidental strangulation. (10823110)
2000
17
Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis. (10991981)
2000
18
Internal carotid artery thrombosis and Horner's syndrome as complications of parapharyngeal abscess. (10388902)
1999
19
Traumatic internal carotid artery thrombosis after impalement injury. (9419147)
1997
20
On-table diagnosis of incipient carotid artery thrombosis during carotid endarterectomy by transcranial Doppler scanning. (7913141)
1994
21
Acute carotid artery thrombosis after neck irradiation. (7933034)
1994
22
Prevention of experimental carotid artery thrombosis by applaggin. (8246155)
1993
23
Transient platelet accumulation in the rat brain after common carotid artery thrombosis. An 111In-labeled platelet study. (8378958)
1993
24
Computed tomographic diagnosis of radiation-induced internal carotid artery thrombosis. (8457126)
1993
25
Serotonin release into plasma during common carotid artery thrombosis in rats. (1595108)
1992
26
Antithrombotic effects of the prostacyclin analogue naxaprostene after oral and intraduodenal application in rabbit carotid artery thrombosis. (1632291)
1992
27
Bilateral carotid artery thrombosis. (2802134)
1989
28
Internal carotid artery thrombosis: a complication of closed craniocervical trauma. (2695572)
1989
29
Maternal death from carotid artery thrombosis associated with the syndrome of hemolysis, elevated liver function, and low platelets. (2730743)
1989
30
Internal carotid artery thrombosis. (3830003)
1987
31
Prevention of experimental carotid artery thrombosis by magnetic vectoring of aspirin. (2887851)
1987
32
Carotid artery thrombosis associated with lupus anticoagulant. (3929417)
1985
33
Internal carotid artery thrombosis following soft palate injuries: a case report and review of 16 cases. (6390042)
1984
34
Internal carotid artery thrombosis presenting as catatonic stupor - case report. (21847298)
1983
35
Carotid artery thrombosis after elective mandibular and maxillary osteotomies. (7271163)
1981
36
Bilateral internal carotid artery thrombosis after closed head injury. (726960)
1978
37
Internal carotid artery thrombosis associated with a fracture. (277641)
1978
38
Internal carotid artery thrombosis following head and neck surgery. (591782)
1977
39
Bilateral internal carotid artery thrombosis. Prognosis and risk factors. (1146502)
1975
40
Internal carotid artery thrombosis secondary to closed head injury. (5434376)
1970
41
Traumatic internal carotid artery thrombosis in a child. (5434377)
1970
42
The collateral circulation via the ophthalmic artery in internal carotid artery thrombosis. (5803592)
1969
43
A clinical and radiological analysis of 77 patients with internal carotid artery thrombosis. (5583230)
1967
44
Juvenile bilateral carotid artery thrombosis. (4170404)
1966
45
The problem of internal carotid artery thrombosis. (13573002)
1958
46
Internal carotid artery thrombosis. (13520075)
1958
47
Pulseless disease and carotid-artery thrombosis; surgical considerations. (13477371)
1957
48
Symposium on carotid artery thrombosis. (13404768)
1955-1957
49
Bilateral internal carotid artery thrombosis; a report of two cases. (13250164)
1955
50
Carotid artery thrombosis; report of eight cases due to trauma. (18864120)
1948

Variations for Carotid Artery Thrombosis

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Expression for genes affiliated with Carotid Artery Thrombosis

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Expression patterns in normal tissues for genes affiliated with Carotid Artery Thrombosis

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Pathways for genes affiliated with Carotid Artery Thrombosis

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Compounds for genes affiliated with Carotid Artery Thrombosis

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Compounds related to Carotid Artery Thrombosis according to GeneCards/GeneDecks:

(show top 50)    (show all 164)
idCompoundScoreTop Affiliating Genes
1dabigatran50 4410.6SERPINC1, F3, F10
2efegatran449.6F3, SERPINC1, F10
3ecarin449.6SERPINC1, F3, F10
4nadroparin44 1110.6F10, SERPINC1, F3
5spectrozyme449.6F10, SERPINC1, F3
6danaparoid449.6F10, F3, SERPINC1
7rivaroxaban44 1110.6SERPINC1, F10, F3
8ximelagatran44 1110.6SERPINC1, F10, F3
9organon449.6F10, SERPINC1, F3
10tinzaparin44 1110.6SERPINC1, F3, F10
11heparinoids449.6F10, F3, SERPINC1
12p-amino benzamidine449.6F10, SERPINC1, SERPINE1
13fondaparinux449.6F10, SERPINC1, F3
14tranexamic acid44 1110.6SERPINE1, SERPINC1, F3
15ancrod449.6SERPINC1, SERPINE1, F10
16bivalirudin44 1110.6F3, SERPINC1, F10
17argatroban44 1110.6F3, SERPINC1, F10
18ppack449.5SERPINC1, F10, F3
19protamine sulfate449.5F10, F3, SERPINC1
20epsilon aminocaproic acid449.5SERPINC1, F3, SERPINE1
21tirofiban44 1110.5F10, F3, SERPINC1
22fucoidan449.5SERPINC1, F3, SERPINE1
23ticlopidine44 1110.4CSF2, F3, SERPINC1
24n(g)-nitro-l-arginine methyl ester449.4F3, SERPINE1, NOS3
25abciximab44 1110.3SERPINC1, F10, F3
26coumarin44 2 50 2412.3F10, F3, SERPINC1
27hirudin449.3F10, SERPINC1, F3, SERPINE1
28protamine449.2F10, SERPINC1, SERPINE1, F3
29desmopressin44 61 28 1112.2F3, SERPINC1, SERPINE1
30aprotinin44 1110.2F3, SERPINC1, SERPINE1, F10
31nomegestrol acetate449.1NOS3, COG2, SERPINC1
32clopidogrel44 50 24 1112.0NOS3, SERPINC1, F3, F10
33nitroglycerin44 1110.0F3, NOS3, COG2
34fluorescein44 119.9F3, SERPINC1, F10
35cyclophosphamide44 50 1110.9NOS3, CSF2, F3, SERPINE1
36citrate448.9SERPINC1, NOS3, F3, F10
37cerivastatin50 44 28 1111.9COG2, SERPINE1, NOS3
38prostacyclin448.8F3, SERPINC1, SERPINE1, NOS3
39endotoxin448.7SERPINE1, CSF2, IFNG, F3
40fibrinogen448.7F10, SERPINE1, SERPINC1, F3, COG2
4115-deoxy-delta-12,14-prostaglandin j2448.6CSF2, NOS3, IFNG, SERPINE1
42homocysteine44 249.5SERPINC1, F3, COG2, NOS3, SERPINE1
43heparin44 28 24 1111.3CSF2, F10, SERPINE1, COG2, SERPINC1, F3
44cycloheximide448.2F10, IFNG, F3, SERPINE1, CSF2
45actinomycin d448.2IFNG, F3, SERPINE1, CSF2, NOS3
46sb 20358044 618.9IFNG, NOS3, F3, SERPINE1, CSF2, F10
47estrogen447.9F10, NOS3, CSF2, COG2, SERPINC1, SERPINE1
48simvastatin44 50 61 28 24 1112.8SERPINE1, F10, IFNG, F3, COG2, NOS3
49aspirin44 50 28 2410.7SERPINC1, NOS3, CSF2, COG2, F3, SERPINE1
50vegf447.4IFNG, CSF2, F3, SERPINC1, SERPINE1, F10

GO Terms for genes affiliated with Carotid Artery Thrombosis

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Cellular components related to Carotid Artery Thrombosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intrinsic component of external side of plasma membraneGO:0312339.6F3, F10
2extracellular regionGO:0055767.9CSF2, IFNG, SERPINC1, SERPINE1, F10
3extracellular spaceGO:0056157.7SERPINE1, SERPINC1, F3, IFNG, CSF2

Biological processes related to Carotid Artery Thrombosis according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1blood coagulation, extrinsic pathwayGO:0075989.7F10, F3
2positive regulation of protein kinase B signalingGO:0518979.7F3, F10
3positive regulation of interleukin-23 productionGO:0327479.3IFNG, CSF2
4negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:19020429.2NOS3, SERPINE1
5positive regulation of angiogenesisGO:0457669.0NOS3, F3, SERPINE1
6cellular response to lipopolysaccharideGO:0712228.9SERPINE1, IFNG, CSF2
7blood coagulationGO:0075968.4NOS3, F3, SERPINC1, SERPINE1, F10

Molecular functions related to Carotid Artery Thrombosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phospholipid bindingGO:0055439.7F3, F10
2protease bindingGO:0020209.1F3, SERPINC1, SERPINE1
3protein bindingGO:0055156.9F10, SERPINE1, SERPINC1, F3, COG2, CSF2

Products for genes affiliated with Carotid Artery Thrombosis

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Sources for Carotid Artery Thrombosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet