MCID: CRT004
MIFTS: 39

Carotid Artery Thrombosis malady

Blood diseases category

Aliases & Classifications for Carotid Artery Thrombosis

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Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 55SNOMED-CT, 33MeSH
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Carotid Artery Thrombosis, Aliases & Descriptions:

Name: Carotid Artery Thrombosis 9 43 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood diseases


External Ids:

Disease Ontology9 DOID:3410
SNOMED-CT55 195181000, 86003009
MeSH33 D002341

Summaries for Carotid Artery Thrombosis

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MalaCards based summary: Carotid Artery Thrombosis is related to myocardial infarction and head injury. An important gene associated with Carotid Artery Thrombosis is F3 (coagulation factor III (thromboplastin, tissue factor)), and among its related pathways are TGF Beta Signaling Pathway and Collagen biosynthesis and modifying enzymes. The compounds dabigatran and efegatran have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and endothelial, and related mouse phenotypes are tumorigenesis and vision/eye.

Related Diseases for Carotid Artery Thrombosis

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Diseases related to Carotid Artery Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 93)
idRelated DiseaseScoreTop Affiliating Genes
1myocardial infarction29.3F10, SERPINE1, SERPINC1, F3, COG2, NOS3
2head injury10.4
3sagittal sinus thrombosis10.4SERPINC1
4dysfibrinogenemia10.4SERPINC1
5meningococcemia10.4SERPINC1
6placental abruption10.4SERPINC1
7purpura10.4SERPINC1
8eclampsia10.4SERPINC1
9thrombotic thrombocytopenic purpura, acquired10.3SERPINE1, F3
10factor x deficiency10.3F10, F3
11hemarthrosis10.3F10, F3
12afibrinogenemia10.3F3, F10
13hemophilia b10.3F10, F3
14glanzmann thrombasthenia10.3F3, F10
15glucose intolerance10.2COG2, SERPINE1
16intracranial thrombosis10.2F3, SERPINC1
17blood platelet disease10.2SERPINC1, F3
18factor xii deficiency10.2SERPINC1, F3
19budd-chiari syndrome10.2SERPINE1, SERPINC1
20severe pre-eclampsia10.2SERPINE1, SERPINC1
21leukopenia10.2F3, CSF2
22hellp syndrome10.2SERPINE1, SERPINC1
23protein c deficiency10.2SERPINE1, SERPINC1
24pregnancy loss, recurrent 110.2F3, SERPINC1
25respiratory failure10.2F3, SERPINC1
26aspergillosis10.2
27myelitis10.2
28pharyngitis10.2
29rubella10.2
30neuronitis10.2
31horner's syndrome10.2
32cerebritis10.2
33encephalitis10.2
34endophthalmitis10.2
35nephrotic syndrome10.2
36neuritis10.2
37optic neuritis10.2
38carotidynia10.2
39headache10.2
40endotheliitis10.2
41thrombophilia due to antithrombin iii deficiency10.2SERPINC1, F10
42hypertriglyceridemia10.2COG2, SERPINE1
43chronic granulomatous disease10.2IFNG, CSF2
44pulmonary sarcoidosis10.2CSF2, IFNG
45galactosemia10.2F3, SERPINC1
46factor vii deficiency10.2CSF2, IFNG
47aplastic anemia10.1CSF2, IFNG
48primary hyperoxaluria10.1F10, F3, COG2
49familial hyperlipidemia10.1COG2, SERPINE1
50graft-versus-host disease, protection against10.1IFNG, CSF2

Graphical network of the top 20 diseases related to Carotid Artery Thrombosis:



Diseases related to carotid artery thrombosis

Symptoms for Carotid Artery Thrombosis

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Drugs & Therapeutics for Carotid Artery Thrombosis

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Drug clinical trials:

Search ClinicalTrials for Carotid Artery Thrombosis

Search NIH Clinical Center for Carotid Artery Thrombosis

Genetic Tests for Carotid Artery Thrombosis

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Anatomical Context for Carotid Artery Thrombosis

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MalaCards organs/tissues related to Carotid Artery Thrombosis:

31
Brain, Liver, Endothelial

Animal Models for Carotid Artery Thrombosis or affiliated genes

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Publications for Carotid Artery Thrombosis

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Articles related to Carotid Artery Thrombosis:

(show top 50)    (show all 112)
idTitleAuthorsYear
1
Direct penetrating and indirect neck trauma as a cause of internal carotid artery thrombosis and secondary ischemic stroke. (24748050)
2014
2
Symptomatic internal carotid artery thrombosis in acute carbon monoxide intoxication. (24388067)
2013
3
Spontaneous free floating carotid artery thrombosis. (23749854)
2013
4
Asymptomatic external carotid artery thrombosis in acute stroke. (22549811)
2012
5
Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody. (21479193)
2011
6
Internal carotid artery thrombosis after blunt trauma--salvage therapy with the penumbra thrombectomy system. (20349674)
2010
7
Effect of Chinese herbal medicine for activating blood circulation and detoxifying on expression of inflammatory reaction and tissue damage related factors in experimental carotid artery thrombosis rats. (20694780)
2010
8
Carotid artery thrombosis and delayed stroke associated with the use of a shoulder belt in a teenager. (19635289)
2009
9
Images from headache: cluster-like headache associated with intra-cavernous carotid artery thrombosis. (18808501)
2008
10
Acute carotid artery thrombosis: description of 12 surgically treated cases. (15714361)
2005
11
Prevention of carotid artery thrombosis after oral administration of the glycoprotein IIb/IIIa antagonist CRL42796. (12827029)
2003
12
Images in clinical medicine. Carotid-artery thrombosis secondary to basal skull fracture. (12890856)
2003
13
Accelerated thrombolysis in a rabbit model of carotid artery thrombosis with liposome-encapsulated and microencapsulated streptokinase. (12876627)
2003
14
Endothelial nitric oxide synthase pathophysiology after nonocclusive common carotid artery thrombosis in rats. (11973434)
2002
15
Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis. (10688985)
2000
16
Delayed bilateral internal carotid artery thrombosis following accidental strangulation. (10823110)
2000
17
Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis. (10991981)
2000
18
Internal carotid artery thrombosis and Horner's syndrome as complications of parapharyngeal abscess. (10388902)
1999
19
Traumatic internal carotid artery thrombosis after impalement injury. (9419147)
1997
20
On-table diagnosis of incipient carotid artery thrombosis during carotid endarterectomy by transcranial Doppler scanning. (7913141)
1994
21
Acute carotid artery thrombosis after neck irradiation. (7933034)
1994
22
Prevention of experimental carotid artery thrombosis by applaggin. (8246155)
1993
23
Transient platelet accumulation in the rat brain after common carotid artery thrombosis. An 111In-labeled platelet study. (8378958)
1993
24
Computed tomographic diagnosis of radiation-induced internal carotid artery thrombosis. (8457126)
1993
25
Serotonin release into plasma during common carotid artery thrombosis in rats. (1595108)
1992
26
Antithrombotic effects of the prostacyclin analogue naxaprostene after oral and intraduodenal application in rabbit carotid artery thrombosis. (1632291)
1992
27
Bilateral carotid artery thrombosis. (2802134)
1989
28
Internal carotid artery thrombosis: a complication of closed craniocervical trauma. (2695572)
1989
29
Maternal death from carotid artery thrombosis associated with the syndrome of hemolysis, elevated liver function, and low platelets. (2730743)
1989
30
Internal carotid artery thrombosis. (3830003)
1987
31
Prevention of experimental carotid artery thrombosis by magnetic vectoring of aspirin. (2887851)
1987
32
Carotid artery thrombosis associated with lupus anticoagulant. (3929417)
1985
33
Internal carotid artery thrombosis following soft palate injuries: a case report and review of 16 cases. (6390042)
1984
34
Internal carotid artery thrombosis presenting as catatonic stupor - case report. (21847298)
1983
35
Carotid artery thrombosis after elective mandibular and maxillary osteotomies. (7271163)
1981
36
Bilateral internal carotid artery thrombosis after closed head injury. (726960)
1978
37
Internal carotid artery thrombosis associated with a fracture. (277641)
1978
38
Internal carotid artery thrombosis following head and neck surgery. (591782)
1977
39
Bilateral internal carotid artery thrombosis. Prognosis and risk factors. (1146502)
1975
40
Internal carotid artery thrombosis secondary to closed head injury. (5434376)
1970
41
Traumatic internal carotid artery thrombosis in a child. (5434377)
1970
42
The collateral circulation via the ophthalmic artery in internal carotid artery thrombosis. (5803592)
1969
43
A clinical and radiological analysis of 77 patients with internal carotid artery thrombosis. (5583230)
1967
44
Juvenile bilateral carotid artery thrombosis. (4170404)
1966
45
The problem of internal carotid artery thrombosis. (13573002)
1958
46
Internal carotid artery thrombosis. (13520075)
1958
47
Pulseless disease and carotid-artery thrombosis; surgical considerations. (13477371)
1957
48
Symposium on carotid artery thrombosis. (13404768)
1955-1957
49
Bilateral internal carotid artery thrombosis; a report of two cases. (13250164)
1955
50
Carotid artery thrombosis; report of eight cases due to trauma. (18864120)
1948

Variations for Carotid Artery Thrombosis

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Expression for genes affiliated with Carotid Artery Thrombosis

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Search GEO for disease gene expression data for Carotid Artery Thrombosis.

Pathways for genes affiliated with Carotid Artery Thrombosis

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Compounds for genes affiliated with Carotid Artery Thrombosis

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Compounds related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 164)
idCompoundScoreTop Affiliating Genes
1dabigatran49 4310.6SERPINC1, F3, F10
2efegatran439.6F3, SERPINC1, F10
3ecarin439.6SERPINC1, F3, F10
4nadroparin43 1210.6F10, SERPINC1, F3
5spectrozyme439.6F10, SERPINC1, F3
6danaparoid439.6F10, F3, SERPINC1
7rivaroxaban43 1210.6SERPINC1, F10, F3
8ximelagatran43 1210.6SERPINC1, F10, F3
9organon439.6F10, SERPINC1, F3
10tinzaparin43 1210.6SERPINC1, F3, F10
11heparinoids439.6F10, F3, SERPINC1
12p-amino benzamidine439.6F10, SERPINC1, SERPINE1
13fondaparinux439.6F10, SERPINC1, F3
14tranexamic acid43 1210.6SERPINE1, SERPINC1, F3
15ancrod439.6SERPINC1, SERPINE1, F10
16bivalirudin43 1210.6F3, SERPINC1, F10
17argatroban43 1210.6F3, SERPINC1, F10
18ppack439.5SERPINC1, F10, F3
19protamine sulfate439.5F10, F3, SERPINC1
20epsilon aminocaproic acid439.5SERPINC1, F3, SERPINE1
21tirofiban43 1210.5F10, F3, SERPINC1
22fucoidan439.5SERPINC1, F3, SERPINE1
23ticlopidine43 1210.4CSF2, F3, SERPINC1
24n(g)-nitro-l-arginine methyl ester439.4F3, SERPINE1, NOS3
25abciximab43 1210.3SERPINC1, F10, F3
26coumarin43 2 49 2412.3F10, F3, SERPINC1
27hirudin439.3F10, SERPINC1, F3, SERPINE1
28protamine439.2F10, SERPINC1, SERPINE1, F3
29desmopressin43 59 28 1212.2F3, SERPINC1, SERPINE1
30aprotinin43 1210.2F3, SERPINC1, SERPINE1, F10
31nomegestrol acetate439.1NOS3, COG2, SERPINC1
32clopidogrel43 49 24 1212.0NOS3, SERPINC1, F3, F10
33nitroglycerin43 1210.0F3, NOS3, COG2
34fluorescein43 129.9F3, SERPINC1, F10
35cyclophosphamide43 49 1210.9NOS3, CSF2, F3, SERPINE1
36citrate438.9SERPINC1, NOS3, F3, F10
37cerivastatin49 43 28 1211.9COG2, SERPINE1, NOS3
38prostacyclin438.8F3, SERPINC1, SERPINE1, NOS3
39endotoxin438.7SERPINE1, CSF2, IFNG, F3
40fibrinogen438.7F10, SERPINE1, SERPINC1, F3, COG2
4115-deoxy-delta-12,14-prostaglandin j2438.6CSF2, NOS3, IFNG, SERPINE1
42homocysteine43 249.5SERPINC1, F3, COG2, NOS3, SERPINE1
43heparin43 28 24 1211.3CSF2, F10, SERPINE1, COG2, SERPINC1, F3
44cycloheximide438.2F10, IFNG, F3, SERPINE1, CSF2
45actinomycin d438.2IFNG, F3, SERPINE1, CSF2, NOS3
46sb 20358043 598.9IFNG, NOS3, F3, SERPINE1, CSF2, F10
47estrogen437.9F10, NOS3, CSF2, COG2, SERPINC1, SERPINE1
48simvastatin43 49 59 28 24 1212.8SERPINE1, F10, IFNG, F3, COG2, NOS3
49aspirin43 49 28 2410.7SERPINC1, NOS3, CSF2, COG2, F3, SERPINE1
50vegf437.4IFNG, CSF2, F3, SERPINC1, SERPINE1, F10

GO Terms for genes affiliated with Carotid Artery Thrombosis

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Cellular components related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intrinsic component of external side of plasma membraneGO:00312339.6F10, F3
2extracellular regionGO:00055767.9F10, SERPINE1, SERPINC1, IFNG, CSF2
3extracellular spaceGO:00056157.7SERPINE1, SERPINC1, F3, IFNG, CSF2

Biological processes related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1blood coagulation, extrinsic pathwayGO:00075989.7F3, F10
2positive regulation of protein kinase B signalingGO:00518979.7F3, F10
3positive regulation of interleukin-23 productionGO:00327479.3CSF2, IFNG
4negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:019020429.2NOS3, SERPINE1
5positive regulation of angiogenesisGO:00457669.0SERPINE1, F3, NOS3
6cellular response to lipopolysaccharideGO:00712228.9IFNG, SERPINE1, CSF2
7blood coagulationGO:00075968.4NOS3, F3, SERPINC1, SERPINE1, F10

Molecular functions related to Carotid Artery Thrombosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phospholipid bindingGO:00055439.7F3, F10
2protease bindingGO:00020209.1F3, SERPINC1, SERPINE1
3protein bindingGO:00055156.9F10, SERPINE1, SERPINC1, F3, COG2, CSF2

Products for genes affiliated with Carotid Artery Thrombosis

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Sources for Carotid Artery Thrombosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet