CBT
MCID: CRT025
MIFTS: 37

Carotid Body Tumor (CBT) malady

Cancer category

Summaries for Carotid Body Tumor

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 A paraganglioma is rare neuroendocrine neoplasm that may develop at various body sites (including the... more...

MalaCards: Carotid Body Tumor, also known as carotid body paraganglioma, is related to paraganglioma and pheochromocytoma. An important gene associated with Carotid Body Tumor is SDHD (succinate dehydrogenase complex, subunit D, integral membrane protein), and among its related pathways are IL-6 Signaling Pathway and ErbB signaling pathway. The compounds mibg and catecholamine have been mentioned in the context of this disorder. Affiliated tissues include lymph node, brain and heart.

Aliases & Classifications for Carotid Body Tumor

Sources:
43NIH Rare Diseases, 45Novoseek, 61UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer


Aliases & Descriptions:

carotid body tumor 43 45
carotid body paraganglioma 43 61
carotid body tumors 43
cbt 43


Related Diseases for Carotid Body Tumor

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Carotid Body Tumor:



Diseases related to carotid body tumor

Clinical Features for Carotid Body Tumor

Drugs & Therapeutics for Carotid Body Tumor

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Carotid Body Tumor

Drug clinical trials:

Search ClinicalTrials for Carotid Body Tumor

Search NIH Clinical Center for Carotid Body Tumor

Search CenterWatch for Carotid Body Tumor

Genetic Tests for Carotid Body Tumor

Anatomical Context for Carotid Body Tumor

Sources:
33MalaCards
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MalaCards organs/tissues related to Carotid Body Tumor:

33
Lymph node, Brain, Heart, Liver, Thyroid, Salivary gland, B cells, Trachea

Animal Models for Carotid Body Tumor or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Carotid Body Tumor

Sources:
51PubMed
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Articles related to Carotid Body Tumor:

(show top 50)    (show all 225)
idTitleAuthorsYear
1
Ischemic optic neuropathy after carotid body tumor resection. (24336037)
2014
2
Cavernous arteriovenous fistula after the removal of carotid body tumor. (23261275)
2013
3
Embolic stroke after carotid artery ligation during carotid body tumor resection. (22101857)
2013
4
Hepatic metastasis of a carotid body paraganglioma 5 years after resection of the primary tumor. (23635567)
2013
5
Anesthetic management of schwannoma mimicking carotid body tumor. (23754924)
2012
6
Paradoxical embolus to the brain from embolization of a carotid body tumor. (21990509)
2012
7
Hypoglossal schwannoma masquerading as a carotid body tumor. (23213586)
2012
8
Case of spontaneous regression of carotid body tumor in a SDHD mutant: a discussion on potential mechanisms based on a review of the literature. (23083338)
2012
9
Preoperative embolization of carotid body tumor by direct percutaneous intratumoral injection of N-butyl cyanoacrylate glue assisted with balloon protection technique. (21354087)
2011
10
Preoperative angiography and transarterial embolization in the management of carotid body tumor: a single-center, 10-year experience. (20881559)
2010
11
Carotid body tumor. (23133303)
2010
12
Fever as the main presenting symptom of a carotid body tumor. (18298303)
2008
13
Bilateral carotid body tumor: the role of fine-needle aspiration biopsy in the preoperative diagnosis. (18232000)
2008
14
"Malignant" baroreflex failure after surgical resection of carotid body tumor. (17395286)
2007
15
Carotid body tumor: review of the literature and report of a case with a rare sensorineural symptomatology. (17577510)
2007
16
Accessory thyroid gland at carotid bifurcation presenting as a carotid body tumor: case report and review of the literature. (14718850)
2004
17
Malignant carotid body tumor: a case report. (16027492)
2004
18
Carotid body tumor (paraganglioma). (15266868)
2004
19
Baroreflex and chemoreflex function after bilateral carotid body tumor resection. (12640254)
2003
20
Imaging features of a presumed carotid body tumor in a dog. (12816376)
2003
21
Vascular leiomyoma of the carotid sheath simulating a carotid body tumor. (9550446)
1998
22
Oncogene expression in carotid body tumors. (8640709)
1996
23
The safe and complete removal of a carotid body tumor with elements suggestive of a malignant potential by employing an intraluminal shunt: report of a case. (7772919)
1995
24
Postoperative carotid body tumor evaluation: analysis using MR angiography. (7603283)
1995
25
Management of the internal carotid artery during carotid body tumor surgery. (7877408)
1995
26
Carotid body tumor associated with hyperparathyroidism. (7865400)
1994
27
Carotid body tumor. (1642539)
1992
28
Carotid body tumor: appearance on color-flow Doppler sonography. (1950148)
1991
29
Pulsed Doppler-ultrasonic diagnosis of carotid body tumor. (2691940)
1989
30
A multidisciplinary approach to reducing morbidity and operative blood loss during resection of carotid body tumor. (2911794)
1989
31
Carotid body tumor: familial occurrence. (3725108)
1986
32
Carotid body tumor: report of a case. (3463700)
1986
33
Total internal carotid artery occlusion by a benign carotid body tumor: a rare occurrence. (4017612)
1985
34
Maffucci's syndrome complicated by an intracranial chondrosarcoma and a carotid body tumor. Case report. (7264742)
1981
35
Cyanotic heart disease: "low altitude" risk for carotid body tumor? (625092)
1978
36
Carotid body tumor (chemodectoma). (4338958)
1972
37
Malignant carotid body tumor with extradural metastases. (5424534)
1970
38
A metastasizing carotid-body tumor. (5440014)
1970
39
Carotid body tumor. (5452879)
1970
40
The carotid body tumor. (5649728)
1968
41
Surgical management of carotid body tumor. (6053959)
1967
42
CAROTID BODY TUMOR. REPORT OF A CASE. (14113290)
1964
43
CAROTID BODY TUMOR. (14181183)
1964
44
CAROTID BODY TUMOR PRESENTING IN THE OROPHARYNX. (14245618)
1964
45
Carotid body tumor, its recognition, resection, and replacement by arterial graft. (13890290)
1962
46
The carotid body tumor in dogs. (13549300)
1958
47
Carotid body tumor of the trachea: glomus jugularis tumor, tympanic body tumor, nonchromaffin paraganglioma. (13403552)
1956
48
Glomus jugularis tumor of the middle ear; carotid body tumor, tympanic body tumor, nonchromaffin paraganglioma. (13157101)
1952
49
Bilateral carotid body tumor. (18122207)
1949
50
Roentgen manifestations in the skull of metastatic carotid body tumor (paraganglioma) of meningeoma and of mucocele; a report of three unusual cases. (20295660)
1947

Genetic Variations for Carotid Body Tumor

Expression for genes affiliated with Carotid Body Tumor

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Carotid Body Tumor

Search GEO for disease gene expression data for Carotid Body Tumor.

Pathways for genes affiliated with Carotid Body Tumor

Sources:
38NCBI BioSystems Database, 30KEGG, 50PharmGKB, 52QIAGEN, 54Reactome, 12EMD Millipore
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Compounds for genes affiliated with Carotid Body Tumor

Sources:
45Novoseek, 11DrugBank, 29IUPHAR, 24HMDB
See all sources

Compounds related to Carotid Body Tumor according to GeneCards/GeneDecks:

(show all 13)
idCompoundScoreTop Affiliating Genes
1mibg459.5SDHB, SDHD
2catecholamine459.4SDHB, SDHD
3UBIQUINONE-1119.1SDHD, SDHB, SDHC
42-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol119.1SDHD, SDHB, SDHC
5fumarate45 1110.1SDHC, SDHB, SDHD
6succinic acid29 11 2411.1SDHC, SDHB, SDHD
7iron-sulfur459.1SDHD, SDHC, SDHB
8ubiquinone459.1SDHD, SDHB, SDHC
9succinate459.0SDHD, SDHB, SDHC
10ag 1478458.8ERBB3, JUN
11iron45 249.8SDHC, SDHB, SDHD
12oxygen45 249.4SDHC, SDHB, SDHD, JUN
13vegf458.1SDHB, ERBB3, JUN, SDHC

GO Terms for genes affiliated with Carotid Body Tumor

Sources:
16Gene Ontology
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Cellular components related to Carotid Body Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial inner membraneGO:0057438.9SDHC, SDHB, SDHD
2mitochondrial respiratory chain complex IIGO:0057498.6SDHC, SDHB, SDHD

Biological processes related to Carotid Body Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of neuron apoptotic processGO:0435249.1ERBB3, JUN
2aerobic respirationGO:0090609.0SDHB, SDHC
3tricarboxylic acid cycleGO:0060998.9SDHC, SDHB, SDHD
4respiratory electron transport chainGO:0229048.9SDHD, SDHB, SDHC
5cellular metabolic processGO:0442378.8SDHC, SDHB, SDHD

Molecular functions related to Carotid Body Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1heme bindingGO:0200379.5SDHC, SDHD
2ubiquinone bindingGO:0480399.3SDHB, SDHD
3electron carrier activityGO:0090558.6SDHC, SDHB, SDHD

Products for genes affiliated with Carotid Body Tumor

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Carotid Body Tumor

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet