Aliases & Classifications for Carotid Stenosis

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Aliases & Descriptions for Carotid Stenosis:

Name: Carotid Stenosis 8 10 44 61
Carotid Stenosis, Susceptibility to 9
 
Stenosis, Carotid Artery 8
Carotid Artery Stenosis 8


External Ids:

Disease Ontology8 DOID:13001
SNOMED-CT56 64586002, 195181000
MeSH33 D016893

Summaries for Carotid Stenosis

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Wikipedia:64 Carotid stenosis is a narrowing or constriction of the inner surface (lumen) of the carotid artery,... more...

MalaCards based summary: Carotid Stenosis, also known as carotid stenosis, susceptibility to, is related to hepatitis and abdominal aortic aneurysm. An important gene associated with Carotid Stenosis is HABP2 (hyaluronan binding protein 2), and among its related pathways are IL-3 Signaling Pathway and amb2 Integrin signaling. The compounds sele and lxa4 have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and bone, and related mouse phenotype homeostasis/metabolism.

Related Diseases for Carotid Stenosis

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Diseases related to Carotid Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 90)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis30.8PON1, SELP
2abdominal aortic aneurysm30.7MMP1, MMP9
3ischemia30.7SELP, PON1, FABP2
4coronary artery disease30.5PON1, SELP
5vascular disease30.4SELP, PON1, MMP9
6hyperhomocysteinemia30.4PON1, SELP
7cerebrovascular disease30.1SELP, PON1, FABP2
8breast cancer29.8MMP1, MMP9, HABP2
9atherosclerosis29.1HABP2, SELP, PON1, MMP9, MMP1, FABP2
10cerebritis10.8
11cervicitis10.5
12artery disease10.4
13intracranial aneurysm10.4
14aneurysm10.4
15arteriosclerosis10.4PON1
16atrial fibrillation10.4
17retinitis10.3
18aortic aneurysm10.3
19synovitis10.3MMP1
20thrombophilia due to thrombin defect10.3HABP2, SELP
21peripheral vascular disease10.3
22coronary stenosis10.3PON1, SELP
23antiphospholipid syndrome10.2PON1, SELP
24microvascular complications of diabetes 110.2SELP, MMP9
25hyperlipidemia, familial combined10.2FABP2, PON1
26neuronitis10.2
27carotid artery disease10.2
28cholesterol embolism10.2
29retinal artery occlusion10.2
30sleep apnea10.2
31autonomic dysfunction10.2
32blindness10.2
33tetralogy of fallot10.2
34moyamoya disease 210.2
35sinusitis10.2
36pituitary apoplexy10.2
37oral squamous cell carcinoma10.2
38aortitis10.2
39tracheal stenosis10.2
40subclavian steal syndrome10.2
41brain stem infarction10.2
42hepatic encephalopathy10.2
43kidney disease10.2
44mediastinitis10.2
45familial hyperlipidemia10.2PON1, SELP
46glucose intolerance10.1FABP2, PON1
47hypertriglyceridemia10.1FABP2, PON1
48conjunctivochalasis10.1MMP9, MMP1
49middle ear cholesteatoma10.1MMP1, MMP9
50pulmonary emphysema10.1MMP1, MMP9

Graphical network of the top 20 diseases related to Carotid Stenosis:



Diseases related to carotid stenosis

Symptoms for Carotid Stenosis

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Drugs & Therapeutics for Carotid Stenosis

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Drug clinical trials:

Search ClinicalTrials for Carotid Stenosis

Search NIH Clinical Center for Carotid Stenosis

Genetic Tests for Carotid Stenosis

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Anatomical Context for Carotid Stenosis

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MalaCards organs/tissues related to Carotid Stenosis:

31
Brain, Heart, Bone, Smooth muscle, Breast, T cells, Endothelial

Animal Models for Carotid Stenosis or affiliated genes

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MGI Mouse Phenotypes related to Carotid Stenosis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.1IL12A, FABP2, MMP1, MMP9, PON1, SELP

Publications for Carotid Stenosis

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Articles related to Carotid Stenosis:

(show top 50)    (show all 548)
idTitleAuthorsYear
1
Emergency stenting for acute symptomatic carotid stenosis: dissecting the evidence. (25720774)
2015
2
Revascularization of asymptomatic carotid stenosis is not appropriate in patients on dialysis. (25720927)
2015
3
Endovascular advances for extracranial carotid stenosis. (24402498)
2014
4
Long-term follow-up study of endarterectomy versus angioplasty in patients with symptomatic severe carotid stenosis trial. (25082808)
2014
5
Safety and effectiveness of emergency carotid artery stenting for a high-grade carotid stenosis with intraluminal thrombus under proximal flow control in hyperacute and acute stroke. (22170821)
2013
6
Treatment of symptomatic carotid stenosis: carotid stent placement versus endarterectomy. (23873312)
2013
7
The analysis of the connection between plaque morphology of asymptomatic carotid stenosis and ischemic brain lesions. (24397192)
2013
8
Reversal of ophthalmic artery flow and stroke outcomes in asian patients with acute ischemic stroke and unilateral severe cervical carotid stenosis. (24312492)
2013
9
Quantitative flow measurement by digital subtraction angiography in cerebral carotid stenosis using optical flow method. (23694912)
2013
10
A randomized trial of decision-making in asymptomatic carotid stenosis. (22218277)
2012
11
Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis. (22422912)
2012
12
Identifying high-risk asymptomatic carotid stenosis. (23480656)
2012
13
Carotid stenosis treatments compared. Both surgical and nonsurgical options can prevent stroke. (23437463)
2012
14
Impairments in cognitive function and brain connectivity in severe asymptomatic carotid stenosis. (22935402)
2012
15
Higher incidence of carotid stenosis in patients with central retinal artery occlusion. (20384592)
2011
16
Controversies in neurology: asymptomatic carotid stenosis--intervention or just stick to medical therapy. The argument for carotid endarterectomy. (21298296)
2011
17
Update on surgical management for asymptomatic carotid stenosis. (20922504)
2011
18
Asymptomatic carotid stenosis: screening and management. (21667597)
2011
19
Treatment strategies for carotid stenosis in patients at increased risk for surgery. (21722783)
2011
20
Short-term outcome after stenting versus endarterectomy for symptomatic carotid stenosis: a preplanned meta-analysis of individual patient data. (20832852)
2010
21
Inraoperative and Histological Visualization of Disrupted Vulnerable Plaques following Diagnostic Angiography of Moderate Carotid Stenosis. (20700419)
2010
22
Cerebral reserve is decreased in elderly patients with carotid stenosis. (20620003)
2010
23
Extracranial carotid stenosis and peripheral arterial disease in Thai patients with coronary artery disease. (20483809)
2010
24
Reproducibility of semi-automated measurement of carotid stenosis on CTA. (20724259)
2010
25
Stroke: Carotid stenosis--surgery or stenting to prevent stroke? (21131910)
2010
26
How should physicians practically approach symptomatic and asymptomatic carotid stenosis? (20726212)
2010
27
Cardiac surgery, carotid stenosis, and stroke prevention. (20469611)
2010
28
Central sleep apnea indicates autonomic dysfunction in asymptomatic carotid stenosis: a potential marker of cerebrovascular and cardiovascular risk. (20337190)
2010
29
Two cases of branch retinal arterial occlusion after carotid artery stenting in the carotid stenosis. (19337482)
2009
30
Prevalence of carotid stenosis in a high-risk Caribbean population. (19246696)
2009
31
Strokes after cardiac surgery and relationship to carotid stenosis. (19752298)
2009
32
Combined carotid stenting and urgent coronary artery surgery in unstable angina patients with severe carotid stenosis. (19416961)
2009
33
High risk of early neurological recurrence in symptomatic carotid stenosis. (19498196)
2009
34
High cardiovascular event rates in patients with asymptomatic carotid stenosis: the REACH Registry. (19473362)
2009
35
Does metabolic syndrome predict silent carotid stenosis in coronary patients? (18283528)
2008
36
Expression profiles in surgically-induced carotid stenosis: a combined transcriptomic and proteomic investigation. (19012726)
2008
37
Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis (EVA-3S) trial: results up to 4 years from a randomised, multicentre trial. (18774745)
2008
38
Dynamic cerebral autoregulation in carotid stenosis before and after carotid stenting. (18486427)
2008
39
How asymptomatic is asymptomatic carotid stenosis? (17581914)
2007
40
Current status of carotid endarterectomy and stenting for symptomatic carotid stenosis. (17971647)
2007
41
Severity of asymptomatic carotid stenosis and risk of ipsilateral hemispheric ischaemic events: results from the ACSRS study. Nicolaides et al.: EJVES 2005; 30: 275-284. (16359888)
2006
42
Accuracy of angiography and Doppler ultrasonography in the detection of carotid stenosis: a histopathological study of 123 cases. (16523222)
2006
43
Accurate, practical and cost-effective assessment of carotid stenosis in the UK. (16904049)
2006
44
Atherosclerotic carotid stenosis and occlusion. (17290125)
2006
45
Recurrent carotid stenosis after angioplasty and stenting. (15874940)
2005
46
Carotid plaque mast cells associate with atherogenic serum lipids, high grade carotid stenosis and symptomatic carotid artery disease. Results from the helsinki carotid endarterectomy study. (15775709)
2005
47
Commentary. Carotid angioplasty and stenting versus carotid endarterectomy for treatment of asymptomatic carotid stenosis: a randomized trial in a community hospital. (15952703)
2005
48
Carotid stenosis measurement on colour Doppler ultrasound: agreement of ECST, NASCET and CCA methods applied to ultrasound with intra-arterial angiographic stenosis measurement. (15964165)
2005
49
Adhesion molecule expression in symptomatic and asymptomatic carotid stenosis. (12821729)
2003
50
An angiotensin-converting enzyme gene polymorphism suggests a genetic distinction between ischaemic stroke and carotid stenosis. (10354208)
1999

Variations for Carotid Stenosis

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Expression for genes affiliated with Carotid Stenosis

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Search GEO for disease gene expression data for Carotid Stenosis.

Pathways for genes affiliated with Carotid Stenosis

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Pathways related to Carotid Stenosis according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5MMP9, SELP
29.5MMP9, SELP
39.5MMP9, SELP
4
Show member pathways
9.4SELP, MMP1
5
Show member pathways
Metalloproteases in connective tissue degradation
9.3MMP1, MMP9
6
Show member pathways
9.3MMP9, MMP1
79.3MMP1, MMP9
89.3MMP9, MMP1
99.3MMP1, MMP9
10
Show member pathways
fatty acid beta-oxidation VI (peroxisome)36
9.3FABP2, MMP1
119.2IL12A, SELP
129.2IL12A, SELP

Compounds for genes affiliated with Carotid Stenosis

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Compounds related to Carotid Stenosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idCompoundScoreTop Affiliating Genes
1sele4410.0PON1, SELP
2lxa4449.9MMP1, SELP
3clopidogrel44 50 24 1112.8PON1, SELP
4cgs-27023a449.8MMP1, MMP9
5prinomastat449.8MMP9, MMP1
6ilomastat449.8MMP1, MMP9
7cilomilast449.7MMP9, MMP1
88-isoprostane449.7PON1, MMP9
9candesartan44 50 28 1112.7MMP1, SELP
10latanoprost44 1110.7MMP1, MMP9
11(4-aminophenyl)mercuric acetate449.7MMP9, MMP1
12quinacrine44 1110.7MMP1, SELP
13gm 6001609.7MMP1, MMP9
14gi 254023x609.7MMP9, MMP1
15uk 383367609.7MMP1, MMP9
16geranylgeranyl pyrophosphate449.7MMP9, MMP1
17hydroxamate449.6MMP9, MMP1
18marimastat44 60 1111.6MMP1, MMP9
19zoledronic acid449.6MMP1, MMP9
201,10-phenanthroline44 110.5MMP9, MMP1
21ns 39844 6010.5MMP9, MMP1
22simvastatin44 50 60 28 24 1114.5PON1, SELP, MMP9
23batimastat44 60 1111.4MMP9, MMP1
24pravastatin44 50 28 24 1113.4MMP1, SELP, PON1
25dextran sulfate449.4HABP2, SELP
26aspirin44 50 28 2412.4SELP, MMP1, PON1
27hyaluronic acid44 2410.4HABP2, MMP9, MMP1
28aprotinin44 1110.4MMP9, SELP, MMP1
29hydroxyproline44 24 1111.3MMP9, MMP1
30formaldehyde44 2410.3MMP9, SELP, MMP1
31alpha tocopherol449.3MMP1, MMP9, PON1
32rantes449.3MMP9, SELP, MMP1
33rosiglitazone28 44 50 24 1113.3PON1, MMP1, MMP9
34epinephrine44 24 1111.3MMP1, MMP9, SELP
35n acetylcysteine449.3SELP, MMP9, MMP1
36norepinephrine44 24 1111.2MMP1, MMP9, SELP
37fibrinogen449.2SELP, PON1, MMP9, HABP2
38genistein44 28 60 1 24 1114.1SELP, MMP1, MMP9
39mycophenolate mofetil44 50 1111.1MMP1, SELP, IL12A
40fenofibrate44 50 1111.0PON1, FABP2, SELP, MMP9
41cyclosporin a44 28 6011.0SELP, MMP1, MMP9
42pge2448.9MMP9, MMP1, SELP
43fluvastatin44 50 28 1111.9MMP9, PON1, MMP1, SELP
44atorvastatin44 50 28 24 1112.9PON1, MMP1, SELP, MMP9
45lactate448.8MMP9, SELP, MMP1
46vitamin a44 24 1110.8FABP2, MMP1, PON1, MMP9
47estrogen448.8SELP, PON1, MMP1, MMP9
48retinoic acid44 249.7SELP, MMP9, MMP1, FABP2
49creatinine448.4PON1, MMP9, MMP1, FABP2, SELP
50cysteine448.4MMP1, MMP9, PON1, SELP, FABP2

GO Terms for genes affiliated with Carotid Stenosis

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Cellular components related to Carotid Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.5MMP1, MMP9, PON1, HABP2
2extracellular spaceGO:00056157.6IL12A, MMP9, PON1, SELP, HABP2

Biological processes related to Carotid Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to lipopolysaccharideGO:00324969.2IL12A, SELP
2collagen catabolic processGO:00305749.2MMP1, MMP9
3extracellular matrix disassemblyGO:00226179.0MMP1, MMP9
4leukocyte migrationGO:00509008.9MMP1, MMP9, SELP

Molecular functions related to Carotid Stenosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1metalloendopeptidase activityGO:00042229.3MMP1, MMP9

Sources for Carotid Stenosis

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet