MCID: CRT013
MIFTS: 36

Carotid Stenosis malady

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Carotid Stenosis

Aliases & Descriptions for Carotid Stenosis:

Name: Carotid Stenosis 12 52 42 14 69
Carotid Artery Stenosis 12 14
Carotid Stenosis, Susceptibility to 13
Stenosis, Carotid Artery 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13001
MeSH 42 D016893
NCIt 47 C95804
SNOMED-CT 64 195181000 64586002
UMLS 69 C0007282

Summaries for Carotid Stenosis

MalaCards based summary : Carotid Stenosis, also known as carotid artery stenosis, is related to moyamoya disease 2 and moyamoya 6 with achalasia. An important gene associated with Carotid Stenosis is HABP2 (Hyaluronan Binding Protein 2). The drugs Aspirin and Cilostazol have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and myeloid.

Wikipedia : 71 Carotid stenosis is a narrowing or constriction of the inner surface (lumen) of the carotid artery,... more...

Related Diseases for Carotid Stenosis

Graphical network of the top 20 diseases related to Carotid Stenosis:



Diseases related to Carotid Stenosis

Symptoms & Phenotypes for Carotid Stenosis

Drugs & Therapeutics for Carotid Stenosis

Drugs for Carotid Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 186)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
2
Cilostazol Approved Phase 4 73963-72-1 2754
3
Ticlopidine Approved Phase 4,Phase 3,Phase 2 55142-85-3 5472
4
Rosiglitazone Approved, Investigational Phase 4 122320-73-4 77999
5
Simvastatin Approved Phase 4,Phase 3 79902-63-9 54454
6
Acetaminophen Approved Phase 4 103-90-2 1983
7
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
8
Remifentanil Approved Phase 4 132875-61-7 60815
9
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
10
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
11
Prilocaine Approved Phase 4 721-50-6 4906
12
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
13
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
14
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
15
Losartan Approved Phase 4 114798-26-4 3961
16
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
17
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
18
Desflurane Approved Phase 4 57041-67-5 42113
19
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3,Phase 2 120202-66-6, 113665-84-2 60606
20
Niacin Approved, Investigational, Nutraceutical Phase 4 59-67-6 938
21
Nicotinamide Approved, Nutraceutical Phase 4 98-92-0 936
22
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
23
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
24 tannic acid Approved, Nutraceutical Phase 4,Phase 3
25 insulin Phase 4
26 Atorvastatin Calcium Phase 4,Phase 3,Phase 2 134523-03-8
27 Analgesics Phase 4,Phase 3,Phase 2
28 Adrenergic Agents Phase 4
29 Adrenergic Agonists Phase 4
30 Neuroprotective Agents Phase 4
31 Adrenergic alpha-Agonists Phase 4
32 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
33 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 2
34 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
35 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
36 Trace Elements Phase 4,Phase 2
37 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
38 Vasodilator Agents Phase 4,Phase 3,Phase 2
39 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 3,Phase 2
40 Anti-Asthmatic Agents Phase 4
41 Vitamins Phase 4,Phase 2
42 Phosphodiesterase 3 Inhibitors Phase 4
43 Phosphodiesterase Inhibitors Phase 4,Phase 2
44 Hypolipidemic Agents Phase 4,Phase 3,Phase 2
45 Platelet Aggregation Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
46 Fibrinolytic Agents Phase 4,Phase 2,Phase 3
47 Anticholesteremic Agents Phase 4,Phase 3,Phase 2
48 Protective Agents Phase 4,Phase 2
49 Insulin, Globin Zinc Phase 4
50 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 239)
id Name Status NCT ID Phase
1 Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis Unknown status NCT00772278 Phase 4
2 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting Unknown status NCT01572623 Phase 4
3 Early Warning and Optimization Strategy in Carotid Endarterectomy Unknown status NCT01210937 Phase 4
4 Carotid Artery Stenting With Cilostazol Addition for Restenosis Unknown status NCT01261234 Phase 4
5 Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery Completed NCT01146301 Phase 4
6 Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarterectomy Completed NCT02609087 Phase 4
7 Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study) Completed NCT00287508 Phase 4
8 A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease Completed NCT00178672 Phase 4
9 Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit Completed NCT01948505 Phase 4
10 Effect Of Rosiglitazone On Carotid Intima Media Thickness In Patients With Insulin Resistance Syndrome And/Or Type 2 Diabetes Completed NCT00306644 Phase 4
11 Carotid Atherosclerosis Regression at Magnetic Resonance Assessment. Completed NCT00307307 Phase 4
12 Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression Completed NCT01212900 Phase 4
13 Stop Atherosclerosis in Native Diabetics Study Completed NCT00147251 Phase 4
14 Melatonin in Patients Under Carotid Endarterectomy Recruiting NCT03115034 Phase 4
15 Ultrasound-guided Intermediate Cervical Plexus Block Recruiting NCT02794974 Phase 4
16 The Effect of the Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During TAVI Recruiting NCT01866800 Phase 4
17 Comparison of Staged Angioplasty and Routine Single-stage Stenting (CAS) in the Treatment of Carotid Artery Stenosis Not yet recruiting NCT02224209 Phase 4
18 High Dose Atorvastatin for Preventing Periprocedural Ischemic Brain Damage During Carotid Artery Stenting Not yet recruiting NCT03079115 Phase 4
19 Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis Terminated NCT00805311 Phase 4
20 Post-Approval Study of the NexStent Carotid Stent System and the FilterWire EZ Embolic Protection System: SONOMA Terminated NCT00478673 Phase 4
21 The Effects of DexMed and Desflurane on Carotid Patients Terminated NCT00335972 Phase 4
22 Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease Terminated NCT01236508 Phase 4
23 PROximal Protection VErsus NON-Protection in Carotid Artery Stenting Unknown status NCT01331473 Phase 3
24 EVA3S: Endarterectomy Versus Angioplasty in Patients With Severe Symptomatic Carotid Stenosis Completed NCT00190398 Phase 3
25 ViVEXX Carotid Revascularization Trial (VIVA) Completed NCT00417963 Phase 3
26 Carotid Artery Stenting With Protection Registry Completed NCT00318851 Phase 3
27 Progression of Carotid Artery Atheroma in Moderately Hypercholesterolemic Subjects Completed NCT00654394 Phase 3
28 Gadobutrol Enhanced MRA of the Supra-aortic Vessels Completed NCT01344447 Phase 3
29 GORE® Embolic Filter in Carotid Stenting for High Risk Surgical Subjects (EMBOLDEN) Completed NCT00766493 Phase 3
30 SONOlysis in Prevention of Brain Infarctions dUring Carotid Stenting and caroTid EndaRterectomy Completed NCT01591005 Phase 3
31 GORE Embolic Protection With Reverse Flow Completed NCT00594100 Phase 3
32 Coronary Angiography Before Elective Carotid Endarterectomy in Patients With Asymptomatic Coronary Artery Disease Completed NCT02260453 Phase 3
33 Carotid Revascularization With ev3 Arterial Technology Evolution (CREATE) Trial Completed NCT00619775 Phase 3
34 ACCULINK for Revascularization of Carotids in High Risk Patients "The ARCHeR Trial" Completed NCT00180518 Phase 2, Phase 3
35 Carotid With Bivalirudin Angioplasty Completed NCT00812383 Phase 2, Phase 3
36 Specific Lp(a) Apheresis for Regression of Coronary and Carotid Atherosclerosis Completed NCT02133807 Phase 3
37 Carotid Artery Revascularization Using the Boston Scientific EPI Filter Wire EZ™ and the EndoTex™ NexStent™ Completed NCT00600327 Phase 3
38 Stenting and Angioplasty With Protection in Patients at High Risk for Endarterectomy (SAPPHIRE) Completed NCT00231270 Phase 3
39 Clopidogrel Resistance and Embolism in Carotid Artery Stenting Recruiting NCT02133989 Phase 3
40 Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes Recruiting NCT02850081 Phase 3
41 The Carotid and Middle Cerebral Artery Occlusion Surgery Study Recruiting NCT01758614 Phase 3
42 Clear-Road Trial, Investigating the Efficacy of the RoadSaver Stent Active, not recruiting NCT02529345 Phase 2, Phase 3
43 The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms Active, not recruiting NCT01636453 Phase 3
44 " Endarterectomy Combined With Optimal Medical Therapy (OMT) vs OMT Alone in Patients With Asymptomatic Severe Atherosclerotic Carotid Artery Stenosis at Higher-than-average Risk of Ipsilateral Stroke " Not yet recruiting NCT02841098 Phase 3
45 Remote Ischemic Preconditioning for Carotid Endarterectomy Not yet recruiting NCT02808754 Phase 2, Phase 3
46 Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis Terminated NCT00126139 Phase 3
47 Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting Terminated NCT00395785 Phase 2, Phase 3
48 Medico-economic Evaluation of Preoperative Cerebral Oximetry Monitoring During Carotid Endarterectomy Terminated NCT01415648 Phase 3
49 Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I) Terminated NCT00106938 Phase 3
50 Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant Terminated NCT00228176 Phase 3

Search NIH Clinical Center for Carotid Stenosis

Cochrane evidence based reviews: carotid stenosis

Genetic Tests for Carotid Stenosis

Anatomical Context for Carotid Stenosis

MalaCards organs/tissues related to Carotid Stenosis:

39
Brain, Heart, Myeloid, T Cells, Smooth Muscle, Endothelial, Bone

Publications for Carotid Stenosis

Articles related to Carotid Stenosis:

(show top 50) (show all 627)
id Title Authors Year
1
Symptomatic carotid stenosis: is stenting as safe and effective as carotid endarterectomy? ( 28002121 )
2017
2
Which patients with asymptomatic carotid stenosis benefit from revascularization? ( 27875340 )
2017
3
Mild Carotid Stenosis with Recurrent Symptoms Triggered by Eating. ( 27989985 )
2017
4
Impact of Hypertriglyceridemia on Carotid Stenosis Progression under Normal Low-Density Lipoprotein Cholesterol Levels. ( 28495179 )
2017
5
Circulating MicroRNAs as Novel Biomarkers of Stenosis Progression in Asymptomatic Carotid Stenosis. ( 27899750 )
2017
6
Limb shaking: Video EEG report in a patient with neurolupus but no carotid stenosis. ( 27777345 )
2016
7
Gender differences in patients with carotid stenosis. ( 26986705 )
2016
8
Intervention versus Aggressive Medical Therapy for Cognition in Severe Asymptomatic Carotid Stenosis. ( 27127004 )
2016
9
OS 18-02 ANTIHYPERTENSIVE TREATMENT AND RISK OF BRAIN ISCHEMIA DUE TO CAROTID STENOSIS IN A SURVEY OF HOSPITALISED PATIENTS AGED 90 YEARS AND OLDER. ( 27642991 )
2016
10
Usefulness of Early Stenting for Symptomatic Extracranial Carotid Stenosis. ( 27641265 )
2016
11
Relationship Between Carotid Stenosis and Infarct Volume in Ischemic Stroke Patients. ( 27984560 )
2016
12
Is Carotid Revascularization Safe for Patients with Concomitant Carotid Stenosis and Intracranial Aneurysms? ( 27250773 )
2016
13
Stenting versus Surgery for Carotid Stenosis. ( 27517107 )
2016
14
Compensatory patterns of collateral flow in stroke patients with unilateral and bilateral carotid stenosis. ( 26987874 )
2016
15
Finding the optimal deconvolution algorithm for MR perfusion in carotid stenosis: Correlations with angiographic cerebral circulation time. ( 27038737 )
2016
16
Research of carotid stenosis in the elderly aged 80 and over in mountain towns. ( 27250225 )
2016
17
OS 18-02 ANTIHYPERTENSIVE TREATMENT AND RISK OF BRAIN ISCHEMIA DUE TO CAROTID STENOSIS IN A SURVEY OF HOSPITALISED PATIENTS AGED 90 YEARS AND OLDER. ( 27754070 )
2016
18
A prospective randomized trial comparing endarterectomy to stenting in severe asymptomatic carotid stenosis. ( 27332677 )
2016
19
Is anti-platelet therapy always necessary in asymptomatic 30-40% carotid stenosis? ( 27828829 )
2016
20
Double balloon protection during carotid artery stenting for vulnerable carotid stenosis reduces the incidence of new brain lesions. ( 27138330 )
2016
21
Commentary on 'Plaque Echolucency and the Risk of Ischaemic Stroke in Patients with Asymptomatic Carotid Stenosis Within the First Asymptomatic Carotid Surgery Trial (ACST-1)'. ( 26919935 )
2016
22
Stenting versus Surgery for Carotid Stenosis. ( 27509117 )
2016
23
The "seagull cry": An initial sign in a child with intracranial carotid stenosis. ( 27550894 )
2016
24
Intracranial collateral flow estimated by Color Velocity Imaging Quantification Ultrasound: a Protector of Recurrent Stroke in Patient with Carotid Stenosis? ( 27538891 )
2016
25
Endovascular Stenting versus Carotid Endarterectomy for Treatment of Severe Carotid Stenosis: Recent Results from ACT I and the Updated CREST Studies. ( 27262649 )
2016
26
Convexity subarachnoid haemorrhage secondary to internal carotid stenosis: an indication for revascularisation. ( 27118746 )
2016
27
Peritherapeutic Hemodynamic Changes of Carotid Stenting Evaluated with Quantitative DSA in Patients with Carotid Stenosis. ( 27173363 )
2016
28
Symptomatic carotid stenosis: is stenting as safe and effective as carotid endarterectomy? ( 28002136 )
2016
29
Tumor necrosis factor-I+ regulates triggering receptor expressed on myeloid cells-1-dependent matrix metalloproteinases in the carotid plaques of symptomatic patients with carotid stenosis. ( 27017522 )
2016
30
Amaurosis fugax: risk factors and prevalence of significant carotid stenosis. ( 27826182 )
2016
31
Stenting versus Surgery for Carotid Stenosis. ( 27509115 )
2016
32
Impact of acute cerebral ischemic lesions and their volume on the revascularization outcome of symptomatic carotid stenosis. ( 27751736 )
2016
33
Stenting versus Surgery for Carotid Stenosis. ( 27509114 )
2016
34
Stenting versus Surgery for Carotid Stenosis. ( 27509118 )
2016
35
Randomized Trial of Stent Versus Surgery for Asymptomatic Carotid Stenosis. ( 27763278 )
2016
36
Carotid calcification in panoramic radiographs: radiographic appearance and the degree of carotid stenosis. ( 27124572 )
2016
37
Autonomic outcome is better after endarterectomy than after stenting in patients with asymptomatic carotid stenosis. ( 27353359 )
2016
38
Dendritic Cells Expressing Triggering Receptor Expressed on Myeloid Cells-1 Correlate with Plaque Stability in Symptomatic and Asymptomatic Patients with Carotid Stenosis. ( 27148736 )
2016
39
Arterial Wall Imaging in Symptomatic Carotid Stenosis: Delayed Enhancement on MDCT Angiography. ( 26958408 )
2016
40
Stenting versus Surgery for Carotid Stenosis. ( 27509116 )
2016
41
Atherosclerotic carotid stenosis and cognitive function. ( 27152468 )
2016
42
Extracranial-intracranial bypass for internal carotid/middle cerebral atherosclerotic steno-occlusive diseases in conjunction with carotid endarterectomy for contralateral cervical carotid stenosis: clinical results and cognitive performance. ( 27026102 )
2016
43
Randomized Clinical Trial of Endovascular Stenting vs Endarterectomy for Treatment of Severe Carotid Stenosis. ( 27428641 )
2016
44
Homocysteine and Its Relationship to Asymptomatic Carotid Stenosis in a Chinese Community Population. ( 27869211 )
2016
45
Carotid Stenosis in Cardiac Surgery-No Difference in Postoperative Outcomes. ( 26906971 )
2016
46
Critical Issues That Need to Be Addressed to Improve Outcomes for Patients With Carotid Stenosis. ( 26922085 )
2016
47
The urgent need for contemporary clinical trials in patients with asymptomatic carotid stenosis. ( 27683853 )
2016
48
Re: 'Long-term Mortality in Patients with Asymptomatic Carotid Stenosis: Implications for Statin Therapy'. ( 27372439 )
2016
49
Radiotherapy of the neck and carotid stenosis. ( 27655500 )
2016
50
Using Flat-Panel Perfusion Imaging to Measure Cerebral Hemodynamics: A Pilot Feasibility Study in Patients With Carotid Stenosis. ( 27196456 )
2016

Variations for Carotid Stenosis

Expression for Carotid Stenosis

Search GEO for disease gene expression data for Carotid Stenosis.

Pathways for Carotid Stenosis

GO Terms for Carotid Stenosis

Sources for Carotid Stenosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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