MCID: CRR001
MIFTS: 32

Carrion's Disease malady

Infectious category

Summaries for Carrion's Disease

Sources:
8Disease Ontology, 3CDC, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Disease Ontology:8 A primary bacterial infectious disease that results in infection located in endothelial cells or located in red blood cells, has material basis in bartonella bacilliformis, which is transmitted by sandflies of genus lutzomyia. the infection has acute and chronic phases. the acute phase is characterized by severe hemolytic anemia and transient immunosuppression. the chronic phase is characterized by verruga peruana lesions which may ulcerate and bleed.

MalaCards: Carrion's Disease, also known as oroya fever, is related to granulomatous hepatitis and hepatitis b. An important gene associated with Carrion's Disease is MT-ND4 (mitochondrially encoded NADH dehydrogenase 4). The compounds 8-azido-atp and amp-pnp have been mentioned in the context of this disorder. Affiliated tissues include endothelial cells or, b cells and endothelial.

CDC:3 Bartonella bacteria cause several diseases in humans. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrión's disease, caused by B. bacilliformis.

Aliases & Classifications for Carrion's Disease

Sources:
8Disease Ontology, 49Orphanet, 61UMLS, 10DISEASES, 36MESH via Orphanet, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Aliases & Descriptions:

carrion's disease 8
oroya fever 8 49 61
bartonellosis due to bartonella bacilliformis infection 49
bartonella infections 61
carrions disease 10
carrion disease 49


External Ids:

Disease Ontology8 DOID:0050398
MESH via Orphanet36 D001474
ICD10 via Orphanet26 A44.0
SNOMED-CT via Orphanet58 186825001, 240453002, 262461007
UMLS via Orphanet62 C0029307, C0348974
ICD1025 A44, A44.9

Related Diseases for Carrion's Disease

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Carrion's Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1granulomatous hepatitis10.2
2hepatitis b10.2
3hepatitis c10.1
4cat-scratch disease10.1
5trench fever10.1
6juvenile rheumatoid arthritis10.1
7hepatitis d10.1
8granuloma annulare10.1
9arthritis10.1
10pyogenic granuloma10.1
11angiomatosis10.1
12blindness10.0MT-ND4
13colorectal cancer10.0HSPE1
14cystic fibrosis10.0HSPE1

Graphical network of diseases related to Carrion's Disease:



Diseases related to carrion's disease

Clinical Features for Carrion's Disease

Drugs & Therapeutics for Carrion's Disease

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Carrion's Disease

Drug clinical trials:

Search ClinicalTrials for Carrion's Disease

Search NIH Clinical Center for Carrion's Disease

Search CenterWatch for Carrion's Disease

Genetic Tests for Carrion's Disease

Anatomical Context for Carrion's Disease

Sources:
14FMA, 33MalaCards
See all sources

MalaCards organs/tissues related to Carrion's Disease:

33
B cells, Endothelial

FMA organs/tissues related to Carrion's Disease:

14
Endothelial cells or

Animal Models for Carrion's Disease or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Carrion's Disease

Sources:
51PubMed
See all sources

Articles related to Carrion's Disease:

idTitleAuthorsYear
1
Whole Genome Sequencing and Comparative Analysis of Bartonella bacilliformis Strain INS, the Causative Agent of Carrion's Disease. (23409255)
2013
2
A case of Carrion's disease associated with human sacrifice from the Huari culture of Southern Peru. (4606100)
1974
3
Pathogenesis of the verruga of Carrion's disease. Ultrastructural studies. (5060580)
1972
4
A study of 22 cases of Carrion's disease with intercurrent malaria. (15392068)
1949
5
ETIOLOGY OF OROYA FEVER : X. COMPARATIVE STUDIES OF DIFFERENT STRAINS OF BARTONELLA BACILLIFORMIS, WITH SPECIAL REFERENCE TO THE RELATIONSHIP BETWEEN THE CLINICAL TYPES OF CARRION'S DISEASE AND THE VIRULENCE OF THE INFECTING ORGANISM. (19869408)
1928

Genetic Variations for Carrion's Disease

Expression for genes affiliated with Carrion's Disease

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Carrion's Disease

Search GEO for disease gene expression data for Carrion's Disease.

Pathways for genes affiliated with Carrion's Disease

Compounds for genes affiliated with Carrion's Disease

Sources:
45Novoseek, 29IUPHAR, 24HMDB
See all sources

Compounds related to Carrion's Disease according to GeneCards/GeneDecks:

(show all 12)
idCompoundScoreTop Affiliating Genes
18-azido-atp459.6HSPE1, HSPD1
2amp-pnp45 2910.5HSPD1, HSPE1
3mgatp459.5HSPD1, HSPE1
4malate459.4HSPE1, HSPD1
5guanidine hydrochloride459.4HSPE1, HSPD1
6phorbol459.3HSPD1, ADORA2A
7citrate459.3HSPE1, HSPD1
8gold459.2HSPE1, HSPD1
9pyruvate459.1HSPE1, HSPD1, MT-ND4
10lactate459.0HSPE1, HSPD1, MT-ND4
11atp45 299.6ADORA2A, HSPE1, MT-ND4, HSPD1
12adp45 29 2410.5ADORA2A, HSPD1, HSPE1

GO Terms for genes affiliated with Carrion's Disease

Sources:
16Gene Ontology
See all sources

Biological processes related to Carrion's Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1activation of cysteine-type endopeptidase activity involved in apoptotic processGO:0069199.3HSPD1, HSPE1
2response to unfolded proteinGO:0069869.0HSPD1, HSPE1

Molecular functions related to Carrion's Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1unfolded protein bindingGO:0510829.3HSPD1, HSPE1
2chaperone bindingGO:0510879.0HSPD1, HSPE1

Products for genes affiliated with Carrion's Disease

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Carrion's Disease

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet