MCID: CTS002
MIFTS: 43

Cat-Scratch Disease malady

Categories: Rare diseases, Infectious diseases, Immune diseases

Aliases & Classifications for Cat-Scratch Disease

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Sources:
65UMLS, 10Disease Ontology, 12DISEASES, 51Orphanet, 36MeSH, 45NIH Rare Diseases, 35MedlinePlus, 2CDC, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 66UMLS via Orphanet, 28ICD10 via Orphanet, 37MESH via Orphanet
See all MalaCards sources

Aliases & Descriptions for Cat-Scratch Disease:

Name: Cat-Scratch Disease 10 12 51 36 65
Cat Scratch Disease 45 35 2
Bartonellosis Due to Bartonella Henselae Infection 45 51
Cat Scratch Fever 10 45
Debre's Syndrome 10 65
 
Foshay-Mollaret Cat Scratch Fever 10
Benign Lymphoreticulosis 10
Debre-Mollaret Syndrome 10
Oroya Fever 65

Characteristics:

Orphanet epidemiological data:

51
cat-scratch disease:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Adult

Classifications:



External Ids:

Disease Ontology10 DOID:11258
ICD1027 A28.1
ICD9CM29 078.3
MeSH36 D002372
NCIt42 C84620
Orphanet51 50839
UMLS via Orphanet66 C0007361
ICD10 via Orphanet28 A28.1
MESH via Orphanet37 D002372
UMLS65 C0007361, C0029307, C0543786

Summaries for Cat-Scratch Disease

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MedlinePlus:35 Cat scratch disease (csd) is an illness caused by the bacterium bartonella henselae. almost half of all cats carry the infection at some point. the infection does not make cats sick. however, the scratch or bite of an infected cat can cause symptoms in people, including swollen lymph nodes, especially around the head, neck, and upper limbs fever headache fatigue poor appetite for people with weak immune systems, csd may cause more serious problems. the best way to avoid csd is to avoid rough play with cats that could lead to scratches or bites. if you do get a scratch or bite, wash it well with soap and water. if the bite or scratch gets infected or if you have symptoms of csd, call your doctor. centers for disease control and prevention

MalaCards based summary: Cat-Scratch Disease, also known as cat scratch disease, is related to leukemia and prostatitis, and has symptoms including regional lymphadenopathy, headache and chills. An important gene associated with Cat-Scratch Disease is HTRA1 (HtrA Serine Peptidase 1), and among its related pathways are Mitochondrial protein import and Tuberculosis. Affiliated tissues include lymph node, lymph node and skin.

Disease Ontology:10 A bartonellosis that results in infection located in lymph node, has material basis in Bartonella henselae or has material basis in Bartonella clarridgeiae, which are transmitted by scratch or bite of a kitten, or transmitted by contact of animal's saliva with an eye or through broken skin. The infection has symptom regional lymphadenopathy, has symptom headache, has symptom chills, has symptom backache, and has symptom abdominal pain.

NIH Rare Diseases:45 Cat scratch disease is an infectious illness caused by the bacteria bartonella. it is believed to be transmitted by cat scratches, bites, or exposure to cat saliva. this self-limiting infectious disease is characterized by a bump or blister at the site of the bite or scratch and swelling and pain in the lymph nodes. other features may include fatigue, headache, achiness, and fever. although cat-scratch disease usually subsides without treatment, antibiotic and/or antimicrobial therapy may help speed recovery. last updated: 11/16/2015

CDC:2 Bartonella bacteria cause several diseases in humans. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrión's disease, caused by B. bacilliformis.

Wikipedia:68 Cat-scratch disease (CSD), also known as cat-scratch fever,Teeny\'s disease,inoculation... more...

Related Diseases for Cat-Scratch Disease

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Graphical network of the top 20 diseases related to Cat-Scratch Disease:



Diseases related to cat-scratch disease

Symptoms for Cat-Scratch Disease

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Symptoms:

 10
  • regional lymphadenopathy
  • headache
  • chills
  • backache
  • abdominal pain

Drugs & Therapeutics for Cat-Scratch Disease

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Drugs for Cat-Scratch Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AzithromycinapprovedPhase 432283905-01-555185, 53477736, 447043
Synonyms:
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*
121470-24-4
75199_FLUKA
83905-01-5
9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A
AC-16014
AC1L9KEG
Aritromicina
Azasite
Azenil
Azifast
Azigram
Azimakrol
Azithramycine
Azithromycin
Azithromycin & Tumor Necrosis Factor
Azithromycin (AIDS Initiative)
Azithromycin (anhydrous)
Azithromycin Dihydrate
Azithromycin Monohydrate
Azithromycin Sterile
Azithromycin dihydrate
Azithromycin plus Tumor Necrosis Factor
Azithromycine
Azithromycine [French]
Azithromycinum
Azithromycinum [Latin]
Azitrocin
Azitromax
Azitromicina
Azitromicina [Spanish]
Azitromin
Azythromycin
BIDD:GT0792
BRN 5387583
BSPBio_002285
Bio-0676
C38H72N2O12
CCRIS 1961
CHEBI:2955
CHEMBL529
CID447043
CP-62993
CP62,993
CPD000471864
DCH3
DRG-0104
 
DivK1c_000233
HMS1922G12
HMS2094M11
HMS500L15
HSDB 7205
Hemomycin
IDI1_000233
KBio1_000233
KBio2_000787
KBio2_003355
KBio2_005923
KBio3_001505
KBioGR_000731
KBioSS_000787
LS-1834
MLS001055353
MLS001066331
MLS001201763
MLS001304005
MLS001332499
MLS001332500
Misultina
MolPort-002-507-426
N,N-Dimethyl-4-amino-benzaldehyde
NCGC00090753-01
NCGC00090753-02
NINDS_000233
NSC643732
SAM002589961
SMR000471864
SPBio_001544
SPECTRUM1503679
Spectrum2_001582
Spectrum3_000653
Spectrum4_000186
Spectrum5_001867
Spectrum_000307
Sumamed
Tromix
UNII-JTE4MNN1MD
XZ-450
Z-Pak
ZIT
Zentavion
Zithromac
Zithromax
Zithromax IV
Zithromycin
Zitromax
Zitromax Avium 600
Zmas
Zmax
azithromycin
2
PrednisoneapprovedPhase 4126753-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
Juvason
 
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Perrigo Prednisone
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rayos
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
3ColaNutraceutical1768

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch DiseaseNot yet recruitingNCT01469702Phase 4
2Risk Factors of Cat Scratch Colon Developing.CompletedNCT01574547

Search NIH Clinical Center for Cat-Scratch Disease


Cochrane evidence based reviews: cat-scratch disease

Genetic Tests for Cat-Scratch Disease

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Anatomical Context for Cat-Scratch Disease

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MalaCards organs/tissues related to Cat-Scratch Disease:

33
Lymph node, Skin, Eye, T cells, Lung, Colon, Breast

FMA organs/tissues related to Cat-Scratch Disease:

16
Lymph node

Animal Models for Cat-Scratch Disease or affiliated genes

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Publications for Cat-Scratch Disease

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Articles related to Cat-Scratch Disease:

(show top 50)    (show all 537)
idTitleAuthorsYear
1
The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions. (25663698)
2015
2
Asymmetric Papilledema in Idiopathic Intracranial Hypertension: Comment. (26196848)
2015
3
Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid I^-amyloid 42: a cross-validation study against amyloid positron emission tomography. (25155658)
2014
4
Anemia and thrombocytopenia in Plasmodium vivax malaria is not unusual in patients from endemic and non-endemic settings. (25131143)
2014
5
Novel COL9A3 mutation in a family diagnosed with multiple epiphyseal dysplasia: a case report. (25381065)
2014
6
Increased accumulation of CD16+ monocytes at local sites of inflammation in patients with chronic kidney disease. (24111715)
2013
7
Peptides presented by HLA class I molecules in the human thymus. (24029068)
2013
8
Atrial Electromechanical Conduction Delay in Patients with Neurocardiogenic Syncope. (24215448)
2013
9
Juvenile fibromyalgia: current status of research and future developments. (24275966)
2013
10
The Self-Report Fecal Incontinence and Constipation Questionnaire in Patients With Pelvic-Floor Dysfunction Seeking Outpatient Rehabilitation. (24114438)
2013
11
Neuropsychological Outcomes After Psychosocial Intervention for Depression in Parkinson's Disease. (24275895)
2013
12
Fragmented QRS Complex in Adult Patients With Ebstein Anomaly and Its Association With Arrhythmic Risk and the Severity of the Anomaly. (24235269)
2013
13
Treatment of nodular basal cell carcinoma with cryotherapy and reduced protocol of imiquimod. (23270198)
2012
14
Mpg2 interacts and cooperates with Mpg1 to maintain yeast glycosylation. (22416758)
2012
15
Novel germline SDHD deletion associated with an unusual sympathetic head and neck paraganglioma. (20310044)
2011
16
DNA base excision repair gene polymorphisms modulate human cognitive performance and decline during normal life span. (21884718)
2011
17
Identification of muscle necrosis in the mdx mouse model of Duchenne muscular dystrophy using three-dimensional optical coherence tomography. (21806274)
2011
18
Laparoscopic sleeve gastrectomy for linear scleroderma. (20465430)
2010
19
Meta-analysis of incidence and risk of hypokalemia with cetuximab-based therapy for advanced cancer. (19760217)
2010
20
The mitogen-activated protein kinase signaling pathways: role in megakaryocyte differentiation. (19874462)
2010
21
Moyamoya disease: a clinical spectrum, literature review and case series from a tertiary care hospital in Pakistan. (19368734)
2009
22
Disseminated coccidioidomycosis: a case report from the United kingdom. (19294009)
2009
23
Characterization of childhood precursor T-lymphoblastic lymphoma by immunophenotyping and fluorescent in situ hybridization: a report from the Children's Oncology Group. (18618503)
2008
24
Neglected tropical cardiomyopathies: II. Endomyocardial fibrosis: myocardial disease. (18276824)
2008
25
Hypoalbuminemia in critically ill children. (17984406)
2007
26
Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration. (17994014)
2007
27
High prevalence of metallo-beta-lactamase-mediated resistance challenging antimicrobial therapy against Pseudomonas aeruginosa in a Brazilian teaching hospital. (16824253)
2007
28
Is blistering distal dactylitis a variant of bullous impetigo? (17362240)
2007
29
Congenital muscular dystrophy with muscle inflammation alpha dystroglycan glycosylation defect and no mutation in FKRP gene. (16386759)
2006
30
Methotrexate infusions as central nervous system prophylaxis in children with acute lymphocytic leukemia: the Norwegian experience. (12637215)
2003
31
Inhibition of Werner syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both strand-and stereoisomer-dependent. (12881525)
2003
32
Absence of pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein alpha-subunit gene in LbetaT2 gonadotrophs reveals disrupted cAMP-mediated gene transcription. (14519095)
2003
33
A case of myositis ossificans as a complication of tetanus treated by surgical excision. (12879713)
2003
34
Clinically significant persistence and enlargement of an antenatally diagnosed isolated choroid plexus cyst. (12493054)
2002
35
Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients. (11750132)
2001
36
Sildenafil (Viagra) and endolymphatic hydrops. (10993474)
2000
37
Effects of human cytochrome b5 on CYP3A4 activity and stability in vivo. (10334871)
1999
38
RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. (10613902)
1999
39
Action of human group IIa secreted phospholipase A2 on cell membranes. Vesicle but not heparinoid binding determines rate of fatty acid release by exogenously added enzyme. (9822691)
1998
40
Mixed connective tissue disease: a disease entity? (10374418)
1998
41
Anti-A2/RA33 autoantibodies are directed to the RNA binding region of the A2 protein of the heterogeneous nuclear ribonucleoprotein complex. Differential epitope recognition in rheumatoid arthritis, systemic lupus erythematosus, and mixed connective tissue disease. (9202064)
1997
42
Lymphoblastic transformation of chronic myelomonocytic leukemia in an infant. (8756090)
1996
43
Deletion of mitochondrial DNA in a case of early-onset diabetes mellitus, optic atrophy and deafness (DIDMOAD, Wolfram syndrome). (7609443)
1993
44
Effects of glutamate on exercise tolerance and circulating substrate levels in stable angina pectoris. (1967510)
1990
45
Secondary structure of the human T-cell leukemia virus type 1 rex-responsive element is essential for rex regulation of RNA processing and transport of unspliced RNAs. (2335818)
1990
46
Malignant nephroblastoma in Macaca fascicularis. (6292577)
1982
47
The remote effects of cancer on the nervous system: cerebellar degeneration. (889453)
1977
48
2-day treatment of trichomoniasis with nimorazole. (4425934)
1974
49
Congenital macroglossia. (5548986)
1971
50
Production of complementfixation test antigen for serodiagnosis of theileriasis in white-tailed deer (Odocoileus virginianus). (4986107)
1970

Variations for Cat-Scratch Disease

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Expression for genes affiliated with Cat-Scratch Disease

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Search GEO for disease gene expression data for Cat-Scratch Disease.

Pathways for genes affiliated with Cat-Scratch Disease

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Pathways related to Cat-Scratch Disease according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3CS, HSPD1
29.0CORO1A, EEA1, HSPD1

GO Terms for genes affiliated with Cat-Scratch Disease

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Cellular components related to Cat-Scratch Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1early endosomeGO:00057699.0CORO1A, EEA1, HSPD1

Biological processes related to Cat-Scratch Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of T cell activationGO:00508709.4CORO1A, HSPD1

Sources for Cat-Scratch Disease

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet