MCID: CTS002
MIFTS: 49

Cat-Scratch Disease malady

Rare diseases, Infectious diseases, Immune diseases categories

Summaries for Cat-Scratch Disease

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Sources:
9Disease Ontology, 44NIH Rare Diseases, 35MedlinePlus, 4CDC, 66Wikipedia, 34MalaCards
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MedlinePlus:35 Cat scratch disease (csd) is an illness caused by the bacterium bartonella henselae. almost half of all cats carry the infection at some point. the infection does not make cats sick. however, the scratch or bite of an infected cat can cause symptoms in people, including swollen lymph nodes, especially around the head, neck, and upper limbs fever headache fatigue poor appetite for people with weak immune systems, csd may cause more serious problems. the best way to avoid csd is to avoid rough play with cats that could lead to scratches or bites. if you do get a scratch or bite, wash it well with soap and water. if the bite or scratch gets infected or if you have symptoms of csd, call your doctor. centers for disease control and prevention

MalaCards: Cat-Scratch Disease, also known as bartonellosis due to bartonella henselae infection, is related to neuroretinitis and osteomyelitis, and has symptoms including abdominal pain, backache and chills. An important gene associated with Cat-Scratch Disease is HTRA1 (HtrA serine peptidase 1). Affiliated tissues include lymph node, lymph node and skin.

Disease Ontology:9 A primary bacterial infectious disease that results in infection located in lymph node, has material basis in bartonella henselae or has material basis in bartonella clarridgeiae, which are transmitted by scratch or bite of a kitten, or transmitted by contact of animal's saliva with an eye or through broken skin. the infection has symptom regional lymphadenopathy, has symptom headache, has symptom chills, has symptom backache, and has symptom abdominal pain.

NIH Rare Diseases:44 Cat scratch disease is an infectious illness caused by the bacteria bartonella. it is believed to be transmitted by cat scratches, bites, or exposure to cat saliva. this self-limiting infectious disease is characterized by swelling and pain in the lymph nodes. although cat-scratch disease usually subsides without treatment, antibiotic and/or antimicrobial therapy may speed recovery. last updated: 3/4/2009

CDC:4 Bartonella bacteria cause several diseases in humans. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrión's disease, caused by B. bacilliformis.

Wikipedia:66 Cat scratch disease (CSD), also known as cat scratch fever,Teeny\'s Disease,inoculation... more...

Aliases & Classifications for Cat-Scratch Disease

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Sources:
9Disease Ontology, 11DISEASES, 50Orphanet, 63UMLS, 44NIH Rare Diseases, 35MedlinePlus, 59SNOMED-CT, 28ICD9CM, 36MeSH, 41NCIt, 64UMLS via Orphanet, 37MESH via Orphanet, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases
Anatomical: Immune diseases


Characteristics (Orphanet epidemiological data):

50
cat-scratch disease:
Inheritance: Sporadic; Prevalence: 1-9/100000; Age of onset: Adulthood


Aliases & Descriptions:

cat-scratch disease 9 11 50 63
bartonellosis due to bartonella henselae infection 44 50
cat scratch disease 44 35
cat scratch fever 9 44
debre's syndrome 9 63
foshay-mollaret cat scratch fever 9
benign lymphoreticulosis 9
debre-mollaret syndrome 9


External Ids:

Disease Ontology9 DOID:11258
ICD9CM28 078.3
MeSH36 D002372
NCIt41 C84620
UMLS via Orphanet64 C0007361
MESH via Orphanet37 D002372
ICD10 via Orphanet27 A28.1
SNOMED-CT via Orphanet60 79974007
ICD1026 A28.1

Related Diseases for Cat-Scratch Disease

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Cat-Scratch Disease:



Diseases related to cat-scratch disease

Symptoms for Cat-Scratch Disease

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Sources:
9Disease Ontology
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Symptoms:

9
  • abdominal pain
  • backache
  • chills
  • headache
  • regional lymphadenopathy

Drugs & Therapeutics for Cat-Scratch Disease

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Cat-Scratch Disease

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Anatomical Context for Cat-Scratch Disease

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Sources:
34MalaCards, 15FMA
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MalaCards organs/tissues related to Cat-Scratch Disease:

34
Lymph node, Skin, Eye, Bone, Testes, Breast, Bone marrow, Liver, Spleen, Monocytes, T cells, Kidney, Colon, Endothelial

FMA organs/tissues related to Cat-Scratch Disease:

15
Lymph node

Animal Models for Cat-Scratch Disease or affiliated genes

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Publications for Cat-Scratch Disease

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Sources:
53PubMed
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Articles related to Cat-Scratch Disease:

(show top 50)    (show all 501)
idTitleAuthorsYear
1
Thoracic vertebral osteomyelitis with paraspinous mass and intraspinal extension: an atypical presentation of cat-scratch disease. (21594549)
2012
2
Bartonella henselae in skin biopsy specimens of patients with cat-scratch disease. (21122232)
2010
3
Images in emergency medicine. Right axillary mass. Cat scratch disease. (21111249)
2010
4
Cat scratch disease: clinical considerations for the pediatric dentist. (19320261)
2009
5
Mesenteric and splenic cat-scratch disease during etanercept therapy. (19690129)
2009
6
Localised retinal vasculitis in cat scratch disease. (21686569)
2009
7
Cat scratch disease. (19247139)
2009
8
Neuroretinitis secondary to concurrent infection with cat scratch disease and lyme disease. (18791545)
2009
9
Cat scratch disease with encephalopathy in a 9-year-old girl. (19067901)
2008
10
Severe occlusive vasculitis as a complication of cat scratch disease. (18454406)
2008
11
Beyond cat scratch disease: widening spectrum of Bartonella henselae infection. (18443019)
2008
12
Cat scratch disease. (17582885)
2007
13
Epidemiology of cat-scratch disease hospitalizations among children in the United States. (16094224)
2005
14
Papillary vasoproliferative changes in cat scratch disease. (15615761)
2005
15
Disseminated cat scratch disease with vertebral osteomyelitis and epidural abscess. (16351038)
2005
16
Cat scratch disease: an unusual cause of facial palsy and partial ptosis: case report. (15944991)
2005
17
Cat-scratch disease presenting as a breast mass. (15307578)
2004
18
Development of IgA nephritis following cat scratch disease in a 13-year-old boy. (15015065)
2004
19
Neck abscess secondary to cat-scratch disease. (15628637)
2004
20
Detection of Bartonella henselae DNA using polymerase chain reaction assay in patient with cat scratch disease. (12636034)
2003
21
Cat-scratch disease occurring in three siblings simultaneously. (12797315)
2003
22
Constrictive pericarditis following cat-scratch disease in a 12-year-old female: a rare association. (14635359)
2003
23
Magnetic resonance imaging abnormalities in cat-scratch disease encephalopathy. (12616083)
2003
24
Isolated splenic cat scratch disease. (12955654)
2003
25
Submacular exudates with serous retinal detachment caused by cat scratch disease. (12778351)
2002
26
From the Centers for Disease Control and Prevention. Cat-Scratch Disease in children--Texas, September 2000-August 2001. (12035788)
2002
27
Serodiagnosis of cat scratch disease: response to Bartonella henselae in children and a review of diagnostic methods. (11476439)
2001
28
Enzyme immunoassay for the diagnosis of cat-scratch disease defined by polymerase chain reaction. (11692296)
2001
29
Cat-scratch disease neuroretinitis diagnosed by a polymerase chain reaction approach. (11589885)
2001
30
Cervical lymphadenitis and cat scratch disease (CSD): an overlooked disease? (11205454)
2000
31
Prevalence of antibodies to Bartonella henselae in patients with suspected cat scratch disease (CSD) in Italy. (10485354)
1999
32
Images in clinical medicine. Cat scratch disease. (9887162)
1999
33
Radiological case of the month. Atypical cat-scratch disease. (10401812)
1999
34
Cat-scratch disease encephalopathy: a cause of status epilepticus in school-aged children. (10228301)
1999
35
Hypercalcemia due to endogenous overproduction of active vitamin D in identical twins with cat-scratch disease. (9480364)
1998
36
Cat-scratch disease in a patient undergoing haemodialysis. (9141021)
1997
37
The expanding spectrum of Bartonella infections: II. Cat-scratch disease. (9041596)
1997
38
Prevalence of Bartonella henselae bacteremia, the causative agent of cat scratch disease, in an Australian cat population. (8912359)
1996
39
Cat-scratch disease in Italy: a serological approach. (7526131)
1994
40
Cat scratch disease. (22050145)
1994
41
Disseminated hepatic and splenic calcifications following cat-scratch disease. (7824370)
1994
42
Cat scratch disease: past and present. (7532423)
1994
43
Cat-scratch disease presenting as a paravertebral abscess. A case report. (7989392)
1994
44
Generalized tonic-clonic status epilepticus in a child with cat-scratch disease and encephalopathy. (1582050)
1992
45
Oculoglandular syndrome. Cat-scratch disease without the cat scratch. (1561160)
1992
46
Cat-scratch disease. (1472219)
1992
47
Cat-scratch disease: therapy with trimethoprim-sulfamethoxazole. (1558070)
1992
48
Successful treatment of cat-scratch disease with ciprofloxacin. (1999905)
1991
49
Cat-scratch disease: an unusual cause of combative behavior. (1985652)
1991
50
Cerebral arteritis in cat-scratch disease. (573385)
1979

Variations for Cat-Scratch Disease

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Expression for genes affiliated with Cat-Scratch Disease

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cat-Scratch Disease

Search GEO for disease gene expression data for Cat-Scratch Disease.

Pathways for genes affiliated with Cat-Scratch Disease

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Compounds for genes affiliated with Cat-Scratch Disease

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GO Terms for genes affiliated with Cat-Scratch Disease

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Sources:
17Gene Ontology
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Biological processes related to Cat-Scratch Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1RNA metabolic processGO:0160709.3EXOSC5, RPL4
2mRNA metabolic processGO:0160719.0EXOSC5, RPL4

Products for genes affiliated with Cat-Scratch Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cat-Scratch Disease

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet