MCID: CTS002
MIFTS: 51

Cat-Scratch Disease malady

Infectious diseases, Immune diseases categories

Summaries for Cat-Scratch Disease

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 33MedlinePlus, 3CDC, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Cat scratch disease (csd) is an illness caused by the bacterium bartonella henselae. almost half of all cats carry the infection at some point. the infection does not make cats sick. however, the scratch or bite of an infected cat can cause symptoms in people, including swollen lymph nodes, especially around the head, neck, and upper limbs fever headache fatigue poor appetite for people with weak immune systems, csd may cause more serious problems. the best way to avoid csd is to avoid rough play with cats that could lead to scratches or bites. if you do get a scratch or bite, wash it well with soap and water. if the bite or scratch gets infected or if you have symptoms of csd, call your doctor. centers for disease control and prevention

MalaCards: Cat-Scratch Disease, also known as bartonellosis due to bartonella henselae infection, is related to endocarditis and tuberculosis, and has symptoms including abdominal pain, backache and chills. An important gene associated with Cat-Scratch Disease is HTRA1 (HtrA serine peptidase 1), and among its related pathways are Pyruvate metabolism and Citric acid cycle (TCA cycle). Affiliated tissues include lymph node, lymph node and skin.

Disease Ontology:8 A primary bacterial infectious disease that results in infection located in lymph node, has material basis in bartonella henselae or has material basis in bartonella clarridgeiae, which are transmitted by scratch or bite of a kitten, or transmitted by contact of animal's saliva with an eye or through broken skin. the infection has symptom regional lymphadenopathy, has symptom headache, has symptom chills, has symptom backache, and has symptom abdominal pain.

NIH Rare Diseases:42 Cat scratch disease is an infectious illness caused by the bacteria bartonella. it is believed to be transmitted by cat scratches, bites, or exposure to cat saliva. this self-limiting infectious disease is characterized by swelling and pain in the lymph nodes. although cat-scratch disease usually subsides without treatment, antibiotic and/or antimicrobial therapy may speed recovery. last updated: 3/4/2009

CDC:3 Bartonella bacteria cause several diseases in humans. The three most common are cat scratch disease, caused by B. henselae; trench fever, caused by B. quintana; and Carrión's disease, caused by B. bacilliformis.

Wikipedia:63 Cat scratch disease (CSD), also known as cat scratch fever,Teeny\'s Disease,inoculation... more...

Aliases & Classifications for Cat-Scratch Disease

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8Disease Ontology, 10DISEASES, 48Orphanet, 60UMLS, 42NIH Rare Diseases, 33MedlinePlus, 34MeSH, 39NCIt, 56SNOMED-CT, 27ICD9CM, 61UMLS via Orphanet, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Immune diseases


Characteristics (Orphanet epidemiological data):

48
cat-scratch disease:
Inheritance: Sporadic; Prevalence: 1-9/100000; Age of onset: Adulthood


Aliases & Descriptions:

cat-scratch disease 8 10 48 60
bartonellosis due to bartonella henselae infection 42 48
cat scratch disease 42 33
cat scratch fever 8 42
debre's syndrome 8 60
foshay-mollaret cat scratch fever 8
benign lymphoreticulosis 8
debre-mollaret syndrome 8


External Ids:

Disease Ontology8 DOID:11258
MeSH34 D002372
NCIt39 C84620
ICD9CM27 078.3
UMLS via Orphanet61 C0007361
MESH via Orphanet35 D002372
ICD10 via Orphanet26 A28.1
SNOMED-CT via Orphanet57 79974007
ICD1025 A28.1

Related Diseases for Cat-Scratch Disease

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Cat-Scratch Disease:



Diseases related to cat-scratch disease

Clinical Features for Cat-Scratch Disease

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Sources:
8Disease Ontology
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Symptoms:

8
  • abdominal pain
  • backache
  • chills
  • headache
  • regional lymphadenopathy

Drugs & Therapeutics for Cat-Scratch Disease

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Cat-Scratch Disease

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Anatomical Context for Cat-Scratch Disease

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Cat-Scratch Disease:

32
Lymph node, Skin, Eye, Bone, Testes, Breast, Bone marrow, Liver, Spleen, Monocytes, T cells, Kidney, Colon, Endothelial

FMA organs/tissues related to Cat-Scratch Disease:

14
Lymph node

Animal Models for Cat-Scratch Disease or affiliated genes

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Publications for Cat-Scratch Disease

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Sources:
50PubMed
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Articles related to Cat-Scratch Disease:

(show top 50)    (show all 502)
idTitleAuthorsYear
1
Cat-scratch disease in Northern Italy: atypical clinical manifestations in humans and prevalence of Bartonella infection in cats. (23132688)
2013
2
Thoracic vertebral osteomyelitis with paraspinous mass and intraspinal extension: an atypical presentation of cat-scratch disease. (21594549)
2012
3
Hip monoarthritis in a child with cat-scratch disease: Rare manifestation. (20958885)
2010
4
Cat scratch disease presenting with a retroperitoneal abscess in a patient without animal contacts. (20012734)
2009
5
Lymphadenopathy in a novel mouse model of Bartonella-induced cat scratch disease results from lymphocyte immigration and proliferation and is regulated by interferon-alpha/beta. (18292236)
2008
6
Evaluation of an internally controlled real-time polymerase chain reaction assay targeting the groEL gene for the detection of Bartonella spp. DNA in patients with suspected cat-scratch disease. (17624560)
2007
7
Effect of high-dose methyl-prednisolone on brainstem encephalopathy and basal ganglia impairment complicating cat scratch disease. (17174500)
2007
8
From cat scratch disease to endocarditis, the possible natural history of Bartonella henselae infection. (17442105)
2007
9
Musculoskeletal manifestations of cat scratch disease. (18190312)
2007
10
An unusual cutaneous presentation of cat-scratch disease. (17176268)
2007
11
Cat-scratch disease relapse in a kidney transplant recipient. (17239132)
2007
12
Images in clinical medicine. Cat scratch disease lymphadenopathy. (16641391)
2006
13
Multifocal osteomyelitis in a child: a rare manifestation of cat scratch disease: a case report and systematic review of the literature. (16751739)
2006
14
Pattern visual evoked potentials in eyes with disc swelling due to cat scratch disease-associated neuroretinitis. (16328936)
2005
15
Cat scratch disease in two brothers. (15179075)
2004
16
Cat scratch disease presenting as meningomyeloradiculopathy. (15210515)
2004
17
Cat-scratch disease presenting as a solitary tumour in the breast: report of three cases. (12551788)
2003
18
Neuroretinitis associated with cat-scratch disease in Japanese patients. (14641271)
2003
19
Submacular exudates with serous retinal detachment caused by cat scratch disease. (12778351)
2002
20
Epilepsia partialis continua as an atypical presentation of cat scratch disease in a young adult. (12473786)
2002
21
Cat-scratch disease in children--Texas, September 2000-August 2001. (11922191)
2002
22
Enzyme immunoassay for the diagnosis of cat-scratch disease defined by polymerase chain reaction. (11692296)
2001
23
Bartonella henselae bacteraemia in patients with cat scratch disease. (11388603)
2001
24
Cat scratch disease (bartonellosis) mimicking an SLE flare. (11787880)
2001
25
Differential detection of Bartonella species and strains in cat scratch disease diagnostics by polymerase chain reaction amplification of 16S ribosomal RNA gene. (11482599)
2001
26
Cervical lymphadenitis and cat scratch disease (CSD): an overlooked disease? (11205454)
2000
27
Parapharyngeal abscess due to cat-scratch disease. (10722453)
2000
28
Recurrent encephalopathy in cat-scratch disease. (10391197)
1999
29
Anterior uveitis associated with cat scratch disease. (9713073)
1998
30
Azithromycin for the treatment of cat-scratch disease. (9455538)
1998
31
Cat-scratch disease manifesting as unifocal helioid choroiditis. (9747695)
1998
32
Chest-wall abscess due to cat-scratch disease (CSD) in an adult with antibodies to Bartonella clarridgeiae: case report and review of the thoracopulmonary manifestations of CSD. (9709886)
1998
33
Application of polymerase chain reaction assay in the diagnosis of orbital granuloma complicating atypical oculoglandular cat scratch disease. (9224472)
1997
34
Will the real agent of cat-scratch disease please stand up? (8905096)
1996
35
Cat-scratch disease. (8794184)
1996
36
Cat scratch disease and acquired immunodeficiency disease: diagnosis by transmission electron microscopy. (8727061)
1996
37
Acquisition of the cat scratch disease agent Bartonella henselae by cat fleas (Siphonaptera:Pulicidae). (8667399)
1996
38
Re: Imaging features of cat-scratch disease. (8911215)
1996
39
Cat-scratch disease associated with pleural effusions and encephalopathy in a child. (7569342)
1995
40
Uncomplicated cat-scratch disease: findings at CT, MR imaging, and radiography. (7754017)
1995
41
Cat scratch disease. (7527210)
1994
42
Systemic cat-scratch disease in a pediatric liver transplant recipient and review of the literature. (8018131)
1993
43
Cat scratch disease in the United States: an analysis of three national databases. (8259799)
1993
44
Hepatosplenic cat-scratch disease associated with elevated anti-Rochalimaea antibody titers. (8284124)
1993
45
Cat-scratch disease mimicking rhabdomyosarcoma. (8265222)
1993
46
Oculoglandular syndrome. Cat-scratch disease without the cat scratch. (1561160)
1992
47
Cat-scratch disease. (1472219)
1992
48
Cat-scratch disease: an unusual cause of combative behavior. (1985652)
1991
49
Monocytoid B lymphocytes and epithelioid cell clusters in abscess-forming granulomatous lymphadenitis. With special reference to cat scratch disease. (1714225)
1991
50
Epithelioid angiomatosis secondary to disseminated cat scratch disease involving the bone marrow and skin in a patient with acquired immune deficiency syndrome: a case report. (2301445)
1990

Genetic Variations for Cat-Scratch Disease

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Expression for genes affiliated with Cat-Scratch Disease

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cat-Scratch Disease

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Pathways for genes affiliated with Cat-Scratch Disease

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Sources:
53Reactome, 37NCBI BioSystems Database, 29KEGG
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Pathways related to Cat-Scratch Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.7DLST, CS
2
Hide members
9.7DLST, CS

Compounds for genes affiliated with Cat-Scratch Disease

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GO Terms for genes affiliated with Cat-Scratch Disease

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Sources:
16Gene Ontology
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Cellular components related to Cat-Scratch Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:0058298.1SDCBP, EEA1, AGL, HTRA1, EXOSC5, RPL4
2cytoplasmGO:0057376.3SDCBP, RPL4, EXOSC5, UBASH3B, PPP1R14A, AGL

Biological processes related to Cat-Scratch Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of JNK cascadeGO:0463309.5SDCBP, TNF
2tricarboxylic acid cycleGO:0060999.4DLST, CS

Products for genes affiliated with Cat-Scratch Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cat-Scratch Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet