MCID: CTR103
MIFTS: 34

Cataract 4, Multiple Types malady

Categories: Genetic diseases, Rare diseases, Neuronal diseases, Eye diseases, Fetal diseases

Aliases & Classifications for Cataract 4, Multiple Types

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Aliases & Descriptions for Cataract 4, Multiple Types:

Name: Cataract 4, Multiple Types 49 11 67 65
Cataract 4, Multiple Types, with or Without Microcornea 67
Punctate, Progressive Juvenile-Onset, Cataract 67
Congenital Non-Nuclear Polymorphic Cataract 67
Nonnuclear Polymorphic Congenital Cataract 65
Cataract, Congenital, Cerulean Type, 3 65
Congenital Cataract Cerulean Type 3 67
Congenital Cataract Blue Dot Type 3 67
 
Crystalline Aculeiform Cataract 67
Aculeiform Cataract 67
Pheochromocytoma 65
Ctrct4 67
Caca 67
Cca3 67
Pcc 67
Ccp 67

Characteristics:

HPO:

61
cataract 4, multiple types:
Inheritance: autosomal dominant inheritance


Classifications:



External Ids:

OMIM49 115700
MeSH36 D002386
UMLS65 C1837023, C0031511, C3888391 C3540850, more

Summaries for Cataract 4, Multiple Types

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UniProtKB/Swiss-Prot:67 Cataract 4, multiple types: An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. CTRCT4 includes crystalline aculeiform, congenital cerulean and non-nuclear polymorphic cataracts, among others. Crystalline aculeiform cataract is characterized by fiberglass-like or needle-like crystals projecting in different directions, through or close to the axial region of the lens. Non- nuclear polymorphic cataract is a partial opacity with variable location between the fetal nucleus of the lens and the equator. The fetal nucleus is normal. The opacities are irregular and look similar to a bunch of grapes and may be present simultaneously in different lens layers. Congenital cerulean cataract is characterized by peripheral bluish and white opacifications organized in concentric layers with occasional central lesions arranged radially. The opacities are observed in the superficial layers of the fetal nucleus as well as the adult nucleus of the lens. Involvement is usually bilateral. Visual acuity is only mildly reduced in childhood. In adulthood, the opacifications may progress, making lens extraction necessary. Histologically the lesions are described as fusiform cavities between lens fibers which contain a deeply staining granular material. Although the lesions may take on various colors, a dull blue is the most common appearance and is responsible for the designation cerulean cataract.

MalaCards based summary: Cataract 4, Multiple Types, also known as cataract 4, multiple types, with or without microcornea, is related to pheochromocytoma and propionicacidemia, and has symptoms including congenital cataract An important gene associated with Cataract 4, Multiple Types is CRYGD (Crystallin Gamma D), and among its related pathways are Pyruvate metabolism and Citric Acid (TCA) cycle and Citrate cycle (TCA cycle). The drugs propranolol and propranolol hydrochloride have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and endothelial.

OMIM:49 Mutations in the CRYGD gene have been found to cause multiple types of cataract, which have been described as... (115700) more...

Related Diseases for Cataract 4, Multiple Types

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Diseases in the Cataract family:

Cataract 8, Multiple Types Cataract 6, Multiple Types
Cataract 34, Multiple Types Cataract 1, Multiple Types
Cataract 39, Multiple Types, Autosomal Dominant Cataract 2, Multiple Types
cataract 4, multiple types Cataract 42
Cataract 18, Autosomal Recessive Cataract 20, Multiple Types
Cataract 41 Cataract 38, Autosomal Recessive
Cataract 26, Multiple Types Cataract 36
Cataract 11, Multiple Types Cataract 16, Multiple Types
Cataract 15, Multiple Types Cataract 14, Multiple Types
Cataract 32, Multiple Types Cataract 25
Cataract 5, Multiple Types Cataract 21, Multiple Types
Cataract 43 Cataract 10, Multiple Types
Cataract 7 Cataract 19
Cataract 33 Cataract 31, Multiple Types
Cataract 9, Multiple Types Cataract 44
Cataract 17, Multiple Types Cataract 3, Multiple Types
Cataract 22, Autosomal Recessive Cataract 23
Cataract Congenital Autosomal Dominant Cataract, Total Congenital
Cataract, Autosomal Dominant Congenital 4 Cataracts, Autosomal Recessive
Foxe3-Related Cataracts, Autosomal Dominant Total Early-Onset Cataract

Diseases related to Cataract 4, Multiple Types via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 91)
idRelated DiseaseScoreTop Affiliating Genes
1pheochromocytoma30.8KIF1B, RET, SDHB, SDHD, TMEM127
2propionicacidemia11.5
3cataract, autosomal dominant congenital 411.4
4cataract congenital dominant non nuclear11.4
5microcephaly 1, primary, autosomal recessive11.3
6leukemia10.4
7rheumatoid arthritis10.4
8obesity10.4
9arthritis10.4
10hyperphosphatemia10.2
11phaeochromocytoma10.2
12lymphoma10.2
13prostatitis10.2
14calciphylaxis10.2
15neuronitis10.2
16familial stomach cancer10.1SDHB, SDHD
17neuroaxonal dystrophy renal tubular acidosis10.1SDHB, SDHD
18paraganglioma and gastric stromal sarcoma10.1SDHB, SDHD
19lung cancer10.0
20prostate cancer10.0
21breast cancer10.0
22hepatitis c virus10.0
23cherubism10.0
24keratitis10.0
25waisman syndrome10.0
26follicular lymphoma10.0
27hepatitis10.0
28mycosis fungoides10.0
29neuromyelitis optica10.0
30amblyopia10.0
31tonsillitis10.0
32hypohidrosis10.0
33arteriovenous malformation10.0
34hypophosphatasia10.0
35cheilitis10.0
36hepatitis c10.0
37melanoma10.0
38cholecystitis10.0
39vulvar melanoma10.0
40gangliosidosis10.0
41neonatal jaundice10.0
42angiodysplasia10.0
43papilloma10.0
44pulmonary tuberculosis10.0
45leukemoid reaction10.0
46inverted papilloma10.0
47tuberculosis10.0
48seminoma10.0
49pituitary carcinoma10.0
50thyroiditis10.0

Graphical network of the top 20 diseases related to Cataract 4, Multiple Types:



Diseases related to cataract 4, multiple types

Symptoms for Cataract 4, Multiple Types

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Symptoms by clinical synopsis from OMIM:

115700

Clinical features from OMIM:

115700

HPO human phenotypes related to Cataract 4, Multiple Types:

id Description Frequency HPO Source Accession
1 congenital cataract HP:0000519

Drugs & Therapeutics for Cataract 4, Multiple Types

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Drugs for Cataract 4, Multiple Types (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 88)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MethylprednisoloneapprovedPhase 4108283-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
2
PrednisoneapprovedPhase 4126753-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
Juvason
 
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Perrigo Prednisone
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rayos
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
3
Daclizumabapproved, investigationalPhase 496152923-56-3
Synonyms:
Anti-IL-2
Humanized antiCD25
 
Ig gamma-1 chain C region
Simulect
chimeric mouse-human antiCD25
4
PrednisoloneapprovedPhase 4108250-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
5
Mycophenolic acidapprovedPhase 4, Phase 1, Phase 289824280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
Melbex
 
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolic Acid
Mycophenolsaeure
Myfortic
6
Mycophenolate mofetilapproved, investigationalPhase 4, Phase 1, Phase 2898128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate Mofetil
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
7
KetorolacapprovedPhase 427866635-83-43826
Synonyms:
(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(+-)-Ketorolac
(+-)-isomer
(.+/-.)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
66635-83-4
74103-06-3
AB00053682
AC-545
AC1L1GSW
Acular
Acuvail
BRD-A40639672-234-05-7
C07062
CHEBI:105080
CHEMBL469
CID3826
D020910
D08104
DB00465
 
I14-2832
Ketoralac
Ketorolac
Ketorolac (INN)
Ketorolac Tromethamine
Ketorolac [INN:BAN]
Ketorolaco
Ketorolaco [Spanish]
Ketorolacum
Ketorolacum [Latin]
Kétorolac
LS-139094
Macril
MolPort-005-933-093
NCGC00185990-01
RS 37619
RS-37619
SBB067312
STL018674
Sprix
Toradol (TN)
UNII-YZI5105V0L
ketorolac
rac-Ketorolac
8
Tacrolimusapproved, investigationalPhase 41023104987-11-3445643, 439492, 445647
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
8-DEETHYL-8-[but-3-enyl]-ascomycin
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
FR900506
 
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
Hecoria
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus Hydrate
Tacrolimus anhydrous
Tacrolimus hydrate
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
9
Isosorbide DinitrateapprovedPhase 45687-33-26883
Synonyms:
1,4:3, 6-Dianhydro-D-glucitol dinitrate
1,4:3,6-Dianhydro-D-glucitol dinitrate
1,4:3,6-Dianhydrosorbitol 2, 5-dinitrate
1,4:3,6-Dianhydrosorbitol 2,5-dinitrate
1,4:3,6-dianhydro-2,5-di-O-nitro-D-glucitol
54650-95-2
59812_ALDRICH
59812_FLUKA
6659-58-1
87-33-2
AB00513900
AC-12153
AC1L1NIG
Angidil
Astridine
BPBio1_001021
BSPBio_000927
BSPBio_002080
BiDil
C07456
C6H8N2O8
CCRIS 1910
CHEBI:6061
CID6883
Cardio 10
Cardis
Cardonit 40
Carvanil
Carvasin
Cedocard
Cedocard Retard
Cedocard retard
Claodical
Cornilat
Coronex
Corosorbide
Corovliss
D-Glucitol, 1,4:3,6-dianhydro-, 2,5-dinitrate
D-Glucitol, 1,4:3,6-dianhydro-, dinitrate
D-Isosorbide dinitrate
D-Isosorbide dinitrate-Lactose mixture
D00516
D007548
DB00883
Dianhydrosorbitol 2,5-dinitrate
Difutrat
Dignionitrat
Dilatrate
Dilatrate SR
Dilatrate-SR
Dilatrate-sr (TN)
Diniket
Dinitrate d'isosorbide
Dinitrate d'isosorbide [INN-French]
Dinitrate, Isosorbide
Dinitrato de isosorbida
Dinitrato de isosorbida [INN-Spanish]
Dinitroisosorbide
Dinitrosorbide
Disorlon
DivK1c_000436
EINECS 201-740-9
Emoper
EureCor
Flindix
Frandol
Glucitol, 1,4:3, 6-dianhydro-, dinitrate,
HMS1570O09
HMS1920H15
HMS2091P05
HMS501F18
HSDB 3417
Harrical
IBD 20
IDI1_000436
ISD
ISDN
ISOSORBIDE DINITRATE
Ismotic
Iso Bid
Iso-Bid
Iso-Mack
Iso-Puren
IsoBid
Isochron
Isodinit
Isoket
Isoket Retard 120
Isoket Retard-120
Isoket Retard120
Isoket retard 40
Isomak R
 
Isorbid
Isordil
Isordil (TN)
Isordil Tembids
Isordil Titradose
Isosorbide
Isosorbide 2,5-dinitrate
Isosorbide Dinitrate
Isosorbide Sublingual
Isosorbide dinitrate
Isosorbide dinitrate (JP15/USP/INN)
Isosorbide dinitrate [USAN:INN:BAN:JAN]
Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate [UN2907] [Flammable solid]
Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate [UN2907] [Flammable solid]
Isosorbide dinitrato
Isosorbide dinitrato [DCIT]
Isosorbidi dinitras
Isosorbidi dinitras [INN-Latin]
Isosorbidi nitras
Isostat
Isotrate
KBio1_000436
KBio2_000643
KBio2_003211
KBio2_005779
KBio3_001580
KBioGR_000429
KBioSS_000643
Korodil
LS-71376
Langoran
Laserdil
Lomilan
MLS001333561
MLS001333562
Maycor
MolPort-003-666-213
Myorexon
NCGC00178830-01
NCGC00178830-02
NINDS_000436
NSC 80038
NSC80038
Nitrosorbid
Nitrosorbide
Nitrosorbon
Nosim
Prestwick0_000714
Prestwick1_000714
Prestwick2_000714
Prestwick3_000714
Prestwick_81
Resoidan
Rifloc Retard
Rigedal
SDM No. 40
SDM No. 50
SMR000857256
SPBio_001058
SPBio_002848
SPECTRUM1500358
SST-101
Sorate-10
Sorate-5
Sorbangil
Sorbide
Sorbide T.D.
Sorbide nitrate
Sorbide, dinitrate
Sorbidi nitras
Sorbidilat
Sorbidinitrate
Sorbidnitrate
Sorbislo
Sorbitrate
Sorbonit
Sorquad
Sorquat
Spectrum2_001069
Spectrum3_000600
Spectrum4_000025
Spectrum5_001057
Spectrum_000163
TYB 3215
Tinidil
Titradose
UN2907
UNII-IA7306519N
Vascardin
Vasodilat
Vasorbate
Xanyl
ZINC18089317
[(3S,3aS,6R,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate
10
Nitric OxideapprovedPhase 456410102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
Inomax
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
11Methylprednisolone HemisuccinatePhase 41082
12Immunologic FactorsPhase 4, Phase 1, Phase 218483
13Methylprednisolone acetatePhase 41082
14Immunosuppressive AgentsPhase 4, Phase 1, Phase 210422
15Prednisolone acetatePhase 41082
16Protective AgentsPhase 45651
17Phase 4
18Prednisolone phosphatePhase 41082
19Prednisolone hemisuccinatePhase 41082
20ImmunoglobulinsPhase 4, Phase 1, Phase 24477
21Neuroprotective AgentsPhase 41376
22Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 39988
23Ketorolac TromethaminePhase 4278
24Peripheral Nervous System AgentsPhase 418510
25Anti-Bacterial AgentsPhase 4, Phase 1, Phase 29140
26Cyclooxygenase InhibitorsPhase 42225
27Antirheumatic AgentsPhase 4, Phase 1, Phase 28496
28Analgesics, Non-NarcoticPhase 45184
29Anti-Inflammatory AgentsPhase 4, Phase 38478
30Anti-Inflammatory Agents, Non-SteroidalPhase 43549
31AnalgesicsPhase 49358
32Antibiotics, AntitubercularPhase 4, Phase 1, Phase 25971
33glucocorticoidsPhase 4, Phase 33896
34Hormone AntagonistsPhase 4, Phase 310002
35HormonesPhase 4, Phase 3, Phase 1, Phase 211748
36AntibodiesPhase 4, Phase 1, Phase 24477
37Gastrointestinal AgentsPhase 46401
38Antibodies, MonoclonalPhase 42413
39Calcineurin InhibitorsPhase 4, Phase 1, Phase 21223
40Antineoplastic Agents, HormonalPhase 44256
41AntiemeticsPhase 43213
42Vasodilator AgentsPhase 42926
43Nitric Oxide DonorsPhase 4100
44Natriuretic AgentsPhase 41403
45isosorbide-5-mononitratePhase 456
46diureticsPhase 41194
47IsosorbidePhase 456
48
Beclomethasoneapproved, investigationalPhase 31594419-39-0, 5534-09-820469, 21700
Synonyms:
(11beta,16beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
(11beta,16beta)-9-chloro-11-Hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
(8R,9S,10S,11S,13R,14R,16R,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
4419-39-0
9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
9-chloro-11beta-Hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
9-chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
9-chloro-16beta-Methyl-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-dipropionate
9alpha-Chloro-11beta,17alpha,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
9alpha-Chloro-16beta-methyl-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione
9alpha-Chloro-16beta-methylprednisolone
9α-chloro-16β-methylprednisolone
AC1L1DDX
AC1L2GBM
AC1O7G0A
Aerobec
Aldecin
Anceron
Andion
B 0385
B0385_SIGMA
BCBcMAP01_000159
BIDD:GT0556
BMJ 5800
Beclacin
Beclocort
Becloforte
Beclomet
Beclometason
Beclometason (TN)
Beclometasona
Beclometasona [INN-Spanish]
Beclometasondipropionat Mikron
Beclometasone
Beclometasone (INN)
Beclometasone 17,21-dipropionate
Beclometasone [INN]
Beclometasone dipropionate
Beclometasonum
Beclometasonum [INN-Latin]
Beclomethasone dipropionate
Beclorhinol
Becloval
Beclovent
Becodisks
Beconase
Beconasol
Becotide
C06842
 
C22H29ClO5
CHEBI:3001
CHEMBL1586
CID11407187
CID11957468
CID20469
CID2308
CID6603734
CPD000466920
Clenil-a
D07495
DB00394
EINECS 224-585-9
EU-0100159
Entyderma
HMS2052E17
Inalone
Korbutone
LS-174992
Lopac-B-0385
Lopac0_000159
MLS000028668
MLS001076089
MLS001333211
MLS001333212
MLS001424231
MLS002153387
MolPort-003-844-701
MolPort-003-940-375
NCGC00015136-01
NCGC00015136-02
NCGC00093647-01
NCGC00162078-01
NCGC00162078-02
NCGC00164402-01
Propaderm
Qnasl
Qvar
Rino-clenil
SAM001246898
SMP1_000039
SMR000058899
SMR000466920
Sanasthmax
Sanasthmyl
UNII-KGZ1SLC28Z
Vancenase
Vancenase AQ
Vanceril
Viarex
Viarox
ZINC04097285
beclomethasone
49
Ciclesonideapproved, investigationalPhase 374141845-82-1444033
Synonyms:
(R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate
126544-47-6
141845-82-1
AC-1330
Alvesco
Alvesco (TN)
Alvesco HFA
B-9207-015
BTR-15
BTR-15K
BY-9010
BYK-20426
CID6918155
Ciclesonide
 
Ciclesonide (JAN/USAN/INN)
Ciclesonide [INN]
D01703
KS-1165
LS-186047
MolPort-005-940-705
NCGC00167972-01
Omnair
Omnaris
Omnaris HFA
Osonase
Osonide
RPR 251526
TBN-15
UNII-S59502J185
Zetonna
50
MelphalanapprovedPhase 3685148-82-34053, 460612
Synonyms:
(2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
(2s)-2-amino-3-(4-[bis(2-chloroethyl)amino]phenyl)propanoic acid
148-82-3
3-(P-(Bis(2-chloroethyl)amino)phenyl)-L-alanine
3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine
3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
3-P-(Di(2-chloroethyl)amino)-phenyl-L-alanine
3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine
3025 C.B.
3025 c.b
3223-07-2
4-(Bis(2-chloroethyl)amino)-L-phenylalanine
4-14-00-01689 (Beilstein Handbook Reference)
4-[Bis(2-chloroethyl)amino]-L-phenylalanine
4-[Bis-(2-chloroethyl)amino]-L-phenylalanine
AC1LA2OE
ALKERAN (TN)
AY3360000
Alanine Nitrogen Mustard
Alkeran
AmbotzHAA1563
At-290
BIDD:GT0044
BRD-K87827419-001-02-8
BRN 2816456
BSPBio_002407
C13H18Cl2N2O2
CB 3025
CB-3025
CCRIS 374
CHEBI:165415
CHEBI:28876
CHEMBL852
CID460612
D00369
DivK1c_000653
EINECS 205-726-3
HMS2090B09
HMS2091B16
HMS502A15
HSDB 3234
IDI1_000653
KBio1_000653
KBio2_000877
KBio2_003445
KBio2_006013
KBio3_001627
KBioGR_001284
KBioSS_000877
L-3-(P-(Bis(2-chloroethyl)amino)phenyl)alanine
L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
L-3-(para-(Bis(2-chloroethyl)amino)phenyl)alanine
L-PAM
L-Phenylalanine mustard
L-Sarcolysin
L-Sarcolysine
L-Sarkolysin
LS-15868
LS-865
Levofalan
 
Levofolan
Levopholan
M2011_SIGMA
MELPHALAN (SEE ALSO TRANSGENIC MODEL EVALUATION (MELPHALAN))
MLS001333666
MLS002153368
Melfalan
Melfalano
Melfalano [INN-Spanish]
Melphalan (JP15/USP/INN)
Melphalan Hydrochloride
Melphalan [USAN:INN:BAN:JAN]
Melphalan hydrochloride
Melphalanum
Melphalanum [INN-Latin]
Mephalan
MolPort-003-665-535
NCGC00090757-01
NCGC00090757-02
NCGC00090757-03
NCI-C04853
NINDS_000653
NIOSH/AY3360000
NSC 241286
NSC 8806
NSC-8806
NSC241286
NSC8806
P-Di-(2-chloroethyl)amino-L-phenylalanine
P-L-Sarcolysin
P-N-Bis(2-chloroethyl)amino-L-phenylalanine
Phenylalanine mustard
Phenylalanine nitrogen mustard
Prestwick_1006
RCRA waste no. U150
Rcra waste number U150
SK-15673
SMP2_000174
SMR000058720
SPBio_000287
SPECTRUM1500382
Sarcolysine
Sarkolysin
Spectrum2_000074
Spectrum3_000684
Spectrum4_000882
Spectrum5_001601
Spectrum_000397
TL8001065
TRANSGENIC LEP (MELPHALAN) (SEE ALSO MELPHALAN)
TRANSGENIC MODEL EVALUATION (MELPHALAN)
UNII-Q41OR9510P
melphalan
p-Bis(beta-chloroethyl)aminophenylalanine
p-Di-(2-chloroethyl)amino-L-phenylalanine
p-L-Sarcolysin
p-L-sarcolysine
p-N,N-bis(2-chloroethyl)amino-L-phenylalanine
p-N-Bis(2-chloroethyl)amino-L-phenylalanine
p-N-Di(chloroethyl)aminophenylalanine
p-N-di(chloroethyl)aminophenylala nine
phenylalanine nitrogen mu stard

Interventional clinical trials:

idNameStatusNCT IDPhase
1Protein Profile of Immunoregulatory Factors in Diabetic CataractCompletedNCT01832311Phase 4
2Phase IV Study to Evaluate Calcineurin Inhibitor Reduced, Steroid Free Immunosuppression After Renal TransplantationCompletedNCT00724022Phase 4
3Mechanical vs. Alcohol Separation of the Corneal Epithelium During Surface Ablation Refractive ProceduresCompletedNCT00366808Phase 4
4Influence of Nitrates on Bone Remodeling and Endothelial Function in Patients With Type 2 Diabetes MellitusNot yet recruitingNCT02011620Phase 4
5A Intra-patient Comparison of Closed Loop and Plate Haptic Toric Intraocular LensesNot yet recruitingNCT02264457Phase 4
6Clinical Investigation of the Bi Flex M Multifocal IOLNot yet recruitingNCT02338882Phase 4
7A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Multiple MyelomaCompletedNCT00434161Phase 3
8Effects Of Ciclesonide And Beclomethasone On Lens Opacification In Adult Subjects With Moderate To Severe Persistent AsthmaCompletedNCT00254956Phase 3
9Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic CancerActive, not recruitingNCT00245037Phase 1, Phase 2
10Long-term Topical Cyclosporine for Atopic KeratoconjunctivitisCompletedNCT00987467

Search NIH Clinical Center for Cataract 4, Multiple Types

Inferred drug relations via UMLS65/NDF-RT43:

Genetic Tests for Cataract 4, Multiple Types

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Anatomical Context for Cataract 4, Multiple Types

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MalaCards organs/tissues related to Cataract 4, Multiple Types:

33
Eye, Bone, Endothelial

Animal Models for Cataract 4, Multiple Types or affiliated genes

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MGI Mouse Phenotypes related to Cataract 4, Multiple Types:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Cataract 4, Multiple Types

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Variations for Cataract 4, Multiple Types

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UniProtKB/Swiss-Prot genetic disease variations for Cataract 4, Multiple Types:

67
id Symbol AA change Variation ID SNP ID
1CRYGDp.Arg15CysVAR_010733
2CRYGDp.Arg37SerVAR_010734
3CRYGDp.Arg59HisVAR_010735
4CRYGDp.Pro24ThrVAR_021145
5CRYGDp.Pro24SerVAR_034955rs28931605
6CRYGDp.Glu107AlaVAR_034956
7CRYGDp.Trp43ArgVAR_064829

Clinvar genetic disease variations for Cataract 4, Multiple Types:

5 (show all 25)
id Gene Variation Type Significance SNP ID Assembly Location
1TMEM127NM_017849.3(TMEM127): c.475C> T (p.Gln159Ter)single nucleotide variantLikely pathogenic, Pathogenic, risk factorrs121908830GRCh37Chr 2, 96919788: 96919788
2SDHBNM_003000.2(SDHB): c.268C> T (p.Arg90Ter)single nucleotide variantPathogenicrs74315366GRCh37Chr 1, 17359573: 17359573
3SDHBNM_003000.2(SDHB): c.725G> A (p.Arg242His)single nucleotide variantPathogenicrs74315368GRCh37Chr 1, 17349143: 17349143
4SDHBNM_003000.2(SDHB): c.716_719delCTCT (p.Ser239Tyrfs)deletionPathogenicrs587781266GRCh38Chr 1, 17022654: 17022657
5SDHBNM_003000.2(SDHB): c.79C> T (p.Arg27Ter)single nucleotide variantPathogenicrs74315369GRCh37Chr 1, 17371377: 17371377
6RETNM_020975.4(RET): c.1900T> C (p.Cys634Arg)single nucleotide variantPathogenicrs75076352GRCh37Chr 10, 43609948: 43609948
7RETNM_020975.4(RET): c.1900T> G (p.Cys634Gly)single nucleotide variantPathogenicrs75076352GRCh37Chr 10, 43609948: 43609948
8RETNM_020975.4(RET): c.1901G> A (p.Cys634Tyr)single nucleotide variantPathogenicrs75996173GRCh37Chr 10, 43609949: 43609949
9RETNM_020630.4(RET): c.1901G> T (p.Cys634Phe)single nucleotide variantPathogenicrs75996173GRCh37Chr 10, 43609949: 43609949
10RETNM_020975.4(RET): c.1900T> C (p.Cys634Arg)single nucleotide variantPathogenicrs75076352GRCh37Chr 10, 43609948: 43609948
11RETNM_020975.4(RET): c.2753T> C (p.Met918Thr)single nucleotide variantPathogenicrs74799832GRCh37Chr 10, 43617416: 43617416
12NM_006891.3(CRYGD): c.43C> T (p.Arg15Cys)single nucleotide variantPathogenicrs121909595GRCh37Chr 2, 208989045: 208989045
13NM_006891.3(CRYGD): c.176G> A (p.Arg59His)single nucleotide variantPathogenicrs121909596GRCh37Chr 2, 208988912: 208988912
14NM_006891.3(CRYGD): c.109C> A (p.Arg37Ser)single nucleotide variantPathogenicrs121909597GRCh37Chr 2, 208988979: 208988979
15NM_006891.3(CRYGD): c.70C> A (p.Pro24Thr)single nucleotide variantPathogenicrs28931605GRCh37Chr 2, 208989018: 208989018
16NM_006891.3(CRYGD): c.470G> A (p.Trp157Ter)single nucleotide variantPathogenicrs121909598GRCh37Chr 2, 208986452: 208986452
17NM_006891.3(CRYGD): c.70C> T (p.Pro24Ser)single nucleotide variantPathogenicrs28931605GRCh37Chr 2, 208989018: 208989018
18SDHBNM_003000.2(SDHB): c.343C> T (p.Arg115Ter)single nucleotide variantPathogenicrs751000085GRCh37Chr 1, 17355175: 17355175
19KIF1BNM_015074.3(KIF1B): c.4442G> A (p.Ser1481Asn)single nucleotide variantPathogenic, risk factorrs121908164GRCh37Chr 1, 10425534: 10425534
20NM_006891.3(CRYGD): c.402C> A (p.Tyr134Ter)single nucleotide variantPathogenicrs398122948GRCh37Chr 2, 208986520: 208986520
21SDHDNM_003002.3(SDHD): c.112C> T (p.Arg38Ter)single nucleotide variantPathogenicrs80338843GRCh37Chr 11, 111958640: 111958640
22SDHDNM_003002.3(SDHD): c.34G> A (p.Gly12Ser)single nucleotide variantPathogenicrs34677591GRCh37Chr 11, 111957665: 111957665
23SDHDNM_003002.3(SDHD): c.242C> T (p.Pro81Leu)single nucleotide variantPathogenicrs80338844GRCh37Chr 11, 111959663: 111959663
24SDHDNM_003002.3(SDHD): c.274G> T (p.Asp92Tyr)single nucleotide variantPathogenicrs80338845GRCh37Chr 11, 111959695: 111959695
25SDHDNM_003002.3(SDHD): c.64C> T (p.Arg22Ter)single nucleotide variantPathogenicrs104894306GRCh37Chr 11, 111958592: 111958592

Expression for genes affiliated with Cataract 4, Multiple Types

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Search GEO for disease gene expression data for Cataract 4, Multiple Types.

Pathways for genes affiliated with Cataract 4, Multiple Types

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GO Terms for genes affiliated with Cataract 4, Multiple Types

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Molecular functions related to Cataract 4, Multiple Types according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1electron carrier activityGO:00090559.5SDHB, SDHD

Sources for Cataract 4, Multiple Types

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet