MCID: CTR027
MIFTS: 19

Cataract-Glaucoma malady

Categories: Rare diseases, Eye diseases, Fetal diseases

Aliases & Classifications for Cataract-Glaucoma

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Sources:
31ICD10 via Orphanet, 48NIH Rare Diseases, 54Orphanet
See all MalaCards sources

Aliases & Descriptions for Cataract-Glaucoma:

Name: Cataract-Glaucoma 48
 
Cataract-Glaucoma Syndrome 54

Characteristics:

Orphanet epidemiological data:

54
cataract-glaucoma syndrome:
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal

Classifications:



External Ids:

Orphanet54 ORPHA162
ICD10 via Orphanet31 Q12.0

Summaries for Cataract-Glaucoma

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MalaCards based summary: Cataract-Glaucoma, also known as cataract-glaucoma syndrome, is related to persistent hyperplastic primary vitreous, autosomal recessive and lowe syndrome. An important gene associated with Cataract-Glaucoma is PITX3 (Paired Like Homeodomain 3). Affiliated tissues include eye, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and reproductive system.

Related Diseases for Cataract-Glaucoma

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Diseases related to Cataract-Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1persistent hyperplastic primary vitreous, autosomal recessive11.1
2lowe syndrome11.0
3armfield x-linked mental retardation syndrome11.0
4fuchs' heterochromic uveitis11.0
5cataract10.4
6pseudopterygium9.9OCRL, PITX3
7leukocyte adhesion deficiency9.8OCRL, PITX3
8senile cataract9.8
9cdkl5-related disorder9.6ATOH7, OCRL, PITX3

Graphical network of diseases related to Cataract-Glaucoma:



Diseases related to cataract-glaucoma

Symptoms & Phenotypes for Cataract-Glaucoma

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GenomeRNAi Phenotypes related to Cataract-Glaucoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-847.3ATOH7, OCRL, OCRL, PITX3, ATOH7, PITX3

MGI Mouse Phenotypes related to Cataract-Glaucoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053899.2ATOH7, OCRL, PITX3
2MP:00053918.5ATOH7, OCRL, PITX3

Drugs & Therapeutics for Cataract-Glaucoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Comparison of Phacotrabeculectomy and Trabeculectomy in the Treatment of Primary Angle-closure Glaucoma (PACG)CompletedNCT01298635
2An Epidemiologic Study of Disease Progression in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration (Proxima A).Active, not recruitingNCT02479386

Search NIH Clinical Center for Cataract-Glaucoma

Genetic Tests for Cataract-Glaucoma

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Anatomical Context for Cataract-Glaucoma

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MalaCards organs/tissues related to Cataract-Glaucoma:

36
Eye

Publications for Cataract-Glaucoma

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Articles related to Cataract-Glaucoma:

(show all 16)
idTitleAuthorsYear
1
Human aqueous humor proteome in cataract, glaucoma and pseudoexfoliation syndrome. (27193151)
2016
2
Combined cataract-glaucoma surgery using the intracanalicular Eyepass glaucoma implant: first clinical results of a prospective pilot study. (18242448)
2008
3
Knowledge about cataract, glaucoma, and age related macular degeneration in the Hong Kong Chinese population. (12234882)
2002
4
Circumferential perilimbal anesthesia for combined cataract glaucoma surgery. (10100254)
1999
5
A prospective randomized comparison of two techniques of combined cataract-glaucoma surgery. (10541897)
1999
6
Cataract, glaucoma and season of birth amongst patients born on the Indian subcontinent. (10218303)
1998
7
A new technique for combined cataract/glaucoma procedures in patients on chronic miotics. (8351096)
1993
8
Combined cataract/glaucoma procedures in patients on chronic miotics. (8259258)
1993
9
Combined cataract-glaucoma surgery using the THC:YAG (holmium) laser ab interno without gonioscopy. (1436972)
1992
10
Combined cataract-glaucoma operation and its complications with the 7-S-intraocular lens. (3595960)
1987
11
The Framingham Eye Study monograph: An ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975. (7444756)
1980
12
Combined simultaneous cataract glaucoma surgery. (360803)
1978
13
Combined cataract-glaucoma operation. (1070879)
1976
14
The partial-punch: a new combined cataract-glaucoma operation. (1264419)
1976
15
A simultaneous cataract-glaucoma operation. (13712279)
1960
16
Miscellaneous ophthalmic surgery, including two techniques of keratoplasty, cataract, glaucoma, keratectomies and muscles. (20261921)
1947

Variations for Cataract-Glaucoma

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Expression for genes affiliated with Cataract-Glaucoma

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Search GEO for disease gene expression data for Cataract-Glaucoma.

Pathways for genes affiliated with Cataract-Glaucoma

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GO Terms for genes affiliated with Cataract-Glaucoma

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Sources for Cataract-Glaucoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet