MCID: CTR027
MIFTS: 21

Cataract-Glaucoma malady

Categories: Rare diseases, Eye diseases, Fetal diseases

Aliases & Classifications for Cataract-Glaucoma

About this section
Sources:
45NIH Rare Diseases, 51Orphanet, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Cataract-Glaucoma:

Name: Cataract-Glaucoma 45
 
Cataract-Glaucoma Syndrome 51

Characteristics:

Orphanet epidemiological data:

51
cataract-glaucoma syndrome:
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal

Classifications:



External Ids:

Orphanet51 162
ICD10 via Orphanet28 Q12.0

Summaries for Cataract-Glaucoma

About this section
MalaCards based summary: Cataract-Glaucoma, also known as cataract-glaucoma syndrome, is related to cataract and persistent hyperplastic primary vitreous, autosomal recessive. An important gene associated with Cataract-Glaucoma is PITX3 (Paired Like Homeodomain 3). Affiliated tissues include eye, lymph node and skeletal muscle, and related mouse phenotypes are reproductive system and vision/eye.

Related Diseases for Cataract-Glaucoma

About this section

Diseases related to Cataract-Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1cataract10.5
2persistent hyperplastic primary vitreous, autosomal recessive10.3
3lowe syndrome10.1
4fuchs' heterochromic uveitis10.1
5senile cataract9.9
6ovarian disease9.5OCRL, PITX3
7cataract-microcephaly-failure to thrive-kyphoscoliosis8.7ATOH7, OCRL, PITX3

Graphical network of diseases related to Cataract-Glaucoma:



Diseases related to cataract-glaucoma

Symptoms for Cataract-Glaucoma

About this section

Drugs & Therapeutics for Cataract-Glaucoma

About this section

Interventional clinical trials:

idNameStatusNCT IDPhase
1Comparison of Phacotrabeculectomy and Trabeculectomy in the Treatment of Primary Angle-closure Glaucoma (PACG)CompletedNCT01298635

Search NIH Clinical Center for Cataract-Glaucoma

Genetic Tests for Cataract-Glaucoma

About this section

Anatomical Context for Cataract-Glaucoma

About this section

MalaCards organs/tissues related to Cataract-Glaucoma:

33
Eye, Lymph node, Skeletal muscle, Skin, Testis

Animal Models for Cataract-Glaucoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Cataract-Glaucoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.9ATOH7, OCRL, PITX3
2MP:00053918.9ATOH7, OCRL, PITX3

Publications for Cataract-Glaucoma

About this section

Articles related to Cataract-Glaucoma:

(show all 16)
idTitleAuthorsYear
1
Human aqueous humor proteome in cataract, glaucoma and pseudoexfoliation syndrome. (27193151)
2016
2
Combined cataract-glaucoma surgery using the intracanalicular Eyepass glaucoma implant: first clinical results of a prospective pilot study. (18242448)
2008
3
Knowledge about cataract, glaucoma, and age related macular degeneration in the Hong Kong Chinese population. (12234882)
2002
4
A prospective randomized comparison of two techniques of combined cataract-glaucoma surgery. (10541897)
1999
5
Circumferential perilimbal anesthesia for combined cataract glaucoma surgery. (10100254)
1999
6
Cataract, glaucoma and season of birth amongst patients born on the Indian subcontinent. (10218303)
1998
7
Combined cataract/glaucoma procedures in patients on chronic miotics. (8259258)
1993
8
A new technique for combined cataract/glaucoma procedures in patients on chronic miotics. (8351096)
1993
9
Combined cataract-glaucoma surgery using the THC:YAG (holmium) laser ab interno without gonioscopy. (1436972)
1992
10
Combined cataract-glaucoma operation and its complications with the 7-S-intraocular lens. (3595960)
1987
11
The Framingham Eye Study monograph: An ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975. (7444756)
1980
12
Combined simultaneous cataract glaucoma surgery. (360803)
1978
13
The partial-punch: a new combined cataract-glaucoma operation. (1264419)
1976
14
Combined cataract-glaucoma operation. (1070879)
1976
15
A simultaneous cataract-glaucoma operation. (13712279)
1960
16
Miscellaneous ophthalmic surgery, including two techniques of keratoplasty, cataract, glaucoma, keratectomies and muscles. (20261921)
1947

Variations for Cataract-Glaucoma

About this section

Expression for genes affiliated with Cataract-Glaucoma

About this section
Search GEO for disease gene expression data for Cataract-Glaucoma.

Pathways for genes affiliated with Cataract-Glaucoma

About this section

GO Terms for genes affiliated with Cataract-Glaucoma

About this section

Sources for Cataract-Glaucoma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet