MCID: CTR039
MIFTS: 26

Cataracts, Autosomal Dominant malady

Genetic diseases, Eye diseases, Rare diseases, Cancer diseases, Fetal diseases, Oral diseases categories

Summaries for Cataracts, Autosomal Dominant

About this section


MalaCards based summary: Cataracts, Autosomal Dominant, also known as cataract, autosomal dominant, is related to cataract and optic atrophy and cataract, autosomal dominant. An important gene associated with Cataracts, Autosomal Dominant is PITX3 (paired-like homeodomain 3). The compound valine have been mentioned in the context of this disorder. Related mouse phenotype vision/eye.

Aliases & Classifications for Cataracts, Autosomal Dominant

About this section
Sources:
21GeneTests, 23GTR, 44Novoseek
See all sources

Cataracts, Autosomal Dominant, Aliases & Descriptions:

Name: Cataracts, Autosomal Dominant 21 23
 
Cataract, Autosomal Dominant 44


Classifications:



Related Diseases for Cataracts, Autosomal Dominant

About this section

Diseases in the Cataract 4, Multiple Types family:

Cataract Cataract Congenital Autosomal Dominant
Cataract, Autosomal Recessive Congenital 2 Cataract, Total Congenital
cataracts, autosomal dominant Cataracts, Autosomal Recessive
Cataract, Autosomal Recessive Congenital 1 Cataract, Autosomal Recessive Congenital 4
Cataract, Autosomal Recessive Congenital 5 Cataract, Autosomal Dominant, Multiple Types 1
Foxe3-Related Cataracts, Autosomal Dominant Cataract 8, Multiple Types
Cataract 6, Multiple Types Cataract 34, Multiple Types
Cataract 1, Multiple Types Cataract 39, Multiple Types, Autosomal Dominant
Cataract 2, Multiple Types Cataract 42
Cataract 18, Autosomal Recessive Cataract 12, Multiple Types
Cataract 20, Multiple Types Cataract 41
Cataract 38, Autosomal Recessive Cataract 26, Multiple Types
Cataract 36 Cataract 11, Multiple Types
Cataract 16, Multiple Types Cataract 15, Multiple Types
Cataract 37, Autosomal Dominant Cataract 14, Multiple Types
Cataract 32, Multiple Types Cataract, Congenital
Cataract 25 Cataract 5, Multiple Types
Cataract 10, Multiple Types Cataract 7
Cataract 19 Cataract 33
Cataract 31, Multiple Types Cataract 9, Multiple Types
Cataract 17, Multiple Types Cataract 3, Multiple Types
Cataract 22, Autosomal Recessive Cataract 23

Diseases related to Cataracts, Autosomal Dominant via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 12)
idRelated DiseaseScoreTop Affiliating Genes
1cataract29.1PITX3, CRYBB2, CRYAA, CRYBB1, GJA8
2optic atrophy and cataract, autosomal dominant10.5
3deafness progressive cataract autosomal dominant10.3
4cataract, autosomal dominant, multiple types 110.3
5optic atrophy 3 with cataract10.3
6foxe3-related cataracts, autosomal dominant10.2
7autosomal dominant childhood-onset cortical cataract10.2
8cerulean cataract10.1
9cataract 4, multiple types9.9CRYAA, GJA8
10microphthalmia9.6CRYAA, PITX3, GJA8
11senile cataract9.4GJA8, CRYBB1, CRYAA, CRYBB2
12cataract, congenital9.2CRYBB2, CRYAA, CRYBB1, GJA8, PITX3

Graphical network of diseases related to Cataracts, Autosomal Dominant:



Diseases related to cataracts, autosomal dominant

Symptoms for Cataracts, Autosomal Dominant

About this section

Drugs & Therapeutics for Cataracts, Autosomal Dominant

About this section

Drug clinical trials:

Search ClinicalTrials for Cataracts, Autosomal Dominant

Search NIH Clinical Center for Cataracts, Autosomal Dominant

Genetic Tests for Cataracts, Autosomal Dominant

About this section

Genetic tests related to Cataracts, Autosomal Dominant:

id Genetic test Affiliating Genes
1 Cataracts, Autosomal Dominant21 23 PITX3
2 Cataract, Autosomal Dominant23

Anatomical Context for Cataracts, Autosomal Dominant

About this section

Animal Models for Cataracts, Autosomal Dominant or affiliated genes

About this section

MGI Mouse Phenotypes related to Cataracts, Autosomal Dominant:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.2GJA8, CRYAA, CRYBB2, PITX3

Publications for Cataracts, Autosomal Dominant

About this section

Variations for Cataracts, Autosomal Dominant

About this section

Expression for genes affiliated with Cataracts, Autosomal Dominant

About this section
Expression patterns in normal tissues for genes affiliated with Cataracts, Autosomal Dominant

Search GEO for disease gene expression data for Cataracts, Autosomal Dominant.

Pathways for genes affiliated with Cataracts, Autosomal Dominant

About this section

Compounds for genes affiliated with Cataracts, Autosomal Dominant

About this section
Sources:
44Novoseek
See all sources

Compounds related to Cataracts, Autosomal Dominant according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1valine449.4GJA8, CRYAA

GO Terms for genes affiliated with Cataracts, Autosomal Dominant

About this section

Biological processes related to Cataracts, Autosomal Dominant according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein homooligomerizationGO:0512609.4GJA8, CRYAA
2lens development in camera-type eyeGO:0020889.2GJA8, PITX3
3visual perceptionGO:0076017.9GJA8, CRYBB1, CRYAA, CRYBB2

Molecular functions related to Cataracts, Autosomal Dominant according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428029.1CRYAA, CRYBB2
2structural constituent of eye lensGO:0052128.2CRYBB1, CRYAA, CRYBB2

Products for genes affiliated with Cataracts, Autosomal Dominant

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Cataracts, Autosomal Dominant

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet