MCID: CSL001
MIFTS: 42

Causalgia malady

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Causalgia

About this section
Sources:
11Disease Ontology, 47NINDS, 13DISEASES, 52Orphanet, 48Novoseek, 37MeSH, 66UMLS, 43NCIt, 29ICD10 via Orphanet, 28ICD10, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Causalgia:

Name: Causalgia 11 47 13 52 48 37 66
Complex Regional Pain Syndrome, Type Ii 11
 
Complex Regional Pain Syndrome Type 2 52
Causalgia Nos 11

Characteristics:

Orphanet epidemiological data:

52
causalgia:
Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:3222
MeSH37 D002422
NCIt43 C121572
Orphanet52 ORPHA99994
ICD10 via Orphanet29 G56.4
ICD1028 G56.4

Summaries for Causalgia

About this section
NINDS:47 Complex regional pain syndrome (CRPS) is a chronic pain condition. The key symptom of CRPS is continuous, intense pain out of proportion to the severity of the injury, which gets worse rather than better over time. CRPS most often affects one of the arms, legs, hands, or feet. Often the pain spreads to include the entire arm or leg. Typical features include dramatic changes in the color and temperature of the skin over the affected limb or body part, accompanied by intense burning pain, skin sensitivity, sweating, and swelling. Doctors aren?t sure what causes CRPS. In some cases the sympathetic nervous system plays an important role in sustaining the pain. Another theory is that CRPS is caused by a triggering of the immune response, which leads to the characteristic inflammatory symptoms of redness, warmth, and swelling in the affected area.

MalaCards based summary: Causalgia, also known as complex regional pain syndrome, type ii, is related to reflex sympathetic dystrophy and congenital absence of both forearm and hand, bilateral, and has symptoms including neuralgia, pain and sciatica. An important gene associated with Causalgia is SCN11A (Sodium Voltage-Gated Channel Alpha Subunit 11), and among its related pathways are L1CAM interactions and Interferon gamma signaling. The drugs tolazoline and tolazoline hydrochloride have been mentioned in the context of this disorder. Affiliated tissues include skin, dorsal root ganglion and cortex.

Wikipedia:69 Complex regional pain syndrome (CRPS), also known as reflex sympathetic dystrophy (RSD), is a long term... more...

Related Diseases for Causalgia

About this section

Diseases related to Causalgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 68)
idRelated DiseaseScoreTop Affiliating Genes
1reflex sympathetic dystrophy10.9
2congenital absence of both forearm and hand, bilateral10.8SCN10A, SCN11A
3erythermalgia, primary10.8SCN10A, SCN11A
4complex regional pain syndrome10.8
5febrile seizures, familial, 110.8SCN10A, SCN11A
6strabismus10.7CALCA, NTRK1
7paroxysmal extreme pain disorder10.7SCN10A, SCN11A
8cataract ataxia deafness10.7CALCA, NPY
9calciphylaxis10.7CALCA, NPS
10neuropathy, hereditary sensory and autonomic, type v10.6NTRK1, SCN10A, SCN11A
11multiple endocrine neoplasia iib10.6CALCA, GDNF, RPIA
12alobar holoprosencephaly10.6CALCA, NPY
13neuropathy, hereditary thermosensitive10.6CALCA, NPS, NPY
14calpainopathy10.6CALCA, TAC1
15hypogonadism cardiomyopathy10.6GDNF, NCAM1
16spinocerebellar ataxia, autosomal recessive 1010.5IFNA2, SCN10A
17medullary thyroid carcinoma, familial10.5CALCA, GDNF, NTRK1
18pearson syndrome10.5CALCA, ENO2
19petrous apex meningioma10.5CALCA, ENO2
20mixed endometrial stromal and smooth muscle tumor10.5CALCA, ENO2
21acute allergic sanguinous otitis media10.5CD27, NCAM1
22norwegian scabies10.4CALCA, ENO2
23pleural cancer10.4ENO2, NCAM1
24malt worker's lung10.4NPY, TAC1
25hilar lung neoplasm10.4ENO2, NCAM1
26skin glomus tumor10.4ENO2, NCAM1
27intussusception10.3CALCA, GDNF, TAC1
28gallbladder signet ring cell adenocarcinoma10.3ENO2, NCAM1
29peripheral focal chorioretinitis10.3NPS, NPY, TAC1
30kleine-levin hibernation syndrome10.3NPS, NPY, TAC1
31schistosomiasis10.2SAMHD1, TAC1
32subpulmonary stenosis10.2ENO2, NCAM1
33nonossifying fibromyxoid tumor10.2ENO2, UBC
34cell type cancer10.2CALCA, ENO2, NCAM1
35endocrine gland cancer10.2CALCA, ENO2, NCAM1
36viral laryngitis10.1NCAM1, PRTN3
37esophagitis10.1ENO2, NCAM1, NTRK1
38papillary serous adenocarcinoma10.1ENO2, NCAM1, NTRK1
39constrictive pericarditis10.1CALCA, NPS, NPY, TAC1
40anal buschke-lowenstein tumor10.1CALCA, CD27, ENO2, NPS
41urethral villous adenoma10.1CALCA, ENO2, TAC1
42hypotrichosis 810.1CALCA, ENO2, NCAM1
43brachyolmia10.1CALCA, ENO2, NCAM1
44akinetic mutism10.1ENO2, NCAM1
45peptic esophagitis10.1IFNA2, PRTN3
46central hypoventilation syndrome, congenital10.1CALCA, GDNF
47pneumonia10.0ENO2, NCAM1
48carcinoma of the vocal tract10.0CALCA, ENO2, IFNA2, NPY
49ovarian clear cell malignant adenofibroma10.0ENO2, NCAM1
50bladder clear cell adenocarcinoma10.0ENO2, NCAM1

Graphical network of the top 20 diseases related to Causalgia:



Diseases related to causalgia

Symptoms for Causalgia

About this section

UMLS symptoms related to Causalgia:


neuralgia, pain, sciatica, chronic pain

Drugs & Therapeutics for Causalgia

About this section

Drugs for Causalgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EtoricoxibPhase 290202409-33-4123619
Synonyms:
202409-33-4
5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl
5-Chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine
5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine
5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine
5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
5CH
AC1L3WZM
Algix
Arcoxia
C11718
C422649
CHEBI:106706
CHEBI:6339
CHEMBL416146
CID123619
D03710
DB01628
DB07166
ETORICOXIB
 
Etoricoxib
Etoricoxib (USAN/INN)
Etoricoxib [USAN:INN:BAN]
Etoricoxibe
Etoricoxibum
FT-0082494
HMS2090A05
L-791456
L001141
L791456
LS-181802
MK 0663
MK 663
MK-0663
MK-663
Merck Sharp & Dohme brand of etoricoxib
MolPort-003-847-339
NCGC00164578-01
Nucoxia
Tauxib
UNII-WRX4NFY03R
ZINC00579472
2
Lidocaine1168137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
╬▒-diethylamino-2,6-dimethylacetanilide
3
Menthol21842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
4parecoxib39198470-84-7

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Restore Claims Characterization StudyCompletedNCT00200122Phase 4
2Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II)RecruitingNCT01392599Phase 3
3Neurotropin to Treat Chronic Neuropathic PainTerminatedNCT00006289Phase 2
4Efficacy of Etoricoxib on Peripheral HyperalgesiaTerminatedNCT01088256Phase 2
5Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.RecruitingNCT02321566Phase 1
6Evoked Fields After Median and Ulnar StimulationCompletedNCT00217243
7The Efficacy of Motor Cortex Stimulation for Pain ControlCompletedNCT00462566
8Dorsal Root Ganglion Stimulation for Hand and Upper Limb PainRecruitingNCT02553876
9Regional Anesthesia Military Battlefield Pain Outcomes StudyActive, not recruitingNCT00431847
10A Safety and Effectiveness Trial of Spinal Cord Stimulation of the Dorsal Root Ganglion for Chronic Lower Limb PainActive, not recruitingNCT01923285
11Efficacy and Safety of a Learning Program of Self- Rehabilitation Exercises by Mirror TherapyNot yet recruitingNCT02667717
12The Effect of Transcranial Direct Current Stimulation (t-DCS) On the P300 Component of Event-Related Potentials in Patients With Chronic Neuropathic Pain Due To CRPS or Diabetic NeuropathyNot yet recruitingNCT00815932
13Efficacy of Parecoxib on Patients With CRPSNo longer availableNCT01523379
14Study of Proteins Associated With Complex Regional Pain SyndromeTerminatedNCT00033969

Search NIH Clinical Center for Causalgia

Inferred drug relations via UMLS66/NDF-RT44:


Cochrane evidence based reviews: causalgia

Genetic Tests for Causalgia

About this section

Anatomical Context for Causalgia

About this section

MalaCards organs/tissues related to Causalgia:

34
Skin, Dorsal root ganglion, Cortex, Spinal cord, Pituitary, Testes, Tongue

Animal Models for Causalgia or affiliated genes

About this section

Publications for Causalgia

About this section

Articles related to Causalgia:

(show top 50)    (show all 186)
idTitleAuthorsYear
1
Surgical relief of causalgia with an artificial nerve guide tube: Successful surgical treatment of causalgia (Complex Regional Pain Syndrome Type II) by in situ tissue engineering with a polyglycolic acid-collagen tube. (16153773)
2005
2
Silas Weir Mitchell, MD: the physician who discovered causalgia. (15043886)
2004
3
Soleus H-reflex tests in causalgia-dystonia compared with dystonia and mimicked dystonic posture. (10599808)
1999
4
Causalgia, pathological pain, and adrenergic receptors. (10393877)
1999
5
Interrupting the sympathetic outflow in causalgia and reflex sympathetic dystrophy. Stellate ganglion blockage: clinics take precautions, but few follow guidelines. (9841007)
1998
6
Traumatic neuralgias: complex regional pain syndromes (reflex sympathetic dystrophy and causalgia): clinical characteristics, pathophysiological mechanisms and therapy. (9767066)
1998
7
Lumbar sympathectomy for causalgia secondary to lumbar laminectomy. (8604835)
1996
8
Intravenous regional guanethidine in the treatment of reflex sympathetic dystrophy/causalgia: a randomized, double-blind study. Guanethidine Study Group. (7574000)
1995
9
Comparison of sympathetic neurons in orofacial and upper extremity nerves: implications for causalgia. (2358949)
1990
10
Sympathectomy for causalgia. Patient selection and long-term results. (3579581)
1987
11
Causalgia: clarifications in terminology and a case presentation. (2426328)
1986
12
Brachial plexus injuries with causalgia resulting from transaxillary rib resection. (4038064)
1985
13
Iatrogenic causalgia. Classification, clinical findings, and legal ramifications. (6466157)
1984
14
Nerve pathophysiology and mechanisms of pain in causalgia. (6192166)
1983
15
Chronic epidural dorsal column stimulation in the treatment of causalgia pain. (6977321)
1982
16
Dental causalgia. (6942435)
1981
17
Of cardiac causalgia, Horner's syndrome, and the cardiac dermatome. (7446399)
1980
18
Deafferentation and causalgia. (6988923)
1980
19
Horner syndrome with causalgia. (7189258)
1980
20
The use of temperature biofeedback in the treatment of chronic pain due to causalgia. (476193)
1979
21
Causalgia. (710015)
1978
22
Pain mechanisma in causalgia. (932766)
1976
23
Management of post-traumatic pain syndromes (causalgia). (1163901)
1975
24
Cardiac causalgia and hoarseness. (5075649)
1972
25
Treatment of causalgia. Review of cases at Brooke General Hospital. (5540106)
1971
26
Causalgia. (5410601)
1970
27
Cardiac causalgia. (5721829)
1968
28
Causalgia. A centennial review. (5336504)
1967
29
Causalgia. (14484081)
1961
30
Causalgia. (13458747)
1957
31
Causalgia treated with chlorpromazine hydrochloride. (13271129)
1955
32
Causalgia: a review of 48 cases. (13223107)
1954
33
Causalgia pathogenesis and treatment. (13009495)
1952
34
The physiology of pain: abnormal neuron states in causalgia and related phenomena. (14799892)
1951
35
Causalgia. (18142024)
1949
36
Causalgia; a review of 22 cases. (18100509)
1948
37
Causalgia; a review. (18105061)
1948
38
Causalgia; the signs and symptoms, with particular reference to vasomotor disturbances. (18905118)
1948
39
Causalgia. (18884125)
1948
40
Causalgia Following Gunshot Injuries of Nerves : Role of Emotional Stimuli and Surgical Cure through Interruption of Diencephalic Efferent Discharge by Sympathectomy. (17859188)
1948
41
The visious circle in causalgia. (18886383)
1948
42
Causalgia of the face; two cases successfully treated by sympathectomy. (20240904)
1947
43
On the pathogenesis of causalgia in peripheral nerve injuries. (20261818)
1947
44
Causalgia of the face. (20340570)
1947
45
Causalgia secondary to injury of the major peripheral nerves; treatment by sympathectomy. (21020294)
1946
46
Treatment of causalgia; an analysis of loo cases. (21018506)
1946
47
A method for the chemical production of a prolonged sympathetic paralysis; report of its use in two patients with causalgia. (20997877)
1946
48
Pain after amputation; simple stump pain; phantome sensation; causalgia. (21011871)
1945
49
Genitofemoral Causalgia : (A New Syndrome). (20322413)
1942
50
Short Notes and Clinical Cases: ERYTHROMELALGIA, CAUSALGIA, AND ALLIED CONDITIONS. (21611486)
1922

Variations for Causalgia

About this section

Expression for genes affiliated with Causalgia

About this section
Search GEO for disease gene expression data for Causalgia.

Pathways for genes affiliated with Causalgia

About this section

Pathways related to Causalgia according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.7NCAM1, SCN10A, SCN11A
2
Show member pathways
9.0IFNA2, NCAM1, SAMHD1, UBC
38.4CALCA, ENO2, NCAM1, NPY, NTRK1, SCN10A

GO Terms for genes affiliated with Causalgia

About this section

Cellular components related to Causalgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1voltage-gated sodium channel complexGO:000151810.7SCN10A, SCN11A
2axonGO:00304249.4CALCA, NTRK1, SCN11A, TAC1
3extracellular spaceGO:00056157.3CALCA, ENO2, IFNA2, NPY, PRTN3, TAC1

Biological processes related to Causalgia according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1detection of temperature stimulus involved in sensory perception of painGO:005096510.4CALCA, NTRK1
2sympathetic nervous system developmentGO:004848510.4GDNF, NTRK1
3positive regulation of action potentialGO:004576010.3NPS, TAC1
4positive regulation of synaptic transmission, GABAergicGO:003223010.2NPS, TAC1
5positive regulation of ossificationGO:004577810.2CALCA, TAC1
6positive regulation of synaptic transmission, glutamatergicGO:005196810.0NPS, NTRK1
7response to painGO:00482659.8CALCA, TAC1
8sensory perception of painGO:00192339.4NTRK1, SCN10A, TAC1
9neuropeptide signaling pathwayGO:00072189.4CALCA, NPS, NPY, TAC1
10cellular response to nerve growth factor stimulusGO:19900909.3CALCA, NTRK1, TAC1

Molecular functions related to Causalgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1voltage-gated sodium channel activityGO:000524810.1SCN10A, SCN11A

Sources for Causalgia

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet