MCID: CSL001
MIFTS: 42

Causalgia malady

Neuronal diseases, Rare diseases categories

Aliases & Classifications for Causalgia

About this section
Sources:
10Disease Ontology, 46NINDS, 47Novoseek, 12DISEASES, 51Orphanet, 65UMLS, 36MeSH, 59SNOMED-CT, 28ICD10 via Orphanet, 27ICD10
See all sources

Aliases & Descriptions for Causalgia:

Name: Causalgia 10 46 47 12 51 65 36
Complex Regional Pain Syndrome, Type Ii 10
 
Complex Regional Pain Syndrome Type 2 51
Causalgia Nos 10


Classifications:



Characteristics (Orphanet epidemiological data):

51
causalgia:
Age of onset: All ages


External Ids:

Disease Ontology10 DOID:3222
MeSH36 D002422
Orphanet51 99994
ICD10 via Orphanet28 G56.4
ICD1027 G56.4

Summaries for Causalgia

About this section
NINDS:46 Complex regional pain syndrome (CRPS) is a chronic pain condition. The key symptom of CRPS is continuous, intense pain out of proportion to the severity of the injury, which gets worse rather than better over time. CRPS most often affects one of the arms, legs, hands, or feet. Often the pain spreads to include the entire arm or leg. Typical features include dramatic changes in the color and temperature of the skin over the affected limb or body part, accompanied by intense burning pain, skin sensitivity, sweating, and swelling. Doctors aren?t sure what causes CRPS. In some cases the sympathetic nervous system plays an important role in sustaining the pain. Another theory is that CRPS is caused by a triggering of the immune response, which leads to the characteristic inflammatory symptoms of redness, warmth, and swelling in the affected area.

MalaCards based summary: Causalgia, also known as complex regional pain syndrome, type ii, is related to burns and neuromuscular disease. An important gene associated with Causalgia is CALCA (Calcitonin-Related Polypeptide Alpha), and among its related pathways are NK1R-mediated Non-Apoptotic PCD and Neuroscience. The drugs tolazoline and tolazoline hydrochloride have been mentioned in the context of this disorder. Affiliated tissues include skin, spinal cord and pituitary, and related mouse phenotype behavior/neurological.

Wikipedia:68 Complex regional pain syndrome (CRPS) formerly reflex sympathetic dystrophy (RSD), \"causalgia\", or... more...

Related Diseases for Causalgia

About this section

Diseases related to Causalgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 71)
idRelated DiseaseScoreTop Affiliating Genes
1burns30.6CALCA, TAC1
2neuromuscular disease30.5CALCA, ENO2, GDNF, SCN10A
3reflex sympathetic dystrophy10.7
4complex regional pain syndrome10.6
5familial ocular anterior segment mesenchymal dysgenesis10.3SCN10A, SCN11A
6primary microcephaly-epilepsy-permanent neonatal diabetes syndrome10.3SCN10A, SCN11A
7myopathy with hexagonally cross-linked tubular arrays10.3CALCA, NPY
8episodic pain syndrome, familial10.3SCN10A, SCN11A
9autonomic peripheral neuropathy10.3
10amenorrhea10.3
11pain disorder10.3
12autonomic nervous system disease10.3
13muscular dystrophy10.3
14nervous system disease10.3
15peripheral nervous system disease10.3
16peripheral neuropathy10.3
17skin tag10.3
18vein disease10.3
19neurologic diseases10.3
20chiari malformation type 210.3
21dysautonomia like disorder10.3
22autonomic dysfunction10.3
23complex regional pain syndrome type 110.3
24hypertensive retinopathy10.2CALCA, NPS, NPY
25paroxysmal extreme pain disorder10.2SCN10A, SCN11A
26hypogonadism cardiomyopathy10.2GDNF, NCAM1
27medullary thyroid carcinoma, familial10.2CALCA, GDNF, NTRK1
28root caries10.2NPS, TAC1
29neuronitis10.2
30dystonia10.2
31nasal cavity carcinoma in situ10.2CALCA, ENO2
32paroxysmal nocturnal hemoglobinuria10.2CALCA, ENO2
33lobar holoprosencephaly10.2CALCA, NPY
34cluttering10.2CALCA, NPY
35brachydactyly - preaxial hallux varus10.2TAC1, TACR1
36selective iga deficiency disease10.2CALCA, ENO2
37fragile x-associated tremor/ataxia syndrome10.2ENO2, NCAM1
38cavernous sinus meningioma10.1ENO2, NCAM1
39lymph node palisaded myofibroblastoma10.1ENO2, UBC
40monocular exotropia10.1NPS, NPY, TAC1
41gangliocytoma10.1ENO2, NCAM1
42acute thyroiditis10.1NPY, TAC1
43extrahepatic bile duct adenoma10.1ENO2, NCAM1
44riedel's fibrosing thyroiditis10.1CALCA, ENO2, IFNA2
45ampulla of vater small cell carcinoma10.1CALCA, NCAM1, ZNF135
46brachyolmia10.1CALCA, ENO2, NCAM1
47subpulmonary stenosis10.1ENO2, NCAM1
48autonomic nervous system neoplasm10.1CALCA, NPS, NPY, TAC1
49extramedullary plasmacytoma10.1CD27, NCAM1
50immune-complex glomerulonephritis10.1CALCA, NPS

Graphical network of the top 20 diseases related to Causalgia:



Diseases related to causalgia

Symptoms for Causalgia

About this section

Drugs & Therapeutics for Causalgia

About this section

Drugs for Causalgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Etoricoxibapproved, investigationalPhase 288202409-33-4123619
Synonyms:
202409-33-4
5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl
5-Chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine
5-chloro-2-(6-Methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine
5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
5-chloro-6'-Methyl-3-(P-(methylsulfonyl)phenyl)-2,3'-bipyridine
5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
5CH
AC1L3WZM
Algix
Arcoxia
C11718
C422649
CHEBI:106706
CHEBI:6339
CHEMBL416146
CID123619
D03710
DB01628
DB07166
ETORICOXIB
 
Etoricoxib
Etoricoxib (USAN/INN)
Etoricoxib [USAN:INN:BAN]
Etoricoxibe
Etoricoxibum
FT-0082494
HMS2090A05
L-791456
L001141
L791456
LS-181802
MK 0663
MK 663
MK-0663
MK-663
Merck Sharp & Dohme brand of etoricoxib
MolPort-003-847-339
NCGC00164578-01
Nucoxia
Tauxib
UNII-WRX4NFY03R
ZINC00579472
2Cyclooxygenase 2 InhibitorsPhase 2517
3NeurotropinPhase 23
4
Lidocaineapproved991137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Afterburn
Akten
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bikini Zone Medicated
Bikini Zone Medicated Creme
Bio-0767
Bio-scriptives Lidum
Bio-scriptives Lidum Hemorroidal (anorectal)
Bio-scriptives Lidum Topical Analgesic
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
Burn Relief Leader
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Comfortcaine
Cuivasil
Curacaine Transdermal Corporation
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
Derma Numb
DermaFlex
Desert Harvest Releveum
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Dr. Numb
Dr. Richs Numbing
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gigi Anesthetic Numbing
Gravocain
H-releve Hemorrhoidal
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
Hawaiian Tropic
Hush Anesthetic
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
LS-805
Lanabiotic
 
Laryng-o-jet
Leostesin
Lida-Mantle
Lidall
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine 4% Cream
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Hydrochloride
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocaine hydrochloride
Lidocainum
Lidocainum [INN-Latin]
Lidocare Mist
Lidocaton
Lidocream 4
Lidocream 5
Lidoderm
Lidoderm 5
Lidoject-1
Lidoject-2
Lifestyles Epic Male Genital Desensitizer
Lignocaine
Lignocainum
Lingocaine
Lmx4
Lmx5
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Numb Master Topical Anesthetic
Numb Nuts
Ocean Potion Instant Burn Relief Ice
Octocaine
Octocaine-100
Octocaine-50
Plum Smooth Plumb Numb Gelee
Premjact Male Desensitizer Pound International
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Recticare
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Simplicity Desensitizing
Simply Numb Endure
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Sole Serum
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Walgreens Aloe Vera Pain Relieving
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocaine-mpf
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zcaine Fast Acting Anesthetic
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
╬▒-diethylamino-2,6-dimethylacetanilide
5parecoxibexperimental37119828

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Restore Claims Characterization StudyCompletedNCT00200122Phase 4
2Surgical Treatment Of Complex Regional Pain Syndrome Type II (CRPS II)RecruitingNCT01392599Phase 3
3Efficacy of Etoricoxib on Peripheral HyperalgesiaTerminatedNCT01088256Phase 2
4Neurotropin to Treat Chronic Neuropathic PainTerminatedNCT00006289Phase 2
5Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.RecruitingNCT02321566Phase 1
6The Efficacy of Motor Cortex Stimulation for Pain ControlCompletedNCT00462566
7Evoked Fields After Median and Ulnar StimulationCompletedNCT00217243
8Dorsal Root Ganglion Stimulation for Hand and Upper Limb PainRecruitingNCT02553876
9Regional Anesthesia Military Battlefield Pain Outcomes StudyActive, not recruitingNCT00431847
10A Safety and Effectiveness Trial of Spinal Cord Stimulation of the Dorsal Root Ganglion for Chronic Lower Limb PainActive, not recruitingNCT01923285
11Efficacy and Safety of a Learning Program of Self- Rehabilitation Exercises by Mirror TherapyNot yet recruitingNCT02667717
12The Effect of Transcranial Direct Current Stimulation (t-DCS) On the P300 Component of Event-Related Potentials in Patients With Chronic Neuropathic Pain Due To CRPS or Diabetic NeuropathyNot yet recruitingNCT00815932
13Efficacy of Parecoxib on Patients With CRPSNo longer availableNCT01523379
14Study of Proteins Associated With Complex Regional Pain SyndromeTerminatedNCT00033969

Search NIH Clinical Center for Causalgia

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: Causalgia

Genetic Tests for Causalgia

About this section

Anatomical Context for Causalgia

About this section

MalaCards organs/tissues related to Causalgia:

33
Skin, Spinal cord, Pituitary, Tongue, Testes, Dorsal root ganglion

Animal Models for Causalgia or affiliated genes

About this section

MGI Mouse Phenotypes related to Causalgia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053867.4CALCA, ENO2, GDNF, NCAM1, NPY, NTRK1

Publications for Causalgia

About this section

Articles related to Causalgia:

(show top 50)    (show all 185)
idTitleAuthorsYear
1
From Mitchell's causalgia to complex regional pain syndromes: 150 years of definitions and theories. (25786040)
2015
2
Causalgia: a restatement. (19927072)
2009
3
Silas Weir Mitchell, MD: the physician who discovered causalgia. (15043886)
2004
4
Great auricular causalgia: an unusual complication of excision of the submandibular gland. (14581027)
2003
5
Complex regional pain syndrome (type I, RSD; type II, causalgia): controversies. (10870738)
2000
6
Venipuncture-induced causalgia: anatomic relations of upper extremity superficial veins and nerves, and clinical considerations. (10988302)
2000
7
Soleus H-reflex tests in causalgia-dystonia compared with dystonia and mimicked dystonic posture. (10599808)
1999
8
Interrupting the sympathetic outflow in causalgia and reflex sympathetic dystrophy. Intravenous regional guanethidine blockage is a safe and effective treatment. (9841006)
1998
9
Interrupting the sympathetic outflow in causalgia and reflex sympathetic dystrophy. Stellate ganglion blockage: clinics take precautions, but few follow guidelines. (9841007)
1998
10
Traumatic neuralgias: complex regional pain syndromes (reflex sympathetic dystrophy and causalgia): clinical characteristics, pathophysiological mechanisms and therapy. (9767066)
1998
11
Complex regional pain syndrome (reflex sympathetic dystrophy and causalgia): management with the calcium channel blocker nifedipine and/or the alpha-sympathetic blocker phenoxybenzamine in 59 patients. (9107464)
1997
12
Lumbar sympathectomy for causalgia secondary to lumbar laminectomy. (8604835)
1996
13
Reflex sympathetic dystrophy/sympathetically maintained pain/causalgia: the syndrome of neuropathic pain with dysautonomia. (7701127)
1994
14
Comparison of sympathetic neurons in orofacial and upper extremity nerves: implications for causalgia. (2358949)
1990
15
Comment on Hopkins and Charters, 'An unusual case of causalgia. Relevance to recent hypothesis on mechanism of causalgia' (Pain, 37 (1989) 93-95) (2326100)
1990
16
T2-ganglionectomy via limited costotransversectomy for minor causalgia. (2353271)
1990
17
Burning and pain after injury. Is it causalgia or reflex sympathetic dystrophy? (3340606)
1988
18
Induction of involuntary movements by peripheral trauma: an analogy with causalgia. (2876186)
1986
19
Causalgia as a complication of meningococcal meningitis. (3089364)
1986
20
Causalgia: clarifications in terminology and a case presentation. (2426328)
1986
21
Brachial plexus injuries with causalgia resulting from transaxillary rib resection. (4038064)
1985
22
Intrafascicular decompression in the treatment of causalgia with special reference to the mechanism. (3880194)
1985
23
Dental causalgia. (6942435)
1981
24
Of cardiac causalgia, Horner's syndrome, and the cardiac dermatome. (7446399)
1980
25
Facial causalgia: report of case. (6932491)
1980
26
The use of temperature biofeedback in the treatment of chronic pain due to causalgia. (476193)
1979
27
Phantom tongue pain and causalgia: case presentation and treatment. (573572)
1979
28
The causalgia syndrome treated with regional intravenous guanethidine. (756012)
1978
29
Causalgia. (710015)
1978
30
Causalgia and other reflex sympathetic dystrophies. (4701608)
1973
31
Causalgia. (4113066)
1972
32
Causalgia. (5539173)
1971
33
"Minor" causalgia. (5444499)
1970
34
Causalgia. (5359635)
1969
35
Causalgia. A case report. (13900497)
1961
36
Causalgia: a review of 48 cases. (13223107)
1954
37
Causalgia pathogenesis and treatment. (13009495)
1952
38
The physiology of pain: abnormal neuron states in causalgia and related phenomena. (14799892)
1951
39
Causalgia. (18142024)
1949
40
Visceral denervation in the control of functional abdominal pain, biliary dyskinesia, chronic pancreatitis, intractable abdominal pain of organic origin and the pain due to adhesion causalgia. (15394117)
1949
41
Causalgia; a review of 22 cases. (18100509)
1948
42
Raynaud's Phenomenon and Atypical Causalgia; the Role of Sympathectomy. (17859117)
1948
43
Causalgia; a review. (18105061)
1948
44
Causalgia; the signs and symptoms, with particular reference to vasomotor disturbances. (18905118)
1948
45
Causalgia. (20270272)
1947
46
Causalgia of the face. (20344337)
1947
47
Causalgia. (20270995)
1947
48
Causalgia; its etiology, diagnosis and treatment with tetra-ethyl-ammonium chloride (etamon chloride). (20267441)
1947
49
Genitofemoral Causalgia. (20323539)
1945
50
Genitofemoral Causalgia : (A New Syndrome). (20322413)
1942

Variations for Causalgia

About this section

Expression for genes affiliated with Causalgia

About this section
Search GEO for disease gene expression data for Causalgia.

Pathways for genes affiliated with Causalgia

About this section

Pathways related to Causalgia according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6TAC1, TACR1
28.5CALCA, ENO2, NCAM1, NPY, NTRK1, SCN10A

GO Terms for genes affiliated with Causalgia

About this section

Cellular components related to Causalgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1voltage-gated sodium channel complexGO:000151810.7SCN10A, SCN11A
2axonGO:00304249.4CALCA, NCAM1, NTRK1, SCN11A, TAC1
3neuronal cell bodyGO:00430259.0CALCA, ENO2, NCAM1, NTRK1, TAC1
4extracellular spaceGO:00056157.8CALCA, ENO2, IFNA2, NPY, PRTN3, TAC1
5plasma membraneGO:00058865.5CD27, ENO2, MGAM, MRAS, NCAM1, NTRK1

Biological processes related to Causalgia according to GeneCards Suite gene sharing:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1sympathetic nervous system developmentGO:004848510.6GDNF, NTRK1
2positive regulation of synaptic transmission, glutamatergicGO:005196810.6NPS, NTRK1
3detection of temperature stimulus involved in sensory perception of painGO:005096510.5CALCA, NTRK1
4positive regulation of synaptic transmission, GABAergicGO:003223010.5NPS, TAC1
5positive regulation of action potentialGO:004576010.5NPS, TAC1
6positive regulation of ossificationGO:004577810.4CALCA, TAC1
7tachykinin receptor signaling pathwayGO:000721710.2TAC1, TACR1
8detection of abiotic stimulusGO:000958210.2TAC1, TACR1
9cellular response to nerve growth factor stimulusGO:199009010.1CALCA, NTRK1, TAC1
10response to yeastGO:000187810.1CALCA, NPY, TAC1
11antifungal humoral responseGO:001973210.1CALCA, NPY, TAC1
12defense response to Gram-negative bacteriumGO:005082910.1CALCA, NPY, TAC1
13sensory perception of painGO:001923310.0NTRK1, SCN10A, TAC1
14regulation of blood pressureGO:000821710.0CALCA, NPY, TAC1
15antibacterial humoral responseGO:00197319.9CALCA, NPY, TAC1
16defense response to Gram-positive bacteriumGO:00508309.9CALCA, NPY, TAC1
17response to painGO:00482659.8CALCA, TAC1, TACR1
18neuropeptide signaling pathwayGO:00072189.3CALCA, NPS, NPY, TAC1, TACR1
19Ras protein signal transductionGO:00072659.3MRAS, NCAM1, NTRK1, UBC
20neuron projection developmentGO:00311759.3GDNF, NCAM1, NPY
21inflammatory responseGO:00069549.2CALCA, CD27, IFNA2, TAC1, TACR1
22cell surface receptor signaling pathwayGO:00071669.2CD27, IFNA2, NCAM1, TACR1, UBC
23innate immune responseGO:00450878.6CALCA, IFNA2, NCAM1, NPY, TAC1, UBC

Molecular functions related to Causalgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1voltage-gated sodium channel activityGO:000524810.1SCN10A, SCN11A

Sources for Causalgia

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet