MCID: CNT033
MIFTS: 37

Central Nervous System Cancer malady

Cancer diseases, Neuronal diseases categories
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Summaries for Central Nervous System Cancer

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Disease Ontology:8 A nervous system cancer that is located in the central nervous system.

MalaCards based summary: Central Nervous System Cancer, also known as neoplasm of central nervous system, is related to central nervous system hematologic cancer and nervous system cancer. An important gene associated with Central Nervous System Cancer is ARSA (arylsulfatase A), and among its related pathways is Metabolism. The drug carboplatin and the compounds ganglioside and glutamine have been mentioned in the context of this disorder. Affiliated tissues include the central nervous system and brain.

Aliases & Classifications for Central Nervous System Cancer

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 39NCIt, 57SNOMED-CT, 34MeSH
See all sources

Central Nervous System Cancer, Aliases & Descriptions:

Name: Central Nervous System Cancer 8 10 44
Neoplasm of Central Nervous System 8 62
Malignant Tumor of Cns 8 62
Malignant Neoplasm of Central Nervous System, Nos 8
Malignant Neoplasm of Central Nervous System 62
 
Central Nervous System Neoplasms 62
Central Nervous System Tumors 8
Central Nervous System Tumor 8
Cns Neoplasm 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


External Ids:

Disease Ontology8 DOID:3620
NCIt39 C9293
MeSH34 D016543

Related Diseases for Central Nervous System Cancer

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Diseases in the Central Nervous System Cancer family:

Nervous System Cancer

Diseases related to Central Nervous System Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 20)
idRelated DiseaseScoreTop Affiliating Genes
1central nervous system hematologic cancer30.2ARSA, ENO2
2nervous system cancer10.7
3endotheliitis10.4
4leukemia10.3
5malignant glioma10.2
6hyperprolactinemia10.2
7neuronitis10.2
8childhood leukemia10.2
9meningitis10.2
10oligodendroglioma10.2
11mowat-wilson syndrome10.2
12turcot syndrome10.2
13astrocytoma10.1
14brain cancer10.1
15brucellosis10.1
16medulloblastoma10.1
17meningioma10.1
18spinal cancer10.1
19cerebral amyloid angiopathy10.0
20cerebritis10.0

Graphical network of diseases related to Central Nervous System Cancer:



Diseases related to central nervous system cancer

Symptoms for Central Nervous System Cancer

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Drugs & Therapeutics for Central Nervous System Cancer

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Drug clinical trials:

Search ClinicalTrials for Central Nervous System Cancer

Search NIH Clinical Center for Central Nervous System Cancer

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Central Nervous System Cancer

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Anatomical Context for Central Nervous System Cancer

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MalaCards organs/tissues related to Central Nervous System Cancer:

32
Brain

FMA organs/tissues related to Central Nervous System Cancer:

14
The central nervous system

Animal Models for Central Nervous System Cancer or affiliated genes

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Publications for Central Nervous System Cancer

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Articles related to Central Nervous System Cancer:

(show all 13)
idTitleAuthorsYear
1
Vocational identity, positive affect, and career thoughts in a group of young adult central nervous system cancer survivors. (25035908)
2014
2
Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients. (23661397)
2013
3
Medulloblastoma and Brucellosis - Molecular Evidence of Brucella sp in Association with Central Nervous System Cancer. (21475718)
2011
4
Comparison of time trends in brain and central nervous system cancer mortality (1990-2006) between countries based on the WHO mortality database. (21273379)
2011
5
Long-term health experience of jet engine manufacturing workers: IV. A comparison of central nervous system cancer ascertainment using mortality and incidence data. (20816315)
2010
6
Pain in children with central nervous system cancer: a review of the literature. (20591796)
2010
7
School-aged children after the end of successful treatment of non-central nervous system cancer: longitudinal assessment of health-related quality of life, anxiety and coping. (19594611)
2009
8
Comparison of time trends in brain central nervous system cancer incidence (1973-97) in East Asia, Europe and USA, from Cancer Incidence in Five Continents Vols IV-VIII. (18772173)
2008
9
Neuropsychological sequelae of non-central nervous system cancer and cancer therapy. (18415683)
2008
10
Cytotoxicity and oncostatic activity of the thiazolidinedione derivative CGP 52608 on central nervous system cancer cells. (15194216)
2004
11
Exploitation of immune mechanisms in the treatment of central nervous system cancer. (10914414)
2000
12
Human malignant astrocytoma xenografts migrate in rat brain: a model for central nervous system cancer research. (2651679)
1989
13
Brain and central nervous system cancer mortality in U. S. rubber workers. (6953785)
1982

Variations for Central Nervous System Cancer

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Expression for genes affiliated with Central Nervous System Cancer

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Expression patterns in normal tissues for genes affiliated with Central Nervous System Cancer

Search GEO for disease gene expression data for Central Nervous System Cancer.

Pathways for genes affiliated with Central Nervous System Cancer

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Pathways related to Central Nervous System Cancer according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1ARSA, ENO2

Compounds for genes affiliated with Central Nervous System Cancer

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Sources:
44Novoseek, 24HMDB, 11DrugBank
See all sources

Compounds related to Central Nervous System Cancer according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1ganglioside449.4ARSA, ENO2
2glutamine449.4ARSA, ENO2
3lactate449.3ENO2, ARSA
4creatinine449.3ARSA, ENO2
5aspartate449.3ENO2, ARSA
6leucine449.2ENO2, ARSA
7magnesium44 24 1111.2ARSA, ENO2
8Water249.1ARSA, ENO2
9tyrosine449.1ARSA, ENO2
10alanine449.0ENO2, ARSA
11lipid448.8ARSA, ENO2

GO Terms for genes affiliated with Central Nervous System Cancer

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Cellular components related to Central Nervous System Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056159.1ARSA, ENO2

Biological processes related to Central Nervous System Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:0442819.1ARSA, ENO2

Products for genes affiliated with Central Nervous System Cancer

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  • Antibodies
  • Proteins
  • Lysates

Sources for Central Nervous System Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet