MCID: CNT033
MIFTS: 30

Central Nervous System Cancer malady

Neuronal diseases, Cancer diseases categories

Summaries for Central Nervous System Cancer

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Disease Ontology:9 A nervous system cancer that is located in the central nervous system.

MalaCards based summary: Central Nervous System Cancer, also known as malignant neoplasm of central nervous system, nos, is related to nervous system cancer and endotheliitis. An important gene associated with Central Nervous System Cancer is ARSA (arylsulfatase A), and among its related pathways is Metabolism. The drug carboplatin and the compounds ganglioside and glutamine have been mentioned in the context of this disorder. Affiliated tissues include the central nervous system and brain.

Aliases & Classifications for Central Nervous System Cancer

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 55SNOMED-CT, 33MeSH, 38NCIt
See all sources

Central Nervous System Cancer, Aliases & Descriptions:

Name: Central Nervous System Cancer 9 11 43
Malignant Neoplasm of Central Nervous System, Nos 9
Malignant Neoplasm of Central Nervous System 60
Neoplasm of Central Nervous System 9
Central Nervous System Neoplasms 60
 
Central Nervous System Tumors 9
Central Nervous System Tumor 9
Malignant Tumor of Cns 9
Cns Neoplasm 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


External Ids:

Disease Ontology9 DOID:3620
MeSH33 D016543
NCIt38 C9293

Related Diseases for Central Nervous System Cancer

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Diseases in the Nervous System Cancer family:

central nervous system cancer

Diseases related to Central Nervous System Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
idRelated DiseaseScoreTop Affiliating Genes
1nervous system cancer10.7
2endotheliitis10.4
3insulin-like growth factor i10.3
4leukemia10.3
5medulloblastoma10.2
6meningioma, familial10.2
7astrocytoma10.2
8brain cancer10.2
9brucellosis10.2
10spinal cancer10.2
11mismatch repair cancer syndrome10.2
12mowat-wilson syndrome10.2
13hyperprolactinemia10.2
14schwannomatosis10.2
15malignant glioma10.2
16neuronitis10.2
17tuberous sclerosis10.2
18childhood leukemia10.2
19facial paralysis10.2
20meningitis10.2
21oligodendroglioma10.2
22cerebral amyloid angiopathy10.0
23cerebritis10.0

Graphical network of the top 20 diseases related to Central Nervous System Cancer:



Diseases related to central nervous system cancer

Symptoms for Central Nervous System Cancer

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Drugs & Therapeutics for Central Nervous System Cancer

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Drug clinical trials:

Search ClinicalTrials for Central Nervous System Cancer

Search NIH Clinical Center for Central Nervous System Cancer

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Central Nervous System Cancer

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Anatomical Context for Central Nervous System Cancer

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MalaCards organs/tissues related to Central Nervous System Cancer:

31
Brain

FMA organs/tissues related to Central Nervous System Cancer:

14
The central nervous system

Animal Models for Central Nervous System Cancer or affiliated genes

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Publications for Central Nervous System Cancer

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Articles related to Central Nervous System Cancer:

(show all 14)
idTitleAuthorsYear
1
Brain and central nervous system cancer incidence in navarre (Spain), 1973-2008 and projections for 2014. (25561983)
2015
2
Vocational identity, positive affect, and career thoughts in a group of young adult central nervous system cancer survivors. (25035908)
2014
3
Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients. (23661397)
2013
4
Medulloblastoma and Brucellosis - Molecular Evidence of Brucella sp in Association with Central Nervous System Cancer. (21475718)
2011
5
Comparison of time trends in brain and central nervous system cancer mortality (1990-2006) between countries based on the WHO mortality database. (21273379)
2011
6
Long-term health experience of jet engine manufacturing workers: IV. A comparison of central nervous system cancer ascertainment using mortality and incidence data. (20816315)
2010
7
Pain in children with central nervous system cancer: a review of the literature. (20591796)
2010
8
School-aged children after the end of successful treatment of non-central nervous system cancer: longitudinal assessment of health-related quality of life, anxiety and coping. (19594611)
2009
9
Comparison of time trends in brain central nervous system cancer incidence (1973-97) in East Asia, Europe and USA, from Cancer Incidence in Five Continents Vols IV-VIII. (18772173)
2008
10
Neuropsychological sequelae of non-central nervous system cancer and cancer therapy. (18415683)
2008
11
Cytotoxicity and oncostatic activity of the thiazolidinedione derivative CGP 52608 on central nervous system cancer cells. (15194216)
2004
12
Exploitation of immune mechanisms in the treatment of central nervous system cancer. (10914414)
2000
13
Human malignant astrocytoma xenografts migrate in rat brain: a model for central nervous system cancer research. (2651679)
1989
14
Brain and central nervous system cancer mortality in U. S. rubber workers. (6953785)
1982

Variations for Central Nervous System Cancer

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Expression for genes affiliated with Central Nervous System Cancer

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Search GEO for disease gene expression data for Central Nervous System Cancer.

Pathways for genes affiliated with Central Nervous System Cancer

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Pathways related to Central Nervous System Cancer according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1ARSA, ENO2

Compounds for genes affiliated with Central Nervous System Cancer

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Sources:
43Novoseek, 24HMDB, 12DrugBank
See all sources

Compounds related to Central Nervous System Cancer according to GeneCards Suite gene sharing:

(show all 11)
idCompoundScoreTop Affiliating Genes
1ganglioside439.4ARSA, ENO2
2glutamine439.4ARSA, ENO2
3lactate439.3ENO2, ARSA
4creatinine439.3ARSA, ENO2
5aspartate439.3ENO2, ARSA
6leucine439.2ENO2, ARSA
7magnesium43 24 1211.2ARSA, ENO2
8Water249.1ARSA, ENO2
9tyrosine439.1ARSA, ENO2
10alanine439.0ENO2, ARSA
11lipid438.8ARSA, ENO2

GO Terms for genes affiliated with Central Nervous System Cancer

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Cellular components related to Central Nervous System Cancer according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056159.1ARSA, ENO2

Biological processes related to Central Nervous System Cancer according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:00442819.1ARSA, ENO2

Products for genes affiliated with Central Nervous System Cancer

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Central Nervous System Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet