MCID: CNT018
MIFTS: 37

Central Nervous System Leukemia

Categories: Cancer diseases, Immune diseases, Neuronal diseases

Aliases & Classifications for Central Nervous System Leukemia

MalaCards integrated aliases for Central Nervous System Leukemia:

Name: Central Nervous System Leukemia 12 14 69
Leukemia of the Cns 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12969
NCIt 47 C5440
UMLS 69 C1332884

Summaries for Central Nervous System Leukemia

Disease Ontology : 12 A hematologic cancer located in the central nervous system.

MalaCards based summary : Central Nervous System Leukemia, also known as leukemia of the cns, is related to leukemia and teratocarcinoma. An important gene associated with Central Nervous System Leukemia is AFDN (Afadin, Adherens Junction Formation Factor), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Dendritic Cells Developmental Lineage Pathway. The drugs Cyclophosphamide and Cytarabine have been mentioned in the context of this disorder. Affiliated tissues include brain, myeloid and b cells, and related phenotypes are Synthetic lethal with vaccinia virus (VACV) infection and integument

Related Diseases for Central Nervous System Leukemia

Graphical network of the top 20 diseases related to Central Nervous System Leukemia:



Diseases related to Central Nervous System Leukemia

Symptoms & Phenotypes for Central Nervous System Leukemia

GenomeRNAi Phenotypes related to Central Nervous System Leukemia according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with vaccinia virus (VACV) infection GR00362-A 8.8 AFDN MME RUNX1

MGI Mouse Phenotypes related to Central Nervous System Leukemia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.92 ANPEP CD19 MME RUNX1

Drugs & Therapeutics for Central Nervous System Leukemia

Drugs for Central Nervous System Leukemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 381)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
2
Cytarabine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 147-94-4 6253
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-02-2 5743
4
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
5
Etoposide Approved Phase 4,Phase 3,Phase 2 33419-42-0 36462
6
Methotrexate Approved Phase 4,Phase 2,Phase 3,Phase 1 1959-05-2, 59-05-2 126941
7
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
8
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
9
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1 174722-31-7 10201696
10
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
11
Asparaginase Approved Phase 4,Phase 3,Phase 2,Phase 1 9015-68-3
12
Cladribine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 4291-63-8 20279
13
Daunorubicin Approved Phase 4,Phase 2,Phase 3 20830-81-3 30323
14
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
15
Ketamine Approved, Vet_approved Phase 4,Phase 3 6740-88-1 3821
16
Ifosfamide Approved Phase 4,Phase 3,Phase 2 3778-73-2 3690
17
Vindesine Approved Phase 4,Phase 3,Phase 2 59917-39-4, 53643-48-4 40839
18
Thioguanine Approved Phase 4,Phase 3 154-42-7 2723601
19
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
20
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
21
Nitric Oxide Approved Phase 4 10102-43-9 145068
22
Nitrous oxide Approved, Vet_approved Phase 4 10024-97-2 948
23
Prilocaine Approved Phase 4 721-50-6 4906
24
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 59-30-3 6037
25
leucovorin Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 58-05-9 143 6006
26
Doxil Approved June 1999 Phase 4,Phase 3,Phase 2,Phase 1 31703
27 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
28 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
29 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
30 Antiemetics Phase 4,Phase 2,Phase 3,Phase 1
31 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
32 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
33 Antimetabolites Phase 4,Phase 2,Phase 3,Phase 1
34 Antimetabolites, Antineoplastic Phase 4,Phase 2,Phase 3,Phase 1
35 Antimitotic Agents Phase 4,Phase 3,Phase 2,Phase 1
36 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
37 Antineoplastic Agents, Phytogenic Phase 4,Phase 3,Phase 2,Phase 1
38 Antirheumatic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
39 Antiviral Agents Phase 4,Phase 2,Phase 3,Phase 1
40 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1
41 BB 1101 Phase 4,Phase 2,Phase 3,Phase 1
42 Dermatologic Agents Phase 4,Phase 2,Phase 3,Phase 1
43 Dexamethasone acetate Phase 4,Phase 2,Phase 3,Phase 1 1177-87-3
44 Etoposide phosphate Phase 4,Phase 3,Phase 2
45 Folic Acid Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
46 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
47 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
48 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
49 Hormones Phase 4,Phase 2,Phase 3,Phase 1
50 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 240)

id Name Status NCT ID Phase Drugs
1 Trial for the Treatment of Newly Diagnosed Mature B-Cell Acute Lymphoblastic Leukemia (B-ALL), Burkitt's Non-Hodgkin's Lymphoma (NHL) and Other High-grade Lymphoma in Adults Completed NCT00199082 Phase 4 Adriamycin;Cyclophosphamide;Cytarabine;Dexamethasone/Prednisolone;VP16;Ifosfamide;Methotrexate;G-CSF;Rituximab;Vincristine/Vindesine
2 German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults Completed NCT00199017 Phase 4 Dexamethasone/Prednisolone;Cyclophosphamide;Vincristine;Daunorubicin;Asparaginase;G-CSF;Mercaptopurine;Cytarabine;Methotrexate;VP16;Vindesine;Adriamycin;Thioguanine;HDARAC;Cladribine
3 Learning Impairments Among Survivors of Childhood Cancer Completed NCT00576472 Phase 4 Methylphenidate
4 Evaluation of the Analgesy With Emla and/or Nitrous Oxide in Pediatric Patients for Lumbar Puncture Completed NCT00808171 Phase 4 Livopan;Livopan;EMLA
5 Efficacy of Dexamethasone for Prevent Vomiting in Leukemic Children Who Receive Intrathecal Chemotherapy Completed NCT01094990 Phase 4 Dexamethasone
6 Treatment of Acute Lymphoblastic Leukemia or Aggressive Lymphoma With Relapse in Central Nervous System With Depocyt Unknown status NCT00199108 Phase 2, Phase 3 Depocyt;Dexamethasone
7 Therapy-Optimization Trial for the Treatment of Acute Myeloid Leukemias (AML) in Children and Adolescents Unknown status NCT00111345 Phase 2, Phase 3 Anthracyclines;liposomal daunorubicin;2-CDA;AI
8 Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal Tumors Unknown status NCT00278239 Phase 3
9 Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia Unknown status NCT00445497 Phase 3 amoxicillin-clavulanate potassium;ciprofloxacin
10 Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia Unknown status NCT00020865 Phase 3 cefepime hydrochloride;levofloxacin
11 Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain Unknown status NCT01316744 Phase 3 ketamine hydrochloride
12 Intrathecal DepoCyte and Lineage-targeted Minimal Residual Disease-oriented Therapy of Acute Lymphoblastic Leukemia Completed NCT00795756 Phase 2, Phase 3 liposome-encapsulated cytarabine (DepoCyte);Triple intrathecal therapy (TIT)
13 Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain Completed NCT00293358 Phase 3 carboplatin;cisplatin;etoposide phosphate;ifosfamide
14 Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia Completed NCT00005596 Phase 3 cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;leucovorin calcium;mercaptopurine;methotrexate;pegaspargase;thioguanine;vincristine sulfate
15 Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain Completed NCT00666211 Phase 3
16 Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial Completed NCT00750009 Phase 3
17 Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00005590 Phase 3 levofloxacin
18 Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment Completed NCT00006348 Phase 3 ondansetron
19 Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter Completed NCT00006083 Phase 3 Fragmin
20 St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer Completed NCT00005805 Phase 3
21 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
22 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
23 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
24 Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment Recruiting NCT02881086 Phase 3 Rituximab;Nelarabine;PEG-Asparaginase;Imatinib;Idarubicin;Dexamethasone;Cyclophosphamide;Fludarabine;Vincristine;Mercaptopurine;VP16;Daunorubicin (DNR);Methotrexate;Cytarabine;Vindesine;Adriamycin;Prednisolone
25 Randomized Phase III Study of Decitabine +/- Hydroxyurea (HY) Versus HY in Advanced Proliferative CMML Recruiting NCT02214407 Phase 3 Decitabine;HYDROXYUREA
26 Study to Evaluate the Effect of Aprepitant in Children and Adolescents Receiving AML Remission Induction Chemotherapy Recruiting NCT02979548 Phase 3 Aprepitant;Ondansetron;Metoclopramide
27 Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia Active, not recruiting NCT00549848 Phase 3 Prednisone, Vincristine, Daunorubicin, PEG-L-asparaginase, Erwinia L-asparaginase, Doxorubicin, Cyclophosphamide, Cytarabine, Thioguanine;Clofarabine, Methotrexate, Mercaptopurine, Dexamethasone, Etoposide, Dasatinib
28 Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy Active, not recruiting NCT00683319 Phase 3 carboplatin;cisplatin;cyclophosphamide;methotrexate;vincristine sulfate
29 Liposomal Cytarabine for Central Nervous System (CNS)-Treatment in High-risk Acute Lymphoblastic Leukemia (ALL) Suspended NCT00991744 Phase 3 Liposomal cytarabine;Intrathecal triple
30 Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations Suspended NCT02883049 Phase 3 Clofarabine;Cyclophosphamide;Cytarabine;Dasatinib;Dexamethasone;Doxorubicin Hydrochloride;Etoposide;Hydrocortisone Sodium Succinate;Leucovorin Calcium;Mercaptopurine;Methotrexate;Pegaspargase;Prednisone;Thioguanine;Vincristine Sulfate
31 Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia Terminated NCT00187005 Phase 3 Prednisone, Dexamethasone, Vincristine, Daunorubicin, PEG-L-asparaginase;L-asparaginase, Methotrexate, Idarubicin, Etoposide, Cyclophosphamide, Cytarabine, Mercaptopurine
32 Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia Terminated NCT00002961 Phase 3 cyclophosphamide;cyclosporine;etoposide;methotrexate;Busulfan;Mesna
33 Use of Lipid Emulsion or Nanoemulsion of Propofol on Children Undergoing Ambulatory Invasive Procedures. Withdrawn NCT01326078 Phase 2, Phase 3 propofol
34 Treatment of Philadelphia-Positive Acute Lymphocytic Leukemia (Ph+ ALL) in the Elderly With Imatinib Mesylate (STI571) and Chemotherapy. Unknown status NCT00149136 Phase 2 imatinib
35 Safety and Efficacy of an Adult Acute Lymphoblastic Leukemia Chemotherapy for Adult Lymphoblastic Lymphoma Unknown status NCT00195871 Phase 2 Prednisone, vincristine, daunorubicin , cyclophosphamide , L.-asparaginase, cytosine-arabinoside, methotrexate, etoposide
36 Cisplatin and Temozolomide in Treating Young Patients With Malignant Glioma Unknown status NCT00360945 Phase 2 cisplatin;temozolomide
37 Thiotepa and Radiation Therapy in Treating Young Patients With Newly Diagnosed Malignant Brain Tumors Unknown status NCT00313521 Phase 2 thiotepa
38 Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma Unknown status NCT00514397 Phase 2 motexafin gadolinium;temozolomide
39 Etoposide in Treating Young Patients With Relapsed Ependymoma Unknown status NCT00278252 Phase 2 etoposide
40 Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Metastatic Medulloblastoma Who Have Undergone Surgery Unknown status NCT00276666 Phase 2 cisplatin;lomustine;vincristine sulfate
41 High-Dose Methotrexate in Treating Young Patients With Residual Ependymoma Unknown status NCT00287924 Phase 2 methotrexate
42 Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma Unknown status NCT00024336 Phase 2 tamoxifen citrate
43 Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitive Neuroectodermal Tumors Unknown status NCT00274911 Phase 2 cisplatin;lomustine;vincristine sulfate
44 Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors Unknown status NCT00281905 Phase 2 carboplatin;cisplatin;cyclophosphamide;methotrexate;vincristine sulfate
45 Methotrexate and Temozolomide Versus Methotrexate, Procarbazine, Vincristine and Cytarabine Unknown status NCT00503594 Phase 2 Methotrexate and temozolomide;Methotrexate , procarbazine ,vincristine ,cytarabine
46 Phase Ib Study of SC Milatuzumab in SLE Unknown status NCT01845740 Phase 1, Phase 2 milatuzumab;Placebo
47 Low Dose CdA Combined With Valproic Acid (VPA) in Previously Treated B-cell Chronic Lymphocytic Leukemia(B-CLL) Unknown status NCT01295593 Phase 1, Phase 2 valproic acid and 2-chlorodeoxyadenosine
48 Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma Unknown status NCT00621036 Phase 2 methotrexate;thiotepa
49 Valproic Acid in Treating Patients With Previously Treated Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Chronic Lymphocytic Leukemia Unknown status NCT01016990 Phase 2 valproic acid
50 Phase I/II Trial of ATRA and TCP in Patients With Relapsed or Refractory AML and no Intensive Treatment is Possible Unknown status NCT02261779 Phase 1, Phase 2 Tranylcypromine;Tretinoin

Search NIH Clinical Center for Central Nervous System Leukemia

Genetic Tests for Central Nervous System Leukemia

Anatomical Context for Central Nervous System Leukemia

MalaCards organs/tissues related to Central Nervous System Leukemia:

39
Brain, Myeloid, B Cells, T Cells, Bone, Liver, Bone Marrow

Publications for Central Nervous System Leukemia

Articles related to Central Nervous System Leukemia:

(show top 50) (show all 64)
id Title Authors Year
1
Comprehensive craniospinal radiation for controlling central nervous system leukemia. ( 25539370 )
2014
2
Establishment of NOD/SCID mouse model of central nervous system leukemia. ( 24927394 )
2014
3
Predictive role of cerebrospinal fluid hydrogen sulfide in central nervous system leukemia. ( 22340157 )
2011
4
Does VEGF secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight-junction proteins in central nervous system leukemia? ( 21398042 )
2011
5
Controversies in the management of central nervous system leukemia. ( 20469977 )
2010
6
Central nervous system leukemia on magnetic resonance imaging. ( 18310989 )
2008
7
Prophylaxis of central nervous system leukemia: a case of chronic myeloid leukemia with lymphoid blast crisis treated with imatinib mesylate. ( 18661773 )
2008
8
Primary central nervous system leukemia presenting with an isolated oculomotor palsy. ( 18710807 )
2008
9
Childhood central nervous system leukemia: historical perspectives, current therapy, and acute neurological sequelae. ( 17924103 )
2007
10
Remission of Philadelphia chromosome-positive central nervous system leukemia after dasatinib therapy. ( 17487757 )
2007
11
Detection of central nervous system leukemia in children with acute lymphoblastic leukemia by real-time polymerase chain reaction. ( 15681484 )
2005
12
Risk and prognosis of central nervous system leukemia in patients with Philadelphia chromosome-positive acute leukemias treated with imatinib mesylate. ( 14581336 )
2003
13
Bilateral optic nerve infiltration in central nervous system leukemia. ( 12504706 )
2003
14
Central nervous system leukemia recurring over more than 16 years. ( 10797368 )
2000
15
Primary central nervous system leukemia with a novel chromosomal translocation. ( 9335020 )
1997
16
Central nervous system leukemia. ( 8868094 )
1996
17
Biotherapy for xenografted human central nervous system leukemia in mice with severe combined immunodeficiency using B43 (anti-CD19)-pokeweed antiviral protein immunotoxin. ( 7537120 )
1995
18
Cerebrospinal fluid neopterin levels in children with central nervous system leukemia. ( 8348070 )
1993
19
The role of systemic high-dose cytarabine in the treatment of central nervous system leukemia. Clinical results in 46 patients. ( 8319175 )
1993
20
Temporal bone findings in central nervous system leukemia. ( 1812774 )
1991
21
Tumor necrosis factor in the cerebrospinal fluid of children with central nervous system leukemia. ( 1901928 )
1991
22
Effective prevention of central nervous system leukemia with intrathecal methotrexate and intrathecal methotrexate, cytosine arabinoside, and hydrocortisone in childhood acute lymphocytic leukemia. ( 2323651 )
1990
23
Central nervous system leukemia. ( 3047654 )
1988
24
Identification of risk groups for development of central nervous system leukemia in adults with acute lymphocytic leukemia. ( 3052630 )
1988
25
Significance of cerebrospinal fluid ferritin estimation in central nervous system leukemia. ( 3113843 )
1987
26
Elevation of cerebrospinal fluid sialic acid concentration in children with central nervous system leukemia. ( 3296627 )
1987
27
Intermittent central nervous system irradiation and intrathecal chemotherapy for central nervous system leukemia in children. ( 3624023 )
1987
28
Pickwickian syndrome related to central nervous system leukemia. ( 3458358 )
1986
29
Millipore filter vs cytocentrifuge for detection of childhood central nervous system leukemia. ( 2425776 )
1986
30
Central nervous system leukemia in children with acute nonlymphoblastic leukemia. ( 3840394 )
1985
31
The central nervous system leukemia: a clinical and pathological study. ( 3860195 )
1985
32
A unique pattern of central nervous system leukemia in acute myelomonocytic leukemia associated with inv(16)(p13q22). ( 3857943 )
1985
33
Sequential combination of systemic high-dose ara-C and asparaginase for the treatment of central nervous system leukemia and lymphoma. ( 6366149 )
1984
34
Intrathecal methotrexate versus central nervous system leukemia. ( 6399986 )
1984
35
Recognition of central nervous system leukemia by flow cytometry. ( 6596184 )
1984
36
Reduction in central nervous system leukemia with a pharmacokinetically derived intrathecal methotrexate dosage regimen. ( 6366138 )
1983
37
Diabetes insipidus associated with central nervous system leukemia. ( 7123345 )
1982
38
Aziridinylbenzoquinone (AZQ) treatment of central nervous system leukemia. ( 6958367 )
1982
39
Central nervous system leukemia and lymphoma: computed tomographic manifestations. ( 6976091 )
1981
40
Scanning electron microscopic study on central nervous system leukemia in children. ( 292293 )
1979
41
Intraventricular versus intralumbar methotrexate for central-nervous-system leukemia: prolonged remission with the Ommaya reservoir. ( 288969 )
1979
42
Cerebrospinal fluid polyamine monitoring in central nervous system leukemia. ( 852128 )
1977
43
Central nervous system leukemia. ( 267618 )
1977
44
The value of maintenance therapy following treatment of central nervous system leukemia. ( 332318 )
1977
45
Central nervous system leukemia in childhood. ( 927864 )
1977
46
Antimetaboliths in the prophylaxis and treatment of central nervous system leukemia. ( 267507 )
1977
47
Preventing central nervous system leukemia. ( 990041 )
1976
48
Adult central nervous system leukemia: incidence and clinicopathologic features. ( 822517 )
1976
49
Complications of intrathecal methotrexate prophylaxis and treatment of central nervous system leukemia in children. ( 1071901 )
1976
50
Central nervous system leukemia. ( 1094335 )
1975

Variations for Central Nervous System Leukemia

Expression for Central Nervous System Leukemia

Search GEO for disease gene expression data for Central Nervous System Leukemia.

Pathways for Central Nervous System Leukemia

Pathways related to Central Nervous System Leukemia according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.2 ANPEP CD19 MME
2 11.14 CD19 MME
3 10.88 CD19 MME
4 10.79 ANPEP CD19 MME

GO Terms for Central Nervous System Leukemia

Cellular components related to Central Nervous System Leukemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 secretory granule membrane GO:0030667 8.62 ANPEP MME

Biological processes related to Central Nervous System Leukemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 8.8 ANPEP CDA MME

Molecular functions related to Central Nervous System Leukemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peptide binding GO:0042277 8.62 ANPEP MME

Sources for Central Nervous System Leukemia

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34 ICD10 via Orphanet
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42 MeSH
43 MESH via Orphanet
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60 QIAGEN
65 SNOMED-CT via HPO
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