MCID: CNT044
MIFTS: 23

Central Nervous System Primitive Neuroectodermal Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Central Nervous System Primitive Neuroectodermal Neoplasm

MalaCards integrated aliases for Central Nervous System Primitive Neuroectodermal Neoplasm:

Name: Central Nervous System Primitive Neuroectodermal Neoplasm 12 14
Cpnet 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0060103
UMLS 69 C3887678

Summaries for Central Nervous System Primitive Neuroectodermal Neoplasm

MalaCards based summary : Central Nervous System Primitive Neuroectodermal Neoplasm, also known as cpnet, is related to adult central nervous system primitive neuroectodermal neoplasm and childhood central nervous system primitive neuroectodermal neoplasm. An important gene associated with Central Nervous System Primitive Neuroectodermal Neoplasm is LIN28A (Lin-28 Homolog A), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Related phenotypes are behavior/neurological and normal

Related Diseases for Central Nervous System Primitive Neuroectodermal Neoplasm

Diseases in the Central Nervous System Primitive Neuroectodermal Neoplasm family:

Adult Central Nervous System Primitive Neuroectodermal Neoplasm

Diseases related to Central Nervous System Primitive Neuroectodermal Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 187)
# Related Disease Score Top Affiliating Genes
1 adult central nervous system primitive neuroectodermal neoplasm 12.4
2 childhood central nervous system primitive neuroectodermal neoplasm 12.4
3 malignant sertoli cell tumor 10.3 ENO2 SYP
4 urinary bladder small cell neuroendocrine carcinoma 10.3 ENO2 SYP
5 atypical choroid plexus papilloma 10.3 DICER1 SYP
6 sinonasal undifferentiated carcinoma 10.3 ENO2 SYP
7 auditory system cancer 10.3 ENO2 SYP
8 cutaneous ganglioneuroma 10.3 ENO2 SYP
9 sensory organ benign neoplasm 10.3 ENO2 SYP
10 middle ear adenoma 10.3 ENO2 SYP
11 gallbladder small cell carcinoma 10.3 ENO2 SYP
12 pancreatic somatostatinoma 10.3 ENO2 SYP
13 extrahepatic bile duct adenocarcinoma 10.3 ENO2 SYP
14 small cell carcinoma of the bladder 10.3 ENO2 SYP
15 papillary tumor of the pineal region 10.3 ENO2 SYP
16 orbital cancer 10.3 ENO2 SYP
17 ovarian carcinosarcoma 10.3 ENO2 SYP
18 pulmonary large cell neuroendocrine carcinoma 10.3 ENO2 SYP
19 olfactory nerve neoplasm 10.3 ENO2 SYP
20 cauda equina neoplasm 10.3 ENO2 SYP
21 extraosseous chondrosarcoma 10.3 ENO2 SYP
22 malignant teratoma 10.3 ENO2 SYP
23 endometrial small cell carcinoma 10.3 ENO2 SYP
24 mucinous ovarian cystadenoma 10.3 ENO2 SYP
25 angiomyoma 10.3 ENO2 SYP
26 gastric squamous cell carcinoma 10.3 ENO2 SYP
27 gastric small cell carcinoma 10.3 ENO2 SYP
28 desmoplastic infantile ganglioglioma 10.3 GFAP SYP
29 extraventricular neurocytoma 10.3 GFAP SYP
30 bone benign neoplasm 10.3 ENO2 SYP
31 lung combined type small cell carcinoma 10.3 GFAP SYP
32 carcinoid tumors, intestinal 10.3 ENO2 SYP
33 cervical clear cell adenocarcinoma 10.3 ENO2 SYP
34 extraskeletal ewing sarcoma 10.3 ENO2 SYP
35 cranial nerve malignant neoplasm 10.3 ENO2 SYP
36 gangliocytoma 10.3 GFAP SYP
37 rhabdoid meningioma 10.3 GFAP SYP
38 connective tissue benign neoplasm 10.3 ENO2 SYP
39 pilomyxoid astrocytoma 10.3 GFAP SYP
40 intraocular retinoblastoma 10.3 ENO2 SYP
41 chordoid meningioma 10.3 GFAP SYP
42 sclerosing hemangioma 10.3 ENO2 SYP
43 chiari malformation 10.3 GFAP SYP
44 carcinoid syndrome 10.3 ENO2 SYP
45 anaplastic ependymoma 10.3 GFAP SYP
46 intracranial cysts 10.3 ENO2 GFAP
47 angiocentric glioma 10.2 GFAP SYP
48 obstructive hydrocephalus 10.2 GFAP SYP
49 pineal parenchymal tumor of intermediate differentiation 10.2 ENO2 SYP
50 primitive neuroectodermal tumor of the cervix uteri 10.2 ENO2 GFAP

Graphical network of the top 20 diseases related to Central Nervous System Primitive Neuroectodermal Neoplasm:



Diseases related to Central Nervous System Primitive Neuroectodermal Neoplasm

Symptoms & Phenotypes for Central Nervous System Primitive Neuroectodermal Neoplasm

MGI Mouse Phenotypes related to Central Nervous System Primitive Neuroectodermal Neoplasm:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.43 SYP TP53 DICER1 ENO2 GFAP LIN28A
2 normal MP:0002873 9.02 LIN28A SYP TP53 DICER1 GFAP

Drugs & Therapeutics for Central Nervous System Primitive Neuroectodermal Neoplasm

Search Clinical Trials , NIH Clinical Center for Central Nervous System Primitive Neuroectodermal Neoplasm

Genetic Tests for Central Nervous System Primitive Neuroectodermal Neoplasm

Anatomical Context for Central Nervous System Primitive Neuroectodermal Neoplasm

Publications for Central Nervous System Primitive Neuroectodermal Neoplasm

Articles related to Central Nervous System Primitive Neuroectodermal Neoplasm:

# Title Authors Year
1
Central primary primitive neuroectodermal tumor (cPNET) arising from an ovarian mature cystic teratoma in pregnancy: A case report and review of medical literature. ( 24371678 )
2013

Variations for Central Nervous System Primitive Neuroectodermal Neoplasm

Expression for Central Nervous System Primitive Neuroectodermal Neoplasm

Search GEO for disease gene expression data for Central Nervous System Primitive Neuroectodermal Neoplasm.

Pathways for Central Nervous System Primitive Neuroectodermal Neoplasm

Pathways related to Central Nervous System Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.66 ENO2 GFAP SYP
2 10.7 GFAP NES SYP

GO Terms for Central Nervous System Primitive Neuroectodermal Neoplasm

Cellular components related to Central Nervous System Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 8.62 GFAP NES

Biological processes related to Central Nervous System Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 gene silencing by RNA GO:0031047 9.16 DICER1 LIN28A
2 miRNA metabolic process GO:0010586 8.96 DICER1 LIN28A
3 pre-miRNA processing GO:0031054 8.62 DICER1 LIN28A

Molecular functions related to Central Nervous System Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein self-association GO:0043621 8.62 SYP TP53

Sources for Central Nervous System Primitive Neuroectodermal Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
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47 NDF-RT
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53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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