MCID: CNT007
MIFTS: 30

Central Nervous System Tuberculosis malady

Neuronal diseases, Infectious diseases categories

Summaries for Central Nervous System Tuberculosis

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Sources:
9Disease Ontology, 34MalaCards
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Disease Ontology:9 An extrapulmonary tuberculosis that results in formation of tuberculomas located in brain or located in spinal cord.

MalaCards: Central Nervous System Tuberculosis, also known as intracranial tuberculoma, is related to tuberculosis and meningitis. An important gene associated with Central Nervous System Tuberculosis is MMP9 (matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)). Affiliated tissues include brain or, brain and spinal cord.

Aliases & Classifications for Central Nervous System Tuberculosis

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Sources:
9Disease Ontology, 63UMLS, 59SNOMED-CT, 28ICD9CM, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

central nervous system tuberculosis 9
intracranial tuberculoma 9 63
tuberculosis of meninges and central nervous system 9
tuberculosis, central nervous system 63
tuberculous abscess of brain 9
tuberculoma of brain 9


External Ids:

Disease Ontology9 DOID:1638
ICD9CM28 013.20, 013.2
SNOMED-CT59 416265003, 40769007
MeSH36 D016862

Related Diseases for Central Nervous System Tuberculosis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Central Nervous System Tuberculosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1tuberculosis11.1
2meningitis10.4
3tuberculous meningitis10.4
4acquired immunodeficiency syndrome10.3
5miliary tuberculosis10.2
6systemic lupus erythematosus10.2
7arthritis10.2
8dementia10.2
9hypopituitarism10.2
10lupus erythematosus10.2
11retinal vein occlusion10.2
12retinitis10.2
13crohn's disease10.1
14choroiditis10.1
15cerebritis10.1
16anterior cerebral artery infarction10.1
17abdominal tuberculosis10.1
18foot drop10.1

Graphical network of diseases related to Central Nervous System Tuberculosis:



Diseases related to central nervous system tuberculosis

Symptoms for Central Nervous System Tuberculosis

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Drugs & Therapeutics for Central Nervous System Tuberculosis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Central Nervous System Tuberculosis

Drug clinical trials:

Search ClinicalTrials for Central Nervous System Tuberculosis

Search NIH Clinical Center for Central Nervous System Tuberculosis

Search CenterWatch for Central Nervous System Tuberculosis

Genetic Tests for Central Nervous System Tuberculosis

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Anatomical Context for Central Nervous System Tuberculosis

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Sources:
34MalaCards, 15FMA
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MalaCards organs/tissues related to Central Nervous System Tuberculosis:

34
Brain, Spinal cord, Lymph node, Monocytes, T cells

FMA organs/tissues related to Central Nervous System Tuberculosis:

15
Brain or

Animal Models for Central Nervous System Tuberculosis or affiliated genes

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Publications for Central Nervous System Tuberculosis

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Sources:
53PubMed
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Articles related to Central Nervous System Tuberculosis:

(show top 50)    (show all 62)
idTitleAuthorsYear
1
Central nervous system tuberculosis presenting as branch retinal vein occlusion. (22738141)
2013
2
The dual face of central nervous system tuberculosis: a new Janus Bifrons? (23305698)
2013
3
Central Nervous System Tuberculosis: Challenges and Advances in Diagnosis and Treatment. (24122343)
2013
4
Central nervous system tuberculosis: a disease from Papua New Guinea in North Queensland. (23480051)
2013
5
A life-threatening central nervous system-tuberculosis inflammatory reaction nonresponsive to corticosteroids and successfully controlled by infliximab in a young patient with a variant of juvenile idiopathic arthritis. (22647865)
2012
6
Central nervous system tuberculosis: a forgotten diagnosis. (22735252)
2012
7
The PCR-Based Diagnosis of Central Nervous System Tuberculosis: Up to Date. (22666577)
2012
8
Multi-drug-resistant central nervous system tuberculosis. (22626692)
2012
9
Central nervous system tuberculosis: mimicking neuropsychiatric systemic lupus erythematosus. (22367698)
2012
10
Role of Mycobacterium tuberculosis pknD in the pathogenesis of central nervous system tuberculosis. (22243650)
2012
11
Central nervous system tuberculosis: pathophysiology and imaging findings. (23122262)
2012
12
Central nervous system tuberculosis in non-HIV-positive children: a single-center, 6 year experience. (22095412)
2012
13
Central nervous system tuberculosis. (22032500)
2011
14
Hypopituitarism as unusual sequelae to central nervous system tuberculosis. (22029037)
2011
15
Treatment of central nervous system tuberculosis infections and neurological complications of tuberculosis treatment. (21834764)
2011
16
Ophthalmic manifestations of central nervous system tuberculosis--two case reports. (22533169)
2011
17
Central nervous system tuberculosis. (21572867)
2011
18
Central nervous system tuberculosis masquerading as primary dementia: a case report. (22127948)
2011
19
Management of central nervous system tuberculosis in children: light and shade. (21222370)
2010
20
Central nervous system tuberculosis and adjuvant corticosteroid therapy. (19182749)
2009
21
Pathogenesis of central nervous system tuberculosis. (19275620)
2009
22
Diagnostic challenges of central nervous system tuberculosis. (18760024)
2008
23
Unusual central nervous system tuberculosis debut in children: stroke. (18259759)
2008
24
Improved diagnosis of central nervous system tuberculosis by MPB64-Target PCR. (24031203)
2008
25
Central nervous system tuberculosis: pathogenesis and clinical aspects. (18400795)
2008
26
Diagnosis of central nervous system tuberculosis by T-cell-based assays on peripheral blood and cerebrospinal fluid mononuclear cells. (18632925)
2008
27
Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo. (17202385)
2007
28
IFNgamma synergizes with IL-1beta to up-regulate MMP-9 secretion in a cellular model of central nervous system tuberculosis. (17158965)
2007
29
Mortality associated with central nervous system tuberculosis. (17920686)
2007
30
Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis. (16586367)
2006
31
Central nervous system tuberculosis and paradoxical response. (16634237)
2006
32
New face of the old foe: central nervous system tuberculosis. (16295809)
2005
33
Diagnostic value of cytokine measurement in cerebrospinal fluid in children with central nervous system tuberculosis. (11388321)
2001
34
Central nervous system tuberculosis: imaging manifestations. (10775956)
2000
35
Paradoxical enlargement of lymph nodes during therapy of central nervous system tuberculosis. (17277474)
1999
36
Central nervous system tuberculosis. (10517926)
1999
37
Central nervous system tuberculosis after resolution of miliary tuberculosis. (9655548)
1998
38
Central nervous system tuberculosis--the paradox of the host immune response. (9515661)
1998
39
Neuroimaging of central nervous system tuberculosis in HIV-infected patients. (9113686)
1997
40
Paradoxical progression of tuberculous lesions during chemotherapy of central nervous system tuberculosis. Report of four cases. (7616286)
1995
41
MR imaging of central nervous system tuberculosis. (7610244)
1995
42
Central nervous system tuberculosis in HIV-infected patients: clinical and radiographic findings. (7677034)
1995
43
Central nervous system tuberculosis: medical management and surgical indications. (8553259)
1995
44
Central nervous system tuberculosis: MRI. (8183466)
1994
45
Central nervous system tuberculosis in infants and children. (8299041)
1993
46
Central nervous system tuberculosis in children. (1930419)
1991
47
Central nervous system tuberculosis in children: a review of 30 cases. (2235168)
1990
48
Central nervous system tuberculosis with the acquired immunodeficiency syndrome and its related complex. (3729203)
1986
49
Central nervous system tuberculosis related to pregnancy. (7172697)
1982
50
Central nervous system tuberculosis: a persistent disease. (5312859)
1971

Variations for Central Nervous System Tuberculosis

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Expression for genes affiliated with Central Nervous System Tuberculosis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Central Nervous System Tuberculosis

Search GEO for disease gene expression data for Central Nervous System Tuberculosis.

Pathways for genes affiliated with Central Nervous System Tuberculosis

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Compounds for genes affiliated with Central Nervous System Tuberculosis

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GO Terms for genes affiliated with Central Nervous System Tuberculosis

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Products for genes affiliated with Central Nervous System Tuberculosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Central Nervous System Tuberculosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet