MCID: CNT007
MIFTS: 28

Central Nervous System Tuberculosis malady

Neuronal diseases category

Summaries for Central Nervous System Tuberculosis

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Sources:
8Disease Ontology, 32MalaCards
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Disease Ontology:8 An extrapulmonary tuberculosis that results in formation of tuberculomas located in brain or located in spinal cord.

MalaCards: Central Nervous System Tuberculosis, also known as intracranial tuberculoma, is related to tuberculosis and meningitis. An important gene associated with Central Nervous System Tuberculosis is MMP9 (matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)). Affiliated tissues include brain or, brain and spinal cord.

Aliases & Classifications for Central Nervous System Tuberculosis

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Sources:
8Disease Ontology, 60UMLS, 27ICD9CM, 34MeSH, 56SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

central nervous system tuberculosis 8
intracranial tuberculoma 8 60
tuberculosis of meninges and central nervous system 8
tuberculosis, central nervous system 60
tuberculous abscess of brain 8
tuberculoma of brain 8


External Ids:

Disease Ontology8 DOID:1638
ICD9CM27 013.20, 013.2
SNOMED-CT56 40769007, 416265003
MeSH34 D016862

Related Diseases for Central Nervous System Tuberculosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Central Nervous System Tuberculosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1tuberculosis11.1
2meningitis10.4
3acquired immunodeficiency syndrome10.3
4central nervous system disease10.3
5nervous system disease10.3
6systemic lupus erythematosus10.2
7miliary tuberculosis10.2
8lymph node tuberculosis10.2
9arthritis10.2
10dementia10.2
11hypopituitarism10.2
12lupus erythematosus10.2
13retinitis10.2
14crohn's disease10.1
15choroiditis10.1
16anterior cerebral artery infarction10.1
17abdominal tuberculosis10.1

Graphical network of diseases related to Central Nervous System Tuberculosis:



Diseases related to central nervous system tuberculosis

Clinical Features for Central Nervous System Tuberculosis

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Drugs & Therapeutics for Central Nervous System Tuberculosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Central Nervous System Tuberculosis

Drug clinical trials:

Search ClinicalTrials for Central Nervous System Tuberculosis

Search NIH Clinical Center for Central Nervous System Tuberculosis

Search CenterWatch for Central Nervous System Tuberculosis

Genetic Tests for Central Nervous System Tuberculosis

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Anatomical Context for Central Nervous System Tuberculosis

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Central Nervous System Tuberculosis:

32
Brain, Spinal cord, Lymph node, Monocytes, T cells

FMA organs/tissues related to Central Nervous System Tuberculosis:

14
Brain or

Animal Models for Central Nervous System Tuberculosis or affiliated genes

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Publications for Central Nervous System Tuberculosis

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Sources:
50PubMed
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Articles related to Central Nervous System Tuberculosis:

(show top 50)    (show all 70)
idTitleAuthorsYear
1
Central nervous system tuberculosis presenting as branch retinal vein occlusion. (22738141)
2013
2
The dual face of central nervous system tuberculosis: a new Janus Bifrons? (23305698)
2013
3
Central Nervous System Tuberculosis: Challenges and Advances in Diagnosis and Treatment. (24122343)
2013
4
Tuberculosis of the central nervous system. (24326723)
2013
5
Central nervous system tuberculosis: a disease from Papua New Guinea in North Queensland. (23480051)
2013
6
A life-threatening central nervous system-tuberculosis inflammatory reaction nonresponsive to corticosteroids and successfully controlled by infliximab in a young patient with a variant of juvenile idiopathic arthritis. (22647865)
2012
7
Multi-drug-resistant central nervous system tuberculosis. (22626692)
2012
8
Central nervous system tuberculosis: mimicking neuropsychiatric systemic lupus erythematosus. (22367698)
2012
9
Role of Mycobacterium tuberculosis pknD in the pathogenesis of central nervous system tuberculosis. (22243650)
2012
10
Central nervous system tuberculosis: pathophysiology and imaging findings. (23122262)
2012
11
Central nervous system tuberculosis in non-HIV-positive children: a single-center, 6 year experience. (22095412)
2012
12
Central nervous system tuberculosis. (22032500)
2011
13
Hypopituitarism as unusual sequelae to central nervous system tuberculosis. (22029037)
2011
14
Ophthalmic manifestations of central nervous system tuberculosis--two case reports. (22533169)
2011
15
Central nervous system tuberculosis. (21572867)
2011
16
Ventriculitis caused by Aspergillus fumigatus in a child with central nervous system tuberculosis. (20701684)
2011
17
Management of central nervous system tuberculosis in children: light and shade. (21222370)
2010
18
Central nervous system tuberculosis and adjuvant corticosteroid therapy. (19182749)
2009
19
Central nervous system tuberculosis subsequent to dural grafting. (18973080)
2008
20
Unusual central nervous system tuberculosis debut in children: stroke. (18259759)
2008
21
Improved diagnosis of central nervous system tuberculosis by MPB64-Target PCR. (24031203)
2008
22
Central nervous system tuberculosis: pathogenesis and clinical aspects. (18400795)
2008
23
Magnetic resonance imaging of miliary tuberculosis of the central nervous system in children with tuberculous meningitis. (18931835)
2008
24
Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo. (17202385)
2007
25
BCG vaccination confers poor protection against M. tuberculosis HN878-induced central nervous system disease. (17241704)
2007
26
Mortality associated with central nervous system tuberculosis. (17920686)
2007
27
Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis. (16586367)
2006
28
Miliary tuberculosis involving the central nervous system. (16217692)
2005
29
Modern imaging of tuberculosis in children: thoracic, central nervous system and abdominal tuberculosis. (15372216)
2004
30
Diagnostic value of cytokine measurement in cerebrospinal fluid in children with central nervous system tuberculosis. (11388321)
2001
31
Magnetic resonance imaging in diagnosis of childhood central nervous system tuberculosis. (11440385)
2001
32
Paradoxical enlargement of lymph nodes during therapy of central nervous system tuberculosis. (17277474)
1999
33
Central nervous system tuberculosis. (10517926)
1999
34
Central nervous system tuberculosis after resolution of miliary tuberculosis. (9655548)
1998
35
Central nervous system tuberculosis--the paradox of the host immune response. (9515661)
1998
36
Central nervous system tuberculosis in children: a review of 214 cases. (9794979)
1998
37
Neuroimaging of central nervous system tuberculosis in HIV-infected patients. (9113686)
1997
38
Presumed ocular and central nervous system tuberculosis in a patient with the acquired immunodeficiency syndrome. (8623897)
1996
39
Images in clinical medicine. Miliary tuberculosis involving the central nervous system. (8592551)
1996
40
MR imaging of central nervous system tuberculosis. (7610244)
1995
41
Central nervous system tuberculosis: medical management and surgical indications. (8553259)
1995
42
MR imaging and CT of central nervous system tuberculosis in the patient with AIDS. (7610246)
1995
43
Central nervous system tuberculosis: MRI. (8183466)
1994
44
Central nervous system tuberculosis in infants and children. (8299041)
1993
45
Central nervous system tuberculosis in Australia: a report of 22 cases. (8479355)
1993
46
Central nervous system tuberculosis. (1622527)
1992
47
Central nervous system tuberculosis in children. (1930419)
1991
48
Central nervous system tuberculosis in children: a review of 30 cases. (2235168)
1990
49
Central nervous system tuberculosis with the acquired immunodeficiency syndrome and its related complex. (3729203)
1986
50
Central nervous system tuberculosis related to pregnancy. (7172697)
1982

Genetic Variations for Central Nervous System Tuberculosis

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Expression for genes affiliated with Central Nervous System Tuberculosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Central Nervous System Tuberculosis

Search GEO for disease gene expression data for Central Nervous System Tuberculosis.

Pathways for genes affiliated with Central Nervous System Tuberculosis

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Compounds for genes affiliated with Central Nervous System Tuberculosis

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GO Terms for genes affiliated with Central Nervous System Tuberculosis

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Products for genes affiliated with Central Nervous System Tuberculosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Central Nervous System Tuberculosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet