MCID: CNT007
MIFTS: 26

Central Nervous System Tuberculosis malady

Neuronal category

Summaries for Central Nervous System Tuberculosis

Sources:
8Disease Ontology, 33MalaCards
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Disease Ontology:8 An extrapulmonary tuberculosis that results in formation of tuberculomas located in brain or located in spinal cord.

MalaCards: Central Nervous System Tuberculosis, also known as intracranial tuberculoma, is related to tuberculosis and tuberculous meningitis. An important gene associated with Central Nervous System Tuberculosis is MMP9 (matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)). Affiliated tissues include brain or, lymph node and brain.

Aliases & Classifications for Central Nervous System Tuberculosis

Sources:
8Disease Ontology, 61UMLS, 27ICD9CM, 35MeSH, 57SNOMED-CT
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

central nervous system tuberculosis 8
intracranial tuberculoma 8 61
tuberculosis of meninges and central nervous system 8
tuberculosis, central nervous system 61
tuberculous abscess of brain 8
tuberculoma of brain 8


External Ids:

Disease Ontology8 DOID:1638
ICD9CM27 013.20, 013.2
SNOMED-CT57 40769007, 416265003
MeSH35 D016862

Related Diseases for Central Nervous System Tuberculosis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Central Nervous System Tuberculosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1tuberculosis11.1
2tuberculous meningitis10.4
3acquired immunodeficiency syndrome10.4
4n syndrome10.4
5systemic lupus erythematosus10.2
6miliary tuberculosis10.2
7lymph node tuberculosis10.2
8arthritis10.2
9anterior cerebral artery infarction10.1
10abdominal tuberculosis10.1
11foot drop10.1

Graphical network of diseases related to Central Nervous System Tuberculosis:



Diseases related to central nervous system tuberculosis

Clinical Features for Central Nervous System Tuberculosis

Drugs & Therapeutics for Central Nervous System Tuberculosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Central Nervous System Tuberculosis

Drug clinical trials:

Search ClinicalTrials for Central Nervous System Tuberculosis

Search NIH Clinical Center for Central Nervous System Tuberculosis

Search CenterWatch for Central Nervous System Tuberculosis

Genetic Tests for Central Nervous System Tuberculosis

Anatomical Context for Central Nervous System Tuberculosis

Sources:
14FMA, 33MalaCards
See all sources

MalaCards organs/tissues related to Central Nervous System Tuberculosis:

33
Lymph node, Brain, Spinal cord, Monocytes, T cells

FMA organs/tissues related to Central Nervous System Tuberculosis:

14
Brain or

Animal Models for Central Nervous System Tuberculosis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Central Nervous System Tuberculosis

Sources:
51PubMed
See all sources

Articles related to Central Nervous System Tuberculosis:

(show top 50)    (show all 70)
idTitleAuthorsYear
1
The dual face of central nervous system tuberculosis: a new Janus Bifrons? (23305698)
2013
2
Tuberculosis of the central nervous system. (24326723)
2013
3
Central nervous system tuberculosis: a disease from Papua New Guinea in North Queensland. (23480051)
2013
4
A life-threatening central nervous system-tuberculosis inflammatory reaction nonresponsive to corticosteroids and successfully controlled by infliximab in a young patient with a variant of juvenile idiopathic arthritis. (22647865)
2012
5
Central nervous system tuberculosis: a forgotten diagnosis. (22735252)
2012
6
The PCR-Based Diagnosis of Central Nervous System Tuberculosis: Up to Date. (22666577)
2012
7
Central nervous system tuberculosis: mimicking neuropsychiatric systemic lupus erythematosus. (22367698)
2012
8
Role of Mycobacterium tuberculosis pknD in the pathogenesis of central nervous system tuberculosis. (22243650)
2012
9
Central nervous system tuberculosis: pathophysiology and imaging findings. (23122262)
2012
10
Central nervous system tuberculosis in non-HIV-positive children: a single-center, 6 year experience. (22095412)
2012
11
Hypopituitarism as unusual sequelae to central nervous system tuberculosis. (22029037)
2011
12
Ophthalmic manifestations of central nervous system tuberculosis--two case reports. (22533169)
2011
13
Central nervous system tuberculosis. (21572867)
2011
14
Central nervous system tuberculosis masquerading as primary dementia: a case report. (22127948)
2011
15
Ventriculitis caused by Aspergillus fumigatus in a child with central nervous system tuberculosis. (20701684)
2011
16
The many faces of central nervous system tuberculosis. (21825249)
2011
17
Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control study. (22111973)
2011
18
Management of central nervous system tuberculosis in children: light and shade. (21222370)
2010
19
Pathogenesis of central nervous system tuberculosis. (19275620)
2009
20
Magnetic resonance imaging in central nervous system tuberculosis. (19881100)
2009
21
Central nervous system tuberculosis subsequent to dural grafting. (18973080)
2008
22
Diagnostic challenges of central nervous system tuberculosis. (18760024)
2008
23
Improved diagnosis of central nervous system tuberculosis by MPB64-Target PCR. (24031203)
2008
24
Central nervous system tuberculosis: pathogenesis and clinical aspects. (18400795)
2008
25
Magnetic resonance imaging of miliary tuberculosis of the central nervous system in children with tuberculous meningitis. (18931835)
2008
26
Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo. (17202385)
2007
27
BCG vaccination confers poor protection against M. tuberculosis HN878-induced central nervous system disease. (17241704)
2007
28
IFNgamma synergizes with IL-1beta to up-regulate MMP-9 secretion in a cellular model of central nervous system tuberculosis. (17158965)
2007
29
Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis. (16586367)
2006
30
Central nervous system tuberculosis and paradoxical response. (16634237)
2006
31
Miliary tuberculosis involving the central nervous system. (16217692)
2005
32
Modern imaging of tuberculosis in children: thoracic, central nervous system and abdominal tuberculosis. (15372216)
2004
33
Magnetic resonance imaging in diagnosis of childhood central nervous system tuberculosis. (11440385)
2001
34
Central nervous system tuberculosis. (10517926)
1999
35
Central nervous system tuberculosis after resolution of miliary tuberculosis. (9655548)
1998
36
Central nervous system tuberculosis--the paradox of the host immune response. (9515661)
1998
37
Auditory disorder in central nervous system miliary tuberculosis: case report. (9733241)
1998
38
Neuroimaging of central nervous system tuberculosis in HIV-infected patients. (9113686)
1997
39
Paradoxical progression of tuberculous lesions during chemotherapy of central nervous system tuberculosis. Report of four cases. (7616286)
1995
40
MR imaging of central nervous system tuberculosis. (7610244)
1995
41
Central nervous system tuberculosis in HIV-infected patients: clinical and radiographic findings. (7677034)
1995
42
Central nervous system tuberculosis: medical management and surgical indications. (8553259)
1995
43
MR imaging and CT of central nervous system tuberculosis in the patient with AIDS. (7610246)
1995
44
Central nervous system tuberculosis in infants and children. (8299041)
1993
45
Central nervous system tuberculosis in Australia: a report of 22 cases. (8479355)
1993
46
Central nervous system tuberculosis. (1622527)
1992
47
Central nervous system tuberculosis in children. (1930419)
1991
48
Central nervous system tuberculosis with the acquired immunodeficiency syndrome and its related complex. (3729203)
1986
49
Central nervous system tuberculosis related to pregnancy. (7172697)
1982
50
Central nervous system tuberculosis: a persistent disease. (5312859)
1971

Genetic Variations for Central Nervous System Tuberculosis

Expression for genes affiliated with Central Nervous System Tuberculosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Central Nervous System Tuberculosis

Search GEO for disease gene expression data for Central Nervous System Tuberculosis.

Pathways for genes affiliated with Central Nervous System Tuberculosis

Compounds for genes affiliated with Central Nervous System Tuberculosis

GO Terms for genes affiliated with Central Nervous System Tuberculosis

Products for genes affiliated with Central Nervous System Tuberculosis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Central Nervous System Tuberculosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet