MCID: CNT007
MIFTS: 28

Central Nervous System Tuberculosis malady

Neuronal diseases category

Summaries for Central Nervous System Tuberculosis

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Sources:
8Disease Ontology, 32MalaCards
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Disease Ontology:8 An extrapulmonary tuberculosis that results in formation of tuberculomas located in brain or located in spinal cord.

MalaCards: Central Nervous System Tuberculosis, also known as intracranial tuberculoma, is related to tuberculosis and meningitis. An important gene associated with Central Nervous System Tuberculosis is MMP9 (matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)). Affiliated tissues include brain or, brain and spinal cord.

Aliases & Classifications for Central Nervous System Tuberculosis

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Sources:
8Disease Ontology, 60UMLS, 27ICD9CM, 34MeSH, 56SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

central nervous system tuberculosis 8
intracranial tuberculoma 8 60
tuberculosis of meninges and central nervous system 8
tuberculosis, central nervous system 60
tuberculous abscess of brain 8
tuberculoma of brain 8


External Ids:

Disease Ontology8 DOID:1638
ICD9CM27 013.20, 013.2
SNOMED-CT56 40769007, 416265003
MeSH34 D016862

Related Diseases for Central Nervous System Tuberculosis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Central Nervous System Tuberculosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1tuberculosis11.1
2meningitis10.4
3acquired immunodeficiency syndrome10.3
4central nervous system disease10.3
5nervous system disease10.3
6systemic lupus erythematosus10.2
7miliary tuberculosis10.2
8lymph node tuberculosis10.2
9arthritis10.2
10dementia10.2
11hypopituitarism10.2
12lupus erythematosus10.2
13retinitis10.2
14crohn's disease10.1
15choroiditis10.1
16anterior cerebral artery infarction10.1
17abdominal tuberculosis10.1

Graphical network of diseases related to Central Nervous System Tuberculosis:



Diseases related to central nervous system tuberculosis

Clinical Features for Central Nervous System Tuberculosis

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Drugs & Therapeutics for Central Nervous System Tuberculosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Central Nervous System Tuberculosis

Drug clinical trials:

Search ClinicalTrials for Central Nervous System Tuberculosis

Search NIH Clinical Center for Central Nervous System Tuberculosis

Search CenterWatch for Central Nervous System Tuberculosis

Genetic Tests for Central Nervous System Tuberculosis

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Anatomical Context for Central Nervous System Tuberculosis

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Central Nervous System Tuberculosis:

32
Brain, Spinal cord, Lymph node, Monocytes, T cells

FMA organs/tissues related to Central Nervous System Tuberculosis:

14
Brain or

Animal Models for Central Nervous System Tuberculosis or affiliated genes

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Publications for Central Nervous System Tuberculosis

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Sources:
50PubMed
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Articles related to Central Nervous System Tuberculosis:

(show top 50)    (show all 70)
idTitleAuthorsYear
1
Central nervous system tuberculosis presenting as branch retinal vein occlusion. (22738141)
2013
2
The dual face of central nervous system tuberculosis: a new Janus Bifrons? (23305698)
2013
3
Central Nervous System Tuberculosis: Challenges and Advances in Diagnosis and Treatment. (24122343)
2013
4
A life-threatening central nervous system-tuberculosis inflammatory reaction nonresponsive to corticosteroids and successfully controlled by infliximab in a young patient with a variant of juvenile idiopathic arthritis. (22647865)
2012
5
Central nervous system tuberculosis: a forgotten diagnosis. (22735252)
2012
6
The PCR-Based Diagnosis of Central Nervous System Tuberculosis: Up to Date. (22666577)
2012
7
Role of Mycobacterium tuberculosis pknD in the pathogenesis of central nervous system tuberculosis. (22243650)
2012
8
Central nervous system tuberculosis: pathophysiology and imaging findings. (23122262)
2012
9
Central nervous system tuberculosis in non-HIV-positive children: a single-center, 6 year experience. (22095412)
2012
10
Central nervous system tuberculosis. (22032500)
2011
11
Treatment of central nervous system tuberculosis infections and neurological complications of tuberculosis treatment. (21834764)
2011
12
Central nervous system tuberculosis masquerading as primary dementia: a case report. (22127948)
2011
13
Ventriculitis caused by Aspergillus fumigatus in a child with central nervous system tuberculosis. (20701684)
2011
14
The many faces of central nervous system tuberculosis. (21825249)
2011
15
Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control study. (22111973)
2011
16
Management of central nervous system tuberculosis in children: light and shade. (21222370)
2010
17
Central nervous system tuberculosis. (20944756)
2010
18
Pathogenesis of central nervous system tuberculosis. (19275620)
2009
19
Magnetic resonance imaging in central nervous system tuberculosis. (19881100)
2009
20
Central nervous system tuberculosis subsequent to dural grafting. (18973080)
2008
21
Diagnostic challenges of central nervous system tuberculosis. (18760024)
2008
22
Unusual central nervous system tuberculosis debut in children: stroke. (18259759)
2008
23
Improved diagnosis of central nervous system tuberculosis by MPB64-Target PCR. (24031203)
2008
24
Central nervous system tuberculosis: pathogenesis and clinical aspects. (18400795)
2008
25
Diagnosis of central nervous system tuberculosis by T-cell-based assays on peripheral blood and cerebrospinal fluid mononuclear cells. (18632925)
2008
26
Magnetic resonance imaging of miliary tuberculosis of the central nervous system in children with tuberculous meningitis. (18931835)
2008
27
BCG vaccination confers poor protection against M. tuberculosis HN878-induced central nervous system disease. (17241704)
2007
28
IFNgamma synergizes with IL-1beta to up-regulate MMP-9 secretion in a cellular model of central nervous system tuberculosis. (17158965)
2007
29
Mortality associated with central nervous system tuberculosis. (17920686)
2007
30
Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis. (16586367)
2006
31
Central nervous system tuberculosis and paradoxical response. (16634237)
2006
32
New face of the old foe: central nervous system tuberculosis. (16295809)
2005
33
Modern imaging of tuberculosis in children: thoracic, central nervous system and abdominal tuberculosis. (15372216)
2004
34
Early detection of central nervous system tuberculosis with the gen-probe nucleic Acid amplification assay: utility in an inner city hospital. (12115103)
2002
35
Diagnostic value of cytokine measurement in cerebrospinal fluid in children with central nervous system tuberculosis. (11388321)
2001
36
Magnetic resonance imaging in diagnosis of childhood central nervous system tuberculosis. (11440385)
2001
37
Central nervous system tuberculosis: imaging manifestations. (10775956)
2000
38
Central nervous system tuberculosis. (10517926)
1999
39
Central nervous system tuberculosis after resolution of miliary tuberculosis. (9655548)
1998
40
Central nervous system tuberculosis--the paradox of the host immune response. (9515661)
1998
41
Auditory disorder in central nervous system miliary tuberculosis: case report. (9733241)
1998
42
Neuroimaging of central nervous system tuberculosis in HIV-infected patients. (9113686)
1997
43
Presumed ocular and central nervous system tuberculosis in a patient with the acquired immunodeficiency syndrome. (8623897)
1996
44
Images in clinical medicine. Miliary tuberculosis involving the central nervous system. (8592551)
1996
45
Paradoxical progression of tuberculous lesions during chemotherapy of central nervous system tuberculosis. Report of four cases. (7616286)
1995
46
Central nervous system tuberculosis in HIV-infected patients: clinical and radiographic findings. (7677034)
1995
47
Central nervous system tuberculosis: MRI. (8183466)
1994
48
Central nervous system tuberculosis in infants and children. (8299041)
1993
49
Central nervous system tuberculosis in children. (1930419)
1991
50
Central nervous system tuberculosis: a persistent disease. (5312859)
1971

Genetic Variations for Central Nervous System Tuberculosis

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Expression for genes affiliated with Central Nervous System Tuberculosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Central Nervous System Tuberculosis

Search GEO for disease gene expression data for Central Nervous System Tuberculosis.

Pathways for genes affiliated with Central Nervous System Tuberculosis

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Compounds for genes affiliated with Central Nervous System Tuberculosis

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GO Terms for genes affiliated with Central Nervous System Tuberculosis

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Products for genes affiliated with Central Nervous System Tuberculosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Central Nervous System Tuberculosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet