MCID: CNT046
MIFTS: 34

Central Nervous System Vasculitis malady

Neuronal diseases, Cardiovascular diseases categories

Summaries for Central Nervous System Vasculitis

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Central Nervous System Vasculitis, also known as vasculitis, central nervous system, is related to vasculitis and central nervous system disease. An important gene associated with Central Nervous System Vasculitis is APP (amyloid beta (A4) precursor protein), and among its related pathways are Integrated Pancreatic Cancer Pathway and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The compounds ndga and c2ceramide have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and spinal cord.

Aliases & Classifications for Central Nervous System Vasculitis

About this section
Sources:
8Disease Ontology, 60UMLS, 39NCIt, 34MeSH
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Cardiovascular diseases


Aliases & Descriptions:

central nervous system vasculitis 8
vasculitis, central nervous system 60


External Ids:

Disease Ontology8 DOID:525
NCIt39 C84622
MeSH34 D020293

Related Diseases for Central Nervous System Vasculitis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Central Nervous System Vasculitis:



Diseases related to central nervous system vasculitis

Clinical Features for Central Nervous System Vasculitis

About this section

Drugs & Therapeutics for Central Nervous System Vasculitis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Central Nervous System Vasculitis

Drug clinical trials:

Search ClinicalTrials for Central Nervous System Vasculitis

Search NIH Clinical Center for Central Nervous System Vasculitis

Search CenterWatch for Central Nervous System Vasculitis

Genetic Tests for Central Nervous System Vasculitis

About this section

Anatomical Context for Central Nervous System Vasculitis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Central Nervous System Vasculitis:

32
Brain, Testes, Spinal cord, Endothelial

Animal Models for Central Nervous System Vasculitis or affiliated genes

About this section

Publications for Central Nervous System Vasculitis

About this section
Sources:
50PubMed
See all sources

Articles related to Central Nervous System Vasculitis:

(show top 50)    (show all 131)
idTitleAuthorsYear
1
Central nervous system-immune reconstitution inflammatory syndrome presenting as varicella zoster virus-mediated vasculitis causing stroke. (24407026)
2014
2
Central Nervous System vasculitis associated with Hepatitis C virus infection: A brain MRI-supported diagnosis. (24211061)
2014
3
L38. How to treat primary vasculitis of the central nervous system. (23465297)
2013
4
Childhood central nervous system vasculitis. (23608691)
2013
5
Central nervous system vasculitis. (23475760)
2013
6
Febrile ulceronecrotic Mucha-Habermann disease with central nervous system vasculitis. (22276640)
2013
7
Circulating endothelial cells as potential diagnostic biomarkers in primary central nervous system vasculitis. (23243263)
2013
8
Primary intraocular central nervous system lymphoma masquerading as diffuse retinal vasculitis. (23632616)
2013
9
Pseudotumoral presentation of primary central nervous system vasculitis. (23689414)
2013
10
Possible central nervous system vasculitis as an early presentation of Crohn's disease. A challenge in diagnosis and management. (22964818)
2012
11
Adult primary central nervous system vasculitis: an update. (22157412)
2012
12
Adult primary central nervous system vasculitis. (22575778)
2012
13
A rare association of localized scleroderma type morphea, vitiligo, autoimmune hypothyroidism, pneumonitis, autoimmune thrombocytopenic purpura and central nervous system vasculitis. Case report. (23256875)
2012
14
Rapidly progressive primary central nervous system vasculitis. (20959356)
2011
15
Isolated central nervous system vasculitis associated with antiribonuclear protein antibody. (22937341)
2011
16
Two uncommon manifestations of leptospirosis: Sweet's syndrome and central nervous system vasculitis. (21771425)
2011
17
Investigation of childhood central nervous system vasculitis: magnetic resonance angiography versus catheter cerebral angiography. (20132140)
2010
18
The role of imaging in the diagnosis of central nervous system vasculitis. (20425011)
2010
19
Primary central nervous system vasculitis: Is it a single disease? (21031572)
2010
20
Angiographic diagnosis of primary central nervous system vasculitis with spinal cord involvement. (19364941)
2009
21
Refractory central nervous system vasculitis and gastrocnemius myalgia syndrome in Crohn's disease successfully treated with anti-tumor necrosis factor-alpha antibody. (18304612)
2009
22
Central nervous system vasculitis. (19908043)
2009
23
Lupus-associated pancreatitis complicated by pancreatic pseudocyst and central nervous system vasculitis. (19074172)
2009
24
Central nervous system vasculitis after starting methimazole in a woman with Graves' disease. (18788922)
2008
25
Primary central nervous system vasculitis with prominent leptomeningeal enhancement: a subset with a benign outcome. (18240248)
2008
26
Angiography-negative primary central nervous system vasculitis: a syndrome involving small cerebral vessels. (18794709)
2008
27
Prominent perivascular enhancement in primary central nervous system vasculitis. (18799067)
2008
28
Primary central nervous system vasculitis in a child mimicking parasitosis. (18204924)
2008
29
10 questions on central nervous system vasculitis. (18332846)
2008
30
Imaging findings of central nervous system vasculitis associated with Goodpasture's Syndrome: a case report. (18071286)
2007
31
Central nervous system vasculitis in children. (17092443)
2006
32
Central nervous system vasculitis secondary to parvovirus B19 infection in a pediatric renal transplant patient. (15747163)
2005
33
Central nervous system involvement in hepatitis C virus cryoglobulinemia vasculitis: a multicenter case-control study using magnetic resonance imaging and neuropsychological tests. (15742440)
2005
34
Angiography-negative primary central nervous system vasculitis in children: a newly recognized inflammatory central nervous system disease. (15986347)
2005
35
Are T1- and T2-weighted spin-echo MR images sufficient for the diagnosis of central nervous system vasculitis? (12076949)
2002
36
Intravenous gammaglobulin in the treatment of central nervous system vasculitis associated with SjAPgren's syndrome. (10782846)
2000
37
A case of central nervous system vasculitis related to an episode of Guillain-BarrA" syndrome. (11056753)
2000
38
Circulating antineutrophil autoantibodies in a child with isolated central nervous system vasculitis. (10598839)
1999
39
Central nervous system vasculitis. (9642543)
1998
40
Pediatric Wegener's granulomatosis complicated by central nervous system vasculitis. (9831006)
1998
41
Classification and histopathologic spectrum of central nervous system vasculitis. (9367965)
1997
42
Evaluation and treatment of central nervous system vasculitis. (7718420)
1995
43
Neuroradiology of central nervous system vasculitis. (7709083)
1994
44
Sensitivities of noninvasive tests for central nervous system vasculitis: a comparison of lumbar puncture, computed tomography, and magnetic resonance imaging. (7966069)
1994
45
Cardiac and central nervous system vasculitis in a child with dermatomyositis. (7930410)
1994
46
Central nervous system vasculitis secondary to infections, toxins, and neoplasms. (7709082)
1994
47
Miscellaneous vasculitic syndromes including BehAset's disease and central nervous system vasculitis. (8435289)
1993
48
Central nervous system vasculitis. (3826768)
1987
49
Cerebral angiography as a guide for therapy in isolated central nervous system vasculitis. (3560402)
1987
50
SjAPgren's syndrome. Association of cutaneous vasculitis with central nervous system disease. (3555358)
1987

Genetic Variations for Central Nervous System Vasculitis

About this section

Expression for genes affiliated with Central Nervous System Vasculitis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Central Nervous System Vasculitis

Search GEO for disease gene expression data for Central Nervous System Vasculitis.

Pathways for genes affiliated with Central Nervous System Vasculitis

About this section
Sources:
37NCBI BioSystems Database, 53Reactome, 29KEGG, 55SinoBiological, 52R&D Systems, 12EMD Millipore
See all sources

Compounds for genes affiliated with Central Nervous System Vasculitis

About this section
Sources:
44Novoseek, 2BitterDB, 49PharmGKB, 28IUPHAR, 11DrugBank, 59Tocris Bioscience, 24HMDB
See all sources

Compounds related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1ndga449.4APP, TNF
2c2ceramide449.4APP, TNF
3chloroquine44 2 49 28 1113.3TNF, APP
4lactacystin449.3APP, TNF
5egcg449.3APP, TNF
6simvastatin44 49 59 28 11 2414.2TNF, APP
7curcumin449.2APP, TNF
8methotrexate44 49 1111.1APP, TNF
9cyclosporin a44 28 5911.1APP, TNF
10butyrate449.0TNF, APP
11actinomycin d448.8APP, TNF

GO Terms for genes affiliated with Central Nervous System Vasculitis

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell surfaceGO:0099869.1APP, TNF

Biological processes related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix organizationGO:0301989.1APP, TNF

Molecular functions related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428029.1APP, TNF

Products for genes affiliated with Central Nervous System Vasculitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Central Nervous System Vasculitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet