MCID: CNT046
MIFTS: 34

Central Nervous System Vasculitis malady

Neuronal diseases, Cardiovascular diseases categories

Summaries for Central Nervous System Vasculitis

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32MalaCards
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MalaCards: Central Nervous System Vasculitis, also known as vasculitis, central nervous system, is related to vasculitis and central nervous system disease. An important gene associated with Central Nervous System Vasculitis is APP (amyloid beta (A4) precursor protein), and among its related pathways are Integrated Pancreatic Cancer Pathway and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The compounds ndga and c2ceramide have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and spinal cord.

Aliases & Classifications for Central Nervous System Vasculitis

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Sources:
8Disease Ontology, 60UMLS, 39NCIt, 34MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Cardiovascular diseases


Aliases & Descriptions:

central nervous system vasculitis 8
vasculitis, central nervous system 60


External Ids:

Disease Ontology8 DOID:525
NCIt39 C84622
MeSH34 D020293

Related Diseases for Central Nervous System Vasculitis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Central Nervous System Vasculitis:



Diseases related to central nervous system vasculitis

Clinical Features for Central Nervous System Vasculitis

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Drugs & Therapeutics for Central Nervous System Vasculitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Central Nervous System Vasculitis

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Anatomical Context for Central Nervous System Vasculitis

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32MalaCards
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MalaCards organs/tissues related to Central Nervous System Vasculitis:

32
Brain, Testes, Spinal cord, Endothelial

Animal Models for Central Nervous System Vasculitis or affiliated genes

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Publications for Central Nervous System Vasculitis

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50PubMed
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Articles related to Central Nervous System Vasculitis:

(show top 50)    (show all 131)
idTitleAuthorsYear
1
Central nervous system-immune reconstitution inflammatory syndrome presenting as varicella zoster virus-mediated vasculitis causing stroke. (24407026)
2014
2
Malignant perivascular melanoma mimicking primary central nervous system vasculitis. (23263476)
2013
3
Central Nervous System Vasculitis. (24435038)
2013
4
Recent understanding on diagnosis and management of central nervous system vasculitis in children. (23008735)
2012
5
von Willebrand factor antigen--a possible biomarker of disease activity in childhood central nervous system vasculitis? (22740622)
2012
6
Refractory primary central nervous system vasculitis of childhood: successful treatment with infliximab. (23118297)
2012
7
Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C. (22253526)
2012
8
Primary central nervous system vasculitis: pathology and mechanisms. (22421812)
2012
9
Fatal exserohilum meningitis and central nervous system vasculitis after cervical epidural methylprednisolone injection. (23277893)
2012
10
Central nervous system vasculitis: all that glitters is not gold. (22383360)
2012
11
Primary central nervous system vasculitis presenting as spinal subdural hematoma. (22120304)
2012
12
Primary central nervous system vasculitis presenting with intracranial hemorrhage. (22038406)
2011
13
Isolated central nervous system vasculitis associated with antiribonuclear protein antibody. (22937341)
2011
14
Central nervous system vasculitis: still more questions than answers. (22379458)
2011
15
Primary central nervous system vasculitis: clinical experiences with 21 new European cases. (20024553)
2011
16
Imaging findings in primary central nervous system vasculitis. (21586204)
2011
17
Central nervous system vasculitis with positive antithyroid antibodies in an adolescent boy. (21824569)
2011
18
Primary central nervous system vasculitis and moyamoya disease: similarities and differences. (20037765)
2010
19
Diagnosing central nervous system vasculitis in children. (21610331)
2010
20
Systemic panca-associated vasculitis with central nervous involvement causing recurrent myelitis: case report. (21118568)
2010
21
Primary central nervous system vasculitis mimicking brain tumour: case report and literature review. (19370353)
2009
22
Angiographic diagnosis of primary central nervous system vasculitis with spinal cord involvement. (19364941)
2009
23
Central nervous system vasculitis. (19908043)
2009
24
Primary central nervous system vasculitis: is biopsy appropriate? (18350582)
2008
25
Brain abscess formation at the site of intracerebral hemorrhage secondary to central nervous system vasculitis. (18518742)
2008
26
Primary central nervous system vasculitis: comparison of patients with and without cerebral amyloid angiopathy. (18753193)
2008
27
Prominent perivascular enhancement in primary central nervous system vasculitis. (18799067)
2008
28
Cerebral vasculopathy does not equal primary central nervous system vasculitis. (18350577)
2008
29
Primary central nervous system vasculitis: analysis of 101 patients. (17924545)
2007
30
Primary central nervous system vasculitis: progress and questions. (18041087)
2007
31
Primary necrotizing lymphocytic central nervous system vasculitis due to perforin deficiency in a four-year-old girl. (17328077)
2007
32
Primary central nervous system vasculitis in children. (16575852)
2006
33
Primary angiitis of the central nervous system: a misinterpreted clinical onset of CNS vasculitis. (15746543)
2005
34
Central nervous system vasculitis caused by propylthiouracil therapy: a case report and literature review. (15687828)
2005
35
Central nervous system involvement in hepatitis C virus cryoglobulinemia vasculitis: a multicenter case-control study using magnetic resonance imaging and neuropsychological tests. (15742440)
2005
36
Central nervous system vasculitis. (12774201)
2003
37
Central nervous system vasculitis. (12628042)
2003
38
Primary angiitis of the central nervous system: the penumbra of vasculitis. (11296942)
2001
39
Central nervous system vasculitis as a complication of refractory dermatomyositis. (11196527)
2001
40
A case of central nervous system vasculitis related to an episode of Guillain-BarrA" syndrome. (11056753)
2000
41
Isolated central nervous system vasculitis associated with hepatitis C infection. (10529155)
1999
42
Central nervous system vasculitis in systemic lupus erythematosus: a case successfully treated with cyclophosphamide and steroids. (19078225)
1997
43
Response of central nervous system vasculitis to irradiation. (1673534)
1991
44
Ephedrine-induced intracerebral hemorrhage and central nervous system vasculitis. (2237962)
1990
45
Plasma concentrations of complement-activation complexes correlate with disease activity in patients diagnosed with isolated central nervous system vasculitis. (2913130)
1989
46
An unusual case of central nervous system vasculitis. (3612207)
1987
47
Florid central nervous system vasculitis in a fatal case of systemic lupus erythematosus. (7175846)
1982
48
Intravascular malignant histiocytosis mimicking central nervous system vasculitis: an immunopathological diagnostic approach. (6758680)
1982
49
Central nervous system vasculitis in cytomegalovirus infection. (6268757)
1981
50
Central nervous system vasculitis in rheumatoid arthritis. (597801)
1977

Genetic Variations for Central Nervous System Vasculitis

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Expression for genes affiliated with Central Nervous System Vasculitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Central Nervous System Vasculitis

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Pathways for genes affiliated with Central Nervous System Vasculitis

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37NCBI BioSystems Database, 53Reactome, 29KEGG, 55SinoBiological, 52R&D Systems, 12EMD Millipore
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Compounds for genes affiliated with Central Nervous System Vasculitis

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44Novoseek, 2BitterDB, 49PharmGKB, 28IUPHAR, 11DrugBank, 59Tocris Bioscience, 24HMDB
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Compounds related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1ndga449.4APP, TNF
2c2ceramide449.4APP, TNF
3chloroquine44 2 49 28 1113.3TNF, APP
4lactacystin449.3APP, TNF
5egcg449.3APP, TNF
6simvastatin44 49 59 28 11 2414.2TNF, APP
7curcumin449.2APP, TNF
8methotrexate44 49 1111.1APP, TNF
9cyclosporin a44 28 5911.1APP, TNF
10butyrate449.0TNF, APP
11actinomycin d448.8APP, TNF

GO Terms for genes affiliated with Central Nervous System Vasculitis

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16Gene Ontology
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Cellular components related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell surfaceGO:0099869.1APP, TNF

Biological processes related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix organizationGO:0301989.1APP, TNF

Molecular functions related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428029.1APP, TNF

Products for genes affiliated with Central Nervous System Vasculitis

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  • Antibodies
  • Proteins
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Sources for Central Nervous System Vasculitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet