MCID: CNT046
MIFTS: 28

Central Nervous System Vasculitis malady

Summaries for Central Nervous System Vasculitis

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33MalaCards
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MalaCards: Central Nervous System Vasculitis, also known as vasculitis, central nervous system, is related to vasculitis and n syndrome. An important gene associated with Central Nervous System Vasculitis is APP (amyloid beta (A4) precursor protein), and among its related pathways are Integrated Pancreatic Cancer Pathway and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The compounds ndga and c2ceramide have been mentioned in the context of this disorder.

Aliases & Classifications for Central Nervous System Vasculitis

Sources:
8Disease Ontology, 61UMLS, 40NCIt, 35MeSH
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Aliases & Descriptions:

central nervous system vasculitis 8
vasculitis, central nervous system 61


External Ids:

Disease Ontology8 DOID:525
NCIt40 C84622
MeSH35 D020293

Related Diseases for Central Nervous System Vasculitis

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Central Nervous System Vasculitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 56)
idRelated DiseaseScoreTop Affiliating Genes
1vasculitis31.9TNF
2n syndrome10.7
3hepatitis c10.5
4hemorrhage, intracerebral10.5
5crohn's disease10.4
6systemic lupus erythematosus10.4
7good syndrome10.4
8goodpasture syndrome10.4
9primary angiitis of the central nervous system10.4
10central retinal artery occlusion10.2
11moyamoya disease10.2
12branch retinal artery occlusion10.2
13familial mediterranean fever10.2
14autoimmune thrombocytopenic purpura10.2
15cerebral arteritis10.2
16arteriovenous malformation10.2
17wegener's granulomatosis10.2
18leptospirosis10.2
19cerebral amyloid angiopathy10.2
20localized scleroderma10.2
21hepatitis b10.2
22hepatitis d10.2
23malignant histiocytosis10.2
24chickenpox10.2
25graves' disease10.2
26vitiligo10.2
27retinal vasculitis10.2
28arthritis10.2
29brain stem infarction10.2
30uveitis10.2
31linear scleroderma10.2
32febrile ulceronecrotic mucha-habermann disease10.2
33lymphocytic vasculitis10.2
34rheumatoid vasculitis10.2
35west nile virus10.2
36guillain-barr� syndrome10.2
37cytomegalovirus infection10.2
38hypothyroidism, autoimmune10.2
39hepatitis c virus10.2
40hepatitis b virus infection10.2
41reversible cerebral vasoconstriction syndrome10.2
42pneumococcal meningitis10.2
43encephalomyelitis10.0TNF
44malaria10.0TNF
45meningoencephalitis10.0APP
46toxic encephalopathy10.0APP
47cerebrovascular disease10.0APP
48tetanus10.0APP
49amyloidosis10.0APP
50encephalitis10.0APP

Graphical network of the top 20 diseases related to Central Nervous System Vasculitis:



Diseases related to central nervous system vasculitis

Clinical Features for Central Nervous System Vasculitis

Drugs & Therapeutics for Central Nervous System Vasculitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Central Nervous System Vasculitis

Drug clinical trials:

Search ClinicalTrials for Central Nervous System Vasculitis

Search NIH Clinical Center for Central Nervous System Vasculitis

Search CenterWatch for Central Nervous System Vasculitis

Genetic Tests for Central Nervous System Vasculitis

Anatomical Context for Central Nervous System Vasculitis

Animal Models for Central Nervous System Vasculitis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Central Nervous System Vasculitis

Sources:
51PubMed
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Articles related to Central Nervous System Vasculitis:

(show top 50)    (show all 131)
idTitleAuthorsYear
1
Central nervous system-immune reconstitution inflammatory syndrome presenting as varicella zoster virus-mediated vasculitis causing stroke. (24407026)
2014
2
L38. How to treat primary vasculitis of the central nervous system. (23465297)
2013
3
Malignant perivascular melanoma mimicking primary central nervous system vasculitis. (23263476)
2013
4
Childhood central nervous system vasculitis. (23608691)
2013
5
Febrile ulceronecrotic Mucha-Habermann disease with central nervous system vasculitis. (22276640)
2013
6
Primary intraocular central nervous system lymphoma masquerading as diffuse retinal vasculitis. (23632616)
2013
7
Central Nervous System Vasculitis. (24435038)
2013
8
von Willebrand factor antigen--a possible biomarker of disease activity in childhood central nervous system vasculitis? (22740622)
2012
9
Adult primary central nervous system vasculitis: an update. (22157412)
2012
10
Adult primary central nervous system vasculitis. (22575778)
2012
11
Fatal exserohilum meningitis and central nervous system vasculitis after cervical epidural methylprednisolone injection. (23277893)
2012
12
Isolated central nervous system vasculitis associated with antiribonuclear protein antibody. (22937341)
2011
13
Primary central nervous system vasculitis: clinical experiences with 21 new European cases. (20024553)
2011
14
Imaging findings in primary central nervous system vasculitis. (21586204)
2011
15
Central nervous system vasculitis with positive antithyroid antibodies in an adolescent boy. (21824569)
2011
16
The role of imaging in the diagnosis of central nervous system vasculitis. (20425011)
2010
17
Systemic panca-associated vasculitis with central nervous involvement causing recurrent myelitis: case report. (21118568)
2010
18
Primary central nervous system vasculitis mimicking brain tumour: case report and literature review. (19370353)
2009
19
Angiographic diagnosis of primary central nervous system vasculitis with spinal cord involvement. (19364941)
2009
20
Central nervous system vasculitis. (19908043)
2009
21
Brain abscess formation at the site of intracerebral hemorrhage secondary to central nervous system vasculitis. (18518742)
2008
22
Central nervous system vasculitis after starting methimazole in a woman with Graves' disease. (18788922)
2008
23
Primary central nervous system vasculitis: comparison of patients with and without cerebral amyloid angiopathy. (18753193)
2008
24
Prominent perivascular enhancement in primary central nervous system vasculitis. (18799067)
2008
25
Primary central nervous system vasculitis in a child mimicking parasitosis. (18204924)
2008
26
10 questions on central nervous system vasculitis. (18332846)
2008
27
Primary central nervous system vasculitis: analysis of 101 patients. (17924545)
2007
28
Imaging findings of central nervous system vasculitis associated with Goodpasture's Syndrome: a case report. (18071286)
2007
29
Primary necrotizing lymphocytic central nervous system vasculitis due to perforin deficiency in a four-year-old girl. (17328077)
2007
30
Primary central nervous system vasculitis in children. (16575852)
2006
31
Primary angiitis of the central nervous system: a misinterpreted clinical onset of CNS vasculitis. (15746543)
2005
32
Central nervous system involvement in hepatitis C virus cryoglobulinemia vasculitis: a multicenter case-control study using magnetic resonance imaging and neuropsychological tests. (15742440)
2005
33
Central nervous system vasculitis. (12628042)
2003
34
Intravenous gammaglobulin in the treatment of central nervous system vasculitis associated with SjAPgren's syndrome. (10782846)
2000
35
A case of central nervous system vasculitis related to an episode of Guillain-BarrA" syndrome. (11056753)
2000
36
Isolated central nervous system vasculitis associated with hepatitis C infection. (10529155)
1999
37
Circulating antineutrophil autoantibodies in a child with isolated central nervous system vasculitis. (10598839)
1999
38
Central nervous system vasculitis. (9642543)
1998
39
Central nervous system vasculitis in systemic lupus erythematosus: a case successfully treated with cyclophosphamide and steroids. (19078225)
1997
40
Sensitivities of noninvasive tests for central nervous system vasculitis: a comparison of lumbar puncture, computed tomography, and magnetic resonance imaging. (7966069)
1994
41
Miscellaneous vasculitic syndromes including BehAset's disease and central nervous system vasculitis. (8435289)
1993
42
Response of central nervous system vasculitis to irradiation. (1673534)
1991
43
Plasma concentrations of complement-activation complexes correlate with disease activity in patients diagnosed with isolated central nervous system vasculitis. (2913130)
1989
44
Central nervous system vasculitis. (3826768)
1987
45
An unusual case of central nervous system vasculitis. (3612207)
1987
46
SjAPgren's syndrome. Association of cutaneous vasculitis with central nervous system disease. (3555358)
1987
47
Florid central nervous system vasculitis in a fatal case of systemic lupus erythematosus. (7175846)
1982
48
Intravascular malignant histiocytosis mimicking central nervous system vasculitis: an immunopathological diagnostic approach. (6758680)
1982
49
Central nervous system vasculitis in cytomegalovirus infection. (6268757)
1981
50
Central nervous system vasculitis in rheumatoid arthritis. (597801)
1977

Genetic Variations for Central Nervous System Vasculitis

Expression for genes affiliated with Central Nervous System Vasculitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Central Nervous System Vasculitis

Search GEO for disease gene expression data for Central Nervous System Vasculitis.

Pathways for genes affiliated with Central Nervous System Vasculitis

Sources:
38NCBI BioSystems Database, 54Reactome, 30KEGG, 56SinoBiological, 53R&D Systems, 12EMD Millipore
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Compounds for genes affiliated with Central Nervous System Vasculitis

Sources:
45Novoseek, 2BitterDB, 50PharmGKB, 29IUPHAR, 11DrugBank, 60Tocris Bioscience, 24HMDB
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Compounds related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1ndga459.4APP, TNF
2c2ceramide459.4APP, TNF
3chloroquine45 2 50 29 1113.3TNF, APP
4lactacystin459.3APP, TNF
5egcg459.3APP, TNF
6simvastatin45 50 60 29 11 2414.2TNF, APP
7curcumin459.2APP, TNF
8methotrexate45 50 1111.1APP, TNF
9cyclosporin a45 29 6011.1APP, TNF
10butyrate459.0TNF, APP
11actinomycin d458.8APP, TNF

GO Terms for genes affiliated with Central Nervous System Vasculitis

Sources:
16Gene Ontology
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Cellular components related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell surfaceGO:0099869.1APP, TNF

Biological processes related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrix organizationGO:0301989.1APP, TNF

Molecular functions related to Central Nervous System Vasculitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428029.1APP, TNF

Products for genes affiliated with Central Nervous System Vasculitis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Central Nervous System Vasculitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet