MCID: CNT015
MIFTS: 43

Central Sleep Apnea

Categories: Mental diseases

Aliases & Classifications for Central Sleep Apnea

MalaCards integrated aliases for Central Sleep Apnea:

Name: Central Sleep Apnea 12 14
Central Sleep Apnea Syndrome 12 69
Sleep Apnea, Central 42 69
Central Sleep Apnea, Primary 69
Primary Central Sleep Apnea 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9220
ICD10 33 G47.31
ICD9CM 35 327.21
MeSH 42 D020182
SNOMED-CT 64 9741000119101
UMLS 69 C0751762

Summaries for Central Sleep Apnea

Disease Ontology : 12 A sleep apnea that is characterized by a malfunction of the basic neurological controls for breathing rate and the failure to give the signal to inhale, causing the individual to miss one or more cycles of breathing.

MalaCards based summary : Central Sleep Apnea, also known as central sleep apnea syndrome, is related to sleep apnea and idiopathic alveolar hypoventilation syndrome. An important gene associated with Central Sleep Apnea is NPPB (Natriuretic Peptide B), and among its related pathways/superpathways are Prolactin Signaling Pathway and AGE/RAGE pathway. The drugs Dexlansoprazole and Lansoprazole have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and kidney.

Wikipedia : 72 Central sleep apnea (CSA) or central sleep apnea syndrome (CSAS) is a sleep-related disorder in which... more...

Related Diseases for Central Sleep Apnea

Diseases in the Sleep Apnea family:

Central Sleep Apnea

Diseases related to Central Sleep Apnea via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
id Related Disease Score Top Affiliating Genes
1 sleep apnea 11.5
2 idiopathic alveolar hypoventilation syndrome 11.1
3 synovial chondromatosis 10.5 NPPA NPPB
4 vascular erectile tumor 10.5 NPPA NPPB
5 american histoplasmosis 10.5 NPPA NPPB
6 idiopathic juxtafoveal retinal telangiectasia 10.4 NPPA NPPB
7 suppurative otitis media 10.4 NPPA NPPB
8 placental abruption 10.4 HSPB7 NPPB
9 congestive heart failure 10.4
10 urinary bladder posterior wall cancer 10.3 NPPA NPPB
11 lethal congenital contractural syndrome 2 10.3 NOS3 NPPB
12 ophthalmia neonatorum 10.3 NOS3 NPPB
13 clitoris cancer 10.3 NOS3 NPPA
14 epithelial predominant pulmonary blastoma 10.3 NOS3 NPPA
15 trichinosis 10.3 NOS3 NPPB
16 islet cell tumor 10.3 NOS3 NPPB
17 obstructive sleep apnea 10.2
18 lymphadenitis 10.2 NOS3 NPPA
19 pyelonephritis 10.1 NOS3 NPPB
20 thoracic spinal canal and spinal cord meningioma 10.1 NOS3 NPPA
21 ichthyosis lamellar 2 10.1 LEP NPPA NPPB
22 atrial fibrillation 10.0
23 3-hydroxyisobutryl-coa hydrolase deficiency 10.0 LEP NPPA
24 myxomatous pattern testicular yolk sac tumor 10.0 CA1 NOS3
25 systolic heart failure 10.0
26 chiari malformation 10.0
27 cardiomyopathy 10.0
28 preeclampsia/eclampsia 1 10.0 LEP NOS3
29 diabetic encephalopathy 9.9 LEP NOS3
30 pulmonary hypertension 9.9
31 dilated cardiomyopathy 9.9
32 heart disease 9.9
33 kidney disease 9.9
34 periampullary adenoma 9.9 LEP NOS3 NPPB
35 hypertrichosis 9.9 LEP NOS3
36 stiff-person syndrome 9.9
37 hypothyroidism 9.9
38 pharyngitis 9.9
39 cervicitis 9.9
40 cerebritis 9.9
41 sleep disorder 9.9
42 craniosynostosis 7 9.8 NPPA NPPB
43 myocardial infarction 9.7
44 obesity 9.7
45 hyperprolactinemia 9.7
46 vici syndrome 9.7
47 laryngomalacia 9.7
48 atherosclerosis 9.7
49 craniosynostosis 9.7
50 leukemia 9.7

Graphical network of the top 20 diseases related to Central Sleep Apnea:



Diseases related to Central Sleep Apnea

Symptoms & Phenotypes for Central Sleep Apnea

Drugs & Therapeutics for Central Sleep Apnea

Drugs for Central Sleep Apnea (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 268)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexlansoprazole Approved Phase 4 138530-94-6, 103577-45-3 9578005
2
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
3
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2 2078-54-8 4943
4
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 1 437-38-7 3345
5
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 57-27-2 5288826
6
Acetaminophen Approved Phase 4 103-90-2 1983
7
Eszopiclone Approved Phase 4,Phase 2,Early Phase 1 138729-47-2 969472
8
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
9
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
10
Losartan Approved Phase 4 114798-26-4 3961
11
Adalimumab Approved Phase 4 331731-18-1 16219006
12
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
13
Acetazolamide Approved, Vet_approved Phase 4,Phase 3,Phase 2 59-66-5 1986
14
Armodafinil Approved, Investigational Phase 4,Phase 3 112111-43-0
15
Modafinil Approved, Investigational Phase 4,Phase 3 68693-11-8 4236
16
Sodium oxybate Approved Phase 4 502-85-2 5360545
17
Zolpidem Approved Phase 4 82626-48-0 5732
18
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
19
Budesonide Approved Phase 4 51333-22-3 63006 5281004
20
Phentermine Approved, Illicit Phase 4 122-09-8 4771
21
Topiramate Approved Phase 4 97240-79-4 5284627
22
Donepezil Approved Phase 4 120014-06-4 3152
23
Zopiclone Approved Phase 4,Phase 3 43200-80-2 5735
24
Remifentanil Approved Phase 4 132875-61-7 60815
25
Menthol Approved Phase 4,Phase 3,Phase 1,Phase 2 2216-51-5 16666
26
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
27
Desflurane Approved Phase 4 57041-67-5 42113
28
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
29
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
30
Trazodone Approved, Investigational Phase 4,Phase 2,Phase 1 19794-93-5 5533
31
Carbidopa Approved Phase 4 28860-95-9 34359 38101
32
Levodopa Approved Phase 4 59-92-7 6047
33
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
34
Finasteride Approved Phase 4 98319-26-7 57363
35
Testosterone Approved, Investigational Phase 4 58-22-0 6013
36
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
37
Guaifenesin Approved, Vet_approved Phase 4 93-14-1 3516
38
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
39
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
40
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
41
Loperamide Approved Phase 4 53179-11-6 3955
42
Opium Approved, Illicit Phase 4 8008-60-4
43 tannic acid Approved, Nutraceutical Phase 4
44
Angiotensin II Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
45 Antacids Phase 4
46 Anti-Ulcer Agents Phase 4
47 Gastrointestinal Agents Phase 4,Phase 1,Phase 2
48
Proton pump inhibitors Phase 4
49 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
50 Hypnotics and Sedatives Phase 4,Phase 3,Phase 2,Early Phase 1

Interventional clinical trials:

(show top 50) (show all 592)

id Name Status NCT ID Phase Drugs
1 Comparison of the Pentax AWS® With the Macintosh Laryngoscopic Intubation in Obstructive Sleep Apnea Syndrome Patients Unknown status NCT01428570 Phase 4
2 Dexlansoprazole to Treat Laryngopharyngeal Reflux and Lingual Tonsil Hypertrophy Unknown status NCT01328652 Phase 4 dexlansoprazole
3 Cardiac Resynchronisation Therapy in Combination With Overdrive Pacing in the Treatment of Central Sleep Apnea in CHF Completed NCT00551499 Phase 4
4 Treatment of Predominant Central Sleep Apnoea by Adaptive Servo Ventilation in Patients With Heart Failure Completed NCT00733343 Phase 4
5 Substudy on the Mechanistic Plausibility of the Clinical Benefits of Adaptive Servo-ventilation Completed NCT01164592 Phase 4
6 Sleep Apnea. Concordance Between Non-reference and Reference Centres Completed NCT00424658 Phase 4
7 Continuous Positive Airway Pressure (CPAP) Promotion And Prognosis - the Army Sleep Apnea Program (ASAP) Completed NCT00612157 Phase 4 Eszopiclone;Placebo control
8 CPAP in SAHS Patients With Hypertension Completed NCT02398032 Phase 4
9 Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea Completed NCT01344759 Phase 4 Dexmedetomidine;Propofol
10 Ezopiclone Improves the Quality of Overnight Polysomnography Completed NCT00507117 Phase 4 Lunesta;Placebo control
11 Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) Treatment Completed NCT00701428 Phase 4 Losartan
12 Efficacy and Safety of Adalimumab in Patients With Psoriasis and Obstructive Sleep Apnea Completed NCT01181570 Phase 4 Adalimumab;Placebo
13 Continuous Positive Airway Pressure and Acetazolamide to Treat Sleep Apnea Syndrome Patients at Altitude Completed NCT00928655 Phase 4 acetazolamide;placebo
14 Treatment of Sleep Disordered Breathing In Acute Decompensated Heart Failure Patients Completed NCT00804349 Phase 4
15 Trial of Effects of Oral Xyrem and Zolpidem on Sleep-Disordered Breathing in Obstructive Sleep Apnea Patients Completed NCT00086281 Phase 4 Xyrem (X);Zolpidem (Z);Modafinil (M);Placebo (P)
16 Serotonin and the Upper Airway in Obstructive Sleep Apnea Completed NCT00100464 Phase 4 Paroxetine;5HTP
17 Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome Completed NCT00560586 Phase 4 Budesonide;placebo
18 A Toolbox Approach to Obesity Treatment in Primary Care Completed NCT01922934 Phase 4 Obesity pharmacotherapy
19 "Pilot Study of Armodafinil in Patients With Dementia With Lewy Bodies" Completed NCT01023672 Phase 4 Armodafinil
20 The Effects of Mometasone Furoate Nasal Spray in Subjects With Sleep-disordered Breathing (SDB) Associated With Perennial Allergic Rhinitis (Study P04726) Completed NCT00359216 Phase 4 Mometasone furoate nasal spray;Placebo
21 Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression Completed NCT00518986 Phase 4 armodafinil;placebo
22 An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia Fatigue Completed NCT00678691 Phase 4 armodafinil;placebo
23 Study to Determine the Effectiveness of Pillar Palatal Implants to Treat Obstructive Sleep Apnea Completed NCT00307957 Phase 4
24 The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients Completed NCT00480870 Phase 4 donepezil;Placebo
25 Benefit of One Month Zopiclone Intake on Adaptative Servoventilation Compliance Recruiting NCT02820441 Phase 4 Zopiclone;Placebo
26 Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome Recruiting NCT03031626 Phase 4
27 Effect of Adaptive Servo Ventilation (ASV) on Survival and Hospital Admissions in Heart Failure Recruiting NCT01128816 Phase 4
28 Short Life Agents in Balanced Anesthesia on Obstructive Sleep Apnea Syndrome Recruiting NCT02717780 Phase 4 Fentanyl and sevoflurane;Remifentanil and desflurane
29 Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury Recruiting NCT02922894 Phase 4 Trazodone;Placebo
30 Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep Apnea Recruiting NCT02494102 Phase 4 Modafinil;Placebo
31 Effect of Long-acting Levodopa on Obstructive Sleep Apnea in Parkinson's Disease Recruiting NCT03111485 Phase 4 Sinemet CR;Placebo oral capsule
32 Auto-PAP for Pulmonary Hypertension Treatment in Decompensated HF Patients With Sleep Apnea. Recruiting NCT02963597 Phase 4
33 CPAP Effect on the Progression of Diabetic Retinopathy in Patients With Sleep Apnea Recruiting NCT02874313 Phase 4 Pharmacological treatment
34 Oxygen Versus PAP for Sleep Apnea in Heart Failure Recruiting NCT01807897 Phase 4
35 Impact of Intrathecal Morphine on Sleep Apnea Syndrome Recruiting NCT02566226 Phase 4 Bupivacaine with normal saline;Bupivacaine with intrathecal morphine
36 Sleep Apnea in Elderly Recruiting NCT02703220 Phase 4 Acetazolamide;Finasteride
37 Somnodent vs Herbst in Mild and Moderate OSA Patients Recruiting NCT02724865 Phase 4
38 Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy Recruiting NCT02425202 Phase 4 Ketamine
39 Post-tonsillectomy Pain Control in Adults Recruiting NCT02358850 Phase 4 Norco (Hydrocodone and Acetaminophen);Percocet (Oxycodone and Acetaminophen);Dilaudid (hydromorphone);Tylenol (Acetaminophen)
40 Effect of Acetazolamide on Central Sleep Apnea Related to Opium Consumption Enrolling by invitation NCT02371473 Phase 4 Acetazolamide-placebo;Placebo-acetazolamide
41 Oral Appliance in Obstructive Sleep Apnea. A Randomized Controlled Blinded Multicenter Study Comparing Two Devices Enrolling by invitation NCT02148510 Phase 4
42 Nocturnal Oxygen Needs and Central Sleep Apnea in Patients With Chronic Heart Failure. Not yet recruiting NCT03254212 Phase 4
43 Effect Of Early C-PAP Treatment For Sleep Apnea On Rehabilitation Of Stroke Patients Not yet recruiting NCT02426424 Phase 4
44 Decreasing Post-operative Complications of Obstructive Sleep Apnea by Introducing an Intensified Monitoring and Care Protocol Not yet recruiting NCT03281408 Phase 4 Intra-operative: Sedation Techniques
45 Donepezil, Residual Excessive Daytime Sleepiness, Obstructive Sleep Apnea Not yet recruiting NCT03299257 Phase 4 donepezil treatment
46 Ramelteon for Complex Insomnia in Veterans With PTSD Not yet recruiting NCT03265951 Phase 4 Ramelteon
47 Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea Terminated NCT00730041 Phase 4
48 Outcome of IV Acetaminophen Use in Laparoscopic Cholecystectomies in Patients at Risk of OSA Withdrawn NCT02056678 Phase 4 acetaminophen, IV preparation
49 Intranasal Steroids for the Treatment of Nocturnal Enuresis With Associated Obstructive Sleep Apnea Withdrawn NCT01861145 Phase 4 Nasonex
50 Bilevel Positive Pressure Ventilation (BIPAP)in Patients With Sleep Disorders Breathing (SDB)and Congestive Heart Failure (CHF):Comparison of Two Diagnostic Methods Unknown status NCT01501734 Phase 3

Search NIH Clinical Center for Central Sleep Apnea

Cochrane evidence based reviews: sleep apnea, central

Genetic Tests for Central Sleep Apnea

Anatomical Context for Central Sleep Apnea

MalaCards organs/tissues related to Central Sleep Apnea:

39
Heart, Testes, Kidney, Brain, Lung, Endothelial, Liver

Publications for Central Sleep Apnea

Articles related to Central Sleep Apnea:

(show top 50) (show all 299)
id Title Authors Year
1
Respiratory drive in patients with chronic heart failure and central sleep apnea: Data from the Daunia Heart Failure Registry. ( 28065692 )
2017
2
Association between central sleep apnea and left ventricular structure: the Multi-Ethnic Study of Atherosclerosis. ( 28220556 )
2017
3
Sleep Complaints and Sleep Architecture in Children With Idiopathic Central Sleep Apnea. ( 28212689 )
2017
4
Non-Mask-based Therapies for Central Sleep Apnea in Patients with Heart Failure. ( 28477779 )
2017
5
Evaluation of the central sleep apnea in asymptomatic children with Chiari 1 malformation: an open question. ( 28382434 )
2017
6
Predominant obstructive or central sleep apnea in patients with atrial fibrillation: influence of characterizing apneas versus apneas and hypopneas. ( 28899542 )
2017
7
Central sleep apnea: the problem of diagnosis. ( 28153696 )
2017
8
Obstructive and Central Sleep Apnea and the Risk of Incident Atrial Fibrillation in a Community Cohort of Men and Women. ( 28668820 )
2017
9
Impairment of pulmonary diffusion correlates with hypoxemic burden in central sleep apnea heart failure patients. ( 28467884 )
2017
10
Central Sleep Apnea in Patients with Congestive Heart Failure. ( 28477776 )
2017
11
Central Sleep Apnea and Stiff Person Syndrome: A Case Report. ( 28358591 )
2017
12
Central Sleep Apnea in Heart Failure: Sleeping With the Wrong Enemy? ( 28335842 )
2017
13
Rapid-eye-movement sleep-predominant central sleep apnea relieved by positive airway pressure: a case report. ( 28483860 )
2017
14
Focus on Functional Delayed Central Sleep Apnea Following Cervical Laminectomy. An Example of Respiratory Dysfunction in Restorative Neurosurgical Procedures. ( 28120077 )
2017
15
Trajectories of Emergent Central Sleep Apnea During CPAP Therapy. ( 28629918 )
2017
16
Low leptin concentration may identify heart failure patients with central sleep apnea. ( 28643476 )
2017
17
Long-Term Experience with First-Generation Implantable Neurostimulation Device in Central Sleep Apnea Treatment. ( 28211952 )
2017
18
Sympathetic nervous system, systolic heart failure, and central sleep apnea: Are we about to find the missing link? ( 27457530 )
2016
19
Relationship between chronic kidney disease and central sleep apnea: the importance of volume management. ( 27638723 )
2016
20
Adaptive Servo-Ventilation for Central Sleep Apnea in Heart Failure. ( 26886534 )
2016
21
Updated Adaptive Servo-Ventilation Recommendations for the 2012 AASM Guideline: "The Treatment of Central Sleep Apnea Syndromes in Adults: Practice Parameters with an Evidence-Based Literature Review and Meta-Analyses". ( 27092695 )
2016
22
Prognostic Importance of Novel Oxygen Desaturation Metrics in Patients with Heart Failure and Central Sleep Apnea. ( 27615064 )
2016
23
Ischemic Lesion Formation in Solitary Tract Nuclei During Central Sleep Apnea With Heart Failurea88- Reply. ( 26948866 )
2016
24
Novel Therapies for the Treatment of Central Sleep Apnea. ( 27236059 )
2016
25
Adaptive Servo-Ventilation for Central Sleep Apnea in Heart Failure. ( 26886533 )
2016
26
Current treatment approaches and trials in central sleep apnea. ( 26961738 )
2016
27
A novel therapeutic approach for central sleep apnea: Phrenic nerve stimulation by the remedA9Ar System. ( 26964705 )
2016
28
A systematic review on prevalence and risk factors associated with treatment- emergent central sleep apnea. ( 27512510 )
2016
29
End-Tidal CO2 Tension Is Predictive of Effective Nocturnal Oxygen Therapy in Patients with Chronic Heart Failure and Central Sleep Apnea. ( 27169493 )
2016
30
Association between polymorphisms of the HSPB7 gene and Cheyne-Stokes respiration with central sleep apnea in patients with dilated cardiomyopathy and congestive heart failure. ( 27441470 )
2016
31
A review of preventing central sleep apnea by inspired CO2. ( 27093535 )
2016
32
The effect of adaptive servo ventilation (ASV) on objective and subjective outcomes in Cheyne-Stokes respiration (CSR) with central sleep apnea (CSA) in heart failure (HF): A systematic review. ( 26995256 )
2016
33
High Coronary Heart Disease Risk in Hemodialysis Patients with Central Sleep Apnea: A Pilot Study. ( 27771703 )
2016
34
Adaptive Servo-Ventilation for Central Sleep Apnea in Heart Failure. ( 26886531 )
2016
35
Central Sleep Apnea at High Altitude. ( 27343103 )
2016
36
Clinical predictors of central sleep apnea evoked by positive airway pressure titration. ( 27555802 )
2016
37
Medium Increased Risk for Central Sleep Apnea but Not Obstructive Sleep Apnea in Long-Term Opioid Users: A Systematic Review and Meta-Analysis. ( 26943709 )
2016
38
Probing the prevalence of central sleep apnea in patients with chronic kidney disease. ( 27638724 )
2016
39
Adaptive Servo-Ventilation for Central Sleep Apnea in Heart Failure. ( 26886532 )
2016
40
Central sleep apnea in multiple sclerosis: a pilot study. ( 27975178 )
2016
41
Severe Central Sleep Apnea Associated WithA Chronic Baclofen Therapy: A Case Series. ( 27157226 )
2016
42
Relationship between central sleep apnea and Cheyne-Stokes Respiration. ( 26961739 )
2016
43
Association of Central Sleep Apnea with Impaired Heart Structure and Cardiovascular Hemodynamics in Patients with Chronic Heart Failure. ( 27558771 )
2016
44
Ischemic Lesion Formation in Solitary Tract Nuclei During Central Sleep Apnea With Heart Failure - Reply -a88Adaptive Servo-Ventilation Therapy for Patients With Chronic Heart Failure in a Confirmatory, Multicenter, Randomized, Controlled Study. ( 26948865 )
2016
45
Congestive Heart Failure and Central Sleep Apnea. ( 26972039 )
2016
46
Is servoventilation in central sleep apnea syndrom still working?. ( 27209837 )
2016
47
Vertex Rolandic Spikes and Central Sleep Apnea inA aA Newborn. ( 27137362 )
2016
48
Central sleep apnea in children: experience at a single center. ( 27823711 )
2016
49
Adaptive Servo-Ventilation for Central Sleep Apnea in Heart Failure. ( 26894248 )
2016
50
Ischemic Lesion Formation in Solitary Tract Nuclei During Central Sleep Apnea With Heart Failure. ( 26948864 )
2016

Variations for Central Sleep Apnea

Expression for Central Sleep Apnea

Search GEO for disease gene expression data for Central Sleep Apnea.

Pathways for Central Sleep Apnea

GO Terms for Central Sleep Apnea

Cellular components related to Central Sleep Apnea according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 caveola GO:0005901 8.62 NOS3 SRC

Biological processes related to Central Sleep Apnea according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 response to insulin GO:0032868 9.54 LEP NPPA
2 response to nutrient levels GO:0031667 9.52 LEP SRC
3 response to drug GO:0042493 9.51 KCNK3 SRC
4 cGMP biosynthetic process GO:0006182 9.49 NPPA NPPB
5 regulation of nitric-oxide synthase activity GO:0050999 9.48 LEP NOS3
6 response to hypoxia GO:0001666 9.46 LEP NPPA
7 positive regulation of insulin receptor signaling pathway GO:0046628 9.4 LEP SRC
8 regulation of vascular permeability GO:0043114 9.37 NPPB SRC
9 receptor guanylyl cyclase signaling pathway GO:0007168 9.32 NPPA NPPB
10 ovulation from ovarian follicle GO:0001542 9.16 LEP NOS3
11 cell growth involved in cardiac muscle cell development GO:0061049 9.13 NPPA
12 regulation of blood vessel size GO:0050880 9.13 NOS3 NPPA NPPB
13 negative regulation of systemic arterial blood pressure GO:0003085 8.96 NPPA
14 regulation of blood pressure GO:0008217 8.92 LEP NOS3 NPPA NPPB

Molecular functions related to Central Sleep Apnea according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.46 LEP NPPA NPPB SRC
2 protein C-terminus binding GO:0008022 9.43 HSPB7 KCNK3 SRC
3 scaffold protein binding GO:0097110 9.32 NOS3 SRC
4 hormone activity GO:0005179 9.13 LEP NPPA NPPB
5 peptide hormone receptor binding GO:0051428 8.62 LEP NPPA

Sources for Central Sleep Apnea

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
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48 NDF-RT
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52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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