MCID: CRB027
MIFTS: 35

Cerebellar Disease malady

Summaries for Cerebellar Disease

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32MalaCards
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MalaCards: Cerebellar Disease, also known as cerebellar deficiency syndrome, is related to movement disease and eye disease. An important gene associated with Cerebellar Disease is NDUFA4 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa). Affiliated tissues include cortex, eye and brain, and related mouse phenotype skeleton.

Aliases & Classifications for Cerebellar Disease

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8Disease Ontology, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

cerebellar disease 8
cerebellar deficiency syndrome 8
cerebellar dysfunction 44
cerebellar disorder 8
cerebellar diseases 60


External Ids:

Disease Ontology8 DOID:2786
MeSH34 D002526

Related Diseases for Cerebellar Disease

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Cerebellar Disease:



Diseases related to cerebellar disease

Clinical Features for Cerebellar Disease

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Drugs & Therapeutics for Cerebellar Disease

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Cerebellar Disease

Search NIH Clinical Center for Cerebellar Disease

Search CenterWatch for Cerebellar Disease

Genetic Tests for Cerebellar Disease

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Anatomical Context for Cerebellar Disease

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32MalaCards
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MalaCards organs/tissues related to Cerebellar Disease:

32
Cortex, Eye, Brain, Testes, Heart, Cerebellum, Thyroid, Thalamus, Ovary, Liver, Bone marrow, Bone, Tongue

Animal Models for Cerebellar Disease or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Cerebellar Disease:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.8ATXN7, PHF14, SATB2

Publications for Cerebellar Disease

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50PubMed
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Articles related to Cerebellar Disease:

(show top 50)    (show all 288)
idTitleAuthorsYear
1
Marked inhibition of Na+, K(+)- ATPase activity and the respiratory chain by phytanic acid in cerebellum from young rats: possible underlying mechanisms of cerebellar ataxia in Refsum disease. (23151916)
2013
2
Teaching NeuroImages: Rosai-Dorfman disease presenting with progressive early-onset cerebellar ataxia. (23897881)
2013
3
Cerebellar ataxia as the first manifestation of Alexander's disease. (22510744)
2012
4
Cerebellar ataxia rehabilitation trial in degenerative cerebellar diseases. (22140200)
2012
5
Unusual presentation in adult medulloblastomas: imaging features mimicking cerebellar dysplastic gangliocytoma (Lhermitte-Duclos disease). (23135053)
2012
6
Dichotic listening test in patients with chronic cerebellar disease. (22133971)
2012
7
Loss of intrinsic organization of cerebellar networks in spinocerebellar ataxia type 1: correlates with disease severity and duration. (20886327)
2011
8
Longitudinal tracking of gait and balance impairments in cerebellar disease. (20544808)
2010
9
Long-term effects of coordinative training in degenerative cerebellar disease. (20737551)
2010
10
Loss of cerebellar granule neurons is associated with punctate but not with large focal deposits of prion protein in Creutzfeldt-Jakob disease. (19606064)
2009
11
Intensive coordinative training improves motor performance in degenerative cerebellar disease. (19864636)
2009
12
Cerebellar anaplastic astrocytoma in a teenager with Ollier Disease. (18414790)
2008
13
Cerebellar alpha-synuclein levels are decreased in Parkinson's disease and do not correlate with SNCA polymorphisms associated with disease in a Swedish material. (18606870)
2008
14
Clinical symptoms of cerebellar disease and their interpretation. (18041661)
2007
15
Anti-GAD antibody cerebellar ataxia mimicking Creutzfeldt-Jakob disease. (16621241)
2007
16
Paraneoplastic cerebellar degeneration associated with anti-neuronal anti-Tr antibodies in a patient with Hodgkin's disease. (17065013)
2006
17
Expression of Toll-like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseases. (16877304)
2006
18
Sporadic Creutzfeldt-Jakob disease with cerebellar ataxia at onset in the UK. (16835290)
2006
19
Selectively increased sensitivity of cerebellar granule cells to AMPA receptor-mediated excitotoxicity in a mouse model of Batten disease. (16483786)
2006
20
Asymmetry of the pitch vestibulo-ocular reflex in patients with cerebellar disease. (15826988)
2005
21
Cognitive impairment and psychiatric symptoms in 133 patients with diseases associated with cerebellar degeneration. (14990766)
2004
22
Lhermitte-Duclos disease (dysplastic cerebellar gangliocytoma): a malformation, hamartoma or neoplasm? (11886354)
2002
23
Niemann-Pick disease type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles. (12505421)
2002
24
Coeliac disease in patients with cerebellar ataxia of unknown origin. (11585106)
2001
25
Metastasis of clear-cell renal carcinoma to cerebellar hemangioblastoma in von Hippel Lindau disease: rare or not investigated? (11685614)
2001
26
Cerebellar ataxia, anterior horn cell disease, learning difficulties, and dystonia: a new syndrome. (11104351)
2000
27
Neuropathological study of cerebellar degeneration in prion disease. (19519645)
1999
28
A reversible neuronal antibody (anti-Tr) associated paraneoplastic cerebellar degeneration in Hodgkin's disease. (9858108)
1998
29
Case 21-1997: Paraneoplastic cerebellar degeneration and Hodgkin's disease. (9424575)
1998
30
Erdheim-Chester disease with extensive intraaxial brain stem lesions presenting as a progressive cerebellar syndrome. (9613758)
1998
31
Camurati-Engelmann disease: two case reports describing metadiaphyseal dysplasia associated with cerebellar ataxia. (9661085)
1998
32
Orthostatic tremor associated with a pontine lesion or cerebellar disease. (9748075)
1998
33
A speaking task analysis of the dysarthria in cerebellar disease. (9197089)
1997
34
Erdheim-Chester disease and slowly progressive cerebellar dysfunction. (7876861)
1995
35
Paraneoplastic cerebellar degeneration in association with Hodgkin's disease: a report of two cases. (8610480)
1995
36
Paraneoplastic cerebellar degeneration: a rare presentation of Hodgkin's disease. (7537642)
1994
37
Procedural learning in Parkinson's disease and cerebellar degeneration. (8215247)
1993
38
A quantitative study of eye and head movements during smooth pursuit in patients with cerebellar disease. (1422792)
1992
39
Coeliac disease presenting with cerebellar degeneration. (1775412)
1991
40
Modified Bielschowsky and immunocytochemical studies on cerebellar plaques in Alzheimer's disease. (1688924)
1990
41
On the role of feedback in maintaining constant grip force in patients with cerebellar disease. (2725958)
1989
42
Cerebellar disease in an adult cow. (17422607)
1986
43
The mechanism for equilibration and sway of the center of gravity in neurological diseases. Effect of the plantar pressure receptor on body sway in spino-cerebellar degeneration. (7294287)
1980
44
Acoustic characteristics of dysarthria associated with cerebellar disease. (502519)
1979
45
Alcoholic cerebellar disease and seizures. (1265622)
1976
46
Cerebellar hypoplasia in Werdnig-Hoffmann disease. (1158057)
1975
47
Flutterlike oscillations of the eyes in cerebellar disease. (13948686)
1963
48
Neurosurgical alleviation of intention tremor of multiple sclerosis and cerebellar disease. (13811793)
1960
49
Neurosurgical relief of intention tremor due to cerebellar disease and multiple sclerosis. (13811794)
1960
50
CASE of CEREBELLAR ABSCESS FOLLOWING MIDDLE-EAR DISEASE: Failure of Respiration during Administration of Anaesthetic: Trephining: Restoration of Respiratory Function for Nearly Thirty Hours: Death. (20760871)
1903

Genetic Variations for Cerebellar Disease

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Expression for genes affiliated with Cerebellar Disease

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cerebellar Disease

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Pathways for genes affiliated with Cerebellar Disease

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Compounds for genes affiliated with Cerebellar Disease

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GO Terms for genes affiliated with Cerebellar Disease

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16Gene Ontology
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Cellular components related to Cerebellar Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear matrixGO:0163639.3ATXN7, SATB2

Molecular functions related to Cerebellar Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chromatin bindingGO:0036829.3ATXN7, SATB2

Products for genes affiliated with Cerebellar Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cerebellar Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet