MCID: CRB027
MIFTS: 35

Cerebellar Disease malady

Summaries for Cerebellar Disease

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Cerebellar Disease, also known as cerebellar deficiency syndrome, is related to movement disease and eye disease. An important gene associated with Cerebellar Disease is NDUFA4 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa). Affiliated tissues include cortex, eye and brain, and related mouse phenotype skeleton.

Aliases & Classifications for Cerebellar Disease

About this section
Sources:
8Disease Ontology, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH
See all sources

Aliases & Descriptions:

cerebellar disease 8
cerebellar deficiency syndrome 8
cerebellar dysfunction 44
cerebellar disorder 8
cerebellar diseases 60


External Ids:

Disease Ontology8 DOID:2786
MeSH34 D002526

Related Diseases for Cerebellar Disease

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Cerebellar Disease:



Diseases related to cerebellar disease

Clinical Features for Cerebellar Disease

About this section

Drugs & Therapeutics for Cerebellar Disease

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Cerebellar Disease

Drug clinical trials:

Search ClinicalTrials for Cerebellar Disease

Search NIH Clinical Center for Cerebellar Disease

Search CenterWatch for Cerebellar Disease

Genetic Tests for Cerebellar Disease

About this section

Anatomical Context for Cerebellar Disease

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Cerebellar Disease:

32
Cortex, Eye, Brain, Testes, Heart, Cerebellum, Thyroid, Thalamus, Ovary, Liver, Bone marrow, Bone, Tongue

Animal Models for Cerebellar Disease or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Cerebellar Disease:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.8ATXN7, PHF14, SATB2

Publications for Cerebellar Disease

About this section
Sources:
50PubMed
See all sources

Articles related to Cerebellar Disease:

(show top 50)    (show all 288)
idTitleAuthorsYear
1
Effects of task constraints on obstacle avoidance strategies in patients with cerebellar disease. (23022155)
2013
2
Diffusivity of cerebellar hemispheres enables discrimination of cerebellar or parkinsonian multiple system atrophy from progressive supranuclear palsy-Richardson syndrome and Parkinson disease. (23329659)
2013
3
Bilateral cerebellar epithelioid hemangioblastoma with possible ependymal differentiation in a patient with von Hippel-Lindau disease. (22364576)
2012
4
Pazopanib therapy for cerebellar hemangioblastomas in von Hippel-Lindau disease: case report. (22374327)
2012
5
Transient crossed cerebellar diaschisis due to cerebral hyperperfusion following surgical revascularization for moyamoya disease: case report. (22688075)
2012
6
Cerebellar metastatic papillary thyroid carcinoma in a pediatric patient with complex congenital heart disease. (23329771)
2012
7
Erdheim Chester disease presenting as slowly progressive cerebellar syndrome and asymptomatic widespread skeletal involvement. (21749566)
2011
8
Late onset Alexander's disease presenting as cerebellar ataxia associated with a novel mutation in the GFAP gene. (21165639)
2011
9
68Ga-DOTA-NOC PET/CT detects somatostatin receptors expression in von hippel-lindau cerebellar disease. (21157217)
2011
10
Spike removal through multiscale wavelet and entropy analysis of ocular motor noise: a case study in patients with cerebellar disease. (21262262)
2011
11
Assessing a dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) with 7T MR imaging. (20191074)
2010
12
Castleman's disease associated with a cerebellar chordoid meningioma and intestinal lymphangiectasia. (20567835)
2010
13
Layer specific changes of astroglial gap junctions in the rat cerebellar cortex by persistent Borna Disease Virus infection. (18538309)
2008
14
Fatal worsening of late-onset cerebellar ataxia with neuronal intranuclear inclusions due to superimposed meningeal Rosai-Dorfman disease. (18546340)
2008
15
Unilateral moyamoya disease associated with cerebellar arteriovenous malformation: one case report. (18706238)
2008
16
Apparent diffusion coefficient of the superior cerebellar peduncle differentiates progressive supranuclear palsy from Parkinson's disease. (18816803)
2008
17
Recurrent dural based cystic cerebellar haemangioblastoma in a patient with von Hippel-Lindau disease. (17357827)
2007
18
Apparent diffusion coefficient measurements of the middle cerebellar peduncle differentiate the Parkinson variant of MSA from Parkinson's disease and progressive supranuclear palsy. (16815875)
2006
19
Diagnostic approach to cerebellar disease in children. (16417854)
2005
20
Cerebellar ataxia and central nervous system whipple disease. (15824262)
2005
21
Cerebellar ataxia as the presenting manifestation of Lyme disease. (12075773)
2002
22
Cerebellar metastasis from papillary serous adenocarcinoma of the ovary mimicking MAcniA"re's disease. A case report. (11304872)
2001
23
Sporadic late onset paroxysmal cerebellar ataxia in four unrelated patients: a new disease? (11355155)
2001
24
Cerebellar ataxia associated with subclinical celiac disease responding to gluten-free diet. (10534283)
1999
25
Non-motor associative learning in patients with isolated degenerative cerebellar disease. (10050897)
1999
26
Cerebellar involvement in Pick's disease: affliction of mossy fibers, monodendritic brush cells, and dentate projection neurons. (10486184)
1999
27
Romberg sign: sensory dysfunction, not cerebellar disease. (9442758)
1998
28
Adaptation motor learning of arm movements in patients with cerebellar disease. (8778255)
1996
29
Paraneoplastic cerebellar degeneration: a rare presentation of Hodgkin's disease. (8536430)
1995
30
The gene for Machado-Joseph disease maps to the same 3-cM interval as the spinal cerebellar ataxia 3 gene on chromosome 14q. (9216989)
1994
31
Conditional associative learning is impaired in cerebellar disease in humans. (7917041)
1994
32
Histochemical study of mitochondrial enzymes in cerebellar cortex of macular mutant mouse, a model of Menkes kinky hair disease. (8009964)
1994
33
Recurrent dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease) presenting with subarachnoid haemorrhage. (1590970)
1992
34
Associated postural adjustments with body movement in normal subjects and patients with parkinsonism and cerebellar disease. (2263817)
1990
35
The prevalence of amyloid (A4) protein deposits within the cerebral and cerebellar cortex in Down's syndrome and Alzheimer's disease. (1698007)
1990
36
Paraneoplastic cerebellar degeneration due to Hodgkin's disease. (2660417)
1989
37
Menkes disease: a Golgi and electron microscopic study of the cerebellar cortex. (3390973)
1988
38
Epidemiological survey of an epidemic of congenital abnormalities with hydranencephaly-cerebellar hypoplasia syndrome of calves occurring in 1985/86 and seroepidemiological investigations on Chuzan virus, a putative causal agent of the disease, in Japan. (2838675)
1988
39
Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease. (2837558)
1988
40
Cerebellar involvement in murine sphingomyelinosis: a new model of Niemann-Pick disease. (3130465)
1988
41
Ocular signs of cerebellar disease. (7082205)
1982
42
Wesselsbron disease: a cause of congenital porencephaly and cerebellar hypoplasia in calves. (551364)
1979
43
Progressive cerebellar ataxia, spasticity, psychomotor retardation, and hexosaminidase deficiency in a 10-year-old child: juvenile Sandhoff disease. (559267)
1977
44
Gaze failure, drifting eye movements, and centripetal nystagmus in cerebellar disease. (603785)
1977
45
Fine structure of the cerebellar cortex in Menkes Kinky-hair disease. X-chromosome-linked copper malabsorption. (831687)
1977
46
Fine structural changes in the cerebellar cortex in kinky hair disease. (1028277)
1976
47
Cerebellar degeneration with Hodgkin disease. An immunological study. (962649)
1976
48
Pathogenesis of cerebellar hypoplasia produced by lymphocytic choriomeningitis virus infection of neonatal rats. 1. Evolution of disease following infection at 4 days of age. (4568304)
1973
49
Bovine viral diarrhea-mucosal disease implicated in a calf with cerebellar hypoplasia and ocular disease. A case report. (5103666)
1971
50
Familial cerebellar degeneration and atrophy; a sex-linked disease affecting Light Sussex pullets. (13641453)
1959

Genetic Variations for Cerebellar Disease

About this section

Expression for genes affiliated with Cerebellar Disease

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Cerebellar Disease

Search GEO for disease gene expression data for Cerebellar Disease.

Pathways for genes affiliated with Cerebellar Disease

About this section

Compounds for genes affiliated with Cerebellar Disease

About this section

GO Terms for genes affiliated with Cerebellar Disease

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Cerebellar Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear matrixGO:0163639.3ATXN7, SATB2

Molecular functions related to Cerebellar Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chromatin bindingGO:0036829.3ATXN7, SATB2

Products for genes affiliated with Cerebellar Disease

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cerebellar Disease

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet