MCID: CRB027
MIFTS: 35

Cerebellar Disease malady

Summaries for Cerebellar Disease

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32MalaCards
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MalaCards: Cerebellar Disease, also known as cerebellar deficiency syndrome, is related to movement disease and eye disease. An important gene associated with Cerebellar Disease is NDUFA4 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa). Affiliated tissues include cortex, eye and brain, and related mouse phenotype skeleton.

Aliases & Classifications for Cerebellar Disease

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8Disease Ontology, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

cerebellar disease 8
cerebellar deficiency syndrome 8
cerebellar dysfunction 44
cerebellar disorder 8
cerebellar diseases 60


External Ids:

Disease Ontology8 DOID:2786
MeSH34 D002526

Related Diseases for Cerebellar Disease

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Cerebellar Disease:



Diseases related to cerebellar disease

Clinical Features for Cerebellar Disease

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Drugs & Therapeutics for Cerebellar Disease

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Cerebellar Disease

Search NIH Clinical Center for Cerebellar Disease

Search CenterWatch for Cerebellar Disease

Genetic Tests for Cerebellar Disease

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Anatomical Context for Cerebellar Disease

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32MalaCards
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MalaCards organs/tissues related to Cerebellar Disease:

32
Cortex, Eye, Brain, Testes, Heart, Cerebellum, Thyroid, Thalamus, Ovary, Liver, Bone marrow, Bone, Tongue

Animal Models for Cerebellar Disease or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Cerebellar Disease:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.8ATXN7, PHF14, SATB2

Publications for Cerebellar Disease

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50PubMed
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Articles related to Cerebellar Disease:

(show top 50)    (show all 288)
idTitleAuthorsYear
1
Disturbed vestibular-neck interaction in cerebellar disease. (23081756)
2013
2
Brain stem and cerebellar atrophy in chronic progressive neuro-BehAset's disease. (23083524)
2013
3
Cerebellar ataxia with SYNE1 mutation accompanying motor neuron disease. (23325900)
2013
4
Cerebellar contribution to anger recognition deficits in Huntington's disease. (23709228)
2013
5
Cerebellar cognitive affective syndrome in Machado Joseph disease: core clinical features. (21975858)
2012
6
Bilateral sensorineural hearing loss and cerebellar ataxia in the case of late stage Lyme disease. (23306581)
2012
7
Cerebellar ataxia in patients with mitochondrial DNA disease: a molecular clinicopathological study. (22249460)
2012
8
Juvenile Huntington disease in an 18-month-old boy revealed by global developmental delay and reduced cerebellar volume. (21412977)
2011
9
Effects of cerebellar disease on sequences of rapid eye movements. (21385592)
2011
10
Coordinative and limb-specific control of bimanual movements in patients with Parkinson's disease and cerebellar degeneration. (20638443)
2010
11
Aphasia and neglect are uncommon in cerebellar disease: negative findings in a prospective study in acute cerebellar stroke. (20680538)
2010
12
Postoperative cerebellar mutism in adult patients with Lhermitte-Duclos disease. (20668902)
2010
13
Oculomotor findings mimicking a cerebellar disorder and postural control in severe Meniere's disease. (18501541)
2009
14
Case 144: Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease). (19332858)
2009
15
Clinical manifestation of focal cerebellar disease as related to the organization of neural pathways. (18439215)
2008
16
Cerebellar ataxia as a possible organ-specific autoimmune disease. (18546342)
2008
17
Redefining the disease locus of 16q22.1-linked autosomal dominant cerebellar ataxia. (17611710)
2007
18
Pediatric periodic alternating gaze deviation with midline cerebellar disease. (17280848)
2007
19
De novo appearance of cerebellar cavernous malformation in a patient with moyamoya disease: case report and review of the literature. (17574735)
2007
20
Von Hippel-Lindau disease germline mutations in Mexican patients with cerebellar hemangioblastoma. (16572651)
2006
21
Depth perception in cerebellar and basal ganglia disease. (16733701)
2006
22
Growth hormone response to arginine test distinguishes multiple system atrophy from Parkinson's disease and idiopathic late-onset cerebellar ataxia. (15807873)
2005
23
Treatment of recurrent cerebellar hemangioblastoma with external radiotherapy in a patient with von Hippel-Lindau disease: a case report and review of the literature. (15980980)
2005
24
A case of Salla disease with involvement of the cerebellar white matter. (12592494)
2003
25
Dissociation of habit-learning in Parkinson's and cerebellar disease. (11970808)
2002
26
Intact artificial grammar learning in patients with cerebellar degeneration and advanced Parkinson's disease. (11985834)
2002
27
Rhythmic tremor of the palate and other cranial limb muscles, with cerebellar ataxia: consider Whipple's disease. (11481720)
2001
28
Cerebellar degeneration in hereditary dentatorubral-pallidoluysian atrophy and Machado-Joseph disease. (10651027)
2000
29
Familial Creutzfeldt-Jakob disease with D178N-129M mutation of PRNP presenting as cerebellar ataxia without insomnia. (10787305)
2000
30
Celiac disease and idiopathic cerebellar ataxia. (10881272)
2000
31
Absence of a common functional denominator of visual disturbances in cerebellar disease. (10545398)
1999
32
Comparative analysis of gait in Parkinson's disease, cerebellar ataxia and subcortical arteriosclerotic encephalopathy. (10388800)
1999
33
Predicting disease progression in childhood cerebellar astrocytoma. (9840364)
1998
34
Machado-Joseph disease: cerebellar ataxia and autonomic dysfunction in a patient with the shortest known expanded allele (56 CAG repeat units) of the MJD1 gene. (9270607)
1997
35
The anatomy and physiology of cerebellar disease. (8421965)
1993
36
Paraneoplastic cerebellar degeneration. II. Clinical and immunologic findings in 21 patients with Hodgkin's disease. (1407576)
1992
37
Bovine viral diarrhea virus-induced cerebellar disease in a calf. (2276963)
1990
38
Microglia in cerebellar plaques in Alzheimer's disease. (2251906)
1990
39
A comparative immunocytochemical study of human cerebellar cortex in X-chromosome-linked copper malabsorption (Menkes' kinky hair disease) and granule cell type cerebellar degeneration. (2511498)
1989
40
Cerebellar disease without dementia and infection with the human immunodeficiency virus (HIV) (3341666)
1988
41
Hodgkin's disease and subacute cerebellar degeneration. A case report and review of the literature. (6739288)
1984
42
Combined acute necrotic myelopathy (ANM) and cerebellar degeneration associated with malignant disease. (6851302)
1983
43
Cerebellar degeneration with Hodgkin's disease: computed tomographic correlation and literature review. (7011281)
1981
44
Stumbler, a new mutant mouse with cerebellar disease. (7470926)
1981
45
Retinal and cerebellar changes in early fetal Sandhoff disease (GM2-gangliosidosis type 2). (7453274)
1980
46
Case report: cerebellar degeneration with Hodgkin's disease. (110407)
1979
47
Cerebellar degeneration and Hodgkin's disease. (454079)
1979
48
Hereditary spino-cerebellar degeneration and Ramsay-Hunt disease]. (4848865)
1974
49
Ocular dyskinesia in cerebellar disease. Evidence for the similarity of opsoclonus, ocular dysmetria and flutter-like oscillations. (4345909)
1972
50
Epidemiological observations on bovine viral diarrhea-mucosal disease virus-induced congenital cerebellar hypoplasia and ocular defects in calves. (4986633)
1970

Genetic Variations for Cerebellar Disease

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Expression for genes affiliated with Cerebellar Disease

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cerebellar Disease

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Pathways for genes affiliated with Cerebellar Disease

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Compounds for genes affiliated with Cerebellar Disease

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GO Terms for genes affiliated with Cerebellar Disease

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16Gene Ontology
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Cellular components related to Cerebellar Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear matrixGO:0163639.3ATXN7, SATB2

Molecular functions related to Cerebellar Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chromatin bindingGO:0036829.3ATXN7, SATB2

Products for genes affiliated with Cerebellar Disease

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Sources for Cerebellar Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet