Aliases & Classifications for Cerebral Aneurysms

MalaCards integrated aliases for Cerebral Aneurysms:

Name: Cerebral Aneurysms 51
Cerebral Aneurysm 29 52 69
Cerebral Arterial Aneurysm 69

Summaries for Cerebral Aneurysms

NINDS : 51 A cerebral aneurysm is a weak or thin spot on a blood vessel in the brain that balloons out and fills with blood.  An aneurysm can press on a nerve or surrounding tissue, and also leak or burst, which lets blood spill into surrounding tissues (called a hemorrhage). Cerebral aneurysms can occur at any age, although they are more common in adults than in children and are slightly more common in women than in men.  The signs and symptoms of an unruptured cerebral aneurysm will partly depend on its size and rate of growth. For example, a small, unchanging aneurysm will generally produce no symptoms, whereas a larger aneurysm that is steadily growing may produce symptoms such as headache, numbness, loss of feeling in the face or problems with the eyes. Immediately after an aneurysm ruptures, an individual may experience such symptoms as a sudden and unusually severe headache, nausea, vision impairment, vomiting, and loss of consciousness.

MalaCards based summary : Cerebral Aneurysms, also known as cerebral aneurysm, is related to aneurysm and intracranial berry aneurysm. An important gene associated with Cerebral Aneurysms is PKD1 (Polycystin 1, Transient Receptor Potential Channel Interacting), and among its related pathways/superpathways are Degradation of the extracellular matrix and Lung fibrosis. The drugs Propofol and Sevoflurane have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and heart, and related phenotype is neoplasm.

Related Diseases for Cerebral Aneurysms

Diseases related to Cerebral Aneurysms via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
id Related Disease Score Top Affiliating Genes
1 aneurysm 11.6
2 intracranial berry aneurysm 11.4
3 intracranial aneurysm 11.4
4 cerebritis 10.9
5 loeys-dietz syndrome 4 10.8
6 berry aneurysm, cirrhosis, pulmonary emphysema, and cerebral calcification 10.8
7 strongyloidiasis 10.2 ELN PKD1
8 focal dystonia 10.2 CCL2 CST3
9 calcinosis 10.0 CCL2 CST3
10 familial cerebral saccular aneurysm 10.0
11 exocrine pancreatic insufficiency 10.0 CST3 PKD1
12 papular elastorrhexis 10.0 ELANE ELN
13 alcoholic pancreatitis 9.9 ELANE ELN
14 neonatal period electroclinical syndrome 9.9 CCL2 ELANE
15 tetanus 9.9 ELANE ELN
16 arteriovenous malformation 9.9
17 anal fistula 9.9 ELANE ELN
18 bardet-biedl syndrome 8 9.9 ELANE ELN
19 ragweed sensitivity 9.9 CCL2 ELANE
20 alcohol abuse 9.9 ELANE ELN
21 middle lobe syndrome 9.9 CCL2 ELANE
22 pulmonary sarcoidosis 9.9 ELANE ELN
23 myelophthisic anemia 9.9 CCL2 ELN
24 acute chest syndrome 9.9 CCL2 ELANE
25 vulva fibroepithelial polyp 9.8 CCL2 ELANE
26 diamond-blackfan anemia 1 9.8 CCL2 ELANE
27 hydrocephalus 9.8
28 thrombosis 9.8
29 headache 9.8
30 lymphoplasmacytic lymphoma 9.8 ELANE PKD1
31 takayasu arteritis 9.8
32 endotheliitis 9.8
33 chickenpox 9.7 CCL2 ELANE
34 pericarditis 9.7 CCL2 CST3 ELN
35 cervix uteri carcinoma in situ 9.7 CST3 PKD1
36 loeys-dietz syndrome 9.7
37 ischemia 9.7
38 carotid artery occlusion 9.7
39 fibromuscular dysplasia 9.7
40 thunderclap headache 9.7
41 cryoglobulinemia 9.7 CTSB ELANE
42 macroglobulinemia, waldenstrom 1 9.6 ELANE ELN
43 adenoid squamous cell carcinoma 9.6 CCL2 ELANE
44 liver disease 9.6
45 polycystic liver disease 9.6
46 metal allergy 9.6
47 aseptic meningitis 9.6
48 osteogenesis imperfecta 9.6
49 dermatitis 9.6
50 choriocarcinoma 9.6

Graphical network of the top 20 diseases related to Cerebral Aneurysms:



Diseases related to Cerebral Aneurysms

Symptoms & Phenotypes for Cerebral Aneurysms

MGI Mouse Phenotypes related to Cerebral Aneurysms:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 CST3 CTSB ELANE PKD1

Drugs & Therapeutics for Cerebral Aneurysms

Drugs for Cerebral Aneurysms (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 195)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 2078-54-8 4943
2
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
3
Benzocaine Approved Phase 4,Phase 1,Phase 2,Early Phase 1 1994-09-7, 94-09-7 2337
4
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 76631-46-4, 113775-47-6 68602 5311068 56032
5
Desflurane Approved Phase 4 57041-67-5 42113
6
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
7
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
8
Morphine Approved, Investigational Phase 4 57-27-2 5288826
9
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 1 50-78-2 2244
10 Piracetam Approved Phase 4 7491-74-9
11
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
12 tannic acid Approved, Nutraceutical Phase 4,Phase 1,Phase 2,Early Phase 1
13
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
14 Etiracetam Investigational Phase 4 33996-58-6
15 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
16 Anesthetics, General Phase 4,Phase 3,Phase 2
17 Anesthetics, Inhalation Phase 4,Phase 3,Phase 2
18 Central Nervous System Depressants Phase 4,Phase 3,Phase 1,Phase 2
19 Platelet Aggregation Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
20 Analgesics Phase 4,Phase 3,Phase 1,Phase 2
21 Neurotransmitter Agents Phase 4,Phase 3,Phase 1,Phase 2
22 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2
23 Anticonvulsants Phase 4
24 Neuroprotective Agents Phase 4,Phase 2,Phase 3
25 Nootropic Agents Phase 4,Phase 2,Phase 3
26 Protective Agents Phase 4,Phase 2,Phase 3
27 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Anesthetics, Intravenous Phase 4,Phase 3,Phase 2
29 Hypnotics and Sedatives Phase 4,Phase 3,Phase 1,Phase 2
30 Adrenergic Agents Phase 4,Phase 3,Phase 1,Phase 2
31 Adrenergic Agonists Phase 4,Phase 3,Phase 1,Phase 2
32 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 3,Phase 1,Phase 2
33 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 1,Phase 2
34 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 1,Phase 2
35 Adjuvants, Anesthesia Phase 4,Phase 2
36 Analgesics, Opioid Phase 4
37 Narcotics Phase 4
38 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1
39 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 1
40 Antipyretics Phase 4,Phase 3,Phase 1
41 Antirheumatic Agents Phase 4,Phase 3,Phase 1
42 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 1
43 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
44 Purinergic P2 Receptor Antagonists Phase 4,Phase 3
45 Purinergic P2Y Receptor Antagonists Phase 4,Phase 3
46 Hematinics Phase 4,Phase 1
47 Epoetin alfa Phase 4 113427-24-0
48
Esmolol Approved Phase 3 103598-03-4, 81147-92-4 59768
49
Simvastatin Approved Phase 3 79902-63-9 54454
50
Ticagrelor Approved Phase 3 274693-27-5 9871419

Interventional clinical trials:

(show top 50) (show all 247)

id Name Status NCT ID Phase Drugs
1 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
2 HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study Unknown status NCT01516658 Phase 4
3 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
4 TRAIL: Treatment of Intracranial Aneurysms With LVIS® System Completed NCT02921711 Phase 4
5 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function Completed NCT02691416 Phase 4 propofol postconditioning;sevoflurane
6 The Registry to Study Safety and Performance of the CORDIS Vascular Reconstruction Device and Delivery System Completed NCT00486226 Phase 4
7 PRET: Patients Prone to Recurrence After Endovascular Treatment Completed NCT00626912 Phase 4
8 Aneurysm Wall Histology Registry Completed NCT01444664 Phase 4
9 MAPS Trial: Matrix And Platinum Science Completed NCT00396981 Phase 4
10 A Better Choice for Patients Undergoing Endovascular Coil Embolization Completed NCT01722409 Phase 4 sevoflurane and 0.5 μg/kg dexmedetomidine;sevoflurane and 1 μg/kg dexmedetomidine
11 Comparison of Neuroprotection by Propofol and Desflurane for POCD Following Subarachnoid Hemorrhage Surgery Completed NCT02987218 Phase 4 Propofol;Desflurane
12 The Pharmacokinetics of Opioids and Sedative/Hypnotics During Selective Cerebral Perfusion Completed NCT00494598 Phase 4 Sufentanil
13 Effects of a Surgery-induced Peripheral Inflammatory Response on the Blood Brain Barrier Completed NCT00878371 Phase 4 morphine
14 TARGET Intracranial Aneurysm Coiling Registry Recruiting NCT01748903 Phase 4
15 Flow Diversion in Intracranial Aneurysm Treatment Recruiting NCT01349582 Phase 4
16 Stenting in the Treatment of Aneurysm Trial Recruiting NCT01340612 Phase 4
17 Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil Recruiting NCT02729740 Phase 4
18 Seizure Prophylaxis in Aneurysm Repair Recruiting NCT01801072 Phase 4 Levetiracetam
19 LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling Therapy Recruiting NCT01762137 Phase 4
20 Study of the Penumbra Coil 400 System to Treat Aneurysm Active, not recruiting NCT01465841 Phase 4
21 Study of Antiplatelet Therapy for Intracranial Aneurysm Stent-assisted Coiling Not yet recruiting NCT02224131 Phase 4 Aspirin and clopidogrel;Aspirin and clopidogrel
22 HydroCoil Cerebral Aneurysm Treatment Trial Terminated NCT01195129 Phase 4
23 Seizure Prophylaxis in Aneurysm Repair Terminated NCT01974700 Phase 4 Levetiracetam
24 Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
25 Hydrogel Balloon Assisted Intracranial Aneurysm Coiling Registry Withdrawn NCT02037932 Phase 4
26 Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety and Efficacy of Cerebrolysin™ in Patients With Aneurysmal Subarachnoid Hemorrhage Unknown status NCT01787123 Phase 2, Phase 3 Intravenous Cerebrolysin
27 The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure Unknown status NCT00110201 Phase 3 Nesiritide
28 Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device Completed NCT01541254 Phase 2, Phase 3
29 Complete Occlusion of Coilable Aneurysms Completed NCT00777907 Phase 3
30 Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support) Completed NCT01793792 Phase 3
31 Esmolol Infusion in Patients Undergoing Craniotomy Completed NCT02455440 Phase 3 Esmolol;Placebo;Propofol and sevoflurane
32 Hypothermia During Intracranial Aneurysm Surgery Trial Completed NCT00029133 Phase 3
33 Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical Trial Completed NCT00731627 Phase 3 placebo;simvastatin
34 Framing Eighteen Coils in Cerebral Aneurysms Trial Recruiting NCT01655784 Phase 3
35 Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral Aneurysm Recruiting NCT02675205 Phase 3 Clopidogrel;Ticagrelor;aspirin
36 Acetylsalicylic Acid Plus Intensive Blood Pressure Treatment in Patients With Unruptured Intracranial Aneurysms Recruiting NCT03063541 Phase 3 Acetylsalicylic acid
37 Esmolol Versus Dexmedetomidine During Intracranial Procedures Recruiting NCT02563288 Phase 3 Esmolol;Dexmedetomidine
38 Hypovitaminosis D in Neurocritical Patients Recruiting NCT02881957 Phase 2, Phase 3 Cholecalciferol
39 The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms Active, not recruiting NCT01636453 Phase 3
40 Pivotal Study of the FRED Stent System in the Treatment of Intracranial Aneurysms Active, not recruiting NCT01801007 Phase 3
41 Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. Not yet recruiting NCT03187405 Phase 3 EVD + IVF with Alteplase
42 Clevidipine for Vasospasm After Subarachnoid Hemorrhage (SAH) Unknown status NCT02011321 Phase 2 clevidipine
43 Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid Hemorrhage Unknown status NCT01098890 Phase 2 Tissue Plasminogen Activator;Placebo
44 Lycopene Following Aneurysmal Subarachnoid Haemorrhage Unknown status NCT00905931 Phase 2 Lycopene;placebo
45 Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm Completed NCT00873015 Phase 2 Sodium nitrite;Saline
46 Safety and Tolerability Study of EG-1962 in Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
47 Evaluating Neuroprotection in Aneurysm Coiling Therapy Completed NCT00728182 Phase 2 NA-1;Placebo
48 Dexmedetomidine and Subarachnoid Haemorrhage Completed NCT01664520 Phase 1, Phase 2 Dexmedetomidine infusion
49 Evaluation of the Efficacy and Safety of Clazosentan in Reversing Cerebral Vasospasm in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage Completed NCT02560532 Phase 2 Clazosentan
50 Safety Study of Dantrolene to Treat Cerebral Vasospasm After Subarachnoid Hemorrhage Completed NCT00964548 Phase 1, Phase 2 Dantrolene;Dantrolene

Search NIH Clinical Center for Cerebral Aneurysms

Genetic Tests for Cerebral Aneurysms

Genetic tests related to Cerebral Aneurysms:

id Genetic test Affiliating Genes
1 Cerebral Aneurysm 29

Anatomical Context for Cerebral Aneurysms

MalaCards organs/tissues related to Cerebral Aneurysms:

39
Brain, Eye, Heart, Pituitary, Whole Blood, Bone, Spinal Cord

Publications for Cerebral Aneurysms

Articles related to Cerebral Aneurysms:

(show top 50) (show all 699)
id Title Authors Year
1
Comparison of the Prevalence of Ruptured and Unruptured Cerebral Aneurysms in a Poor Urban Minority Population. ( 28623116 )
2017
2
Size is the Most Important Predictor of Aneurysm Rupture Among Multiple Cerebral Aneurysms: Post Hoc Subgroup Analysis of Unruptured Cerebral Aneurysm Study Japan. ( 28637201 )
2017
3
Circumferential Wall Enhancement on Magnetic Resonance Imaging is Useful to Identify Rupture Site in Patients with Multiple Cerebral Aneurysms. ( 28586440 )
2017
4
Intraprocedural Rupture of Unruptured Cerebral Aneurysms During Coil Embolization: A Single-Center Experience. ( 28583450 )
2017
5
The Use of Ultrabrief Left Unilateral Electroconvulsive Therapy in a Patient With Cerebral Aneurysms and Right-Sided Encephalomalacia and Stroke: A Case Report. ( 28767530 )
2017
6
Monolateral pterional keyhole approaches to bilateral cerebral aneurysms: Anatomy and clinical application. ( 28927909 )
2017
7
Macrophage Imaging of Cerebral Aneurysms with Ferumoxytol: an Exploratory Study in an Animal Model and in Patients. ( 28774792 )
2017
8
Small Cerebral Aneurysms: Can We Identify Patients at Risk for Rupture? ( 28586919 )
2017
9
The effectiveness of Penumbra 400 micro-coils in the embolization of large cerebral aneurysms. ( 28577823 )
2017
10
Occlusion status on magnetic resonance angiography is associated with risk of delayed ischemic events in cerebral aneurysms treated with stent-assisted coiling. ( 28826708 )
2017
11
Cerebral Aneurysm Size and Distal Intracranial Hemodynamics: An Assessment of Flow and Pulsatility Index Using Quantitative Magnetic Resonance Angiography. ( 28945889 )
2017
12
Three-year experience with interventional neuroradiology for management of cerebral aneurysms at a single Australian centre. ( 28726260 )
2017
13
Update on flow diverters for the endovascular management of cerebral aneurysms. ( 28565980 )
2017
14
Clinical evaluation of time-of-flight MR angiography with sparse undersampling and iterative reconstruction for cerebral aneurysms. ( 28796397 )
2017
15
Introduction. The treatment of cerebral aneurysms: flow diversion and beyond. ( 28565982 )
2017
16
Flow diversion of tandem cerebral aneurysms: a multi-institutional retrospective study. ( 28565979 )
2017
17
Complications associated with the use of flow-diverting devices for cerebral aneurysms: a systematic review and meta-analysis. ( 28565981 )
2017
18
Deep neural network-based computer-assisted detection of cerebral aneurysms in MR angiography. ( 28836310 )
2017
19
Postprocedural, midterm, and long-term results of cerebral aneurysms treated with flow-diverter devices: 7-year experience at a single center. ( 28565988 )
2017
20
Transradial approach to treating endovascular cerebral aneurysms: Case series and technical note. ( 28584676 )
2017
21
Balloon-assisted coil embolization and large stent delivery for cerebral aneurysms with a new generation of dual lumen balloons (Copernic 2L). ( 28754807 )
2017
22
Successful Treatment With Electroconvulsive Therapy of a Patient With Bipolar Disorder and a 7-mm Cerebral Aneurysm. ( 28072662 )
2017
23
Is there A Genetic Correlation between Multiple Sclerosis and Cerebral Aneurysms? ( 27090970 )
2016
24
White-collar sign as a predictor of outcome after endovascular treatment for cerebral aneurysms. ( 27177179 )
2016
25
Regarding "Computer-Assisted Detection of Cerebral Aneurysms in MR Angiography in a Routine Image-Reading Environment: Effects on Diagnosis by Radiologists". ( 27561835 )
2016
26
Clinical and Angiographic Outcomes of Endovascular Treatment for Ruptured Posterior Circulation Cerebral Aneurysms. ( 27400096 )
2016
27
Aneurysm outflow angle at MRA as discriminant for accurate diagnosis and differentiation between small sidewall cerebral aneurysms and infundibula. ( 27260972 )
2016
28
Infective Endocarditis due to Abiotrophia defectiva and Granulicatella sp. complicated by Infectious Intracranial Cerebral Aneurysms: A Report of 3 Cases and Review of the Literature. ( 27046228 )
2016
29
Endovascular treatment of cerebral aneurysms using the Woven EndoBridge technique in a single center: preliminary results. ( 27081907 )
2016
30
Extracranial to intracranial bypass for the treatment of cerebral aneurysms in the pediatric population. ( 27430415 )
2016
31
Clinical outcome after surgical clipping or endovascular coiling for cerebral aneurysms: a pragmatic meta-analysis of randomized and non-randomized trials with short- and long-term follow-up. ( 27053705 )
2016
32
Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats. ( 27349749 )
2016
33
Stent-assisted coiling in ruptured cerebral aneurysms: multi-center experience in acute phase. ( 27631680 )
2016
34
Prevalence and Characteristics of Unruptured Cerebral Aneurysms in Ischemic Stroke Patients. ( 27488981 )
2016
35
Biology of Saccular Cerebral Aneurysms: A Review of Current Understanding and Future Directions. ( 27504449 )
2016
36
Preemptive Medicine for Cerebral Aneurysms. ( 27053328 )
2016
37
Determining the Presence of Thin-Walled Regions at High-Pressure Areas in Unruptured Cerebral Aneurysms by Using Computational Fluid Dynamics. ( 27028475 )
2016
38
Experimental Induction of Cerebral Aneurysms by Developmental Low Copper Diet. ( 27030743 )
2016
39
Sexual Activity as a Risk Factor for the Spontaneous Rupture of Cerebral Aneurysms. ( 27043460 )
2016
40
The role of estrogen on the pathology of cerebral aneurysms. ( 27177293 )
2016
41
Geographic Differences in Endovascular Treatment and Retreatment of Cerebral Aneurysms. ( 27390314 )
2016
42
Flow Diversion for Cerebral Aneurysms: A Promising Therapy Needs Full Evaluation. ( 27083132 )
2016
43
Diagnostic limitations in the treatment of cerebral aneurysms. ( 27075386 )
2016
44
A computational model based on fibrin accumulation for the prediction of stasis thrombosis following flow-diverting treatment in cerebral aneurysms. ( 27106753 )
2016
45
Risk of rupture of unruptured cerebral aneurysms in elderly patients. ( 27164645 )
2016
46
Molecular Imaging in Neurovascular Diseases: The Use of Ferumoxytol to Assess Cerebral Aneurysms and Arteriovenous Malformations. ( 27049242 )
2016
47
Cerebral Aneurysms: Accuracy of 320-Detector Row Nonsubtracted and Subtracted Volumetric CT Angiography for Diagnosis. ( 27643778 )
2016
48
Wall shear stress at the initiation site of cerebral aneurysms. ( 27440126 )
2016
49
Bypass Surgeries in the Treatment of Cerebral Aneurysms. ( 27637629 )
2016
50
Comparison of clipping and coiling in elderly patients with unruptured cerebral aneurysms. ( 27203150 )
2016

Variations for Cerebral Aneurysms

ClinVar genetic disease variations for Cerebral Aneurysms:

6
id Gene Variation Type Significance SNP ID Assembly Location
1 PKD1 NM_000296.3(PKD1): c.2079dupG (p.Pro694Alafs) duplication Pathogenic rs1057518923 GRCh37 Chromosome 16, 2165397: 2165397

Expression for Cerebral Aneurysms

Search GEO for disease gene expression data for Cerebral Aneurysms.

Pathways for Cerebral Aneurysms

Pathways related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.09 CTSB ELANE ELN
2 10.96 CCL2 ELN
3 10.55 ELANE ELN
4 10.04 CST3 CTSB

GO Terms for Cerebral Aneurysms

Cellular components related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 perinuclear region of cytoplasm GO:0048471 9.33 CCL2 CST3 CTSB
2 ficolin-1-rich granule lumen GO:1904813 9.26 CST3 CTSB
3 extracellular space GO:0005615 9.26 CCL2 CST3 CTSB ELANE
4 extracellular region GO:0005576 9.02 CCL2 CST3 CTSB ELANE ELN

Biological processes related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 animal organ morphogenesis GO:0009887 9.37 CCL2 ELN
2 neutrophil degranulation GO:0043312 9.33 CST3 CTSB ELANE
3 cellular calcium ion homeostasis GO:0006874 9.32 CCL2 ELANE
4 extracellular matrix disassembly GO:0022617 9.26 ELANE ELN
5 JAK-STAT cascade GO:0007259 8.96 CCL2 PKD1
6 leukocyte migration involved in inflammatory response GO:0002523 8.62 CCL2 ELANE

Molecular functions related to Cerebral Aneurysms according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.62 CST3 ELANE

Sources for Cerebral Aneurysms

3 CDC
7 CNVD
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10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
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31 HMDB
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33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
37 KEGG
38 LifeMap
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42 MeSH
43 MESH via Orphanet
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65 SNOMED-CT via HPO
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