MCID: CRB031
MIFTS: 27

Cerebral Arterial Disease

Categories: Cardiovascular diseases

Aliases & Classifications for Cerebral Arterial Disease

MalaCards integrated aliases for Cerebral Arterial Disease:

Name: Cerebral Arterial Disease 12 14
Cerebral Arterial Diseases 41 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3527
MeSH 41 D002539
UMLS 69 C0007774

Summaries for Cerebral Arterial Disease

MalaCards based summary : Cerebral Arterial Disease, also known as cerebral arterial diseases, is related to moyamoya disease 1 and aneurysm. An important gene associated with Cerebral Arterial Disease is RNF213 (Ring Finger Protein 213). The drugs Abciximab and Piracetam have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and endothelial.

Related Diseases for Cerebral Arterial Disease

Graphical network of the top 20 diseases related to Cerebral Arterial Disease:



Diseases related to Cerebral Arterial Disease

Symptoms & Phenotypes for Cerebral Arterial Disease

Drugs & Therapeutics for Cerebral Arterial Disease

Drugs for Cerebral Arterial Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 77)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Abciximab Approved Phase 4 143653-53-6
2 Piracetam Approved, Investigational Phase 4 7491-74-9
3 Antimetabolites Phase 4
4 Hypolipidemic Agents Phase 4
5 Lipid Regulating Agents Phase 4
6 Anticoagulants Phase 4,Phase 2
7 Fibrinolytic Agents Phase 4,Phase 3,Phase 2
8 Platelet Aggregation Inhibitors Phase 4,Phase 3
9 Tissue Plasminogen Activator Phase 4,Phase 3,Phase 2
10 Plasminogen Phase 4,Phase 2
11 Pharmaceutical Solutions Phase 4,Phase 2
12 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
13 Anticholesteremic Agents Phase 4
14 Calcium, Dietary Phase 4
15 Rosuvastatin Calcium Phase 4 147098-20-2
16 Antibodies Phase 4
17 Antibodies, Monoclonal Phase 4
18 Immunoglobulin Fab Fragments Phase 4
19 Immunoglobulins Phase 4
20
Aspirin Approved, Vet_approved Phase 3 50-78-2 2244
21
Clopidogrel Approved Phase 3 120202-66-6, 113665-84-2 60606
22
Ticlopidine Approved Phase 3 55142-85-3 5472
23
Esmolol Approved Phase 3 81147-92-4, 103598-03-4 59768
24
Propofol Approved, Investigational, Vet_approved Phase 3 2078-54-8 4943
25
Sevoflurane Approved, Vet_approved Phase 3 28523-86-6 5206
26
Xylometazoline Approved, Investigational Phase 3 526-36-3 5709
27
Mannitol Approved, Investigational Phase 3 69-65-8 6251 453
28 Analgesics Phase 3
29 Analgesics, Non-Narcotic Phase 3
30 Anti-Inflammatory Agents Phase 3
31 Anti-Inflammatory Agents, Non-Steroidal Phase 3
32 Antipyretics Phase 3
33 Antirheumatic Agents Phase 3
34 Cyclooxygenase Inhibitors Phase 3
35 Cytochrome P-450 Enzyme Inhibitors Phase 3
36 Neurotransmitter Agents Phase 3,Phase 2
37 Peripheral Nervous System Agents Phase 3
38 Purinergic P2 Receptor Antagonists Phase 3
39 Purinergic P2Y Receptor Antagonists Phase 3
40 Adrenergic Agents Phase 3
41 Adrenergic Antagonists Phase 3
42 Adrenergic beta-1 Receptor Antagonists Phase 3
43 Adrenergic beta-Antagonists Phase 3
44 Anesthetics Phase 3,Phase 1,Phase 2
45 Anesthetics, General Phase 3
46 Anesthetics, Inhalation Phase 3
47 Anesthetics, Intravenous Phase 3
48 Central Nervous System Depressants Phase 3
49 Hypnotics and Sedatives Phase 3
50 Epoetin alfa Phase 2, Phase 3,Phase 1 113427-24-0

Interventional clinical trials:

(show top 50) (show all 63)

# Name Status NCT ID Phase Drugs
1 Effect of Rosuvastatin on Prognosis of Clinical Response in Acute Ischemic Stroke Patients(REPAIRS) Not yet recruiting NCT02484027 Phase 4 Rosuvastatin
2 Thrombectomy Under Reopro Versus Alteplase to Treat Stoke Terminated NCT02016547 Phase 4 alteplase 0.9mg/kg (10% by IV bolus following by 90% by 1 hour IV drip)
3 A Study to Evaluate the Efficacy and Safety of Piracetam on Aphasia After Acute Ischemic Cerebral Artery Stroke Terminated NCT01883011 Phase 4 Piracetam
4 The Carotid and Middle Cerebral Artery Occlusion Surgery Study Unknown status NCT01758614 Phase 3 Aspirin;Clopidogrel
5 Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion Unknown status NCT00336596 Phase 3
6 Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF) Completed NCT01012674 Phase 3 Dotarem
7 Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF) Completed NCT01010932 Phase 3 Dotarem
8 Esmolol Infusion in Patients Undergoing Craniotomy Completed NCT02455440 Phase 3 Esmolol;Placebo;Propofol and sevoflurane
9 Multicenter Efficacy Study of Recombinant Human Erythropoietin in Acute Ischemic Stroke Completed NCT00604630 Phase 2, Phase 3 recombinant human erythropoietin alfa;0.9% NaCl
10 The Adult Hemorrhagic Moyamoya Surgery Study Active, not recruiting NCT02319980 Phase 3
11 Hemicraniectomy for Malignant Middle Cerebral Artery Infarction (HeMMI): A Single Center Randomized Controlled Clinical Trial Terminated NCT02002234 Phase 3
12 Decompressive Craniectomy In Malignant Middle Cerebral Artery Infarcts Terminated NCT00190203 Phase 3
13 Autologous Bone Marrow Stromal Cell and Endothelial Progenitor Cell Transplantation in Ischemic Stroke Unknown status NCT01468064 Phase 1, Phase 2
14 Intravenous Autologous Mesenchymal Stem Cells Transplantation to Treat Middle Cerebral Artery Infarct Unknown status NCT01461720 Phase 2
15 Safety Study of Dabigatran in CADASIL Unknown status NCT01361763 Phase 2 Dabigatran;Antiplatelets
16 Study Evaluating the Safety,Tolerability and Efficacy of PF-04360365 in Adults With Probable Cerebral Amyloid Angiopathy Completed NCT01821118 Phase 2
17 Multiple Burrhole Therapy With Erythropoietin for Unstable Moyamoya Completed NCT03162588 Phase 1, Phase 2 erythropoietin
18 Cerebrilâ„¢ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy Completed NCT00056238 Phase 2 NC-758 (Anti amyloidotic [Aß] agent)
19 Stem Cell Therapy For Acute Ischemic Stroke Patients Completed NCT02425670 Phase 2
20 Efficacy Study of CD34 Stem Cell in Chronic Stroke Patients Completed NCT00950521 Phase 2 convention therapy
21 Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion Completed NCT00777140 Phase 2 Deferoxamine
22 Autologous Bone Marrow Stem Cells in Middle Cerebral Artery Acute Stroke Treatment. Completed NCT00761982 Phase 1, Phase 2
23 Autologous Bone Marrow Stem Cells in Ischemic Stroke. Completed NCT00535197 Phase 1, Phase 2
24 The Efficacy, Safety, And Tolerability Of Donepezil HCl (E2020) In Patients With CADASIL Who Have Cognitive Impairment Completed NCT00103948 Phase 2 Aricept
25 Superiority of Rt-PA + Tenecteplase in Comparison With Rt-PA Only in Proximal Middle Cerebral Artery Occlusion Not yet recruiting NCT02338466 Phase 2 rt-PA;tenecteplase
26 Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke Terminated NCT01310114 Phase 2 Placebo
27 The Efficacy and Safety of MK0724 IV for Improvement of Neurological Damage and Recovery From Middle Cerebral Artery Ischemic Stroke (0724-018) Terminated NCT00401310 Phase 2 Comparator: Placebo;Comparator: MK0724
28 Study of Purified Umbilical Cord Blood CD34+ Stem Cell on Chronic Ischemic Stroke Unknown status NCT01438593 Phase 1
29 Implantation of Olfactory Ensheathing Cells (OECs) Unknown status NCT01327768 Phase 1
30 Intraarterial Stem Cells in Subacute Ischemic Stroke Completed NCT03080571 Phase 1
31 Study of Autologous Stem Cell Transplantation for Patients With Ischemic Stroke Completed NCT00473057 Phase 1
32 Characteristics and Outcomes of Childhood Moyamoya in the UK Unknown status NCT02434302
33 Methods of Etiological Diagnosis of Cerebral Amyloid Angiopathy Unknown status NCT02361411
34 Subclavian Vein catheterization_Seldinger Vs Modified Seldinger Unknown status NCT02090010
35 Imaging Study of Neurovascular Coupling in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Unknown status NCT02071784
36 The Role of Cerebral Hemodynamics in Moyamoya Disease Unknown status NCT00629915
37 Normal Values of Brain Oxygenation Completed NCT00512447
38 Longitudinal Study of Neurologic, Cognitive, and Radiologic Outcomes of PHACE Syndrome Completed NCT01018082
39 Intracranial Pressure After Decompressive Craniectomy Completed NCT03364634
40 The Silent Cortical Infarcts in the Cerebral Amyloid Angiopathy: Is There a Link With Subarachnoid Hemorrhage? Completed NCT02837354
41 A Comparison Between Two Techniques for Performing Decompressive Craniectomy Completed NCT02594137
42 Impact of tDCS on Cerebral Autoregulation Completed NCT01865604
43 Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients Completed NCT01419275 Xenon contrast agent
44 Research Study on Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Completed NCT01114815
45 Impact of Cranioplasty On Cerebral Perfusion Completed NCT01113645
46 Gait Training for Persons With Stroke Completed NCT00612300 Early Phase 1
47 Prospective Observation for Serial Changes of Acute Intracranial Artery Dissection Using High Resolution MRI Recruiting NCT02914288
48 EEG Monitoring in Children With Moyamoya Disease Recruiting NCT03173014
49 Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease Recruiting NCT02982135
50 Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial Recruiting NCT03098732

Search NIH Clinical Center for Cerebral Arterial Disease

Cochrane evidence based reviews: cerebral arterial diseases

Genetic Tests for Cerebral Arterial Disease

Anatomical Context for Cerebral Arterial Disease

MalaCards organs/tissues related to Cerebral Arterial Disease:

38
Bone Marrow, Bone, Endothelial, Brain, Skin

Publications for Cerebral Arterial Disease

Articles related to Cerebral Arterial Disease:

(show all 15)
# Title Authors Year
1
Nonatheroscleotic Isolated Middle Cerebral Artery Disease May Be Early Manifestation of Moyamoya Disease. ( 27507861 )
2016
2
Frequency and Risk Factors for Cerebral Arterial Disease in a HIV/AIDS Neuroimaging Cohort. ( 26751784 )
2016
3
Progressive Cortical Neuronal Damage and Chronic Hemodynamic Impairment in Atherosclerotic Major Cerebral Artery Disease. ( 27217506 )
2016
4
Misery Perfusion, Blood Pressure Control, and 5-Year Stroke Risk in Symptomatic Major Cerebral Artery Disease. ( 25395413 )
2014
5
Associations of ankle-brachial index (ABI) with cerebral arterial disease and vascular events following ischemic stroke. ( 22652527 )
2012
6
Assessment of pial branches using 7-tesla MRI in cerebral arterial disease. ( 20185908 )
2010
7
Risk factors for stroke in different levels of cerebral arterial disease. ( 10529541 )
1999
8
High prevalence of unsuspected abdominal aortic aneurysm in patients with confirmed symptomatic peripheral or cerebral arterial disease. ( 8518892 )
1993
9
Occlusive cerebral arterial disease. ( 6839323 )
1983
10
Intracranial bypass surgery for cerebral arterial disease and the responsibility of the practicing physician. ( 462524 )
1979
11
Effect of ethyl apovincaminate on the cerebral circulation. Studies in patients with obliterative cerebral arterial disease. ( 1037221 )
1976
12
Cerebral arterial disease in children. An angiographic study of 40 cases. ( 5579392 )
1971
13
The significance of naturally occurring coronary and cerebral arterial disease in animals. ( 5253796 )
1968
14
Cerebral arterial disease. ( 14417991 )
1959
15
Cerebral arterial disease. ( 14430850 )
1959

Variations for Cerebral Arterial Disease

Expression for Cerebral Arterial Disease

Search GEO for disease gene expression data for Cerebral Arterial Disease.

Pathways for Cerebral Arterial Disease

GO Terms for Cerebral Arterial Disease

Sources for Cerebral Arterial Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....