MCID: CRB031
MIFTS: 27

Cerebral Arterial Disease malady

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Cerebral Arterial Disease

Aliases & Descriptions for Cerebral Arterial Disease:

Name: Cerebral Arterial Disease 12 14
Cerebral Arterial Diseases 42 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3527
MeSH 42 D002539
UMLS 69 C0007774

Summaries for Cerebral Arterial Disease

MalaCards based summary : Cerebral Arterial Disease, also known as cerebral arterial diseases, is related to cerebritis and moyamoya disease. An important gene associated with Cerebral Arterial Disease is RNF213 (Ring Finger Protein 213). The drugs Heparin and Tirofiban have been mentioned in the context of this disorder.

Related Diseases for Cerebral Arterial Disease

Diseases related to Cerebral Arterial Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
id Related Disease Score Top Affiliating Genes
1 cerebritis 30.3 NF1 SLC25A16
2 moyamoya disease 11.1
3 pars planitis 10.2 RNF213 RPSA
4 stroke, ischemic 10.1
5 ocular motility disease 10.1 NF1 RPSA
6 mobitz type ii atrioventricular block 10.1 MRAS SLC25A16
7 neuropathy, hereditary sensory, type ib 10.1 ACTA2 GUCY1A3 RNF213
8 artery disease 10.1
9 flat umbilicus familial 9.9 OBSCN RNF213
10 optic nerve glioma 9.9 ELN NF1
11 cavernous malformation 9.8 ACTA2 CDKN2B-AS1 ELN
12 cholesteatoma of attic 9.7 CDKN2B-AS1 ELN SOX17
13 aortic aneurysm 9.5
14 abdominal aortic aneurysm 9.5
15 neuronitis 9.5
16 aneurysm 9.5
17 choroid plexus cancer 8.2 ACTA2 ASAH1 CDKN2B-AS1 ELN GUCY1A3 MRAS

Graphical network of the top 20 diseases related to Cerebral Arterial Disease:



Diseases related to Cerebral Arterial Disease

Symptoms & Phenotypes for Cerebral Arterial Disease

Drugs & Therapeutics for Cerebral Arterial Disease

Drugs for Cerebral Arterial Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 731)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3 9005-49-6 772 46507594
2
Tirofiban Approved Phase 4 144494-65-5 60947
3
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3 51-43-4 5816
4
Ticlopidine Approved Phase 4,Phase 3,Phase 2 55142-85-3 5472
5
Atenolol Approved Phase 4,Phase 3 29122-68-7 2249
6
Valsartan Approved, Investigational Phase 4,Phase 2 137862-53-4 60846
7
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
8
Nimodipine Approved Phase 4,Phase 1,Phase 2 66085-59-4 4497
9
Dorzolamide Approved Phase 4 120279-96-1 3154 5284549
10
Timolol Approved Phase 4 26839-75-8 33624 5478
11
Citalopram Approved Phase 4,Phase 3 59729-33-8 2771
12
Cocaine Approved, Illicit Phase 4,Phase 1,Phase 2 50-36-2 5760 446220
13
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
14
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 1 137-58-6 3676
15
Ondansetron Approved Phase 4 99614-02-5 4595
16
Bosentan Approved, Investigational Phase 4,Phase 1,Phase 2 147536-97-8 104865
17
Dalteparin Approved Phase 4,Phase 3,Phase 2 9041-08-1
18 Nadroparin Approved Phase 4 9041-08-1
19
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
20
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-23-7 5754 657311
21
Metyrapone Approved Phase 4 54-36-4 4174
22
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 2078-54-8 4943
23
Remifentanil Approved Phase 4,Phase 3,Phase 2 132875-61-7 60815
24
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
25
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
26
Galantamine Approved Phase 4,Phase 3,Phase 2 357-70-0 9651 908828, 9651
27
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 69-65-8 453 6251
28
Warfarin Approved Phase 4,Phase 3,Phase 1 81-81-2 6691 54678486
29
Ethanol Approved Phase 4 64-17-5 702
30
Esmolol Approved Phase 4,Phase 3 103598-03-4, 81147-92-4 59768
31
Sertraline Approved Phase 4 79617-96-2 68617
32
Cilostazol Approved Phase 4,Phase 3,Phase 2 73963-72-1 2754
33
Dobutamine Approved Phase 4,Phase 2 34368-04-2 36811
34
Probucol Approved Phase 4 23288-49-5 4912
35
Everolimus Approved Phase 4,Phase 3,Phase 2 159351-69-6 6442177
36
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 33069-62-4 36314
37
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2 53123-88-9 5284616 6436030 46835353
38
Coal tar Approved Phase 4 8007-45-2
39
Pravastatin Approved Phase 4,Phase 3,Phase 2 81093-37-0 54687
40
Methylphenidate Approved, Investigational Phase 4,Phase 2,Phase 3 113-45-1 4158
41
Metformin Approved Phase 4,Phase 3,Phase 2 657-24-9 14219 4091
42
Yohimbine Approved, Vet_approved Phase 4,Phase 1 146-48-5 8969
43
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1 103-90-2 1983
44
Topiramate Approved Phase 4 97240-79-4 5284627
45
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
46
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
47
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
48
Methazolamide Approved Phase 4 554-57-4 4100
49
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
50
Nicergoline Approved Phase 4 27848-84-6 34040

Interventional clinical trials:

(show top 50) (show all 1751)
id Name Status NCT ID Phase
1 Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia Unknown status NCT00247533 Phase 4
2 Effect of BNP (Brain Natriuretic Peptides) on Endothelial Dysfunction Induced by Coronary Angioplasty Unknown status NCT00262574 Phase 4
3 Efficacy and Safety of Different Dose of Tirofiban in Interventional Treatment of Complex Coronary Artery Disease Unknown status NCT02294994 Phase 4
4 Early Warning and Optimization Strategy in Carotid Endarterectomy Unknown status NCT01210937 Phase 4
5 Sodium Bicarbonate in Cardiopulmonary Resuscitation Unknown status NCT01377337 Phase 4
6 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting Unknown status NCT01572623 Phase 4
7 SAPPHIRE Worldwide: Stenting and Angioplasty With Protection in Patients At High-Risk for Endarterectomy Unknown status NCT00403078 Phase 4
8 A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial Stenosis Unknown status NCT01553643 Phase 4
9 Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol Unknown status NCT02403349 Phase 4
10 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
11 Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis Unknown status NCT00772278 Phase 4
12 Nimodipine for Treating Acute Massive Cerebral Infarction Unknown status NCT02248233 Phase 4
13 Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit Unknown status NCT00862160 Phase 4
14 Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma Patients Unknown status NCT02053298 Phase 4
15 Study of Escitalopram Versus Placebo in the Treatment of Depressive Syndrome in Alzheimer’s Disease, Vascular Dementia, and Mixed Vascular and Alzheimer’s Dementia Unknown status NCT00229333 Phase 4
16 HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study Unknown status NCT01516658 Phase 4
17 Pharmacologic MRI in Cocaine Addiction Unknown status NCT01652378 Phase 4
18 The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis Unknown status NCT02480335 Phase 4
19 Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD Unknown status NCT01531829 Phase 4
20 Coronary Angioplasty in Octogenarians With Emergent Coronary Syndromes Unknown status NCT02126202 Phase 4
21 The Effectiveness and Safety of Butylphthalide Soft Capsules in Secondary Prevention of Ischemic Stroke Trial Unknown status NCT00724724 Phase 4
22 Safety and Efficacy of Heparin and Nadroparin in the Acute Phase of Ischemic Stroke Unknown status NCT01862978 Phase 4
23 Cortisol and Nutritional Sympathetic Responsiveness Unknown status NCT01620684 Phase 4
24 Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients Unknown status NCT00132223 Phase 4
25 Optimal Duration of DAPT Following Treatment With Endeavor (Zotarolimus-eluting Stent) in Real-world Japanese Patients Completed NCT01325935 Phase 4
26 A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease Completed NCT00178672 Phase 4
27 Nobori Dual Antiplatelet Therapy as Appropriate Duration Completed NCT01514227 Phase 4
28 The Safety and Efficacy of Cilostazol in Ischemic Stroke Patients With Peripheral Arterial Disease (SPAD Study) Completed NCT01188824 Phase 4
29 A Study of Stress Echocardiography in Post-Menopausal Women at Risk for Coronary Disease Completed NCT00162370 Phase 4
30 Atorvastatin in Acute Stroke Treatment Completed NCT02225834 Phase 4
31 Assessing the Effects of Omega-3 Supplementation on Some Serum BDNF، Follistatin، Irisin Levels in Men With CAD Completed NCT02382471 Phase 4
32 Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study) Completed NCT00287508 Phase 4
33 Invasive vs Conservative Strategies in Non-ST-elevation Acute Coronary Syndrome and Comorbidities Completed NCT01645943 Phase 4
34 Study of Cilostazol and Probucol Alone and in Combination on Atherosclerosis Related Biomarker---atherosclerosis Cerebral Infarction Patient as Study Subject Completed NCT00823875 Phase 4
35 The Dual Antiplatelet Therapy Study (DAPT Study) Completed NCT00977938 Phase 4
36 Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarterectomy Completed NCT02609087 Phase 4
37 Researching AXIUM Coiling Experience and Recanalization (RACER) Completed NCT00703794 Phase 4
38 The Study on Profile and Genetic Factors of Aspirin Resistance (ProGEAR Study) Completed NCT00250380 Phase 4
39 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function Completed NCT02691416 Phase 4
40 Carotid Revascularization With ev3 Arterial Technology Evolution Post Approval Study Completed NCT00530504 Phase 4
41 Vasomotor Reactivity In Cerebral Small Vessel Disease And New Approach To Treat Lacunar Stroke Completed NCT00163150 Phase 4
42 A Carotid Stenting Boston Scientific Surveillance Program Completed NCT00741091 Phase 4
43 Effects of Atorvastatin Versus Pravastatin on Platelet Inhibition by Clopidogrel Completed NCT00405717 Phase 4
44 Influence of Stimulant Medication on Brain Processes for Decision Making in Attention Deficit Hyperactivity Disorder Completed NCT01831622 Phase 4
45 Effects of Optimized Antiplatelet Treatment After Percutaneous Coronary Intervention Completed NCT00404781 Phase 4
46 Aneurysm Wall Histology Registry Completed NCT01444664 Phase 4
47 CAPTURE 2 Post-Marketing Registry Completed NCT00302237 Phase 4
48 CHOICE: Carotid Stenting For High Surgical-Risk Patients Completed NCT00406055 Phase 4
49 Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery Completed NCT01146301 Phase 4
50 Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study Completed NCT00723307 Phase 4

Search NIH Clinical Center for Cerebral Arterial Disease

Cochrane evidence based reviews: cerebral arterial diseases

Genetic Tests for Cerebral Arterial Disease

Anatomical Context for Cerebral Arterial Disease

Publications for Cerebral Arterial Disease

Articles related to Cerebral Arterial Disease:

(show all 15)
id Title Authors Year
1
Frequency and Risk Factors for Cerebral Arterial Disease in a HIV/AIDS Neuroimaging Cohort. ( 26751784 )
2016
2
Progressive Cortical Neuronal Damage and Chronic Hemodynamic Impairment in Atherosclerotic Major Cerebral Artery Disease. ( 27217506 )
2016
3
Nonatheroscleotic Isolated Middle Cerebral Artery Disease May Be Early Manifestation of Moyamoya Disease. ( 27507861 )
2016
4
Misery Perfusion, Blood Pressure Control, and 5-Year Stroke Risk in Symptomatic Major Cerebral Artery Disease. ( 25395413 )
2014
5
Associations of ankle-brachial index (ABI) with cerebral arterial disease and vascular events following ischemic stroke. ( 22652527 )
2012
6
Assessment of pial branches using 7-tesla MRI in cerebral arterial disease. ( 20185908 )
2010
7
Risk factors for stroke in different levels of cerebral arterial disease. ( 10529541 )
1999
8
High prevalence of unsuspected abdominal aortic aneurysm in patients with confirmed symptomatic peripheral or cerebral arterial disease. ( 8518892 )
1993
9
Occlusive cerebral arterial disease. ( 6839323 )
1983
10
Intracranial bypass surgery for cerebral arterial disease and the responsibility of the practicing physician. ( 462524 )
1979
11
Effect of ethyl apovincaminate on the cerebral circulation. Studies in patients with obliterative cerebral arterial disease. ( 1037221 )
1976
12
Cerebral arterial disease in children. An angiographic study of 40 cases. ( 5579392 )
1971
13
The significance of naturally occurring coronary and cerebral arterial disease in animals. ( 5253796 )
1968
14
Cerebral arterial disease. ( 14430850 )
1959
15
Cerebral arterial disease. ( 14417991 )
1959

Variations for Cerebral Arterial Disease

Expression for Cerebral Arterial Disease

Search GEO for disease gene expression data for Cerebral Arterial Disease.

Pathways for Cerebral Arterial Disease

GO Terms for Cerebral Arterial Disease

Biological processes related to Cerebral Arterial Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 blood circulation GO:0008015 8.62 ELN GUCY1A3

Sources for Cerebral Arterial Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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