MCID: CRB031
MIFTS: 29

Cerebral Arterial Disease

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Cerebral Arterial Disease

MalaCards integrated aliases for Cerebral Arterial Disease:

Name: Cerebral Arterial Disease 12 14
Cerebral Arterial Diseases 42 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3527
MeSH 42 D002539
UMLS 69 C0007774

Summaries for Cerebral Arterial Disease

MalaCards based summary : Cerebral Arterial Disease, also known as cerebral arterial diseases, is related to moyamoya disease and pars planitis. An important gene associated with Cerebral Arterial Disease is RNF213 (Ring Finger Protein 213), and among its related pathways/superpathways is Signaling in Gap Junctions. The drugs Heparin and Tirofiban have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and endothelial.

Related Diseases for Cerebral Arterial Disease

Diseases related to Cerebral Arterial Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
id Related Disease Score Top Affiliating Genes
1 moyamoya disease 11.1
2 pars planitis 10.5 RNF213 RPSA
3 ocular motility disease 10.3 NF1 RPSA
4 acute salpingo-oophoritis 10.3 ACTA2 RNF213
5 granulomatous myositis 10.3 NF1 SLC25A16
6 lung lymphoma 10.2 NF1 PKDREJ
7 stroke, ischemic 10.2
8 fuhrmann syndrome 10.1 ACTA2 GUCY1A3 RNF213
9 artery disease 10.1
10 cerebritis 10.1
11 mobitz type ii atrioventricular block 10.1 MRAS SLC25A16
12 fibular aplasia ectrodactyly 9.8 OBSCN RNF213
13 aortic aneurysm 9.5
14 abdominal aortic aneurysm 9.5
15 neuronitis 9.5
16 aneurysm 9.5
17 unverricht-lundborg syndrome 5.3 ACTA2 ASAH1 CDKN2B-AS1 GUCY1A3 MRAS NF1

Graphical network of the top 20 diseases related to Cerebral Arterial Disease:



Diseases related to Cerebral Arterial Disease

Symptoms & Phenotypes for Cerebral Arterial Disease

Drugs & Therapeutics for Cerebral Arterial Disease

Drugs for Cerebral Arterial Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 458)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3 9005-49-6 772 46507594
2
Tirofiban Approved Phase 4 144494-65-5 60947
3
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
4 Racepinephrine Approved Phase 4
5
Ticlopidine Approved Phase 4,Phase 3,Phase 2 55142-85-3 5472
6
Atenolol Approved Phase 4,Phase 3 29122-68-7 2249
7
Valsartan Approved, Investigational Phase 4,Phase 2 137862-53-4 60846
8
Benzocaine Approved Phase 4,Phase 2,Phase 3,Early Phase 1 1994-09-7, 94-09-7 2337
9
Nimodipine Approved Phase 4,Phase 1,Phase 2 66085-59-4 4497
10
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
11
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 2078-54-8 4943
12
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2 28523-86-6 5206
13
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
14
Ethanol Approved Phase 4 64-17-5 702
15
Sertraline Approved Phase 4 79617-96-2 68617
16
Cilostazol Approved Phase 4,Phase 3,Phase 2 73963-72-1 2754
17
Dobutamine Approved Phase 4 34368-04-2 36811
18
Probucol Approved Phase 4 23288-49-5 4912
19
Everolimus Approved Phase 4,Phase 3 159351-69-6 6442177
20
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3 33069-62-4 36314
21
Sirolimus Approved, Investigational Phase 4,Phase 3 53123-88-9 5284616 6436030 46835353
22
Remifentanil Approved Phase 4 132875-61-7 60815
23
Pravastatin Approved Phase 4 81093-37-0 54687
24
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
25
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
26
Metformin Approved Phase 4,Phase 2 657-24-9 14219 4091
27
Yohimbine Approved, Vet_approved Phase 4 146-48-5 8969
28
Lisinopril Approved, Investigational Phase 4,Phase 3 83915-83-7, 76547-98-3 5362119
29
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
30
Propranolol Approved, Investigational Phase 4 525-66-6 4946
31
Acetaminophen Approved Phase 4 103-90-2 1983
32
Ticagrelor Approved Phase 4,Phase 3,Phase 2 274693-27-5 9871419
33
Bivalirudin Approved, Investigational Phase 4,Phase 2,Phase 3 128270-60-0 16129704
34
Rivaroxaban Approved Phase 4,Phase 3 366789-02-8
35
Warfarin Approved Phase 4 81-81-2 6691 54678486
36
Glyburide Approved Phase 4 10238-21-8 3488
37 Piracetam Approved Phase 4 7491-74-9
38
Abciximab Approved Phase 4 143653-53-6
39
Ranibizumab Approved Phase 4 347396-82-1 459903
40
Candesartan Approved Phase 4 139481-59-7 2541
41
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3,Phase 2 120202-66-6, 113665-84-2 60606
42
Choline Approved, Nutraceutical Phase 4,Phase 3 62-49-7 305
43 tannic acid Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Early Phase 1
44
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
45
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3 59-67-6 938
46
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3 98-92-0 936
47
Angiotensin II Investigational Phase 4,Phase 3,Phase 2 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
48
Corticosterone Experimental Phase 4 50-22-6 5753
49 Natriuretic Agents Phase 4,Phase 3,Phase 2,Phase 1
50 Natriuretic Peptide, Brain Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 741)

id Name Status NCT ID Phase Drugs
1 Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia Unknown status NCT00247533 Phase 4
2 Effect of BNP (Brain Natriuretic Peptides) on Endothelial Dysfunction Induced by Coronary Angioplasty Unknown status NCT00262574 Phase 4 Nesiritide,
3 Efficacy and Safety of Different Dose of Tirofiban in Interventional Treatment of Complex Coronary Artery Disease Unknown status NCT02294994 Phase 4 tirofiban
4 Early Warning and Optimization Strategy in Carotid Endarterectomy Unknown status NCT01210937 Phase 4
5 Sodium Bicarbonate in Cardiopulmonary Resuscitation Unknown status NCT01377337 Phase 4 sodium bicarbonate
6 Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting Unknown status NCT01572623 Phase 4 Clopidogrel;Atorvastatin
7 SAPPHIRE Worldwide: Stenting and Angioplasty With Protection in Patients At High-Risk for Endarterectomy Unknown status NCT00403078 Phase 4
8 Comparison of Staged Angioplasty and Routine Single-stage Stenting (CAS) in the Treatment of Carotid Artery Stenosis Unknown status NCT02224209 Phase 4
9 A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial Stenosis Unknown status NCT01553643 Phase 4 Chinese Herb Huang-Chi-Wu-Wu-Tang;placebo
10 Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol Unknown status NCT02403349 Phase 4 Fimasartan;Valsartan;Atenolol
11 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
12 Nimodipine for Treating Acute Massive Cerebral Infarction Unknown status NCT02248233 Phase 4 Nimodipine;Saline + citicoline
13 Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit Unknown status NCT00862160 Phase 4
14 Optimal Duration of DAPT Following Treatment With Endeavor (Zotarolimus-eluting Stent) in Real-world Japanese Patients Completed NCT01325935 Phase 4 Clopidogrel
15 A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease Completed NCT00178672 Phase 4
16 Nobori Dual Antiplatelet Therapy as Appropriate Duration Completed NCT01514227 Phase 4 Aspirin or thienopyridine;Aspirin and thienopyridine
17 The Safety and Efficacy of Cilostazol in Ischemic Stroke Patients With Peripheral Arterial Disease (SPAD Study) Completed NCT01188824 Phase 4 Cilostazol
18 A Study of Stress Echocardiography in Post-Menopausal Women at Risk for Coronary Disease Completed NCT00162370 Phase 4 Perflutren Lipid Microsphere Injectable Suspension
19 Atorvastatin in Acute Stroke Treatment Completed NCT02225834 Phase 4 Atorvastatin
20 Assessing the Effects of Omega-3 Supplementation on Some Serum BDNF، Follistatin، Irisin Levels in Men With CAD Completed NCT02382471 Phase 4
21 Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study) Completed NCT00287508 Phase 4
22 Invasive vs Conservative Strategies in Non-ST-elevation Acute Coronary Syndrome and Comorbidities Completed NCT01645943 Phase 4
23 Study of Cilostazol and Probucol Alone and in Combination on Atherosclerosis Related Biomarker---atherosclerosis Cerebral Infarction Patient as Study Subject Completed NCT00823875 Phase 4 Cilostazol group;Probucol group;Cilostazol + Probucol group;control group
24 The Dual Antiplatelet Therapy Study (DAPT Study) Completed NCT00977938 Phase 4 Placebo & Aspirin;Clopidogrel & Aspirin, Prasugrel & Aspirin
25 Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarterectomy Completed NCT02609087 Phase 4 Sevoflurane;Propofol
26 The Study on Profile and Genetic Factors of Aspirin Resistance (ProGEAR Study) Completed NCT00250380 Phase 4
27 Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function Completed NCT02691416 Phase 4 propofol postconditioning;sevoflurane
28 Carotid Revascularization With ev3 Arterial Technology Evolution Post Approval Study Completed NCT00530504 Phase 4
29 Vasomotor Reactivity In Cerebral Small Vessel Disease And New Approach To Treat Lacunar Stroke Completed NCT00163150 Phase 4 Atorvastatin
30 A Carotid Stenting Boston Scientific Surveillance Program Completed NCT00741091 Phase 4
31 Effects of Atorvastatin Versus Pravastatin on Platelet Inhibition by Clopidogrel Completed NCT00405717 Phase 4 atorvastatin,pravastatin
32 Influence of Stimulant Medication on Brain Processes for Decision Making in Attention Deficit Hyperactivity Disorder Completed NCT01831622 Phase 4 Ritalin;Placebo
33 Effects of Optimized Antiplatelet Treatment After Percutaneous Coronary Intervention Completed NCT00404781 Phase 4 cilostazol in addition to aspirin and clopidogrel
34 Aneurysm Wall Histology Registry Completed NCT01444664 Phase 4
35 CAPTURE 2 Post-Marketing Registry Completed NCT00302237 Phase 4
36 CHOICE: Carotid Stenting For High Surgical-Risk Patients Completed NCT00406055 Phase 4
37 Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery Completed NCT01146301 Phase 4 Clopidogrel
38 Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study Completed NCT00723307 Phase 4 Metformin;Placebo
39 Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis Completed NCT00772278 Phase 4
40 The Effect of an α2-Adrenoceptor Antagonist (Yohimbine) on Dynamic Autoregulation in the Human Middle Cerebral Artery and Ophthalmic Artery Completed NCT00814047 Phase 4 Yohimbine hydrochloride
41 Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial Completed NCT00110448 Phase 4 Aspirin;No aspirin
42 Effect of Cilostazol in the Acute Lacunar Infarction Based on Pulsatility Index of Transcranial Doppler Completed NCT00741286 Phase 4 Aspirin;cilostazol
43 The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT) Completed NCT01341730 Phase 4 Atorvastatin 20mg;Atorvastatin 20 mg + Pioglitazone 30 mg
44 Cilostazol Verse Asprin for Vascular Dementia in Poststroke Patients With White Matter Lesions Completed NCT00847860 Phase 4 Cilostazol;Aspirin
45 Reducing Total Cardiovascular Risk in an Urban Community Completed NCT00241904 Phase 4 Antiplatelet Agents;Beta Blocker;ACE Inhibitors
46 Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit Completed NCT01948505 Phase 4 Intravenous acetaminophen;Placebo for IV acetaminophen
47 Near Infrared Spectroscopy (NIRS) and Superior Mesenteric Artery (SMA) Doppler Patterns as Predictor of Feeding Tolerance in Very Low Birth Weight (VLBW) IntraUterine Growth Restricted (IUGR) and NON IUGR Infants Completed NCT01341236 Phase 4
48 Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Carotid Intima-media Thickness (CIMT) Completed NCT01203982 Phase 4 Rosuvastatin;Rosuvastatin
49 Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease Study Recruiting NCT02642419 Phase 4 Rivaroxaban and single antiplatelet drug (aspirin, clopidogrel or prasugrel);Rivaroxaban
50 Registry for Estimation of Warfarin and Rivaroxaban in Atrial Fibrillation Patients With Coronary Stent Implantation Recruiting NCT02024230 Phase 4 Warfarin or Rivaroxaban

Search NIH Clinical Center for Cerebral Arterial Disease

Cochrane evidence based reviews: cerebral arterial diseases

Genetic Tests for Cerebral Arterial Disease

Anatomical Context for Cerebral Arterial Disease

MalaCards organs/tissues related to Cerebral Arterial Disease:

39
Brain, Heart, Endothelial, Bone, Kidney, Testes, Spinal Cord

Publications for Cerebral Arterial Disease

Articles related to Cerebral Arterial Disease:

(show all 15)
id Title Authors Year
1
Nonatheroscleotic Isolated Middle Cerebral Artery Disease May Be Early Manifestation of Moyamoya Disease. ( 27507861 )
2016
2
Progressive Cortical Neuronal Damage and Chronic Hemodynamic Impairment in Atherosclerotic Major Cerebral Artery Disease. ( 27217506 )
2016
3
Frequency and Risk Factors for Cerebral Arterial Disease in a HIV/AIDS Neuroimaging Cohort. ( 26751784 )
2016
4
Misery Perfusion, Blood Pressure Control, and 5-Year Stroke Risk in Symptomatic Major Cerebral Artery Disease. ( 25395413 )
2014
5
Associations of ankle-brachial index (ABI) with cerebral arterial disease and vascular events following ischemic stroke. ( 22652527 )
2012
6
Assessment of pial branches using 7-tesla MRI in cerebral arterial disease. ( 20185908 )
2010
7
Risk factors for stroke in different levels of cerebral arterial disease. ( 10529541 )
1999
8
High prevalence of unsuspected abdominal aortic aneurysm in patients with confirmed symptomatic peripheral or cerebral arterial disease. ( 8518892 )
1993
9
Occlusive cerebral arterial disease. ( 6839323 )
1983
10
Intracranial bypass surgery for cerebral arterial disease and the responsibility of the practicing physician. ( 462524 )
1979
11
Effect of ethyl apovincaminate on the cerebral circulation. Studies in patients with obliterative cerebral arterial disease. ( 1037221 )
1976
12
Cerebral arterial disease in children. An angiographic study of 40 cases. ( 5579392 )
1971
13
The significance of naturally occurring coronary and cerebral arterial disease in animals. ( 5253796 )
1968
14
Cerebral arterial disease. ( 14430850 )
1959
15
Cerebral arterial disease. ( 14417991 )
1959

Variations for Cerebral Arterial Disease

Expression for Cerebral Arterial Disease

Search GEO for disease gene expression data for Cerebral Arterial Disease.

Pathways for Cerebral Arterial Disease

Pathways related to Cerebral Arterial Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.19 ACTA2 GUCY1A3 MRAS

GO Terms for Cerebral Arterial Disease

Sources for Cerebral Arterial Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....