MCID: CRB005
MIFTS: 29

Cerebral Arteritis malady

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Cerebral Arteritis

Summaries for Cerebral Arteritis

MalaCards based summary : Cerebral Arteritis is related to cerebritis and facial nerve neoplasm. An important gene associated with Cerebral Arteritis is COL4A3 (Collagen Type IV Alpha 3 Chain), and among its related pathways/superpathways is Primary immunodeficiency. The drugs Prednisone and Azathioprine have been mentioned in the context of this disorder.

Related Diseases for Cerebral Arteritis

Diseases related to Cerebral Arteritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 198)
id Related Disease Score Top Affiliating Genes
1 cerebritis 10.2
2 facial nerve neoplasm 10.1 CD40LG KANTR
3 spastic ataxia 7, autosomal dominant 10.1 CD40LG KANTR
4 spotted fever 10.1 CD40LG KANTR
5 anal canal adenocarcinoma 10.1 CD40LG KANTR
6 oropharyngeal anthrax 10.1 CD40LG KANTR
7 benign paroxysmal positional nystagmus 10.1 CD40LG KANTR
8 cardiovascular cancer 10.1 CD40LG KANTR
9 hidrocystoma 10.1 CD40LG KANTR
10 generalized dystonia 10.1 CD40LG KANTR
11 hypolipoproteinemia 10.1 CD40LG KANTR
12 central retinal artery occlusion 10.1 CD40LG KANTR
13 placental insufficiency 10.1 CD40LG KANTR
14 gonococcal spondylitis 10.1 CD79A KANTR
15 pancreatic acinar cell adenocarcinoma 10.1 CD79A KANTR
16 right bundle branch block 10.1 CD79A KANTR
17 eosinophilic fasciitis 10.0 CD79A COL4A3
18 compensatory emphysema 10.0 CD79A KANTR
19 alcoholic neuropathy 10.0 CD40LG CD79A
20 camptodactyly vertebral fusion 10.0 CD40LG CD79A
21 spinal polio 10.0 CD40LG CD79A
22 rabies 10.0 CD40LG CD79A
23 unilateral retinoblastoma 10.0 CD40LG CD79A
24 mesangial proliferative glomerulonephritis 10.0 CD40LG CD79A
25 delta chain disease 10.0 CD40LG CD79A
26 discitis 10.0 CD40LG CD79A
27 trichostrongyloidiasis 10.0 CD40LG CD79A
28 colloid adenoma 10.0 CD40LG CD79A
29 heart septal defect 10.0 CD40LG CD79A
30 cutaneous polyarteritis nodosa 10.0 CD40LG CD79A
31 mild pre-eclampsia 10.0 CD40LG CD79A
32 retinal microaneurysm 10.0 CD40LG CD79A
33 pediatric meningioma 10.0 CD40LG CD79A
34 tonsil cancer 10.0 CD40LG CD79A
35 indomethacin antenatal infection 10.0 CD40LG CD79A
36 postcricoid region cancer 10.0 CD40LG CD79A
37 beach ear 10.0 CD40LG CD79A
38 acute kidney tubular necrosis 10.0 CD40LG CD79A
39 atheroembolism of kidney 10.0 CD40LG CD79A
40 partial sensory epilepsy 10.0 CD40LG CD79A
41 ritscher-schinzel syndrome 1 10.0 CD40LG CD79A
42 diabetic angiopathy 10.0 CD40LG CD79A
43 endocarditis 10.0 CD40LG CD79A
44 muscular dystrophy 10.0 CD40LG CD79A
45 dumping syndrome 10.0 CD40LG CD79A
46 striatonigral degeneration 10.0 CD40LG CD79A
47 ciliary body spindle cell melanoma 10.0 CD40LG CD79A
48 purulent endophthalmitis 10.0 CD40LG CD79A
49 mu chain disease 10.0 CD40LG CD79A
50 generalized atherosclerosis 10.0 CD40LG CD79A

Comorbidity relations with Cerebral Arteritis via Phenotypic Disease Network (PDN):


Acute Cystitis Hypertension, Essential
Temporal Arteritis

Graphical network of the top 20 diseases related to Cerebral Arteritis:



Diseases related to Cerebral Arteritis

Symptoms & Phenotypes for Cerebral Arteritis

Drugs & Therapeutics for Cerebral Arteritis

Drugs for Cerebral Arteritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 84)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
2
Azathioprine Approved Phase 4,Phase 3 446-86-6 2265
3
Cyclophosphamide Approved, Investigational Phase 4,Phase 2 50-18-0, 6055-19-2 2907
4
Methotrexate Approved Phase 4,Phase 3,Phase 2 1959-05-2, 59-05-2 126941
5
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
6
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
7
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
8
Mycophenolic acid Approved Phase 4 24280-93-1 446541
9
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
10
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2 58-05-9 54575, 6560146 143
11 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
12 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
13 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
14 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
15 Hormones Phase 4,Phase 3,Phase 2,Phase 1
16 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
17 Alkylating Agents Phase 4,Phase 2
18 Antimetabolites Phase 4,Phase 3,Phase 2
19 Antimetabolites, Antineoplastic Phase 4,Phase 3,Phase 2
20 Antineoplastic Agents, Alkylating Phase 4,Phase 2
21 Antirheumatic Agents Phase 4,Phase 3,Phase 2
22 Immunosuppressive Agents Phase 4,Phase 3,Phase 2
23 Antiemetics Phase 4,Phase 2,Phase 3
24 Autonomic Agents Phase 4,Phase 2,Phase 3
25 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
26 Folic Acid Antagonists Phase 4,Phase 3,Phase 2
27 Gastrointestinal Agents Phase 4,Phase 3,Phase 2
28 Methylprednisolone acetate Phase 4,Phase 2,Phase 3
29 Methylprednisolone Hemisuccinate Phase 4,Phase 2,Phase 3
30 Neuroprotective Agents Phase 4,Phase 2,Phase 3
31 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
32 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
33 Prednisolone acetate Phase 4,Phase 2,Phase 3
34 Prednisolone hemisuccinate Phase 4,Phase 2,Phase 3
35 Prednisolone phosphate Phase 4,Phase 2,Phase 3
36 Protective Agents Phase 4,Phase 2,Phase 3
37 Vitamin B Complex Phase 4,Phase 3,Phase 2
38 Anti-Bacterial Agents Phase 4
39 Antibiotics, Antitubercular Phase 4
40 Folate Nutraceutical Phase 4,Phase 3,Phase 2
41 Vitamin B9 Nutraceutical Phase 4,Phase 3,Phase 2
42
Infliximab Approved Phase 3,Phase 2 170277-31-3
43
Hydroxychloroquine Approved Phase 3 118-42-3 3652
44
Adalimumab Approved Phase 3 331731-18-1 16219006
45
Alendronate Approved Phase 3 121268-17-5, 66376-36-1 2088
46
Etanercept Approved, Investigational Phase 3 185243-69-0
47
Alfacalcidol Approved, Nutraceutical Phase 3 41294-56-8 5282181
48 Anti-Infective Agents Phase 3
49 Pharmaceutical Solutions Phase 3
50 Antimalarials Phase 3

Interventional clinical trials:

(show top 50) (show all 65)
id Name Status NCT ID Phase
1 Steroids Pharmacokinetics and the Response to Prednisone Therapy in Giant Cell Arteritis Unknown status NCT01400464 Phase 4
2 CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis Factors Unknown status NCT00400075 Phase 4
3 Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia Rheumatica Patients Completed NCT01169597 Phase 4
4 Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years Completed NCT00307671 Phase 4
5 Infliximab Therapy in Patients With Refractory Polymyalgia Rheumatica Unknown status NCT01423591 Phase 3
6 Hydroxychloroquine in Giant Cell Arteritis Completed NCT00430807 Phase 3
7 HECTHOR: Humira to Spare Steroids in Giant Cell Arteritis Completed NCT00305539 Phase 3
8 Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol. Completed NCT00138983 Phase 3
9 Timed Release Tablet Prednisone in Polymyalgia Rheumatica Completed NCT00836810 Phase 2, Phase 3
10 Etanercept Treatment in the Early Course of Polymyalgia Rheumatica Completed NCT00524381 Phase 3
11 Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) Completed NCT00647166 Phase 3
12 Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis Recruiting NCT02531633 Phase 3
13 Safety and Efficacy of tocilizuMAb Versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence SEMAPHORE Recruiting NCT02908217 Phase 3
14 An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA) Active, not recruiting NCT01791153 Phase 3
15 Giant Cell Arteritis and Anakinra Trial Not yet recruiting NCT02902731 Phase 3
16 Efficacy and Safety Study of Sirukumab in Subjects With Polymyalgia Rheumatica Not yet recruiting NCT02899026 Phase 3
17 A Study Assessing the Efficacy and Safety of Lodotra® Compared to Prednisone IR in Subjects Suffering From PMR Terminated NCT01821040 Phase 3
18 Evaluation of Tocilizumab as an add-on Therapy to Corticoids in Horton's Disease: Proof of Concept Study. Unknown status NCT01910038 Phase 2
19 Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides Unknown status NCT00751517 Phase 2
20 Tocilizumab for Patients With Giant Cell Arteritis Completed NCT01450137 Phase 2
21 Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis Completed NCT00556439 Phase 2
22 Phase II Randomized Study of Glucocorticoids With or Without Methotrexate for Treatment of Giant Cell Arteritis Completed NCT00004686 Phase 2
23 Tocilizumab Effect iN pOlymyalgia Rheumatica Completed NCT01713842 Phase 2
24 Study of Tocilizumab to Treat Polymyalgia Rheumatica Completed NCT01396317 Phase 2
25 Baricitinib in Relapsing Giant Cell Arteritis Recruiting NCT03026504 Phase 2
26 Ustekinumab for the Treatment of Giant Cell Arteritis Recruiting NCT02955147 Phase 1, Phase 2
27 A Study of the Gut Barrier and Blood Vessel Inflammation in Individuals With and Without HIV Recruiting NCT02431325 Phase 2
28 A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Giant Cell Arteritis Terminated NCT00076726 Phase 2
29 Delayed Release Prednisone in PMR Terminated NCT02702778 Phase 2
30 A 3-arm Proof of Concept Study of AIN457, ACZ885 or Corticosteroids in Patients With Polymyalgia Rheumatica Terminated NCT01364389 Phase 2
31 MRI Superficial Temporal Artery Completed NCT00188448 Phase 1
32 Diagnostic Study of Temporal Arteritis Unknown status NCT01130857
33 Sensitivity and Specificity of Color Doppler Directed Temporal Artery Biopsy as Compared to Standard Random Biopsy in the Diagnosis of Temporal Arteritis Unknown status NCT00361192 Early Phase 1
34 Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases Unknown status NCT00006055
35 Study of the T CD8 Immune Response in Horton's Disease Unknown status NCT02158208
36 Efficacy of Micro-Pulse Steroid Therapy as Induction Therapy in Patients With Polymyalgia Rheumatica Unknown status NCT00982332
37 Quantitative and Functional Study of TH17 Lymphocytes in Horton's Disease (HD) Unknown status NCT02065297
38 ADDICTAO: Psychological and Addictive Profile of Patients With Buerger's Disease Completed NCT01064206
39 Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis Completed NCT01795456
40 Temporal Artery Biopsy vs ULtrasound in Diagnosis of GCA (TABUL) Completed NCT00974883
41 Educational Needs of Patients With Systemic Vasculitis Completed NCT02190929
42 Reproductive Health in Men and Women With Vasculitis Completed NCT02176070
43 Impact of Vasculitis on Employment and Income Completed NCT02476292
44 Vasculitis Illness Perception (VIP) Study Completed NCT02190916
45 Lymphocyte and Cytokine Disturbances in Polymyalgia Rheumatica Completed NCT02888496
46 Prediction of Femoral Revascularization Quality Using the Somatic NIRS Signal Recruiting NCT02337920
47 Pediatric Vasculitis Initiative Recruiting NCT02006134
48 Determining Disease Activity Biomarkers in Individuals With Giant Cell Arteritis Recruiting NCT00315497
49 Biomarkers in Giant Cells Arteritis Recruiting NCT02844023
50 Prospective Follow-up Study of the Aortic Diameter in Patients With Giant Cell Arteritis Recruiting NCT01588483

Search NIH Clinical Center for Cerebral Arteritis

Genetic Tests for Cerebral Arteritis

Anatomical Context for Cerebral Arteritis

Publications for Cerebral Arteritis

Articles related to Cerebral Arteritis:

(show all 29)
id Title Authors Year
1
Mucormycosis cerebral arteritis mimicking a flare in ANCA-associated vasculitis. ( 23347635 )
2013
2
Primary cerebral arteritis in a young girl: an unusual cause of acute recurrent neurological deterioration. ( 21783391 )
2012
3
Cerebral arteritis with extremely late onset secondary to bacterial meningitis - case report - . ( 21515955 )
2011
4
Cerebral arteritis following methylphenidate use. ( 10805196 )
2000
5
Acute reversible cerebral arteritis associated with parenteral ephedrine use. ( 10545695 )
1999
6
Frequency of cerebral arteritis in subarachnoid cysticercosis: an angiographic study. ( 9445339 )
1998
7
Cerebral arteritis associated with oral use of phenylpropanolamine: report of a case. ( 7613235 )
1995
8
Optic neuropathy, headache, and diplopia with MRI suggestive of cerebral arteritis in relapsing polychondritis. ( 8574363 )
1995
9
Ginseng-associated cerebral arteritis. ( 7723981 )
1995
10
Contrast-enhanced MR of cerebral arteritis: intravascular enhancement related to flow stasis within areas of focal arterial ectasia. ( 1595457 )
1992
11
Is cerebral arteritis the cause of the Landau-Kleffner syndrome? Four cases in childhood with angiographic study. ( 1373338 )
1992
12
Cerebral arteritis with unusual distribution. ( 2354606 )
1990
13
Cerebral arteritis and oral methylphenidate. ( 2894511 )
1988
14
Cytological investigation of CSF in leptospiral cerebral arteritis. ( 3249356 )
1988
15
Cerebral arteritis and bacterial meningitis. ( 6721722 )
1984
16
Leptospiral cerebral arteritis: report of 4 autopsy cases. ( 6700927 )
1984
17
Neoplastic angioendotheliosis: a case with spontaneous regression and radiographic appearance of cerebral arteritis. ( 6681558 )
1983
18
Moyamoya disease caused by leptospiral cerebral arteritis. ( 6775894 )
1980
19
Coccidioidal meningitis complicated by cerebral arteritis and infarction. ( 7399519 )
1980
20
Cerebral arteritis in scleroderma. ( 505502 )
1979
21
Cerebral arteritis in cat-scratch disease. ( 573385 )
1979
22
Cerebral arteritis associated with ulcerative colitis. ( 571999 )
1979
23
Cerebral arteritis. Angiographic and pathologic study. ( 717833 )
1978
24
Hemorrhagic complications of cerebral arteritis. ( 26323 )
1978
25
Cerebral arteritis associated with heroin abuse. ( 732746 )
1978
26
Hemorrhagic complications of cerebral arteritis. ( 889496 )
1977
27
Candida meningitis; with cerebral arteritis. ( 1055887 )
1975
28
Cerebral arteritis: classification. ( 4147505 )
1973
29
Cerebral arteritis and phlebitis in pneumococcal meningitis. ( 20297306 )
1946

Variations for Cerebral Arteritis

Expression for Cerebral Arteritis

Search GEO for disease gene expression data for Cerebral Arteritis.

Pathways for Cerebral Arteritis

Pathways related to Cerebral Arteritis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.19 CD40LG CD79A

GO Terms for Cerebral Arteritis

Biological processes related to Cerebral Arteritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 B cell differentiation GO:0030183 8.96 CD40LG CD79A
2 B cell proliferation GO:0042100 8.62 CD40LG CD79A

Sources for Cerebral Arteritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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