MCID: CRB004
MIFTS: 42

Cerebral Artery Occlusion

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Cerebral Artery Occlusion

MalaCards integrated aliases for Cerebral Artery Occlusion:

Name: Cerebral Artery Occlusion 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:10127
ICD9CM 35 434 434.9
UMLS 69 C0028790

Summaries for Cerebral Artery Occlusion

MalaCards based summary : Cerebral Artery Occlusion is related to cerebritis and ischemia. An important gene associated with Cerebral Artery Occlusion is BDNF (Brain Derived Neurotrophic Factor), and among its related pathways/superpathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. The drugs Dalteparin and Heparin have been mentioned in the context of this disorder. Affiliated tissues include brain, endothelial and cortex, and related phenotypes are cellular and growth/size/body region

Related Diseases for Cerebral Artery Occlusion

Diseases related to Cerebral Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
id Related Disease Score Top Affiliating Genes
1 cerebritis 11.0
2 ischemia 10.4
3 intestinal impaction 10.4 BDNF GDNF
4 ileocolitis 10.4 GDNF NOS3
5 mobitz type ii atrioventricular block 10.4 BDNF NOS2
6 neuronitis 10.3
7 eyelid degenerative disease 10.3 NOS2 ODC1
8 warman mulliken hayward syndrome 10.3 CNTF ODC1
9 esophageal leukoplakia 10.2 NOS2 NOS3
10 retroperitoneal sarcoma 10.2 NOS2 NOS3
11 polymicrogyria, bilateral frontoparietal 10.1 NOS2 NOS3
12 brain edema 10.1
13 brain injury 10.1
14 spinal stenosis 10.0 BDNF GDNF NOS2
15 hypoxia 10.0
16 prostate carcinoma in situ 10.0 BDNF GDNF NOS2
17 viral hepatitis 10.0 NOS2 NOS3
18 plantar fascial fibromatosis 10.0 IL1RN ODC1
19 aneurysm 10.0
20 endotheliitis 10.0
21 cellular schwannoma 9.9 ADAMTS1 GDNF
22 brain ischemia 9.9
23 mucopolysaccharidosis iii 9.9 BDNF CNTF GDNF
24 mutism 9.9
25 hyperglycemia 9.9
26 akinetic mutism 9.9
27 carotid artery dissection 9.9
28 parkinson disease, late-onset 9.8 BDNF CNTF GDNF
29 hirschsprung disease 1 9.8 BDNF GDNF
30 endocarditis 9.7
31 hemiplegia 9.7
32 choroiditis 9.7
33 moyamoya disease 9.7
34 cervicitis 9.7
35 cerebral hypoxia 9.7
36 neonatal stroke 9.7
37 benign struma ovarii 9.7 ADAMTS1 NOS2
38 subacute leukemia 9.7 IL1RN NOS2 NOS3
39 ragweed sensitivity 9.7 IL1RN NOS2
40 long qt syndrome 5 9.6 BDNF CNTF GDNF
41 osteopetrosis 9.6
42 retinitis 9.6
43 ischemic retinopathy 9.6
44 thrombocytopenia 9.6
45 artery disease 9.6
46 infective endocarditis 9.6
47 myocardial infarction 9.6
48 thrombosis 9.6
49 coronary artery disease 9.6
50 pneumonia 9.6

Graphical network of the top 20 diseases related to Cerebral Artery Occlusion:



Diseases related to Cerebral Artery Occlusion

Symptoms & Phenotypes for Cerebral Artery Occlusion

MGI Mouse Phenotypes related to Cerebral Artery Occlusion:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.7 BDNF CNTF GDNF IL1RN NOS2 NOS3
2 growth/size/body region MP:0005378 9.5 BDNF GDNF IL1RN NOS2 NOS3 ODC1
3 reproductive system MP:0005389 9.1 ADAMTS1 BDNF GDNF IL1RN NOS2 NOS3

Drugs & Therapeutics for Cerebral Artery Occlusion

Drugs for Cerebral Artery Occlusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 111)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dalteparin Approved Phase 4 9005-49-6
2
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
3 Nadroparin Approved Phase 4 9041-08-1
4
Prilocaine Approved Phase 4 721-50-6 4906
5
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
6
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 1 50-78-2 2244
7
Abciximab Approved Phase 4 143653-53-6
8
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
9 Anticoagulants Phase 4,Phase 2
10 calcium heparin Phase 4
11 Calcium, Dietary Phase 4,Phase 2,Phase 3,Phase 1
12 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Phase 1
13 Heparin, Low-Molecular-Weight Phase 4
14 Plasminogen Phase 4,Phase 3,Phase 2,Phase 1
15 Tissue Plasminogen Activator Phase 4,Phase 3,Phase 2,Phase 1
16 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1
17 Anticholesteremic Agents Phase 4
18 Antimetabolites Phase 4
19 Atorvastatin Calcium Phase 4 134523-03-8
20 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
21 Hypolipidemic Agents Phase 4
22 Lipid Regulating Agents Phase 4
23 Anesthetics, Local Phase 4,Phase 1
24 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Phase 1
25 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
26 Platelet Aggregation Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
27 Antibodies Phase 4
28 Antibodies, Monoclonal Phase 4
29 Immunoglobulin Fab Fragments Phase 4
30 Immunoglobulins Phase 4
31
Reteplase Approved Phase 3 133652-38-7 65820
32
Tenecteplase Approved Phase 3,Phase 2 191588-94-0
33
Ticlopidine Approved Phase 3 55142-85-3 5472
34
Ticagrelor Approved Phase 3 274693-27-5 9871419
35
Xylometazoline Approved Phase 3 526-36-3 5709
36
Magnesium Sulfate Approved, Vet_approved Phase 2, Phase 3,Phase 1 7487-88-9 24083
37 Pharmaceutical Solutions Phase 2, Phase 3
38 Neurotransmitter Agents Phase 3,Phase 2,Phase 1
39 Adrenergic Agents Phase 2, Phase 3
40 Autonomic Agents Phase 2, Phase 3
41 Analgesics Phase 3,Phase 2,Phase 1
42 Analgesics, Non-Narcotic Phase 3,Phase 1
43 Anti-Inflammatory Agents Phase 3,Phase 1
44 Anti-Inflammatory Agents, Non-Steroidal Phase 3,Phase 1
45 Antipyretics Phase 3,Phase 1
46 Antirheumatic Agents Phase 3,Phase 1
47 Cyclooxygenase Inhibitors Phase 3,Phase 1
48 Cytochrome P-450 Enzyme Inhibitors Phase 3
49 Purinergic P2 Receptor Antagonists Phase 3
50 Purinergic P2Y Receptor Antagonists Phase 3

Interventional clinical trials:

(show top 50) (show all 103)

id Name Status NCT ID Phase Drugs
1 A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial Stenosis Unknown status NCT01553643 Phase 4 Chinese Herb Huang-Chi-Wu-Wu-Tang;placebo
2 Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD Unknown status NCT01531829 Phase 4 Recombinant tissue plasminogen activator (rt-PA);Low Molecular Weight Heparin
3 Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia Unknown status NCT00247533 Phase 4
4 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
5 Atorvastatin in Acute Stroke Treatment Completed NCT02225834 Phase 4 Atorvastatin
6 Cerebral Embolic Load in Patients Undergoing Surgical Aortic Valve Replacement: A Comparison of the Conventional With the Minimized Extracorporeal Circulation Technique Using Transcranial Doppler Ultrasound Completed NCT02308566 Phase 4
7 Influence of the Concentration of the Local Anesthetic Ropivacaine on the Quality of a Ultrasound Guided Intermediate Cervical Block. Completed NCT01759940 Phase 4 ropivacaine 0,375%;ropivacaine 0,75%
8 Assess the Penumbra System in the Treatment of Acute Stroke Active, not recruiting NCT01429350 Phase 4 intravenous (IV) recombinant human tissue plasminogen activator (rtPA)
9 The Impact of NBP on the Collateral Circulation in ICA/M1 Occlusion Enrolling by invitation NCT02594995 Phase 4 NBP
10 Thrombectomy Under Reopro Versus Alteplase to Treat Stoke Terminated NCT02016547 Phase 4 alteplase 0.9mg/kg (10% by IV bolus following by 90% by 1 hour IV drip)
11 Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion Unknown status NCT00336596 Phase 3
12 The Carotid and Middle Cerebral Artery Occlusion Surgery Study Recruiting NCT01758614 Phase 3 Aspirin;Clopidogrel
13 A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVI Recruiting NCT02989558 Phase 3 Ticagrelor plus ASA;Clopidogrel plus ASA
14 Basilar Artery International Cooperation Study Recruiting NCT01717755 Phase 3
15 Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy Not yet recruiting NCT03163459 Phase 2, Phase 3 selective brain cooling by cold saline perfusion
16 Carotid Occlusion Surgery Study Terminated NCT00029146 Phase 3 best medical therapy
17 Interventional Management of Stroke (IMS) III Trial Terminated NCT00359424 Phase 3 IV rt-PA alone
18 Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial Withdrawn NCT00293735 Phase 2, Phase 3 labetalol (seizure prevention);MgSO4 (seizure prevention)
19 Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion Completed NCT00777140 Phase 2 Deferoxamine
20 Safety and Feasibility of Argatroban, Tissue Plasminogen Activator and Intra-arterial Therapy in Stroke Completed NCT02448069 Phase 2 Argatroban
21 Multi-modality MRI Study on Effect to Collateral Circulation and Blood Perfusion of Acute Cerebral Infarction by Human Urinary Kallidinogenase Completed NCT02259738 Phase 2 Human Urinary Kallidinogenase;Shuxuening injection
22 Role of Ginkgo Biloba Extract in IUGR Completed NCT02425436 Phase 2 Ginkgo Biloba Extract
23 Mechanical Recanalization With Flow Restoration in Acute Ischemic Stroke Completed NCT01210729 Phase 2
24 Ketamine for Thrombolysis in Acute Ischemic Stroke Recruiting NCT02258204 Phase 1, Phase 2 Ketamine;Placebo
25 Mild Hypothermia After Endovascular Treatment in Acute Ischemic Stroke Recruiting NCT02985060 Phase 2 Saline
26 Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma Recruiting NCT02861898 Phase 1, Phase 2 Intra-arterial Cetuximab;Intra-arterial Mannitol
27 Superiority of Rt-PA + Tenecteplase in Comparison With Rt-PA Only in Proximal Middle Cerebral Artery Occlusion Not yet recruiting NCT02338466 Phase 2 rt-PA;tenecteplase
28 Prevention for the Restenosis of Intracranial Artery Stent Implantation Treated With Herbal Medicine C117 Not yet recruiting NCT03008798 Phase 2 Herbal Medicine C-117;The Placebo of Herbal Medicine C-117
29 Intra-arterial Microplasmin Administration in Patients With Acute Intracranial Vertebrobasilar Artery Occlusion Terminated NCT00123266 Phase 2 Microplasmin
30 Microbubbles and Ultrasound in Stroke Trial: MUST Study Terminated NCT00222040 Phase 2 Levovist
31 Phase 2 Proof-of-Concept Study of the Safety and Efficacy of Alfimeprase to Rapidly Open Arteries and Restore Brain Function Following a Stroke Terminated NCT00499902 Phase 2 alfimeprase
32 Intra-arterial Magnesium Administration for Acute Stroke Terminated NCT01502761 Phase 1, Phase 2 Magnesium Sulfate
33 Safety and Efficacy of the Penumbra™ System in Acute Middle Cerebral Artery (MCA) Stroke Withdrawn NCT01133223 Phase 2 Recombinant tissue plasminogen activator
34 REperfusion With Cooling in CerebraL Acute IscheMia II Withdrawn NCT02411877 Phase 2
35 Reperfusion With Cooling in Cerebral Acute Ischemia II Withdrawn NCT01728649 Phase 2
36 Refractory Out-Of-Hospital Cardiac Arrest Treated With Mechanical CPR, Hypothermia, ECMO and Early Reperfusion Unknown status NCT01186614 Phase 1
37 Reperfusion With Cooling in Cerebral Acute Ischemia Completed NCT01585597 Phase 1
38 Stellate Ganglion Block Using Ultrasound Guidance For Treatment Of Post Clipping Cerebral Vasospasm Completed NCT02775318 Phase 1 Bupivacaine
39 Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke (REVISE-1) Recruiting NCT03210051 Phase 1
40 A Study to Evaluate the Effects of the Neuroflo Device in People Who Have Had a Stroke Withdrawn NCT00653536 Phase 1
41 Study of Aspirin and TPA in Acute Ischemic Stroke Withdrawn NCT00417898 Phase 1 Aspirin
42 Use of Hypothermia During Robotic Prostatectomy Unknown status NCT00915031
43 Rheolytic Thrombectomy For Adult Intraventricular Haemorrhage Unknown status NCT02394678
44 Preconditioning Shields Against Vascular Events in Surgery Unknown status NCT02097186
45 Restoration of Vision After Stroke Unknown status NCT02405143
46 Visualization of the Cerebral Arterial Circulation Using Contrast-Enhanced Transcranial Ultrasound in Code Stroke Patients Unknown status NCT00282841
47 TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique Unknown status NCT00294814
48 Neurothrombectomy France Completed NCT02880579
49 Impact of Interscalene Nerve Block on Cerebral Perfusion During Surgery in the Beachchair Position Completed NCT01983618
50 Aneurysms and Carotid Artery Block in Newborns Completed NCT00646672

Search NIH Clinical Center for Cerebral Artery Occlusion

Genetic Tests for Cerebral Artery Occlusion

Anatomical Context for Cerebral Artery Occlusion

MalaCards organs/tissues related to Cerebral Artery Occlusion:

39
Brain, Endothelial, Cortex, Bone, Bone Marrow, Retina, Thalamus

Publications for Cerebral Artery Occlusion

Articles related to Cerebral Artery Occlusion:

(show top 50) (show all 664)
id Title Authors Year
1
Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats. ( 28518065 )
2017
2
Hyperglycemia decreases preoxiredoxin-2 expression in a middle cerebral artery occlusion model. ( 28747974 )
2017
3
The Pyk2/MCU pathway in the rat middle cerebral artery occlusion model of ischemic stroke. ( 28916471 )
2017
4
Hypothermia exerts early neuroprotective effects involving protein conjugation of SUMOa892/3 in a rat model of middle cerebral artery occlusion. ( 28713891 )
2017
5
Intravenous infusion of mesenchymal stem cells inhibits intracranial hemorrhage after recombinant tissue plasminogen activator therapy for transient middle cerebral artery occlusion in rats. ( 28059661 )
2017
6
Metabolite changes in the ipsilateral and contralateral cerebral hemispheres in rats with middle cerebral artery occlusion. ( 28761426 )
2017
7
Assessment of the Neuroprotective Effects of Arginine-Rich Protamine Peptides, Poly-Arginine Peptides (R12-Cyclic, R22) and Arginine-Tryptophan-Containing Peptides Following In Vitro Excitotoxicity and/or Permanent Middle Cerebral Artery Occlusion in Rats. ( 28523591 )
2017
8
Early Thrombectomy of a Proximal Middle Cerebral Artery Occlusion Leading to Complete Recovery with No Infarct. ( 28559829 )
2017
9
Effects of crenolanib, a non-selective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion. ( 28943249 )
2017
10
Successful Revascularization of Acute Middle Cerebral Artery Occlusion by Intravenous Thrombolysis While on Apixaban. ( 28615907 )
2017
11
MRI Mouse Brain Data of Ischemic Lesion after Transient Middle Cerebral Artery Occlusion. ( 28932191 )
2017
12
Transfusion of Polynitroxylated Pegylated Hemoglobin Stabilizes Pial Arterial Dilation and Decreases Infarct Volume After Transient Middle Cerebral Artery Occlusion. ( 28899897 )
2017
13
A Case of Acute Isolated Posterior Cerebral Artery Occlusion Successfully Treated with Endovascular Clot Aspiration. ( 28664028 )
2017
14
Subacute endovascular recanalization of symptomatic cerebral artery occlusion: a propensity score-matched analysis. ( 28899866 )
2017
15
Safe time duration for temporary middle cerebral artery occlusion in aneurysm surgery based on motor-evoked potential monitoring. ( 28584682 )
2017
16
Leptomeningeal collateral status predicts outcome after middle cerebral artery occlusion. ( 28905995 )
2017
17
Neuroprotective effect of lercanidipine in middle cerebral artery occlusion model of stroke in rats. ( 27794423 )
2017
18
The effect of exercise preconditioning on stroke outcome in ovariectomized mice with permanent middle cerebral artery occlusion. ( 28873322 )
2017
19
Spontaneous recanalization of atherosclerotic middle cerebral artery occlusion: Case report. ( 28682888 )
2017
20
Hyperglycemia reduces PP2A subunit B expression in a middle cerebral artery occlusion animal model. ( 28652527 )
2017
21
Clinical Manifestations of Isolated Chronic Middle Cerebral Artery Occlusion in Relation to Angiographic Features. ( 28893698 )
2017
22
Therapeutic effects of oral dimethyl fumarate on stroke induced by middle cerebral artery occlusion: An animal experimental study. ( 28506000 )
2017
23
Acute Cerebral Artery Occlusion by a Calcified Embolus with False Patency Sign on Computed Tomographic Angiography. ( 27789151 )
2017
24
The Carotid and Middle cerebral artery Occlusion Surgery Study (CMOSS): a study protocol for a randomised controlled trial. ( 27852286 )
2016
25
Tongxinluo reduces brain edema and inhibits post-ischemic inflammation after middle cerebral artery occlusion in rats. ( 26805468 )
2016
26
Hemodynamic changes in a rat parietal cortex after endothelin-1-induced middle cerebral artery occlusion monitored by optical coherence tomography. ( 27469083 )
2016
27
Clinical Outcome Predicted by Collaterals Depends on Technical Success of Mechanical Thrombectomy in Middle Cerebral Artery Occlusion. ( 27856113 )
2016
28
Neuroprotective Properties of a Macrolide Antibiotic in a Mouse Model of Middle Cerebral Artery Occlusion: Characterization of the Immunomodulatory Effects and Validation of the Efficacy of Intravenous Administration. ( 27392039 )
2016
29
A Comparative Study of Variables Influencing Ischemic Injury in the Longa and Koizumi Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in Mice. ( 26870954 )
2016
30
A modification of intraluminal middle cerebral artery occlusion/reperfusion model for ischemic stroke with laser Doppler flowmetry guidance in mice. ( 27843320 )
2016
31
The temporal evolution of diffusional kurtosis imaging in an experimental middle cerebral artery occlusion (MCAO) model. ( 27125873 )
2016
32
Cerebral Hemodynamics and Vascular Reactivity in Mild and Severe Ischemic Rodent Middle Cerebral Artery Occlusion Stroke Models. ( 27358581 )
2016
33
ChAT-positive neurons participate in subventricular zone neurogenesis after middle cerebral artery occlusion in mice. ( 27609645 )
2016
34
Tirofiban combined with urokinase selective intra-arterial thrombolysis for the treatment of middle cerebral artery occlusion. ( 26998029 )
2016
35
Determinants of leptomeningeal collateral flow in stroke patients with a middle cerebral artery occlusion. ( 27438804 )
2016
36
Perfusion-Weighted MRI Parameters for Prediction of Early Progressive Infarction in Middle Cerebral Artery Occlusion. ( 27446514 )
2016
37
Multi-modal assessment of neurovascular coupling during cerebral ischaemia and reperfusion using remote middle cerebral artery occlusion. ( 27629101 )
2016
38
Ischemic brain injury decreases dynamin-like protein 1 expression in a middle cerebral artery occlusion animal model and glutamate-exposed HT22 cells. ( 28053612 )
2016
39
Chronic methamphetamine exposure prior to middle cerebral artery occlusion increases infarct volume and worsens cognitive injury in Male mice. ( 27021292 )
2016
40
Neuroprotective efficacy of poly-arginine R18 and NA-1 (TAT-NR2B9c) peptides following transient middle cerebral artery occlusion in the rat. ( 27639457 )
2016
41
Middle Cerebral Artery Occlusion Model of Stroke in Rodents: A Step-by-Step Approach. ( 26958146 )
2016
42
Comparisons between Garcia, Modo, and Longa rodent stroke scales: Optimizing resource allocation in rat models of focal middle cerebral artery occlusion. ( 27084232 )
2016
43
Sex differences in astrocyte and microglia responses immediately following middle cerebral artery occlusion in adult mice. ( 27717807 )
2016
44
Optical inhibition of striatal neurons promotes focal neurogenesis and neurobehavioral recovery in mice after middle cerebral artery occlusion. ( 27055780 )
2016
45
Multiple cerebral artery occlusion due to non-bacterial thrombotic endocarditis: an autopsy case report. ( 26960272 )
2016
46
Is shorter transient middle cerebral artery occlusion (t-MCAO) duration better in stroke experiments on diabetic female Sprague Dawely rats? ( 27541599 )
2016
47
Transarterial regional hypothermia provides robust neuroprotection in a rat model of permanent middle cerebral artery occlusion with transient collateral hypoperfusion. ( 27663968 )
2016
48
Mechanical Thrombectomy for Acute Middle Cerebral Artery Occlusion Caused by a Giant, Thrombosed, Extracranial Internal Carotid Artery Aneurysm. ( 27868402 )
2016
49
Lack of functional P2X7 receptor aggravates brain edema development after middle cerebral artery occlusion. ( 27048203 )
2016
50
Acute Hyperglycemia Is Associated with Immediate Brain Swelling and Hemorrhagic Transformation After Middle Cerebral Artery Occlusion in Rats. ( 26463955 )
2016

Variations for Cerebral Artery Occlusion

Expression for Cerebral Artery Occlusion

Search GEO for disease gene expression data for Cerebral Artery Occlusion.

Pathways for Cerebral Artery Occlusion

Pathways related to Cerebral Artery Occlusion according to GeneCards Suite gene sharing:

(show all 15)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.18 BDNF CNTF GDNF IL16 NOS2 NOS3
2
Show member pathways
12.97 CNTF GDNF IL16 IL1RN NOS2
3
Show member pathways
12.15 IL1RN NOS2 NOS3
4 11.58 BDNF GDNF NOS2
5 11.37 NOS2 NOS3
6
Show member pathways
11.31 NOS2 NOS3
7
Show member pathways
11.13 NOS2 NOS3
8
Show member pathways
11.1 NOS2 NOS3
9 11.03 BDNF CNTF GDNF
10
Show member pathways
10.98 NOS2 NOS3
11 10.88 NOS2 NOS3
12 10.78 NOS2 NOS3
13
Show member pathways
10.56 NOS2 NOS3 ODC1
14 10.37 NOS2 NOS3
15 10.06 NOS2 NOS3

GO Terms for Cerebral Artery Occlusion

Cellular components related to Cerebral Artery Occlusion according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 ADAMTS1 BDNF CNTF GDNF IL16 IL1RN

Biological processes related to Cerebral Artery Occlusion according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron apoptotic process GO:0043524 9.5 BDNF CNTF GDNF
2 negative regulation of blood pressure GO:0045776 9.4 NOS2 NOS3
3 nitric oxide mediated signal transduction GO:0007263 9.37 NOS2 NOS3
4 nitric oxide biosynthetic process GO:0006809 9.26 NOS2 NOS3
5 positive regulation of guanylate cyclase activity GO:0031284 9.16 NOS2 NOS3
6 ovulation from ovarian follicle GO:0001542 8.96 ADAMTS1 NOS3
7 arginine catabolic process GO:0006527 8.62 NOS2 NOS3

Molecular functions related to Cerebral Artery Occlusion according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.58 CNTF IL16 IL1RN
2 growth factor activity GO:0008083 9.54 BDNF CNTF GDNF
3 flavin adenine dinucleotide binding GO:0050660 9.46 NOS2 NOS3
4 NADP binding GO:0050661 9.43 NOS2 NOS3
5 FMN binding GO:0010181 9.32 NOS2 NOS3
6 arginine binding GO:0034618 9.26 NOS2 NOS3
7 NADPH-hemoprotein reductase activity GO:0003958 9.16 NOS2 NOS3
8 tetrahydrobiopterin binding GO:0034617 8.96 NOS2 NOS3
9 nitric-oxide synthase activity GO:0004517 8.62 NOS2 NOS3

Sources for Cerebral Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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