MCID: CRB008
MIFTS: 43

Cerebral Atherosclerosis malady

Categories: Cardiovascular diseases

Aliases & Classifications for Cerebral Atherosclerosis

Aliases & Descriptions for Cerebral Atherosclerosis:

Name: Cerebral Atherosclerosis 12 52 14 69
Intracranial Arteriosclerosis 42 69

Classifications:



External Ids:

Disease Ontology 12 DOID:12720
ICD10 33 I67.2
ICD9CM 35 437.0
MeSH 42 D002537
NCIt 47 C34459
UMLS 69 C0007775

Summaries for Cerebral Atherosclerosis

MalaCards based summary : Cerebral Atherosclerosis, also known as intracranial arteriosclerosis, is related to intracranial arteriosclerosis and atherosclerosis. An important gene associated with Cerebral Atherosclerosis is MTHFR (Methylenetetrahydrofolate Reductase), and among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and Folate Metabolism. The drugs Aspirin and Ethanol have been mentioned in the context of this disorder. Affiliated tissues include brain, smooth muscle and heart, and related phenotypes are Increased LDL uptake and cardiovascular system

Wikipedia : 71 Cerebral atherosclerosis is a type of atherosclerosis where build-up of plaque in the blood vessels of... more...

Related Diseases for Cerebral Atherosclerosis

Diseases related to Cerebral Atherosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 75)
id Related Disease Score Top Affiliating Genes
1 intracranial arteriosclerosis 12.1
2 atherosclerosis 10.6
3 cerebritis 10.6
4 schistosomiasis 10.2 APOE MTHFR
5 kartagener syndrome 10.2 ACE MTHFR
6 bullous skin disease 10.2 ACE MTHFR
7 glaucoma 1, open angle, n 10.2 APOE MTHFR
8 lupus erythematosus panniculitis 10.2 ACE APOE
9 iron metabolism disease 10.1 ACE APOE
10 villous adenoma 10.1 ACE MTHFR
11 cetp-related hyperalphalipoproteinemia 10.1 ACE APOE
12 porencephaly 2 10.1 ACE APOE
13 asphyxia neonatorum 10.1 ACE APOE
14 alpha-2-plasmin inhibitor deficiency 10.1 ACE MTHFR
15 hypertrichosis of eyelid 10.1 ACE MTHFR
16 interstitial emphysema 10.1 ACE MTHFR
17 familial progressive cardiac conduction defect 10.1 APOA1 APOE
18 flat umbilicus familial 10.1 ACE RNF213
19 albinism, oculocutaneous, type v 10.1 APOA1 APOE
20 hyperchlorhidrosis, isolated 10.1 APOA1 APOE
21 bird fancier's lung 10.1 APOA1 APOE
22 skin squamous cell carcinoma 10.1 APOA1 APOE
23 vernal conjunctivitis 10.1 ACE MTHFR
24 chondrocalcinosis with early-onset osteoarthritis 10.1 APOA1 APOE
25 stone in bladder diverticulum 10.1 APOA1 APOE
26 primary pigmented nodular adrenocortical disease 10.1 APOA1 APOE
27 childhood type dermatomyositis 10.1 APOE MTHFR
28 von willebrand disease, platelet-type 10.1 APOA1 APOE
29 bleeding disorder, east texas type 10.1 APOA1 APOE
30 neuropathy, hereditary sensory, type ib 10.1 MTHFR RNF213
31 mannosidosis, beta 10.1 APOA1 APOE
32 neuropathy, hereditary sensory and autonomic, type ia 10.1 APOA1 APOE
33 limb ischemia 10.0 ACE APOE
34 hypertriglyceridemia 10.0 APOA1 APOE
35 dyserythropoietic anemia, congenital, type ii 10.0 APOA1 APOE
36 cataract 5, multiple types 10.0 APOA1 APOE
37 neurofibroma of the heart 10.0 APOE MTHFR
38 acute apical periodontitis 10.0 APOA1 APOE
39 diabetic encephalopathy 10.0 ACE APOE
40 intra-abdominal lymph node mast cell malignancy 10.0 ACE APOE MTHFR
41 contagious pustular dermatitis 10.0 ACE APOE MTHFR
42 syringocystadenoma papilliferum 10.0 APOE RPSA
43 choroid plexus cancer 10.0 RNF213 RPSA
44 budd-chiari syndrome 10.0 ACE APOE MTHFR
45 xanthogranulomatous pyelonephritis 10.0 ACE APOE MTHFR
46 posterior uveal melanoma 10.0 APOA1 MTHFR
47 joint disorders 9.9 ACE APOA1 APOE
48 gait apraxia 9.9 ACE APOA1 APOE
49 optic nerve neoplasm 9.9 ACE APOA1 APOE
50 lipomatosis 9.9 ACE APOA1 APOE

Comorbidity relations with Cerebral Atherosclerosis via Phenotypic Disease Network (PDN): (show all 41)


Active Peptic Ulcer Disease Acute Cystitis
Alzheimer Disease Basilar Artery Insufficiency
Benign Essential Hypertension Borderline Personality Disorder
Bronchitis Bronchopneumonia
Cerebral Degeneration Cerebrovascular Disease
Chronic Kidney Failure Chronic Myocardial Ischemia
Decubitus Ulcer Deficiency Anemia
Encephalopathy Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation
Familial Atrial Fibrillation Generalized Atherosclerosis
Heart Disease Hypertension, Essential
Hypertensive Encephalopathy Hypoglycemia
Hypothyroidism Intracranial Embolism
Intracranial Thrombosis Iron Deficiency Anemia
Ischemic Heart Disease Left Ventricular Outflow Tract Obstruction
Malignant Essential Hypertension Osteoporosis
Parkinson Disease, Late-Onset Peripheral Vascular Disease
Protein-Energy Malnutrition Pseudobulbar Palsy
Schizophreniform Disorder Sinoatrial Node Disease
Status Epilepticus Swallowing Disorders
Transient Cerebral Ischemia Vascular Dementia
Vertebral Artery Insufficiency

Graphical network of the top 20 diseases related to Cerebral Atherosclerosis:



Diseases related to Cerebral Atherosclerosis

Symptoms & Phenotypes for Cerebral Atherosclerosis

GenomeRNAi Phenotypes related to Cerebral Atherosclerosis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased LDL uptake GR00340-A-1 8.62 APOA1 APOE

MGI Mouse Phenotypes related to Cerebral Atherosclerosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.35 ACE APOA1 APOE RNF213 RPSA
2 endocrine/exocrine gland MP:0005379 9.02 ACE APOA1 APOE RNF213 RPSA

Drugs & Therapeutics for Cerebral Atherosclerosis

Drugs for Cerebral Atherosclerosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 249)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
2
Ethanol Approved Phase 4 64-17-5 702
3
Cilostazol Approved Phase 4 73963-72-1 2754
4
Probucol Approved Phase 4 23288-49-5 4912
5
Amlodipine Approved Phase 4 88150-42-9 2162
6
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
7
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
8
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
9
Ezetimibe Approved Phase 4,Phase 3 163222-33-1 150311
10
Valsartan Approved, Investigational Phase 4,Phase 2 137862-53-4 60846
11
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
12
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
13
Metformin Approved Phase 4,Phase 3 657-24-9 14219 4091
14
Exenatide Approved, Investigational Phase 4 141758-74-9 15991534
15
Losartan Approved Phase 4 114798-26-4 3961
16
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3,Phase 2 120202-66-6, 113665-84-2 60606
17
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
18
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2 59-67-6 938
19
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3,Phase 2 98-92-0 936
20
Ginseng Approved, Nutraceutical Phase 4 50647-08-0
21 Anticholesteremic Agents Phase 4,Phase 3,Phase 2
22 Antimetabolites Phase 4,Phase 3,Phase 2
23 Hypolipidemic Agents Phase 4,Phase 3,Phase 2
24 Lipid Regulating Agents Phase 4,Phase 3,Phase 2
25 Protective Agents Phase 4,Phase 2,Phase 3
26 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
27 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 3,Phase 2
28 Micronutrients Phase 4,Phase 3,Phase 2
29 Trace Elements Phase 4,Phase 3,Phase 2
30 Vitamins Phase 4,Phase 3,Phase 2
31 Fluorides Phase 4,Phase 2
32 Anti-Asthmatic Agents Phase 4
33 Antioxidants Phase 4,Phase 2,Phase 3
34 Autonomic Agents Phase 4,Phase 2
35 Bronchodilator Agents Phase 4
36 Fibrinolytic Agents Phase 4,Phase 3
37 Neuroprotective Agents Phase 4,Phase 2
38 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
39 Phosphodiesterase 3 Inhibitors Phase 4
40 Phosphodiesterase Inhibitors Phase 4
41 Platelet Aggregation Inhibitors Phase 4,Phase 3
42 Respiratory System Agents Phase 4
43 Vasodilator Agents Phase 4,Phase 3,Phase 2
44
Angiotensin II Phase 4,Phase 2 68521-88-0, 11128-99-7 65143 172198
45 Angiotensin II Type 1 Receptor Blockers Phase 4,Phase 2
46 Angiotensin Receptor Antagonists Phase 4,Phase 2
47 Angiotensinogen Phase 4,Phase 2
48 Antihypertensive Agents Phase 4,Phase 3,Phase 2
49 calcium channel blockers Phase 4,Phase 2
50 Calcium, Dietary Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 275)
id Name Status NCT ID Phase
1 Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia Unknown status NCT00247533 Phase 4
2 Early Warning and Optimization Strategy in Carotid Endarterectomy Unknown status NCT01210937 Phase 4
3 Study of Cilostazol and Probucol Alone and in Combination on Atherosclerosis Related Biomarker---atherosclerosis Cerebral Infarction Patient as Study Subject Completed NCT00823875 Phase 4
4 Trial Comparing Metabolic Effects of Telmisartan and Amlodipine on Hypertensive Patients With Obesity and Diabetes Completed NCT00847262 Phase 4
5 Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II Completed NCT00130039 Phase 4
6 Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial Completed NCT00110448 Phase 4
7 Atorvastatin in Acute Stroke Treatment Completed NCT02225834 Phase 4
8 Resistance to Aspirin and/or Clopidogrel Among Patients With PAD. Completed NCT00262561 Phase 4
9 Platelet Hyperreactivity to Aspirin and Stroke Completed NCT00766896 Phase 4
10 Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients Completed NCT00449410 Phase 4
11 Emboshield® and Xact® Post Approval Carotid Stent Trial (The EXACT Study) Completed NCT00287508 Phase 4
12 Thyroid Hormone Replacement for Subclinical Hypothyroidism Completed NCT01660126 Phase 4
13 The Effects of Renin Angiotensin System Blockage (RAS), Calcium Channel Blocker and Combined Drugs on TWEAK, PTX3 and FMD Levels in Diabetic Proteinuric Patients With Hypertension Completed NCT00921570 Phase 4
14 Effect of 5 Years of GH Replacement on Atherosclerosis Completed NCT00462475 Phase 4
15 Carotid Atherosclerosis Regression at Magnetic Resonance Assessment. Completed NCT00307307 Phase 4
16 The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT) Completed NCT01341730 Phase 4
17 Stop Atherosclerosis in Native Diabetics Study Completed NCT00147251 Phase 4
18 Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study Completed NCT00723307 Phase 4
19 Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Carotid Intima-media Thickness (CIMT) Completed NCT01203982 Phase 4
20 The Safety and Efficacy of Cilostazol in Ischemic Stroke Patients With Peripheral Arterial Disease (SPAD Study) Completed NCT01188824 Phase 4
21 Establish The Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets (ACTFAST) Completed NCT00442845 Phase 4
22 Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets Completed NCT00442325 Phase 4
23 Intensive Rosuvastatin Therapy on Cerebral Hemodynamics in Patients With Atherosclerotic Intracranial Arterial Stenosis Recruiting NCT02594800 Phase 4
24 Intensive Statin Treatment in Acute Ischemic Stroke Patients With INtracranial Atherosclerosis Recruiting NCT02458755 Phase 4
25 Preventive Effects of Ginseng Against Atherosclerosis Recruiting NCT02796664 Phase 4
26 Effect of Bydureon on Carotid Atherosclerosis Progression in Type 2 Diabetes Mellitus Recruiting NCT02162550 Phase 4
27 A Study to Evaluate the Efficacy and Safety of Rosuvastatin in the Treatment of the Carotid Atherosclerotic Plaques Recruiting NCT02532309 Phase 4
28 Sleep Disordered Breathing in Transient Ischemic Attack (TIA)/Ischemic Stroke and Continuous Positive Airway Pressure (CPAP) Treatment Efficacy Active, not recruiting NCT01097967 Phase 4
29 Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication Active, not recruiting NCT00715273 Phase 4
30 Modulation of Monocyte Activation by Atorvastatin in HIV Infection Active, not recruiting NCT01263938 Phase 4
31 Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging Enrolling by invitation NCT02114697 Phase 4
32 Resuvastatin Treatment for Symptomatic Middle Cerebral Artery Stenosis Based on High-resolution Magnetic Resonance Imaging Not yet recruiting NCT02041117 Phase 4
33 Evaluate the Effect of Exenatide Treatment on Coronary Artery Endothelial Function Not yet recruiting NCT02584075 Phase 4
34 Strategy for Adequate Blood Pressure Lowering in the Patients With Intracranial Atherosclerosis Terminated NCT01104311 Phase 4
35 Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis Terminated NCT00805311 Phase 4
36 Carotid Plaque Regression With Statin Treatment Assessed by High Field Magnetic Resonance Imaging (MRI) Withdrawn NCT00388843 Phase 4
37 Effect Study of Modified Transoesophageal Echocardiography on Cerebral Embolization After Cardiothoracic Surgery Completed NCT01310608 Phase 3
38 EVA3S: Endarterectomy Versus Angioplasty in Patients With Severe Symptomatic Carotid Stenosis Completed NCT00190398 Phase 3
39 Cholesterol-Lowering Atherosclerosis Study (CLAS) Completed NCT00000599 Phase 3
40 Polypill Effects on Sub Clinical Atherosclerosis (PESCA) Trial Completed NCT01326676 Phase 3
41 Rosiglitazone Versus a Sulfonylurea On Progression Of Atherosclerosis In Patients With Heart Disease And Type 2 Diabetes Completed NCT00116831 Phase 3
42 Drug-eluting Balloon in Bifurcations Trial Completed NCT00857441 Phase 2, Phase 3
43 Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome Completed NCT02778776 Phase 3
44 Carotid Intima-media Thickness in Japan Statin Treatment Against Recurrent Stroke(J-STARS Echo) Completed NCT00361530 Phase 3
45 Effects of Lutein Supplementation on Subclinical Atherosclerosis Completed NCT01534533 Phase 2, Phase 3
46 Japan Statin Treatment Against Recurrent Stroke (J-STARS) Completed NCT00221104 Phase 3
47 Atherosclerosis Monitoring and Atherogenicity Reduction Study Completed NCT01734707 Phase 3
48 Specific Lp(a) Apheresis for Regression of Coronary and Carotid Atherosclerosis Completed NCT02133807 Phase 3
49 Women's Isoflavone Soy Health (WISH) Trial Completed NCT00118846 Phase 2, Phase 3
50 Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737) Completed NCT00526474 Phase 3

Search NIH Clinical Center for Cerebral Atherosclerosis

Cochrane evidence based reviews: intracranial arteriosclerosis

Genetic Tests for Cerebral Atherosclerosis

Anatomical Context for Cerebral Atherosclerosis

MalaCards organs/tissues related to Cerebral Atherosclerosis:

39
Brain, Smooth Muscle, Heart, Endothelial, Globus Pallidus

Publications for Cerebral Atherosclerosis

Articles related to Cerebral Atherosclerosis:

(show top 50) (show all 130)
id Title Authors Year
1
Value of higher-resolution MRI in assessing middle cerebral atherosclerosis and predicting capsular warning syndrome. ( 27080075 )
2016
2
Location of cerebral atherosclerosis: Why is there a difference between East and West? ( 27145795 )
2016
3
Intake of antioxidants and B vitamins is inversely associated with ischemic stroke and cerebral atherosclerosis. ( 27698959 )
2016
4
A pathological perspective on the natural history of cerebral atherosclerosis. ( 25854637 )
2015
5
Letter by Tsuda regarding article, "Serum alkaline phosphatase and phosphate in cerebral atherosclerosis and functional outcomes after cerebral infarction". ( 24448990 )
2014
6
Response to letter regarding article, "Serum alkaline phosphatase and phosphate in cerebral atherosclerosis and functional outcomes after cerebral infarction". ( 24448989 )
2014
7
Susceptibility vessel signs on T2*-weighted gradient echo images in patients with cerebral atherosclerosis. ( 25231582 )
2014
8
Different impact of hyperhomocysteinemia on cerebral small vessel ischemia and cervico-cerebral atherosclerosis in non-stroke individuals. ( 23218488 )
2013
9
Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction. ( 23686972 )
2013
10
Elevated AI^42 in aged, non-demented individuals with cerebral atherosclerosis. ( 23919773 )
2013
11
Cerebral atherosclerosis is associated with cystic infarcts and microinfarcts but not Alzheimer pathologic changes. ( 23887837 )
2013
12
Relationship between Cerebral Atherosclerosis and Leukoaraiosis in Aged Patients: Results from DSA. ( 24033698 )
2013
13
Serum alkaline phosphatase and phosphate in cerebral atherosclerosis and functional outcomes after cerebral infarction. ( 24021686 )
2013
14
The association between cerebral atherosclerosis and arterial stiffness in acute ischemic stroke. ( 21974846 )
2011
15
Increases in cerebral atherosclerosis according to CHADS2 scores in patients with stroke with nonvalvular atrial fibrillation. ( 21350200 )
2011
16
Plasma total homocysteine and the methylenetetrahydrofolate reductase 677C>T polymorphism do not contribute to the distribution of cervico-cerebral atherosclerosis in ischaemic stroke patients. ( 20825473 )
2011
17
Gender differences in risk factors for intracranial cerebral atherosclerosis among asymptomatic subjects. ( 21497768 )
2011
18
Cerebral atherosclerosis causes neurodegenerative diseases. ( 20037498 )
2010
19
Endothelial function in lacunar infarction: a comparison of lacunar infarction, cerebral atherosclerosis and control group. ( 19556769 )
2009
20
Intracranial angioplasty and stenting for cerebral atherosclerosis: a position statement of the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, and the American Society of Neuroradiology. ( 19560016 )
2009
21
Large vessel cerebral atherosclerosis is not in direct association with neuropathological lesions of Alzheimer's disease. ( 19521084 )
2009
22
Classic risk factors for atherosclerosis are not major determinants for location of extracranial or intracranial cerebral atherosclerosis. ( 19169042 )
2009
23
Risk factors of intracranial cerebral atherosclerosis among asymptomatics. ( 17690548 )
2007
24
Correlation of coronary and cerebral atherosclerosis: difference between extracranial and intracranial arteries. ( 16340186 )
2006
25
Intracranial angioplasty and stenting for cerebral atherosclerosis: new treatments for stroke are needed! ( 16622698 )
2006
26
Intracranial angioplasty & stenting for cerebral atherosclerosis: a position statement of the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, and the American Society of Neuroradiology. ( 16221663 )
2005
27
Intracranial angioplasty & stenting for cerebral atherosclerosis: a position statement of the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, and the American Society of Neuroradiology. ( 16223717 )
2005
28
Intracranial angioplasty and stent placement for cerebral atherosclerosis. ( 15101521 )
2004
29
Cerebral atherosclerosis and mild Alzheimer's disease. ( 12855821 )
2003
30
Cerebral atherosclerosis and oxidative stress in Alzheimer's disease. ( 14757939 )
2003
31
Cerebral atherosclerosis as predictor of stroke and mortality in representative elderly population. ( 11779914 )
2002
32
Cerebral atherosclerosis and coronary calcification. ( 12364716 )
2002
33
Cerebral atherosclerosis causes neurogenic hypertension. ( 11988586 )
2002
34
Cerebral atherosclerosis occurs spontaneously in homozygous WHHL rabbits. ( 11368997 )
2001
35
Early lesions of cerebral atherosclerosis from induced hypertension in Watanabe heritable hyperlipidemic rabbits. ( 11193506 )
2000
36
The influence of the degree of cerebral atherosclerosis on the changes in hemostatic system in patients with ischemic brain disease and atherosclerotic encephalopathy. ( 10645149 )
1999
37
Relation of plasma homocyst(e)ine to cerebral infarction and cerebral atherosclerosis. ( 9836754 )
1998
38
Cerebral atherosclerosis in Parkinsonian patients. ( 18591095 )
1998
39
The lipoprotein profile of young adults with cerebral atherosclerosis. ( 9031424 )
1996
40
Granule-laden perivascular cells observed in rabbits with experimental cerebral atherosclerosis. ( 8619506 )
1996
41
Race and sex differences in the distribution of cerebral atherosclerosis. ( 8898801 )
1996
42
Association between deletion polymorphism of the angiotensin-converting enzyme gene and cerebral atherosclerosis. ( 8704045 )
1996
43
Enhancement of the intracranial arterial wall at MR imaging: relationship to cerebral atherosclerosis. ( 7824729 )
1995
44
Pathology of cerebral atherosclerosis. Influence of age, race, and gender. ( 8249014 )
1993
45
Pattern of cerebral atherosclerosis in Hong Kong Chinese. Severity in intracranial and extracranial vessels. ( 8506547 )
1993
46
The effects of hypertension on cerebral atherosclerosis in the cynomolgus monkey. ( 8342199 )
1993
47
Experimental cerebral atherosclerosis in the rabbit. Scanning electron microscopic study of the initial lesion site. ( 1754505 )
1991
48
Relative protection from cerebral atherosclerosis of young patients with homozygous familial hypercholesterolemia. ( 1799396 )
1991
49
Investigation of the vertebral artery in cerebral atherosclerosis. ( 1864388 )
1991
50
Hypertension, cerebral vascular changes and stroke in Ghana: cerebral atherosclerosis and stroke. ( 2606028 )
1989

Variations for Cerebral Atherosclerosis

Expression for Cerebral Atherosclerosis

Search GEO for disease gene expression data for Cerebral Atherosclerosis.

Pathways for Cerebral Atherosclerosis

GO Terms for Cerebral Atherosclerosis

Cellular components related to Cerebral Atherosclerosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular vesicle GO:1903561 9.4 APOA1 APOE
2 high-density lipoprotein particle GO:0034364 9.37 APOA1 APOE
3 very-low-density lipoprotein particle GO:0034361 9.32 APOA1 APOE
4 endocytic vesicle lumen GO:0071682 9.26 APOA1 APOE
5 low-density lipoprotein particle GO:0034362 9.16 APOA1 APOE
6 chylomicron GO:0042627 8.96 APOA1 APOE
7 intermediate-density lipoprotein particle GO:0034363 8.62 APOA1 APOE

Biological processes related to Cerebral Atherosclerosis according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 cholesterol metabolic process GO:0008203 9.58 APOA1 APOE
2 negative regulation of inflammatory response GO:0050728 9.58 APOA1 APOE
3 cholesterol homeostasis GO:0042632 9.57 APOA1 APOE
4 retinoid metabolic process GO:0001523 9.56 APOA1 APOE
5 lipoprotein metabolic process GO:0042157 9.55 APOA1 APOE
6 triglyceride homeostasis GO:0070328 9.54 APOA1 APOE
7 triglyceride catabolic process GO:0019433 9.52 APOA1 APOE
8 cholesterol efflux GO:0033344 9.51 APOA1 APOE
9 reverse cholesterol transport GO:0043691 9.49 APOA1 APOE
10 high-density lipoprotein particle remodeling GO:0034375 9.48 APOA1 APOE
11 high-density lipoprotein particle assembly GO:0034380 9.46 APOA1 APOE
12 phospholipid efflux GO:0033700 9.43 APOA1 APOE
13 lipoprotein biosynthetic process GO:0042158 9.4 APOA1 APOE
14 chylomicron assembly GO:0034378 9.37 APOA1 APOE
15 positive regulation of cholesterol esterification GO:0010873 9.32 APOA1 APOE
16 chylomicron remodeling GO:0034371 9.26 APOA1 APOE
17 high-density lipoprotein particle clearance GO:0034384 9.16 APOA1 APOE
18 neuron projection regeneration GO:0031102 8.96 APOA1 APOE
19 regulation of Cdc42 protein signal transduction GO:0032489 8.62 APOA1 APOE

Molecular functions related to Cerebral Atherosclerosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 phospholipid binding GO:0005543 9.4 APOA1 APOE
2 cholesterol binding GO:0015485 9.37 APOA1 APOE
3 beta-amyloid binding GO:0001540 9.32 APOA1 APOE
4 lipid transporter activity GO:0005319 9.26 APOA1 APOE
5 cholesterol transporter activity GO:0017127 9.16 APOA1 APOE
6 lipoprotein particle binding GO:0071813 8.96 APOA1 APOE
7 phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 8.62 APOA1 APOE

Sources for Cerebral Atherosclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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