MCID: CRB094
MIFTS: 19

Cerebral Cavernous Malformations 3 malady

Summaries for Cerebral Cavernous Malformations 3

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46OMIM, 32MalaCards
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MalaCards: Cerebral Cavernous Malformations 3 is related to cerebritis and familial cerebral cavernous malformation 3. An important gene associated with Cerebral Cavernous Malformations 3 is PDCD10 (programmed cell death 10), and among its related pathways are E2F mediated regulation of DNA replication and Platelet sensitization by LDL. The compounds salubrinal and calyculin a have been mentioned in the context of this disorder.

Description from OMIM:46 603285

Aliases & Classifications for Cerebral Cavernous Malformations 3

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46OMIM, 60UMLS
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Aliases & Descriptions:

cerebral cavernous malformations 3 46 60


Related Diseases for Cerebral Cavernous Malformations 3

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Cerebral Cavernous Malformations 3:



Diseases related to cerebral cavernous malformations 3

Clinical Features for Cerebral Cavernous Malformations 3

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46OMIM
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Clinical features from OMIM:

603285

Drugs & Therapeutics for Cerebral Cavernous Malformations 3

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Cerebral Cavernous Malformations 3

Drug clinical trials:

Search ClinicalTrials for Cerebral Cavernous Malformations 3

Search NIH Clinical Center for Cerebral Cavernous Malformations 3

Search CenterWatch for Cerebral Cavernous Malformations 3

Genetic Tests for Cerebral Cavernous Malformations 3

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Anatomical Context for Cerebral Cavernous Malformations 3

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Animal Models for Cerebral Cavernous Malformations 3 or affiliated genes

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Publications for Cerebral Cavernous Malformations 3

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Genetic Variations for Cerebral Cavernous Malformations 3

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Expression for genes affiliated with Cerebral Cavernous Malformations 3

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cerebral Cavernous Malformations 3

Search GEO for disease gene expression data for Cerebral Cavernous Malformations 3.

Pathways for genes affiliated with Cerebral Cavernous Malformations 3

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53Reactome, 12EMD Millipore, 37NCBI BioSystems Database, 51QIAGEN, 29KEGG
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Compounds for genes affiliated with Cerebral Cavernous Malformations 3

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59Tocris Bioscience, 44Novoseek, 11DrugBank
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Compounds related to Cerebral Cavernous Malformations 3 according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1salubrinal5910.2PPP2R2D, PPP2R3B, PPP2CB
2calyculin a44 59 1112.0MSN, PPP2CB, PPP2R3B, PPP2R2D
3fk 506599.9PPP2R3B, PPP2CB, PPP2R2D

GO Terms for genes affiliated with Cerebral Cavernous Malformations 3

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16Gene Ontology
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Cellular components related to Cerebral Cavernous Malformations 3 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein phosphatase type 2A complexGO:0001599.7STRN4, PPP2CB, PPP2R3B, PPP2R2D, PPP2R5B
2cytoplasmGO:0057379.6MOB4, PPP2R5B, PPP2R2D, PPFIA3, STRN4, STRIP2

Molecular functions related to Cerebral Cavernous Malformations 3 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein phosphatase type 2A regulator activityGO:0086019.9IGBP1, PPP2R3B, PPP2R2D, PPP2R5B
2protein bindingGO:0055159.1PPP2CB, PPFIA3, PPP2R3B, PPP2R5B, PDCD10, MOB4

Products for genes affiliated with Cerebral Cavernous Malformations 3

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cerebral Cavernous Malformations 3

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet