MCID: CRB090
MIFTS: 43

Cerebral Hypoxia malady

Neuronal diseases category

Summaries for Cerebral Hypoxia

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NINDS:42 Cerebral hypoxia refers to a condition in which there is a decrease of oxygen supply to the brain even though there is adequate blood flow. Drowning, strangling, choking, suffocation, cardiac arrest, head trauma, carbon monoxide poisoning, and complications of general anesthesia can create conditions that can lead to cerebral hypoxia. Symptoms of mild cerebral hypoxia include inattentiveness, poor judgment, memory loss, and a decrease in motor coordination. Brain cells are extremely sensitive to oxygen deprivation and can begin to die within five minutes after oxygen supply has been cut off. When hypoxia lasts for longer periods of time, it can cause coma, seizures, and even brain death.

MalaCards based summary: Cerebral Hypoxia, also known as brain hypoxia, is related to ischemia and brain ischemia. An important gene associated with Cerebral Hypoxia is CASP9 (caspase 9, apoptosis-related cysteine peptidase), and among its related pathways are Amyotrophic lateral sclerosis (ALS) and p75(NTR)-mediated signaling. The compounds sulindac sulfide and cd 437 have been mentioned in the context of this disorder. Affiliated tissues include brain, spleen and cortex, and related mouse phenotypes are other and limbs/digits/tail.

Wikipedia:63 Cerebral hypoxia is a form of hypoxia (reduced supply of oxygen) specifically involving the brain; when... more...

Aliases & Classifications for Cerebral Hypoxia

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Sources:
42NINDS, 43Novoseek, 60UMLS
See all sources

Cerebral Hypoxia, Aliases & Descriptions:

Name: Cerebral Hypoxia 42 43
 
Brain Hypoxia 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Related Diseases for Cerebral Hypoxia

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Diseases related to Cerebral Hypoxia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 80)
idRelated DiseaseScoreTop Affiliating Genes
1ischemia31.1BMP7, PLAT, CASP3, CASP9, NOS1, CREB1
2brain ischemia30.1NOS1, APP, PLAT
3vascular disease29.9FOS, CASP3, CASP9, CREB1, NOS1
4hypoxia11.2
5cerebritis11.2
6neuronitis10.6
7brain injury10.5
8anoxia10.4
9traumatic brain injury10.4
10neurotic disorder10.3NOS1, CREB1
11ewing sarcoma10.3NOS1, CASP3
12coffin-lowry syndrome10.2FOS, CREB1
13myocardial infarction10.2PLAT, NOS1
14macular degeneration, age-related, 110.2PLAT
15prion disease10.2APP, CREB1, NOS1
16cerebral artery occlusion10.2
17hemorrhage, intracerebral10.2PLAT, APP
18eye disease10.1FOS, CASP3
19endometrial cancer10.1CASP9, CREB1, FOS
20thyroid cancer, anaplastic10.1BMP7, CASP3
21parkinson disease, late-onset10.1APP, NOS1, CASP9, CASP3
22huntington disease10.1NOS1, CREB1, APP, CASP3
23hyperglycemia10.1IGF1, CREB1, CASP3
24kidney disease10.1CASP3, FOS, BMP7
25mental retardation10.0CREB1, FOS, APP
26viral infectious disease10.0ITGAV, NOS1, CREB1, CASP9
27t-cell leukemia10.0FOS, CASP9, CREB1, CASP3
28factor v leiden thrombophilia10.0CREB1, PLAT, NOS1
29myeloid leukemia10.0FOS, CASP9, CREB1, CASP3
30sudden infant death syndrome10.0
31moyamoya disease10.0
32migraine10.0
33pulmonary edema10.0
34dementia10.0
35dystonia10.0
36focal dystonia10.0
37intracranial hypertension10.0
38lactic acidosis10.0
39laryngitis10.0
40wallerian degeneration10.0
41myoclonus10.0
42syncope10.0
43endotheliitis10.0
44retinoblastoma10.0FOS, CASP3, CASP9, CREB1
45toxic encephalopathy10.0APP, FOS, CASP3, CREB1
46amyotrophic lateral sclerosis 110.0CASP3, APP, NOS1, IGF1
47b-cell lymphomas10.0CASP9, ITGB1, CASP3
48alzheimer disease10.0CASP3, APP, NOS1, CREB1, CASP9
49down syndrome10.0APP, ITGB1, CREB1
50adenoma9.9ITGAV, IGF1, CREB1, NOS1

Graphical network of the top 20 diseases related to Cerebral Hypoxia:



Diseases related to cerebral hypoxia

Symptoms for Cerebral Hypoxia

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Drugs & Therapeutics for Cerebral Hypoxia

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Drug clinical trials:

Search ClinicalTrials for Cerebral Hypoxia

Search NIH Clinical Center for Cerebral Hypoxia

Genetic Tests for Cerebral Hypoxia

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Anatomical Context for Cerebral Hypoxia

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MalaCards organs/tissues related to Cerebral Hypoxia:

31
Brain, Spleen, Cortex, Lung, Monocytes, Endothelial

Animal Models for Cerebral Hypoxia or affiliated genes

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MGI Mouse Phenotypes related to Cerebral Hypoxia:

35 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.3NOS1, ITGB1, APP
2MP:00053718.2IGF1, FOS, ITGB1, BMP7
3MP:00053917.9FOS, ITGB1, BMP7, PLAT, CASP3, NOS1
4MP:00053777.8IGF1, FOS, ITGB1, BMP7, PLAT, CASP3
5MP:00107717.6IGF1, APP, FOS, ITGB1, BMP7, CASP3
6MP:00053817.6ITGB1, ITGAV, BMP7, PLAT, CASP3, NOS1
7MP:00053807.6FOS, ITGB1, ITGAV, BMP7, CASP9, CREB1
8MP:00053677.5IGF1, ITGB1, ITGAV, BMP7, CASP3, NOS1
9MP:00053887.5IGF1, ITGB1, BMP7, PLAT, CASP3, CASP9
10MP:00028737.4IGF1, APP, FOS, ITGB1, BMP7, CAMK4
11MP:00053827.3FOS, ITGB1, ITGAV, BMP7, PLAT, CASP3
12MP:00053907.0IGF1, FOS, ITGB1, BMP7, PLAT, CASP3
13MP:00053696.9IGF1, APP, ITGB1, ITGAV, PLAT, CASP3
14MP:00053866.8APP, FOS, ITGB1, ITGAV, PLAT, CASP3
15MP:00053796.7IGF1, FOS, ITGB1, ITGAV, BMP7, CASP3
16MP:00053896.7ITGB1, FOS, APP, IGF1, BMP7, PLAT
17MP:00053856.6IGF1, ITGB1, ITGAV, BMP7, PLAT, CASP3
18MP:00053976.6IGF1, FOS, ITGB1, ITGAV, PLAT, CASP3
19MP:00053766.2IGF1, APP, FOS, ITGB1, ITGAV, PLAT
20MP:00053846.0ITGB1, FOS, APP, IGF1, ITGAV, PLAT
21MP:00053875.9IGF1, APP, FOS, ITGB1, ITGAV, BMP7
22MP:00036315.6NOS1, IGF1, APP, FOS, ITGB1, ITGAV
23MP:00053785.6ITGAV, ITGB1, FOS, APP, IGF1, BMP7
24MP:00107685.6ITGAV, ITGB1, FOS, APP, IGF1, BMP7

Publications for Cerebral Hypoxia

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Articles related to Cerebral Hypoxia:

(show top 50)    (show all 236)
idTitleAuthorsYear
1
Cerebral hypoxia-ischemia increases toll-like receptor 2 and 4 expression in the hippocampus of neonatal rats. (25530127)
2014
2
Therapeutic benefits of delayed lithium administration in the neonatal rat after cerebral hypoxia-ischemia. (25211332)
2014
3
Targeted drug delivery to treat pain and cerebral hypoxia. (23343976)
2013
4
Cognitive decline in moyamoya: influence of chronic cerebral hypoxia, history of stroke, or comorbid conditions? (22171927)
2012
5
Experimental evidence of the potential use of erythropoietin by intranasal administration as a neuroprotective agent in cerebral hypoxia. (21756166)
2011
6
Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia. (19782128)
2010
7
Inhibition of integrin alphavbeta3 prevents urokinase plasminogen activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia. (19168722)
2009
8
Alternate pathways preserve tumor necrosis factor-alpha production after nuclear factor-kappaB inhibition in neonatal cerebral hypoxia-ischemia. (19628795)
2009
9
Mild cerebral hypoxia-ischemia produces a sub-acute transient inflammatory response that is less selective and prolonged after a substantial insult. (19631731)
2009
10
Enhancement of autophagic flux after neonatal cerebral hypoxia-ischemia and its region-specific relationship to apoptotic mechanisms. (19815706)
2009
11
"Therapeutic time window" duration decreases with increasing severity of cerebral hypoxia-ischaemia under normothermia and delayed hypothermia in newborn piglets. (17475224)
2007
12
Plasminogen activators contribute to impairment of hypercapnic and hypotensive cerebrovasodilation after cerebral hypoxia/ischemia in the newborn pig. (16141421)
2005
13
The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. (15592434)
2005
14
A novel role for an established player: anemia drug erythropoietin for the treatment of cerebral hypoxia/ischemia. (15294194)
2004
15
Extracellular superoxide concentration increases following cerebral hypoxia but does not affect cerebral blood flow. (15245758)
2004
16
Delayed postischemic hypothermia improves long-term behavioral outcome after cerebral hypoxia-ischemia in neonatal rats. (11861942)
2002
17
Caspase-3 activation after neonatal rat cerebral hypoxia-ischemia. (11275647)
2001
18
Detection and treatment of cerebral hypoxia key to avoiding intraoperative brain injuries. (12578096)
2000
19
Subcellular distribution of calcium and ultrastructural changes after cerebral hypoxia-ischemia in immature rats. (11154758)
2000
20
Impairment of mitochondrial respiration after cerebral hypoxia-ischemia in immature rats: relationship to activation of caspase-3 and neuronal injury. (11154759)
2000
21
Prevention of both T2- and diffusion-weighted increases in image intensity during cerebral hypoxia-ischemia in infant rats pretreated with dexamethasone. (10204774)
1999
22
Magnetic resonance imaging during cerebral hypoxia-ischemia: T2 increases in 2-week-old but not 4-week-old rats. (10022586)
1999
23
Cerebral hypoxia after cardiopulmonary resuscitation. (10073537)
1999
24
Metabolite changes in neonatal rat brain during and after cerebral hypoxia-ischemia: a magnetic resonance spectroscopic imaging study. (10195327)
1999
25
Effect of propentofylline on free radical generation during cerebral hypoxia in the newborn piglet. (9578400)
1998
26
Lipid free radical generation and brain cell membrane alteration following nitric oxide synthase inhibition during cerebral hypoxia in the newborn piglet. (9326283)
1997
27
Nuclear condensation and fragmentation following cerebral hypoxia-ischemia occurs more frequently in immature than older rats. (9089690)
1997
28
Neonatal cerebral hypoxia-ischemia: the effect of adenosine receptor antagonists. (9364488)
1997
29
Influence of age on the cerebral lesions in an immature rat model of cerebral hypoxia-ischemia: a light microscopic study. (9205806)
1997
30
Specific inhibition of apoptosis after cerebral hypoxia-ischaemia by moderate post-insult hypothermia. (8554576)
1995
31
DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat. (7614012)
1995
32
Syncope: a videometric analysis of 56 episodes of transient cerebral hypoxia. (8053660)
1994
33
Delayed-onset focal dystonia after diffuse cerebral hypoxia--two case reports. (8179837)
1993
34
Brain metabolism and blood flow in acute cerebral hypoxia studied by NMR spectroscopy and hydrogen clearance. (1550710)
1992
35
Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage. (1971436)
1990
36
Protective effect of KB-2796, a new calcium antagonist, in cerebral hypoxia and ischemia. (2241412)
1990
37
Cerebral hypoxia-ischemia in immature rats: methodological considerations. (3342854)
1988
38
Visual defects in children after cerebral hypoxia. (6525237)
1984
39
Early computed tomographic abnormalities following profound cerebral hypoxia. (6477220)
1984
40
The role of dilantin in the prevention of pulmonary edema associated with cerebral hypoxia. (7083868)
1982
41
Gray matter enhancement: a computerized tomographic sign of cerebral hypoxia. (7191063)
1980
42
Hyperventilation-induced cerebral hypoxia. (6774644)
1980
43
The morphologic consequences of cerebral hypoxia. (517287)
1979
44
Immediate restoration of central nervous system autonomic cardiopulmonary control: survival of "lethal" cerebral hypoxia by treatment with prostaglandin Bx. (401242)
1978
45
Effect of gamma-oxybutyric acid on the subcellular reaction to cerebral hypoxia [proceedings]. (885430)
1977
46
Histopathologic and ultrastructural study in infantile encephalopathy by obstetrical cerebral hypoxia. (987614)
1976
47
The CSF lactate-pyruvate ratio in cerebral hypoxia. (5638919)
1968
48
Cardiac factors in cerebral hypoxia. (14020142)
1963
49
Action of cerebral hypoxia on the pulmonary arterial pressure of the dog (14437309)
1960
50
Cerebral hypoxia: aetiology and treatment. (13293396)
1956

Variations for Cerebral Hypoxia

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Expression for genes affiliated with Cerebral Hypoxia

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Search GEO for disease gene expression data for Cerebral Hypoxia.

Pathways for genes affiliated with Cerebral Hypoxia

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Pathways related to Cerebral Hypoxia according to GeneCards Suite gene sharing:

(show top 50)    (show all 113)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Amyotrophic lateral sclerosis (ALS)36
9.5NOS1, CASP9, CASP3
2
Show member pathways
9.5APP, CASP3, CASP9
39.2APP, CAMK4, CREB1, NOS1
4
Show member pathways
Alzheimers Disease36
9.2NOS1, CASP9, CASP3, APP
59.1CAMK4, CASP9, CASP3, FOS
6
Show member pathways
Calcium Regulation in the Cardiac Cell36
9.1FOS, CAMK4, CREB1, NOS1
7
Show member pathways
9.1CREB1, CASP9, CASP3, FOS
89.1FOS, CASP3, CASP9, CREB1
9
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
9.1FOS, CASP3, CASP9, CREB1
109.1FOS, CASP3, CAMK4, CREB1
11
Show member pathways
DNA damage response36
8.9CREB1, CASP9, CASP3, IGF1
128.9PLAT, BMP7, IGF1
13
Show member pathways
8.9FOS, ITGB1, CASP3, CASP9
14
Show member pathways
FAS pathway and Stress induction of HSP regulation36
Apoptosis and survival FAS signaling cascades58
Caspase cascade in apoptosis36
8.9CASP9, CASP3, APP, IGF1
15
Show member pathways
Prolactin Signaling Pathway36
Development Prolactin receptor signaling58
Leptin signaling pathway36
8.9CREB1, CASP3, ITGB1, FOS
16
Show member pathways
Apoptosis Modulation and Signaling36
Apoptosis36
8.8IGF1, FOS, CASP3, CASP9
17
Show member pathways
8.8IGF1, FOS, CASP3, CAMK4
18
Show member pathways
8.8PLAT, CASP3, CASP9, CAMK4, CREB1
19
Show member pathways
8.7APP, FOS, CASP3, CASP9, CREB1
20
Show member pathways
8.7BMP7, ITGAV, ITGB1
21
Show member pathways
8.7FOS, BMP7, CAMK4, CREB1, NOS1
22
Show member pathways
Immune response BCR pathway58
Fc-epsilon receptor I signaling in mast cells36
8.6CREB1, CASP9, ITGAV, FOS
23
Show member pathways
Cytoskeleton remodeling FAK signaling58
Development Endothelin 1 EDNRA transactivation of EGFR58
8.6CREB1, ITGB1, FOS, IGF1
248.6IGF1, APP, CASP3, CASP9, CREB1
25
Show member pathways
8.5ITGB1, ITGAV, CASP3, CASP9
26
Show member pathways
8.4FOS, ITGB1, ITGAV, CASP9
27
Show member pathways
8.4APP, FOS, CASP3, CAMK4, CREB1, NOS1
28
Show member pathways
8.4ITGB1, ITGAV, BMP7, CASP3
29
Show member pathways
8.4IGF1, FOS, BMP7, CASP3, CASP9
30
Show member pathways
Transcription Receptor mediated HIF regulation58
Development CNTF receptor signaling58
Class IB PI3K non-lipid kinase events36
ErbB2/ErbB3 signaling events36
Development Growth hormone signaling via PI3K AKT and MAPK cascades58
Translation Regulation activity of EIF258
Regulation of lipid metabolism Insulin signaling generic cascades58
Transcription PPAR Pathway58
Cell adhesion PLAU signaling58
Translation Regulation activity of EIF4F58
8.4PLAT, ITGB1, FOS, IGF1
31
Show member pathways
Development EGFR signaling via PIP358
Development PDGF signaling via MAPK cascades58
Apoptosis and survival Anti apoptotic action of membrane bound ESR158
Signaling of Hepatocyte Growth Factor Receptor36
Development EGFR signaling via small GTPases58
Development Neurotrophin family signaling58
Apoptosis and survival NGF signaling pathway58
Apoptosis and survival Role of CDK5 in neuronal death and survival58
8.3FOS, ITGB1, CASP3, CASP9, CAMK4, CREB1
32
Show member pathways
Signal transduction PTEN pathway58
8.3IGF1, FOS, ITGB1, CASP3, CASP9
338.2CASP3, ITGAV, ITGB1, IGF1
34
Show member pathways
8.1FOS, BMP7, CASP3, CASP9, CAMK4, CREB1
35
Show member pathways
Development EDNRB signaling58
Development ACM2 and ACM4 activation of ERK58
Cell adhesion Integrin inside out signaling58
Development G Proteins mediated regulation MARK ERK signaling58
Signal transduction IP3 signaling58
Development Angiotensin signaling via PYK258
Development EPO induced MAPK pathway58
8.1FOS, ITGB1, ITGAV, CAMK4, CREB1
36
Show member pathways
Integrin-mediated cell adhesion36
Focal Adhesion36
8.1IGF1, FOS, ITGB1, ITGAV
37
Show member pathways
8.1ITGAV, ITGB1, FOS, IGF1
38
Show member pathways
8.0FOS, ITGB1, ITGAV, CASP3, CREB1
397.9CREB1, CASP9, ITGAV, ITGB1, IGF1
40
Show member pathways
7.8IGF1, APP, PLAT, CASP3, CASP9, CAMK4
41
Show member pathways
7.7IGF1, ITGB1, ITGAV, CASP9, CAMK4, CREB1
42
Show member pathways
7.5IGF1, ITGB1, ITGAV, BMP7, CAMK4, CREB1
437.4IGF1, FOS, ITGB1, ITGAV, CASP3, CASP9
44
Show member pathways
7.3IGF1, FOS, ITGB1, ITGAV, BMP7, CREB1
45
Show member pathways
7.3IGF1, APP, ITGB1, ITGAV, PLAT, NOS1
46
Show member pathways
7.1IGF1, FOS, ITGB1, ITGAV, BMP7, CAMK4
47
Show member pathways
6.7NOS1, FOS, ITGB1, ITGAV, BMP7, CASP3
48
Show member pathways
6.7IGF1, FOS, ITGB1, ITGAV, BMP7, CASP3
49
Show member pathways
6.7IGF1, FOS, ITGB1, ITGAV, BMP7, CASP3
50
Show member pathways
6.4IGF1, APP, FOS, ITGB1, ITGAV, BMP7

Compounds for genes affiliated with Cerebral Hypoxia

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Compounds related to Cerebral Hypoxia according to GeneCards Suite gene sharing:

(show top 50)    (show all 135)
idCompoundScoreTop Affiliating Genes
1sulindac sulfide439.8CASP9, APP, CASP3
2cd 437439.6FOS, CASP3, CASP9
315-deoxy-delta-12,14-prostaglandin j2439.5CASP9, FOS, CASP3, CREB1
4pdtc439.5FOS, CASP3, NOS1, CASP9
5ethidium bromide439.5CASP3, CASP9, PLAT
6s-nitroso-n-acetylpenicillamine439.4NOS1, CASP9, CASP3
76-hydroxydopamine439.4APP, CASP3, FOS, CREB1
8corticosterone43 59 2411.4NOS1, CREB1, FOS, APP
9egcg439.4CASP3, APP, CASP9, FOS
10carbachol43 28 1211.4CREB1, APP, FOS, NOS1
11thapsigargin43 5910.3CREB1, CASP9, CASP3, APP
12lactacystin439.3APP, NOS1, CASP9, CREB1, CASP3
135-hydroxytryptamine439.3CREB1, NOS1, APP, PLAT
14simvastatin43 49 59 28 24 1214.3CASP9, CASP3, APP, PLAT
15sp 60012543 5910.3CASP9, CASP3, ITGB1, FOS
163-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide439.2CASP3, CASP9, APP
17isoproterenol43 1210.2NOS1, CREB1, PLAT, APP
18retinoid439.2CREB1, CAMK4, CASP9, FOS
194-hydroxynonenal43 2410.2CASP9, APP, FOS, CREB1, CASP3
20chelerythrine439.2IGF1, FOS, CREB1
21curcumin439.1CASP9, APP, CREB1, CASP3, FOS
22butyrate439.1CREB1, CASP9, CASP3, FOS, APP
23pge2439.0BMP7, CASP9, CREB1, NOS1, FOS
24titanium439.0ITGAV, ITGB1, BMP7
25rapamycin438.9CREB1, CASP9, IGF1, CASP3, BMP7
26nmda43 289.9FOS, CASP9, CAMK4, CREB1, APP, NOS1
27ly294002438.8FOS, CREB1, CASP9, CASP3, IGF1
28h2o2438.8CASP9, CREB1, FOS, NOS1, CASP3, APP
29dopamine43 28 24 1211.7IGF1, NOS1, FOS, APP, CREB1
30glutamine438.7NOS1, CREB1, ITGB1, IGF1, APP
31gnrh438.6IGF1, CREB1, FOS, APP, PLAT
32glutamate438.6CREB1, NOS1, CASP9, FOS, APP, PLAT
33calcitriol43 59 24 1211.6BMP7, IGF1, FOS, ITGB1, CREB1
34cyclosporin a43 28 5910.5CASP9, PLAT, ITGB1, NOS1, APP, CASP3
35adenylate438.5NOS1, CREB1, PLAT, FOS, APP
36creatinine438.4APP, IGF1, NOS1, PLAT, BMP7
37pd 98,059438.4IGF1, FOS, CREB1, CASP9, CASP3, ITGB1
38wortmannin438.4ITGB1, CASP3, CASP9, IGF1, CREB1, FOS
39phosphatidylinositol438.3ITGB1, FOS, CREB1, IGF1, CASP9, CASP3
40cysteine438.2NOS1, CASP3, PLAT, APP, ITGB1, CREB1
41estrogen438.1IGF1, FOS, ITGB1, NOS1, BMP7, CREB1
42sb 20358043 599.1NOS1, CASP3, CASP9, ITGB1, FOS, IGF1
43genistein43 28 59 2 24 1213.1ITGB1, FOS, IGF1, CASP9, CASP3, CREB1
44actinomycin d438.0APP, CASP9, CASP3, PLAT, FOS, IGF1
45dexamethasone43 49 28 1210.6NOS1, BMP7, CASP9, CREB1, APP, IGF1
46tyrosine437.2BMP7, ITGAV, CAMK4, CREB1, ITGB1, FOS
47cycloheximide437.2CREB1, FOS, NOS1, IGF1, ITGB1, BMP7
48retinoic acid43 247.8NOS1, FOS, CASP9, CASP3, PLAT, BMP7
49vegf436.7CASP3, BMP7, ITGAV, FOS, ITGB1, APP
50serine436.5FOS, NOS1, CREB1, CAMK4, CASP9, IGF1

GO Terms for genes affiliated with Cerebral Hypoxia

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Cellular components related to Cerebral Hypoxia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1synapseGO:00452029.3APP, PLAT, NOS1
2integrin complexGO:00083059.0ITGAV, ITGB1
3cell surfaceGO:00099868.3PLAT, ITGAV, ITGB1, APP
4cytosolGO:00058298.1APP, FOS, CASP3, CASP9, CAMK4, NOS1
5extracellular vesicular exosomeGO:00700628.0CAMK4, PLAT, ITGAV, ITGB1, APP

Biological processes related to Cerebral Hypoxia according to GeneCards Suite gene sharing:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1glial cell apoptotic processGO:003434910.2CASP9, CASP3
2activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome cGO:000863510.1CASP3, CASP9
3platelet formationGO:003022010.1CASP9, CASP3
4positive regulation of osteoclast differentiationGO:00456729.9CREB1, FOS
5Type I pneumocyte differentiationGO:00605099.8CREB1, IGF1
6SMAD protein signal transductionGO:00603959.8BMP7, FOS
7fibroblast growth factor receptor signaling pathwayGO:00085439.8CASP9, CAMK4, CREB1
8neuron apoptotic processGO:00514029.8CASP3, APP
9epidermal growth factor receptor signaling pathwayGO:00071739.7CREB1, CAMK4, CASP9
10Fc-epsilon receptor signaling pathwayGO:00380959.6FOS, CASP9, CREB1
11dendrite developmentGO:00163589.6BMP7, APP
12neurotrophin TRK receptor signaling pathwayGO:00480119.6CASP3, CASP9, CAMK4, CREB1
13regulation of multicellular organism growthGO:00400149.5IGF1, APP
14phosphatidylinositol-mediated signalingGO:00480159.5CREB1, CASP9, IGF1
15negative regulation of neuron differentiationGO:00456659.5BMP7, ITGB1, APP
16branching morphogenesis of an epithelial tubeGO:00487549.4BMP7, IGF1
17positive regulation of apoptotic processGO:00430659.2ITGB1, BMP7, CASP3, CASP9
18innate immune responseGO:00450879.1APP, FOS, CASP9, CAMK4, CREB1
19extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.0CASP3, ITGAV, IGF1
20positive regulation of transcription, DNA-templatedGO:00458938.7IGF1, FOS, BMP7, CAMK4, CREB1
21negative regulation of extrinsic apoptotic signaling pathwayGO:020012378.7ITGAV, IGF1
22axon guidanceGO:00074118.7CREB1, BMP7, ITGAV, ITGB1
23extracellular matrix organizationGO:00301988.4APP, ITGB1, ITGAV, BMP7, CASP3
24positive regulation of transcription from RNA polymerase II promoterGO:00459448.3IGF1, APP, FOS, BMP7, CREB1, NOS1
25blood coagulationGO:00075967.7NOS1, PLAT, ITGAV, ITGB1, APP, IGF1

Molecular functions related to Cerebral Hypoxia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1virus receptor activityGO:00016189.1ITGAV, ITGB1
2protein bindingGO:00055155.2NOS1, IGF1, APP, FOS, ITGB1, ITGAV

Products for genes affiliated with Cerebral Hypoxia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Cerebral Hypoxia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet