MCID: CRB090
MIFTS: 49

Cerebral Hypoxia malady

Download this MalaCard

Summaries for Cerebral Hypoxia

About this section


Fully expand this MalaCard
NINDS:43 Cerebral hypoxia refers to a condition in which there is a decrease of oxygen supply to the brain even though there is adequate blood flow. Drowning, strangling, choking, suffocation, cardiac arrest, head trauma, carbon monoxide poisoning, and complications of general anesthesia can create conditions that can lead to cerebral hypoxia. Symptoms of mild cerebral hypoxia include inattentiveness, poor judgment, memory loss, and a decrease in motor coordination. Brain cells are extremely sensitive to oxygen deprivation and can begin to die within five minutes after oxygen supply has been cut off. When hypoxia lasts for longer periods of time, it can cause coma, seizures, and even brain death.

MalaCards based summary: Cerebral Hypoxia, also known as hypoxia, cerebral, is related to ischemia and memory impairment. An important gene associated with Cerebral Hypoxia is CASP9 (caspase 9, apoptosis-related cysteine peptidase), and among its related pathways are Amyotrophic lateral sclerosis (ALS) and p75(NTR)-mediated signaling. The compounds sulindac sulfide and cd 437 have been mentioned in the context of this disorder. Affiliated tissues include brain, spleen and cortex, and related mouse phenotypes are other and limbs/digits/tail.

Wikipedia:65 Cerebral hypoxia is a form of hypoxia (reduced supply of oxygen) specifically involving the brain; when... more...

Aliases & Classifications for Cerebral Hypoxia

About this section
Sources:
43NINDS, 44Novoseek, 62UMLS
See all sources

Cerebral Hypoxia, Aliases & Descriptions:

Name: Cerebral Hypoxia 43 44
 
Hypoxia, Cerebral 62


Related Diseases for Cerebral Hypoxia

About this section

Diseases related to Cerebral Hypoxia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 86)
idRelated DiseaseScoreTop Affiliating Genes
1ischemia31.1BMP7, PLAT, CASP3, CASP9, NOS1, CREB1
2memory impairment30.3APP, CREB1
3brain ischemia30.2NOS1, APP, PLAT
4vascular disease29.9FOS, CASP3, CASP9, CREB1, NOS1
5hypoxia11.2
6cerebritis11.2
7neuronitis10.6
8brain injury10.4
9anoxia10.4
10traumatic brain injury10.4
11bipolar disorder10.3NOS1, CREB1
12neuroepithelioma10.3NOS1, CASP3
13coffin-lowry syndrome10.3FOS, CREB1
14age related macular degeneration10.2PLAT
15myocardial infarction10.2PLAT, NOS1
16stroke, hemorrhagic10.2PLAT, APP
17prion disease10.2APP, CREB1, NOS1
18hemorrhage, intracerebral10.2PLAT, APP
19cerebral artery occlusion10.2
20spiradenoma10.2FOS, CASP3
21endometrial carcinoma10.1CASP9, CREB1, FOS
22thyroid cancer, anaplastic10.1BMP7, CASP3
23parkinson's disease10.1APP, NOS1, CASP9, CASP3
24huntington's disease10.1NOS1, CREB1, APP, CASP3
25hyperglycemia10.1IGF1, CREB1, CASP3
26primary hyperoxaluria10.1CASP3, FOS, BMP7
27mental retardation10.0CREB1, FOS, APP
28factor v leiden thrombophilia10.0CREB1, PLAT, NOS1
29viral infectious disease10.0ITGAV, NOS1, CREB1, CASP9
30t-cell leukemia10.0FOS, CASP9, CREB1, CASP3
31myeloid leukemia10.0FOS, CASP9, CREB1, CASP3
32hypertension10.0
33moyamoya disease10.0
34sudden infant death syndrome10.0
35pulmonary edema10.0
36dementia10.0
37dystonia10.0
38focal dystonia10.0
39intracranial hypertension10.0
40lactic acidosis10.0
41laryngitis10.0
42migraine10.0
43wallerian degeneration10.0
44myoclonus10.0
45syncope10.0
46endotheliitis10.0
47retinoblastoma10.0FOS, CASP3, CASP9, CREB1
48toxic encephalopathy10.0APP, FOS, CASP3, CREB1
49amyotrophic lateral sclerosis type 1410.0CASP3, APP, NOS1, IGF1
50b-cell lymphomas10.0CASP9, ITGB1, CASP3

Graphical network of the top 20 diseases related to Cerebral Hypoxia:



Diseases related to cerebral hypoxia

Symptoms for Cerebral Hypoxia

About this section

Drugs & Therapeutics for Cerebral Hypoxia

About this section

Drug clinical trials:

Search ClinicalTrials for Cerebral Hypoxia

Search NIH Clinical Center for Cerebral Hypoxia

Genetic Tests for Cerebral Hypoxia

About this section

Anatomical Context for Cerebral Hypoxia

About this section

MalaCards organs/tissues related to Cerebral Hypoxia:

32
Brain, Spleen, Cortex, Lung, Monocytes, Endothelial

Animal Models for Cerebral Hypoxia or affiliated genes

About this section

MGI Mouse Phenotypes related to Cerebral Hypoxia:

36 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.3NOS1, ITGB1, APP
2MP:00053718.2FOS, BMP7, ITGB1, IGF1
3MP:00053917.9NOS1, CASP3, PLAT, BMP7, ITGB1, FOS
4MP:00053777.8CASP3, IGF1, PLAT, BMP7, ITGB1, FOS
5MP:00107717.6CAMK4, APP, IGF1, ITGB1, BMP7, FOS
6MP:00053817.6CASP3, ITGB1, ITGAV, BMP7, NOS1, PLAT
7MP:00053807.6FOS, ITGB1, ITGAV, BMP7, CASP9, CREB1
8MP:00053677.5ITGAV, IGF1, BMP7, CASP3, NOS1, ITGB1
9MP:00053887.5CREB1, CASP9, CASP3, PLAT, BMP7, ITGB1
10MP:00028737.4IGF1, APP, NOS1, FOS, ITGB1, BMP7
11MP:00053827.3BMP7, ITGAV, ITGB1, FOS, CASP3, CASP9
12MP:00053907.0CAMK4, NOS1, PLAT, BMP7, ITGB1, CREB1
13MP:00053696.9IGF1, APP, ITGB1, PLAT, CASP3, CREB1
14MP:00053866.8FOS, CREB1, NOS1, PLAT, ITGAV, ITGB1
15MP:00053796.7IGF1, NOS1, CREB1, CAMK4, CASP3, BMP7
16MP:00053896.7APP, ITGB1, PLAT, CASP3, CAMK4, FOS
17MP:00053856.6ITGAV, BMP7, NOS1, CREB1, CASP3, CASP9
18MP:00053976.6FOS, ITGB1, CAMK4, CASP3, CASP9, ITGAV
19MP:00053766.2ITGAV, PLAT, NOS1, ITGB1, FOS, APP
20MP:00053846.0IGF1, APP, FOS, ITGAV, PLAT, CASP3
21MP:00053875.9BMP7, IGF1, APP, NOS1, CAMK4, CASP9
22MP:00036315.6PLAT, IGF1, APP, FOS, ITGB1, ITGAV
23MP:00053785.6NOS1, CREB1, CAMK4, CASP9, IGF1, FOS
24MP:00107685.6APP, IGF1, PLAT, FOS, ITGB1, ITGAV

Publications for Cerebral Hypoxia

About this section

Articles related to Cerebral Hypoxia:

(show top 50)    (show all 232)
idTitleAuthorsYear
1
Therapeutic benefits of delayed lithium administration in the neonatal rat after cerebral hypoxia-ischemia. (25211332)
2014
2
Targeted drug delivery to treat pain and cerebral hypoxia. (23343976)
2013
3
Cognitive decline in moyamoya: influence of chronic cerebral hypoxia, history of stroke, or comorbid conditions? (22171927)
2012
4
Experimental evidence of the potential use of erythropoietin by intranasal administration as a neuroprotective agent in cerebral hypoxia. (21756166)
2011
5
Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia. (19782128)
2010
6
Inhibition of integrin alphavbeta3 prevents urokinase plasminogen activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia. (19168722)
2009
7
Alternate pathways preserve tumor necrosis factor-alpha production after nuclear factor-kappaB inhibition in neonatal cerebral hypoxia-ischemia. (19628795)
2009
8
Mild cerebral hypoxia-ischemia produces a sub-acute transient inflammatory response that is less selective and prolonged after a substantial insult. (19631731)
2009
9
Enhancement of autophagic flux after neonatal cerebral hypoxia-ischemia and its region-specific relationship to apoptotic mechanisms. (19815706)
2009
10
"Therapeutic time window" duration decreases with increasing severity of cerebral hypoxia-ischaemia under normothermia and delayed hypothermia in newborn piglets. (17475224)
2007
11
Plasminogen activators contribute to impairment of hypercapnic and hypotensive cerebrovasodilation after cerebral hypoxia/ischemia in the newborn pig. (16141421)
2005
12
The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. (15592434)
2005
13
A novel role for an established player: anemia drug erythropoietin for the treatment of cerebral hypoxia/ischemia. (15294194)
2004
14
Extracellular superoxide concentration increases following cerebral hypoxia but does not affect cerebral blood flow. (15245758)
2004
15
Delayed postischemic hypothermia improves long-term behavioral outcome after cerebral hypoxia-ischemia in neonatal rats. (11861942)
2002
16
Caspase-3 activation after neonatal rat cerebral hypoxia-ischemia. (11275647)
2001
17
Detection and treatment of cerebral hypoxia key to avoiding intraoperative brain injuries. (12578096)
2000
18
Subcellular distribution of calcium and ultrastructural changes after cerebral hypoxia-ischemia in immature rats. (11154758)
2000
19
Impairment of mitochondrial respiration after cerebral hypoxia-ischemia in immature rats: relationship to activation of caspase-3 and neuronal injury. (11154759)
2000
20
Prevention of both T2- and diffusion-weighted increases in image intensity during cerebral hypoxia-ischemia in infant rats pretreated with dexamethasone. (10204774)
1999
21
Magnetic resonance imaging during cerebral hypoxia-ischemia: T2 increases in 2-week-old but not 4-week-old rats. (10022586)
1999
22
Cerebral hypoxia after cardiopulmonary resuscitation. (10073537)
1999
23
Effect of propentofylline on free radical generation during cerebral hypoxia in the newborn piglet. (9578400)
1998
24
Apoptosis in a neonatal rat model of cerebral hypoxia-ischemia. (9836776)
1998
25
Lipid free radical generation and brain cell membrane alteration following nitric oxide synthase inhibition during cerebral hypoxia in the newborn piglet. (9326283)
1997
26
Nuclear condensation and fragmentation following cerebral hypoxia-ischemia occurs more frequently in immature than older rats. (9089690)
1997
27
Neonatal cerebral hypoxia-ischemia: the effect of adenosine receptor antagonists. (9364488)
1997
28
Influence of age on the cerebral lesions in an immature rat model of cerebral hypoxia-ischemia: a light microscopic study. (9205806)
1997
29
Specific inhibition of apoptosis after cerebral hypoxia-ischaemia by moderate post-insult hypothermia. (8554576)
1995
30
DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat. (7614012)
1995
31
Syncope: a videometric analysis of 56 episodes of transient cerebral hypoxia. (8053660)
1994
32
Delayed-onset focal dystonia after diffuse cerebral hypoxia--two case reports. (8179837)
1993
33
Brain metabolism and blood flow in acute cerebral hypoxia studied by NMR spectroscopy and hydrogen clearance. (1550710)
1992
34
Experimental biology of cerebral hypoxia-ischemia: relation to perinatal brain damage. (1971436)
1990
35
Protective effect of KB-2796, a new calcium antagonist, in cerebral hypoxia and ischemia. (2241412)
1990
36
Cerebral hypoxia-ischemia in immature rats: methodological considerations. (3342854)
1988
37
Visual defects in children after cerebral hypoxia. (6525237)
1984
38
Early computed tomographic abnormalities following profound cerebral hypoxia. (6477220)
1984
39
The role of dilantin in the prevention of pulmonary edema associated with cerebral hypoxia. (7083868)
1982
40
Gray matter enhancement: a computerized tomographic sign of cerebral hypoxia. (7191063)
1980
41
Hyperventilation-induced cerebral hypoxia. (6774644)
1980
42
The morphologic consequences of cerebral hypoxia. (517287)
1979
43
Immediate restoration of central nervous system autonomic cardiopulmonary control: survival of "lethal" cerebral hypoxia by treatment with prostaglandin Bx. (401242)
1978
44
Effect of gamma-oxybutyric acid on the subcellular reaction to cerebral hypoxia [proceedings]. (885430)
1977
45
Barbiturate protection in cerebral hypoxia. (329713)
1977
46
Histopathologic and ultrastructural study in infantile encephalopathy by obstetrical cerebral hypoxia. (987614)
1976
47
The CSF lactate-pyruvate ratio in cerebral hypoxia. (5638919)
1968
48
Cardiac factors in cerebral hypoxia. (14020142)
1963
49
Action of cerebral hypoxia on the pulmonary arterial pressure of the dog (14437309)
1960
50
Cerebral hypoxia: aetiology and treatment. (13293396)
1956

Variations for Cerebral Hypoxia

About this section

Expression for genes affiliated with Cerebral Hypoxia

About this section
Expression patterns in normal tissues for genes affiliated with Cerebral Hypoxia

Search GEO for disease gene expression data for Cerebral Hypoxia.

Pathways for genes affiliated with Cerebral Hypoxia

About this section

Pathways related to Cerebral Hypoxia according to GeneCards/GeneDecks:

(show top 50)    (show all 113)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Amyotrophic lateral sclerosis (ALS)37
9.5NOS1, CASP9, CASP3
2
Show member pathways
9.5CASP9, CASP3, APP
39.2NOS1, CAMK4, APP, CREB1
4
Show member pathways
Alzheimers Disease37
9.2NOS1, CASP9, CASP3, APP
59.1FOS, CASP3, CASP9, CAMK4
6
Show member pathways
Calcium Regulation in the Cardiac Cell37
9.1CREB1, FOS, CAMK4, NOS1
79.1CASP3, FOS, CASP9, CREB1
8
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
9.1CASP3, CASP9, CREB1, FOS
9
Show member pathways
9.1FOS, CASP3, CASP9, CREB1
109.1FOS, CREB1, CAMK4, CASP3
11
Show member pathways
DNA damage response37
8.9CREB1, IGF1, CASP3, CASP9
128.9IGF1, PLAT, BMP7
13
Show member pathways
8.9ITGB1, FOS, CASP9, CASP3
14
Show member pathways
FAS pathway and Stress induction of HSP regulation37
Apoptosis and survival FAS signaling cascades60
Caspase cascade in apoptosis37
8.9CASP9, CASP3, APP, IGF1
15
Show member pathways
Prolactin Signaling Pathway37
Development Prolactin receptor signaling60
Leptin signaling pathway37
8.9ITGB1, FOS, CREB1, CASP3
16
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
8.8IGF1, FOS, CASP9, CASP3
17
Show member pathways
8.8IGF1, FOS, CASP3, CAMK4
18
Show member pathways
8.8CAMK4, CASP9, PLAT, CREB1, CASP3
19
Show member pathways
8.7CASP3, CREB1, CASP9, FOS, APP
20
Show member pathways
8.7BMP7, ITGAV, ITGB1
21
Show member pathways
8.7FOS, BMP7, CAMK4, NOS1, CREB1
22
Show member pathways
Immune response BCR pathway60
Fc-epsilon receptor I signaling in mast cells37
8.6ITGAV, FOS, CASP9, CREB1
23
Show member pathways
Cytoskeleton remodeling FAK signaling60
Development Endothelin 1 EDNRA transactivation of EGFR60
8.6ITGB1, IGF1, FOS, CREB1
248.6IGF1, CREB1, CASP9, CASP3, APP
25
Show member pathways
8.5CASP9, ITGB1, ITGAV, CASP3
26
Show member pathways
8.4ITGAV, CASP9, FOS, ITGB1
27
Show member pathways
8.4NOS1, CREB1, CAMK4, CASP3, FOS, APP
28
Show member pathways
8.4ITGAV, BMP7, CASP3, ITGB1
29
Show member pathways
8.4FOS, CASP9, CASP3, IGF1, BMP7
30
Show member pathways
Transcription Receptor mediated HIF regulation60
Development CNTF receptor signaling60
Class IB PI3K non-lipid kinase events37
ErbB2/ErbB3 signaling events37
Development Growth hormone signaling via PI3K AKT and MAPK cascades60
Translation Regulation activity of EIF260
Regulation of lipid metabolism Insulin signaling generic cascades60
Transcription PPAR Pathway60
Cell adhesion PLAU signaling60
Translation Regulation activity of EIF4F60
8.4ITGB1, PLAT, FOS, IGF1
31
Show member pathways
Development EGFR signaling via PIP360
Development PDGF signaling via MAPK cascades60
Apoptosis and survival Anti apoptotic action of membrane bound ESR160
Signaling of Hepatocyte Growth Factor Receptor37
Development EGFR signaling via small GTPases60
Development Neurotrophin family signaling60
Apoptosis and survival NGF signaling pathway60
Apoptosis and survival Role of CDK5 in neuronal death and survival60
8.3FOS, CASP3, ITGB1, CREB1, CASP9, CAMK4
32
Show member pathways
Signal transduction PTEN pathway60
8.3FOS, CASP3, CASP9, ITGB1, IGF1
338.2IGF1, ITGB1, ITGAV, CASP3
34
Show member pathways
8.1CAMK4, FOS, BMP7, CASP3, NOS1, CASP9
35
Show member pathways
Development EDNRB signaling60
Development ACM2 and ACM4 activation of ERK60
Cell adhesion Integrin inside out signaling60
Development G Proteins mediated regulation MARK ERK signaling60
Signal transduction IP3 signaling60
Development Angiotensin signaling via PYK260
Development EPO induced MAPK pathway60
8.1ITGAV, CAMK4, ITGB1, FOS, CREB1
36
Show member pathways
Integrin-mediated cell adhesion37
Focal Adhesion37
8.1ITGB1, ITGAV, FOS, IGF1
37
Show member pathways
8.1IGF1, ITGAV, ITGB1, FOS
38
Show member pathways
8.0ITGAV, CREB1, CASP3, ITGB1, FOS
397.9IGF1, ITGB1, ITGAV, CREB1, CASP9
40
Show member pathways
7.8CAMK4, PLAT, CASP9, CASP3, CREB1, IGF1
41
Show member pathways
7.7ITGB1, ITGAV, CASP9, CAMK4, CREB1, IGF1
42
Show member pathways
7.5CREB1, CAMK4, BMP7, ITGAV, ITGB1, IGF1
437.4IGF1, FOS, ITGAV, CASP3, CASP9, ITGB1
44
Show member pathways
7.3BMP7, FOS, ITGB1, ITGAV, CREB1, IGF1
45
Show member pathways
7.3APP, ITGB1, ITGAV, NOS1, IGF1, PLAT
46
Show member pathways
7.1IGF1, CREB1, FOS, ITGB1, ITGAV, BMP7
47
Show member pathways
6.7CAMK4, CASP3, CREB1, NOS1, CASP9, BMP7
48
Show member pathways
6.7CREB1, CASP3, IGF1, CASP9, FOS, ITGB1
49
Show member pathways
6.7FOS, ITGB1, ITGAV, CASP3, CASP9, CREB1
50
Show member pathways
6.4CASP3, BMP7, CASP9, CREB1, ITGAV, IGF1

Compounds for genes affiliated with Cerebral Hypoxia

About this section

Compounds related to Cerebral Hypoxia according to GeneCards/GeneDecks:

(show top 50)    (show all 135)
idCompoundScoreTop Affiliating Genes
1sulindac sulfide449.8CASP9, APP, CASP3
2cd 437449.6FOS, CASP3, CASP9
315-deoxy-delta-12,14-prostaglandin j2449.5CASP9, FOS, CASP3, CREB1
4pdtc449.5FOS, CASP3, NOS1, CASP9
5ethidium bromide449.5CASP3, CASP9, PLAT
6s-nitroso-n-acetylpenicillamine449.4NOS1, CASP9, CASP3
76-hydroxydopamine449.4APP, CASP3, FOS, CREB1
8corticosterone44 61 2411.4NOS1, CREB1, FOS, APP
9egcg449.4CASP3, APP, CASP9, FOS
10carbachol44 28 1111.4CREB1, APP, FOS, NOS1
11thapsigargin44 6110.3CREB1, CASP9, CASP3, APP
12lactacystin449.3APP, NOS1, CASP9, CREB1, CASP3
135-hydroxytryptamine449.3CREB1, NOS1, APP, PLAT
14simvastatin44 50 61 28 24 1114.3CASP9, CASP3, APP, PLAT
15sp 60012544 6110.3CASP9, CASP3, ITGB1, FOS
163-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide449.2CASP3, CASP9, APP
17isoproterenol44 1110.2NOS1, CREB1, PLAT, APP
18retinoid449.2CREB1, CAMK4, CASP9, FOS
194-hydroxynonenal44 2410.2CASP9, APP, FOS, CREB1, CASP3
20chelerythrine449.2IGF1, FOS, CREB1
21curcumin449.1CASP9, APP, CREB1, CASP3, FOS
22butyrate449.1CREB1, CASP9, CASP3, FOS, APP
23pge2449.0BMP7, CASP9, CREB1, NOS1, FOS
24titanium449.0ITGAV, ITGB1, BMP7
25rapamycin448.9CREB1, CASP9, IGF1, CASP3, BMP7
26nmda44 289.9FOS, CASP9, CAMK4, CREB1, APP, NOS1
27ly294002448.8FOS, CREB1, CASP9, CASP3, IGF1
28h2o2448.8CASP9, CREB1, FOS, NOS1, CASP3, APP
29dopamine44 28 24 1111.7IGF1, NOS1, FOS, APP, CREB1
30glutamine448.7NOS1, CREB1, ITGB1, IGF1, APP
31gnrh448.6IGF1, CREB1, FOS, APP, PLAT
32glutamate448.6CREB1, NOS1, CASP9, FOS, APP, PLAT
33calcitriol44 61 24 1111.6BMP7, IGF1, FOS, ITGB1, CREB1
34cyclosporin a44 28 6110.5CASP9, PLAT, ITGB1, NOS1, APP, CASP3
35adenylate448.5NOS1, CREB1, PLAT, FOS, APP
36creatinine448.4APP, IGF1, NOS1, PLAT, BMP7
37pd 98,059448.4IGF1, FOS, CREB1, CASP9, CASP3, ITGB1
38wortmannin448.4ITGB1, CASP3, CASP9, IGF1, CREB1, FOS
39phosphatidylinositol448.3ITGB1, FOS, CREB1, IGF1, CASP9, CASP3
40cysteine448.2NOS1, CASP3, PLAT, APP, ITGB1, CREB1
41estrogen448.1IGF1, FOS, ITGB1, NOS1, BMP7, CREB1
42sb 20358044 619.1NOS1, CASP3, CASP9, ITGB1, FOS, IGF1
43genistein44 28 61 2 24 1113.1ITGB1, FOS, IGF1, CASP9, CASP3, CREB1
44actinomycin d448.0APP, CASP9, CASP3, PLAT, FOS, IGF1
45dexamethasone44 50 28 1110.6NOS1, BMP7, CASP9, CREB1, APP, IGF1
46tyrosine447.2BMP7, ITGAV, CAMK4, CREB1, ITGB1, FOS
47cycloheximide447.2CREB1, FOS, NOS1, IGF1, ITGB1, BMP7
48retinoic acid44 247.8NOS1, FOS, CASP9, CASP3, PLAT, BMP7
49vegf446.7CASP3, BMP7, ITGAV, FOS, ITGB1, APP
50serine446.5FOS, NOS1, CREB1, CAMK4, CASP9, IGF1

GO Terms for genes affiliated with Cerebral Hypoxia

About this section

Cellular components related to Cerebral Hypoxia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1synapseGO:0452029.3APP, PLAT, NOS1
2integrin complexGO:0083059.0ITGAV, ITGB1
3cell surfaceGO:0099868.3PLAT, ITGAV, ITGB1, APP
4cytosolGO:0058298.1APP, FOS, CASP3, CASP9, CAMK4, NOS1
5extracellular vesicular exosomeGO:0700628.0CAMK4, PLAT, ITGAV, ITGB1, APP

Biological processes related to Cerebral Hypoxia according to GeneCards/GeneDecks:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1glial cell apoptotic processGO:03434910.2CASP9, CASP3
2activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome cGO:00863510.1CASP3, CASP9
3platelet formationGO:03022010.1CASP9, CASP3
4positive regulation of osteoclast differentiationGO:0456729.9CREB1, FOS
5Type I pneumocyte differentiationGO:0605099.8CREB1, IGF1
6SMAD protein signal transductionGO:0603959.8BMP7, FOS
7fibroblast growth factor receptor signaling pathwayGO:0085439.8CASP9, CAMK4, CREB1
8neuron apoptotic processGO:0514029.8CASP3, APP
9epidermal growth factor receptor signaling pathwayGO:0071739.7CREB1, CAMK4, CASP9
10Fc-epsilon receptor signaling pathwayGO:0380959.6FOS, CASP9, CREB1
11dendrite developmentGO:0163589.6BMP7, APP
12neurotrophin TRK receptor signaling pathwayGO:0480119.6CASP3, CASP9, CAMK4, CREB1
13regulation of multicellular organism growthGO:0400149.5IGF1, APP
14phosphatidylinositol-mediated signalingGO:0480159.5CREB1, CASP9, IGF1
15negative regulation of neuron differentiationGO:0456659.5BMP7, ITGB1, APP
16branching morphogenesis of an epithelial tubeGO:0487549.4BMP7, IGF1
17positive regulation of apoptotic processGO:0430659.2ITGB1, BMP7, CASP3, CASP9
18innate immune responseGO:0450879.1APP, FOS, CASP9, CAMK4, CREB1
19extrinsic apoptotic signaling pathway in absence of ligandGO:0971929.0CASP3, ITGAV, IGF1
20positive regulation of transcription, DNA-templatedGO:0458938.7IGF1, FOS, BMP7, CAMK4, CREB1
21negative regulation of extrinsic apoptotic signaling pathwayGO:20012378.7ITGAV, IGF1
22axon guidanceGO:0074118.7CREB1, BMP7, ITGAV, ITGB1
23extracellular matrix organizationGO:0301988.4APP, ITGB1, ITGAV, BMP7, CASP3
24positive regulation of transcription from RNA polymerase II promoterGO:0459448.3IGF1, APP, FOS, BMP7, CREB1, NOS1
25blood coagulationGO:0075967.7NOS1, PLAT, ITGAV, ITGB1, APP, IGF1

Molecular functions related to Cerebral Hypoxia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1virus receptor activityGO:0016189.1ITGB1, ITGAV
2protein bindingGO:0055155.2IGF1, APP, FOS, ITGB1, ITGAV, BMP7

Products for genes affiliated with Cerebral Hypoxia

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Cerebral Hypoxia

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet