MCID: CRB036
MIFTS: 30

Cerebral Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cerebral Meningioma

MalaCards integrated aliases for Cerebral Meningioma:

Name: Cerebral Meningioma 12 51 14 69
Meningioma of Cerebrum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6112
NCIt 46 C4807
SNOMED-CT 64 189164002
UMLS 69 C0542564

Summaries for Cerebral Meningioma

MalaCards based summary : Cerebral Meningioma, also known as meningioma of cerebrum, is related to meningioma, familial and cerebritis, and has symptoms including seizures and headache. An important gene associated with Cerebral Meningioma is DRD1 (Dopamine Receptor D1), and among its related pathways/superpathways are PEDF Induced Signaling and TGF-Beta Pathway. Affiliated tissues include skin and thyroid, and related phenotypes are endocrine/exocrine gland and growth/size/body region

Related Diseases for Cerebral Meningioma

Diseases related to Cerebral Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 10.3
2 cerebritis 10.3
3 adenoma 9.8
4 thyroiditis 9.8
5 parathyroid adenoma 9.8
6 thyroid cancer, nonmedullary, 1 9.6
7 bulimia nervosa 2 9.6
8 keratopathy 9.6
9 leukemia 9.6
10 papillary carcinoma 9.6
11 actinomycosis 9.6
12 tremor 9.6

Graphical network of the top 20 diseases related to Cerebral Meningioma:



Diseases related to Cerebral Meningioma

Symptoms & Phenotypes for Cerebral Meningioma

UMLS symptoms related to Cerebral Meningioma:


seizures, headache

MGI Mouse Phenotypes related to Cerebral Meningioma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.26 EGF IL6R LIFR PRLR
2 growth/size/body region MP:0005378 9.02 DRD1 EGF IL6R LIFR PRLR

Drugs & Therapeutics for Cerebral Meningioma

Search Clinical Trials , NIH Clinical Center for Cerebral Meningioma

Genetic Tests for Cerebral Meningioma

Anatomical Context for Cerebral Meningioma

MalaCards organs/tissues related to Cerebral Meningioma:

38
Skin, Thyroid

Publications for Cerebral Meningioma

Articles related to Cerebral Meningioma:

(show all 22)
# Title Authors Year
1
Uncommon association of cerebral meningioma, parathyroid adenoma and papillary thyroid carcinoma in a patient harbouring a rare germline variant in the CDKN1B gene. ( 26762354 )
2016
2
Cognitive and emotional problems in patients after cerebral meningioma surgery. ( 24763925 )
2014
3
Cerebral meningioma presenting as dystonic head tremor. ( 24259285 )
2014
4
Unexpected finding of cerebral meningioma on (11)C-PiB PET. ( 23429388 )
2013
5
An incidental finding of cerebral meningioma on 99mTc-TRODAT-1 dopamine transporter SPECT/CT. ( 22889784 )
2012
6
Unexpected finding on I-123 FP-CIT SPECT leading to the diagnosis of cerebral meningioma. ( 21220989 )
2011
7
Neuroparalytic keratopathy as the first sign of a cerebral meningioma. ( 17894293 )
2007
8
An unusual association of cerebral meningioma, parathyroid adenoma and thyroid papillary carcinoma. ( 16724700 )
2006
9
Can the calcitonin used for a shoulder-hand syndrome have a role in the revelation of a cerebral meningioma? ( 15589451 )
2004
10
Radiotherapy after surgery for benign cerebral meningioma. ( 15066300 )
2004
11
Radiation-induced skin ulcer, cerebral meningioma, and skin cancer following radiation and radium treatment for actinomycosis. ( 11994636 )
2002
12
[Estrogen and progesterone receptors in cerebral meningioma and their clinical value]. ( 12378940 )
2002
13
"Anorexia saved my life": coincidental anorexia nervosa and cerebral meningioma. ( 11746295 )
2001
14
Post-operative computed tomography in two dogs with cerebral meningioma. ( 11052366 )
2000
15
Formation of autocrine loops in human cerebral meningioma tissue by leukemia inhibitor factor, interleukin-6, and oncostatin M: inhibition of meningioma cell growth in vitro by recombinant oncostatin M. ( 9488310 )
1998
16
Inhibition of proliferation of human cerebral meningioma cells by suramin: effects on cell growth, cell cycle phases, extracellular growth factors, and PDGF-BB autocrine growth loop. ( 7897522 )
1995
17
Results of craniotomy for the treatment of cerebral meningioma in 42 cats. ( 8191679 )
1994
18
Presence of dopamine D1 receptors and absence of dopamine D2 receptors in human cerebral meningioma tissue. ( 1385626 )
1992
19
Hormonal dependency of cerebral meningiomas. Part 2: In vitro effect of steroids, bromocriptine, and epidermal growth factor on growth of meningiomas. ( 2213165 )
1990
20
Hormonal dependency of cerebral meningiomas. Part 1: Female sex steroid receptors and their significance as specific markers for adjuvant medical therapy. ( 2213164 )
1990
21
Radiation-induced cerebral meningioma: a recognizable entity. ( 6593438 )
1984
22
Foot and leg symptoms referrable to bilateral cerebral meningioma--a case report. ( 14028016 )
1962

Variations for Cerebral Meningioma

Expression for Cerebral Meningioma

Search GEO for disease gene expression data for Cerebral Meningioma.

Pathways for Cerebral Meningioma

Pathways related to Cerebral Meningioma according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.13 EGF IL6R LIFR PRLR
2
Show member pathways
12.94 EGF IL6R LIFR PRLR
3
Show member pathways
12.57 EGF IL6R LIFR PRLR
4
Show member pathways
12.48 EGF IL6R PRLR
5 11.77 EGF IL6R
6
Show member pathways
11.7 EGF IL6R
7 11.63 LIFR PRLR
8
Show member pathways
11.49 EGF PRLR
9 11.43 EGF IL6R
10 11.43 EGF IL6R
11 11.31 DRD1 EGF
12
Show member pathways
11.3 EGF IL6R LIFR PRLR
13
Show member pathways
11.09 IL6R LIFR
14 10.96 EGF PRLR
15 10.64 EGF IL6R

GO Terms for Cerebral Meningioma

Cellular components related to Cerebral Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.46 EGF IL6R LIFR PRLR
2 plasma membrane GO:0005886 9.35 DRD1 EGF IL6R LIFR PRLR
3 receptor complex GO:0043235 8.62 EGF LIFR

Biological processes related to Cerebral Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.5 EGF IL6R LIFR
2 cytokine-mediated signaling pathway GO:0019221 9.4 IL6R LIFR
3 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.37 EGF IL6R
4 response to cytokine GO:0034097 9.26 IL6R LIFR
5 mammary gland alveolus development GO:0060749 9.16 EGF PRLR
6 activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 8.96 EGF PRLR
7 ciliary neurotrophic factor-mediated signaling pathway GO:0070120 8.62 IL6R LIFR

Molecular functions related to Cerebral Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor activity GO:0004896 8.96 IL6R LIFR
2 ciliary neurotrophic factor receptor activity GO:0004897 8.62 IL6R LIFR

Sources for Cerebral Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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