Aliases & Classifications for Cerebral Meningioma

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Sources:
8Disease Ontology, 44Novoseek, 61UMLS, 39NCIt, 56SNOMED-CT
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Aliases & Descriptions for Cerebral Meningioma:

Name: Cerebral Meningioma 8 44 61
 
Meningioma of Cerebrum 8


External Ids:

Disease Ontology8 DOID:6112
SNOMED-CT56 189164002
NCIt39 C4807

Summaries for Cerebral Meningioma

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MalaCards based summary: Cerebral Meningioma, also known as meningioma of cerebrum, is related to adenoma and leukemia. An important gene associated with Cerebral Meningioma is DRD1 (dopamine receptor D1), and among its related pathways are Ovarian Infertility Genes and Signaling events mediated by PTP1B. The compounds cmdb7 and bromocriptine have been mentioned in the context of this disorder. Affiliated tissues include skin and thyroid, and related mouse phenotypes are vision/eye and limbs/digits/tail.

Related Diseases for Cerebral Meningioma

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Diseases related to Cerebral Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 66)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma29.7PRLR, LIFR, OSM, IGF1
2leukemia29.3OSM, LIFR, PRLR, IL6, EGF
3cerebritis10.7
4ovarian disease10.4ESR1
5meningioma, familial10.3PGR, ESR1
6cribriform carcinoma10.3PGR, ESR1
7progesterone resistance10.3PGR, ESR1
8mammary paget's disease10.3PGR, ESR1
9malignant mixed mullerian tumor10.3PGR, ESR1
10bilateral breast cancer10.3ESR1, PGR
11leiomyomatosis10.3PGR, ESR1
12adenosarcoma10.3PGR, ESR1
13breast disease10.3PGR, ESR1
14myoma10.3ESR1, PGR
15endometrial stromal sarcoma10.2ESR1, PGR
16uterine fibroid10.2ESR1, PGR
17inflammatory breast carcinoma10.2ESR1, PGR
18lymphangioleiomyomatosis10.2ESR1, PGR
19angiomyolipoma10.2ESR1, PGR
20cervical adenocarcinoma10.2PGR, ESR1
21breast cancer10.2PGR, ESR1
22gynecomastia10.2ESR1, PGR
23ductal carcinoma in situ10.2ESR1, PGR
24tubular adenocarcinoma10.2PGR, ESR1
25breast ductal carcinoma10.2ESR1, PGR
26smooth muscle tumor10.2PGR, ESR1
27leprechaunism10.2IGF1, EGF
28breast fibroadenoma10.2PGR, ESR1
29endometrial cancer10.2ESR1, PGR
30hyperprolactinemia10.2PRLR, IGF1
31classic kaposi sarcoma10.2IL6
32li-fraumeni syndrome10.1PGR, ESR1, PRLR
33osteoporosis10.1IGF1, ESR1
34leiomyoma10.1EGF, ESR1, PGR
35infertility10.1ESR1, LIFR, PRLR
36acromegaly10.0PRLR, IGF1
37choriocarcinoma10.0OSM, LIFR, EGF
38pituitary adenoma10.0PRLR, LIFR, IGF1
39anorexia nervosa10.0
40keratopathy10.0
41actinomycosis10.0
42papillary carcinoma10.0
43parathyroid adenoma10.0
44thyroiditis10.0
45tremor10.0
46prolactinoma10.0LIFR, ESR1, IGF1
47periodontitis9.9IL6, OSM
48ovarian cancer, somatic9.9PGR, ESR1, EGF
49glioblastoma9.9EGF, PRLR, OSM
50alzheimer disease9.9OSM, IL6, DRD1

Graphical network of the top 20 diseases related to Cerebral Meningioma:



Diseases related to cerebral meningioma

Symptoms for Cerebral Meningioma

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Drugs & Therapeutics for Cerebral Meningioma

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Drug clinical trials:

Search ClinicalTrials for Cerebral Meningioma

Search NIH Clinical Center for Cerebral Meningioma

Genetic Tests for Cerebral Meningioma

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Anatomical Context for Cerebral Meningioma

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MalaCards organs/tissues related to Cerebral Meningioma:

31
Skin, Thyroid

Animal Models for Cerebral Meningioma or affiliated genes

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Publications for Cerebral Meningioma

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Articles related to Cerebral Meningioma:

(show all 21)
idTitleAuthorsYear
1
Cerebral meningioma presenting as dystonic head tremor. (24259285)
2014
2
Cognitive and emotional problems in patients after cerebral meningioma surgery. (24763925)
2014
3
Unexpected finding of cerebral meningioma on (11)C-PiB PET. (23429388)
2013
4
An incidental finding of cerebral meningioma on 99mTc-TRODAT-1 dopamine transporter SPECT/CT. (22889784)
2012
5
Unexpected finding on I-123 FP-CIT SPECT leading to the diagnosis of cerebral meningioma. (21220989)
2011
6
Neuroparalytic keratopathy as the first sign of a cerebral meningioma. (17894293)
2007
7
An unusual association of cerebral meningioma, parathyroid adenoma and thyroid papillary carcinoma. (16724700)
2006
8
Radiotherapy after surgery for benign cerebral meningioma. (15066300)
2004
9
Can the calcitonin used for a shoulder-hand syndrome have a role in the revelation of a cerebral meningioma? (15589451)
2004
10
Estrogen and progesterone receptors in cerebral meningioma and their clinical value]. (12378940)
2002
11
Radiation-induced skin ulcer, cerebral meningioma, and skin cancer following radiation and radium treatment for actinomycosis. (11994636)
2002
12
"Anorexia saved my life": coincidental anorexia nervosa and cerebral meningioma. (11746295)
2001
13
Post-operative computed tomography in two dogs with cerebral meningioma. (11052366)
2000
14
Formation of autocrine loops in human cerebral meningioma tissue by leukemia inhibitor factor, interleukin-6, and oncostatin M: inhibition of meningioma cell growth in vitro by recombinant oncostatin M. (9488310)
1998
15
Inhibition of proliferation of human cerebral meningioma cells by suramin: effects on cell growth, cell cycle phases, extracellular growth factors, and PDGF-BB autocrine growth loop. (7897522)
1995
16
Results of craniotomy for the treatment of cerebral meningioma in 42 cats. (8191679)
1994
17
Presence of dopamine D1 receptors and absence of dopamine D2 receptors in human cerebral meningioma tissue. (1385626)
1992
18
Hormonal dependency of cerebral meningiomas. Part 2: In vitro effect of steroids, bromocriptine, and epidermal growth factor on growth of meningiomas. (2213165)
1990
19
Hormonal dependency of cerebral meningiomas. Part 1: Female sex steroid receptors and their significance as specific markers for adjuvant medical therapy. (2213164)
1990
20
Radiation-induced cerebral meningioma: a recognizable entity. (6593438)
1984
21
Foot and leg symptoms referrable to bilateral cerebral meningioma--a case report. (14028016)
1962

Variations for Cerebral Meningioma

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Expression for genes affiliated with Cerebral Meningioma

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Search GEO for disease gene expression data for Cerebral Meningioma.

Pathways for genes affiliated with Cerebral Meningioma

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Pathways related to Cerebral Meningioma according to GeneCards Suite gene sharing:

(show all 37)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8PRLR, PGR
29.7EGF, PRLR
39.5IGF1, EGF
49.5LIFR, OSM
59.3IGF1, IL6
6
Show member pathways
Development Ligand dependent activation of the ESR1 AP 1 pathway59
9.3ESR1, PRLR
7
Show member pathways
Nuclear Receptors36
9.3ESR1, PGR
8
Show member pathways
Cell cycle ESR1 regulation of G1 S transition59
Immune response MIF JAB1 signaling59
Cell cycle Cell cycle generic schema 59
9.3PGR, ESR1
99.2ESR1, EGF
10
Show member pathways
9.2PRLR, IGF1, EGF
11
Show member pathways
Transcription Receptor mediated HIF regulation59
Development CNTF receptor signaling59
Class IB PI3K non-lipid kinase events36
ErbB2/ErbB3 signaling events36
Development Growth hormone signaling via PI3K AKT and MAPK cascades59
Translation Regulation activity of EIF259
Regulation of lipid metabolism Insulin signaling generic cascades59
Transcription PPAR Pathway59
Cell adhesion PLAU signaling59
Translation Regulation activity of EIF4F59
9.1LIFR, IGF1, EGF
12
Show member pathways
8.9PGR, PRLR, ESR1
13
Show member pathways
8.9EGF, IGF1, IL6
14
Show member pathways
Translation Non genomic rapid action of Androgen Receptor59
8.9IGF1, EGF, IL6
15
Show member pathways
8.9EGF, IGF1, IL6
16
Show member pathways
PLK2 and PLK4 events36
Polo-like kinase signaling events in the cell cycle36
8.9IGF1, EGF, IL6
17
Show member pathways
8.9IL6, IGF1, EGF
188.9IL6, EGF, IGF1
198.9IL6, EGF, IGF1
20
Show member pathways
8.9IGF1, LIFR, IL6
218.7EGF, ESR1, IGF1
22
Show member pathways
Type III interferon signaling36
8.5PRLR, LIFR, OSM, IL6
23
Show member pathways
8.5PGR, ESR1, PRLR, EGF
24
Show member pathways
8.5EGF, IGF1, LIFR, IL6
25
Show member pathways
8.5EGF, IL6, LIFR, IGF1
26
Show member pathways
8.5IL6, EGF, LIFR, IGF1
27
Show member pathways
Development Ligand independent activation of ESR1 and ESR259
8.4DRD1, IGF1, ESR1, EGF
28
Show member pathways
8.1LIFR, IGF1, EGF, PRLR, IL6
29
Show member pathways
8.1OSM, LIFR, PRLR, IL6, EGF
308.1IL6, PRLR, OSM, EGF, IGF1
318.0PRLR, IGF1, OSM, LIFR, IL6
32
Show member pathways
7.9IL6, EGF, LIFR, IGF1, OSM
33
Show member pathways
7.9EGF, IL6, LIFR, IGF1, OSM
34
Show member pathways
7.7IGF1, PGR, ESR1, PRLR, DRD1, EGF
35
Show member pathways
7.6EGF, ESR1, IGF1, LIFR, IL6
36
Show member pathways
7.6EGF, IL6, LIFR, ESR1, IGF1
37
Show member pathways
7.1IGF1, EGF, ESR1, LIFR, OSM, IL6

Compounds for genes affiliated with Cerebral Meningioma

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Compounds related to Cerebral Meningioma according to GeneCards Suite gene sharing:

(show top 50)    (show all 116)
idCompoundScoreTop Affiliating Genes
1cmdb7449.7IGF1, EGF
2bromocriptine44 28 1111.6PRLR, DRD1, IGF1
3ici 164384449.6ESR1, PGR
4idoxifene449.6PGR, ESR1
5triphenylethylene449.5PGR, ESR1
6fluoxymesterone44 1110.5ESR1, PRLR
7norgestimate44 1110.3PGR, ESR1
8dichlorodiphenyltrichloroethane449.3OSM, ESR1
9progestins449.3PRLR, PGR, ESR1
10lapatinib44 50 1111.3PGR, ESR1, EGF
11fulvestrant44 50 28 1112.2PGR, ESR1, EGF
12nandrolone44 2410.2IGF1, PGR, ESR1
13droloxifene449.2IGF1, ESR1, PGR
14leuprolide acetate449.2ESR1, PGR, IGF1
15trastuzumab44 50 1111.2ESR1, PGR, EGF
16clomiphene citrate449.2PGR, IGF1, ESR1
17letrozole44 50 60 1112.1ESR1, PGR, IGF1
18estrone sulfate44 2410.1IGF1, ESR1, PGR
19raloxifene44 50 28 1112.1IGF1, PGR, ESR1
20indomethacin44 28 60 1111.9OSM, EGF, PGR, IL6
21geldanamycin44 50 60 1111.9EGF, ESR1, PGR
224-hydroxytamoxifen448.8EGF, IGF1, PGR, ESR1
23mifepristone44 28 60 1111.8ESR1, PGR, EGF
24estrone44 28 24 1111.8PGR, ESR1, IGF1
25dihydrotestosterone44 28 24 1111.7EGF, ESR1, PGR, IGF1
26acth448.7OSM, IGF1, LIFR, IL6
27paclitaxel44 50 1110.7PGR, EGF, LIFR, ESR1
28phosphatidylinositol448.7IGF1, PRLR, DRD1, EGF, OSM
29pd 98,059448.7OSM, EGF, IL6, IGF1
30cysteine448.6DRD1, EGF, PRLR, PGR, OSM
31megestrol acetate448.6IGF1, IL6, ESR1, PGR
32gp 130448.6OSM, IL6, LIFR
33alanine448.4LIFR, IL6, OSM, PGR, PRLR
34progestin448.4PGR, IGF1, EGF, PRLR, ESR1
35thymidine44 249.4IL6, PRLR, OSM, EGF, IGF1
36tamoxifen44 50 28 1111.4PRLR, ESR1, PGR, IGF1, EGF
37ly294002448.3IGF1, ESR1, IL6, EGF
38actinomycin d448.3EGF, IGF1, ESR1, IL6
39gnrh448.1IGF1, DRD1, EGF, PRLR, ESR1, PGR
40dexamethasone44 50 28 1111.1EGF, IL6, PRLR, PGR, OSM, IGF1
41progesterone44 28 60 24 1112.0LIFR, PRLR, ESR1, PGR, IGF1, EGF
42testosterone44 60 24 1110.8IL6, PRLR, PGR, IGF1, ESR1, EGF
43tyrosine447.7EGF, DRD1, IL6, PRLR, LIFR, OSM
44vegf447.6ESR1, PGR, IL6, OSM, IGF1, EGF
45estradiol44 24 119.6OSM, PGR, ESR1, PRLR, DRD1, IGF1
46retinoic acid44 248.6PGR, IGF1, IL6, ESR1, EGF, OSM
47steroid447.5IGF1, OSM, PGR, ESR1, LIFR, PRLR
48cycloheximide447.3EGF, OSM, IGF1, PGR, ESR1, PRLR
49genistein44 28 60 1 24 1112.0EGF, IL6, PRLR, ESR1, PGR, OSM
50estrogen446.5IGF1, OSM, PGR, ESR1, LIFR, PRLR

GO Terms for genes affiliated with Cerebral Meningioma

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Cellular components related to Cerebral Meningioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.5EGF, IGF1
2extracellular spaceGO:00056158.1IGF1, OSM, IL6, EGF
3extracellular regionGO:00055768.0EGF, IL6, PRLR, LIFR, IGF1

Biological processes related to Cerebral Meningioma according to GeneCards Suite gene sharing:

(show all 27)
idNameGO IDScoreTop Affiliating Genes
1activation of transmembrane receptor protein tyrosine kinase activityGO:000717110.1PRLR, EGF
2positive regulation of cerebellar granule cell precursor proliferationGO:00219409.9IGF1, EGF
3positive regulation of DNA bindingGO:00433889.9EGF, IGF1
4branching morphogenesis of an epithelial tubeGO:00487549.8EGF, IGF1
5positive regulation of mitosisGO:00458409.8EGF, IGF1
6positive regulation of acute inflammatory responseGO:00026759.7OSM, IL6
7negative regulation of hormone secretionGO:00468889.7IL6, OSM
8positive regulation of protein import into nucleus, translocationGO:00331609.7IGF1, IL6
9mammary gland alveolus developmentGO:00607499.6ESR1, EGF
10positive regulation of DNA replicationGO:00457409.6IGF1, IL6
11response to heatGO:00094089.5OSM, IL6
12positive regulation of smooth muscle cell proliferationGO:00486619.5IGF1, IL6
13prostate epithelial cord arborization involved in prostate glandular acinus morphogenesisGO:00605279.5IGF1, ESR1
14positive regulation of peptidyl-serine phosphorylationGO:00331389.4OSM, IL6
15positive regulation of osteoblast differentiationGO:00456699.3IGF1, IL6
16positive regulation of nitric oxide biosynthetic processGO:00454299.3IL6, ESR1
17positive regulation of fibroblast proliferationGO:00481469.3IGF1, ESR1
18negative regulation of gene expressionGO:00106299.3ESR1, PGR
19positive regulation of epithelial cell proliferationGO:00506799.2IGF1, IL6
20platelet activationGO:00301689.2IGF1, IL6, EGF
21positive regulation of MAPK cascadeGO:00434109.2OSM, IL6, IGF1
22positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.2IGF1, IL6, OSM
23positive regulation of protein kinase B signalingGO:00518979.0IGF1, IL6
24negative regulation of cell proliferationGO:00082858.9IL6, IGF1, OSM
25signal transductionGO:00071658.6EGF, ESR1, PGR, IGF1
26positive regulation of cell proliferationGO:00082848.3EGF, IGF1, OSM, LIFR, IL6
27positive regulation of transcription from RNA polymerase II promoterGO:00459448.3OSM, ESR1, IL6, IGF1

Molecular functions related to Cerebral Meningioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1steroid hormone receptor activityGO:00037079.3ESR1, PGR
2steroid bindingGO:00054969.2ESR1, PGR
3growth factor activityGO:00080838.4EGF, IL6, OSM, IGF1
4protein bindingGO:00055156.8IGF1, PGR, ESR1, PRLR, IL6, DRD1

Sources for Cerebral Meningioma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet