Summaries for Cerebritis

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44Wikipedia, 22MalaCards
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Wikipedia: Cerebritis is an infection of the brain that normally leads to the formation of an abscess within the...44 more...

MalaCards: Cerebritis is related to neuronitis and carcinoma. An important gene associated with Cerebritis is APP (amyloid beta (A4) precursor protein), and among its related pathways are Cellular Apoptosis Pathway and Antioxidant Action of Vitamin-C. The compounds copper and threonine have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, whole blood and brain, and related mouse phenotypes are skeleton and vision/eye.

Aliases & Descriptions for Cerebritis

Sources:
6Disease Ontology, 43UMLS, 27NCIt
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Aliases & Descriptions:

cerebritis 6 43

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Related Diseases for Cerebritis

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13GeneCards, 14GeneDecks
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Diseases related to cerebritis by text searches and GeneDecks gene sharing:

(show top 50)    (show all 1152)
idRelated DiseaseScoreTop Affiliating Genes
1neuronitis221.3PIK3R1, PICK1, PIK3C2A, PIK3CG, LRP1, LRP2
2carcinoma209.2PIGF, PIK3R1, PIK3R5, PIK3C2A, PIK3CG, LRP1
3prostatitis167.1PIK3R1, PIK3R5, PIK3C2A, PIK3CG, LRP1, LRP2
4leukemia159.8PIK3R1, PIK3R5, PIK3C2A, PIK3CG, LRP1, LRP6
5alzheimer's disease159.4PIK3R1, PIK3CG, LRP1, LRP2, LRP6, LRP8
6ischemia152.6PIGF, PIK3C2A, PIK3CG, COG2, KLF4, NDFIP1
7adenocarcinoma143.3PIK3R1, PIK3C2A, PIK3CG, LRP1, KLF4, KLF6
8thyroiditis137.0PIGF, PIK3R1, PIK3C2A, PIK3CG, LRP1, LRP2
9hypoxia135.9PIGF, PIK3R1, PIK3C2A, PIK3CG, LRP1, PDE4A
10hypertension133.4PIK3R1, PIK3C2A, PIK3CG, LRP1, LRP6, LRP8
11retinitis132.0PIGF, PIK3C2A, PIK3CG, LRP1, LRP2, KLF6
12arthritis131.6PIK3CG, LRP1, LRP2, NDEL1, NCF1, PDE4A
13melanoma130.7PIK3R1, PIK3R5, PIK3C2A, PIK3CG, LRP1, KLF6
14cholesterol130.6PIK3R1, PIK3C2A, PIK3CG, LRP1, LRP2, LRP6
15atherosclerosis127.9PIK3C2A, PIK3CG, LRP1, LRP2, LRP6, LRP8
16rheumatoid arthritis122.5PIK3CG, LRP1, LRP2, NDEL1, PDE4A, RELA
17malaria118.1LRP1, KLF4, PDE4A, REN, CNTF, KITLG
18schizophrenia116.6PIK3R1, PICK1, PIK3CG, LRP2, NDE1, NDEL1
19diabetes mellitus114.8PIK3R1, PIK3R5, PIK3C2A, PIK3CG, LRP6, COG2
20myocardial infarction112.1PIK3C2A, PIK3CG, LRP1, LRP8, COG2, PDE4A
21multiple sclerosis112.1LRP1, NCAM1, PDE4A, RELA, RELN, CNP
22obesity108.2PIK3R1, PIK3C2A, PIK3CG, LRP1, COG2, RELA
23cervicitis102.7PIK3CG, PDE4A, RELA, REN, CNR1, KITLG
24pancreatitis100.8PIK3R1, PIK3R5, PIK3C2A, PIK3CG, LRP1, LRP2
25lupus erythematosus100.1PIGF, PIK3C2A, PIK3CG, LRP2, COG2, CNTF
26dementia98.2PIK3C2A, PIK3CG, LRP1, LRP8, NCAM1, PDE4A
27astrocytoma96.7PIK3R1, PIK3CG, LRP1, KLF6, NCAM1, RELA
28pneumonia94.4PIK3C2A, COG2, PDE4A, RELA, VTN, GCH1
29nephropathy93.9LRP1, LRP2, COG2, REG1A, RELA, REN
30anemia85.6NDFIP1, NCAM1, RELA, REN, SGCB, SGK1
31gonococcal synovitis84.9PIK3R1, PIK3CG, LRP1, KLF4, NCAM1, PDE4A
32thrombosis84.8PIK3C2A, PIK3CG, LRP1, COG2, REN, VWF
33neurodegeneration83.2PIK3CG, LRP1, LRP2, RELN, SGK1, CNR1
34colorectal cancer82.7PIK3R1, PIK3R5, PIK3CG, LRP2, LRP6, COG2
35cerebral infarction82.3COG2, NCF1, VWF, RBP4, SELP, SERPINE2
36neuropathy82.2PIK3C2A, NCAM1, PDE4A, REN, CNR1, CNTF
37cadasil81.2COG2, REN, CNR1, CNTF, VWF, GC
38insulin resistance80.8PIK3R1, PIK3CG, LRP1, COG2, RELA, REN
39seizures80.8PIK3C2A, PDCD10, CNP, CNR1, CNTF, CNTNAP2
40blindness80.2PIK3C2A, PIK3CG, COG2, PDE4A, REN, CNR1
41neuroblastoma79.2PIK3R1, PIK3CG, LRP1, KLF4, KLF6, NCAM1
42hepatocellular carcinoma77.1PIK3R1, PIK3CG, KLF6, NCAM1, REG1A, RELA
43lateral sclerosis75.8CNR1, CNTF, CNTN4, SELE, SERPINE2, SETD2
44fibrosis75.5PIK3CG, LRP1, KLF6, NCF1, PDE4A, REG1A
45homocysteine75.3PIK3R1, PIK3C2A, COG2, NCF1, RELA, REN
46type 2 diabetes mellitus74.9PIK3R1, PIK3C2A, LRP6, COG2, REN, CNR1
47brain injury74.9NDFIP1, NCAM1, CNR1, VWF, SELP, SERPINC1
48amyotrophic lateral sclerosis74.6CNR1, CNTF, CNTN4, SELE, SERPINE2, SETD2
49ovarian cancer74.4PIK3R1, PIK3CG, LRP1, KLF6, NCAM1, NCF1
50lymphoblastic leukemia74.4PIK3CG, COG2, NCAM1, RELA, CNTNAP2, KITLG

Graphical network of the top 20 diseases related to cerebritis:



Graphical network of diseases related to cerebritis

Clinical Features for Cerebritis

Drugs & Therapeutics for Cerebritis

Sources:
4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials
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Approved drugs:

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Genetic Tests for Cerebritis

Anatomical Context for Cerebritis

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22MalaCards
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MalaCards organs/tissues related to cerebritis:

22
Bone marrow, Whole blood, Brain, Cortex, Cerebellum, Retina, Spinal cord, Heart, Smooth muscle, Skeletal muscle, Small intestine, Colon, Kidney, Liver, Lung, Thyroid, Skin, Prostate, Monocytes, Nk cells, T cells, B lymphoblasts, B cells, Endothelial, Fetal brain, Prefrontal cortex, Cingulate cortex, Parietal lobe, Temporal lobe, Ciliary ganglion, Olfactory bulb, Thalamus, Hypothalamus, Caudate nucleus, Amygdala, Pons, Trigeminal ganglion, Cardiac myocytes, Fetal liver, Fetal lung, Fetal thyroid, Adrenal cortex, Pituitary

Phenotypes for genes affiliated with Cerebritis

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25MGI
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MGI Mouse Phenotypes related to cerebritis:

25 (show all 30)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1skeleton phenotypeMP:0005390INFPIK3CG, LRP1, LRP2, LRP6, RELA, CNP
2vision/eye phenotypeMP:0005391INFLRP2, LRP6, NCAM1, PDCD10, RELA, RELN
3normal phenotypeMP:0002873INFPIK3R1, LRP1, LRP6, LRP8, KLF4, NCK2
4nervous system phenotypeMP:0003631INFPICK1, LRP1, LRP6, LRP8, NDE1, NDEL1
5no phenotypic analysisMP:0003012INFPIK3R1, LRP2, LRP6, NCS1, REST, SGK1
6growth/size phenotypeMP:0005378INFPIK3R1, PIK3C2A, PIK3CG, LRP1, LRP2, LRP6
7embryogenesis phenotypeMP:0005380INFLRP6, KLF6, NDEL1, NCK2, PDCD10, REST
8other phenotypeMP:0005395INFCNR1, VASP, RARB, KDR, LEPR, LDLR
9tumorigenesisMP:0002006INFPIK3R1, KLF4, PDCD10, KITLG, SERPINE1, VHL
10cellular phenotypeMP:0005384INFPIK3R1, PICK1, PIK3R5, PIK3CG, LRP2, LRP6
11liver/biliary system phenotypeMP:0005370INFLRP6, KLF6, NDFIP1, GCK, SERPINC1, SENP1
12immune system phenotypeMP:0005387INFPIK3R5, LRP1, NDFIP1, PDCD10, PDE4A, REN
13muscle phenotypeMP:0005369INFPIK3R1, PIK3CG, LRP1, PDCD10, RELA, RELN
14craniofacial phenotypeMP:0005382INFLRP2, LRP6, KLF4, PDCD10, KITLG, NAGLU
15pigmentation phenotypeMP:0001186INFKITLG, BTD, SERPINC1, VLDLR, NAGLU, LMNA
16taste/olfaction phenotypeMP:000539414.2PDE4A, CNR1, CNTNAP2, PAX6, BDNF, BBS2
17hematopoietic system phenotypeMP:0005397INFKLF6, NDFIP1, PDCD10, CNTF, PCNA, SERPIND1
18hearing/vestibular/ear phenotypeMP:0005377INFLRP2, LRP6, KITLG, NAGLU, LMNA, LMO4
19renal/urinary system phenotypeMP:0005367INFLRP2, LRP6, NCK2, REN, SGK1, GCK
20adipose tissue phenotypeMP:0005375INFPIK3R1, PIK3C2A, LRP1, LRP6, CNR1, SERPINE1
21endocrine/exocrine gland phenotypeMP:0005379INFPICK1, LRP2, KLF4, NDFIP1, REG1A, CNP
22mortality/agingMP:0010768INFPIK3C2A, LRP1, LRP6, LRP8, KLF4, KLF6
23digestive/alimentary phenotypeMP:0005381INFLRP2, LRP6, KLF4, RELN, CNP, KITLG
24cardiovascular system phenotypeMP:0005385INFPIK3R1, PIK3CG, LRP1, KLF6, PDCD10, PDE4A
25integument phenotypeMP:0010771INFPIK3CG, LRP6, KLF4, KLF6, NDFIP1, PDCD10
26limbs/digits/tail phenotypeMP:0005371INFLRP6, NDFIP1, RELA, KITLG, PCNT, VHL
27reproductive system phenotypeMP:0005389INFPICK1, LRP6, LRP8, KLF4, KLF6, REG1A
28behavior/neurological phenotypeMP:0005386INFLRP1, LRP2, LRP6, LRP8, KLF4, NCAM1
29homeostasis/metabolism phenotypeMP:0005376INFPIK3R1, PIK3C2A, PIK3CG, LRP1, LRP2, LRP6
30respiratory system phenotypeMP:0005388INFLRP2, LRP6, NDFIP1, CNP, SELP, LPL

Publications for genes affiliated with Cerebritis

Sources:
35PubMed
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Articles related to cerebritis:

(show top 50)    (show all 2691)
idTitleAuthorsYearAffiliating Genes
1The clinical significance of S100I^ protein in cerebr ospinal fluid and serum from the patients with cerebral hemorrhage]. (21906477)Sheng L.... Ci C.H.2011S100B
2Cerebral autosomal dominant arteriopathy with subcort ical infarcts and leukoencephalopathy: a genetic cause of cerebral small vessel disease. (20386637)Choi J.C.2010NOTCH3
3SNP improves cerebral hemodynamics during normotensio n but fails to prevent sex dependent impaired cerebral autoregulation during hy potension after brain injury. (20298682)Armstead W.M.... Vavilala M.S.2010ADM
4Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria. (20003529)Conroy A.L.... Kain K.C.2009ANGPT1, ANGPT2
5Small heat shock proteins associated with cerebral amyloid angiopathy of hereditary cerebral hemorrhage with amyloidosis (Dutch type) induce interleukin-6 secretion. (17629591)Wilhelmus M.M.... Verbeek M.M.2009IL6, HSPB8, HSPB6
6Cerebral amyloid angiopathy: a common cause of cerebr al hemorrhage. (19601795)Pezzini A.... Padovani A.2009APP, GSN, TTR
7Beneficial effect of dipyridyl, a liposoluble iron chelator against focal cerebral ischemia: in vivo and in vitro evidence of protection of cerebral endothelial cells. (18177633)MActhy D.... Marie C.2008HMOX1
8Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms. (18635848)Aoki T.... Hashimoto N.2008CTSB, ELN, CST3
9Early onset West syndrome with cerebral hypomyelination and reduced cerebral white matter. (18065176)Tohyama J.... Ohno K.2008PHGDH
10The contribution of cerebral vascular semicarbazide-sensitive amine oxidase to cerebral amyloid angiopathy in Alzheimer's disease. (17971074)Jiang Z.J.... Yu P.H.2008AOC3
11Reduced cerebral blood flow but elevated cerebral glucose metabolic rate in erythropoietin overexpressing transgenic mice with excessive erythrocytosis. (16804549)Frietsch T.... Waschke K.F.2007EPO
12Cerebral vascular accumulation of Dutch-type Abeta42, but not wild-type Abeta42, in hereditary cerebral hemorrhage with amyloidosis, Dutch type. (17628026)Nishitsuji K.... Mori H.2007APP
13Delivery of anti-platelet-endothelial cell adhesion molecule single-chain variable fragment-urokinase fusion protein to the cerebral vasculature lyses arterial clots and attenuates postischemic brain edema. (17389242)Danielyan K.... Muzykantov V.R.2007PLAU
14Effects of the selective endothelin A (ET(A)) recepto r antagonist Clazosentan on cerebral perfusion and cerebral oxygenation followi ng severe subarachnoid hemorrhage - preliminary results from a randomized clini cal series. (17700991)Barth M.... Vajkoczy P.2007EDNRA
15Correspondence between the time course of cerebral vasospasm and the level of cerebral dopamine-beta-hydroxylase in rabbits. (16777494)Kovacic S.... Ravnik J.2006DBH
16Inhibitory mechanisms of tetramethylpyrazine in middle cerebral artery occlusion (MCAO)-induced focal cerebral ischemia in rats. (16557454)Hsiao G.... Sheu J.R.2006NOS2
17Gene expression profiling in the human middle cerebral artery after cerebral ischemia. (17116215)Vikman P.... Edvinsson L.2006SMTN
18Methylation status of RARbeta gene promoter in low and high grade cerebral glioma. Comparison with normal tissue. Immuno-histochemical study of nuclear RARbeta expression in low and high grade cerebral glioma cells. Comparison with normal cells. 48 tumors (16389900)Klein O.... Marchal J.C.2005RARB, NR1H2
19Cerebral venous malformations have distinct genetic origin from cerebral cavernous malformations. (16239636)Guclu B.... Gunel M.2005KRIT1, CCM2, PDCD10
20Cerebral small vessel diseases: cerebral microangiopa thies. (15791150)Ringelstein E.B.... Nabavi D.G.2005NOTCH3
21Candidate genes of cerebral infarction and traditional classification in Koreans with cerebral infarction. (16019571)Um J.Y.... Hong S.H.2005ACE, APOE, AGT
22Association between apolipoprotein E e4 allele and arteriosclerosis, cerebral amyloid angiopathy, and cerebral white matter damage in Alzheimer's disease. (15090562)Tian J.... Mann D.M.2004APOE
23Human C-reactive protein increases cerebral infarct size after middle cerebral artery occlusion in adult rats. (15545914)Gill R.... Pepys M.B.2004CRP
24Regional cerebral oxygen saturation is a sensitive marker of cerebral hypoperfusion during orthotopic liver transplantation. (15271702)Plachky J.... Weigand M.A.2004ENO2
25KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortex. (15046662)Guzeloglu-Kayisli O.... Gunel M.2004KRIT1, ITGB1BP1
26Simultaneous monitoring of somatosensory evoked potentials and regional cerebral oxygen saturation combined with serial measurement of plasma levels of cerebral specific proteins for the early diagnosis of postoperative brain damage in cardiovascular surgery. (15083339)Oki A.... Takaba T.2004CKB
27Neurotoxicity and physicochemical properties of Abeta mutant peptides from cerebral amyloid angiopathy: implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease. (12944403)Murakami K.... Shirasawa T.2003APP
28Angiopoietin-1 reduces cerebral blood vessel leakage and ischemic lesion volume after focal cerebral embolic ischemia in mice. (12150788)Zhang Z.G.... Chopp M.2002TEK, ANGPT1
29Overexpression of semicarbazide sensitive amine oxidase in the cerebral blood vessels in patients with Alzheimer's disease and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. (11872247)Ferrer I.... Unzeta M.2002AOC3
30Gene therapy for cerebral infarction (cerebral ischemia) (11968812)Ishida A.... Morishita R.2002GDNF
31The role of cerebral oedema in the pathogenesis of cerebral malaria. (11523587)Sanni L.A.2001IDO1
32A specific thrombin inhibitor (argatroban) ameliorate d cerebral blood flow in the patients with acute cerebral infarction. (10750365)Maruki Y.... Shimazu K.2000SERPINC1
33Expression of transforming growth factor-beta1, 2, 3 isoforms and type I and II receptors in acute focal cerebral ischemia: an immunohistochemical study in rat after transient and permanent occlusion of middle cerebral artery. (10334481)Ata K.A.... TerAcnt A.1999TGFBR1
34Lack of difference in iron status assessed by soluble transferrin receptor between children with cerebral malaria and those with non-cerebral malaria. (10401196)Kivibidila S.... Tshefu K.A.1999TFRC
35Case-control study of risk of cerebral sinus thrombosis in oral contraceptive users and in [correction of who are] carriers of hereditary prothrombotic conditions. The Cerebral Venous Sinus Thrombosis Study Group. (9518910)de Bruijn S.F.... Vandenbroucke J.P.1998SERPINC1, F5
36Progressive decrease of cerebral cytochrome C oxidase activity in sparse-fur mice: role of acetyl-L-carnitine in restoring the ammonia-induced cerebral energy depletion. (9086462)Rao K.V.... Qureshi I.A.1997OTC, CPOX
37Opposite effects of L-arginine and nitroglycerin on cerebral blood velocity: nitric oxide precursors and cerebral blood velocity. (9260860)Micieli G.... Nappi G.1997AHSP
38Cerebral and umbilical vascular resistance response to vibroacoustic stimulation in growth-restricted fetuses. (9397109)Loy G.L.... Chiang L.M.1997FGR
39Intravenous infusion of adrenomedullin and increase in regional cerebral blood flow and prevention of ischemic brain injury after middle cerebral artery occlusion in rats. (8978383)Dogan A.... Yoshida J.1997ADM
40Role of endothelin-1 in cerebral hematoma-induced mod ification of cerebral vascular reactivity in piglets. (8896820)Yakubu M.A.... Leffler C.W.1996EDN1
41Cerebral microvessels in Alzheimer's have reduced protein kinase C activity. (8544906)Grammas P.... Roher A.1995DYT10
42Application of alteplase in prevention of cerebral vasospasm and its sequelae in patients after aneurysmal subarachnoid hemorrhage from ruptured cerebral aneurysm (7566413)Majchrzak H.... LadziA8ski P.1995PLAT
43Middle cerebral artery occlusion with unilateral moy amoya like vessels and with ruptured anterior cerebral artery aneurysm--its rel ation to the antiphospholipid antibody syndrome (7826715)Inoue R.... Hori S.1994APOH
44Ubiquitinated neurites are associated with preamyloid and cerebral amyloid beta deposits in patients with hereditary cerebral hemorr hage with amyloidosis Dutch type. (8384771)Tagliavini F.... Frangione B.1993RPS27A
45Nitric oxide synthase-containing neural processes on large cerebral arteries and cerebral microvessels. (7681722)Iadecola C.... Zhang F.1993BLVRB
46Acute-phase proteins in stroke: influences of its cause (cerebral hemorrhage or infarction), of the cerebral site of infarction, and of the sex of patients. (1716456)Ionescu D.A.... Scu M.G.1991APP
47The role of cerebral microvessel endothelium in regulation of cerebral blood flow through production of endothelin-1. (1725350)Yoshimoto S.... Murota S.1991EDN1
48Cerebral protection during reperfusion with superoxide dismutase in focal cerebral ischemia. (2396569)Pereira B.M.... Fishman R.A.1990SOD1
49TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. (1978068)Kwiatkowski D.... Greenwood B.M.1990TNF, IFNG
50Diagnosis of cerebral amyloid angiopathy with cerebral hemorrhage by enzyme linked immunosorbent assay (ELISA) of cystatin C in the cerebrospinal fluid (2364630)Shimode K.... Tsunematsu T.1990CST3

Expression for genes affiliated with Cerebritis

Sources:
1BioGPS
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Expression patterns in normal tissues for genes affiliated with Cerebritis

Pathways for genes affiliated with Cerebritis

Sources:
36QIAGEN, 20KEGG, 41Thomson Reuters, 10EMD Millipore
See all sources

Pathways related to cerebritis according to GeneDecks:

(show top 50)    (show all 196)
idPathwayScoreTop Affiliating Genes
1Cellular Apoptosis Pathway36INFPIK3R1, KITLG, BMP6, BMP7, UTS2, BID
2Antioxidant Action of Vitamin-C36INFNCF1, KITLG, MYH1, BMP6, BMP7, RAC1
3Renin-Angiotensin Pathway36INFPIK3R1, REN, KITLG, VCAM1, BMP6, BMP7
4Signaling Involved in Cardiac Hypertrophy36INFPIK3R1, RAF1, RAC1, LIF, LIFR, ATF6
5CDC42 Pathway36INFRAF1, LIMK1, LIFR, KDR, MUSK, BAIAP2
6Rho Family GTPases36INFPIK3R1, KITLG, VIM, BMP6, BMP7, RAF1
7Nanog in Mammalian ESC Pluripotency36INFKITLG, BMP6, BMP7, RAF1, UTS2, LIFR
8Akt Signaling36INFPIK3R1, PIK3CG, BMP7, RAF1, UTS2, LIF
9Mitochondrial Apoptosis36INFPIK3R1, KITLG, BMP6, BMP7, UTS2, BID
10Alzheimers Disease Pathway36INFLRP1, LIFR, BACE2, CDK5, CDK5R1, INSR
11JAK-STAT Pathway36INFPIK3R1, KITLG, MYC, BMP6, BMP7, RAF1
12Telomerase Components in Cell Signaling36INFKITLG, MYC, BMP6, BMP7, UTS2, BDNF
13mTOR Pathway3619.3PIK3R1, KITLG, BMP6, BMP7, RAC1, UTS2
14Regulation of eIF4 and p70S6K3617.7PIK3R1, BAX, CD4, ITGA1, ITGA2, ITGB1
15Chagas disease (American trypanosomiasis)2016.9PIK3R1, PIK3R5, PIK3CG, RELA, SERPINE1, MYD88
16Dopamine-DARPP32 Feedback onto cAMP Pathway3616.7KCNA5, KCNH3, KCNH5, KCNS3, KCNA2, KCND3
17SOCS Pathway3616.4BMP6, BMP7, BCL2, BAX, JAK2, CD4
18Malaria2016.4LRP1, SELE, SELP, VCAM1, MYD88, SDC2
19PGC1Alpha Pathway3616.0BMP6, BMP7, BCL2, BAX, CD4, INSR
20Reelin Pathway (Cajal-Retzius cells)3616.0LRP6, LRP8, NDEL1, RELN, CNR1, VLDLR
21Ceramide Pathway3615.4PIK3R1, RAF1, BAD, ATF6, JUN, FOS
22Actin-Based Motility by Rho Family GTPases3614.5BMP7, UTS2, LIMK1, PAK3, BDNF, BAIAP2
23BAD Phosphorylation3614.4RAF1, BCL2, BCL2L1, YWHAE, BAD, IRS1
24Development_VEGF signaling via VEGFR2 - generic cascades4114.3PIK3R1, RELA, VEGFA, VCL, RAF1, RAC1
25Toll-like receptor signaling pathway2014.2PIK3R1, PIK3R5, PIK3CG, RELA, MYD88, RAC1
26Jak-STAT signaling pathway2014.1PIK3R1, PIK3R5, PIK3CG, CNTF, MYC, LIFR
27Amyotrophic lateral sclerosis (ALS)2013.8RAC1, BID, BCL2, BCL2L1, BAD, BAX
28Apoptosis and survival FAS signaling cascades1013.6LMNA, LMNB1, LMNB2, BID, PARP1, BCL2
29PKR Pathway3613.6RELA, CHUK, JUN, FOS, MAPK8, MAP2K4
30Apoptosis and survival_TNFR1 signaling pathway4113.4RELA, BID, BCL2, CHUK, BAX, XIAP
31Apoptosis and survival TNFR1 signaling pathway1013.3RELA, BID, CHUK, BAX, XIAP, CFLAR
32EGF Pathway3612.6PIK3R1, NCK2, MYC, RAF1, RAC1, CHUK
33Signal transduction AKT signaling1011.3PIK3R1, IRS1, HSP90AB1, TRAP1, PPP2CB, PPP2CA
34Toxoplasmosis20INFPIK3R1, PIK3R5, PIK3CG, RELA, MYD88, BCL2
35Phospholipase-C Pathway36INFKITLG, BMP6, BMP7, RAF1, RAC1, UTS2
36Alzheimers disease20INFLRP1, LPL, BID, SDHB, BACE1, BACE2
37Colorectal Cancer Metastasis36INFPIK3R1, LRP6, MYC, BCL2L1, BAX, AXIN2
38Tec Kinases Signaling36INFPIK3R1, KITLG, MYD88, BMP6, BMP7, RAC1
39RAR-Gamma-RXR-Alpha Degradation36INFBMP7, LIF, UBE3A, UBC, IL12A, IL15
40NF-KappaB (p50-p65) Pathway36INFPIK3R1, RELA, KITLG, MYD88, BMP6, BMP7
41TGF-Beta Pathway36INFPIK3R1, KITLG, BMP6, BMP7, UTS2, BDNF
42ERK5 Signaling36INFKITLG, MYC, BMP6, BMP7, UTS2, BDNF
43Chemokine Signaling36INFPIK3R1, JUN, JAK2, FOS, GRB2, IL8
44IP3 Pathway36INFPIK3R1, KITLG, BMP6, BMP7, UTS2, BDNF
45STAT3 Pathway36INFMYC, BMP6, BMP7, RAF1, RAC1, LIF
46DHA Signaling36INFPIK3R1, KITLG, BMP6, BMP7, UTS2, BID
47all-trans-Retinoic Acid Signaling in Brain36INFBMP6, BMP7, RARB, LIF, BCL2, BAX
48CREB Pathway36INFPIK3R1, KITLG, BMP6, BMP7, UTS2, BDNF
49Focal adhesion20INFPIK3R1, PIK3R5, PIK3CG, RELN, VWF, VTN
50MAPK Family Pathway36INFPIK3R1, KITLG, BMP6, BMP7, RAF1, RAC1

Compounds for genes affiliated with Cerebritis

Sources:
32Novoseek , 18HMDB, 9DrugBank, 42Tocris Bioscience, 34PharmGKB
See all sources

Compounds related to cerebritis according to GeneDecks:

(show top 50)    (show all 529)
idCompoundScoreTop Affiliating Genes
1copper32 18 INFRBP4, SERPINA1, NAGLU, LPA, LIF, BLZF1
2threonine32 INFLPAR3, VASP, RAF1, LIMK1, PARK2, PAK3
3valine32 INFRBP4, SERPINA3, VIM, VIP, LPL, RAF1
4pertussis32 INFPIK3CG, VIP, LPAR1, CHRM2, P2RY2, JUN
5cholesterol32 9 18 9 INFPIK3R1, PIK3C2A, LRP1, LRP2, LRP8, COG2
6ganglioside32 INFNCAM1, CNTF, VIM, CD59, CD4, CD40
7polysaccharide32 INFNCAM1, KITLG, VTN, SELE, SELP, SERPINE2
8forskolin32 42 9 9 35.0PIK3R1, PDE4A, REN, SGCB, CNP, CNTF
9gtp32 22.1PIK3R1, PIK3C2A, SGCB, GCK, GCH1, VIP
10hydrocortisone32 9 9 22.4REN, KITLG, VIM, BMP6, LIF, BGLAP
11pge132 18.2PIK3C2A, PDE4A, VWF, SERPINE1, VIP, VASP
12tetrodotoxin32 17.5CNR1, SERPINE2, VIP, UTS2, BDNF, SCT
13corticosterone32 18 18.3CNR1, VIP, LIF, BGLAP, BDNF, LEPR
1415-deoxy-delta-12,14-prostaglandin j232 16.5PIK3CG, SERPINE1, VEGFA, VCAM1, MYC, BMP6
15pravastatin32 34 9 18 9 20.3PIK3C2A, COG2, SELE, SELP, SERPINE1, LPA
16ccl432 16.0S100B, MMP13, MET, IL12B, IL13, IL15
17gold32 15.6PIK3C2A, KITLG, RBP4, SERPINA3, NAGLU, VCL
18phenobarbital32 9 9 17.2PCNA, LPL, MYC, CHRNA7, CHRNA4, GUSB
19ang ii32 15.2PIK3CG, REN, VEGFA, JAK2, CD36, IL6ST
20iloprost32 42 9 9 17.9PDE4A, SELE, SELP, SERPINC1, VCAM1, GUSB
21protamine32 14.8SELP, SERPINC1, SERPINE1, LPL, INS, FGA
22lithium32 34 9 18 9 18.8PIK3R1, REN, NAGLU, BDNF, CDK5, ITPR1
23methylcellulose32 14.7KITLG, VCL, LIF, CD59, CD34, FGF2
24fluoxetine32 34 9 9 17.0CNR1, BDNF, SCT, IL10, MAOA, MAOB
25citrulline32 18 14.8SGCB, PC, VIM, VIP, BLVRB, ASL
26fe2+32 13.7SGCB, BLVRB, BLZF1, PAH, MT-CYB, INTS2
27ivig32 13.6PIK3C2A, VWF, SEPSECS, IL18R1, IL1RAPL2, IL3
28aminoguanidine32 9 9 15.5LEP, JAK2, IL1B, APOB, AOC3, IFNG
29go 697632 42 14.4PIK3CG, MMP2, IL8, MAPK8, MAPK3, MAPK14
30amiloride32 9 9 15.0REN, VIP, BCHE, SCNN1A, ITIH4, ASIC1
31cyclophosphamide32 34 9 9 15.0ITGB2, APOH, MBL2, F8, LTF, TAC1
32mannose32 INFLRP1, GCK, VCL, LMAN1, CEACAM3, CD79A
33trastuzumab32 34 9 9 INFPIK3R1, PIK3CG, RAF1, KDR, CDKN1B, CDKN3
34bromodeoxyuridine32 INFPIK3R1, NCAM1, CNP, CNTF, CNTN2, KITLG
35staurosporin32 INFPIK3CG, BCL2, BCL2L1, JUN, CDKN3, IL8
36phosphatidylserine32 9 9 INFVWF, SELE, VIM, LPL, LMNB1, RAC1
37gf 109203x32 42 INFPIK3CG, KITLG, VEGFA, VCL, RAF1, JUN
38formaldehyde32 18 INFVWF, PCNA, SELE, SELP, VIM, BLVRB
39paclitaxel32 34 9 9 INFPIK3CG, KITLG, PCNA, SETD2, VIM, VEGFA
40imatinib32 34 9 9 INFPIK3R1, PIK3CG, KITLG, VIP, VEGFA, MYC
41glucose32 INFPDE4A, CNTF, PC, GCH1, BTD, SETD2
42atp32 INFPIK3C2A, NCAM1, PDE4A, SGCB, VTN, PC
43adriamycin32 INFVIM, MYC, MYCN, BCL2, BCL2L1, BAX
44n-ethylmaleimide32 9 9 INFVWF, VTN, MYC, BLZF1, CDKN3, INSR
45thyroxine32 18 INFPIK3C2A, LRP2, COG2, REN, VWF, PCNA
46simvastatin32 34 42 9 18 9 INFPIK3C2A, COG2, KITLG, VWF, RBP4, SELE
47thalidomide32 42 9 9 INFPDE4A, VTN, VEGFA, KDR, BCL2L1, CHUK
48resveratrol32 9 18 9 INFPIK3CG, PCNA, VEGFA, RAF1, BID, PARP1
49txb232 INFREN, VWF, SELP, SERPINF2, NAGLU, LPA
50raloxifene32 9 9 INFVWF, SERPINC1, SERPINE1, BGLAP, CKB, CHKB

GO Terms for genes affiliated with Cerebritis

Sources:
12Gene Ontology
See all sources

Cellular components related to cerebritis according to GeneDecks:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1neuronal cell bodyGO:043025INFCNTF, CNTN2, CNTNAP2, SERPINE2, PAFAH1B1, SDC2
2extracellular regionGO:005576INFLRP8, NDFIP1, NCAM1, REG1A, CNTN4, KITLG
3cytosolGO:005829INFPIK3R1, PIK3R5, PIK3C2A, PIK3CG, NDE1, NDEL1
4mitochondrionGO:005739INFPICK1, SGK1, PC, BZRAP1, GCK, GCDH
5membraneGO:016020INFPIK3R5, PIK3CG, LRRC4C, PDE4A, REN, CNTNAP2
6perinuclear region of cytoplasmGO:048471INFPICK1, NDFIP1, NCS1, PDE4A, CNP, GC
7membrane raftGO:045121INFSELE, CLN3, P2RX1, JAK2, CD79A, CD36
8cell surfaceGO:009986INFLRP6, NCAM1, CNTN2, CNTNAP2, VLDLR, VEGFA
9external side of plasma membraneGO:00989719.1NCAM1, VWF, SELP, VCAM1, KDR, KCNJ5
10axonGO:03042415.8NCS1, CNTF, CNTN4, CNTNAP2, GC, VIM
11platelet alpha granule lumenGO:03109315.8VWF, SERPINF2, SERPINA1, SERPINE1, VEGFA, MMRN1
12postsynaptic membraneGO:04521114.4NCS1, CHRM2, CHRNA7, CHRNA3, CHRM1, CHRNB2
13postsynaptic densityGO:01406914.0PICK1, NCS1, CHRNA3, CHRM1, CDK5, CDK5R1
14protein phosphatase type 2A complexGO:00015913.5CYCS, PPP2R5B, PPP2R5D, PPP2R1A, PPP2R5E, PPP2R5C
15cytoplasmGO:005737INFPICK1, PIK3R5, PIK3C2A, PIK3CG, LRP1, KLF6
16integral to plasma membraneGO:005887INFLRP1, SGCB, CNR1, CNTN2, PCDH11X, SELP
17dendriteGO:030425INFRELN, CNTNAP2, KCND3, CHRM2, CHRNA3, CHRNA4
18extracellular spaceGO:005615INFLRP2, RELN, REN, CNP, CNTF, KITLG
19caveolaGO:005901INFLRP6, LRP8, SELE, CLN3, SDPR, KCNA5
20plasma membraneGO:005886INFPIK3R1, PICK1, PIK3C2A, PIK3CG, LRP2, LRP6
21neuron projectionGO:043005INFRASGRF1, LIMK1, CLN3, , CDH13, ITGA1
22cell junctionGO:030054INFPICK1, NCS1, CHRM2, CHRNA7, CHRNA3, CHRM1

Biological processes related to cerebritis according to GeneDecks:

(show top 50)    (show all 59)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of apoptotic processGO:043065INFLRP6, REST, CNR1, SEPT4, LPAR1, RARB
2blood coagulationGO:007596INFPIK3R1, PIK3R5, PIK3CG, LRP8, VWF, SELP
3neuron migrationGO:001764INFRELN, CNTN2, KIAA0319, PCNT, PAFAH1B1, PAX6
4positive regulation of cell proliferationGO:008284INFPDCD10, REG1A, CNTF, VIP, VIPR1, VEGFA
5cell deathGO:008219INF, CLN5, CLN6, CLN3, CLN8, PARK7
6platelet activationGO:030168INFPIK3R1, PIK3R5, PIK3CG, VWF, SELP, SERPINF2
7cell adhesionGO:007155INFNCAM1, RELN, CNTN2, CNTN5, CNTNAP2, KITLG
8nervous system developmentGO:007399INFNDEL1, CNTN4, SEMA5B, VLDLR, NAGLU, VEGFA
9axon guidanceGO:007411INFNCAM1, NCK2, RELN, CNTN2, CNTN4, VASP
10cell-cell signalingGO:007267INFCGA, AVP, ITGB2, INS, FGF13, FGF14
11brain developmentGO:007420INFRELN, CNTN4, CNTNAP2, SEPT4, BID, ZIC1
12response to drugGO:04249324.2LRP2, PDE4A, REN, VLDLR, LPL, MYC
13synaptic transmissionGO:00726823.5PICK1, CNP, VIPR1, LPAR3, RASGRF1, RAF1
14inflammatory responseGO:00695422.7PIK3CG, RELA, SELE, SELP, SERPINA3, MYD88
15immune responseGO:00695520.3VTN, VIPR1, BMP6, RAET1E, LIF, CHUK
16anti-apoptosisGO:00691618.6RELA, SERPINB2, VHL, MYD88, PAFAH2, BDNF
17G-protein coupled receptor signaling pathwayGO:00718618.0PIK3R5, PIK3CG, VIP, VIPR1, LPAR1, RAMP2
18positive regulation of angiogenesisGO:04576616.5SERPINE1, VEGFA, RAMP2, UTS2, KDR, CHRNA7
19cytokine-mediated signaling pathwayGO:01922115.8LRP8, KLF6, NCAM1, RELA, VCAM1, MYD88
20leukocyte migrationGO:05090015.7PIK3R1, SELP, FYN, JAM3, CD34, CD47
21response to ethanolGO:04547115.4CNR1, RBP4, BGLAP, BCL2, CHAT, CHRNB2
22negative regulation of neuron apoptotic processGO:04352415.4CNTF, CLN3, PARK7, PARK2, BDNF, BCL2
23elevation of cytosolic calcium ion concentrationGO:00720415.4GCK, LPAR1, LPAR3, UTS2, BDKRB2, S1PR3
24positive regulation of cell migrationGO:03033515.3VEGFA, KDR, CGA, JAK2, CDH13, ITGAV
25nerve growth factor receptor signaling pathwayGO:04801115.2PIK3R1, RELA, MYD88, RASGRF1, RAF1, RAC1
26response to organic cyclic compoundGO:01407014.5BTG2, SELP, SERPINA1, MSH2, JUN, CDKN1A
27cell-matrix adhesionGO:00716014.4CNTN2, VTN, VCL, RAC1, BCL2L11, JAM3
28positive regulation of peptidyl-tyrosine phosphorylationGO:05073114.3LRP8, RELN, KITLG, VTN, VEGFA, LIF
29response to woundingGO:00961114.3VWF, RAC1, PAX6, MET, GRIN2A, MDK
30memoryGO:00761314.1CNR1, VLDLR, CHRNA7, CHAT, CHRNB2, MUSK
31positive regulation of smooth muscle cell proliferationGO:04866113.9SERPINF2, MYD88, JUN, CDH13, FLT1, IL13
32cerebral cortex developmentGO:02198713.9NDE1, CNTNAP2, VLDLR, PAFAH1B1, BBS2, BBS4
33positive regulation of phosphatidylinositol 3-kinase cascadeGO:01406813.7RELN, CNTF, SELP, KDR, UBE3A, JAK2
34activation of MAPK activityGO:00018712.9LPAR1, LPAR3, PAK3, CHRNA7, UBC, S1PR2
35positive regulation of nitric oxide biosynthetic processGO:04542912.4JAK2, INS, INSR, IL1B, IFNG, ICAM1
36positive regulation of MAP kinase activityGO:04340611.8PIK3R5, PIK3CG, PDCD10, KITLG, VEGFA, CD40
37positive regulation of transcription from RNA polymerase II promoterGO:045944INFLRP6, KLF4, KLF6, NCK2, RELA, SERPINF2
38negative regulation of cell proliferationGO:008285INFKLF4, NCK2, REST, BTG2, SERPINE2, VHL
39positive regulation of MAPK cascadeGO:043410INFCNTF, LPAR1, LPAR3, LIF, KDR, LEP
40negative regulation of apoptotic processGO:043066INFPIK3CG, PDCD10, RELA, BTG2, SERPINE1, VEGFA
41transmembrane transportGO:055085INFGCK, AVP, AVPR2, ATP6V0D1, ATP1A2, ATP2A3
42angiogenesisGO:001525INFPIK3CG, PDCD10, SETD2, SERPINE1, VEGFA, RAMP2
43agingGO:007568INFLRP2, CNR1, VCAM1, P2RY2, JUN, ASS1
44platelet degranulationGO:002576INFVWF, SELP, SERPINF2, SERPINA1, SERPINE1, VEGFA
45apoptotic processGO:006915INFPDCD10, SGK1, PCNT, SEPT4, VIM, LMNA
46response to lipopolysaccharideGO:032496INFCNR1, GCH1, SELE, SELP, SERPINA1, S100A8
47signal transductionGO:007165INFLRP8, NDFIP1, NCK2, PDE4A, CNTF, CNTNAP2
48response to hypoxiaGO:001666INFSERPINA1, VEGFA, VCAM1, MYOCD, RAF1, UTS2
49small molecule metabolic processGO:044281INFPIK3R1, PIK3R5, PIK3C2A, PIK3CG, LRP2, PC
50regulation of blood pressureGO:008217INFREN, SGK1, GCH1, RAMP2, UTS2, LEP

Molecular functions related to cerebritis according to GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:005515INFPIK3R1, PICK1, PIK3CG, LRP1, LRP2, LRP6
2protein homodimerization activityGO:042803INFLRP6, PDCD10, VWF, GCH1, SERPINF2, NAGA
3growth factor activityGO:00808318.3REG1A, CNTF, KITLG, VEGFA, BMP6, BMP7
4identical protein bindingGO:04280217.7PICK1, RELA, CNTN2, PCNA, VIM, LMAN1
5cytokine activityGO:00512517.7CNTF, KITLG, VEGFA, BMP6, BMP7, LIF
6drug bindingGO:00814413.9CNR1, CHKA, CHRM2, CHRM1, MT2A, MT3
7receptor bindingGO:005102INFPICK1, LRP6, REN, CNTNAP2, SERPINE2, SERPINE1
8heparin bindingGO:008201INFVTN, SELP, SERPINE2, SERPINC1, SERPIND1, VEGFA
9ATP bindingGO:005524INFPIK3C2A, PIK3CG, SGK1, PC, GCK, MYH1
10enzyme bindingGO:019899INFPICK1, CNTNAP2, VHL, RAC1, BLZF1, BCHE

Sources for Cerebritis

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS