MCID: CRB009
MIFTS: 39

Cerebritis malady

Categories: Neuronal diseases

Aliases & Classifications for Cerebritis

Aliases & Descriptions for Cerebritis:

Name: Cerebritis 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3431
NCIt 47 C27199
UMLS 69 C0742115

Summaries for Cerebritis

MalaCards based summary : Cerebritis is related to cerebral palsy and cerebral amyloid angiopathy. An important gene associated with Cerebritis is SETD2 (SET Domain Containing 2), and among its related pathways/superpathways are Chromatin Regulation / Acetylation and PKMTs methylate histone lysines. The drugs Fibrinolytic Agents and Plasminogen have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and endothelial, and related phenotype is adipose tissue.

Wikipedia : 71 Cerebritis is an infection of the brain that normally leads to the formation of an abscess within the... more...

Related Diseases for Cerebritis

Diseases related to Cerebritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1637)
id Related Disease Score Top Affiliating Genes
1 cerebral palsy 12.3
2 cerebral amyloid angiopathy 12.3
3 cerebral palsy, ataxic, autosomal recessive 12.1
4 transient cerebral ischemia 12.1
5 cerebral cavernous malformations 3 12.1
6 cerebral cavernous malformations-1 12.1
7 cerebral amyloid angiopathy, dutch, italian, iowa, flemish, arctic variants 12.1
8 cerebral atherosclerosis 12.1
9 spastic cerebral palsy 12.1
10 cerebral aneurysms 12.0
11 cerebral hypoxia 12.0
12 cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 12.0
13 dyskinetic cerebral palsy 12.0
14 cerebral folate deficiency 12.0
15 spastic diplegia cerebral palsy 12.0
16 cerebral cavernous malformations-2 12.0
17 cerebral atrophy 12.0
18 cerebral ventricle cancer 12.0
19 vasculopathy, retinal, with cerebral leukodystrophy 12.0
20 hereditary cerebral amyloid angiopathy 12.0
21 cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome 12.0
22 reversible cerebral vasoconstriction syndrome 11.9
23 cerebral palsy, spastic quadriplegic, 1 11.9
24 cerebral arteriosclerosis 11.9
25 microcephaly, progressive, seizures, and cerebral and cerebellar atrophy 11.9
26 mixed cerebral palsy 11.9
27 cerebral palsy athetoid 11.9
28 cerebral creatine deficiency syndrome 3 11.9
29 deafness, dystonia, and cerebral hypomyelination 11.9
30 cerebral arteritis 11.9
31 cerebral palsy, spastic quadriplegic, 2 11.9
32 cerebral creatine deficiency syndrome 1 11.8
33 neurodegeneration due to cerebral folate transport deficiency 11.8
34 middle cerebral artery infarction 11.8
35 childhood-onset cerebral x-linked adrenoleukodystrophy 11.8
36 cerebral creatine deficiency syndrome 2 11.8
37 cerebral artery occlusion 11.8
38 cerebral cavernous malformation, familial 11.8
39 cerebral lymphoma 11.8
40 posterior cerebral artery infarction 11.8
41 malaria 11.8
42 spastic diplegia 11.8
43 cerebral meningioma 11.8
44 anterior cerebral artery infarction 11.8
45 spastic quadriplegia 11.8
46 cerebral arterial disease 11.8
47 cerebral primitive neuroectodermal tumor 11.8
48 spastic hemiplegia 11.8
49 cerebral hemorrhage 11.7
50 cerebral sarcoma 11.7

Graphical network of the top 20 diseases related to Cerebritis:



Diseases related to Cerebritis

Symptoms & Phenotypes for Cerebritis

MGI Mouse Phenotypes related to Cerebritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 8.8 PRLR SETD1A SETD2

Drugs & Therapeutics for Cerebritis

Drugs for Cerebritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Fibrinolytic Agents Phase 2
2 Plasminogen Phase 2
3 Tissue Plasminogen Activator Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase
1 Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation Completed NCT00224770 Phase 2
2 A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes Terminated NCT01251913

Search NIH Clinical Center for Cerebritis

Genetic Tests for Cerebritis

Anatomical Context for Cerebritis

MalaCards organs/tissues related to Cerebritis:

39
Brain, Cortex, Endothelial, Testes, Bone, Heart, T Cells

Publications for Cerebritis

Articles related to Cerebritis:

(show top 50) (show all 14125)
id Title Authors Year
1
Cerebral hemodynamics and pseudo-continuous arterial spin labeling considerations in adults with sickle cell anemia. ( 28052565 )
2017
2
Tumoral Presentation of Homonymous Hemianopia and Prosopagnosia in Cerebral Amyloid Angiopathy-Related Inflammation. ( 28187081 )
2017
3
Extra-axial ependymoma of the cerebral convexity: A very rare intracranial adult tumor. ( 28059629 )
2017
4
Bilateral globus pallidus internus deep brain stimulation for dyskinetic cerebral palsy supports success of cochlear implantation in a 5-year old ex-24A week preterm twin with absent cerebellar hemispheres. ( 28017556 )
2017
5
Relationship between white matter connectivity loss and cortical thinning in cerebral amyloid angiopathy. ( 28462514 )
2017
6
Cortical superficial siderosis and first-ever cerebral hemorrhage in cerebral amyloid angiopathy. ( 28356458 )
2017
7
Postconditioning-induced neuroprotection, mechanisms and applications in cerebral ischemia. ( 28087295 )
2017
8
Long-term outcomes of allogeneic haematopoietic stem cell transplantation for adult cerebral X-linked adrenoleukodystrophy. ( 28375456 )
2017
9
Focusing on Participation: A Commentary on "Current Rehabilitation Practices for Children with Cerebral Palsy: Focus and Gaps". ( 28080172 )
2017
10
Body composition, diet, and physical activity: a longitudinal cohort study in preschoolers with cerebral palsy. ( 28077375 )
2017
11
Visuospatial Functioning in Cerebral Amyloid Angiopathy: A Pilot Study. ( 28222510 )
2017
12
Inhibition of DPP-4 Activity and Neuronal Atrophy with Genistein Attenuates Neurological Deficits Induced by Transient Global Cerebral Ischemia and Reperfusion in Streptozotocin-Induced Diabetic Mice. ( 28091829 )
2017
13
Activation of Cerebral X-linked Adrenoleukodystrophy After Head Trauma. ( 28534457 )
2017
14
Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature. ( 27812816 )
2017
15
Impact of aberrant cerebral perfusion on resting-state functional MRI: A preliminary investigation of Moyamoya disease. ( 28441445 )
2017
16
Predictors and mechanisms of epilepsy occurrence in cerebral gliomas: What to look for in clinicopathology. ( 28087392 )
2017
17
Erratum to: Convexity subarachnoid haemorrhage has a high risk of intracerebral haemorrhage in suspected cerebral amyloid angiopathy. ( 28243752 )
2017
18
Biofeedback interventions for people with cerebral palsy: a systematic review protocol. ( 28086958 )
2017
19
Taxifolin inhibits amyloid-I^ oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy. ( 28376923 )
2017
20
Standing activity intervention and motor function in a young child with cerebral palsy: A case report. ( 28071965 )
2017
21
Britanin Ameliorates Cerebral Ischemia-Reperfusion Injury by Inducing the Nrf2 Protective Pathway. ( 28186440 )
2017
22
Discrimination Between Patients With Alzheimer Disease and Healthy Subjects Using Layer Analysis of Cerebral Blood Flow and Xenon Solubility Coefficient in Xenon-Enhanced Computed Tomography. ( 28505626 )
2017
23
Fatal Cerebral Edema With Status Epilepticus in Children With Dravet Syndrome: Report of 5 Cases. ( 28330972 )
2017
24
Stability of the Gross Motor Function Classification System in children and adolescents with cerebral palsy: a retrospective cohort registry study. ( 28083887 )
2017
25
Family adaptation to cerebral palsy in adolescents: A European multicenter study. ( 28087202 )
2017
26
Histological and immunohistochemical characteristics of cerebral amyloid angiopathy in elderly dogs. ( 27669976 )
2017
27
Cerebral Venous Sinus Thrombosis Presenting Feature of Systemic Lupus Erythematosus. ( 28065614 )
2017
28
Reliability and sources of variation of the ABILHAND-Kids questionnaire in children with cerebral palsy. ( 28068864 )
2017
29
Heat shock protein expression in cerebral X-linked adrenoleukodystrophy reveals astrocyte stress prior to myelin loss. ( 28319253 )
2017
30
Pediatric cerebral sinovenous thrombosis following cranial surgery. ( 28091816 )
2017
31
Neurocognitive Performance After Cerebral Revascularization in Adult Moyamoya Disease. ( 28487332 )
2017
32
Cortical bone deficit and fat infiltration of bone marrow and skeletal muscle in ambulatory children with mild spastic cerebral palsy. ( 27732905 )
2017
33
Identification of neurovascular changes associated with cerebral amyloid angiopathy from subject-specific hemodynamic response functions. ( 28145796 )
2017
34
Cerebral amyloid angiopathy: a long-term consequence of traumatic brain injury? ( 27796651 )
2017
35
Intraarterial route increases the risk of cerebral lesions after mesenchymal cell administration in animal model of ischemia. ( 28091591 )
2017
36
Emerging concepts in sporadic cerebral amyloid angiopathy. ( 28334869 )
2017
37
Convexity subarachnoid haemorrhage has a high risk of intracerebral haemorrhage in suspected cerebral amyloid angiopathy. ( 28154972 )
2017
38
Acute Cerebral Artery Occlusion by a Calcified Embolus with False Patency Sign on Computed Tomographic Angiography. ( 27789151 )
2017
39
Cerebral amyloid angiopathy in Down syndrome and sporadic and autosomal-dominant Alzheimer's disease. ( 28463681 )
2017
40
Persistent Hypotension and Cerebral Swelling Resulting From Mesenteric Traction Syndrome After Omental-to-Pial Pedicle Flap Transfer in a Young Woman With Refractory Moyamoya Disease: A Case Report. ( 28520567 )
2017
41
Patterns of retinal hemorrhage associated with pediatric cerebral sinovenous thrombosis. ( 28087346 )
2017
42
Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease. ( 28515434 )
2017
43
Proteinuria as an independent risk factor for contrast-induced acute kidney injury and mortality in patients with stroke undergoing cerebral angiography. ( 27106594 )
2017
44
Sushi repeat-containing protein 1: a novel disease-associated molecule in cerebral amyloid angiopathy. ( 28478503 )
2017
45
Stable cognitive functioning with improved perceptual reasoning in children with dyskinetic cerebral palsy and other secondary dystonias after deep brain stimulation. ( 27836441 )
2017
46
Predictors of early in-hospital death after decompressive craniectomy in swollen middle cerebral artery infarction. ( 27942881 )
2017
47
The use of therapeutic magnesium for neuroprotection during global cerebral ischemia associated with cardiac arrest and cardiac surgery in adults: a systematic review. ( 28085730 )
2017
48
Plantar flexor muscle weakness and fatigue in spastic cerebral palsy patients. ( 28064025 )
2017
49
Erratum to: Cerebral amyloid angiopathy in a young man with a history of traumatic brain injury: a case report and review of the literature. ( 27913939 )
2017
50
Artesunate and erythropoietin synergistically improve the outcome of experimental cerebral malaria. ( 28531845 )
2017

Variations for Cerebritis

Expression for Cerebritis

Search GEO for disease gene expression data for Cerebritis.

Pathways for Cerebritis

Pathways related to Cerebritis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.63 SETD1A SETD2
2
Show member pathways
11.31 SETD1A SETD2
3 10.84 CXCL5 IRAK4
4 10.39 SETD1A SETD2

GO Terms for Cerebritis

Biological processes related to Cerebritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 methylation GO:0032259 9.16 SETD1A SETD2
2 histone lysine methylation GO:0034968 8.96 SETD1A SETD2
3 neutrophil mediated immunity GO:0002446 8.62 CXCL5 IRAK4

Molecular functions related to Cerebritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 methyltransferase activity GO:0008168 8.96 SETD1A SETD2
2 histone-lysine N-methyltransferase activity GO:0018024 8.62 SETD1A SETD2

Sources for Cerebritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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