MCID: CRB009
MIFTS: 56

Cerebritis malady

Summaries for Cerebritis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Cerebritis is an infection of the brain that normally leads to the formation of an abscess within the... more...

MalaCards: Cerebritis is related to alzheimer's disease and cadasil. An important gene associated with Cerebritis is APP (amyloid beta (A4) precursor protein), and among its related pathways is A-beta Plaque Formation & APP Metabolism . The compound methionine sulfoxide have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and endothelial, and related mouse phenotypes are normal and cardiovascular system.

Aliases & Classifications for Cerebritis

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8Disease Ontology, 60UMLS, 39NCIt
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Aliases & Descriptions:

cerebritis 8 60


External Ids:

Disease Ontology8 DOID:3431
NCIt39 C27199

Related Diseases for Cerebritis

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17GeneCards, 18GeneDecks
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Diseases related to Cerebritis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 1550)
idRelated DiseaseScoreTop Affiliating Genes
1alzheimer's disease31.1NOTCH3, APP, CST3
2cadasil30.9NOTCH3
3stroke, ischemic30.9CCM2, KRIT1, NOTCH3
4vascular disease30.7KRIT1, PDCD10, CCM2
5cerebral cavernous malformation, familial30.6KRIT1, PDCD10, CCM2
6cerebral cavernous malformation30.5KRIT1, PDCD10, CCM2
7cerebrovascular disease30.5NOTCH3, KRIT1, APP, CST3
8vascular dementia30.4NOTCH3
9prion disease30.1CST3, APP
10cerebral cavernous malformations-130.1KRIT1
11klippel-trenaunay syndrome30.0KRIT1, PDCD10, CCM2
12familial cerebral cavernous malformation 229.7CCM2
13hemorrhage, intracerebral29.6CST3, APP, KRIT1
14creutzfeldt-jakob syndrome29.4APP, CST3
15cerebral palsy11.1
16ischemia11.1
17cerebral artery occlusion11.0
18cerebral malaria11.0
19malaria11.0
20cerebral amyloid angiopathy11.0
21spastic cerebral palsy10.9
22transient cerebral ischemia10.9
23neuronitis10.8
24middle cerebral artery infarction10.8
25cerebral atherosclerosis10.7
26atherosclerosis10.7
27hypertension10.7
28cerebral lymphoma10.7
29cerebral arterial disease10.7
30dementia10.7
31arteriovenous malformation10.6
32carotid artery occlusion10.6
33arteriosclerosis10.6
34meningitis10.6
35brain edema10.6
36moyamoya disease10.6
37cerebral degeneration10.6
38amyloidosis10.6
39hydrocephalus10.5
40plasmodium malariae malaria10.5
41vasculitis10.5
42phaeohyphomycosis10.5
43cerebral arteritis10.5
44adrenoleukodystrophy10.5
45migraine10.5
46hepatitis10.5
47multiple sclerosis10.4
48carotid stenosis10.4
49intracranial aneurysm10.4
50cerebral neuroblastoma10.4

Graphical network of the top 20 diseases related to Cerebritis:



Diseases related to cerebritis

Clinical Features for Cerebritis

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Drugs & Therapeutics for Cerebritis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Cerebritis

Drug clinical trials:

Search ClinicalTrials for Cerebritis

Search NIH Clinical Center for Cerebritis

Search CenterWatch for Cerebritis

Genetic Tests for Cerebritis

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Anatomical Context for Cerebritis

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32MalaCards
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MalaCards organs/tissues related to Cerebritis:

32
Brain, Cortex, Endothelial, Testes, Bone, Heart, Liver, Pituitary, T cells, Smooth muscle, B cells, Kidney, Bone marrow, Spinal cord, Skin, Thyroid, Cerebellum, Eye, Temporal lobe, Monocytes, Hypothalamus, Thalamus, Retina, Lung, Pineal, Skeletal muscle, Colon, Globus pallidus, Amygdala, Tongue, Spleen, Whole blood, Breast, Pons, Caudate nucleus, Prefrontal cortex, Olfactory bulb, Myeloid, Nk cells, Parietal lobe, Fetal brain, Occipital lobe, Ovary, Dorsal root ganglion, Lymph node, Salivary gland, Adrenal gland, Prostate, Cingulate cortex, Trigeminal ganglion

Animal Models for Cerebritis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Cerebritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000287312.3CCM2, PDCD10, APP, KNDC1, RMDN3, NOTCH3
2MP:000538512.3CCM2L, CCM2, PDCD10, CST3, BAP1, KRIT1
3MP:000536912.2NOTCH3, CCM2L, CCM2, PDCD10, CST3, APP

Publications for Cerebritis

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50PubMed
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Articles related to Cerebritis:

(show top 50)    (show all 12038)
idTitleAuthorsYear
1
Modulation of cerebral malaria by curcumin as an adjunctive therapy. (23906771)
2013
2
Unusual cerebral vascular prion protein amyloid distribution in scrapie-infected transgenic mice expressing anchorless prion protein. (24252347)
2013
3
Gait patterns in twins with cerebral palsy: similarities and development over time after multilevel surgery. (23475009)
2013
4
Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus. (23266514)
2013
5
A case of cerebral sinus venous thrombosis resulting in mortality in severe preeclamptic pregnant woman. (23509646)
2013
6
Proteomic analysis of leptomeningeal amyloid fibril extracts of cerebral amyloid angiopathy (CAA) patients with or without corticosteroid therapy. (23879185)
2013
7
Developmental trajectories of social participation in individuals with cerebral palsy: a multi-centre longitudinal study. (24359158)
2013
8
Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger. (23149557)
2013
9
Convergent and Divergent Pathways Decoding Hierarchical Additive Mechanisms in Treating Cerebral Ischemia-Reperfusion Injury. (24351012)
2013
10
One hundred ten days of extracorporeal membrane oxygenation in a young woman with postpartum cerebral venous thrombosis and acute respiratory distress syndrome. (22917818)
2012
11
Thunderclap headache as the primary clinical feature of a supratentorial embolic cerebral infarct. (22207313)
2012
12
Neurologic outcomes in retinopathy-negative cerebral malaria survivors. (22914840)
2012
13
Neuronal damage using fluoro-jade B histofluorescence and gliosis in the striatum after various durations of transient cerebral ischemia in gerbils. (22219128)
2012
14
Clinical significance of anti-annexin V antibody in acute cerebral ischemia. (21450308)
2011
15
Association of ADAMTS13 polymorphism with cerebral malaria. (22168261)
2011
16
Key compound groups for the neuroprotective effect of roots of Polygonum cuspidatum on transient middle cerebral artery occlusion in Sprague-Dawley rats. (20645208)
2010
17
Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-iomazenil uptake in the cerebral cortex: a SPECT study. (20130400)
2010
18
APOE epsilon4 genotype and longitudinal changes in cerebral blood flow in normal aging. (20065135)
2010
19
Crystal structure of human programmed cell death 10 complexed with inositol-(1,3,4,5)-tetrakisphosphate: a novel adaptor protein involved in human cerebral cavernous malformation. (20682288)
2010
20
Platelet-endothelial cell interactions in cerebral malaria: the end of a cordial understanding. (19967139)
2009
21
Effect of seat surface inclination on postural stability and forward reaching efficiency in children with spastic cerebral palsy. (19647395)
2009
22
Effects of recombinant human erythropoietin on neuropathic pain and cerebral expressions of cytokines and nuclear factor-kappa B. (19440808)
2009
23
Treatment with the glycogen synthase kinase-3beta inhibitor, TDZD-8, affects transient cerebral ischemia/reperfusion injury in the rat hippocampus. (18323734)
2008
24
Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus. (18426823)
2008
25
Deep hypothermic circulatory arrest for complex cerebral aneurysms: lessons learned. (18695551)
2008
26
T2*-weighted MR images of a patient with familial cerebral cavernous malformation. (17443056)
2007
27
Plasmodium falciparum delayed cerebellar ataxia and late cerebral malaria. (15937892)
2005
28
Antifungal therapy of experimental cerebral phaeohyphomycosis due to Cladophialophora bantiana. (15855484)
2005
29
Expression of phosphorylation of N-methyl-D-aspartate receptor subunits during graded hypoxia in the cerebral cortex of newborn piglets. (14631158)
2004
30
The angiotensin II type 1-receptor blocker candesartan increases cerebral blood flow, reduces infarct size, and improves neurologic outcome after transient cerebral ischemia in rats. (15087716)
2004
31
Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets. (15347772)
2004
32
Haematopoietic stem cell transplantation in 12 patients with cerebral X-linked adrenoleukodystrophy. (12486501)
2003
33
Cerebral vascular abnormalities in a murine model of hereditary hemorrhagic telangiectasia. (12624308)
2003
34
Nestin and small heat shock protein expression on reactive astrocytes and endothelial cells in cerebral abscess. (12354635)
2002
35
T-786C polymorphism in endothelial NO synthase gene affects cerebral circulation in smokers: possible gene-environmental interaction. (11950698)
2002
36
Improved neuroprotection with hypothermia delayed by 6 hours following cerebral hypoxia-ischemia in the 14-day-old rat. (11756634)
2002
37
Functional involvement of cerebral diazepam binding inhibitor (DBI) in the establishment of drug dependence]. (11288485)
2001
38
Actions of Ginkgo Biloba related to potential utility for the treatment of conditions involving cerebral hypoxia. (10983836)
2000
39
Plasma beta-amyloid peptide, transforming growth factor-beta 1, and risk for cerebral amyloid angiopathy. (10818500)
2000
40
Interactions between vasoconstrictors in isolated human cerebral arteries. (9248594)
1997
41
Dyskinetic cerebral palsy and birth asphyxia. (8157150)
1994
42
Cellular and substrate adhesion molecules (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease. (7515758)
1994
43
Glutamate increases tau phosphorylation in primary neuronal cultures from fetal rat cerebral cortex. (7914466)
1994
44
Long-term observations in gerbil brain following transient cerebral ischemia: autoradiographic and histological study. (8272028)
1993
45
Effects of indeloxazine on hippocampal CA1 pyramidal cell damage following transient cerebral ischemia in the gerbil. (8474628)
1993
46
Primary cerebral neuroblastoma. (6716155)
1984
47
DEM and cerebral arteriosclerosis. (6875159)
1983
48
Cerebral gigantism. Review of the literature and report of one case]. (12259613)
1976
49
Cerebral medulloepithelioma. Case report. (6065130)
1967
50
Misinterpretation of mirror image of self in presenile cerebral atrophy. (18881936)
1948

Genetic Variations for Cerebritis

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Expression for genes affiliated with Cerebritis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cerebritis

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Pathways for genes affiliated with Cerebritis

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52R&D Systems
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Pathways related to Cerebritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
111.0APP, CST3

Compounds for genes affiliated with Cerebritis

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44Novoseek, 11DrugBank, 24HMDB
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Compounds related to Cerebritis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1methionine sulfoxide44 11 2413.0KRIT1, APP

GO Terms for genes affiliated with Cerebritis

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16Gene Ontology
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Molecular functions related to Cerebritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00551513.6TSC22D1, CCM2, PDCD10, CST3, APP, ITM2C
2beta-amyloid bindingGO:00154011.0ITM2C, CST3

Products for genes affiliated with Cerebritis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cerebritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet