Aliases & Classifications for Cerebritis

MalaCards integrated aliases for Cerebritis:

Name: Cerebritis 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3431
NCIt 46 C27199
UMLS 69 C0742115

Summaries for Cerebritis

MalaCards based summary : Cerebritis is related to cerebral palsy and cerebral amyloid angiopathy, cst3-related. An important gene associated with Cerebritis is WAC (WW Domain Containing Adaptor With Coiled-Coil), and among its related pathways/superpathways are PKMTs methylate histone lysines and Pertussis. The drugs Fibrinolytic Agents and Plasminogen have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and endothelial.

Wikipedia : 72 Cerebritis is an infection of the brain that normally leads to the formation of an abscess within the... more...

Related Diseases for Cerebritis

Diseases related to Cerebritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1952)
# Related Disease Score Top Affiliating Genes
1 cerebral palsy 12.5
2 cerebral amyloid angiopathy, cst3-related 12.4
3 cerebral cavernous malformations 12.3
4 cerebral amyloid angiopathy, app-related 12.3
5 cerebral palsy, ataxic, autosomal recessive 12.3
6 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 12.3
7 cerebral cavernous malformations 2 12.2
8 transient cerebral ischemia 12.2
9 cerebral cavernous malformations 3 12.2
10 cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 12.2
11 vasculopathy, retinal, with cerebral leukodystrophy 12.2
12 cerebral atrophy 12.2
13 cerebral atherosclerosis 12.2
14 spastic diplegia cerebral palsy 12.2
15 cerebral aneurysms 12.2
16 cerebral hypoxia 12.1
17 dyskinetic cerebral palsy 12.1
18 cerebral folate deficiency 12.1
19 reversible cerebral vasoconstriction syndrome 12.1
20 cerebral arteriosclerosis 12.1
21 cerebral amyloid angiopathy, itm2b-related, 1 12.1
22 spastic cerebral palsy 12.1
23 cerebral ventricle cancer 12.1
24 cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome 12.1
25 keratosis follicularis, dwarfism, and cerebral atrophy 12.1
26 hereditary cerebral amyloid angiopathy 12.1
27 cerebral amyloid angiopathy, itm2b-related, 2 12.1
28 cerebral creatine deficiency syndrome 1 12.0
29 cerebral palsy, spastic quadriplegic, 1 12.0
30 mixed cerebral palsy 12.0
31 microcephaly, progressive, with seizures and cerebral and cerebellar atrophy 12.0
32 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2 12.0
33 cerebral creatine deficiency syndrome 3 12.0
34 cerebral arteritis 12.0
35 deafness, dystonia, and cerebral hypomyelination 12.0
36 cerebral palsy, spastic quadriplegic, 2 12.0
37 neurodegeneration due to cerebral folate transport deficiency 12.0
38 middle cerebral artery infarction 11.9
39 cerebral creatine deficiency syndrome 2 11.9
40 childhood-onset cerebral x-linked adrenoleukodystrophy 11.9
41 lymphedema and cerebral arteriovenous anomaly 11.9
42 cerebral palsy, spastic quadriplegic, 3 11.9
43 cerebral artery occlusion 11.9
44 cerebral lymphoma 11.9
45 malaria 11.9
46 posterior cerebral artery infarction 11.9
47 cerebral gigantism jaw cysts 11.9
48 anterior cerebral artery infarction 11.9
49 cerebral meningioma 11.9
50 cerebral arterial disease 11.9

Graphical network of the top 20 diseases related to Cerebritis:



Diseases related to Cerebritis

Symptoms & Phenotypes for Cerebritis

Drugs & Therapeutics for Cerebritis

Drugs for Cerebritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Fibrinolytic Agents Phase 2
2 Plasminogen Phase 2
3 Tissue Plasminogen Activator Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation Completed NCT00224770 Phase 2 MIS+Cathflo Activase (drug)
2 A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes Terminated NCT01251913

Search NIH Clinical Center for Cerebritis

Genetic Tests for Cerebritis

Anatomical Context for Cerebritis

MalaCards organs/tissues related to Cerebritis:

38
Brain, Cortex, Endothelial, Testes, Bone, Heart, Liver

Publications for Cerebritis

Articles related to Cerebritis:

(show top 50) (show all 14787)
# Title Authors Year
1
Increasing cerebral blood flow reduces the severity of central sleep apnea at high altitude. ( 29389246 )
2018
2
Programmed Cell Death Ligand 1-Induced Coma From Diffuse Cerebritis. ( 29016224 )
2018
3
Cerebral pseudotumor as the first manifestation of POEMS syndrome: A case report. ( 29319491 )
2018
4
Preventive Effects of Resveratrol on Endocannabinoid System and Synaptic Protein Modifications in Rat Cerebral Cortex Challenged by Bilateral Common Carotid Artery Occlusion and Reperfusion. ( 29385102 )
2018
5
A heel-strike real-time auditory feedback device to promote motor learning in children who have cerebral palsy: a pilot study to test device accuracy and feasibility to use a music and dance-based learning paradigm. ( 29423260 )
2018
6
The degree of leukoaraiosis predicts clinical outcomes and prognosis in patients with middle cerebral artery occlusion after intravenous thrombolysis. ( 29288062 )
2018
7
A novel CCM1/KRIT1 heterozygous deletion mutation (c.1919delT) in a Chinese family with familial cerebral cavernous malformation. ( 29169046 )
2018
8
Childhood cerebral X-linked adrenoleukodystrophy with atypical neuroimaging abnormalities and a novel mutation. ( 29386416 )
2018
9
Deep brain stimulation for dystonia due to cerebral palsy: A review. ( 29396170 )
2018
10
Progression of vasogenic edema induced by activated microglia under permanent middle cerebral artery occlusion. ( 29353043 )
2018
11
Cognitive functioning in dyskinetic cerebral palsy: Its relation to motor function, communication and epilepsy. ( 29108712 )
2018
12
The treatment of femoral fractures in children with cerebral palsy. ( 29446787 )
2018
13
Deep brain stimulation in cerebral palsy: Time for dynamism in a static encephalopathy. ( 29447767 )
2018
14
Management of brothers with haemophilia A and familial cerebral cavernous malformations. ( 29418046 )
2018
15
Relationship between radiographic patella-alta pathology and walking dysfunction in children with bilateral spastic Cerebral Palsy. ( 29149666 )
2018
16
Comparison of calf muscle architecture between Asian children with spastic cerebral palsy and typically developing peers. ( 29304114 )
2018
17
Diagnosis and Treatment of Cerebral Venous Thrombosis: A Review. ( 29441008 )
2018
18
Case Report: A Case of Severe Cerebral Malaria Managed with Therapeutic Hypothermia and Other Modalities for Brain Edema. ( 29405103 )
2018
19
Endovascular treatment of cerebral aneurysm after renal transplantation in polycystic kidney disease. ( 29444616 )
2018
20
Licorice Pretreatment Protects Against Brain Damage Induced by Middle Cerebral Artery Occlusion in Mice. ( 29341803 )
2018
21
Doxycycline inhibits experimental cerebral malaria by reducing inflammatory immune reactions and tissue-degrading mediators. ( 29438386 )
2018
22
Renal histopathological findings of retinal vasculopathy with cerebral leukodystrophy. ( 29322432 )
2018
23
Goreisan Prevents Brain Edema after Cerebral Ischemic Stroke by Inhibiting Aquaporin 4 Upregulation in Mice. ( 29153303 )
2018
24
Contribution of perinatal conditions to cerebral palsy in Uganda. ( 29433660 )
2018
25
Cough Headache Presenting with Reversible Cerebral Vasoconstriction Syndrome: A Case Report. ( 29321411 )
2018
26
Cyclic Mechanical Stretch Induced Smooth Muscle Cell Changes in Cerebral Aneurysm Progress by Reducing Collagen Type IV and Collagen Type VI Levels. ( 29439246 )
2018
27
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease. ( 29170092 )
2018
28
Anticoagulants Resumption after Warfarin-Related Intracerebral Haemorrhage: The Multicenter Study on Cerebral Hemorrhage in Italy (MUCH-Italy). ( 29433151 )
2018
29
Bike skills training for children with cerebral palsy: protocol for a randomised controlled trial. ( 29431140 )
2018
30
Ethnic Differences in Intracranial Artery Tortuosity: A Possible Reason for Different Locations of Cerebral Atherosclerosis. ( 29402073 )
2018
31
Long-term treadmill exercise improves memory impairment through restoration of decreased synaptic adhesion molecule 1/2/3 induced by transient cerebral ischemia in the aged gerbil hippocampus. ( 29341891 )
2018
32
Effect of target temperature management at 32-34a8^A^C in cardiac arrest patients considering assessment by regional cerebral oxygen saturation: A multicenter retrospective cohort study. ( 29432783 )
2018
33
Mixed-location cerebral hemorrhage/microbleeds: Underlying microangiopathy and recurrence risk. ( 29247070 )
2018
34
Intrathecal baclofen in dyskinetic cerebral palsy: effects on function and activity. ( 29148568 )
2018
35
MicroRNA-149-5p regulates blood-brain barrier permeability after transient middle cerebral artery occlusion in rats by targeting S1PR2 of pericytes. ( 29401609 )
2018
36
Commentary Regarding "Caregiver Perceptions and Health-Related Quality-of-Life Changes in Cerebral Palsy Patients After Spinal Arthrodesis". ( 29438220 )
2018
37
Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study. ( 29427117 )
2018
38
Protective effects of D-Limonene against transient cerebral ischemia in stroke-prone spontaneously hypertensive rats. ( 29399074 )
2018
39
Reduced Intravoxel Incoherent Motion Microvascular Perfusion Predicts Delayed Cerebral Ischemia and Vasospasm After Aneurysm Rupture. ( 29439196 )
2018
40
Hemodynamic characteristics of hyperplastic remodeling lesions in cerebral aneurysms. ( 29338059 )
2018
41
Identification of a candidate enhancer for DMRT3 involved in spastic cerebral palsy pathogenesis. ( 29305858 )
2018
42
Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities. ( 29314393 )
2018
43
Cerebral organoids derived from Sandhoff disease induced pluripotent stem cells exhibit impaired neurodifferentiation. ( 29358305 )
2018
44
Secondary coiling after incomplete surgical clipping of cerebral aneurysms: a rescue strategy or a treatment option for complex cases? Institutional series and systematic review. ( 29417290 )
2018
45
Knee contracture in children with cerebral palsy: association with muscle lengths. ( 29451692 )
2018
46
Phase-contrast MRI versus numerical simulation to quantify hemodynamical changes in cerebral aneurysms after flow diverter treatment. ( 29304062 )
2018
47
Fatal reversible cerebral vasoconstriction syndrome. ( 29406896 )
2018
48
Reversible Parkinsonism and Multiple Cerebral Infarctions after Pulmonary Endarterectomy in a Patient with Antiphospholipid Syndrome. ( 29321405 )
2018
49
Ischemia Reperfusion Injury after Gradual versus Rapid Flow Restoration for Middle Cerebral Artery Occlusion Rats. ( 29374244 )
2018
50
Neuroprotective effect of tanshinone IIA weakens spastic cerebral palsy through inflammation, p38MAPK and VEGF in neonatal rats. ( 29257210 )
2018

Variations for Cerebritis

Expression for Cerebritis

Search GEO for disease gene expression data for Cerebritis.

Pathways for Cerebritis

Pathways related to Cerebritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.31 SETD1A SETD2
2 10.84 CXCL5 IRAK4
3 10.39 SETD1A SETD2

GO Terms for Cerebritis

Biological processes related to Cerebritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 covalent chromatin modification GO:0016569 9.13 SETD1A SETD2 WAC
2 neutrophil mediated immunity GO:0002446 8.62 CXCL5 IRAK4

Molecular functions related to Cerebritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 histone-lysine N-methyltransferase activity GO:0018024 8.62 SETD1A SETD2

Sources for Cerebritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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