MCID: CRV030
MIFTS: 32

Cervical Adenitis malady

Category: Immune diseases
Genes Tissues Related diseases Publications Pathways Drugs

Aliases & Classifications for Cervical Adenitis

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Aliases & Descriptions for Cervical Adenitis:

Name: Cervical Adenitis 10 12
 
Cervical Lymphadenitis 10 65

Classifications:

MalaCards categories:
Anatomical: Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology10 DOID:4637
SNOMED-CT59 3502005
NCIt42 C26937
UMLS65 C0149642

Summaries for Cervical Adenitis

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MalaCards based summary: Cervical Adenitis, also known as cervical lymphadenitis, is related to cervicitis and lymphadenitis. An important gene associated with Cervical Adenitis is IL1B (Interleukin 1 Beta), and among its related pathways are Hematopoietic cell lineage and Pertussis. Affiliated tissues include breast, liver and kidney.

Related Diseases for Cervical Adenitis

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Diseases related to Cervical Adenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1cervicitis10.8
2lymphadenitis10.6
3pharyngitis10.6
4stomatitis10.6
5aphthous stomatitis10.6
6lujo hemorrhagic fever10.4CRP, IL1B
7rhabdoid cancer10.4CRP, IL1B
8dentin caries10.4CRP, IL1B
9alcoholic gastritis10.4CRP, IL1B
10periodic fever, aphthous stomatitis, pharyngitis and adenitis10.3
11lateral sclerosis10.3CRP, IL1B
12cutaneous paget's disease10.3CRP, IL1B
13villoglandular variant cervical mucinous adenocarcinoma10.3CRP, IL1B
14porphyria10.3CRP, IL1B
15funisitis10.3CRP, IL1B
16meningitis10.3CRP, IL1B
17hypoglycemic coma10.3CRP, IL1B
18commensal bacterial infectious disease10.3CRP, IL1B
19cardiac arrest10.3CRP, HSF4
20viral gastritis10.3CRP, IL1B
21rumination disorder10.3CRP, HSF4
22porokeratosis10.3CRP, HSF4
23placental abruption10.3IL1B, MEFV
24glycoproteinosis10.3CRP, IL1B
25multiple sclerosis 510.2MEFV, MVK
26cecum lymphoma10.2CRP, HSF4
27liver leiomyosarcoma10.2CRP, IL1B
28louse-borne relapsing fever10.2MEFV, MVK
29diffuse scleroderma10.2CRP, IL1B
30limited scleroderma10.2CRP, IL1B
31hyperglycemia10.2CRP, IL1B
32dermoid cyst of ovary10.2CRP, MVK
33rhinoscleroma10.2CRP, MEFV
34malignant giant cell tumor of the tendon sheath10.2CRP, IL1B
35diffuse secondary choroid atrophy10.1CRP, MEFV
36amyloidosis beta2m10.1CRP, MEFV
37uterine corpus epithelioid leiomyosarcoma10.1CRP, IL1B
38peripheral artery disease10.1CRP, MEFV
39tinea capitis10.1IL1B, NLRP3
40partial circumpapillary choroid dystrophy10.1CRP, MEFV
41waardenburg syndrome type 410.1IL1B, NLRP3
42heart disease10.1CRP, IL1B
43familial colorectal cancer10.1IL1B, NLRP3
44tuberculoid leprosy10.1CRP, MEFV
45leech infestation10.1CRP, MEFV
46organic acidemia10.1CRP, IL1B
47peripheral retinal degeneration10.1IL1B, NLRP3
48hyper-igd syndrome10.0MVK, NLRP3
49mixed mineral dust pneumoconiosis10.0IL1B, NLRP3
50blepharophimosis10.0CRP, NLRP3

Graphical network of the top 20 diseases related to Cervical Adenitis:



Diseases related to cervical adenitis

Symptoms for Cervical Adenitis

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Drugs & Therapeutics for Cervical Adenitis

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Drugs for Cervical Adenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1BifidobacteriumNutraceuticalPhase 2213
2AcidophilusNutraceuticalPhase 2482

Interventional clinical trials:

idNameStatusNCT IDPhase
1Comparison of Antibiotic Therapy Alone or Combined With Corticosteroids for the Treatment of Nontuberculous Mycobacterial Cervicofacial Lymphadenitis in Children: A Randomized Double-Blind Placebo-Controlled StudyWithdrawnNCT01614977Phase 3
2Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)Not yet recruitingNCT02535962Phase 2
3Ilaris (Canakinumab) in Patient With Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA)Not yet recruitingNCT02775994Phase 1
4Ultrasonographic Differentiation Between Kikuchi's Disease and Lymphoma in Patients With Cervical LymphadenopathyRecruitingNCT01310933
5Clinical Studies of Kikuchi's DiseaseWithdrawnNCT00172445

Search NIH Clinical Center for Cervical Adenitis

Genetic Tests for Cervical Adenitis

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Anatomical Context for Cervical Adenitis

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MalaCards organs/tissues related to Cervical Adenitis:

33
Breast, Liver, Kidney, Prostate, Thyroid, Monocytes, Neutrophil

Animal Models for Cervical Adenitis or affiliated genes

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Publications for Cervical Adenitis

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Articles related to Cervical Adenitis:

(show top 50)    (show all 115)
idTitleAuthorsYear
1
Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) syndrome: analysis of patients from two geographic areas. (27059542)
2016
2
Vitamin D levels and effects of vitamin D replacement in children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. (24746456)
2014
3
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). (25209127)
2014
4
Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system. (24134207)
2013
5
Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. (23983059)
2013
6
Lymph-node-first presentation of Kawasaki disease compared with bacterial cervical adenitis and typical Kawasaki disease. (23305955)
2013
7
Incidence, clinical characteristics and outcome in Norwegian children with periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome; a population-based study. (23106338)
2013
8
A case of resistant adult-onset periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome responsive to anakinra. (22931584)
2012
9
Periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis. (22759839)
2012
10
An eight-month-old child with cervical adenitis. (23997784)
2012
11
Familial cases of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. (21074183)
2011
12
Long-term follow-up of children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. (21798555)
2011
13
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). (20824883)
2010
14
Surgical outcomes and histology findings after tonsillectomy in children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. (20015793)
2010
15
Periodic fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA syndrome) in adults. (18605359)
2008
16
First Canadian Reports of Cervical Adenitis Due to Mycobacterium Malmoense and a 10-year Review of Nontuberculous Mycobacterial Adenitis. (18418488)
2006
17
Streptococcal necrotizing fasciitis with toxic shock syndrome following cervical adenitis. (15302155)
2004
18
Utility of tonsillectomy in 2 patients with the syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis. (12810475)
2003
19
Three cases of atypical mycobacterial cervical adenitis. (12612115)
2003
20
Nontuberculous mycobacterial cervical adenitis: a ten-year retrospective review. (12514400)
2003
21
Cervical adenitis due to Mycobacterium fortuitum in patients with acquired immunodeficiency syndrome. (9427575)
1998
22
Nontuberculous mycobacterial cervical adenitis. (9241478)
1997
23
Cervical adenitis and deep neck infection caused by Streptococcus pneumoniae. (9271051)
1997
24
Application of a PCR based DNA probe for the rapid identification of Mycobacterium malmoense isolated from a case of cervical adenitis. (8945716)
1996
25
Mycobacterial cervical adenitis. (7747914)
1995
26
Cervical adenitis: report of two cases. (8182201)
1994
27
Cervical adenitis caused by Staphylococcus epidermidis. (8432830)
1993
28
Mycobacterium tuberculosis cervical adenitis. Diagnosis and management. (2504530)
1989
29
Neonatal BCG vaccination and mycobacterial cervical adenitis in childhood. (3138802)
1987
30
Childhood cervical adenitis. (6720492)
1984
31
The aetiology of acute cervical adenitis in children: serological and bacteriological studies. (6987407)
1980
32
Suppurative cervical adenitis caused by opportunist mycobacterium. (265175)
1977
33
Letter: Cervical adenitis caused by anaerobic bacteria. (1271177)
1976
34
Staphylococcal cervical adenitis in young infants. (1256958)
1976
35
Diagnosis and management of tuberculous cervical adenitis. (1119991)
1975
36
Corticosteroid therapy of cat-scratch disease. Results of treatment in three cases with rapid resolution of painful lymphadenopathy; Tietze's syndrome and bilateral cervical adenitis as new complications. (13889108)
1962
37
Anonymous mycobacteria in cervical adenitis. (14470217)
1962
38
Infectious mononucleosis presenting as massive tumour of nasopharynx with cervical adenitis. (13588221)
1958
39
Discussion on tuberculous cervical adenitis. (13494514)
1957
40
Tuberculous cervical adenitis in the Bantu. (13122199)
1953
41
Atlas-axis dislocation following cervical adenitis. (12979084)
1952
42
Treatment of tuberculous cervical adenitis with para-aminosalicylic acid. (14833014)
1951
43
X-ray treatment of tuberculous cervical adenitis. (18890868)
1948
44
Tuberculous cervical adenitis. (18904286)
1948
45
Tuberculous cervical adenitis. (18905393)
1948
46
The diagnosis and treatment of tuberculous cervical adenitis. (20248472)
1947
47
EPIDEMIC CERVICAL ADENITIS. (20766948)
1914
48
EPIDEMIC CERVICAL ADENITIS. (20766867)
1913
49
50

Variations for Cervical Adenitis

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Expression for genes affiliated with Cervical Adenitis

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Search GEO for disease gene expression data for Cervical Adenitis.

Pathways for genes affiliated with Cervical Adenitis

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Pathways related to Cervical Adenitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Hematopoietic cell lineage31
9.7FCGR1A, IL1B
2
Pertussis31
9.3IL1B, NLRP3
3
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways57
Show member pathways
8.7IL1B, MEFV, NLRP3

GO Terms for genes affiliated with Cervical Adenitis

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Biological processes related to Cervical Adenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1interleukin-1 beta productionGO:00326119.7IL1B, NLRP3
2inflammatory responseGO:00069548.8CRP, IL1B, NLRP3

Sources for Cervical Adenitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z