MCID: CRV030
MIFTS: 30

Cervical Adenitis malady

Category: Immune diseases

Aliases & Classifications for Cervical Adenitis

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Aliases & Descriptions for Cervical Adenitis:

Name: Cervical Adenitis 11 13
 
Cervical Lymphadenitis 11 66

Classifications:



External Ids:

Disease Ontology11 DOID:4637
SNOMED-CT60 3502005
NCIt43 C26937

Summaries for Cervical Adenitis

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MalaCards based summary: Cervical Adenitis, also known as cervical lymphadenitis, is related to cat-scratch disease and cervicitis. An important gene associated with Cervical Adenitis is IL1B (Interleukin 1 Beta), and among its related pathways are Hematopoietic cell lineage and Selenium Pathway. Affiliated tissues include neutrophil, monocytes and tonsil.

Related Diseases for Cervical Adenitis

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Diseases related to Cervical Adenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 101)
idRelated DiseaseScoreTop Affiliating Genes
1cat-scratch disease30.2CRP, IL1B
2cervicitis10.8
3lymphadenitis10.7
4pharyngitis10.6
5stomatitis10.6
6aphthous stomatitis10.6
7midline interhemispheric variant of holoprosencephaly10.4CRP, IL1B
8cartilage disease10.4CRP, IL1B
9conventional leiomyosarcoma10.4CRP, IL1B
10lung occult adenocarcinoma10.4CRP, IL1B
11kidney rhabdoid cancer10.4CRP, IL1B
12pernicious anemia10.4CRP, IL1B
13paraneoplastic polyneuropathy10.4CRP, IL1B
14malignant gastric granular cell tumor10.4CRP, FCGR1A
15periodic fever, aphthous stomatitis, pharyngitis and adenitis10.3
16cervix erosion10.3CRP, IL1B
17intestinal variant cervical mucinous adenocarcinoma10.3CRP, IL1B
18neonatal period electroclinical syndrome10.3CRP, IL1B
19porokeratosis 3, disseminated superficial actinic10.3CRP, MVK
20cutaneous porphyria10.3CRP, IL1B
21spondylolysis10.3CRP, IL1B
22diphtheria10.3CRP, IL1B
23mononeuritis of lower limb10.3CRP, IL1B
24lymphopenia10.3CRP, IL1B
25spinal canal and spinal cord meningioma10.3CRP, IL1B
26mandibular cancer10.3CRP, IL1B
27sternum lymphoma10.3CRP, IL1B
28inguinal hernia10.3CRP, HSF4
29pulmonary systemic sclerosis10.3CRP, IL1B
30hepatic vein thrombosis10.2CRP, HSF4
31malignant giant cell tumor10.2CRP, IL1B
32epidural spinal canal meningioma10.2CRP, HSF4
33hemorrhagic fever with renal syndrome10.2CRP, IL1B
34multiple sclerosis 510.2MEFV, MVK
35lung hilum cancer10.2CRP, IL1B
36xanthomatosis10.2CRP, IL1B
37rectum leiomyosarcoma10.2CRP, IL1B
38cryoglobulinemia10.2CRP, IL1B
39lemierre's syndrome10.2CRP, MEFV
40atypical follicular adenoma10.2CRP, IL1B
41acquired thrombocytopenia10.1CRP, MEFV
42polyarteritis nodosa10.1CRP, MEFV
43chromoblastomycosis10.1CRP, MEFV
44laryngeal tuberculosis10.1CRP, IL1B
45pyrimidine metabolic disorder10.1CRP, MEFV
46lymphocele10.1IL1B, NLRP3
47warm antibody hemolytic anemia10.1IL1B, NLRP3
48central gyrate choroidal dystrophy10.1CRP, MEFV
49familial dupuytren contracture10.1IL1B, NLRP3
50perianal skin paget's disease10.1CRP, IL1B

Graphical network of the top 20 diseases related to Cervical Adenitis:



Diseases related to cervical adenitis

Symptoms for Cervical Adenitis

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Drugs & Therapeutics for Cervical Adenitis

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Drugs for Cervical Adenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1BifidobacteriumNutraceuticalPhase 2220
2ACIDOPHILUSNutraceuticalPhase 2502

Interventional clinical trials:

idNameStatusNCT IDPhase
1Comparison of Antibiotic Therapy Alone or Combined With Corticosteroids for the Treatment of Nontuberculous Mycobacterial Cervicofacial Lymphadenitis in Children: A Randomized Double-Blind Placebo-Controlled StudyWithdrawnNCT01614977Phase 3
2Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)Not yet recruitingNCT02535962Phase 2
3Ilaris (Canakinumab) in Patient With Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA)Not yet recruitingNCT02775994Phase 1
4Ultrasonographic Differentiation Between Kikuchi's Disease and Lymphoma in Patients With Cervical LymphadenopathyRecruitingNCT01310933
5Clinical Studies of Kikuchi's DiseaseWithdrawnNCT00172445

Search NIH Clinical Center for Cervical Adenitis

Genetic Tests for Cervical Adenitis

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Anatomical Context for Cervical Adenitis

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MalaCards organs/tissues related to Cervical Adenitis:

34
Neutrophil, Monocytes, Tonsil, Lymph node

Animal Models for Cervical Adenitis or affiliated genes

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Publications for Cervical Adenitis

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Articles related to Cervical Adenitis:

(show top 50)    (show all 115)
idTitleAuthorsYear
1
Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) syndrome: analysis of patients from two geographic areas. (27059542)
2016
2
Tuberculosis Cervical Adenitis: Management Dilemmas. (27273690)
2016
3
Analysis of the genetic basis of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. (25988833)
2015
4
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). (25209127)
2014
5
Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) Syndrome in Iranian Children First Report of Iranian Periodic Fever and Autoinflammatory Registry (IPFAIR). (25793068)
2014
6
Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system. (24134207)
2013
7
Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. (23983059)
2013
8
Chronic cervical adenitis in an infant born to a woman with discoid lupus. (22438346)
2012
9
Familial cases of periodic fever with aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. (21074183)
2011
10
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA). (20824883)
2010
11
Periodic fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA syndrome) in adults. (18605359)
2008
12
C-reactive protein in the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome. (17937691)
2007
13
First Canadian Reports of Cervical Adenitis Due to Mycobacterium Malmoense and a 10-year Review of Nontuberculous Mycobacterial Adenitis. (18418488)
2006
14
Streptococcal necrotizing fasciitis with toxic shock syndrome following cervical adenitis. (15302155)
2004
15
Three cases of atypical mycobacterial cervical adenitis. (12612115)
2003
16
Nontuberculous mycobacterial cervical adenitis: a ten-year retrospective review. (12514400)
2003
17
Isolation of Mycobacterium bovis from human cases of cervical adenitis in Tanzania: a cause for concern? (11263522)
2001
18
Mycobacterial cervical adenitis in Auckland: diagnosis by fine needle aspirate. (10073157)
1999
19
Cervical adenitis due to Mycobacterium fortuitum in patients with acquired immunodeficiency syndrome. (9427575)
1998
20
Nontuberculous mycobacterial cervical adenitis. (9241478)
1997
21
Cervical adenitis and deep neck infection caused by Streptococcus pneumoniae. (9271051)
1997
22
Mycobacterial cervical adenitis. (7747914)
1995
23
The application of ultrasound criteria for malignancy in differentiating tuberculous cervical adenitis from metastatic nasopharyngeal carcinoma. (7789023)
1995
24
Cervical adenitis: report of two cases. (8182201)
1994
25
Mycobacterial cervical adenitis in children: medical and surgical management. (8261929)
1993
26
Mycobacterium tuberculosis cervical adenitis. Diagnosis and management. (2504530)
1989
27
Persistent cervical adenitis and nasopharyngeal carcinoma in children. (3608553)
1987
28
Childhood cervical adenitis. (6720492)
1984
29
Cervical adenitis in children. (6660369)
1983
30
Suppurative cervical adenitis caused by opportunist mycobacterium. (265175)
1977
31
Letter: Cervical adenitis caused by anaerobic bacteria. (1271177)
1976
32
Diagnosis and management of tuberculous cervical adenitis. (1119991)
1975
33
Treatment of atypical mycobacterial cervical adenitis with rifampin. (803310)
1975
34
Cervical adenitis caused by Mycobacterium chelonei (M. abscessus). (4648525)
1972
35
Cervical adenitis due to acquired tuberculosis, with partial peripheral paralysis of the face in the new-born report of one case. (4969639)
1967
36
Discussion on tuberculous cervical adenitis. (13494514)
1957
37
Discussion on tuberculous cervical adenitis. (13494512)
1957
38
Tuberculous cervical adenitis. (13492603)
1957
39
Nontuberculous acid-fast cervical adenitis in children. (13323042)
1956
40
Tuberculous cervical adenitis in the Bantu. (13122199)
1953
41
Atlas-axis dislocation following cervical adenitis. (12979084)
1952
42
Tumours of the neck with special reference to cervical adenitis of tuberculous origin. (14938594)
1952
43
Paresthesia of the pharynx due to cervical adenitis. (14856489)
1951
44
Acute right cervical adenitis. (15426528)
1950
45
X-ray treatment of tuberculous cervical adenitis. (18890868)
1948
46
Two Cases of Dislocation of the Cervical Spine in Children Caused by Hyperaemic Decalcification of the Vertebrae following Cervical Adenitis. (19991720)
1938
47
Epidemic Cervical Adenitis. (20779861)
1936
48
Cervical Adenitis: The Diagnosis and Treatment of. (20892077)
1924
49
TUBERCULOUS CERVICAL ADENITIS: A STUDY OF THE TUBERCLE BACILLI CULTIVATED FROM FIFTEEN CONSECUTIVE CASES. (19867315)
1910
50
STUDIES IN ATYPICAL FORMS OF TUBERCLE BACILLI ISOLATED DIRECTLY FROM THE HUMAN TISSUES IN CASES OF PRIMARY CERVICAL ADENITIS : WITH SPECIAL REFERENCE TO THE THEOBALD SMITH GLYCERINE BOUILLON REACTION. (19867256)
1909

Variations for Cervical Adenitis

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Expression for genes affiliated with Cervical Adenitis

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Search GEO for disease gene expression data for Cervical Adenitis.

Pathways for genes affiliated with Cervical Adenitis

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GO Terms for genes affiliated with Cervical Adenitis

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Cellular components related to Cervical Adenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1autophagosomeGO:00057769.5IL1B, MEFV

Biological processes related to Cervical Adenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1interleukin-1 beta productionGO:00326119.8IL1B, NLRP3
2negative regulation of inflammatory responseGO:00507289.0MEFV, MVK, NLRP3
3inflammatory responseGO:00069548.1CRP, IL1B, MEFV, NLRP3

Sources for Cervical Adenitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet