MCID: CRV035
MIFTS: 60

Cervical Cancer malady

Cancer diseases, Reproductive diseases categories

Summaries for Cervical Cancer

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MedlinePlus:33 The cervix is the lower part of the uterus, the place where a baby grows during pregnancy. cervical cancer is caused by a virus called hpv. the virus spreads through sexual contact. most women's bodies are able to fight hpv infection. but sometimes the virus leads to cancer. you're at higher risk if you smoke, have had many children, use birth control pills for a long time, or have hiv infection. cervical cancer may not cause any symptoms at first. later, you may have pelvic pain or bleeding from the vagina. it usually takes several years for normal cells in the cervix to turn into cancer cells. your health care provider can find abnormal cells by doing a pap test to examine cells from the cervix. you may also have an hpv test. if your results are abnormal, you may need a biopsy or other tests. by getting regular screenings, you can find and treat any problems before they turn into cancer. treatment may include surgery, radiation therapy, chemotherapy, or a combination. the choice of treatment depends on the size of the tumor, whether the cancer has spread and whether you would like to become pregnant someday. vaccines can protect against several types of hpv, including some that can cause cancer. nih: national cancer institute

MalaCards based summary: Cervical Cancer, also known as cervical carcinoma, is related to oral cancer and stomach cancer. An important gene associated with Cervical Cancer is FGFR3 (fibroblast growth factor receptor 3), and among its related pathways are Angiogenesis and Pathways in cancer. The compounds glyceraldehyde 3-phosphate and paraffin have been mentioned in the context of this disorder. Affiliated tissues include the cervix, cervix and lymph node.

Disease Ontology:9 A female reproductive organ cancer that is located in the cervix.

CDC:4 Cancer is a disease in which cells in the body grow out of control. Cancer is always named for the part of the body where it starts, even if it spreads to other body parts later.

Wikipedia:64 Cervical cancer is a cancer arising from the cervix. It is due to the abnormal growth of cells that have... more...

Description from OMIM:46 603956

Aliases & Classifications for Cervical Cancer

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Cervical Cancer, Aliases & Descriptions:

Name: Cervical Cancer 31 9 11 44 33
Cervical Carcinoma 46 44 61
Carcinoma of the Cervix Uteri 9 61
Neoplasm of Uterine Cervix 9 61
Tumor of the Cervix Uteri 9 61
Carcinoma Cervix Uteri 9 61
Carcinoma of Cervix 9 61
 
Cervix Carcinoma 9 61
Cancer of Cervix 9 23
Uterine Cervical Neoplasm 61
Malignant Neoplasms 61
Cervix Uteri Cancer 9
Cervical Neoplasm 9
Cervix Cancer 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Reproductive diseases


Related Diseases for Cervical Cancer

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Diseases in the Cervical Cancer family:

Cervical Benign Neoplasm

Diseases related to Cervical Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 178)
idRelated DiseaseScoreTop Affiliating Genes
1oral cancer30.4CD82, HIF1A, VEGFC
2stomach cancer30.2FGFR3, CD82, HIF1A, VEGFC
3melanoma30.1VEGFC, HIF1A, MCM3, CD82, FGFR3
4prostate cancer29.9VEGFC, HIF1A, EEF1A1, CD82, FGFR3
5cervicitis11.5
6cervical intraepithelial neoplasia10.8
7endotheliitis10.6
8papilloma10.6
9hypoxia10.6
10cervical adenoid cystic carcinoma10.6
11cervix small cell carcinoma10.5
12cervical endometrioid adenocarcinoma10.5
13cervical clear cell adenocarcinoma10.5
14adenoiditis10.5
15cervical adenosquamous carcinoma10.5
16rare squamous cell carcinoma of the cervix uteri10.5
17poorly differentiated endocrine carcinoma of the cervix uteri10.5
18glassy cell carcinoma of the cervix uteri10.5
19adenoid basal carcinoma of the cervix uteri10.5
20papillary carcinoma of the cervix uteri10.5
21neuroectodermal tumor10.5
22malignant m├╝llerian mixed tumor of the cervix uteri10.5
23malignant peripheral neuroectodermal tumor of the cervix uteri10.5
24malignant germ cell tumor of the cervix uteri10.5
25vaginitis10.4
26adenocarcinoma10.4
27cystic basal cell carcinoma10.3
28verrucous carcinoma10.3
29basal cell carcinoma10.3
30in situ carcinoma10.3
31retinoblastoma10.2
32cervix uteri carcinoma in situ10.2
33colorectal cancer10.2VEGFC, HIF1A, CD82, FGFR3
34lymphedema10.2
35adenosquamous carcinoma10.2
36hiv/aids10.1
37leukemia10.1
38myoma10.1
39herpes simplex10.1
40sarcoma10.1
41nasopharyngitis10.1
42arthritis10.1
43neuroendocrine carcinoma10.1
44septic arthritis10.1
45small cell neuroendocrine carcinoma10.1
46lymphangitis10.1
47keratinizing squamous cell carcinoma10.1
48fibrous histiocytoma10.1
49anal squamous cell carcinoma10.1
50histiocytoma10.1

Graphical network of the top 20 diseases related to Cervical Cancer:



Diseases related to cervical cancer

Symptoms for Cervical Cancer

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Clinical features from OMIM:

603956

Drugs & Therapeutics for Cervical Cancer

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Drug clinical trials:

Search ClinicalTrials for Cervical Cancer

Search NIH Clinical Center for Cervical Cancer

Genetic Tests for Cervical Cancer

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Genetic tests related to Cervical Cancer:

id Genetic test Affiliating Genes
1 Carcinoma of Cervix23

Anatomical Context for Cervical Cancer

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MalaCards organs/tissues related to Cervical Cancer:

32
Cervix, Lymph node, Testes, Uterus, Endothelial, Breast, T cells, Lung, Bone, Colon, Prostate, Nk cells, Bone marrow, Small intestine, Liver, Thyroid, Ovary, Myeloid, Monocytes

FMA organs/tissues related to Cervical Cancer:

15
The cervix

Animal Models for Cervical Cancer or affiliated genes

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Publications for Cervical Cancer

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Articles related to Cervical Cancer:

(show top 50)    (show all 1945)
idTitleAuthorsYear
1
Cytotoxic function of gamma delta (gamma/delta) T cells against pamidronate-treated cervical cancer cells. (24228383)
2013
2
Promoters of and barriers to cervical cancer screening in a rural setting in Tanzania. (24095307)
2013
3
The synthetic flavonoid WYC02-9 inhibits cervical cancer cell migration/invasion and angiogenesis via MAPK14 signaling. (24145114)
2013
4
Women whose cervical intraepithelial neoplasia has been treated or resolved remain at continued high risk for cervical cancer. (23378629)
2013
5
The nuclear protein expression levels of SNAI1 and ZEB1 are involved in the progression and lymph node metastasis of cervical cancer via the epithelial-mesenchymal transition pathway. (23791009)
2013
6
Nogo-B promotes the epithelial-mesenchymal transition in HeLa cervical cancer cells via Fibulin-5. (23042479)
2013
7
Cellular retinol binding protein 1 could be a tumor suppressor gene in cervical cancer. (24040446)
2013
8
Effect of Rac1 downregulation mediated by shRNA on the biological behaviour of human cervical cancer cells. (23760915)
2013
9
Ethics of "standard care" in randomised trials of screening for cervical cancer should not ignore scientific evidence and ground realities. (24152348)
2013
10
Correction: TACC3 Is Essential for EGF-Mediated EMT in Cervical Cancer. (24073191)
2013
11
Mitosis is a source of potential markers for screening and survival and therapeutic targets in cervical cancer. (23405241)
2013
12
Concurrent chemoradiation with weekly gemcitabine and cisplatin for locally advanced cervical cancer. (24175831)
2013
13
Dysregulated expression of both the costimulatory CD28 and inhibitory CTLA-4 molecules in PB T cells of advanced cervical cancer patients suggests systemic immunosuppression related to disease progression. (22094905)
2012
14
The zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-I_B signaling. (23091055)
2012
15
MicroRNA-10a targets CHL1 and promotes cell growth, migration and invasion in human cervical cancer cells. (22634495)
2012
16
Quality of life among Thai women diagnosed with cervical cancer and cervical intraepithelial neoplasia at King Chulalongkorn Memorial Hospital. (21863670)
2011
17
Human papillomavirus's physical state and cyclin A1 promoter methylation in cervical cancer. (21412159)
2011
18
Genetic alterations in the K-Ras gene influence the prognosis in patients with cervical cancer treated by radiotherapy. (21330833)
2011
19
Carbonic anhydrase XII expression is associated with histologic grade of cervical cancer and superior radiotherapy outcome. (21040567)
2010
20
DNA methylation and carcinogenesis of PRDM5 in cervical cancer. (20213097)
2010
21
Immunolabeling of the inhibin-I^A and -I^B subunit in normal and malignant human cervical tissue and cervical cancer cell lines. (21475087)
2010
22
Rate of cervical cancer, severe intraepithelial neoplasia, and adenocarcinoma in situ in primary HPV DNA screening with cytology triage: randomised study within organised screening programme. (20423964)
2010
23
Topoisomerase I deficiency results in chromosomal alterations in cervical cancer cells. (20944095)
2010
24
The role and mechanism of CXCR4 and its ligand SDF-1 in the development of cervical cancer metastasis]. (18851783)
2008
25
Early growth response-1 mediates downregulation of telomerase in cervical cancer. (18460021)
2008
26
Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha. (18559093)
2008
27
Immunohistochemical expression of p16 and herpes simplex virus type 2 in squamous intraepithelial lesions and cervical cancer]. (19142477)
2008
28
Methyl jasmonate induces cell death with mixed characteristics of apoptosis and necrosis in cervical cancer cells. (18599197)
2008
29
Molecular profiling of cervical cancer progression. (17242701)
2007
30
Relationship between the expression of P-glycoprotein, glutathione S-transferase-pi and thymidylate synthase proteins and adenosine triphosphate tumor chemosensitivity assay in cervical cancer]. (17537309)
2007
31
Expression of IP-10 related to angiogenesis in uterine cervical cancers. (17505511)
2007
32
Uncoupling of promoter methylation and expression of Period1 in cervical cancer cells. (17592726)
2007
33
Hypermethylation and loss of heterozygosity of tumor suppressor genes on chromosome 3p in cervical cancer. (17467893)
2007
34
Polymorphic amino acids at codons 9 and 37 of HLA-DQB1 alleles may confer susceptibility to cervical cancer among Chinese women. (16425277)
2006
35
Promoter methylation of p16, DAPK, CDH1, and TIMP-3 genes in cervical cancer: correlation with clinicopathologic characteristics. (16803511)
2006
36
A shift to a peripheral Th2-type cytokine pattern during the carcinogenesis of cervical cancer becomes manifest in CIN III lesions. (16189158)
2005
37
Pro-apoptotic efficiencies of three reconstructed human caspase-8 on cervical cancer cell line HeLa]. (15694025)
2005
38
Prognostic relevance of TGF-beta1 and PAI-1 in cervical cancer. (15386352)
2004
39
Proteomic analysis of antiproliferative effects by treatment of 5-fluorouracil in cervical cancer cells. (15585135)
2004
40
No alteration in NK function or zeta chain expression in NK and T cells of cervical cancer patients. (12694665)
2003
41
Codon 72 polymorphism of p53 in Israeli Jewish cervical cancer patients and healthy women. (12445252)
2002
42
Implication of a reflected image illustration for pelvic lymphadenectomy on uterine cervical cancer with situs inversus totalis. (11855896)
2002
43
Oxidative stress and tumor markers in cervical cancer patients. (14972792)
2002
44
IFNalpha sensitizes ME-180 human cervical cancer cells to TNFalpha-induced apoptosis by inhibiting cytoprotective NF-kappaB activation. (11322949)
2001
45
Cyclooxygenase-2 is overexpressed in human cervical cancer. (11234900)
2001
46
Adenovirus-mediated p21((WAF1/SDII/CIP1)) gene transfer induces apoptosis of human cervical cancer cell lines. (10233960)
1999
47
Mechanisms of arsenic trioxide induced apoptosis of human cervical cancer HeLa cells and protection by Bcl-2. (18726487)
1999
48
Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in uterine cervical cancers. (10098767)
1999
49
A 2-week pretreatment with 13-cis-retinoic acid + interferon-alpha-2a prior to definitive radiation improves tumor tissue oxygenation in cervical cancers. (9830438)
1998
50
A quantitative approach to the loss of heterozygosity in p53 allele on detection of human cervical cancer using a BioImaging Analyzer. (8172533)
1994

Variations for Cervical Cancer

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Clinvar genetic disease variations for Cervical Cancer:

7
id Gene Name Type Significance SNP ID Assembly Location
1FGFR3NM_000142.4(FGFR3): c.746C> G (p.Ser249Cys)single nucleotide variantPathogenicrs121913483GRCh37Chr 4, 1803568: 1803568

Expression for genes affiliated with Cervical Cancer

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LifeMap Discovery
Genes differentially expressed in tissues of Cervical Cancer patients vs. healthy controls: 31 (show all 318)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1KRT1keratin 1Uterus-5.470.000
2KRTDAPkeratinocyte differentiation-associated proteinUterus-4.960.000
3CTHRC1collagen triple helix repeat containing 1Uterus+4.650.000
4TMPRSS11Btransmembrane protease, serine 11BUterus-4.580.000
5CDKN2Acyclin-dependent kinase inhibitor 2AUterus+4.450.000
6CMPK2cytidine monophosphate (UMP-CMP) kinase 2, mitochondrialUterus+4.320.000
7CRNNcornulinUterus-4.250.000
8MALmal, T-cell differentiation proteinUterus-4.210.000
9DSG1desmoglein 1Uterus-4.170.000
10ECT2epithelial cell transforming 2Uterus+4.100.000
11SYCP2synaptonemal complex protein 2Uterus+3.950.000
12HS6ST2heparan sulfate 6-O-sulfotransferase 2Uterus+3.940.000
13KIF14kinesin family member 14Uterus+3.880.000
14IFI44interferon-induced protein 44Uterus+3.880.000
15MMP1matrix metallopeptidase 1 (interstitial collagenase)Uterus+3.830.001
16GREB1growth regulation by estrogen in breast cancer 1Uterus-3.780.000
17KRT17keratin 17Uterus+3.710.000
18SPINK7serine peptidase inhibitor, Kazal type 7 (putative)Uterus-3.700.000
19NUF2NUF2, NDC80 kinetochore complex componentUterus+3.700.000
20NCEH1neutral cholesterol ester hydrolase 1Uterus+3.640.000
21PLSCR1phospholipid scramblase 1Uterus+3.630.000
22E2F7E2F transcription factor 7Uterus+3.620.000
23ANKRD32ankyrin repeat domain 32Uterus+3.610.000
24INHBAinhibin, beta AUterus+3.590.001
25DAPL1death associated protein-like 1Uterus-3.570.000
26KRT4keratin 4Uterus-3.530.000
27SMC4structural maintenance of chromosomes 4Uterus+3.500.000
28CEP55centrosomal protein 55kDaUterus+3.490.000
29LOXlysyl oxidaseUterus+3.480.000
30ANLNanillin, actin binding proteinUterus+3.480.000
31ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)Uterus+3.460.000
32CRISP3cysteine-rich secretory protein 3Uterus-3.460.001
33HELLShelicase, lymphoid-specificUterus+3.440.000
34KRT19keratin 19Uterus+3.440.002
35SPP1secreted phosphoprotein 1Uterus+3.430.000
36CNFNcornifelinUterus-3.420.000
37EPCAMepithelial cell adhesion moleculeUterus+3.390.000
38NDC80NDC80 kinetochore complex componentUterus+3.350.000
39SCDstearoyl-CoA desaturase (delta-9-desaturase)Uterus+3.310.000
40CRCT1cysteine-rich C-terminal 1Uterus-3.310.002
41KRT13keratin 13Uterus-3.300.010
42CDK1cyclin-dependent kinase 1Uterus+3.300.000
43DDIT4DNA-damage-inducible transcript 4Uterus+3.290.000
44C6orf211chromosome 6 open reading frame 211Uterus+3.290.000
45ALOX12arachidonate 12-lipoxygenaseUterus-3.280.000
46ATAD2ATPase family, AAA domain containing 2Uterus+3.270.000
47ZIC2Zic family member 2Uterus+3.260.000
48ARHGAP21Rho GTPase activating protein 21Uterus+3.240.000
49LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homologUterus+3.240.000
50PPIBpeptidylprolyl isomerase B (cyclophilin B)Uterus+3.230.000
51CSTF3cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDaUterus+3.200.000
52TFRCtransferrin receptorUterus+3.190.000
53TOP2Atopoisomerase (DNA) II alpha 170kDaUterus+3.180.000
54S100A8S100 calcium binding protein A8Uterus-3.180.000
55ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)Uterus+3.160.000
56B4GALT4UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4Uterus+3.150.000
57EDN3endothelin 3Uterus-3.150.000
58IL8interleukin 8Uterus+3.140.000
59RAD51AP1RAD51 associated protein 1Uterus+3.120.000
60HNRNPH2heterogeneous nuclear ribonucleoprotein H2 (H')Uterus+3.120.000
61DTLdenticleless E3 ubiquitin protein ligase homolog (Drosophila)Uterus+3.120.000
62NASPnuclear autoantigenic sperm protein (histone-binding)Uterus+3.090.000
63ESRGembryonic stem cell related (non-protein coding)Uterus-3.070.000
64CENPKcentromere protein KUterus+3.060.000
65PLATplasminogen activator, tissueUterus+3.040.000
66SPINK5serine peptidase inhibitor, Kazal type 5Uterus-3.030.000
67TMEFF2transmembrane protein with EGF-like and two follistatin-like domains 2Uterus-3.020.000
68EREGepiregulinUterus-3.020.000
69ISG15ISG15 ubiquitin-like modifierUterus+3.010.001
70KNTC1kinetochore associated 1Uterus+3.010.000
71DMKNdermokineUterus-3.000.000
72RAB21RAB21, member RAS oncogene familyUterus+2.980.000
73FZD6frizzled class receptor 6Uterus+2.980.000
74C11orf80chromosome 11 open reading frame 80Uterus+2.970.000
75CDC7cell division cycle 7Uterus+2.960.000
76BUB1BUB1 mitotic checkpoint serine/threonine kinaseUterus+2.950.000
77PSMB1proteasome (prosome, macropain) subunit, beta type, 1Uterus+2.950.000
78PLOD2procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2Uterus+2.950.000
79CASP8AP2caspase 8 associated protein 2Uterus+2.950.000
80KIF11kinesin family member 11Uterus+2.940.000
81NEK2NIMA-related kinase 2Uterus+2.930.000
82MIS18AMIS18 kinetochore protein AUterus+2.920.000
83MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)Uterus+2.920.000
84ELAVL2ELAV like neuron-specific RNA binding protein 2Uterus+2.920.001
85DONSONdownstream neighbor of SONUterus+2.920.000
86DNAJB11DnaJ (Hsp40) homolog, subfamily B, member 11Uterus+2.920.000
87CHMLchoroideremia-like (Rab escort protein 2)Uterus+2.920.000
88ZNF367zinc finger protein 367Uterus+2.910.000
89SEL1L3sel-1 suppressor of lin-12-like 3 (C. elegans)Uterus+2.910.000
90SLC20A1solute carrier family 20 (phosphate transporter), member 1Uterus+2.890.000
91LAPTM4Blysosomal protein transmembrane 4 betaUterus+2.890.000
92HNRNPMheterogeneous nuclear ribonucleoprotein MUterus+2.880.000
93PEX13peroxisomal biogenesis factor 13Uterus+2.860.000
94APOBEC3Bapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3BUterus+2.860.000
95DSG2desmoglein 2Uterus+2.850.000
96PNNpinin, desmosome associated proteinUterus+2.850.000
97CMTM6CKLF-like MARVEL transmembrane domain containing 6Uterus+2.840.000
98AIDAaxin interactor, dorsalization associatedUterus+2.840.000
99SOD2superoxide dismutase 2, mitochondrialUterus+2.830.001
100HAT1histone acetyltransferase 1Uterus+2.830.000
101PDP1pyruvate dehyrogenase phosphatase catalytic subunit 1Uterus+2.830.000
102KPNA2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)Uterus+2.820.000
103CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)Uterus+2.820.003
104ENDOUendonuclease, polyU-specificUterus-2.820.000
105SNX10sorting nexin 10Uterus+2.810.000
106ILF2interleukin enhancer binding factor 2Uterus+2.810.000
107MBD4methyl-CpG binding domain protein 4Uterus+2.810.000
108UHRF1ubiquitin-like with PHD and ring finger domains 1Uterus+2.810.000
109CENPJcentromere protein JUterus+2.810.000
110CCNE2cyclin E2Uterus+2.810.000
111RASEFRAS and EF-hand domain containingUterus+2.810.000
112AGLamylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferaseUterus+2.800.000
113YES1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1Uterus+2.800.000
114DKC1dyskeratosis congenita 1, dyskerinUterus+2.790.000
115ANKLE2ankyrin repeat and LEM domain containing 2Uterus+2.790.000
116CENPWcentromere protein WUterus+2.790.000
117ARPP19cAMP-regulated phosphoprotein, 19kDaUterus+2.790.000
118IGF2BP3insulin-like growth factor 2 mRNA binding protein 3Uterus+2.790.004
119SRSF10serine/arginine-rich splicing factor 10Uterus+2.780.000
120MYO1Bmyosin IBUterus+2.780.000
121GALNT7polypeptide N-acetylgalactosaminyltransferase 7Uterus+2.780.000
122KLHDC7Bkelch domain containing 7BUterus+2.760.004
123PSMA3proteasome (prosome, macropain) subunit, alpha type, 3Uterus+2.760.000
124HLTFhelicase-like transcription factorUterus+2.760.000
125IFI44Linterferon-induced protein 44-likeUterus+2.760.008
126FNDC3Bfibronectin type III domain containing 3BUterus+2.760.000
127ABCA13ATP-binding cassette, sub-family A (ABC1), member 13Uterus+2.760.010
128MELKmaternal embryonic leucine zipper kinaseUterus+2.750.000
129GNB4guanine nucleotide binding protein (G protein), beta polypeptide 4Uterus+2.750.000
130CASC5cancer susceptibility candidate 5Uterus+2.740.000
131PARP9poly (ADP-ribose) polymerase family, member 9Uterus+2.740.000
132BNC1basonuclin 1Uterus+2.730.003
133HOOK1hook microtubule-tethering protein 1Uterus+2.730.000
134DPY19L1dpy-19-like 1 (C. elegans)Uterus+2.730.000
135SMIM15small integral membrane protein 15Uterus+2.730.000
136SOAT1sterol O-acyltransferase 1Uterus+2.730.000
137SEC23ASec23 homolog A (S. cerevisiae)Uterus+2.720.000
138RMI1RecQ mediated genome instability 1Uterus+2.720.000
139DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 60Uterus+2.720.001
140TXNDC16thioredoxin domain containing 16Uterus+2.720.000
141RAB1ARAB1A, member RAS oncogene familyUterus+2.720.001
142AGPSalkylglycerone phosphate synthaseUterus+2.720.000
143ABRACLABRA C-terminal likeUterus+2.710.000
144LPGAT1lysophosphatidylglycerol acyltransferase 1Uterus+2.710.000
145TOPBP1topoisomerase (DNA) II binding protein 1Uterus+2.710.000
146ACTR2ARP2 actin-related protein 2 homolog (yeast)Uterus+2.710.000
147AVL9AVL9 homolog (S. cerevisiase)Uterus+2.700.000
148KIF23kinesin family member 23Uterus+2.700.000
149SMSspermine synthaseUterus+2.700.000
150FN1fibronectin 1Uterus+2.700.006
151SWAP70SWAP switching B-cell complex 70kDa subunitUterus+2.690.000
152IFIT2interferon-induced protein with tetratricopeptide repeats 2Uterus+2.690.015
153DERL1derlin 1Uterus+2.690.000
154LRIF1ligand dependent nuclear receptor interacting factor 1Uterus+2.690.000
155NETO2neuropilin (NRP) and tolloid (TLL)-like 2Uterus+2.670.000
156ADAM9ADAM metallopeptidase domain 9Uterus+2.670.000
157SBSNsuprabasinUterus-2.670.005
158RFC4replication factor C (activator 1) 4, 37kDaUterus+2.660.000
159SPTSSAserine palmitoyltransferase, small subunit AUterus+2.660.000
160ANP32Eacidic (leucine-rich) nuclear phosphoprotein 32 family, member EUterus+2.660.000
161ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix proteinUterus-2.660.000
162GPD2glycerol-3-phosphate dehydrogenase 2 (mitochondrial)Uterus+2.650.000
163XAF1XIAP associated factor 1Uterus+2.650.000
164SULT1E1sulfotransferase family 1E, estrogen-preferring, member 1Uterus-2.650.000
165TBL1XR1transducin (beta)-like 1 X-linked receptor 1Uterus+2.650.000
166MOB4MOB family member 4, phoceinUterus+2.650.000
167DBF4DBF4 zinc fingerUterus+2.650.000
168HPRT1hypoxanthine phosphoribosyltransferase 1Uterus+2.650.000
169RBM15RNA binding motif protein 15Uterus+2.650.000
170RFC5replication factor C (activator 1) 5, 36.5kDaUterus+2.650.000
171IFI16interferon, gamma-inducible protein 16Uterus+2.640.000
172DKK2dickkopf WNT signaling pathway inhibitor 2Uterus-2.640.001
173HNRNPU-AS1HNRNPU antisense RNA 1Uterus+2.630.000
174FAM199Xfamily with sequence similarity 199, X-linkedUterus+2.630.000
175DLGAP5discs, large (Drosophila) homolog-associated protein 5Uterus+2.620.000
176DCBLD1discoidin, CUB and LCCL domain containing 1Uterus+2.620.000
177ISL1ISL LIM homeobox 1Uterus-2.620.001
178WDHD1WD repeat and HMG-box DNA binding protein 1Uterus+2.620.000
179TCAM1Ptesticular cell adhesion molecule 1, pseudogeneUterus+2.610.001
180CTSVcathepsin VUterus+2.610.000
181DCKdeoxycytidine kinaseUterus+2.600.000
182PMAIP1phorbol-12-myristate-13-acetate-induced protein 1Uterus+2.600.000
183RDH10retinol dehydrogenase 10 (all-trans)Uterus+2.600.002
184RAB2ARAB2A, member RAS oncogene familyUterus+2.600.000
185PRC1protein regulator of cytokinesis 1Uterus+2.590.000
186ABCG1ATP-binding cassette, sub-family G (WHITE), member 1Uterus+2.590.001
187MMP12matrix metallopeptidase 12 (macrophage elastase)Uterus+2.590.009
188CCNL1cyclin L1Uterus+2.580.000
189TNFAIP8tumor necrosis factor, alpha-induced protein 8Uterus+2.570.000
190ITGB6integrin, beta 6Uterus+2.570.001
191KLK11kallikrein-related peptidase 11Uterus-2.570.003
192RHEBRas homolog enriched in brainUterus+2.570.000
193STK38serine/threonine kinase 38Uterus+2.570.000
194TPD52tumor protein D52Uterus+2.560.000
195TDP2tyrosyl-DNA phosphodiesterase 2Uterus+2.560.000
196TRIM2tripartite motif containing 2Uterus+2.550.004
197BUB1BBUB1 mitotic checkpoint serine/threonine kinase BUterus+2.550.000
198ARRDC3arrestin domain containing 3Uterus+2.550.000
199HPS3Hermansky-Pudlak syndrome 3Uterus+2.540.000
200PRKDCprotein kinase, DNA-activated, catalytic polypeptideUterus+2.540.000
201SLC33A1solute carrier family 33 (acetyl-CoA transporter), member 1Uterus+2.540.000
202TNFSF10tumor necrosis factor (ligand) superfamily, member 10Uterus+2.530.001
203FNBP1Lformin binding protein 1-likeUterus+2.530.000
204SLBPstem-loop binding proteinUterus+2.520.000
205PSIP1PC4 and SFRS1 interacting protein 1Uterus+2.520.000
206ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix proteinUterus+2.520.002
207MRPL19mitochondrial ribosomal protein L19Uterus+2.520.000
208ZC3H7Azinc finger CCCH-type containing 7AUterus+2.520.000
209CA2carbonic anhydrase IIUterus+2.510.006
210CPNE8copine VIIIUterus+2.510.000
211HIST1H1Chistone cluster 1, H1cUterus+2.510.000
212CENPAcentromere protein AUterus+2.510.000
213ZBTB38zinc finger and BTB domain containing 38Uterus+2.510.000
214CLIC3chloride intracellular channel 3Uterus-2.510.001
215ARFGAP3ADP-ribosylation factor GTPase activating protein 3Uterus+2.500.000
216AURKAaurora kinase AUterus+2.500.000
217TMEM87Btransmembrane protein 87BUterus+2.500.000
218PPP1R3Cprotein phosphatase 1, regulatory subunit 3CUterus-2.480.001
219RDH12retinol dehydrogenase 12 (all-trans/9-cis/11-cis)Uterus-2.440.000
220DKK3dickkopf WNT signaling pathway inhibitor 3Uterus-2.400.008
221IL1R2interleukin 1 receptor, type IIUterus-2.370.008
222SOSTDC1sclerostin domain containing 1Uterus-2.360.013
223RPL37Aribosomal protein L37aUterus-2.340.000
224CLDN8claudin 8Uterus-2.340.006
225ESR1estrogen receptor 1Uterus-2.340.017
226SPARCL1SPARC-like 1 (hevin)Uterus-2.330.026
227UPK1Auroplakin 1AUterus-2.290.001
228LCE3Dlate cornified envelope 3DUterus-2.290.029
229EEF1Deukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)Uterus-2.290.000
230HOPXHOP homeoboxUterus-2.290.002
231DSC2desmocollin 2Uterus-2.250.032
232GLTPglycolipid transfer proteinUterus-2.240.006
233H19H19, imprinted maternally expressed transcript (non-protein coding)Uterus-2.240.032
234CXCL14chemokine (C-X-C motif) ligand 14Uterus-2.210.045
235KRT2keratin 2Uterus-2.170.000
236IVLinvolucrinUterus-2.160.020
237HS3ST6heparan sulfate (glucosamine) 3-O-sulfotransferase 6Uterus-2.150.000
238SCARA5scavenger receptor class A, member 5 (putative)Uterus-2.110.001
239BBOX1butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1Uterus-2.100.040
240ABI3BPABI family, member 3 (NESH) binding proteinUterus-2.090.000
241CWH43cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)Uterus-2.080.006
242C9orf169chromosome 9 open reading frame 169Uterus-2.050.003
243OLFM4olfactomedin 4Uterus-2.050.008
244ITPR2inositol 1,4,5-trisphosphate receptor, type 2Uterus-2.030.002
245PDGFDplatelet derived growth factor DUterus-2.030.003
246WNT5Awingless-type MMTV integration site family, member 5AUterus-2.020.042
247KRT78keratin 78Uterus-2.010.017
248CFDcomplement factor D (adipsin)Uterus-2.000.007
249SLURP1secreted LY6/PLAUR domain containing 1Uterus-2.000.004
250TGFBR3transforming growth factor, beta receptor IIIUterus-1.990.000
251LOC441178uncharacterized LOC441178Uterus-1.960.004
252DCNdecorinUterus-1.940.002
253RPLP2ribosomal protein, large, P2Uterus-1.920.000
254RPL27Aribosomal protein L27aUterus-1.920.000
255SFTA2surfactant associated 2Uterus-1.910.005
256KLK10kallikrein-related peptidase 10Uterus-1.900.022
257PTGDSprostaglandin D2 synthase 21kDa (brain)Uterus-1.880.005
258FLRT3fibronectin leucine rich transmembrane protein 3Uterus-1.870.037
259GYS2glycogen synthase 2 (liver)Uterus-1.870.000
260ALOX12Barachidonate 12-lipoxygenase, 12R typeUterus-1.860.033
261TGM3transglutaminase 3Uterus-1.860.019
262CRISP2cysteine-rich secretory protein 2Uterus-1.860.011
263ATP6V0E1ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1Uterus-1.840.004
264RP11-680F20.6uncharacterized LOC338667Uterus-1.840.000
265DEGS1delta(4)-desaturase, sphingolipid 1Uterus-1.830.004
266ALOX15Barachidonate 15-lipoxygenase, type BUterus-1.810.005
267SPON1spondin 1, extracellular matrix proteinUterus-1.810.028
268LARP1BLa ribonucleoprotein domain family, member 1BUterus-1.800.012
269TRPS1trichorhinophalangeal syndrome IUterus-1.780.044
270CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 5Uterus-1.760.033
271TMEM184Atransmembrane protein 184AUterus-1.760.009
272BCHEbutyrylcholinesteraseUterus-1.750.001
273LMO4LIM domain only 4Uterus-1.750.011
274RPL14ribosomal protein L14Uterus-1.750.001
275SAMD5sterile alpha motif domain containing 5Uterus-1.730.005
276EMP1epithelial membrane protein 1Uterus-1.730.014
277KRT10keratin 10Uterus-1.710.017
278TXNthioredoxinUterus-1.700.003
279PEG3paternally expressed 3Uterus-1.650.001
280TP53AIP1tumor protein p53 regulated apoptosis inducing protein 1Uterus-1.650.044
281ATG9Bautophagy related 9BUterus-1.640.042
282PRAC1prostate cancer susceptibility candidate 1Uterus-1.640.014
283SULT2B1sulfotransferase family, cytosolic, 2B, member 1Uterus-1.640.033
284ARGLU1arginine and glutamate rich 1Uterus-1.630.017
285ZNF273zinc finger protein 273Uterus-1.630.008
286ZSCAN18zinc finger and SCAN domain containing 18Uterus-1.630.027
287KLF4Kruppel-like factor 4 (gut)Uterus-1.620.021
288CGNL1cingulin-like 1Uterus-1.600.037
289LGALSLlectin, galactoside-binding-likeUterus-1.600.035
290SPATA2Lspermatogenesis associated 2-likeUterus-1.590.004
291ABCA8ATP-binding cassette, sub-family A (ABC1), member 8Uterus-1.580.004
292THSD4thrombospondin, type I, domain containing 4Uterus-1.570.000
293ARandrogen receptorUterus-1.570.001
294BBIP1BBSome interacting protein 1Uterus-1.560.012
295DNASE1L3deoxyribonuclease I-like 3Uterus-1.560.030
296CALM3calmodulin 3 (phosphorylase kinase, delta)Uterus-1.550.017
297ZNF91zinc finger protein 91Uterus-1.550.048
298CALRcalreticulinUterus-1.540.012
299AQP1aquaporin 1 (Colton blood group)Uterus-1.520.030
300COX5Bcytochrome c oxidase subunit VbUterus-1.480.005
301SPNS2spinster homolog 2 (Drosophila)Uterus-1.480.047
302RPS11ribosomal protein S11Uterus-1.460.005
303IGFBP5insulin-like growth factor binding protein 5Uterus-1.460.008
304LOC692247uncharacterized LOC692247Uterus-1.460.002
305ANKRD22ankyrin repeat domain 22Uterus-1.460.037
306KIFC1kinesin family member C1Uterus-1.430.001
307BOCBOC cell adhesion associated, oncogene regulatedUterus-1.430.001
308RPL38ribosomal protein L38Uterus-1.420.003
309ZNF43zinc finger protein 43Uterus-1.420.003
310SPINK2serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)Uterus-1.400.040
311BIVMbasic, immunoglobulin-like variable motif containingUterus-1.380.044
312C2orf40chromosome 2 open reading frame 40Uterus-1.360.017
313FAM107Afamily with sequence similarity 107, member AUterus-1.360.023
314ANKRD19Pankyrin repeat domain 19, pseudogeneUterus-1.330.013
315PLA2G4Dphospholipase A2, group IVD (cytosolic)Uterus-1.330.035
316OPLAH5-oxoprolinase (ATP-hydrolysing)Uterus-1.300.037
317PLA2G4Fphospholipase A2, group IVFUterus-1.300.021
318EFNB3ephrin-B3Uterus-1.300.045

Expression patterns in normal tissues for genes affiliated with Cervical Cancer

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Pathways for genes affiliated with Cervical Cancer

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Pathways related to Cervical Cancer according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2FGFR3, HIF1A, VEGFC
210.1FGFR3, WNT6, HIF1A, VEGFC

Compounds for genes affiliated with Cervical Cancer

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Compounds related to Cervical Cancer according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1glyceraldehyde 3-phosphate4410.2EEF1A1, HIF1A, VEGFC
2paraffin449.8FGFR3, CD82, HIF1A, VEGFC

GO Terms for genes affiliated with Cervical Cancer

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Cellular components related to Cervical Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial outer membraneGO:00574110.2ST20, BRI3BP, LETMD1

Biological processes related to Cervical Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of neuroblast proliferationGO:00205210.3HIF1A, VEGFC
2digestive tract morphogenesisGO:04854610.0FGFR3, HIF1A

Molecular functions related to Cervical Cancer according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055159.2FGFR3, VEGFC, HIF1A, MCM3, POU2F3, EEF1A1

Products for genes affiliated with Cervical Cancer

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  • Antibodies
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Sources for Cervical Cancer

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet