Cervical Carcinoma malady

Wikipedia: Cervical cancer is a malignant neoplasm arising from cells originating in the cervix uteri. One of the...⁴⁴ more...

MalaCards: Cervical Carcinoma, also known as cervix carcinoma, is related to cervicitis and carcinoma. An important gene associated with Cervical Carcinoma is PLIN3 (perilipin 3), and among its related pathways are Molecular Mechanisms of Cancer and Pathways in cancer. The compounds calcium and atp have been mentioned in the context of this disorder. Affiliated tissues include lymph node, lung and thyroid, and related mouse phenotypes are mortality/aging and growth/size.

cervical carcinoma 7 33 32 cervix carcinoma 43

Diseases related to cervical carcinoma by text searches and GeneDecks gene sharing:

(show top 50)    (show all 887)

id	Related Disease	Score	Top Affiliating Genes
1	cervicitis	65.1	ZNF384, PIK3CA, PIK3CG, KL, PDCD1, PDCD1LG2
2	carcinoma	64.3	ZNF384, PIK3CA, PIK3CG, KL, PDCD1, PDCD1LG2
3	adenocarcinoma	44.1	PIK3CA, PIK3CG, RECK, RELA, REV1, CNR1
4	cervical cancer	40.9	PIK3CA, PIK3CG, PDCD1, RECQL4, RELA, VTN
5	breast carcinoma	40.6	PIK3CA, PIK3CG, RECK, KIT, KITLG, VTN
6	thyroiditis	39.7	PIK3CA, PIK3CG, RECK, RELA, KIT, KITLG
7	esophagitis	38.9	PIK3CA, PIK3CG, PDCD1LG2, RECK, RELA, REV1
8	hypoxia	37.3	PIK3CA, PIK3CG, RECK, RELA, WARS, KIT
9	retinoblastoma	36.2	PIK3CA, PIK3CG, RECK, KIT, KITLG, PCNA
10	endometrial carcinoma	36.1	PIK3CA, PIK3CG, RELA, KIT, PCNA, RB1
11	cervical intraepithelial neoplasia	35.8	PIK3CA, PCNA, RB1, RBP1, RBL1, VEGFA
12	papilloma	35.6	PCNA, RB1, RBL1, SERPINB3, VIM, VEGFA
13	nasopharyngitis	33.5	PIK3CA, PIK3CG, PDCD1, RECK, RELA, KIT
14	squamous cell carcinoma	33.0	RBP1, SERPINB3, CD44, CDH1, MKI67, GSTP1
15	ovarian cancer	32.1	RB1, RBL1, CHEK2, CDKN1A, CDK2, CDKN2B
16	intraepithelial neoplasm	32.0	PCNA, BMP6, XRCC1, CDKN2A, MKI67, FAP
17	cervix carcinoma	31.8	MYC, BECN1, CDKN1A, CDKN2A, CDKN3, CD44
18	cervical adenocarcinoma	31.7	PCNA, MYC, RASSF1, PARP1, LAMC2, CFLAR
19	breast cancer	31.0	PIK3CA, RECK, RBP1, MYC, BMP6, LDLR
20	choriocarcinoma	30.8	PIK3CG, PCNA, VDR, MYC, LIF, CGB7
21	herpes simplex	30.4	PIK3CA, PIK3CG, RECK, PCNA, VIM, VEGFA
22	lung carcinoma	25.1	PIK3CA, PIK3CG, RECK, PCNA, RB1, RBL1
23	prostatitis	23.8	PIK3CA, PIK3CG, KL, PDCD1, RECK, RECQL4
24	thrombosis	23.4	PIK3CG, RECK, VTN, PCNA, SETD2, VEGFA
25	leukemia	22.3	ZNF384, PIK3CA, PIK3CG, PDCD1, PDCD1LG2, RECK
26	melanoma	21.6	PIK3CA, PIK3CG, KL, PDCD1, PDCD1LG2, RECK
27	pancreatitis	21.4	PIK3CA, PIK3CG, KL, PDCD1LG2, RECK, RELA
28	hepatocellular carcinoma	20.8	ZNF384, PIK3CA, PIK3CG, KL, PDCD1, PDCD1LG2
29	gastric cancer	20.6	PIK3CA, PIK3CG, RECK, RELA, CNBP, WARS
30	colon cancer	20.0	PIK3CA, PIK3CG, RECK, RELA, CNBP, CNR1
31	ovarian carcinoma	19.4	PIK3CA, PIK3CG, RECK, RELA, REV1, KIT
32	neuronitis	19.2	ZNF384, PIK3CA, PIK3CG, RECK, RELA, CNR1
33	oral squamous cell carcinoma	19.0	PIK3CA, PDCD1, PDCD1LG2, RECK, VTN, PCNA
34	renal cell carcinoma	18.9	PIK3CA, PDCD1, RELA, KIT, PCNA, SETD2
35	boomerang dysplasia	18.7	PIK3CA, PCNA, RB1, MYC, RARB, BCL2
36	bartter disease	18.7	PIK3CA, PCNA, RB1, RBP1, SERPINB3, SETD2
37	non-small cell lung carcinoma	18.5	PCNA, RB1, SETD2, VEGFA, VEGFC, MYC
38	neuroblastoma	18.5	PIK3CA, PIK3CG, RECK, RELA, CNR1, KIT
39	esophageal squamous cell carcinoma	18.2	PIK3CA, RECK, RELA, KIT, PCNA, RB1
40	rectal cloacogenic carcinoma	17.8	RECK, PCNA, RB1, BSG, VEGFC, BIRC5
41	medulloblastoma	17.8	PIK3CA, PIK3CG, KIT, PCNA, RB1, RBL1
42	b-cell lymphomas	17.5	CNR1, RB1, RBL1, MYC, MYCN, BIRC2
43	adenoma	17.4	PIK3CA, RECK, CNR1, KIT, KITLG, PCNA
44	sarcoma	17.3	ZNF384, PIK3CA, PIK3CG, RECK, RELA, WARS
45	gastric adenocarcinoma	17.3	PIK3CA, VEGFC, MYC, BID, BIRC5, BCL2
46	endometrial cancer	17.2	PIK3CA, PIK3CG, KITLG, PCNA, RB1, RBL1
47	small-cell cancer of lung	17.1	PIK3CA, PIK3CG, KIT, KITLG, RB1, RBL1
48	laryngeal squamous cell carcinoma	16.7	RECQL4, PCNA, RB1, RBP1, BSG, VEGFA
49	lung benign neoplasm	16.7	PIK3CG, RB1, RBL1, RARB, RASSF1, KDR
50	burkitt's lymphoma	16.7	MYC, MYCN, MYB, BMP6, RASSF1, BIRC2

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to cervical carcinoma:

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MGI Mouse Phenotypes related to cervical carcinoma:

²⁵ (show all 29)

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	mortality/aging	MP:0010768	19.8	PIK3CA, KL, PDCD1, PDCD1LG2, RECK, RECQL4
2	growth/size phenotype	MP:0005378	19.4	ZNF384, PIK3CA, PIK3CG, KL, RECK, RECQL4
3	homeostasis/metabolism phenotype	MP:0005376	17.5	PIK3CA, PIK3CG, KL, PDCD1LG2, RELA, CNR1
4	hematopoietic system phenotype	MP:0005397	16.9	PDCD1, PDCD1LG2, RECQL4, REV1, KIT, PCNA
5	embryogenesis phenotype	MP:0005380	16.4	PIK3CA, RECK, RECQL4, CNBP, KIT, RBL1
6	immune system phenotype	MP:0005387	16.1	KL, RECQL4, REV1, KIT, RBP1, RBL1
7	cellular phenotype	MP:0005384	16.1	PIK3CA, PIK3CG, KL, PDCD1, PDCD1LG2, RECQL4
8	integument phenotype	MP:0010771	14.3	PIK3CG, KL, RECK, RECQL4, RELA, CNR1
9	nervous system phenotype	MP:0003631	14.2	KL, PDCD1, RECK, RELA, CNBP, CNR1
10	digestive/alimentary phenotype	MP:0005381	14.0	KL, RECQL4, KIT, KITLG, RB1, RBL1
11	renal/urinary system phenotype	MP:0005367	13.8	KL, PDCD1, KIT, MYCN, RARB, BHMT
12	normal phenotype	MP:0002873	13.7	RELA, REV1, VTN, RBL1, VEGFA, MYC
13	skeleton phenotype	MP:0005390	13.3	ZNF384, PIK3CG, RECK, RELA, CNBP, CNR1
14	behavior/neurological phenotype	MP:0005386	13.2	PIK3CA, KL, CNR1, KIT, RB1, RBL1
15	no phenotypic analysis	MP:0003012	12.7	PDCD1LG2, CNR1, PCNA, RB1, RBL1, VEGFA
16	craniofacial phenotype	MP:0005382	12.7	RECQL4, CNBP, KIT, KITLG, RBL1, MYCN
17	endocrine/exocrine gland phenotype	MP:0005379	12.6	ZNF384, KL, RBL1, BCL2L2, LGR4, LDLR
18	limbs/digits/tail phenotype	MP:0005371	12.0	KL, RECK, RECQL4, RELA, KIT, KITLG
19	hearing/vestibular/ear phenotype	MP:0005377	11.7	KIT, KITLG, RB1, RBP1, VDR, MYC
20	cardiovascular system phenotype	MP:0005385	11.6	PIK3CA, PIK3CG, KL, PDCD1, RECK, RELA
21	vision/eye phenotype	MP:0005391	11.5	PIK3CA, PDCD1, RECQL4, RELA, CNBP, KIT
22	reproductive system phenotype	MP:0005389	11.4	ZNF384, PIK3CA, RBP1, RBL1, VEGFA, VDR
23	respiratory system phenotype	MP:0005388	11.4	KL, MYCN, LIF, BID, ASCL1, CCR2
24	pigmentation phenotype	MP:0001186	11.4	RECQL4, KIT, KITLG, RB1, RBP1, MYC
25	muscle phenotype	MP:0005369	11.4	PIK3CA, PIK3CG, KL, PDCD1, RELA, KIT
26	tumorigenesis	MP:0002006	11.3	PIK3CA, PDCD1LG2, RECQL4, KIT, KITLG, RB1
27	other phenotype	MP:0005395	11.1	KL, RECK, CNR1, RARB, KDR, LDLR
28	liver/biliary system phenotype	MP:0005370	10.7	RECK, KIT, RBP1, RBL1, VEGFA, MYCN
29	adipose tissue phenotype	MP:0005375	9.1	PIK3CA, KL, CNR1, RB1, RBL1, MYC

Articles related to cervical carcinoma:

(show top 50)    (show all 511)

id	Title	Authors	Year	Affiliating Genes
1	Stabilization of mismatch repair gene PMS2 by glycoge n synthase kinase 3beta is implicated in the treatment of cervical carcinoma. (20178594)	Zhang Y.... Li H.B.	2010	GSK3B, PMS2
2	The LIG4 Ile658Val polymorphism does not affect the r isk of cervical carcinoma. (20400235)	Ding Z.... Chen H.	2010	LIG4
3	A phase II study of sunitinib in patients with locall y advanced or metastatic cervical carcinoma: NCIC CTG Trial IND.184. (19740535)	Mackay H.J.... Eisenhauer E.A.	2010	KIT, VEGFA, KITLG
4	Identification of an active site of EMMPRIN for the a ugmentation of matrix metalloproteinase-1 and -3 expression in a co-culture of human uterine cervical carcinoma cells and fibroblasts. (19427027)	Sato T.... Ito A.	2009	BSG
5	MVP expression is related to IGF1-R in cervical carcinoma patients treated by radiochemotherapy. (18599112)	Lloret M.... Ruiz A.	2008	IGF1R, MVP
6	The tyrphostin B42 inhibits cell proliferation and HER-2 autophosphorylation in cervical carcinoma cell lines. (18259943)	Soto-Cruz I.... CA!ceres-CortAcs J.R.	2008	ERBB2
7	Overexpressed active Notch1 induces cell growth arrest of HeLa cervical carcinoma cells. (17425682)	Wang L.... Han H.	2007	NOTCH1
8	The possible role of cell cycle regulators in multistep process of HPV-associated cervical carcinoma. (17521451)	Bahnassy A.A.... Shawki O.	2007	CDK4, MDM2, RB1
9	Expression of HuR is associated with increased cyclooxygenase-2 expression in uterine cervical carcinoma. (17581403)	Lim S.J.... Lee C.M.	2007	PTGS2, ELAVL1
10	Human papillomavirus E7 repression in cervical carcinoma cells initiates a transcriptional cascade driven by the retinoblastoma family, resulting in senescence. (17182682)	Johung K.... DiMaio D.	2007	RB1
11	Relationship between cyclin G1 and human papilloma virus infection in cervical intraepithelial neoplasia and cervical carcinoma. (16845792)	Liang J.... Liu J.	2006	CCNG1
12	Specific HIV protease inhibitors inhibit the ability of HPV16 E6 to degrade p53 and selectively kill E6-dependent cervical carcinoma cells in vitro. (17310826)	Hampson L.... Hampson I.N.	2006	TP53
13	Glucocorticoids enhance cytotoxicity of cisplatin via suppression of NF-{kappa}B activation in the glucocorticoid receptor-rich human cervical carcinoma cell line SiHa. (16461557)	Lu Y.S.... Cheng A.L.	2006	NR3C1
14	Influence of prostaglandin A2 and 2-methoxyestradiol on Bax and Bcl-2 expression levels in cervical carcinoma cells. (15889622)	Joubert A.... Joubert F.	2005	BCL2, BAX
15	Protective role of the polymorphism CCR2-64I in the progression from squamous intraepithelial lesions to invasive cervical carcinoma. (15721423)	Coelho A.... Medeiros R.	2005	CCR2
16	Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis. (15611226)	Hill S.C.... Eliopoulos A.G.	2005	CD40
17	Transcriptional regulation of beta-defensin-2 by lipopolysaccharide in cultured human cervical carcinoma (HeLa) cells. (15985221)	Mineshiba J.... Takashiba S.	2005	DEFB4A
18	CD44v6 as a prognostic factor in cervical carcinoma FIGO stage IB. (15816636)	Bouda J.... Speiser P.	2005	CD44
19	Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion. (16061633)	Zhai Y.... Cho K.R.	2005	MMP14
20	Ge-Jee-Bok-Ryung-Hwan induces apoptosis in human cervical carcinoma HeLa cells--an endoplasmic reticulum stress pathway--. (15474552)	Chae H.J.... Kim H.R.	2004	HSPA5, CYCS, BCL2L15
21	The c-myc activation in cervical carcinomas and HPV 16 infections. (14729369)	Abba M.C.... Golijow C.D.	2004	MYC
22	Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells. (15047823)	Horner S.M.... DiMaio D.	2004	TP53
23	Homeobox gene expression and mutation in cervical carcinoma cells. (12824890)	Hung Y.C.... Ueki M.	2003	HOXA1, HOXA13, LBX1
24	Clinical significance of interleukin-1 receptor antagonist in patients with cervical carcinoma. (12694657)	Fujiwaki R.... Miyazaki K.	2003	IL1RN
25	Inactivation of RAS association domain family 1A gene in cervical carcinomas and the role of human papillomavirus infection. (12702579)	Kuzmin I.... Pfeifer G.P.	2003	RASSF1
26	Alterations in promoter usage and expression levels of insulin-like growth factor-II and H19 genes in cervical carcinoma exhibiting biallelic expression of IGF-II. (11997082)	Kim S.J.... Oh Y.K.	2002	IGF2, H19
27	Correlation between thymidine phosphorylase expression and invasion phenotype in cervical carcinoma cells. (11275979)	Ueda M.... Ueki M.	2001	TYMP
28	Higher incidence of p53 mutation in cervical carcinomas with intermediate-risk HPV infection. (11574134)	Kim H.J.... Hwang T.S.	2001	TP53
29	Histopathologic subtyping of cervical adenocarcinoma reveals increasing incidence rates of endometrioid tumors in all age groups: a population based study with review of all nonsquamous cervical carcinomas in Norway from 1966 to 1970, 1976 to 1980, and 1986 to 1990. (11002225)	Alfsen G.C.... Abeler V.M.	2000	NOS2
30	Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma cells. (10675384)	Wu R.... Cho K.R.	2000	FHIT
31	Thymidine phosphorylase expression in tumor stroma of uterine cervical carcinomas: histological features and microvessel density. (10695991)	Tang W.... Kakudo K.	2000	TYMP
32	Expression of cyclin E and p27(KIP1) in cervical carcinoma. (10779628)	Tae Kim Y.... Ho Lee S.	2000	CDKN1B
33	Clinicopathological implication of cripto expression in early stage invasive cervical carcinomas. (10885604)	Ertoy D.... Ayhan A.	2000	TDGF1
34	Transient increases of apoptosis and Bax expression occurring during radiotherapy in patients with invasive cervical carcinoma. (10391567)	Kokawa K.... Nakano R.	1999	BAX
35	Immunohistochemical analysis of 1,25-dihydroxyvitamin D3 receptor in cervical carcinoma. (9792274)	Reichrath J.... Friedrich M.	1998	VDR
36	Metabolism and ribonucleotide reductase inhibition of (E)-2'-deoxy-2'-(fluoromethylene)cytidine, MDL 101,731, in human cervical carcinoma HeLa S3 cells. (9488595)	Takahashi T.... Okabe M.	1998	DCK
37	APM-1, a novel human gene, identified by aberrant co-transcription with papillomavirus oncogenes in a cervical carcinoma cell line, encodes a BTB/POZ-zinc finger protein with growth inhibitory activity. (9427755)	Reuter S.... Schwarz E.	1998	ZBTB7C
38	Enhanced radiosensitization with interferon-alpha-2b and cisplatin in the treatment of locally advanced cervical carcinoma. (9441780)	Stock R.G.... Cohen C.	1997	IFNA2, IFNA1
39	Stimulatory effects of EGF and TGF-alpha on invasive activity and 5'-deoxy-5-fluorouridine sensitivity in uterine cervical-carcinoma SKG-IIIb cells. (9378537)	Ueda M.... Yanagihara T.	1997	EGF, TGFA
40	High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas. Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19. (8570220)	Douc-Rasy S.... Riou G.	1996	IGF2, H19
41	The induction of apoptosis in human cervical carcinoma (HeLa) cells by gamma-linolenic acid. (9014218)	De Kock M.... Seegers J.C.	1996	PCNA
42	BCL-2 immunoreactivity increases with severity of CIN: a study of normal cervical epithelia, CIN, and cervical carcinoma. (8691340)	ter Harmsel B.... Ramaekers F.	1996	BCL2
43	Bcl-2 protooncogene expression in cervical carcinoma cell lines containing inactive p53. (7768985)	Liang X.H.... Herman B.	1995	BCL2
44	The relationship between proliferating cell nuclear antigen (PCNA), nuclear DNA content and mutant p53 during genesis of cervical carcinoma. (7718254)	Steinbeck R.G.... Auer G.U.	1995	TP53, PCNA
45	Cytotoxic action of cis-unsaturated fatty acids on human cervical carcinoma (HeLa) cells in vitro. (8577783)	Sagar P.S.... Das U.N.	1995	SOD1, CAT
46	MHC class I expression in HPV 16 positive cervical carcinomas is post-transcriptionally controlled and independent from c-myc overexpression. (8414499)	Cromme F.V.... Walboomers J.M.	1993	MYC
47	Correlation between HPV positivity and state of the p53 gene in cervical carcinoma cell lines. (8380785)	Iwasaka T.... Sugimori H.	1993	TP53
48	Cathepsin-D expression in cervical carcinoma and its prognostic significance. (8322451)	Mitchell K.M.... Smith D.	1993	CTSD
49	Repression of endogenous p53 transactivation function in HeLa cervical carcinoma cells by human papillomavirus type 16 E6, human mdm-2, and mutant p53. (8388491)	Hoppe-Seyler F.... Butz K.	1993	MDM2, TP53
50	The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. (1648218)	Scheffner M.... Howley P.M.	1991	TP53, RB1

Genes related to cervical carcinoma according to GeneCards:

(show top 50)    (show all 443)

id	Symbol	Description	Score	GeneCards Section Context
1	PLIN3	perilipin 3	11.0	Publications
2	POU4F1	POU class 4 homeobox 1	11.0
3	IRF9	interferon regulatory factor 9	11.0	Publications
4	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	11.0	Publications
5	SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3	11.0	Publications
6	TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	11.0	Publications
7	BAG1	BCL2-associated athanogene	11.0	Publications
8	CGB7	chorionic gonadotropin, beta polypeptide 7	11.0	Publications
9	HOXA1	homeobox A1	11.0	Publications
10	H19	H19, imprinted maternally expressed transcript (non-protein coding)	11.0	Publications
11	CCL7	chemokine (C-C motif) ligand 7	11.0	Publications
12	MMP15	matrix metallopeptidase 15 (membrane-inserted)	11.0	Publications
13	SPINK1	serine peptidase inhibitor, Kazal type 1	11.0	Publications
14	CA9	carbonic anhydrase IX	11.0	Publications
15	RBP1	retinol binding protein 1, cellular	11.0	Publications
16	CDC25A	cell division cycle 25 homolog A (S. pombe)	11.0	Publications
17	IFI27	interferon, alpha-inducible protein 27	11.0	Publications
18	HSD3BP4	hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 4	11.0
19	IRF1	interferon regulatory factor 1	11.0	Publications
20	CD82	CD82 molecule	11.0	Publications
21	KRT10	keratin 10	11.0	Publications
22	NME2	NME/NM23 nucleoside diphosphate kinase 2	11.0	Publications
23	KRT1	keratin 1	11.0	Publications
24	FOSL1	FOS-like antigen 1	11.0
25	UBE3A	ubiquitin protein ligase E3A	11.0	Publications
26	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	11.0
27	TYMP	thymidine phosphorylase	11.0	Publications
28	ST14	suppression of tumorigenicity 14 (colon carcinoma)	11.0	Publications
29	DFFB	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	11.0
30	PAEP	progestagen-associated endometrial protein	11.0
31	TGM1	transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)	11.0
32	EDNRA	endothelin receptor type A	11.0	Publications
33	ENO1	enolase 1, (alpha)	11.0
34	TERC	telomerase RNA component	11.0
35	TFF1	trefoil factor 1	11.0
36	TIMP3	TIMP metallopeptidase inhibitor 3	11.0	Publications
37	CD59	CD59 molecule, complement regulatory protein	11.0	Publications
38	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	11.0	Publications
39	TP53	tumor protein p53	11.0	Publications
40	CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1	11.0	Publications
41	DEFB4A	defensin, beta 4A	11.0	Publications
42	DNASE1	deoxyribonuclease I	11.0	Publications
43	ENOX2	ecto-NOX disulfide-thiol exchanger 2	11.0
44	JUP	junction plakoglobin	11.0	Publications
45	RASSF1	Ras association (RalGDS/AF-6) domain family member 1	11.0	Publications
46	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	11.0
47	KRT8	keratin 8	11.0	Publications
48	MMP14	matrix metallopeptidase 14 (membrane-inserted)	11.0	Publications
49	MVP	major vault protein	11.0	Publications
50	MYB	v-myb myeloblastosis viral oncogene homolog (avian)	11.0	Publications

Pathways related to cervical carcinoma according to GeneDecks:

(show top 50)    (show all 239)

id	Pathway	Score	Top Affiliating Genes
1	Molecular Mechanisms of Cancer36	12.8	PIK3CG, KITLG, RB1, RBL1, VEGFC, MYC
2	Pathways in cancer20	12.4	PIK3CA, PIK3CG, RELA, RB1, VEGFA, VEGFB
3	Bladder cancer20	12.0	RB1, VEGFA, VEGFB, VEGFC, MYC, RASSF1
4	Immune System38	12.0	PDCD1, PDCD1LG2, CD274, CD40, CDH1, IRF1
5	P2Y Receptor Signaling36	11.9	KIT, VEGFB, VEGFC, MYC, KDR, JUN
6	Focal adhesion20	11.8	PIK3CA, PIK3CG, VTN, VEGFB, VEGFC, BIRC2
7	ErbB signaling pathway20	11.7	PIK3CA, PIK3CG, MYC, JUN, CDKN1A, CDKN1B
8	Transcription_P53 signaling pathway41	11.5	RELA, RB1, VEGFA, KDR, BCL2, ATM
9	Signal transduction PTEN pathway10	11.4	PIK3CA, PCNA, JUN, CDKN1A, GSK3B, MAPK1
10	Prostate cancer20	11.4	PIK3CA, PIK3CG, RELA, RB1, BCL2, CDKN1A
11	Endometrial cancer20	11.4	PIK3CA, PIK3CG, MYC, AXIN1, CDH1, MAPK1
12	Melanoma20	11.4	PIK3CA, PIK3CG, RB1, CDKN1A, CDKN2A, CDK4
13	p53 Signaling36	11.4	BCL2, CHEK1, CHEK2, BAX, ATM, CDKN1A
14	Glioblastoma Multiforme36	11.3	RB1, AXIN1, CDKN1A, CDK2, CDKN1B, CDK4
15	Apoptosis and survival TNFR1 signaling pathway10	11.2	RELA, BID, BIRC2, BAX, XIAP, CFLAR
16	Cell cycle_Regulation of G1/S transition (part 2)41	11.2	RELA, RB1, RBL1, JUN, CDK2, CDK4
17	Cell cycle20	11.2	PCNA, RB1, RBL1, MYC, CHEK1, CHEK2
18	14-3-3 Induced Intracellular Signaling36	11.1	KITLG, VEGFB, VEGFC, JUN, FLT4, AREG
19	Transcription P53 signaling pathway10	11.1	RELA, VEGFA, CDK2, CDKN2A, APEX1, MAPK8
20	Immune response MIF-JAB1 signaling10	11.1	RELA, UCHL1, JUN, CDK2, CDKN1B, CDK4
21	Apoptosis20	10.9	PIK3CA, PIK3CG, RELA, BID, BIRC2, BCL2
22	Chronic myeloid leukemia20	10.9	PIK3CA, PIK3CG, RELA, RB1, MYC, CDKN1A
23	Glioma Invasiveness36	10.9	KITLG, VTN, VEGFB, VEGFC, BMP6, CD44
24	DNA damage ATM/ATR regulation of G1/S checkpoint10	10.9	MYC, CHEK1, CHEK2, ATM, CDK2, CDK4
25	Signal transduction AKT signaling10	10.8	GSK3B
26	Cyclins and Cell Cycle Regulation36	10.8	RB1, ATM, CDKN1A, CDK2, CDKN2B, CDKN1B
27	Angiogenesis3	10.8	RECK, VEGFB, VEGFC, KDR, JAG1, MMP2
28	Estrogen-mediated S-Phase Entry36	10.7	RB1, RBL1, MYC, CDK2, CDKN1B, CDK4
29	Telomerase Components in Cell Signaling36	10.6	KIT, KITLG, RB1, VEGFB, VEGFC, MYC
30	G1-S Phase Transition36	10.4	RB1, ATM, CDKN1A, CDK2, CDKN2B, CDKN1B
31	NFAT in Immune Response36	10.2	KIT, KITLG, VEGFB, VEGFC, BMP6, KDR
32	Colorectal cancer20	10.1	PIK3CG, AXIN1, MSH2, GSK3B, MAPK8, CASP9
33	eNOS Signaling36	10.0	KIT, KITLG, BMP6, FLT4, AREG, FIGF
34	mTOR Pathway36	10.0	KITLG, VEGFB, VEGFC, BMP6, AREG, FIGF
35	eIF2 Pathway36	9.9	KIT, KITLG, VEGFC, BMP6, FLT4, AREG
36	Estrogen Pathway36	9.7	KIT, KITLG, VEGFB, VEGFC, BMP6, KDR
37	Jak-STAT signaling pathway20	9.7	PIK3CA, PIK3CG, MYC, IRF9, IL10, IL15
38	Rac1 Pathway36	9.7	KITLG, VEGFB, BMP6, KDR, JUN, FLT4
39	Osteoclast differentiation20	9.6	PIK3CA, PIK3CG, RELA, JUN, FOSL1, IRF9
40	Endothelin-1 Signaling Pathway36	9.5	KIT, MYC, BMP6, CD80, FLT4, FGFR3
41	p53 Mediated Apoptosis36	9.3	KIT, KITLG, VEGFB, VEGFC, BMP6, BID
42	p38 Signaling36	8.8	KIT, KITLG, VEGFB, VEGFC, BMP6, LIF
43	TGF-Beta Pathway36	8.6	KITLG, VEGFB, VEGFC, BMP6, KDR, BCL2
44	Tec Kinases Signaling36	8.5	KITLG, VEGFB, VEGFC, BMP6, BCL2, BAX
45	p70S6K Signaling36	8.5	KIT, KITLG, VEGFB, VEGFC, BMP6, KDR
46	ERK Signaling36	8.5	KIT, KITLG, VEGFB, VEGFC, MYC, BMP6
47	NF-KappaB (p50-p65) Pathway36	8.5	RELA, KITLG, VEGFB, VEGFC, BMP6, KDR
48	NF-KappaB Family Pathway36	8.4	RELA, KITLG, VEGFB, VEGFC, BMP6, KDR
49	MIF Regulation of Innate Immune Cells36	8.3	BMP6, LIF, BCL2, BAX, JUN, CD80
50	MIF Mediated Glucocorticoid Regulation36	8.2	BMP6, LIF, BCL2, BAX, CD80, IL10

Compounds related to cervical carcinoma according to GeneDecks:

(show top 50)    (show all 487)

id	Compound	Score	Top Affiliating Genes
1	calcium32 9 18 9	22.3	KL, RECK, RELA, CNR1, KIT, KITLG
2	atp32	16.2	PIK3CA, RECK, CNBP, WARS, WARS2, KIT
3	cysteine32	15.1	RECK, VTN, PCNA, VDAC1, VDR, MYB
4	12-o-tetradecanoylphorbol 13-acetate32	14.2	RB1, MYC, BMP6, RARB, LIF, UCHL1
5	cholesterol32 9 18 9	16.7	PIK3CA, RECK, CNBP, KITLG, VTN, RB1
6	nitric oxide32 9 18 9	16.5	KIT, KITLG, RB1, VEGFC, VDAC1, MYCN
7	cyclic amp32 18	14.1	CNR1, RB1, SETD2, RARB, LIF, BID
8	hydrogen32 18	13.9	RBP1, CHGA, MTR, CDK4, CDK1, CD40
9	sucrose32 9 18 9	15.8	RECK, BSG, VDAC1, CHGA, MVP, JUP
10	resveratrol32 9 18 9	15.7	PIK3CA, PIK3CG, PCNA, RB1, BSG, VEGFA
11	agarose32	12.7	CNBP, KIT, KITLG, MYC, MYCN, LIF
12	bromodeoxyuridine32	12.4	PIK3CA, KITLG, PCNA, RB1, VIM, MYC
13	paclitaxel32 34 9 9	15.3	PIK3CA, PIK3CG, KIT, KITLG, PCNA, RB1
14	lactacystin32	12.3	PIK3CG, RBL1, VDR, MYC, MYCN, BIRC5
15	tamoxifen32 34 9 9	15.2	PIK3CA, VTN, PCNA, VIM, VEGFA, VDR
16	phosphotyrosine32	12.2	PIK3CA, PIK3CG, RECK, KIT, KDR, JUP
17	chloramphenicol32 9 9	14.1	SETD2, VIM, VDR, MYC, MYCN, MYB
18	rotenone32	11.9	PIK3CG, PARP1, BCL2, GSR, IL1A, MAPK8
19	egcg32	11.8	PIK3CG, LDLR, XIAP, CDK2, IVL, IL1A
20	sulindac32 9 9	13.7	PCNA, BIRC5, BCL2, BAX, XIAP, CDKN1A
21	olomoucine32 42 9 9	14.7	PCNA, RB1, BCL2, BAX, CDKN1A, CDK2
22	gold32	11.6	RECK, KIT, KITLG, VDAC1, CHGA, LAMC2
23	histidine32	11.6	KITLG, CHEK1, CHGA, MTR, XRCC1, CDKN2A
24	sp 60012532 42	12.5	PIK3CG, BID, BIRC2, CDKN1A, CD40, MMP1
25	guanine32 9 18 9	14.5	CNR1, SETD2, VDR, MYB, BIRC5, CHGA
26	cytosine32 18	12.4	MYB, RASSF1, CDH1, MBD1, IFNB1, TYMP
27	ionomycin32	11.4	SETD2, CD274, CDK4, CD40, GRP, GNRHR
28	trastuzumab32 34 9 9	14.4	PIK3CA, PIK3CG, KIT, VEGFC, BIRC5, KDR
29	hematoxylin32	11.3	KIT, PCNA, VIM, CHGA, CEACAM5, CDKN2A
30	imatinib32 34 9 9	14.3	PIK3CA, PIK3CG, KIT, KITLG, VEGFA, MYC
31	staurosporin32	11.1	PIK3CA, PIK3CG, BCL2, JUN, CDKN3, MAPK10
32	methylmethanesulfonate32	11.1	PCNA, PARP1, CHEK1, XRCC1, XRCC6, JUN
33	vitamin-e32	11.0	BIRC2, BIRC5, XIAP, B2M, CFLAR, CD40
34	pd15303532	11.0	PIK3CG, VEGFA, BIRC5, JUN, MMP1, AREG
35	daunorubicin32 9 9	13.0	RELA, KITLG, MYC, BIRC5, BCL2, MVP
36	bryostatin 132	10.9	MYC, BIRC2, BIRC5, BCL2, XIAP, CDKN1A
37	1,25 dihydroxy vitamin d332	10.9	RB1, VDR, MYC, BMP6, LIF, CHEK1
38	batimastat32 42 9 9	13.8	CD36, MMP1, MMP13, MMP14, MMP15, MMP16
39	folate32	10.7	RECK, VIM, VDR, MYC, RASSF1, BHMT
40	sodium dodecylsulfate32	10.6	VTN, VDAC1, MYC, BMP6, CDH1, IVL
41	carbon32	10.6	CNR1, VTN, PCNA, VDR, LDLR, MTHFR
42	leucovorin32 34 9 9	13.5	VEGFA, CEACAM5, IL15, IGF2, IFNA1, IFNA2
43	bicalutamide32 42 9 9	13.1	PIK3CG, VDR, CHGA, CDK2, CDKN3, FGF7
44	ibmx32	10.0	RARB, CDK2, CDKN3, MME, MMP2, FGF2
45	formaldehyde32 18	10.8	KIT, PCNA, RB1, VIM, CHGA, B2M
46	troglitazone32 42 9 9	12.6	PIK3CG, RB1, VDR, BMP6, BIRC5, BCL2
47	cytochalasin d32 42	10.5	PIK3CG, KITLG, VTN, VIM, LDLR, CD36
48	vitamin d32	9.4	VIM, VDR, BMP6, RARB, CHGA, LDLR
49	pdtc32	9.2	PIK3CA, PIK3CG, SETD2, BIRC5, PARP1, BCL2
50	chloroquine32 34 9 9	11.6	KIT, VTN, BMP6, LDLR, B2M, CD4

Cellular components related to cervical carcinoma according to GeneDecks:

(show all 11)

id	Name	GO ID	Score	Top Affiliating Genes
1	nucleus	GO:005634	16.9	NFKB1, SMAD1, NR3C1, PPARG, CTNNB1, SP1
2	cytoplasm	GO:005737	16.3	RELA, RECQL4, PIK3CG, STAT1, HES1, G6PD
3	cytosol	GO:005829	16.0	SOD1, PRKAB1, PRKCD, PSMC4, PSMB8, PSMD9
4	plasma membrane	GO:005886	13.9	PTGER2, PTEN, TNF, HLA-G, HLA-C, HLA-A
5	nucleoplasm	GO:005654	13.8	MGMT, JUN, ATM, XRCC6, XRCC5, XRCC1
6	integral to plasma membrane	GO:005887	12.4	PTGER2, TNFSF12, TNF, TPBG, HLA-C, HLA-A
7	membrane	GO:016020	11.0	LTA, KRT1, NR3C1, CTNNB1, CYP19A1, PTGES
8	transcription factor complex	GO:005667	11.0	SMAD1, SMAD2, SMAD3, SMAD4, HIF1A, TWIST2
9	external side of plasma membrane	GO:009897	9.6	CXCL12, IL2RB, IL17A, FCGR3A, FGA, CD9
10	extracellular region	GO:005576	9.4	IL1A, MMP2, MMP13, MMP1, CD55, CD40
11	extracellular space	GO:005615	7.1	PLAU, IFNA2, IGF2, GPI, CCL7, ENOX2

Biological processes related to cervical carcinoma according to GeneDecks:

(show top 50)    (show all 70)

id	Name	GO ID	Score	Top Affiliating Genes
1	small molecule metabolic process	GO:044281	13.3	PIK3CA, PIK3CG, BSG, BHMT, LDLR, MTHFR
2	mitotic cell cycle	GO:000278	13.2	PCNA, RB1, RBL1, MYBL2, BIRC5, AURKA
3	apoptotic process	GO:006915	13.1	PDCD1, VIM, VDAC1, BOK, BLCAP, BID
4	G1/S transition of mitotic cell cycle	GO:000082	12.7	PCNA, RB1, BCL2, CDKN1A, CDK2, CDKN1B
5	angiogenesis	GO:001525	12.4	PIK3CA, PIK3CG, WARS, SETD2, VEGFA, VEGFC
6	induction of apoptosis by intracellular signals	GO:008629	12.2	MYC, BID, BCL2, BAK1, BAX, XIAP
7	heart development	GO:007507	12.1	PCNA, ATM, ID1, CASP3, CASP8, GJA1
8	virus-host interaction	GO:019048	11.8	RELA, RB1, RBL1, VIM, VDAC1, BECN1
9	cell proliferation	GO:008283	11.6	KITLG, PCNA, BOK, LIG4, UCHL1, BAK1
10	cell cycle checkpoint	GO:000075	11.6	RB1, CHEK1, CHEK2, ATM, CDKN1A, CDK2
11	neuron apoptotic process	GO:051402	11.6	RB1, LIG4, BID, BCL2, BAX, ATM
12	activation of pro-apoptotic gene products	GO:008633	11.5	MYC, BID, BCL2, BAK1, BAX, GZMB
13	release of cytochrome c from mitochondria	GO:001836	11.5	MYC, BID, BCL2, BAK1, BAX, JUN
14	DNA repair	GO:006281	11.3	RECQL4, REV1, PCNA, LIG4, PARP1, CHEK1
15	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO:006919	11.1	BOK, MYC, BAX, CDKN1B, CDKN2A, APAF1
16	negative regulation of transcription, DNA-dependent	GO:045892	11.1	RELA, RB1, NACC1, VDR, MYB, BIRC5
17	negative regulation of apoptotic process	GO:043066	11.1	PIK3CG, RELA, VEGFA, MYC, BIRC2, KDR
18	induction of apoptosis	GO:006917	11.0	NACC1, BOK, BAX, CDKN1B, CDKN2A, IRF1
19	response to lipopolysaccharide	GO:032496	11.0	CNR1, S100A9, JUN, MMP9, IL1A, FAS
20	cell cycle arrest	GO:007050	11.0	RB1, MYC, RASSF1, MSH2, ATM, CDKN1A
21	cell surface receptor signaling pathway	GO:007166	11.0	BSG, BIRC2, BAG1, CD36, CD59, CD4
22	negative regulation of transcription from RNA polymerase II promoter	GO:000122	10.9	VDR, MYC, MYB, RARB, PARP1, YBX1
23	signal transduction	GO:007165	10.9	PDCD1, KIT, KITLG, VEGFC, VDR, RARB
24	negative regulation of cell proliferation	GO:008285	10.9	WARS, VDR, RARB, LIF, BECN1, BAK1
25	protein autophosphorylation	GO:046777	10.8	KIT, KDR, CHEK2, AURKA, ATM, FLT4
26	positive regulation of apoptotic process	GO:043065	10.7	CNR1, RARB, BID, BAK1, BAX, ATM
27	response to organic cyclic compound	GO:014070	10.7	BAK1, MSH2, JUN, CDKN1A, CDK1, FOSL1
28	transforming growth factor beta receptor signaling pathway	GO:007179	10.6	RBL1, MYC, ZFYVE9, PARP1, UCHL5, JUN
29	ovarian follicle development	GO:001541	10.6	KIT, KITLG, KDR, BCL2, UBE3A, BAX
30	positive regulation of peptidyl-tyrosine phosphorylation	GO:050731	10.6	KITLG, VTN, VEGFA, VEGFB, LIF, CD36
31	epidermal growth factor receptor signaling pathway	GO:007173	10.6	PIK3CA, CDKN1B, CDK1, GSK3B, MDM2, MAPK1
32	response to ethanol	GO:045471	10.6	CNR1, BCL2, BAK1, S100A9, CDK1, MMP9
33	positive regulation of cell proliferation	GO:008284	10.5	CNBP, KIT, NACC1, VEGFA, VEGFC, MYC
34	positive regulation of cell migration	GO:030335	10.5	VEGFA, KDR, MMP14, CCL7, IGF1R, ETS1
35	negative regulation of cell growth	GO:030308	10.5	RB1, BCL2, CDKN1A, CDKN1B, CDKN2A, INHBA
36	replicative senescence	GO:090399	10.4	CHEK1, CHEK2, ATM, CDKN1A, CDKN2A, MME
37	blood coagulation	GO:007596	10.3	PIK3CA, PIK3CG, BSG, VEGFA, VEGFB, VEGFC
38	cytokine-mediated signaling pathway	GO:019221	10.2	RELA, KIT, B2M, CD44, IRF1, IRF9
39	response to organic nitrogen	GO:010243	10.2	CDKN1A, IL1A, IL1B, IL1RN, CCNE1, CCND1
40	positive regulation of transcription, DNA-dependent	GO:045893	9.9	RELA, CNBP, RB1, MYC, MYB, LGR4
41	positive regulation of protein phosphorylation	GO:001934	9.8	VEGFA, AXIN1, CD40, FLT4, IL1B, CCND3
42	anti-apoptosis	GO:006916	9.6	PIK3CA, RELA, VEGFB, BIRC2, BIRC5, BECN1
43	aging	GO:007568	9.6	KL, CNR1, VDR, BAK1, JUN, IL15
44	positive regulation of MAP kinase activity	GO:043406	9.6	PIK3CG, KITLG, VEGFA, CD40, ERBB2, TNF
45	positive regulation of transcription from RNA polymerase II promoter	GO:045944	9.6	RELA, CNBP, RB1, RBL1, VEGFA, VDR
46	platelet activation	GO:030168	9.5	PIK3CA, PIK3CG, VEGFA, VEGFB, VEGFC, CD36
47	response to hypoxia	GO:001666	9.5	VEGFA, BCL2, XRCC1, ATM, MMP9, FIGF
48	positive regulation of cell division	GO:051781	9.5	VEGFA, VEGFB, VEGFC, YBX1, FIGF, FGF2
49	response to drug	GO:042493	9.2	VEGFC, MYC, BCL2, MVP, BAG1, BAK1
50	response to estradiol stimulus	GO:032355	8.8	VDR, BID, AURKA, MMP15, MMP9, IL1B

Molecular functions related to cervical carcinoma according to GeneDecks:

(show all 13)

id	Name	GO ID	Score	Top Affiliating Genes
1	protein binding	GO:005515	19.6	PGR, GAPDH, GADD45A, PECAM1, PES1, EFEMP1
2	sequence-specific DNA binding transcription factor activity	GO:003700	13.1	CNBP, RB1, VDR, MYC, MYCN, MYBL2
3	ATP binding	GO:005524	12.7	RNASEL, EGFR, ABCB1, EIF2AK3, HK2, TYK2
4	protein homodimerization activity	GO:042803	12.1	TERT, DPYD, TAP1, STAT1, DCK, SOD1
5	transcription factor binding	GO:008134	11.5	SMAD2, SMAD3, HES1, HES5, HIF1A, DNMT1
6	identical protein binding	GO:042802	11.4	TP73, TP63, TP53, ERBB2, ESR1, AKT1
7	protein kinase binding	GO:019901	11.3	SMAD3, SMAD1, PTK2, PTEN, TP73, TP53
8	double-stranded DNA binding	GO:003690	11.2	CTNNB1, NR3C1, SMAD2, SMAD3, NFKB1, EGFR
9	ubiquitin protein ligase binding	GO:031625	10.9	HSPA5, CALR, TP53, SMAD2, SMAD3, HIF1A
10	transcription regulatory region DNA binding	GO:044212	10.5	TNF, SP1, CTNNB1, PPARG, SMAD3, SMAD4
11	enzyme binding	GO:019899	9.5	CTNNB1, PPARG, NOTCH1, EGFR, HIF1A, TGFB1
12	growth factor activity	GO:008083	7.6	KITLG, VEGFA, VEGFB, VEGFC, BMP6, IGF2
13	cytokine activity	GO:005125	7.5	IL4, IL6, GPI, IFNA2, IFNB1, IFNG