MCID: CRV036
MIFTS: 26

Cervical Carcinosarcoma malady

Cancer diseases category

Aliases & Classifications for Cervical Carcinosarcoma

About this section

Cervical Carcinosarcoma, Aliases & Descriptions:

Name: Cervical Carcinosarcoma 9 60
Cervical Malignant Mixed Mesodermal Mullerian Tumor 9
 
Cervical Mixed Epithelial and Mesenchymal Neoplasm 9
Cervical Malignant Mixed Mullerian Tumor 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology9 DOID:4112
NCIt38 C36097

Summaries for Cervical Carcinosarcoma

About this section


MalaCards based summary: Cervical Carcinosarcoma, also known as cervical malignant mixed mesodermal mullerian tumor, is related to cervicitis and cervical wilms' tumor. An important gene associated with Cervical Carcinosarcoma is BIRC5 (baculoviral IAP repeat containing 5), and among its related pathways are Apoptosis and Autophagy and TNF Signaling. The compounds ponicidin and naphtho(1,2-b)furan-4,5-dione have been mentioned in the context of this disorder.

Related Diseases for Cervical Carcinosarcoma

About this section

Graphical network of the top 20 diseases related to Cervical Carcinosarcoma:



Diseases related to cervical carcinosarcoma

Symptoms for Cervical Carcinosarcoma

About this section

Drugs & Therapeutics for Cervical Carcinosarcoma

About this section

Drug clinical trials:

Search ClinicalTrials for Cervical Carcinosarcoma

Search NIH Clinical Center for Cervical Carcinosarcoma

Genetic Tests for Cervical Carcinosarcoma

About this section

Anatomical Context for Cervical Carcinosarcoma

About this section

Animal Models for Cervical Carcinosarcoma or affiliated genes

About this section

Publications for Cervical Carcinosarcoma

About this section

Articles related to Cervical Carcinosarcoma:

idTitleAuthorsYear
1
Coexistence of homologous-type cervical carcinosarcoma with endometrioid-type G1 endometrial cancer: a case report with an immunohistochemical study. (25400816)
2014
2
Mesonephric adenocarcinoma with a sarcomatous component, a notable subtype of cervical carcinosarcoma: a case report and review of the literature. (23651629)
2013
3
High expressions of bcl-2 and survivin, and decreased apoptosis in uterine cervical carcinosarcoma compared to cervical squamous cell carcinoma. (20668868)
2011
4
A case of uterine cervical carcinosarcoma recurrence who obtained a clinically complete response by ifosfamide, doxorubicin and cisplatin. (21446343)
2011
5
Uterine cervical carcinosarcoma with heterologous mesenchymal component: a case report and review of the literature. (19263060)
2009
6
Cervical carcinosarcoma: a case report. (18357808)
2008
7
Case of uterine cervical carcinosarcoma. (16176508)
2005
8
Cervical carcinosarcoma occurring after subtotal hysterectomy, a case report. (9441782)
1997
9
Cervical carcinosarcoma: a case report. (3957124)
1986

Variations for Cervical Carcinosarcoma

About this section

Expression for genes affiliated with Cervical Carcinosarcoma

About this section
Search GEO for disease gene expression data for Cervical Carcinosarcoma.

Pathways for genes affiliated with Cervical Carcinosarcoma

About this section

Pathways related to Cervical Carcinosarcoma according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1BIRC5, BCL2
2
Show member pathways
9.1BIRC5, BCL2
3
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
9.1BCL2, BIRC5
49.1BIRC5, BCL2
5
Show member pathways
9.1BIRC5, BCL2
6
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
9.1BCL2, BIRC5
7
Show member pathways
Signal transduction PTEN pathway58
9.1BIRC5, BCL2
8
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway58
9.1BIRC5, BCL2
9
Show member pathways
Apoptosis and survival Apoptotic TNF family pathways58
9.1BIRC5, BCL2
109.1BCL2, BIRC5
11
Show member pathways
Apoptosis Modulation and Signaling36
Apoptosis36
9.1BIRC5, BCL2
129.1BIRC5, BCL2

Compounds for genes affiliated with Cervical Carcinosarcoma

About this section

Compounds related to Cervical Carcinosarcoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 63)
idCompoundScoreTop Affiliating Genes
1ponicidin439.6BIRC5, BCL2
2naphtho(1,2-b)furan-4,5-dione439.6BIRC5, BCL2
3betulinic acid43 2810.6BIRC5, BCL2
4hoechst 33342439.6BCL2, BIRC5
5bryostatin 1439.6BIRC5, BCL2
6taxane439.6BIRC5, BCL2
7noxa439.6BCL2, BIRC5
82-chlorodeoxyadenosine439.6BIRC5, BCL2
9indole-3-carbinol439.6BIRC5, BCL2
10dutp439.6BCL2, BIRC5
11sulindac43 1210.6BCL2, BIRC5
12topotecan43 1210.6BIRC5, BCL2
13suberoylanilide hydroxamic acid439.6BCL2, BIRC5
14mitoxantrone43 49 1211.5BIRC5, BCL2
15roscovitine439.5BIRC5, BCL2
16fludarabine43 49 1211.5BIRC5, BCL2
17flavopiridol43 1210.5BCL2, BIRC5
18rituximab43 49 1211.5BIRC5, BCL2
19daunorubicin43 49 1211.5BIRC5, BCL2
20vinblastine43 49 1211.5BCL2, BIRC5
21celecoxib43 59 28 49 24 1214.5BIRC5, BCL2
22bortezomib43 49 1211.5BIRC5, BCL2
23pdtc439.5BCL2, BIRC5
24adpribose439.5BIRC5, BCL2
25gemcitabine43 49 1211.5BIRC5, BCL2
26mitomycin c439.5BCL2, BIRC5
27lactacystin439.5BIRC5, BCL2
28thymidylate439.5BIRC5, BCL2
29vincristine43 49 1211.5BCL2, BIRC5
30resveratrol43 59 24 1212.5BIRC5, BCL2
31adriamycin439.5BIRC5, BCL2
32troglitazone43 28 59 1212.5BCL2, BIRC5
33camptothecin43 59 1211.5BIRC5, BCL2
34docetaxel43 49 59 1212.4BIRC5, BCL2
35egcg439.4BCL2, BIRC5
36mg 13243 5910.4BIRC5, BCL2
37quercetin43 59 24 1212.4BIRC5, BCL2
38imatinib43 49 1211.4BCL2, BIRC5
39curcumin439.4BIRC5, BCL2
40arsenite43 2410.4BIRC5, BCL2
415fluorouracil439.4BCL2, BIRC5
42etoposide43 49 59 1212.3BIRC5, BCL2
43n acetylcysteine439.3BIRC5, BCL2
44sb 20358043 5910.3BCL2, BIRC5
45butyrate439.2BIRC5, BCL2
46tamoxifen43 49 28 1212.2BIRC5, BCL2
47paclitaxel43 49 1211.1BCL2, BIRC5
48ly294002439.1BIRC5, BCL2
49rapamycin439.0BIRC5, BCL2
50pd 98,059438.8BIRC5, BCL2

GO Terms for genes affiliated with Cervical Carcinosarcoma

About this section

Biological processes related to Cervical Carcinosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1apoptotic processGO:00069159.1BIRC5, BCL2
2negative regulation of apoptotic processGO:00430668.8BIRC5, BCL2

Molecular functions related to Cervical Carcinosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein homodimerization activityGO:00428039.1BIRC5, BCL2
2protein heterodimerization activityGO:00469829.0BIRC5, BCL2
3identical protein bindingGO:00428028.8BIRC5, BCL2

Products for genes affiliated with Cervical Carcinosarcoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Cervical Carcinosarcoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet