MCID: CRV038
MIFTS: 53

Cervical Squamous Cell Carcinoma malady

Reproductive diseases, Cancer diseases, Rare diseases categories

Summaries for Cervical Squamous Cell Carcinoma

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Disease Ontology:9 A cervix carcinoma that has material basis in squamous cells of the cervix.

MalaCards based summary: Cervical Squamous Cell Carcinoma, also known as squamous cell carcinoma of the cervix uteri, is related to cervical intraepithelial neoplasia and adenosquamous carcinoma. An important gene associated with Cervical Squamous Cell Carcinoma is SERPINB3 (serpin peptidase inhibitor, clade B (ovalbumin), member 3), and among its related pathways are Cytoskeleton remodeling Keratin filaments and Matrix Metalloproteinases. The compounds calcipotriol and ethylenediaminetetraacetic acid have been mentioned in the context of this disorder. Affiliated tissues include uterus, skeletal muscle and cervix, and related mouse phenotypes are hearing/vestibular/ear and craniofacial.

Aliases & Classifications for Cervical Squamous Cell Carcinoma

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Sources:
30LifeMap Discovery®, 9Disease Ontology, 11DISEASES, 43Novoseek, 47Orphanet, 60UMLS, 38NCIt, 55SNOMED-CT, 26ICD10 via Orphanet
See all sources

Cervical Squamous Cell Carcinoma, Aliases & Descriptions:

Name: Cervical Squamous Cell Carcinoma 30 9 11 43 47 60
Squamous Cell Carcinoma of the Cervix Uteri 9 47
 
Squamous Cell Carcinoma of Cervix 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Reproductive diseases


External Ids:

Disease Ontology9 DOID:3744
NCIt38 C4028
SNOMED-CT55 254886006
Orphanet47 213767
ICD10 via Orphanet26 C53

Related Diseases for Cervical Squamous Cell Carcinoma

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Diseases related to Cervical Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 88)
idRelated DiseaseScoreTop Affiliating Genes
1cervical intraepithelial neoplasia30.9TP73, KRT8, KRT10
2adenosquamous carcinoma30.8TYMP, KRT8
3papilloma30.0RASSF1, KRT10, TP73, KRT14
4adenocarcinoma28.8KRT8, KRT14, TP73, KRT10, SERPINB3, TYMP
5cervicitis11.4
6microinvasive cervical squamous cell carcinoma10.6
7neuroendocrine carcinoma10.4
8small cell neuroendocrine carcinoma10.4
9cardiac tamponade10.4
10keratoacanthoma10.4
11serous cystadenocarcinoma10.3TYMP, MMP14
12keratinizing squamous cell carcinoma10.3
13fibrous histiocytoma10.3
14anal squamous cell carcinoma10.3
15histiocytoma10.3
16sarcoma10.3
17bowen syndrome10.3KRT14, KRT10
18palmoplantar keratoderma, nonepidermolytic10.3KRT14, KRT10
19epidermolysis bullosa simplex10.3KRT14, KRT10
20pancreatic ductal carcinoma10.3TYMP, KRT8
21laryngeal carcinoma10.2SERPINB3, MMP14
22cholesteatoma10.2KRT14, KRT10
23endocervicitis10.2
24breast adenocarcinoma10.2
25cervical carcinosarcoma10.2
26dermatomyositis10.2
27endometrial adenocarcinoma10.2
28vaginitis10.2
29neuroendocrine carcinoma of the cervix10.2
30craniopharyngioma10.2KRT8, KRT14
31chordoma10.2KRT14, KRT8
32angiosarcoma10.2KRT8, KRT14
33ameloblastoma10.2KRT8, KRT14
34cervical adenocarcinoma10.2KRT8, RASSF1
35skin disease10.2KRT10, KRT14, CD40
36bladder cancer, somatic10.1SERPINB3, RASSF1
37abdominal aortic aneurysm10.1MMP14, TIMP2
38plasma cell leukemia10.1TP73, CD40
39breast ductal carcinoma10.1KRT8, TIMP2
40keloids10.1TIMP2, KRT14
41psoriasis10.1KRT14, CD40, KRT10, SERPINB3
42endometriosis10.1TIMP2, MMP14, TYMP
43gallbladder cancer10.0KRT8, TIMP2, TYMP
44kidney cancer10.0TYMP, RASSF1
45oxyphilic adenoma10.0KRT14, RASSF1, KRT8
46sarcoma, synovial10.0KRT8, RASSF1, KRT14
47hepatitis b10.0SERPINB3, TYMP, MMP14, KRT8
48adenomatous polyposis coli10.0MMP14, DAPK1, RASSF1
49cholangiocarcinoma10.0RASSF1, DAPK1, KRT8
50hepatitis10.0TIMP2, KRT8

Graphical network of the top 20 diseases related to Cervical Squamous Cell Carcinoma:



Diseases related to cervical squamous cell carcinoma

Symptoms for Cervical Squamous Cell Carcinoma

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Drugs & Therapeutics for Cervical Squamous Cell Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Cervical Squamous Cell Carcinoma

Search NIH Clinical Center for Cervical Squamous Cell Carcinoma

Genetic Tests for Cervical Squamous Cell Carcinoma

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Anatomical Context for Cervical Squamous Cell Carcinoma

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MalaCards organs/tissues related to Cervical Squamous Cell Carcinoma:

31
Uterus, Skeletal muscle, Cervix, Brain, Lymph node, Breast, Heart, Liver, Prostate, T cells, B cells, Ovary, Placenta, Testes, Lung, Skin, Testis

Animal Models for Cervical Squamous Cell Carcinoma or affiliated genes

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MGI Mouse Phenotypes related to Cervical Squamous Cell Carcinoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053778.7KRT10, MMP14, TP73, KRT14
2MP:00053828.6KRT14, KRT10, MMP14, TP73
3MP:00020068.1KRT14, KRT10, RASSF1, TP73
4MP:00053977.5MMP14, TP73, KRT8, KRT14, CD40, TIMP2
5MP:00053847.5RASSF1, KRT14, MMP14, TP73, TYMP, DAPK1
6MP:00036317.4TIMP2, TP73, TYMP, DAPK1, MMP14, CD40
7MP:00053766.7RASSF1, MMP14, TP73, TYMP, DAPK1, KRT14
8MP:00053876.5RASSF1, TYMP, TP73, KRT14, CD40, MMP14

Publications for Cervical Squamous Cell Carcinoma

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Articles related to Cervical Squamous Cell Carcinoma:

(show top 50)    (show all 245)
idTitleAuthorsYear
1
EGFR Promoter Methylation, EGFR Mutation, and HPV Infection in Chinese Cervical Squamous Cell Carcinoma. (25789535)
2015
2
Cervical squamous cell carcinoma with isolated tibial metastasis: A case report and review of the literature. (25364422)
2014
3
Oncostatin M receptor is a novel therapeutic target in cervical squamous cell carcinoma. (24659184)
2014
4
IMP3 expression is associated with poor survival in cervical squamous cell carcinoma. (25176620)
2014
5
Differentially expressed microRNAs in the serum of cervical squamous cell carcinoma patients before and after surgery. (24405714)
2014
6
Heat shock protein 70 is involved in malignant behaviors and chemosensitivities to cisplatin in cervical squamous cell carcinoma cells. (24689999)
2014
7
Expression of CDC42 in cervical squamous cell carcinoma and its correlation with clinicopathologic characteristics. (24385692)
2013
8
Case of metastatic uterine cervical squamous cell carcinoma in the right atrium. (23564576)
2013
9
Primary Squamous Cell Carcinoma of the Upper Genital Tract: Utility of p16(INK4a) Expression and HPV DNA Status in its Differential Diagnosis from Extended Cervical Squamous Cell Carcinoma. (24421848)
2013
10
Genetic variants in interleukin-18 gene and risk for cervical squamous cell carcinoma. (23603311)
2013
11
ERCC1 mRNA levels can predict the response to cisplatin-based concurrent chemoradiotherapy of locally advanced cervical squamous cell carcinoma. (23259415)
2012
12
Screening test results associated with cancer diagnoses in 287 women with cervical squamous cell carcinoma. (22900617)
2012
13
Recurrence during pregnancy of a conservatively treated early-stage cervical squamous cell carcinoma. (20655526)
2011
14
Laparoscopic adrenalectomy for isolated adrenal metastasis from cervical squamous cell carcinoma and endometrial adenocarcinoma. (21664660)
2011
15
Two novel unbalanced whole arm translocations are frequently detected in cervical squamous cell carcinoma. (22285016)
2011
16
Reduced expression of I9I9p63I+ inA cervical squamous cell carcinoma. (21631996)
2011
17
Common genetic polymorphisms in pre-microRNAs and risk of cervical squamous cell carcinoma. (21319225)
2011
18
Influence of lymph vascular space invasion on prognosis of patients with early-stage cervical squamous cell carcinoma. (20346220)
2010
19
Expression of PSCA, PIWIL1 and TBX2 and its correlation with HPV16 infection in formalin-fixed, paraffin-embedded cervical squamous cell carcinoma specimens. (20229117)
2010
20
Significant effects of lymph and blood vascular invasion on the prognosis of early-stage cervical squamous cell carcinoma. (20846259)
2010
21
Plasma proteome analysis of cervical intraepithelial neoplasia and cervical squamous cell carcinoma. (20093745)
2009
22
Cyclooxygenase-2 expression in cervical squamous cell carcinoma: the significance of expression in neoplastic cells within the lymphovascular space. (20192574)
2009
23
Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma. (19638983)
2009
24
Microarray profile of micro-ribonucleic acid in tumor tissue from cervical squamous cell carcinoma without human papillomavirus. (20149030)
2009
25
Comparison of tumor regression rate of uterine cervical squamous cell carcinoma during external beam and intracavitary radiotherapy. (19030960)
2008
26
Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival. (17503414)
2007
27
Early determination of uterine cervical squamous cell carcinoma radioresponse identifies high- and low-response tumors. (16343805)
2006
28
Expression and clinical significance of autophagy gene Beclin 1 in cervical squamous cell carcinoma]. (17236580)
2006
29
EMMPRIN-induced MMP-2 activation cascade in human cervical squamous cell carcinoma. (16425263)
2006
30
HLA-DRB1 alleles and cervical squamous cell carcinoma: experimental study and meta-analysis. (16720214)
2006
31
Tumor lymphangiogenesis in cervical squamous cell carcinoma and its clinical significance]. (16179117)
2005
32
Cell proliferation of bulky cervical squamous cell carcinoma is strongly associated with a paracrine tissue-specific growth factor(s). (16211274)
2005
33
P63 and EGFR as prognostic predictors in stage IIB radiation-treated cervical squamous cell carcinoma. (14599865)
2003
34
Enhanced expression of alpha 2,6-sialyltransferase ST6Gal I in cervical squamous cell carcinoma. (12798701)
2003
35
Overexpression of p16 and p14ARF is associated with human papillomavirus infection in cervical squamous cell carcinoma and dysplasia. (12100520)
2002
36
Chlamydia trachomatis and cervical squamous cell carcinoma. (11277820)
2001
37
Karyometric features differentiate early invasive cervical squamous cell carcinoma from preinvasive carcinoma. (11915180)
2001
38
Increased carcinoembryonic antigen expression in cervical intraepithelial neoplasia grade 3 and in cervical squamous cell carcinoma. (11112209)
2000
39
Relative changes of MIB1 and PC10 labeling indexes in cell kinetics during radiotherapy for cervical squamous cell carcinoma. (9490095)
1997
40
Possible involvement of tumour-derived interleukin-6 in dermatomyositis associated with cervical squamous cell carcinoma. (9115948)
1997
41
Cervical squamous cell carcinoma and its precursor lesions: cytodiagnostic criteria and pitfalls. (9390926)
1996
42
Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor, and c-erbB-2 in early cervical squamous cell carcinoma. An immunohistochemical study. (8697388)
1996
43
Angiogenesis in uterine cervical squamous cell carcinoma. (8601522)
1995
44
Age is prognostic variable in cervical squamous cell carcinoma. (8344321)
1993
45
Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates. (7694891)
1993
46
Expression of ras oncogene product and EGF receptor in cervical squamous cell carcinomas and its relationship to lymph node involvement. (1707025)
1991
47
Keratoacanthomas associated with cervical squamous cell carcinoma. (4004294)
1985
48
Tumor-antigen TA-4 in the detection of recurrence in cervical squamous cell carcinoma. (6478396)
1984
49
Tumor antigen of human cervical squamous cell carcinoma: correlation of circulating levels with disease progress. (421183)
1979
50
Biological properties and radiation responses of the hamster uterine cervical squamous cell carcinoma. (441259)
1979

Variations for Cervical Squamous Cell Carcinoma

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Cosmic variations for Cervical Squamous Cell Carcinoma:

7 (show all 172)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
143896TP53cervix,NS,carcinoma,squamous cell carcinoma3
210648TP53cervix,NS,carcinoma,squamous cell carcinoma3
346185TP53cervix,NS,carcinoma,squamous cell carcinoma3
443660TP53cervix,NS,carcinoma,squamous cell carcinoma3
510725TP53cervix,NS,carcinoma,squamous cell carcinoma3
610889TP53cervix,NS,carcinoma,squamous cell carcinoma3
745507TP53cervix,NS,carcinoma,squamous cell carcinoma3
810662TP53cervix,NS,carcinoma,squamous cell carcinoma3
943662TP53cervix,NS,carcinoma,squamous cell carcinoma3
1010749TP53cervix,NS,carcinoma,squamous cell carcinoma3
1144029TP53cervix,NS,carcinoma,squamous cell carcinoma3
1211356TP53cervix,NS,carcinoma,squamous cell carcinoma3
1310817TP53cervix,NS,carcinoma,squamous cell carcinoma3
1444407TP53cervix,NS,carcinoma,squamous cell carcinoma3
1511483TP53cervix,NS,carcinoma,squamous cell carcinoma3
1643624TP53cervix,NS,carcinoma,squamous cell carcinoma3
1710659TP53cervix,NS,carcinoma,squamous cell carcinoma3
1843878TP53cervix,NS,carcinoma,squamous cell carcinoma3
1945257TP53cervix,NS,carcinoma,squamous cell carcinoma3
2029329PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
211168056PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
22766PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
23249144PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
24773PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
2529328PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
26760PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
27775PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
28763PIK3CAcervix,NS,carcinoma,squamous cell carcinoma3
29555KRAScervix,NS,carcinoma,squamous cell carcinoma3
30552KRAScervix,NS,carcinoma,squamous cell carcinoma3
31551KRAScervix,NS,carcinoma,squamous cell carcinoma3
32521KRAScervix,NS,carcinoma,squamous cell carcinoma3
33518KRAScervix,NS,carcinoma,squamous cell carcinoma3
34517KRAScervix,NS,carcinoma,squamous cell carcinoma3
3512470CDKN2Acervix,NS,carcinoma,squamous cell carcinoma3
3613778CDKN2Acervix,NS,carcinoma,squamous cell carcinoma3
3712469CDKN2Acervix,NS,carcinoma,squamous cell carcinoma3
3813777CDKN2Acervix,NS,carcinoma,squamous cell carcinoma3
39497HRAScervix,NS,carcinoma,squamous cell carcinoma3
40499HRAScervix,NS,carcinoma,squamous cell carcinoma3
41480HRAScervix,NS,carcinoma,squamous cell carcinoma3
42483HRAScervix,NS,carcinoma,squamous cell carcinoma3
435730CTNNB1cervix,NS,carcinoma,squamous cell carcinoma3
445731CTNNB1cervix,NS,carcinoma,squamous cell carcinoma3
455662CTNNB1cervix,NS,carcinoma,squamous cell carcinoma3
46460236ACAP1cervix,NS,carcinoma,squamous cell carcinoma3
47460237ACAP1cervix,NS,carcinoma,squamous cell carcinoma3
48460238ACAP1cervix,NS,carcinoma,squamous cell carcinoma3
49460132PIK3C3cervix,NS,carcinoma,squamous cell carcinoma3
50460131PIK3C3cervix,NS,carcinoma,squamous cell carcinoma3
51462097APCcervix,NS,carcinoma,squamous cell carcinoma3
52462098APCcervix,NS,carcinoma,squamous cell carcinoma3
53459517YAF2cervix,NS,carcinoma,squamous cell carcinoma3
54459518YAF2cervix,NS,carcinoma,squamous cell carcinoma3
55459454HOXC4cervix,NS,carcinoma,squamous cell carcinoma3
56460633HGFACcervix,NS,carcinoma,squamous cell carcinoma3
57460352HNF1Bcervix,NS,carcinoma,squamous cell carcinoma3
58461385ERP44cervix,NS,carcinoma,squamous cell carcinoma3
59459507KDM5Acervix,NS,carcinoma,squamous cell carcinoma3
60460530ESPNcervix,NS,carcinoma,squamous cell carcinoma3
61458881FANK1cervix,NS,carcinoma,squamous cell carcinoma3
62460658FSTL5cervix,NS,carcinoma,squamous cell carcinoma3
63715FGFR3cervix,NS,carcinoma,squamous cell carcinoma3
64462216GATA1cervix,NS,carcinoma,squamous cell carcinoma3
65461618HDAC9cervix,NS,carcinoma,squamous cell carcinoma3
6649175FGFR2cervix,NS,carcinoma,squamous cell carcinoma3
671294421LYNcervix,NS,carcinoma,squamous cell carcinoma3
68460378NF1cervix,NS,carcinoma,squamous cell carcinoma3
69461487MTSS1cervix,NS,carcinoma,squamous cell carcinoma3
70461127NF2cervix,NS,carcinoma,squamous cell carcinoma3
71461297NFE2L2cervix,NS,carcinoma,squamous cell carcinoma3
72459120MAP3K9cervix,NS,carcinoma,squamous cell carcinoma3
73460253KPNA2cervix,NS,carcinoma,squamous cell carcinoma3
74461180ERBB4cervix,NS,carcinoma,squamous cell carcinoma3
75462233MAOAcervix,NS,carcinoma,squamous cell carcinoma3
76461859MAP3K4cervix,NS,carcinoma,squamous cell carcinoma3
77458319KIF21Bcervix,NS,carcinoma,squamous cell carcinoma3
78462255EIF2S3cervix,NS,carcinoma,squamous cell carcinoma3
79461672BRAFcervix,NS,carcinoma,squamous cell carcinoma3
80460894ATRcervix,NS,carcinoma,squamous cell carcinoma3
81460509CDH8cervix,NS,carcinoma,squamous cell carcinoma3
821294548CDKL5cervix,NS,carcinoma,squamous cell carcinoma3
83459012CEP152cervix,NS,carcinoma,squamous cell carcinoma3
84458749CELSR2cervix,NS,carcinoma,squamous cell carcinoma3
85459992CEBPAcervix,NS,carcinoma,squamous cell carcinoma3
86460620ATP8A1cervix,NS,carcinoma,squamous cell carcinoma3
87458660ADAM30cervix,NS,carcinoma,squamous cell carcinoma3
88460976ADAM17cervix,NS,carcinoma,squamous cell carcinoma3
89460700ADAD1cervix,NS,carcinoma,squamous cell carcinoma3
90460710ANK2cervix,NS,carcinoma,squamous cell carcinoma3
911293160ANKRD34Acervix,NS,carcinoma,squamous cell carcinoma3
92460782ARIH2cervix,NS,carcinoma,squamous cell carcinoma3
931294170ARAP3cervix,NS,carcinoma,squamous cell carcinoma3
94462445CIZ1cervix,NS,carcinoma,squamous cell carcinoma3
95460549CREBBPcervix,NS,carcinoma,squamous cell carcinoma3
96461811EHMT2cervix,NS,carcinoma,squamous cell carcinoma3
97462410EHMT1cervix,NS,carcinoma,squamous cell carcinoma3
98461040EIF2B4cervix,NS,carcinoma,squamous cell carcinoma3
99458454EPHA2cervix,NS,carcinoma,squamous cell carcinoma3
100122851EP300cervix,NS,carcinoma,squamous cell carcinoma3
101458659NOTCH2cervix,NS,carcinoma,squamous cell carcinoma3
102462333DOCK11cervix,NS,carcinoma,squamous cell carcinoma3
103460441DIRAS3cervix,NS,carcinoma,squamous cell carcinoma3
104458372CYB5R2cervix,NS,carcinoma,squamous cell carcinoma3
105461766CUL9cervix,NS,carcinoma,squamous cell carcinoma3
106461314CSRNP3cervix,NS,carcinoma,squamous cell carcinoma3
107459139DAAM1cervix,NS,carcinoma,squamous cell carcinoma3
108368264DCAF12L2cervix,NS,carcinoma,squamous cell carcinoma3
1091293978DGKDcervix,NS,carcinoma,squamous cell carcinoma3
110459488DDX23cervix,NS,carcinoma,squamous cell carcinoma3
111459554EPHA8cervix,NS,carcinoma,squamous cell carcinoma3
112460271TANC2cervix,NS,carcinoma,squamous cell carcinoma3
113461320TANC1cervix,NS,carcinoma,squamous cell carcinoma3
114459710TAF4cervix,NS,carcinoma,squamous cell carcinoma3
115460389TAOK1cervix,NS,carcinoma,squamous cell carcinoma3
116461344TFF3cervix,NS,carcinoma,squamous cell carcinoma3
11725844STK11cervix,NS,carcinoma,squamous cell carcinoma3
118459764SPAG4cervix,NS,carcinoma,squamous cell carcinoma3
119460596SMG1cervix,NS,carcinoma,squamous cell carcinoma3
120459682SLC9A4cervix,NS,carcinoma,squamous cell carcinoma3
1211293384SMTNL1cervix,NS,carcinoma,squamous cell carcinoma3
122547547SOX5cervix,NS,carcinoma,squamous cell carcinoma3
123459150SOCS4cervix,NS,carcinoma,squamous cell carcinoma3
124459338SOCS2cervix,NS,carcinoma,squamous cell carcinoma3
125461755TINAGcervix,NS,carcinoma,squamous cell carcinoma3
126460300TNNI3Kcervix,NS,carcinoma,squamous cell carcinoma3
127460293WFIKKN2cervix,NS,carcinoma,squamous cell carcinoma3
128461224WDR75cervix,NS,carcinoma,squamous cell carcinoma3
129460647VEGFCcervix,NS,carcinoma,squamous cell carcinoma3
130462382ZFAND5cervix,NS,carcinoma,squamous cell carcinoma3
131461943ZFYVE16cervix,NS,carcinoma,squamous cell carcinoma3
132460368ZNF830cervix,NS,carcinoma,squamous cell carcinoma3
133459842ZNF776cervix,NS,carcinoma,squamous cell carcinoma3
134458386UVRAGcervix,NS,carcinoma,squamous cell carcinoma3
135462225USP11cervix,NS,carcinoma,squamous cell carcinoma3
136459037TTBK2cervix,NS,carcinoma,squamous cell carcinoma3
137460906TRIM42cervix,NS,carcinoma,squamous cell carcinoma3
1381293258TP73cervix,NS,carcinoma,squamous cell carcinoma3
139458285TXNRD1cervix,NS,carcinoma,squamous cell carcinoma3
140461503UBR5cervix,NS,carcinoma,squamous cell carcinoma3
141458238SBNO1cervix,NS,carcinoma,squamous cell carcinoma3
142459151SAMD4Acervix,NS,carcinoma,squamous cell carcinoma3
143458967PMLcervix,NS,carcinoma,squamous cell carcinoma3
144461820PPP1R10cervix,NS,carcinoma,squamous cell carcinoma3
145459360PPP1R12Acervix,NS,carcinoma,squamous cell carcinoma3
146462360PTCH1cervix,NS,carcinoma,squamous cell carcinoma3
147461574PSPHcervix,NS,carcinoma,squamous cell carcinoma3
148462321PRPS2cervix,NS,carcinoma,squamous cell carcinoma3
149461705PIK3CGcervix,NS,carcinoma,squamous cell carcinoma3
150458302PIK3C2Bcervix,NS,carcinoma,squamous cell carcinoma3
1511294450NUP214cervix,NS,carcinoma,squamous cell carcinoma3
152460102ZNHIT6cervix,NS,carcinoma,squamous cell carcinoma3
153458281NUAK1cervix,NS,carcinoma,squamous cell carcinoma3
154458436PCcervix,NS,carcinoma,squamous cell carcinoma3
155462038PDGFRBcervix,NS,carcinoma,squamous cell carcinoma3
156419633PI4KAP2cervix,NS,carcinoma,squamous cell carcinoma3
1571293555PDILTcervix,NS,carcinoma,squamous cell carcinoma3
158460778RHOAcervix,NS,carcinoma,squamous cell carcinoma3
159458827RBP3cervix,NS,carcinoma,squamous cell carcinoma3
160460768RBM5cervix,NS,carcinoma,squamous cell carcinoma3
161462045RNF14cervix,NS,carcinoma,squamous cell carcinoma3
162461889RNF182cervix,NS,carcinoma,squamous cell carcinoma3
163458581S100A1cervix,NS,carcinoma,squamous cell carcinoma3
1641294091RNF7cervix,NS,carcinoma,squamous cell carcinoma3
165461571RNF216cervix,NS,carcinoma,squamous cell carcinoma3
166460070RAB3Dcervix,NS,carcinoma,squamous cell carcinoma3
167461145RAB36cervix,NS,carcinoma,squamous cell carcinoma3
168460085PTPRMcervix,NS,carcinoma,squamous cell carcinoma3
1695089PTENcervix,NS,carcinoma,squamous cell carcinoma3
1701293252PTPRUcervix,NS,carcinoma,squamous cell carcinoma3
1711294014RAB22Acervix,NS,carcinoma,squamous cell carcinoma3
172580NRAScervix,NS,carcinoma,squamous cell carcinoma3

Expression for genes affiliated with Cervical Squamous Cell Carcinoma

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LifeMap Discovery
Genes differentially expressed in tissues of Cervical Squamous Cell Carcinoma patients vs. healthy controls: 30 (show all 70)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1KRT1keratin 1Uterus-5.470.000
2KRTDAPkeratinocyte differentiation-associated proteinUterus-4.960.000
3CTHRC1collagen triple helix repeat containing 1Uterus+4.650.000
4TMPRSS11Btransmembrane protease, serine 11BUterus-4.580.000
5CDKN2Acyclin-dependent kinase inhibitor 2AUterus+4.450.000
6CMPK2cytidine monophosphate (UMP-CMP) kinase 2, mitochondrialUterus+4.320.000
7CRNNcornulinUterus-4.250.000
8MALmal, T-cell differentiation proteinUterus-4.210.000
9DSG1desmoglein 1Uterus-4.170.000
10ECT2epithelial cell transforming 2Uterus+4.100.000
11SYCP2synaptonemal complex protein 2Uterus+3.950.000
12HS6ST2heparan sulfate 6-O-sulfotransferase 2Uterus+3.940.000
13KIF14kinesin family member 14Uterus+3.880.000
14IFI44interferon-induced protein 44Uterus+3.880.000
15MMP1matrix metallopeptidase 1 (interstitial collagenase)Uterus+3.830.001
16GREB1growth regulation by estrogen in breast cancer 1Uterus-3.780.000
17KRT17keratin 17Uterus+3.710.000
18SPINK7serine peptidase inhibitor, Kazal type 7 (putative)Uterus-3.700.000
19NUF2NUF2, NDC80 kinetochore complex componentUterus+3.700.000
20NCEH1neutral cholesterol ester hydrolase 1Uterus+3.640.000
21PLSCR1phospholipid scramblase 1Uterus+3.630.000
22E2F7E2F transcription factor 7Uterus+3.620.000
23ANKRD32ankyrin repeat domain 32Uterus+3.610.000
24INHBAinhibin, beta AUterus+3.590.001
25DAPL1death associated protein-like 1Uterus-3.570.000
26KRT4keratin 4Uterus-3.530.000
27SMC4structural maintenance of chromosomes 4Uterus+3.500.000
28CEP55centrosomal protein 55kDaUterus+3.490.000
29LOXlysyl oxidaseUterus+3.480.000
30ANLNanillin, actin binding proteinUterus+3.480.000
31ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)Uterus+3.460.000
32CRISP3cysteine-rich secretory protein 3Uterus-3.460.001
33HELLShelicase, lymphoid-specificUterus+3.440.000
34KRT19keratin 19Uterus+3.440.002
35SPP1secreted phosphoprotein 1Uterus+3.430.000
36CNFNcornifelinUterus-3.420.000
37EPCAMepithelial cell adhesion moleculeUterus+3.390.000
38NDC80NDC80 kinetochore complex componentUterus+3.350.000
39SCDstearoyl-CoA desaturase (delta-9-desaturase)Uterus+3.310.000
40CRCT1cysteine-rich C-terminal 1Uterus-3.310.002
41KRT13keratin 13Uterus-3.300.010
42CDK1cyclin-dependent kinase 1Uterus+3.300.000
43DDIT4DNA-damage-inducible transcript 4Uterus+3.290.000
44C6orf211chromosome 6 open reading frame 211Uterus+3.290.000
45ALOX12arachidonate 12-lipoxygenaseUterus-3.280.000
46ATAD2ATPase family, AAA domain containing 2Uterus+3.270.000
47ZIC2Zic family member 2Uterus+3.260.000
48ARHGAP21Rho GTPase activating protein 21Uterus+3.240.000
49LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homologUterus+3.240.000
50PPIBpeptidylprolyl isomerase B (cyclophilin B)Uterus+3.230.000
51CSTF3cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDaUterus+3.200.000
52TFRCtransferrin receptorUterus+3.190.000
53TOP2Atopoisomerase (DNA) II alpha 170kDaUterus+3.180.000
54S100A8S100 calcium binding protein A8Uterus-3.180.000
55ASPMasp (abnormal spindle) homolog, microcephaly associated (Drosophila)Uterus+3.160.000
56B4GALT4UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4Uterus+3.150.000
57EDN3endothelin 3Uterus-3.150.000
58IL8interleukin 8Uterus+3.140.000
59RAD51AP1RAD51 associated protein 1Uterus+3.120.000
60HNRNPH2heterogeneous nuclear ribonucleoprotein H2 (H')Uterus+3.120.000
61DTLdenticleless E3 ubiquitin protein ligase homolog (Drosophila)Uterus+3.120.000
62NASPnuclear autoantigenic sperm protein (histone-binding)Uterus+3.090.000
63ESRGembryonic stem cell related (non-protein coding)Uterus-3.070.000
64CENPKcentromere protein KUterus+3.060.000
65PLATplasminogen activator, tissueUterus+3.040.000
66SPINK5serine peptidase inhibitor, Kazal type 5Uterus-3.030.000
67TMEFF2transmembrane protein with EGF-like and two follistatin-like domains 2Uterus-3.020.000
68EREGepiregulinUterus-3.020.000
69ISG15ISG15 ubiquitin-like modifierUterus+3.010.001
70KNTC1kinetochore associated 1Uterus+3.010.000

Search GEO for disease gene expression data for Cervical Squamous Cell Carcinoma.

Pathways for genes affiliated with Cervical Squamous Cell Carcinoma

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Pathways related to Cervical Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6KRT14, KRT8
2
Show member pathways
9.5MMP14, TIMP2
3
Show member pathways
Signaling Pathways in Glioblastoma36
9.1RASSF1, TYMP, DAPK1

Compounds for genes affiliated with Cervical Squamous Cell Carcinoma

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Compounds related to Cervical Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 68)
idCompoundScoreTop Affiliating Genes
1calcipotriol43 59 28 1212.9KRT14, KRT10
2ethylenediaminetetraacetic acid439.7MMP14, TIMP2
3cytochalasin439.7TIMP2, MMP14
4hematoxylin439.7KRT8, KRT10, KRT14
5sodium bisulfite439.6DAPK1, RASSF1
6p00001439.6MMP14, TIMP2, TYMP
75-methylcytosine43 2410.5DAPK1, RASSF1
8cytosine43 2410.5RASSF1, KRT14, TYMP
9crcs439.5TYMP, RASSF1, DAPK1
10herbimycin a43 5910.4CD40, TIMP2, MMP14
11bromodeoxyuridine439.4MMP14, KRT10, KRT14, KRT8
12retinoid439.3KRT8, KRT14, KRT10
13glyceraldehyde 3-phosphate439.2MMP14, TIMP2, TYMP, KRT10
14methotrexate49 43 1211.2CD40, TIMP2, TYMP
1512-o-tetradecanoylphorbol 13-acetate439.2MMP14, CD40, TIMP2, TYMP
16ly294002439.1TYMP, CD40, MMP14, TIMP2
17thymidine43 2410.1CD40, MMP14, TIMP2, TYMP
18matrigel439.1KRT8, TYMP, MMP14, TIMP2
19paclitaxel43 49 1211.1TIMP2, CD40, KRT8, TYMP
20o6-methylguanine439.0DAPK1, RASSF1, TP73
21tamoxifen43 49 28 1212.0KRT8, TIMP2, TYMP, KRT14
22creatinine439.0TYMP, TIMP2, KRT8, CD40
23butyrate439.0TIMP2, KRT8, KRT14, CD40
24genistein43 28 59 2 24 1214.0CD40, KRT8, MMP14, TIMP2
25chloramphenicol43 2 49 1211.9TP73, MMP14, KRT14, CD40
26cholesterol43 28 24 1211.9CD40, TIMP2, MMP14, KRT14
27doxorubicin43 49 1210.9TYMP, TP73, CD40, KRT8
28agar438.8RASSF1, MMP14, KRT8
29steroid438.8CD40, KRT10, KRT8, TIMP2
30azathioprine43 2 49 1211.8TP73, RASSF1, TIMP2
31p002438.8TP73, TYMP, TIMP2, MMP14
32cycloheximide438.7TIMP2, MMP14, CD40, TYMP, KRT8
335fluorouracil438.6TP73, TIMP2, TYMP
345-aza-2deoxycytidine438.4TIMP2, TP73, DAPK1, RASSF1
35cisplatin43 49 59 1211.4RASSF1, KRT8, KRT14, TP73, TYMP
36glucose438.4CD40, TYMP, TIMP2, KRT8, KRT14, MMP14
37p003438.3CD40, TIMP2, RASSF1, TP73, TYMP
38cysteine438.1KRT8, KRT14, SERPINB3, TYMP, MMP14, TIMP2
39actinomycin d438.0MMP14, KRT8, TYMP, CD40, TIMP2, TP73
40vegf438.0KRT8, MMP14, TYMP, TIMP2, CD40, TP73
41lipid437.8MMP14, TP73, TIMP2, KRT8, KRT14, CD40
42calcium43 49 24 1210.8MMP14, CD40, KRT8, KRT14, KRT10, TIMP2
43oligonucleotide437.8KRT8, TP73, RASSF1, MMP14, TIMP2, CD40
44paraffin437.3KRT10, KRT8, MMP14, CD40, TYMP, TP73
45progesterone43 28 59 24 1211.3TP73, TIMP2, MMP14, KRT10, KRT14, CD40
46tyrosine437.3TYMP, TP73, TIMP2, MMP14, KRT14, KRT10
47threonine437.2CD40, KRT14, KRT10, KRT8, MMP14, TP73
48retinoic acid43 247.9TIMP2, KRT8, KRT10, RASSF1, KRT14, CD40
49serine436.8KRT8, KRT10, KRT14, CD40, RASSF1, MMP14
50estrogen436.6KRT8, MMP14, TP73, KRT10, DAPK1, RASSF1

GO Terms for genes affiliated with Cervical Squamous Cell Carcinoma

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Cellular components related to Cervical Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:00450959.3KRT10, KRT14, KRT8
2intermediate filamentGO:00058829.2KRT10, KRT8, KRT14
3extracellular spaceGO:00056158.9TIMP2, SERPINB3, KRT10, CD40
4extracellular vesicular exosomeGO:00700628.4CD40, KRT8, KRT10, KRT14, SERPINB3
5cytoplasmGO:00057377.3DAPK1, SERPINB3, MMP14, RASSF1, KRT8, KRT10

Biological processes related to Cervical Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of proteolysisGO:00458619.6SERPINB3, TIMP2

Molecular functions related to Cervical Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055156.4CD40, KRT14, KRT8, RASSF1, MMP14, TIMP2

Products for genes affiliated with Cervical Squamous Cell Carcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Cervical Squamous Cell Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet