MCID: CRV039
MIFTS: 58

Cervicitis malady

Reproductive diseases category
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Summaries for Cervicitis

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Wikipedia:65 Cervicitis is inflammation of the uterine cervix. Cervicitis in women has many features in common with... more...

MalaCards based summary: Cervicitis, also known as cervicitis and endocervicitis, is related to leprosy and multiple sclerosis. An important gene associated with Cervicitis is HSPD1 (heat shock 60kDa protein 1 (chaperonin)), and among its related pathways are Validated targets of C-MYC transcriptional activation and Signaling by Interleukins. The compounds cdcl2 and amp-pnp have been mentioned in the context of this disorder. Affiliated tissues include lymph node, spinal cord and cervix, and related mouse phenotype mortality/aging.

Aliases & Classifications for Cervicitis

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Sources:
8Disease Ontology, 44Novoseek, 62UMLS, 57SNOMED-CT, 34MeSH, 39NCIt
See all sources

Cervicitis, Aliases & Descriptions:

Name: Cervicitis 8 44
Cervicitis and Endocervicitis 8
 
Uterine Cervicitis 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


Related Diseases for Cervicitis

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Diseases in the Cervicitis family:

Acute Cervicitis Chronic Cervicitis

Diseases related to Cervicitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 1194)
idRelated DiseaseScoreTop Affiliating Genes
1leprosy30.5IL2
2multiple sclerosis30.1IL2, IL2RA, HSPD1
3diabetes mellitus30.1HSPD1, HSPA4
4vulvovaginitis30.0HSPA4, HSPD1
5rheumatoid arthritis30.0IL2, IL2RA, HSPD1
6sarcoidosis29.9IL2RA, IL2, HSPA4
7tuberculosis29.9IL2RA, HSPD1, HSPA4, IL2
8melanoma29.9HSPD1, HSPA4, IL2
9leukemia29.8IL2, IL2RA, HSPA4
10severe combined immunodeficiency29.8IL2RA, IL2
11cataract29.7HSPD1, HSPA4
12hepatitis b29.6IL2, HSPA4
13mycosis fungoides29.6IL2RA, IL2
14graft versus host disease29.6IL2RA, IL2
15diphtheria29.6IL2, IL2RA
16eosinophilia29.6IL2RA, IL2
17behcet's disease29.5IL2RA, HSPD1
18hodgkin's lymphoma29.5HSPA4, IL2, IL2RA
19chronic lymphocytic leukemia29.5IL2RA, IL2
20systemic lupus erythematosus29.4HSPD1, IL2, IL2RA
21t-cell leukemia29.4IL2, IL2RA
22tetanus29.2IL2RA, HSPD1, IL2
23cervical cancer11.3
24cervical intraepithelial neoplasia11.1
25dystonia11.0
26cervical dystonia11.0
27spondylosis11.0
28adenocarcinoma11.0
29cervical adenocarcinoma10.9
30cervical squamous cell carcinoma10.9
31radiculopathy10.9
32cervical incompetence10.8
33vaginitis10.7
34cervical adenitis10.7
35lymphadenitis10.7
36thyroiditis10.7
37papilloma10.6
38spinal cord injury10.6
39dysphagia10.6
40epidural abscess10.6
41degenerative disc disease10.6
42quadriplegia10.6
43whiplash10.6
44chronic cervicitis10.6
45adenocarcinoma in situ10.6
46klippel-feil syndrome10.5
47endotheliitis10.5
48fasciitis10.5
49midline cervical cleft10.5
50blindness10.5

Graphical network of the top 20 diseases related to Cervicitis:



Diseases related to cervicitis

Symptoms for Cervicitis

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Drugs & Therapeutics for Cervicitis

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Drug clinical trials:

Search ClinicalTrials for Cervicitis

Search NIH Clinical Center for Cervicitis

Genetic Tests for Cervicitis

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Anatomical Context for Cervicitis

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MalaCards organs/tissues related to Cervicitis:

32
Lymph node, Spinal cord, Cervix, Testes, Thyroid, Endothelial, Bone, Breast, Brain, T cells, Uterus, Tongue, Lung, Thymus, Colon, Placenta, Tonsil, Ovary, Salivary gland, Monocytes, Prostate, Cortex, Liver, Skin, Globus pallidus, B cells, Neutrophil, Bone marrow, Smooth muscle, Myeloid, Subthalamic nucleus, Pineal, Pituitary, Heart, Small intestine, Nk cells, Medulla oblongata, Trachea, Cerebellum, Kidney, Testis, Occipital lobe, Pons, Appendix

Animal Models for Cervicitis or affiliated genes

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MGI Mouse Phenotypes related to Cervicitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107688.0IL2RA, IL2, HSPA4, HSPD1

Publications for Cervicitis

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Articles related to Cervicitis:

(show top 50)    (show all 9177)
idTitleAuthorsYear
1
Successful treatment of cervical incompetence using a modified laparoscopic cervical cerclage technique: a cohort study. (24965992)
2014
2
The clinical utility of botulinum toxin injections targeted at the motor endplate zone in cervical dystonia. (25060697)
2014
3
A headset method for measuring the visual temporal discrimination threshold in cervical dystonia. (25126450)
2014
4
Cytotoxic function of gamma delta (gamma/delta) T cells against pamidronate-treated cervical cancer cells. (24228383)
2013
5
Promoters of and barriers to cervical cancer screening in a rural setting in Tanzania. (24095307)
2013
6
The synthetic flavonoid WYC02-9 inhibits cervical cancer cell migration/invasion and angiogenesis via MAPK14 signaling. (24145114)
2013
7
Women whose cervical intraepithelial neoplasia has been treated or resolved remain at continued high risk for cervical cancer. (23378629)
2013
8
Cervical rib resulting in amaurosis fugax and stroke. (24035686)
2013
9
The nuclear protein expression levels of SNAI1 and ZEB1 are involved in the progression and lymph node metastasis of cervical cancer via the epithelial-mesenchymal transition pathway. (23791009)
2013
10
Nogo-B promotes the epithelial-mesenchymal transition in HeLa cervical cancer cells via Fibulin-5. (23042479)
2013
11
Cellular retinol binding protein 1 could be a tumor suppressor gene in cervical cancer. (24040446)
2013
12
Effect of Rac1 downregulation mediated by shRNA on the biological behaviour of human cervical cancer cells. (23760915)
2013
13
Multilevel anterior cervical discectomy and fusion with and without rhBMP-2: a comparison of dysphagia rates and outcomes in 150 patients. (23157278)
2013
14
The optimized acupuncture treatment for neck pain caused by cervical spondylosis: a study protocol of a multicentre randomized controlled trial. (22776567)
2012
15
Neurofibroma of the cervix presenting as cervical stenosis in a patient with neurofibromatosis type 1: a case report. (22317879)
2012
16
Cervical metastasis of germ cell tumors: evaluation, management, complications, and outcomes. (22252920)
2012
17
Temporary endovascular balloon occlusion of the bilateral internal iliac arteries to control hemorrhage during laparoscopic-assisted vaginal hysterectomy for cervical myoma. (21658835)
2011
18
Somatosensory temporal discrimination tested in patients receiving botulinum toxin injection for cervical dystonia. (21506155)
2011
19
Quality of life among Thai women diagnosed with cervical cancer and cervical intraepithelial neoplasia at King Chulalongkorn Memorial Hospital. (21863670)
2011
20
Bacterial vaginosis is associated with uterine cervical human papillomavirus infection: a meta-analysis. (21223574)
2011
21
Cytokine serum levels in patients with cervical intraepithelial neoplasia grade II-III treated with intralesional interferon-I+ 2b. (22158487)
2011
22
Case report: Langerhans cell histiocytosis presenting as massive cervical adenopathy and retropharyngeal thickening: importance of chest radiography and coordinated airway and anesthetic management. (20145506)
2010
23
Increased serum progesterone and estradiol correlate to increased COX-2 tissue expression in cervical intraepithelial neoplasia. (20530431)
2010
24
Chinese herbal medicine for chronic neck pain due to cervical degenerative disc disease. (20091597)
2010
25
Postoperative adjuvant chemotherapy for node-positive cervical adenocarcinoma. (19396009)
2009
26
Ectopic thymus presenting as a right-side cervical mass in an infant. (18839165)
2009
27
Promoter methylation of DAPK gene in cervical carcinoma]. (18799028)
2008
28
Cervical radiculopathy secondary to Hodgkin's lymphoma. (17445629)
2007
29
Molecular profiling of cervical cancer progression. (17242701)
2007
30
Evaluation of matrix metalloproteinase 2 expression in cervical carcinogenesis using tissue array and integrated optical density for immunoreactivity. (18000234)
2007
31
Cervical interlaminar epidural steroid injection for neck pain and cervical radiculopathy: effect and prognostic factors. (17340166)
2007
32
Radiological grading of cervical destructive spondyloarthropathy in long-term hemodialysis patients. (16891979)
2006
33
Polymorphic amino acids at codons 9 and 37 of HLA-DQB1 alleles may confer susceptibility to cervical cancer among Chinese women. (16425277)
2006
34
A shift to a peripheral Th2-type cytokine pattern during the carcinogenesis of cervical cancer becomes manifest in CIN III lesions. (16189158)
2005
35
Pro-apoptotic efficiencies of three reconstructed human caspase-8 on cervical cancer cell line HeLa]. (15694025)
2005
36
Mental retardation in a boy with anterior cervical hypertrichosis. (15800907)
2005
37
Increased apoptosis in cervical intraepithelial neoplasia associated with HIV infection: implication of oncogenic human papillomavirus, caspases, and Langerhans cells. (15814619)
2005
38
Congenital cervical neuroblastoma. (15390353)
2004
39
A recurrent intradural cervical neurenteric cyst operated on using an anterior approach: a case report. (12633954)
2003
40
Cervical lymphadenopathy caused by Kikuchi disease: positron emission tomographic appearance. (12642715)
2003
41
Telomerase activation in cervical keratinocytes containing stably replicating human papillomavirus type 16 episomes. (12359427)
2002
42
Diagnosis and treatment of intramedullary hemangioblastoma of cervical spinal cord. (12150732)
2002
43
Neonatal cervical osteomyelitis with paraspinal abscess and Erb's palsy. A case report and brief review of the literature. (10965268)
2000
44
Adenocarcinoma in situ with a small cell (endometrioid) pattern in cervical smears: a test of the distinction from benign mimics using specific criteria. (10536349)
1999
45
Secretory leukocyte protease inhibitor (SLPI) concentrations in cervical mucus of women with normal menstrual cycle. (10381821)
1999
46
Prolapsed ovarian cyst through cervical stump: a rare complication of a subtotal hysterectomy. (15512157)
1998
47
Aneurysm of the transverse cervical artery occurring in association with a cavernous hemangioma as a complication of Klippel-TrAcnaunay syndrome: report of a case. (8640026)
1995
48
Molecular biological study on the overexpression of c-myc gene in uterine cervical carcinomas]. (1619315)
1992
49
Cervical instability as an unusual manifestation of Hajdu-Cheney syndrome of acroosteolysis. (2347142)
1990
50
Oral lymphogranuloma venereum and cervical lymphadenopathy. Case report. (4204816)
1974

Variations for Cervicitis

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Expression for genes affiliated with Cervicitis

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Expression patterns in normal tissues for genes affiliated with Cervicitis

Search GEO for disease gene expression data for Cervicitis.

Pathways for genes affiliated with Cervicitis

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Pathways related to Cervicitis according to GeneCards/GeneDecks:

(show all 19)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4HSPD1, HSPA4
2
Show member pathways
9.0IL2RA, IL2
3
Show member pathways
Immune response IL 22 signaling pathway60
G protein signaling N RAS regulation pathway60
9.0IL2RA, IL2
4
Show member pathways
9.0IL2RA, IL2
5
Show member pathways
9.0IL2, IL2RA
6
Show member pathways
9.0IL2RA, IL2
79.0IL2RA, IL2
8
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway60
9.0IL2RA, IL2
9
Show member pathways
Type III interferon signaling37
9.0IL2RA, IL2
10
Show member pathways
Immune response IL 12 induced IFN gamma production60
9.0IL2, IL2RA
119.0IL2RA, IL2
129.0IL2RA, IL2
13
Show member pathways
9.0IL2, IL2RA
14
Show member pathways
IL2 signaling events mediated by STAT537
9.0IL2, IL2RA
15
Show member pathways
Ras signaling in the CD4+ TCR pathway37
9.0IL2RA, IL2
16
Show member pathways
Immune response IL 3 activation and signaling pathway60
9.0IL2RA, IL2
17
Show member pathways
IL-2 Signaling pathway37
9.0IL2, IL2RA
18
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
9.0IL2RA, IL2
19
Show member pathways
8.0IL2RA, IL2, HSPA4, HSPD1

Compounds for genes affiliated with Cervicitis

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Compounds related to Cervicitis according to GeneCards/GeneDecks:

(show top 50)    (show all 77)
idCompoundScoreTop Affiliating Genes
1cdcl2449.8HSPD1, HSPA4
2amp-pnp28 4410.8HSPA4, HSPD1
3tuberculin449.7HSPD1, IL2RA
4toxin-1449.5IL2, HSPD1
5nitrate449.5IL2RA, HSPD1
6rrna449.5IL2RA, HSPD1
7mizoribine449.5IL2, IL2RA
8denileukin diftitox44 50 1111.5IL2RA, IL2
9pentostatin44 61 28 1112.5IL2, IL2RA
10c-d4t449.5IL2RA, IL2
11git 27619.4IL2RA, IL2
124-ipp619.4IL2RA, IL2
13daclizumab44 1110.4IL2, IL2RA
14basiliximab44 1110.4IL2, IL2RA
15gold sodium thiomalate449.4IL2, IL2RA
16alemtuzumab44 1110.4IL2RA, IL2
17pirfenidone44 6110.4IL2, IL2RA
18levamisole44 1110.4IL2RA, IL2
19as 10144 6110.4IL2RA, IL2
20ranitidine44 28 24 1112.4IL2RA, IL2
21mycophenolic acid44 50 1111.4IL2RA, IL2
22okt3449.3IL2, IL2RA
232-chlorodeoxyadenosine449.3IL2RA, IL2
24con a449.3IL2RA, IL2
25sodium arsenite449.3IL2RA, HSPA4, HSPD1
26malondialdehyde449.3HSPD1, HSPA4, IL2RA
272,5-oligoadenylate449.3IL2, IL2RA
28n acetylcysteine449.2IL2RA, HSPA4, HSPD1
29doxorubicin44 50 1111.2HSPD1, HSPA4, IL2RA
30paraffin449.2IL2RA, HSPA4, HSPD1
31alpha-ketoglutarate449.1HSPA4, HSPD1
32il 10449.1IL2, IL2RA
33creatinine449.1IL2RA, HSPA4, HSPD1
34neomycin449.1IL2, HSPA4, HSPD1
35aspartate449.0IL2RA, HSPA4, HSPD1
36mycophenolate mofetil44 50 1111.0IL2, IL2RA
37pentoxifylline44 1110.0IL2RA, IL2
38adenylate449.0HSPD1, HSPA4, IL2RA
39chloroquine44 2 50 28 1113.0IL2RA, IL2, HSPA4
40herbimycin a44 619.9IL2RA, IL2, HSPA4
415fluorouracil448.9IL2RA, IL2, HSPA4
42rantes448.9HSPD1, IL2, IL2RA
43genistein44 28 61 2 24 1113.8HSPA4, IL2, IL2RA
44cyclosporin a44 28 6110.8IL2RA, IL2, HSPD1
45cisplatin44 50 61 1111.8HSPD1, IL2, IL2RA
46cycloheximide448.7IL2, HSPA4, HSPD1
47h2o2448.7IL2RA, HSPA4, HSPD1
48indomethacin44 28 61 1111.4IL2RA, IL2, HSPA4, HSPD1
49dexamethasone44 50 28 1111.4HSPD1, HSPA4, IL2, IL2RA
50vegf448.4IL2RA, IL2, HSPA4, HSPD1

GO Terms for genes affiliated with Cervicitis

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Biological processes related to Cervicitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chaperone-mediated protein complex assemblyGO:0511319.5HSPA4, HSPD1
2regulation of T cell homeostatic proliferationGO:0460139.1IL2RA, IL2
3response to unfolded proteinGO:0069869.1HSPA4, HSPD1
4positive regulation of activated T cell proliferationGO:0421049.0IL2RA, IL2
5positive regulation of interferon-gamma productionGO:0327299.0HSPD1, IL2
6negative regulation of inflammatory responseGO:0507289.0IL2RA, IL2

Products for genes affiliated with Cervicitis

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  • Antibodies
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Sources for Cervicitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet