Cervicitis malady

Wikipedia: Cervicitis is inflammation of the uterine cervix. Cervicitis in women has many features in common with...⁴⁴ more...

MalaCards: Cervicitis, also known as cervicitis and endocervicitis, is related to carcinoma and cervical cancer. An important gene associated with Cervicitis is MUC5B (mucin 5B, oligomeric mucus/gel-forming), and among its related pathways are STAT3 Pathway and Influenza A. The compounds heparin and atp have been mentioned in the context of this disorder. Affiliated tissues include lymph node, brain and cortex, and related mouse phenotypes are normal and mortality/aging.

Aliases & Descriptions:

cervicitis 6 8 32 cervicitis and endocervicitis 6

uterine cervicitis 43

Diseases related to cervicitis by text searches and GeneDecks gene sharing:

(show top 50)    (show all 1003)

id	Related Disease	Score	Top Affiliating Genes
1	carcinoma	263.1	ZNF217, ZNF384, PIK3CA, PIK3CG, PIN1, LRIG1
2	cervical cancer	252.9	ZNF350, ZNF217, ZNF434, PIK3CA, PIP5KL1, PIK3CG
3	prostatitis	198.3	PIK3CA, PIK3CG, PIN1, LRIG1, KL, RFC1
4	adenocarcinoma	192.4	ZNF217, PIK3CA, PIK3CG, PIN1, NCL, NCR2
5	leukemia	190.5	ZNF384, PIK3CA, PIK3CG, PIN1, RFC1, NCL
6	melanoma	169.8	PIK3CA, PIK3CG, KL, NCL, PDCD1, PDCD1LG2
7	neuronitis	169.7	ZNF384, PIK3CA, PIK3CG, PIN1, NCL, PDE4A
8	hepatocellular carcinoma	166.7	ZNF384, PIK3CA, PIK3CG, PIN1, KL, NCL
9	gastric cancer	162.9	PIK3CA, PIP5KL1, PIK3CG, PIN1, RFC1, NCL
10	thyroiditis	160.7	PIK3CA, PIK3CG, PIN1, RFC1, PDE4A, RECK
11	cervical carcinoma	154.9	ZNF384, PIK3CA, PIK3CG, KL, PDCD1, PDCD1LG2
12	esophagitis	154.1	PIK3CA, PIK3CG, PIN1, PDCD1LG2, PDCD4, PDE4A
13	breast carcinoma	144.3	ZNF217, PIK3CA, PIK3CG, NCL, RECK, KIT
14	neuroblastoma	134.7	PIK3CA, PIK3CG, PIN1, NCL, PDE4A, RECK
15	sarcoma	133.5	ZNF384, PIK3CA, PIK3CG, PDE4A, RECK, RELA
16	hypoxia	133.1	ZNF217, PIK3CA, PIP5KL1, PIK3CG, PDCD4, PDE4A
17	ovarian carcinoma	132.3	PIK3CA, PIP5KL1, PIK3CG, PDCD4, RECK, RELA
18	arthritis	130.7	PIK3CG, PIN1, KL, RFC1, PDCD1, PDCD1LG2
19	rheumatoid arthritis	121.6	PIK3CG, PIN1, KL, RFC1, PDCD1, PDCD1LG2
20	myeloma	115.9	PIK3CA, PIK3CG, NCR1, NCR2, PDE4A, RECK
21	pancreatitis	114.9	PIK3CA, PIK3CG, PIN1, KL, NCL, PDCD1LG2
22	lung carcinoma	113.4	PIK3CA, PIK3CG, RECK, PCNA, RB1, RBL2
23	fibrosis	113.2	PIK3CA, PIK3CG, PIN1, KL, PDE4A, RECK
24	oral squamous cell carcinoma	113.0	PIK3CA, PIN1, PDCD1, PDCD1LG2, PDCD4, RECK
25	colon carcinoma	109.2	PIK3CA, PIK3CG, KL, NCL, PDCD4, CNR1
26	osteosarcoma	107.0	PIK3CA, PIK3CG, RFC1, PDE4A, RECK, RECQL4
27	nasopharyngitis	104.6	PIK3CA, PIK3CG, PDCD1, RECK, RELA, KIT
28	endometrial cancer	102.5	PIK3CA, PIK3CG, PDCD4, RET, KITLG, SFN
29	multiple myeloma	101.1	PIK3CA, PIK3CG, NCR1, RECK, RELA, KIT
30	cerebritis	99.0	PIK3CG, PDE4A, RELA, REN, CNR1, KITLG
31	endometrial carcinoma	97.4	PIK3CA, PIK3CG, RELA, KIT, KIR2DL3, SFN
32	thyroid carcinoma	96.6	PIK3CA, PIK3CG, RECQL4, RET, KIR3DL2, KITLG
33	laryngitis	95.4	PIK3CA, PDCD4, RECQL4, RELA, KIR2DS4, KIR3DL1
34	colon cancer	94.4	PIK3CA, PIK3CG, RFC1, PDCD4, PDE4A, RECK
35	esophageal cancer	92.9	PIK3CA, PIK3CG, PDCD1LG2, PDCD4, CNR1, KITLG
36	retinoblastoma	90.9	PIK3CA, PIK3CG, RFC1, NCL, RECK, KIT
37	peritonitis	86.4	NCR1, NCR2, RELA, REN, RET, KIT
38	oral cancer	83.2	RECK, SFN, SFRP1, SFRP2, PCNA, RB1
39	anemia	82.1	PDCD1, RELA, REN, REV1, KIT, KITLG
40	obesity	81.9	PIK3CA, PIK3CG, NCR3, RECK, RELA, REN
41	adenoma	78.0	PIK3CA, PDCD4, PDE4A, RECK, REN, RET
42	myeloid leukemia	76.0	PIK3CA, PIK3CG, PIN1, NCL, NCR1, NCR2
43	renal cell carcinoma	75.7	PIK3CA, PDCD1, RELA, RET, KIT, SFRP1
44	influenza	74.8	PIK3CA, PIK3CG, NCL, NCR1, NCR2, RECK
45	herpes simplex	74.2	PIK3CA, PIK3CG, NCL, NCR1, NCR2, RECK
46	cervical intraepithelial neoplasia	73.3	PIK3CA, KIAA0226L, KIR3DL2, KIR3DL3, KIR2DL1, KIR2DL3
47	gingivitis	71.9	PIK3CG, CNR1, PCNA, SELE, SETD2, SERPINH1
48	gonococcal synovitis	70.6	PIK3CA, PIK3CG, PDCD1, PDE4A, RECK, RELA
49	cystic fibrosis	67.7	PIK3CG, PDE4A, RECK, REN, VWF, PCNA
50	lymphocytic leukemia	67.3	PIK3CA, PIK3CG, NCL, PDCD1LG2, PDE4A, RECK

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to cervicitis:

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MGI Mouse Phenotypes related to cervicitis:

²⁵ (show all 29)

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	normal phenotype	MP:0002873	INF	LRIG1, NCR1, RELA, REN, RET, REV1
2	mortality/aging	MP:0010768	INF	PIK3CA, KL, NCR1, PDCD1, PDCD1LG2, PDCD4
3	digestive/alimentary phenotype	MP:0005381	INF	LRIG1, KL, RECQL4, RET, KIT, KITLG
4	growth/size phenotype	MP:0005378	INF	ZNF384, PIK3CA, PIK3CG, PIN1, KL, RECK
5	reproductive system phenotype	MP:0005389	INF	ZNF384, PIK3CA, PDCD4, REN, RET, SFN
6	renal/urinary system phenotype	MP:0005367	INF	KL, PDCD1, PDCD4, REN, RET, KIT
7	integument phenotype	MP:0010771	INF	PIK3CG, PIN1, LRIG1, KL, RECK, RECQL4
8	respiratory system phenotype	MP:0005388	INF	KL, RET, NAB2, BRCA1, MYCN, LIF
9	behavior/neurological phenotype	MP:0005386	INF	PIK3CA, KL, REN, CNR1, KIT, RB1
10	endocrine/exocrine gland phenotype	MP:0005379	INF	ZNF384, LRIG1, KL, PDCD4, RET, SFN
11	embryogenesis phenotype	MP:0005380	INF	PIK3CA, RECK, RECQL4, RET, CNBP, KIT
12	vision/eye phenotype	MP:0005391	INF	PIK3CA, PIN1, PDCD1, RECQL4, RELA, CNBP
13	skeleton phenotype	MP:0005390	INF	ZNF384, PIK3CG, RECK, RELA, CNBP, CNR1
14	hearing/vestibular/ear phenotype	MP:0005377	INF	KIT, KITLG, SFN, RB1, RBP1, VDR
15	tumorigenesis	MP:0002006	47.9	PIK3CA, LRIG1, PDCD1LG2, PDCD4, RECQL4, RET
16	no phenotypic analysis	MP:0003012	27.7	PDCD1LG2, RET, CNR1, SFRP1, SFRP2, PCNA
17	liver/biliary system phenotype	MP:0005370	23.1	RECK, KIT, SFN, RBP1, RBL1, SERPINC1
18	pigmentation phenotype	MP:0001186	19.6	RECQL4, KIT, KITLG, RB1, RBP1, SERPINC1
19	other phenotype	MP:0005395	18.4	KL, RECK, CNR1, RBP2, SERPINH1, RARA
20	craniofacial phenotype	MP:0005382	INF	LRIG1, RECQL4, CNBP, KIT, KITLG, RBL1
21	limbs/digits/tail phenotype	MP:0005371	INF	LRIG1, KL, RECK, RECQL4, RELA, RET
22	muscle phenotype	MP:0005369	INF	PIK3CA, PIK3CG, KL, PDCD1, RELA, REN
23	cardiovascular system phenotype	MP:0005385	INF	PIK3CA, PIK3CG, KL, PDCD1, PDE4A, RECK
24	hematopoietic system phenotype	MP:0005397	INF	NCR1, PDCD1, PDCD1LG2, RECQL4, REV1, KIT
25	nervous system phenotype	MP:0003631	INF	LRIG1, KL, PDCD1, PDE4A, RECK, RELA
26	adipose tissue phenotype	MP:0005375	INF	PIK3CA, KL, CNR1, SFRP1, BUB3, RB1
27	homeostasis/metabolism phenotype	MP:0005376	INF	PIK3CA, PIK3CG, KL, PDCD1LG2, RELA, REN
28	immune system phenotype	MP:0005387	INF	KL, PDCD4, PDE4A, RECQL4, REN, REV1
29	cellular phenotype	MP:0005384	INF	PIK3CA, PIK3CG, PIN1, LRIG1, KL, PDCD1

Articles related to cervicitis:

(show top 50)    (show all 2682)

id	Title	Authors	Year	Affiliating Genes
1	Immunohistochemical detection of Raf kinase inhibitor protein in normal cervical tissue and cervical cancer tissue. (21672326)	Hu C.J.... Zhang G.M.	2011	PEBP1
2	Common polymorphisms in methylenetetrahydrofolate red uctase gene are associated with risks of cervical intraepithelial neoplasia and cervical cancer in women with low serum folate and vitamin B12. (21052817)	Tong S.Y.... Lee J.P.	2011	MTHFR
3	High expressions of bcl-2 and survivin, and decreased apoptosis in uterine cervical carcinosarcoma compared to cervical squamous cel l carcinoma. (20668868)	Gan X.L.... Hu L.N.	2011	BCL2, BIRC5
4	Immunolabeling of the inhibin-I^A and -I^B subunit in n ormal and malignant human cervical tissue and cervical cancer cell lines. (21475087)	JA1ckstock J.... Mylonas I.	2010	INHBA, INHBB
5	Expression and clinical implications of homeobox gene Six1 in cervical cancer cell lines and cervical epithelial tissues. (21370601)	Zheng X.H.... Li L.	2010	SIX1
6	P634A4 and TAp73 immunocytochemistry in liquid-based cervical cytology--potential biomarkers for diagnosis and progress prediction o f cervical neoplasia. (20081800)	Cheung A.N.... Ngan H.Y.	2010	TP63, TP73
7	Reduced miR-34a expression in normal cervical tissues and cervical lesions with high-risk human papillomavirus infection. (20442590)	Li B.... Xie X.	2010	MIR34A
8	Association of HLA Class II alleles and haplotypes wi th cervical dystonia: HLA DR13-DQ6 (DQB1*0604) homozygotes are at greatly incre ased risk of cervical dystonia in Caucasian Americans. (20843162)	Deitiker P.R.... Atassi M.Z.	2010	HLA-DQA1, HLA-DQB1, HLA-DRB1
9	Plasma proteome analysis of cervical intraepithelial neoplasia and cervical squamous cell carcinoma. (20093745)	Looi M.L.... Yusof Y.A.	2009	CLEC3B
10	Expression of Aurora kinase A and B in normal and malignant cervical tissue: high Aurora A kinase expression in squamous cervical cancer. (19059698)	Twu N.F.... Chen Y.J.	2009	AURKA, AURKB
11	Effect of apolipoprotein E genotype on the outcome af ter anterior cervical decompression and fusion in patients with cervical spondy lotic myelopathy. (19951017)	Setzer M.... Marquardt G.	2009	APOE
12	Quantitative analysis of heparanase gene expression i n normal cervical, cervical intraepithelial neoplastic, and cervical carcinoma tissues. (19955948)	Varchalama E.... Antsaklis A.	2009	HPSE
13	Methylation markers for CCNA1 and C13ORF18 are strong ly associated with high-grade cervical intraepithelial neoplasia and cervical c ancer in cervical scrapings. (19843677)	Yang N.... Wisman G.B.	2009	CCNA1, KIAA0226L
14	Inhibin/activin-betaE subunit in normal and malignant human cervical tissue and cervical cancer cell lines. (20033758)	Bergauer F.... Mylonas I.	2009	INHBE
15	Expression of p16 and cervical infection with high-risk human papillomavirus are not related to p53 activity in cervical intraepithelial neoplasia. (18021213)	BraganAsa J.F.... Derchain S.	2008	TP53, CDKN2A
16	Regulatory T cells in a spectrum of HPV-induced cervical lesions: cervicitis, cervical intraepithelial neoplasia and squamous cell carcinoma. (18593438)	Adurthi S.... Jayshree R.S.	2008	IL2RA, IL2
17	Microarray analysis of normal cervix, carcinoma in si tu, and invasive cervical cancer: identification of candidate genes in pathogen esis of invasion in cervical cancer. (18217980)	Song J.Y.... Lee K.W.	2008	ARHGAP8
18	Detection of autoantibodies to survivin in cervical mucus from patients with human papillomavirus-associated cervical cancer and precursor lesions. (17364499)	Jimenez L.G.... Rocha-Zavaleta L.	2007	BIRC5
19	Insulin-like growth factor system gene expression in cervical scrapes from women with squamous intraepithelial lesions and cervical cancer. (17709267)	Serrano M.L.... Bravo M.M.	2007	IGFBP3
20	Geographic distribution of cervical cancer-associated human leucocyte antigens and cervical cancer incidence in Finland. (17945045)	Castro F.A.... Lehtinen M.	2007	HLA-S
21	Overexpression of VEGF and TGF-beta1 mRNA in Pap smears correlates with progression of cervical intraepithelial neoplasia to cancer: implication of YY1 in cervical tumorigenesis and HPV infection. (17549406)	Baritaki S.... Spandidos D.A.	2007	TGFB1, YY1
22	Expression and clinical significance of Pin1 and Cyclin D1 in cervical cancer cell lines and cervical epithelial tissues (16536997)	Li H.Y.... Ma D.	2006	PIN1
23	Upregulation of telomerase (hTERT) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus, virus persistence, or disease outcome in cervical cancer. (17041957)	Branca M.... Syrjanen K.	2006	TERT
24	Cervical inflammatory cytokines and other markers in the cervical mucus of pregnant women with lower genital tract infection. (16307744)	Sawada M.... Okai T.	2006	IL8, LTF
25	Extracellular signal-regulated protein kinase is activated in cervical intraepithelial neoplasms but inactivated in invasive cervical carcinoma. (16792545)	Matsuura K.... Moriyama M.	2006	EPHB2, EIF2AK3, MKI67
26	Comparison of DNA hypermethylation patterns in different types of uterine cancer: cervical squamous cell carcinoma, cervical adenocarcinoma and endometrial adenocarcinoma. (16331610)	Kang S.... Lee H.P.	2006	DAPK1, TIMP3, HLTF
27	Over-expression of topoisomerase IIalpha is related to the grade of cervical intraepithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict prognosis in cervical cancer or HPV clearance after cone treatment. (16990717)	Branca M.... Syrjanen K.	2006	TOP2A
28	Survivin as a marker of cervical intraepithelial neoplasia and high-risk human papillomavirus and a predictor of virus clearance and prognosis in cervical cancer. (15923164)	Branca M.... Syrjanen K.	2005	BIRC5
29	Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy. (15629771)	Santin A.D.... Pecorelli S.	2005	TGFB1, SERPINF1, UBE2C
30	p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer. (15858126)	Murphy N.... O'Leary J.J.	2005	CDKN2A, CDC6
31	Detecting cervical cancer by quantitative promoter hypermethylation assay on cervical scrapings: a feasibility study. (15192122)	Reesink-Peters N.... Van der Zee A.G.	2004	DAPK1, MGMT
32	TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia. (14970278)	Steenbergen R.D.... Snijders P.J.	2004	CADM1
33	Apoptosis in cervical cancer cells: implications for adjunct anti-estrogen therapy for cervical cancer. (15517869)	Chen D.... Auborn K.J.	2004	BCL2
34	Altered urinary profiles of polyamines and endogenous steroids in patients with benign cervical disease and cervical cancer. (14607325)	Lee S.H.... Chung B.C.	2003	SRD5A1, PAOX
35	Detection of cervical neoplasia using measurement of Brn-3a in cervical smears with persistent minor abnormality. (12911730)	Sindos M.... Latchman D.	2003	POU4F1
36	A prospective, randomized, controlled cervical fusion study using recombinant human bone morphogenetic protein-2 with the CORNERSTONE-SR allograft ring and the ATLANTIS anterior cervical plate. (12811263)	Baskin D.S.... Widmayer M.A.	2003	BMP2
37	Overexpression of placental tissue protein 17b/TIP47 in cervical dysplasias and cervical carcinoma. (11299819)	Than G.N.... Szekeres G.	2001	PLIN3
38	Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium. (11739883)	Chen D.Z.... Carter T.H.	2001	CASP3
39	Changes in molecular weight of hyaluronan and hyaluronidase activity in uterine cervical mucus in cervical ripening. (11380283)	Obara M.... Tanaka T.	2001	HYAL2
40	Combination of cervical interleukin-6 and -8, phosphorylated insulin-like growth factor-binding protein-1 and transvaginal cervical ultrasonography in assessment of the risk of preterm birth. (11510716)	Kurkinen-RAoty M.... Jouppila P.	2001	IGFBP1
41	Histopathologic subtyping of cervical adenocarcinoma reveals increasing incidence rates of endometrioid tumors in all age groups: a population based study with review of all nonsquamous cervical carcinomas in Norway from 1966 to 1970, 1976 to 1980, and 1986 to 1990. (11002225)	Alfsen G.C.... Abeler V.M.	2000	NOS2
42	Proliferative activity in cervical intraepithelial neoplasia and cervical carcinoma. (11593543)	Xue Y.... Zhang X.	1999	PCNA
43	Differential expression of keratins 10, 17, and 19 in normal cervical epithelium, cervical intraepithelial neoplasia, and cervical carcinoma. (10343611)	Maddox P.... Hanby A.	1999	KRT17, KRT10
44	Immunohistochemical overexpression of p16 protein associated with intact retinoblastoma protein expression in cervical cancer and cervical intraepithelial neoplasia. (9736404)	Sano T.... Nakajima T.	1998	CDKN2A
45	The role of cytokines in cervical ripening: correlati ons between the concentrations of cytokines and hyaluronic acid in cervical muc us and the induction of hyaluronic acid production by inflammatory cytokines by human cervical fibroblasts. (9704773)	Ogawa M.... Tanaka T.	1998	IL8
46	Quantitative determination of the epidermal growth factor receptor in cervical cancer and normal cervical epithelium by 2-color flow cytometry: evidence for down-regulation in cervical cancer. (9291423)	Kimmig R.... Hepp H.	1997	EGFR
47	BCL-2 immunoreactivity increases with severity of CIN: a study of normal cervical epithelia, CIN, and cervical carcinoma. (8691340)	ter Harmsel B.... Ramaekers F.	1996	BCL2
48	Differential response of cervical intraepithelial and cervical carcinoma cell lines to transforming growth factor-beta 1. (7835777)	De Geest K.... Wilbanks G.D.	1994	TGFB1
49	Expression of keratins 1, 6, 15, 16, and 20 in normal cervical epithelium, squamous metaplasia, cervical intraepithelial neoplasia, and cervical carcinoma. (7679549)	Smedts F.... Vooijs P.	1993	KRT1, KRT15
50	Basal-cell keratins in cervical reserve cells and a comparison to their expression in cervical intraepithelial neoplasia. (1372156)	Smedts F.... Vooijs P.	1992	KRT17

Genes related to cervicitis according to GeneCards:

(show top 50)    (show all 1424)

id	Symbol	Description	Score	GeneCards Section Context
1	MUC5B	mucin 5B, oligomeric mucus/gel-forming	11.1	Publications, Aliases & Descriptions, Functions, Summaries
2	POU4F1	POU class 4 homeobox 1	11.0	Publications, Summaries
3	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	11.0	Publications, Summaries
4	POU2F3	POU class 2 homeobox 3	11.0	Publications, Summaries
5	SLPI	secretory leukocyte peptidase inhibitor	11.0	Publications, Summaries
6	CDH3	cadherin 3, type 1, P-cadherin (placental)	11.0	Summaries
7	PAX1	paired box 1	11.0	Publications, Summaries
8	ST20	suppressor of tumorigenicity 20	11.0	Expressions, Aliases & Descriptions, Publications
9	FUNDC2	FUN14 domain containing 2	11.0	Aliases & Descriptions
10	LETMD1	LETM1 domain containing 1	11.0	Publications, Aliases & Descriptions
11	BRI3BP	BRI3 binding protein	11.0	Aliases & Descriptions
12	DGCR	DiGeorge syndrome chromosome region	11.0	Summaries
13	DBNL	drebrin-like	11.0	Aliases & Descriptions
14	STMN2	stathmin-like 2	11.0	Publications, Aliases & Descriptions, Orthologs
15	TMEM50A	transmembrane protein 50A	11.0	Aliases & Descriptions
16	MRPS11	mitochondrial ribosomal protein S11	11.0	Aliases & Descriptions
17	ZNF434	zinc finger protein 434	11.0	Aliases & Descriptions
18	HEXB	hexosaminidase B (beta polypeptide)	11.0	Aliases & Descriptions, Orthologs
19	MCM3	minichromosome maintenance complex component 3	11.0	Aliases & Descriptions
20	TTC23	tetratricopeptide repeat domain 23	11.0	Aliases & Descriptions
21	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	11.0	Aliases & Descriptions
22	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	11.0	Publications, Aliases & Descriptions
23	RBMS1	RNA binding motif, single stranded interacting protein 1	11.0	Aliases & Descriptions
24	WNT6	wingless-type MMTV integration site family, member 6	11.0	Summaries
25	CDKN2A	cyclin-dependent kinase inhibitor 2A	11.0	Publications
26	FHIT	fragile histidine triad	11.0	Publications, Functions
27	IVL	involucrin	11.0	Publications
28	KRT8	keratin 8	11.0	Publications
29	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	11.0	Publications
30	KRT10	keratin 10	11.0	Publications
31	TERC	telomerase RNA component	11.0	Publications
32	IFI27	interferon, alpha-inducible protein 27	11.0	Publications
33	RASSF1	Ras association (RalGDS/AF-6) domain family member 1	11.0	Publications
34	NME1	NME/NM23 nucleoside diphosphate kinase 1	11.0	Publications
35	BIRC5	baculoviral IAP repeat containing 5	11.0	Publications
36	HLA-A	major histocompatibility complex, class I, A	11.0	Publications
37	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	11.0	Publications
38	CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7	11.0	Publications
39	TYMP	thymidine phosphorylase	11.0	Publications
40	DAPK1	death-associated protein kinase 1	11.0	Publications
41	MKI67	antigen identified by monoclonal antibody Ki-67	11.0	Publications
42	SKP2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	11.0	Publications
43	TP53	tumor protein p53	11.0	Publications
44	VEGFC	vascular endothelial growth factor C	11.0	Publications
45	BCL2	B-cell CLL/lymphoma 2	11.0	Publications
46	TP63	tumor protein p63	11.0	Publications
47	TP73	tumor protein p73	11.0	Publications
48	CADM1	cell adhesion molecule 1	11.0	Publications
49	CDK1	cyclin-dependent kinase 1	11.0	Publications
50	EGFR	epidermal growth factor receptor	11.0	Publications

Pathways related to cervicitis according to GeneDecks:

(show top 50)    (show all 238)

id	Pathway	Score	Top Affiliating Genes
1	STAT3 Pathway36	22.9	BRAF, MYC, BMP2, BMP6, BMP7, LIF
2	Influenza A20	20.9	PIK3CA, PIK3CG, RELA, VDAC1, XPO1, JUN
3	Cell Cycle / Checkpoint Control3	20.9	PIN1, RECQL4, PCNA, BUB3, RB1, BRCA1
4	Apoptosis and Autophagy3	20.0	PDCD4, SERPINB5, MYC, MYCN, BID, BIRC2
5	Tuberculosis20	19.9	RELA, VDR, BID, BCL2, BAX, LAMP1
6	Glucocorticoid Receptor Signaling36	19.9	BMP2, BMP6, BMP7, BCL2, BAX, CEBPB
7	Measles20	19.8	PIK3CA, PIK3CG, RELA, CHUK, BBC3, CD28
8	Colorectal Cancer Metastasis36	19.5	BRAF, MYC, BIRC5, BCL2L1, BAX, MSH2
9	Toxoplasmosis20	18.9	PIK3CA, PIK3CG, RELA, BIRC2, BIRC3, BCL2
10	Cell cycle20	18.1	SFN, PCNA, BUB3, RB1, RBL2, RBL1
11	all-trans-Retinoic Acid Signaling in Brain36	18.0	BMP2, BMP6, BMP7, RARA, RARB, LIF
12	Hepatitis C20	17.9	PIK3CA, PIK3CG, RELA, BRAF, CLDN2, CLDN7
13	TGF-beta Signaling Pathways37	17.1	PIK3CG, RELA, BRAF, MYC, MTOR, JUN
14	p53 signaling pathway20	16.8	SFN, SERPINB5, SERPINE1, BID, CHEK1, CHEK2
15	Apoptosis Signaling Pathways37	16.6	SFN, BID, BIRC2, BIRC3, BIRC5, BIRC7
16	PGC1Alpha Pathway36	16.0	BMP2, BMP6, BMP7, BCL2, BAX, CD4
17	Leishmaniasis20	15.9	RELA, JUN, ITGB1, FOS, IRAK1, FCGR2A
18	Signal transduction_AKT signaling41	15.7	PIK3CA, RELA, PCNA, MYC, BCL2L1, CHUK
19	Cell adhesion_ECM remodeling41	15.7	VTN, SERPINE1, VCAN, LAMB3, LAMC2, CD44
20	HGF Pathway36	15.5	RB1, RAP1A, RAPGEF1, JUN, CDKN1B, ITGA1
21	Selected targets of p5310	15.0	SERPINB5, LIF, BCL2, BAX, S100A2, CDKN1A
22	Development Prolactin receptor signaling10	15.0	PIK3CA, RELA, MYC, BCL2, BCL2L1, CEBPB
23	Mucin expression in CF via TLRs, EGFR signaling pathways41	14.9	RELA, CHUK, MUC2, MUC5AC, MUC5B, CFTR
24	Pertussis20	14.9	RELA, JUN, CD14, ITGA5, ITGB1, FOS
25	Allograft rejection20	14.8	CD28, CD86, CD80, CD40, GZMB, IL10
26	Cell adhesion molecules (CAMs)20	14.7	PDCD1LG2, VCAN, CLDN2, CLDN7, SDC1, MPZ
27	Immune response IL-22 signaling pathway10	14.6	MYC, BCL2, BCL2L1, JUN, CD28, CD86
28	Cell cycle Regulation of G1/S transition (part 2)10	14.4	RELA, RB1, RBL2, RBL1, CHUK, JUN
29	Type I diabetes mellitus20	14.2	CD28, CD86, CD80, GZMB, INS, IL12A
30	Signal transduction PTEN pathway10	14.1	PIK3CA, PCNA, MTOR, JUN, CDKN1A, ITGA5
31	Signal transduction_PTEN pathway41	12.0	PCNA, ITGA5, ITGB1, GSK3B, IGF1R, CASP9
32	EGFR Inhibitor Pathway, Pharmacodynamics34	11.2	HRAS, KRAS, STAT5A, STAT5B, RRAS
33	Signal transduction AKT signaling10	11.0	GSK3B
34	PTEN Pathway36	INF	KIT, KITLG, BRAF, VEGFB, VEGFC, BMP2
35	Antioxidant Action of Vitamin-C36	INF	KIT, KITLG, VEGFB, VEGFC, BMP2, BMP6
36	Rho Family GTPases36	INF	KIT, KITLG, VIM, VEGFB, VEGFC, MYLK
37	DHA Signaling36	INF	KIT, KITLG, SERPINF1, VEGFB, VEGFC, BMP2
38	Cytokine-cytokine receptor interaction20	INF	KIT, KITLG, VEGFA, VEGFB, VEGFC, BMP2
39	Renin-Angiotensin Pathway36	INF	REN, KIT, KITLG, VEGFB, VEGFC, VCAM1
40	MAPK Family Pathway36	INF	KITLG, BRAF, VEGFB, VEGFC, BMP2, BMP6
41	Cellular Apoptosis Pathway36	INF	KIT, KITLG, VEGFB, VEGFC, VDAC1, BMP2
42	CREB Pathway36	INF	KIT, KITLG, VEGFB, BMP2, BMP6, BMP7
43	Nuclear Receptor Activation by Vitamin-A36	INF	KIT, KITLG, VEGFB, VEGFC, BMP2, BMP6
44	Actin-Based Motility by Rho Family GTPases36	INF	MYLK, BMP7, BDNF, ITGAL, ITGAV, ITGB4
45	Ras Pathway36	INF	KIT, BRAF, VEGFB, VEGFC, BMP2, BMP7
46	Regulation of eIF4 and p70S6K36	INF	VEGFC, BMP2, BAX, CD4, CD80, ITGA1
47	PPAR Pathway36	INF	KIT, KITLG, VEGFB, VEGFC, BMP2, ITGA1
48	Akt Signaling36	INF	PIK3CG, KIT, VEGFB, VEGFC, BMP2, BMP7
49	Pathways in cancer20	INF	PIK3CA, PIK3CG, RELA, RET, RB1, BRCA2
50	JAK-STAT Pathway36	INF	KIT, KITLG, BRCA1, VEGFB, VEGFC, MYC

Compounds related to cervicitis according to GeneDecks:

(show top 50)    (show all 471)

id	Compound	Score	Top Affiliating Genes
1	heparin32 9 18 9	INF	PIK3CA, PIK3CG, NCL, RECK, KITLG, VWF
2	atp32	43.3	PIK3CA, RFC1, NCL, PDE4A, RECK, RET
3	progesterone32 42 9 18 9	41.1	PIK3CA, PDE4A, KIT, PCNA, RB1, RBP1
4	cholesterol32 9 18 9	35.9	PIK3CA, RECK, REN, CNBP, KITLG, VWF
5	sb 20358032 42	27.1	RB1, SELE, SETD2, VIM, BSG, BRAF
6	glucose32	26.0	PDE4A, KIT, GCH1, SETD2, SERPINA2, SERPINF1
7	adriamycin32	25.3	RB1, VIM, BRCA1, BRCA2, VDR, MYC
8	camptothecin32 42 9 9	27.7	PIK3CG, NCL, PCNA, RB1, SETD2, BRCA1
9	forskolin32 42 9 9	27.5	PDE4A, REN, VIM, VIP, BRAF, MYLK
10	fatty acid32	24.0	RECK, SFN, GC, RBP1, RBP2, BRAF
11	chloramphenicol32 9 9	25.9	GC, SELE, SERPINC1, SETD2, SERPINE1, VIM
12	bromodeoxyuridine32	23.2	PIK3CA, KITLG, PCNA, RB1, VIM, MYC
13	ethanol32 34 9 18 9	27.2	KL, KITLG, RBP1, SERPINA1, BMP7, RARB
14	folate32	21.9	RECK, VWF, GCH1, SELE, SERPINC1, SERPINA3
15	troglitazone32 42 9 9	24.7	PIK3CG, RB1, SELE, SERPINE1, VDR, VCAM1
16	pdtc32	20.6	PIK3CA, PIK3CG, SELE, SETD2, SERPINB5, VCAM1
17	gtp32	20.3	PIK3CA, RECK, GCH1, VIP, BRAF, VDAC1
18	formaldehyde32 18	20.9	KIT, VWF, PCNA, RB1, SELE, VIM
19	bortezomib32 9 9	21.7	SETD2, BRCA1, VEGFA, MYC, BID, BIRC5
20	gf 109203x32 42	20.1	PIK3CG, KITLG, VEGFA, RAP1A, CFTR, JUN
21	trastuzumab32 34 9 9	21.5	PIK3CA, PIK3CG, KIT, VEGFC, BIRC5, KDR
22	hyaluronic acid32 18	19.4	VTN, VIM, VCAN, MYC, BMP6, CHI3L1
23	hydrocortisone32 9 9	20.2	REN, KITLG, VIM, BMP6, LIF, KDR
24	potassium32 9 18 9	20.6	PIK3CA, PDE4A, REN, KITLG, KIR3DL1, VTN
25	histidine32	17.5	PDE4A, KITLG, RARA, LHCGR, LGALS1, CHEK1
26	crcs32	17.1	PIK3CA, RB1, BRAF, RASSF1, BIRC5, MUC1
27	nacl32	16.9	REN, SERPINA3, VDAC1, VCAN, BMP7, LIG4
28	chloroquine32 34 9 9	19.9	KIT, VTN, SERPINC1, BRCA1, BMP6, LDLR
29	simvastatin32 34 42 9 18 9	21.8	KITLG, VWF, SELE, SERPINE1, VEGFA, VCAM1
30	dutp32	16.6	PCNA, BIRC5, CLU, PARP1, BCL2, BCL2L1
31	carbon32	16.4	CNR1, VWF, VTN, PCNA, VDR, LDLR
32	acth32	15.9	REN, SERPINA1, VIP, BDNF, LHCGR, LGALS3
33	ns 39832 42	15.9	PIK3CG, PCNA, PARP1, CDKN1B, MMP1, FGF2
34	raloxifene32 9 9	16.9	VWF, SERPINC1, SERPINE1, VDR, BMP2, CKB
35	ionomycin32	14.7	SETD2, SERPINA3, RAP1A, CHUK, JUNB, CD274
36	cetuximab32 34 9 9	17.4	BRAF, KDR, CDKN1B, CDKN3, AREG, FCGR2A
37	b 72332	14.4	PCNA, VIM, CHGA, MUC1, MUC16, S100A1
38	ibuprofen32 9 18 9	17.3	VCAM1, BMP6, BDNF, LEP, CHUK, CGB5
39	corticosterone32 18	15.2	CNR1, VIP, LIF, BDNF, LHCGR, CGB5
40	bcnu32	14.1	PARP1, MPG, CDKN2A, MGMT, GSR, GSTP1
41	allergens32	14.0	PDCD1, CMA1, LGALS3, S100A8, CD79A, CD86
42	ndga32	13.9	VCAM1, JUN, MMP13, MMP3, FOS, IL1B
43	aphidicolin32	13.9	PCNA, RB1, BRCA1, MYC, CHEK1, CHEK2
44	pd15303532	13.8	PIK3CG, VEGFA, BIRC5, JUN, MMP1, AREG
45	budesonide32 42 9 9	14.6	PDE4A, KITLG, CD36, ANXA1, IGHE, F2RL1
46	capsaicin32	INF	CNR1, SELE, VIP, CMA1, BDNF, LEP
47	dexamethasone32 42 34 9 9	INF	PIK3CA, PDE4A, REN, KITLG, VWF, VTN
48	calcium32 9 18 9	INF	PIN1, KL, NCL, PDE4A, RECK, RELA
49	retinoid32	INF	RBP1, RBP2, VIM, VDR, MYC, MYCN
50	azathioprine32 34 9 9	INF	PCNA, VIM, BMP2, RARB, RASSF1, LIF

Cellular components related to cervicitis according to GeneDecks:

(show all 13)

id	Name	GO ID	Score	Top Affiliating Genes
1	plasma membrane	GO:005886	INF	PIK3CG, LRIG2, KL, PDCD1, PDCD1LG2, RECK
2	extracellular region	GO:005576	INF	KL, PDCD1LG2, KITLG, VWF, VTN, GC
3	cytoplasm	GO:005737	INF	PIP5KL1, PIK3CG, PIN1, LRIG2, PDCD4, RECQL4
4	extracellular space	GO:005615	INF	KL, REN, KIT, KITLG, VTN, SFN
5	nucleoplasm	GO:005654	34.5	ZNF217, PIN1, RFC1, RELA, REV1, PCBP1
6	integral to plasma membrane	GO:005887	29.5	KL, NCR1, NCR2, NCR3, RET, CNR1
7	cell surface	GO:009986	19.1	SFRP1, VEGFA, VCAM1, BMP2, RARA, LGALS1
8	external side of plasma membrane	GO:009897	18.1	KIT, VWF, VCAM1, KDR, LDLR, LAMP1
9	extracellular matrix	GO:031012	14.6	VWF, VTN, SFRP1, SFRP2, PCOLCE, SERPINF1
10	membrane raft	GO:045121	14.0	SELE, BSG, P2RX7, CD79A, CD36, CD14
11	platelet alpha granule lumen	GO:031093	12.6	VWF, SERPINA1, SERPINE1, VEGFA, VEGFB, VEGFC
12	nucleus	GO:005634	INF	ZNF350, ZNF384, ZNF434, PIN1, NCL, PDCD4
13	cytosol	GO:005829	INF	PIK3CA, PIK3CG, PDCD4, PDE4A, RELA, CNBP

Biological processes related to cervicitis according to GeneDecks:

(show top 50)    (show all 56)

id	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of apoptotic process	GO:043066	INF	PIK3CG, RELA, SFRP1, SERPINE1, BRAF, VEGFA
2	signal transduction	GO:007165	INF	NCR1, NCR2, PDCD1, PDE4A, RET, KIT
3	positive regulation of transcription from RNA polymerase II promoter	GO:045944	INF	RELA, CNBP, SFRP2, RB1, RBL1, SERPINE1
4	cell-cell signaling	GO:007267	INF	SFRP2, BMP2, CHST4, S100A9, CGB, CD86
5	apoptotic process	GO:006915	30.8	PDCD1, PDCD4, SFN, VIM, BRCA1, VDAC1
6	response to drug	GO:042493	24.4	PDE4A, REN, SFRP1, SFRP2, VEGFC, MYC
7	negative regulation of cell proliferation	GO:008285	23.1	WARS, SFN, SFRP1, SFRP2, RBBP4, VDR
8	virus-host interaction	GO:019048	22.7	RELA, WAPAL, RB1, RBL1, VIM, VDAC1
9	negative regulation of transcription, DNA-dependent	GO:045892	22.1	ZNF350, ZNF217, PDCD4, RELA, SFRP1, SFRP2
10	immune response	GO:006955	21.9	NCR3, PDCD1LG2, KIR2DL1, KIR2DL3, KIR3DL1, VTN
11	blood coagulation	GO:007596	21.3	PIK3CA, PIK3CG, VWF, SERPINC1, SERPINB2, SERPINA1
12	cell proliferation	GO:008283	20.8	KITLG, SFN, PCNA, SERPINF1, NAB2, NANOG
13	innate immune response	GO:045087	20.5	PIK3CG, PIN1, RELA, CLU, BCL2, BCL2L1
14	anti-apoptosis	GO:006916	20.3	PIK3CA, RELA, SERPINB2, BRAF, VEGFB, BNIP3
15	cytokine-mediated signaling pathway	GO:019221	20.0	PIN1, RELA, KIT, VCAM1, B2M, CD44
16	inflammatory response	GO:006954	19.7	PIK3CG, NCR3, RELA, KIT, SELE, SERPINA3
17	positive regulation of apoptotic process	GO:043065	18.9	CNR1, SFRP1, SFRP2, BMP2, RARB, BID
18	cell adhesion	GO:007155	18.7	KITLG, VWF, VTN, VCAM1, VCAN, CIB1
19	induction of apoptosis	GO:006917	18.5	GCH1, NACC1, BOK, BNIP3, USP7, BBC3
20	response to hypoxia	GO:001666	17.8	SERPINA1, VEGFA, VCAM1, BNIP3, MYOCD, BMP2
21	cell surface receptor signaling pathway	GO:007166	17.5	BSG, BIRC2, BIRC3, BAG1, P2RX7, P2RY1
22	response to organic cyclic compound	GO:014070	17.1	SFRP1, SERPINA1, BAK1, P2RX7, MSH2, JUN
23	cell cycle arrest	GO:007050	16.5	RB1, MYC, RASSF1, ZAK, BARD1, MSH2
24	response to lipopolysaccharide	GO:032496	16.1	CNR1, GCH1, SELE, SERPINA1, S100A7, S100A8
25	platelet activation	GO:030168	16.1	PIK3CA, PIK3CG, VWF, SERPINA1, SERPINE1, VEGFA
26	positive regulation of protein phosphorylation	GO:001934	15.6	PIN1, VEGFA, BMP2, MTOR, P2RY1, AXIN1
27	positive regulation of cell migration	GO:030335	15.5	RET, VIL1, VEGFA, MYLK, BMP2, KDR
28	positive regulation of ERK1 and ERK2 cascade	GO:070374	15.4	BRAF, VEGFB, BMP2, KDR, CHI3L1, S100A7
29	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO:006919	15.3	BOK, MYC, BCL2L10, BBC3, BAX, CDKN1B
30	regulation of cell proliferation	GO:042127	15.3	PIN1, KIT, SERPINE1, BRCA1, BID, BIRC2
31	response to ethanol	GO:045471	15.1	CNR1, BCL2, BAK1, S100A8, S100A9, CDK1
32	induction of apoptosis by intracellular signals	GO:008629	15.1	BNIP3, MYC, BID, CLU, BCL2, BCL2L1
33	response to estradiol stimulus	GO:032355	15.0	GC, SERPINA1, BRCA2, VDR, RARA, BID
34	aging	GO:007568	15.0	KL, CNR1, SERPINF1, VDR, VCAM1, BAK1
35	regulation of immune response	GO:050776	14.4	KIR3DL2, KIR2DL1, KIR2DL3, KIR2DL4, KIR3DL1, KIR2DL2
36	positive regulation of peptidyl-tyrosine phosphorylation	GO:050731	14.3	KITLG, VTN, VEGFA, VEGFB, LIF, MTOR
37	leukocyte migration	GO:050900	14.0	PIK3CA, BSG, CD58, CD244, ITGA3, ITGA5
38	cellular response to mechanical stimulus	GO:071260	13.8	BNIP3, CHEK1, BAK1, CD40, ITGB1, IRF1
39	platelet degranulation	GO:002576	13.8	VWF, SERPINA1, SERPINE1, VEGFA, VEGFB, VEGFC
40	positive regulation of neuron apoptotic process	GO:043525	13.5	BAG1, BAX, ATM, JUN, CDK5, ITGA1
41	MAPK cascade	GO:000165	13.4	RET, MYC, CDK1, INS, FGFR1, FGFR3
42	positive regulation of smooth muscle cell proliferation	GO:048661	13.2	JUN, CDH13, MNAT1, IL13, IL6, IL6R
43	positive regulation of cell proliferation	GO:008284	INF	CNBP, KIT, SFRP1, SFRP2, VIP, NACC1
44	response to mechanical stimulus	GO:009612	INF	BMP2, CHI3L1, P2RX7, P2RY1, JUN, JUNB
45	positive regulation of gene expression	GO:010628	INF	KIT, BRAF, VEGFA, VDR, BMP2, CDK1
46	positive regulation of MAPK cascade	GO:043410	INF	KIT, LIF, KDR, LEP, P2RX7, CD36
47	angiogenesis	GO:001525	INF	PIK3CA, PIK3CG, NCL, WARS, SETD2, SERPINE1
48	positive regulation of transcription, DNA-dependent	GO:045893	INF	RELA, RET, CNBP, SFRP1, RB1, BRCA1
49	negative regulation of transcription from RNA polymerase II promoter	GO:000122	INF	VDR, MYC, MYB, MYOCD, BMI1, BMP2
50	transforming growth factor beta receptor signaling pathway	GO:007179	INF	RBL1, SERPINE1, MYC, ZFYVE9, PARP1, UCHL5

Molecular functions related to cervicitis according to GeneDecks:

(show all 14)

id	Name	GO ID	Score	Top Affiliating Genes
1	protein binding	GO:005515	INF	ZNF350, ZNF217, PIK3CA, PIK3CG, PIN1, RFC1
2	cytokine activity	GO:005125	INF	KITLG, VEGFA, BMP2, BMP6, BMP7, LIF
3	identical protein binding	GO:042802	19.6	RELA, SFRP1, PCNA, VIL1, VIM, BNIP3
4	transcription factor binding	GO:008134	17.8	RELA, RB1, RBL1, NAB2, MYC, MYOCD
5	enzyme binding	GO:019899	17.7	BRCA1, RARA, BIRC5, BIRC7, ZFHX3, AXIN1
6	receptor binding	GO:005102	17.0	REN, SERPINE1, BMP2, RARA, LIF, PAOX
7	transcription regulatory region DNA binding	GO:044212	15.8	ZNF217, RELA, BRCA1, ZFHX3, YY1, XRCC5
8	double-stranded DNA binding	GO:003690	15.1	RBMS1, MYC, YBX1, XRCC5, XRCC6, MSH2
9	sequence-specific DNA binding transcription factor activity	GO:003700	INF	ZNF217, RELA, CNBP, RB1, NANOG, VDR
10	growth factor activity	GO:008083	INF	KITLG, VEGFA, VEGFB, VEGFC, BMP2, BMP6
11	protein kinase binding	GO:019901	INF	RELA, VIM, ZFP36, PARK2, BCL2L1, BCL2L14
12	ATP binding	GO:005524	INF	PIK3CA, PIP5KL1, PIK3CG, RFC1, RECQL4, RET
13	heparin binding	GO:008201	INF	VTN, SFRP1, PCOLCE, SERPINC1, VEGFA, VEGFB
14	protein homodimerization activity	GO:042803	INF	KIT, VWF, GCH1, VIL1, VEGFA, VEGFB